Authors: Pallavi Subhraveti Peter D Karp Ingrid Keseler An online version of this diagram is available at BioCyc.org. Biosynthetic pathways are positioned in the left of the cytoplasm, degradative pathways on the right, and reactions not assigned to any pathway are in the far right of the cytoplasm. Transporters and membrane proteins are shown on the membrane. Anamika Kothari Periplasmic (where appropriate) and extracellular reactions and proteins may also be shown. Pathways are colored according to their cellular function. Gcf_000223375Cyc: Ketogulonicigenium vulgare WSH-001 (GCF_000223375) Cellular Overview Connections between pathways are omitted for legibility. Ron Caspi a sulfonate a sulfonate L-arabinose L-arabinose L-arabinose L-arabinose L-arabinose spermidine nitrate nitrate phosphate D-galactose D-galactose D-galactose D-galactose D-galactose 3+ 3+ putrescine L-ornithine L-ornithine L-ornithine L-ornithine a sulfonate a sulfonate a sulfonate a sulfonate a sulfonate hydrogencarbonate hydrogencarbonate a sulfonate Fe Fe an amino glycine betaine D-allose D-allose D-allose D-allose D-allose spermidine spermidine spermidine sn-glycerol sn-glycerol spermidine lys lys lys lys molybdate molybdate molybdate molybdate nitrate nitrate nitrate nitrate nitrate nitrate thiosulfate thiosulfate thiosulfate thiosulfate thiosulfate thiosulfate spermidine spermidine ammonium a glycerophosphodiester acid L-carnitine phosphate phosphate phosphate benzoate hydrogencarbonate hydrogencarbonate hydrogencarbonate hydrogencarbonate hydrogencarbonate hydrogencarbonate D-xylose D-xylose D-xylose D-xylose D-xylose putrescine putrescine putrescine putrescine putrescine 3-phosphate 3-phosphate putrescine choline predicted ABC predicted ABC predicted predicted transporter of transporter of ABC ABC PB0098 KVU_2496 KVU_0297 PB0053 KVU_1006 KVU_1894 KVU_1895 KVU_0233 KVU_0526 KVU_0096 KVU_1056 KVU_1292 KVU_1634 nitrate/a sulfonate/ nitrate/a sulfonate/ KVU_0910 KVU_0388 KVU_0573 KVU_0488 KVU_0487 KVU_2595 PA0090 KVU_2007 KVU_1633 KVU_0560 KVU_0104 KVU_1105 KVU_1362 KVU_1158 PB0133 KVU_0826 KVU_0829 KVU_2162 KVU_2165 transporter PB0188 KVU_0065 KVU_2162 PB0154 PA0175 transporter KVU_1298 KVU_1527 KVU_2400 KVU_1473 hydrogencarbonate hydrogencarbonate of spermidine/ of phosphate putrescine

3+ 3+ a sulfonate a sulfonate a sulfonate a sulfonate a sulfonate a sulfonate L-arabinose L-arabinose L-arabinose L-arabinose L-arabinose Fe spermidine Fe spermidine spermidine sn-glycerol sn-glycerol spermidine glycine betaine L-ornithine L-ornithine L-ornithine L-ornithine molybdate molybdate molybdate molybdate thiosulfate thiosulfate thiosulfate thiosulfate thiosulfate thiosulfate ammonium a glycerophosphodiester an amino phosphate phosphate phosphate benzoate nitrate nitrate nitrate nitrate nitrate nitrate D-galactose D-galactose D-galactose D-galactose D-galactose spermidine putrescine spermidine putrescine putrescine 3-phosphate 3-phosphate putrescine L-carnitine lys lys lys lys hydrogencarbonate hydrogencarbonate hydrogencarbonate hydrogencarbonate hydrogencarbonate a sulfonate a sulfonate hydrogencarbonate D-allose D-allose D-allose D-allose D-allose putrescine putrescine acid choline spermidine phosphate nitrate nitrate D-xylose D-xylose D-xylose D-xylose D-xylose hydrogencarbonate hydrogencarbonate putrescine

