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Generated by SRI International Pathway Tools Version 25.0, Authors S Authors: Pallavi Subhraveti Peter D Karp Ingrid Keseler An online version of this diagram is available at BioCyc.org. Biosynthetic pathways are positioned in the left of the cytoplasm, degradative pathways on the right, and reactions not assigned to any pathway are in the far right of the cytoplasm. Transporters and membrane proteins are shown on the membrane. Anamika Kothari Periplasmic (where appropriate) and extracellular reactions and proteins may also be shown. Pathways are colored according to their cellular function. Gcf_000223375Cyc: Ketogulonicigenium vulgare WSH-001 (GCF_000223375) Cellular Overview Connections between pathways are omitted for legibility. Ron Caspi a sulfonate a sulfonate L-arabinose L-arabinose L-arabinose L-arabinose L-arabinose spermidine nitrate nitrate phosphate D-galactose D-galactose D-galactose D-galactose D-galactose 3+ 3+ putrescine L-ornithine L-ornithine L-ornithine L-ornithine a sulfonate a sulfonate a sulfonate a sulfonate a sulfonate hydrogencarbonate hydrogencarbonate a sulfonate Fe Fe an amino glycine betaine D-allose D-allose D-allose D-allose D-allose spermidine spermidine spermidine sn-glycerol sn-glycerol spermidine lys lys lys lys molybdate molybdate molybdate molybdate nitrate nitrate nitrate nitrate nitrate nitrate thiosulfate thiosulfate thiosulfate thiosulfate thiosulfate thiosulfate spermidine spermidine ammonium a glycerophosphodiester acid L-carnitine phosphate phosphate phosphate benzoate hydrogencarbonate hydrogencarbonate hydrogencarbonate hydrogencarbonate hydrogencarbonate hydrogencarbonate D-xylose D-xylose D-xylose D-xylose D-xylose putrescine putrescine putrescine putrescine putrescine 3-phosphate 3-phosphate putrescine choline predicted ABC predicted ABC predicted predicted transporter of transporter of ABC ABC PB0098 KVU_2496 KVU_0297 PB0053 KVU_1006 KVU_1894 KVU_1895 KVU_0233 KVU_0526 KVU_0096 KVU_1056 KVU_1292 KVU_1634 nitrate/a sulfonate/ nitrate/a sulfonate/ KVU_0910 KVU_0388 KVU_0573 KVU_0488 KVU_0487 KVU_2595 PA0090 KVU_2007 KVU_1633 KVU_0560 KVU_0104 KVU_1105 KVU_1362 KVU_1158 PB0133 KVU_0826 KVU_0829 KVU_2162 KVU_2165 transporter PB0188 KVU_0065 KVU_2162 PB0154 PA0175 transporter KVU_1298 KVU_1527 KVU_2400 KVU_1473 hydrogencarbonate hydrogencarbonate of spermidine/ of phosphate putrescine 3+ 3+ a sulfonate a sulfonate a sulfonate a sulfonate a sulfonate a sulfonate L-arabinose L-arabinose L-arabinose L-arabinose L-arabinose Fe spermidine Fe spermidine spermidine sn-glycerol sn-glycerol spermidine glycine betaine L-ornithine L-ornithine L-ornithine L-ornithine molybdate molybdate molybdate molybdate thiosulfate thiosulfate thiosulfate thiosulfate thiosulfate thiosulfate ammonium a glycerophosphodiester an amino phosphate phosphate phosphate benzoate nitrate nitrate nitrate nitrate nitrate nitrate D-galactose D-galactose D-galactose D-galactose D-galactose spermidine putrescine spermidine putrescine putrescine 3-phosphate 3-phosphate putrescine L-carnitine lys lys lys lys hydrogencarbonate hydrogencarbonate hydrogencarbonate hydrogencarbonate hydrogencarbonate a sulfonate a sulfonate hydrogencarbonate D-allose