Hormone Biosynthesis Aminoacyl-tRNA Charging glutaminyl-tRNA gln β biosynthesis via transamidation ditrans,octacis- a peptidoglycan with 3-phenyl-2- ditrans,octacis- UDP-N-acetyl- an N-acetyl- - a [lipoyl-carrier an [amino group Macromolecule Modification a [glutamine- a lipid II 6 folate chitin indole-3-acetate selenate reduction Inorganic Nutrient Metabolism undecaprenyldiphospho- (L-alanyl-γ-D-glutamyl- oxopropanoate tyr undecaprenyldiphospho- α-D-muramoyl- D-hexosaminide protein]-N -[(R) met carrier protein]- Aromatic Compound Biosynthesis hypotaurine degradation inosine ATP synthetase]- biosynthesis taurine degradation I N-acetyl-(N-acetyl-β-D- L-lysyl-D-alanyl-D- N-acetyl-(N- L-alanyl-γ-D- -dihydrolipoyl]- bifunctional C-terminal-γ- glu IV (bacteria) tRNA processing glucosaminyl)muramoyl- alanine) pentapeptide acetylglucosaminyl) L-tyrosine glutamyl-meso-2,6- L-lysine (L-glutamate 5- chorismate biosynthesis I selenate D-alanyl-D-alanine glycoside pyruvate,2- ornithine peptidase glycoside (indole-3-yl) dipicolinate biosynthesis hypotaurine L-alanyl-γ-D-glutamyl-L- aspartate/ muramoyl-L-alanyl-γ- diaminopimeloyl- semialdehyde-2-N-acetyl- sulfate taurine carboxypeptidase: oxoglutarate acetyltransferase/ dimerization hydrolase acetonitrile a polycistronic aminotransferase L-cysteine degradation III lysyl-D-alanyl-D-alanine tyrosine/aromatic D-isoglutaminyl-N-(β- inosine-uridine glutamate- D-alanyl-D-alanine yl)-L-glutamategamma- D-erythrose adenylyltransferase: KVU_0432 family 3 dehydrogenase N-acetylglutamate domain- family 3 tRNA precursor urea cycle class-III: tpa aminotransferase D-asparaginyl)-L-lysyl- preferring ammonia- glutamyl- 4-phosphate KVU_0107 D-alanyl-D-alanine domain- complex, synthase: mutT containing domain- (indol-3-yl) 3-deoxy-7- asp 2-sulfinoacetaldehyde aminotransferase protein: KVU_1260 D-alanyl-D-alanine nucleoside hydrolase adenylyltransferase: bcp phosphate an L-glutamyl- [+ 2 isozymes] glycosyltransferase, D-alanyl-D-alanine carboxypeptidase: containing dihydrolipoamide bifunctional protein: containing an [amino group acetamide phosphoheptulonate aspartokinase: adenosine 5'- cys class-III: tpa transmembrane reductase: Gln ribonuclease ribonuclease family 51: mrcB aminotransferase, glutamate- carboxypeptidase: dacC protein: dehydrogenase ornithine protein: [tRNA ] synthase: KVU_0849 phosphoselenate arg KVU_PB0140 carrier protein]-argC gln synthetase/ 3-deoxy- KVU_2518 E: rne E: rne classes I and protein: KVU_2259 ammonia-ligase KVU_0432 KVU_0011 E3 component: acetyltransferase/ KVU_0011 γ aspartyl/ peptidoglycan glycosyltransferase, C-terminal- - amidase D-arabino- L-aspartyl- sulfoacetaldehyde II superfamily [+ 4 isozymes] adenylyltransferase: KVU_1453 N-acetylglutamate glutamyl-tRNA ala glycosyltransferase: family 51: mrcB D-alanyl-D-alanine a N- [+ 2 isozymes] [+ 2 isozymes] (5-phospho- YgiC: heptulosonate 4-phosphate a tRNA precursor a tRNA precursor argininosuccinate protein: tyrB glnE synthase: argJ aspartyl/ amidotransferase acetaldehyde pbpA peptidoglycan carboxypeptidase: D-ala acetylglucosamine- dihydrolipoamide glutamate pteroate L-glutamyl)- KVU_1994 7-phosphate with a 5' with a 5' : KVU_0151 ammonium N-acetyl-L- glutamyl-tRNA subunit B: aspartate- selenite 3-mercaptopyruvate 3-(4- glycosyltransferase: D-ribofuranose dacC -N-acetylmuramyl- an N-acetyl-β- dehydrogenase, N-acetyl-D- L-glutamate [+ 2 isozymes] 3-dehydroquinate extension and extension and a aldehyde a [glutamine methionine chitin amidotransferase: KVU_0517 semialdehyde Argininosuccinate a peptidoglycan with di-trans,octa-cis hydroxyphenyl) pbpA hypoxanthine (tetrapeptide) an alcohol D-hexosamine FAD/NAD(P) glucosamine synthase domain a long 3' trailer short 3' extension carbamoyl dehydrogenase phe synthetase]-O pepN gatB (indol-3-yl)acetate dehydrogenase, lyase 2: asaL (L-alanyl-γ-D-glutamyl- -undecaprenyl pyruvate UDP-N- pyrophosphoryl- -binding, [+ 4 isozymes] protein: aroB inner phosphate family protein: ald 3-mercaptopyruvate 4 [+ 11 isozymes] USG-1 related L-lysyl-D-alanyl-D- diphosphate a peptidoglycan di-trans,octa-cis -(5'-adenylyl) D-ala acetylmuramoyl- undecaprenol component of the a 5-phosphooxy- membrane L-arginino- synthetase, sulfurtransferase: 3-dehydroquinate protein: asd L-ornithine aldehyde alanine) pentapeptide dimer (E. faeciums) -undecaprenyl -L-tyrosine L-alanyl-γ-D- 2-oxoglutarate ammonium L-glutamyl- protein succinate glutamine sseA Gln ribonuclease selenodiglutathione dehydrogenase diphosphate dehydrogenase: [tRNA ] L-aspartate 4- exonuclease: amidotransferase glutamyl-meso-2,6- 3-dehydroquinate D: rnd family protein: aldA 3-mercaptopyruvate hydrogen sulfide a [lipoyl-carrierlpdA semialdehyde KVU_2186 component small subunit: carA diaminopimeloyl- aspartyl/ dehydratase: aroQ exonuclease: sulfurtransferase: biosynthesis I D-alanine protein]-N 6 - Dihydrodipicolinate ribonuclease YidC: rnpA acetate glutamyl-tRNA 3-dehydroquinate KVU_2186 carbamoyl KVU_1838 lipoyl-L-lysine synthase family D: rnd a tRNA precursor Ornithine amidotransferase dehydratase: phosphate cys protein: dapA with a short glutathioselenol Argininosuccinate carbamoyltransferase subunit B: aroQ1 3' extension synthase hydrogen sulfide pyruvate a peptidoglycan dimer an sn-glycero-3- sn-glycero-3- an N-terminal a peptide with dihydrodipicolinate protein: argF ditrans,octacis- a nucleoside a reduced c- KVU_0517 (ISS): argG with pentapeptide phospho-N-(acyl) phospho-N- L-alanyl-[S18 RNA an N-terminal carbonic acid 3-dehydroshikimate synthase dGTP undecaprenyldiphospho- a purine ribonucleoside xanthosine triphosphate type cytochrome ATP [+ 4 isozymes] a tRNA L-citrulline 3-mercaptopyruvate stems (meso- ethanolamine (arachidonoyl) protein of L-proline biotin protein: dapA N-acetyl-(N- Thiol shikimate 5- precursor with ribonuclease polyphosphate metabolism diaminopimelate acetylglucosaminyl) ethanolamine 30S ribosome]alanine (2S,4S)-4- 3-mercaptopyruvate peroxidase transcriptional an L-glutaminyl- dehydrogenase: hydroxy-2,3,4,5- a 