D-allose D-allose D-allose D-allose putrescine putrescine acid choline spermidine phosphate nitrate nitrate D-xylose D-xylose D-xylose D-xylose D-xylose hydrogencarbonate hydrogencarbonate putrescine Hormone Biosynthesis Aminoacyl-tRNA Charging glutaminyl-tRNA gln β biosynthesis via transamidation ditrans,octacis- a peptidoglycan with 3-phenyl-2- ditrans,octacis- UDP-N-acetyl- an N-acetyl- - a [lipoyl-carrier an [amino group Macromolecule Modification a [glutamine- a lipid II 6 folate chitin indole-3-acetate selenate reduction Inorganic Nutrient Metabolism undecaprenyldiphospho- (L-alanyl-γ-D-glutamyl- oxopropanoate tyr undecaprenyldiphospho- α-D-muramoyl- D-hexosaminide protein]-N -[(R) met carrier protein]- Aromatic Compound Biosynthesis hypotaurine degradation inosine ATP synthetase]- biosynthesis taurine degradation I N-acetyl-(N-acetyl-β-D- L-lysyl-D-alanyl-D- N-acetyl-(N- L-alanyl-γ-D- -dihydrolipoyl]- bifunctional C-terminal-γ- glu IV (bacteria) tRNA processing glucosaminyl)muramoyl- alanine) pentapeptide acetylglucosaminyl) L-tyrosine glutamyl-meso-2,6- L-lysine (L-glutamate 5- chorismate biosynthesis I selenate D-alanyl-D-alanine glycoside pyruvate,2- ornithine peptidase glycoside (indole-3-yl) dipicolinate biosynthesis hypotaurine L-alanyl-γ-D-glutamyl-L- aspartate/ muramoyl-L-alanyl-γ- diaminopimeloyl- semialdehyde-2-N-acetyl- sulfate taurine carboxypeptidase: hydrolase oxoglutarate acetyltransferase/ dimerization hydrolase acetonitrile a polycistronic aminotransferase L-cysteine degradation III lysyl-D-alanyl-D-alanine tyrosine/aromatic D-isoglutaminyl-N-(β- inosine-uridine glutamate- D-alanyl-D-alanine yl)-L-glutamategamma- D-erythrose adenylyltransferase: KVU_0432 family 3 dehydrogenase N-acetylglutamate domain- family 3 tRNA precursor urea cycle class-III: tpa aminotransferase D-asparaginyl)-L-lysyl- preferring ammonia-ligase glutamyl- 4-phosphate KVU_0107 D-alanyl-D-alanine domain- complex, synthase: mutT containing domain- (indol-3-yl) 3-deoxy-7- asp 2-sulfinoacetaldehyde aminotransferase protein: KVU_1260 D-alanyl-D-alanine nucleoside hydrolase adenylyltransferase: bcp phosphate an L-glutamyl- [+ 2 isozymes] glycosyltransferase, D-alanyl-D-alanine carboxypeptidase: containing dihydrolipoamide bifunctional protein: containing an [amino group acetamide phosphoheptulonate aspartokinase: adenosine 5'- cys class-III: tpa transmembrane reductase: Gln ribonuclease ribonuclease family 51: mrcB aminotransferase, glutamate- carboxypeptidase: dacC protein: dehydrogenase ornithine protein: [tRNA ] synthase: KVU_0849 phosphoselenate arg KVU_PB0140 carrier protein]-argC gln synthetase/ 3-deoxy- KVU_2518 E: rne E: rne classes I and protein: KVU_2259 ammonia-ligase KVU_0432 KVU_0011 E3 component: acetyltransferase/ KVU_0011 γ aspartyl/ peptidoglycan glycosyltransferase, C-terminal- - amidase D-arabino- L-aspartyl- sulfoacetaldehyde II superfamily [+ 4 isozymes] adenylyltransferase: KVU_1453 N-acetylglutamate glutamyl-tRNA ala glycosyltransferase: family 51: mrcB D-alanyl-D-alanine a N- [+ 2 isozymes] [+ 2 isozymes] (5-phospho- YgiC: heptulosonate 4-phosphate a tRNA precursor a tRNA precursor argininosuccinate protein: tyrB glnE synthase: argJ aspartyl/ amidotransferase acetaldehyde pbpA peptidoglycan