5' extension D: rnd hydrogen selenide containing) muramoyl-L-alanyl- acetyltransferase DNA- (Atypical 2-Cys sulfate activation glyphosate degradation II sulfurtransferase: glycerophosphoryl alpha/beta regulator Gln KVU_2375 thiosulfate long chain deoxyguanosinetriphosphate γ-D-isoglutaminyl- inosine/uridine- inosine/uridine- (Ribosomal) directed RNA biotin-- [tRNA ] tetrahydrodipicolinate exonuclease: KVU_1838 diester glycerophosphoryl peroxiredoxin) hydrolase protein, LysR inner disproportionation for sulfonation polyphosphate triphosphohydrolase: KVU_1491 N-(β-D-asparaginyl) preferring nucleoside preferring protein: KVU_0315 polymerase: acetyl-CoA- tRNA charging shikimate KVU_2186 murein phosphodiesterase: diester : KVU_0055 fold protein: family protein: membrane IV (rhodanese) glyphosate 3-mercaptopyruvate -L-lysyl-D-alanine hydrolase: KVU_0571 nucleoside ribosomal- KVU_2110 carboxylase sulfate Deoxyguanosinetriphosphate hydrolase: lrgB KVU_PB0185 phosphodiesterase di-heme KVU_PB0178 KVU_PA0259 protein sulfurtransferase: triphosphohydrolase- [+ 4 isozymes] hydrolase: protein-alanine rpoC rpoB ligase: dipicolinate translocase thiosulfate sulfate phosphatase, sseA [+ 2 isozymes] glycerophosphoryl protein: glpQ cytochrome [+ 3 isozymes] [+ 3 isozymes] lys a tRNA Lys a tRNA Ala ala tRNA asp asp 4-hydroxyphenylpyruvate like protein: KVU_1788 KVU_0571 acetyltransferase: [+ 2 isozymes] KVU_1809 component adenylyltransferase: Ppx/GppA , glycosyltransferase, diester glycerophosphoryl an N-terminal N c peroxidase sulfate PA0090 sulfate thr Thr elongator tRNA Met met initiator tRNA Met met glu a tRNA glu biosynthesis inorganic [+ 4 isozymes] KVU_0390 a tRNA YidC: rnpA KVU_0107 family protein: FAD-binding hydrogen sulfide a peptidoglycan dimer L-alanyl-γ-D- family 51: mrcB D-ribofuranose phosphodiesterase diester -acetyl-L-alanyl- family Cys shikimate 3- 3-mercaptopyruvate polyphosphate/ cys a tRNA KVU_0378 protein: with pentapeptide stem glutamyl-meso-2,6- peptidoglycan a purine base protein: glpQ phosphodiesterase: protein: ccpR a peptide pro CO H O biotinyl-5'- phosphate sulfurtransferase: [+ 2 isozymes] ATP-NAD [S18 protein of 2 2 Gly Phe Pro Trp Lysyl-tRNA ser alanyl-tRNA Ile Tyr His Val Arg Leu aspartyl-tRNA triphosphate RNA gly a tRNA phe a tRNA pro a tRNA trp a tRNA ser a tRNA ile a tRNA tyr a tRNA his a tRNA val a tRNA arg a tRNA leu a tRNA tyr APS phosphatase, KVU_2544 2'-deoxyguanosine (meso-diaminopimelate diaminopimeloyl- glycosyltransferase: KVU_PB0185 30S ribosome] an oxidized c- adenylate Threonyl-tRNA methionine--tRNA methionine--tRNA glutamyl-tRNA synthetase LysS: lysK synthetase, class synthetase: KVU_2591 asn tRNA Asn gln a tRNA Gln 3-phosphoshikimate 1- KVU_1838 kinase: ppnK D-ribofuranose xanthine sulfate KVU_2007 sulfate aminotransferase, Ppx/GppA containing) D-alanyl-D-alanine pbpA type cytochrome synthetase / ligase protein: csaA ligase protein: csaA synthetase: gltX lysyl-tRNA synthetase cysteinyl-tRNA IIc:Phosphoesterase, tRNA synthetase carboxyvinyltransferase: [+ 2 isozymes] [+ 3 isozymes] sn-glycerol an N- classes I and sulfate family protein: (aminomethyl) glycyl-tRNA phenylalanyl-tRNA Ser-tRNA(Thr) methionyl-tRNA methionyl-tRNA prolyl-tRNA synthetase Tryptophanyl-tRNA glutamyl-tRNA (PoxA-like protein) synthetase, seryl-tRNA DHHA1:Alanyl-transfer isoleucyl-tRNA tyrosyl-tRNA histidyl-tRNA valyl-tRNA Arginyl-tRNA Leucyl-tRNA class II (D, K and N) aroA adenylyltransferase: glyoxylate 3-phosphate acylethanolamine sn-glycerol 5-enolpyruvoyl- II superfamily KVU_1186 phosphonate a peptidoglycan di-trans,octa-cis anandamide synthetase: glyS glyQ synthetase: pheS pheT hydrolase: thrS synthetase: metG synthetase: metG protein: proS synthetase: trpS synthetase 2: KVU_1658 : KVU_1127 class Ia: cysS synthetase: serS RNA synthetase: alaS synthetase IleS: ileS synthetase: tyrS synthetase: hisS synthetase: valS synthetase, class I: argS synthetase protein: leuS subfamily protein: aspS thiocyanate sulfite KVU_1999 3-phosphate sulfate KVU_1633 sulfate shikimate 3- protein: tyrB an uncharged Alcohol Degradation dimer (E. faecium -undecaprenyl phosphate aspartate/ tRNA PAPS long chain , tetrapeptide) diphosphate a glycyl-[tRNA Gly ] an L-phenylalanyl-[tRNA Phe ] an L-threonyl-[tRNA Thr ] an L-methionyl-[elongator tRNA Met ] an L-methionyl-[initiator tRNA Met ] an L-prolyl-[tRNA Pro ] an L-tryptophanyl-[tRNA Trp ] an L-glutamyl-[tRNA Glu ] an L-lysyl-[tRNA Lys ] an L-cysteinyl-[tRNA Cys ] an L-seryl-[tRNA ser ] an L-alanyl-[tRNA Ala ] an L-isoleucyl-[tRNA Ile ] an L-tyrosyl-[tRNA Tyr ] an L-histidyl-[tRNA His ] an L-valyl-[tRNA Val ] an L-arginyl-[tRNA Arg ] an L-leucyl-[tRNA Leu ] an L-aspartyl-[tRNA asp ] an L-asparaginyl-[tRNA Asn ] an L-glutaminyl-[tRNA Gln ] tyrosine/aromatic polyphosphate ethanol degradation II aminotransferase glycerophosphodiester a peptidoglycan dimer (meso ditrans,octacis- 3-benzyl-3,6 - phosphoenol an N-acyl- N-acetyl-α- (3R,5S)-3- sulfate KVU_0560 sulfate 3-(4- protein: KVU_1260 degradation coenzyme A AsbD acyl- glycerophosphoserine lauroyl-CoA H O H O seleno-L- cob(II)inamide -diaminopimelate containing) 2 2 bis(cysteinylglycine) D-muramoyl- hydroxy-1- hydroxyphenyl) ethanol ATP undecaprenyldiphospho- carrier protein ATP dGDP pyruvate D-glutamate homocysteine chorismate - 6-(hydroxymethyl) L-alanine(1-) pyrroline-5- pyruvate lipoprotein posttranslational alcohol dehydrogenase a glycerophosphodiester N-acetyl-(N- methionine modification acetylglucosaminyl) -diketopiperazine synthase: carboxylatepyrroline-5- sulfate KVU_0104 sulfate GroES-like protein: adhC glycerophosphoryl D-alanyl-D-alanine glycerophosphoryl putative N-acyl-D- muramoyl-L-alanyl-γ-D- acyl murein KVU_1843 carboxylate , Carrier, and Vitamin Biosynthesis a [prolipoprotein]- alcohol dehydrogenase diester Cobalamin carboxypeptidase: diester esterase/lipase/ RepA glutamate isoglutaminyl-L-lysyl- carrier dipeptidase pyruvate hydrolase: reductase: L-cysteine GroES-like phosphodiesterase: adenosyltransferase, KVU_0432 phosphodiesterase: thioesterase;acyl- partitioning deacylase methionine Amine and Polyamine Biosynthesis methylmalonyl-CoA (glycyl) -D-alanyl-D-alanine protein protein/ AC: kinase: lrgB synthase, KVU_0477 prolipoprotein