carboxypeptidase: D-ala acetylglucosamine- dihydrolipoamide glutamate pteroate L-glutamyl)- KVU_1994 7-phosphate with a 5' with a 5' lyase: KVU_0151 ammonium N-acetyl-L- glutamyl-tRNA subunit B: aspartate- selenite 3-mercaptopyruvate 3-(4- glycosyltransferase: D-ribofuranose dacC -N-acetylmuramyl- an N-acetyl-β- dehydrogenase, N-acetyl-D- L-glutamate [+ 2 isozymes] 3-dehydroquinate extension and extension and a aldehyde a [glutamine methionine chitin amidotransferase: KVU_0517 semialdehyde Argininosuccinate a peptidoglycan with di-trans,octa-cis hydroxyphenyl) pbpA hypoxanthine (tetrapeptide) an alcohol D-hexosamine FAD/NAD(P) glucosamine synthase domain a long 3' trailer short 3' extension carbamoyl dehydrogenase phe synthetase]-O pepN gatB (indol-3-yl)acetate dehydrogenase, lyase 2: asaL (L-alanyl-γ-D-glutamyl- -undecaprenyl pyruvate UDP-N- pyrophosphoryl- -binding, [+ 4 isozymes] protein: aroB inner phosphate family protein: ald 3-mercaptopyruvate 4 [+ 11 isozymes] USG-1 related L-lysyl-D-alanyl-D- diphosphate a peptidoglycan di-trans,octa-cis -(5'-adenylyl) D-ala acetylmuramoyl- undecaprenol component of the a 5-phosphooxy- membrane L-arginino- synthetase, sulfurtransferase: 3-dehydroquinate protein: asd L-ornithine aldehyde alanine) pentapeptide dimer (E. faeciums) -undecaprenyl -L-tyrosine L-alanyl-γ-D- 2-oxoglutarate ammonium L-glutamyl- protein succinate glutamine sseA Gln ribonuclease selenodiglutathione dehydrogenase diphosphate dehydrogenase: [tRNA ] L-aspartate 4- exonuclease: translocase amidotransferase glutamyl-meso-2,6- 3-dehydroquinate D: rnd family protein: aldA 3-mercaptopyruvate hydrogen sulfide a [lipoyl-carrierlpdA semialdehyde KVU_2186 component small subunit: carA diaminopimeloyl- aspartyl/ dehydratase: aroQ exonuclease: sulfurtransferase: biosynthesis I D-alanine protein]-N 6 - Dihydrodipicolinate ribonuclease YidC: rnpA acetate glutamyl-tRNA 3-dehydroquinate KVU_2186 carbamoyl KVU_1838 lipoyl-L-lysine synthase family D: rnd a tRNA precursor Ornithine amidotransferase dehydratase: phosphate cys protein: dapA with a short glutathioselenol Argininosuccinate carbamoyltransferase subunit B: aroQ1 3' extension synthase hydrogen sulfide pyruvate a peptidoglycan dimer an sn-glycero-3- sn-glycero-3- an N-terminal a peptide with dihydrodipicolinate protein: argF ditrans,octacis- a nucleoside a reduced c- KVU_0517 (ISS): argG with pentapeptide phospho-N-(acyl) phospho-N- L-alanyl-[S18 RNA an N-terminal carbonic acid 3-dehydroshikimate synthase dGTP undecaprenyldiphospho- a purine ribonucleoside xanthosine triphosphate type cytochrome ATP [+ 4 isozymes] a tRNA L-citrulline 3-mercaptopyruvate stems (meso- ethanolamine (arachidonoyl) protein of L-proline biotin protein: dapA N-acetyl-(N- Thiol shikimate 5- precursor with ribonuclease polyphosphate metabolism diaminopimelate acetylglucosaminyl) ethanolamine 30S ribosome]alanine (2S,4S)-4- 3-mercaptopyruvate peroxidase transcriptional an L-glutaminyl- dehydrogenase: hydroxy-2,3,4,5- a 5' extension D: rnd hydrogen selenide containing) muramoyl-L-alanyl- acetyltransferase DNA- (Atypical 2-Cys sulfate activation glyphosate degradation II sulfurtransferase: glycerophosphoryl alpha/beta
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