protein: KVU_2498 KVU_PB0185 D-alanyl-D-alanine 5 KVU_PB0185 coa thioester protein: sulfate KVU_1105 sulfate [2Fe-2S] iron-sulfur synthase KVU_0070 pykA pyrroline-5- cob(II)yrinate a,c- flavin biosynthesis I (bacteria and plants) ubiquinol-8 biosynthesis (prokaryotic) pyridoxal 5'-phosphate biosynthesis I adenosylcobinamide-GDP superpathway of heme b biosynthesis from uroporphyrinogen-III tetrahydrofolate biosynthesis L-ascorbate diacylglyceryl acetaldehyde glycerophosphoryl mutase cofactor carboxypeptidase: hydrolase protein: ATPase, ParA KVU_1003 [+ 2 isozymes] vitamin-B12 cluster biosynthesis AcpS: glycerophosphoryl carboxylate diamide biosynthesis II salvage from cobinamide I biosynthesis III putrescine : lgt diester biosynthesis dacC glycosyltransferase, KVU_PA0186 type: repA independent: aldehyde dehydrogenase acpS diester reductase: (late cobalt incorporation) D-erythrose (7,8-dihydropterin- biosynthesis I putrescine phosphodiesterase protein: KVU_2125 family 51: mrcB [+ 5 isozymes] 3-benzyl-3,6 - N-acetyl-D- KVU_2213 L-cysteine desulfurase all-trans-octaprenyl uroporphyrinogen-III prolipoprotein family protein: ald phosphodiesterase putative esterase/ pyruvate proC GTP 4-hydroxybenzoate 4-phosphate cob(II)inamide 6-yl)methyl 4-aminobenzoate D-sorbitol biosynthesis III superpathway of glucose and xylose degradation Carbohydrate Degradation protein: glpQ a peptidoglycan with peptidoglycan bis(cysteinyl)- 6- gly dGTP a carboxylate ala muramate SeMet predicted uroporphyrinogen-III diphosphate diacylglyceryl protein: glpQ lipase/thioesterase: D-glt Hyp Cobalamin diphosphate sorbitol Entner-Doudoroff pathway I aldehyde dehydrogenase sn-glycerol a holo-[AsbD acyl- + (hydroxymethyl) ABC Secondary Metabolite Biosynthesis arg transferase: adenosylcobinamide D,D cross-links (meso- D-ala glycosyltransferase: 3',5'-ADP KVU_PB0175 phosphate H sulfate sulfate DNA-binding bifunctional adenosyltransferase, dehydrogenase: arg D-glucopyranose family protein: aldA 3-phosphate triphosphate carrier protein] ADP -diketopiperazine transporter GTP UbiA KVU_0368 diaminopimelate containing) pbpA transcriptional uroporphyrin-III C- superpathway of heme b methylmalonyl-CoA sldC 6-phosphate D-glucopyranose sn-glycerol of sulfate activator 3HPP- methyltransferase/ cyclohydrolase prenyltransferase: biosynthesis from glycine 4-phospho- a [prolipoprotein]- acetate ser mutase cofactor sorbitol methylerythritol phosphate pathway II 6-phosphate 3-phosphate binding protein: siroheme II/3,4-dihydroxy- KVU_PA0200 D-erythronate coproporphyrinogen III myo-inositol agmatine S-1,2-diacyl-sn- glucose-6- a peptidoglycan di-trans,octa-cis laurate 2-butanone biosynthesis 7,8- dehydrogenase: biosynthesis phosphate 1- glucose-6- -undecaprenyl predicted KVU_0202 synthase: ureE 4-hydroxybenzoate erythronate- D-glyceraldehyde L-ornithine glyceryl-L-cysteine acetate-CoA ligase, AMP- dimer (S. aureus) 4-phosphate gly [corrinoid protein: KVU_2125 dihydropteroate sldC pyruvate hydrolase dehydrogenase: phosphate 1- dependent: KVU_1477 DHAP diphosphate ABC [+ 2 isozymes] precorrin-1 polyprenyltransferase: 4-phosphate Coproporphyrinogen III oxygen-independent 3-phosphate D-glucopyranose sulfate sulfate synthase: ribA 5-aminolevulinate adenosyltranferase]- bifunctional keto-L-sorbose arginase signal zwf dehydrogenase: transporter 2,5-diamino-6- ubiA dehydrogenase: oxidase, aerobic: hemF coproporphyrinogen 6-phosphate Ornithine zwf of sulfate an S-sulfanyl-[L- synthase 1: hemA cob(II)inamide folylpolyglutamate family peptidase 6-phospho acetyl-CoA 6 (5-phospho-D- serA III oxidase: hemN 1-deoxy-D- decarboxylase: a 2-deoxy-D- a [protein]- an O - an N-terminal L- phosphoenol a peptide with a [protein] with a (1->4)- cysteine desulfurase] 5-aminolevulinate synthase/ protein: II: lspA D-glucono- 6-phospho cob(II)alamin a nucleobase an alkylated DNA oleoyl-CoA H O a uracil in DNA an ADP-sugar xylulose-5- KVU_1200 methylguanine 2 alanyl-[S5 protein an N-terminal C-terminal α- α-D-glucan ribosylamino) 3-octaprenyl-4- (3R)-3-hydroxy-2-oxo- protoporphyrinogen IX oxygen-independent dihydrofolate 1,5-lactone D-glucono- ATP ribosyl-base L-cysteine ATP dADP pyruvate a protein KVU_0431 a protein phosphate Ins(3)P speB in DNA 4'-phosphopantetheine of 30S ribosome] L-alanine L-glutamate 1,4-alpha- pyrimidin- hydroxybenzoate Delta- 4 phosphooxybutanoate coproporphyrinogen synthase: folC putrescine an (S-diacyl-sn- 1,5-lactone alanine precorrin-2 [corrinoid L-sorbosone synthase a lipoprotein 6-phosphogluconolactonase: glucan 4(3H)-one aminolevulinic acid phosphoserine III oxidase: KVU_2244 putrescine glyceryl)-L-cysteinyl- 6-phosphogluconolactonase: nucleoside 2- acetyltransferase uracil-DNA nudix adenosyltranferase]- 7,8-dihydrofolate 2: dxs myo-inositol-1(or 4) signal peptide pgl DNA-O6- 3-methyladenine putative branching an S-sulfanyl-[cysteine riboflavin dehydratase: hemB aminotransferase protoporphyrinogen [apolipoprotein] pgl Cobalamin deoxyribosyltransferase (Ribosomal) glycosylase: aspartyl/ hydrolase, Peptidase, cob(I)inamide monoglutamate -monophosphatase D-gluconate methylguanine-- phosphopantetheine DNA glycosylase esterase/lipase/ pyruvate a sugar PB0006 a sugar desulfurase]-[disordered- biosynthesis protein: serC D-glyceraldehyde oxidase: hemG nitrilase/cyanide adenosyltransferase, protein: KVU_1532 protein: KVU_0315 ung glutamyl-tRNA YffH M28 family superpathway of heme b porphobilinogen pyruvate Cobalamin protoporphyrinogen IX 1-deoxy-D-xylulose protein: suhB 6-phosphate D-gluconate protein-cysteine S- adenylyltransferase protein: thioesterase;acyl- kinase: (Alpha form scaffold protein 2-octaprenylphenol 4-phosphooxy- 3-phosphate L-sorbosone hydratase and methylmalonyl-CoA ribosomal- amidotransferase family: trgB protein: biosynthesis from glutamate adenosyltransferase, 5-phosphate [+ 2 isozymes] Tetrapyrrole Biosynthesis 6-phosphate nucleoside 2- methyltransferase/ (Pantetheine-Phosphate KVU_PA0114 coa thioester uracil-DNA pykA amylase protein] complex precorrin-3A RibD: ribD L-threonine 1,4-lactone apolipoprotein N- 6-phosphogluconate mutase cofactor protein-alanine subunit B: pepN KVU_PB0143 [cysteine desulfurase]-S- 5-amino-6-(5- methylmalonyl-CoA Phosphogluconate deoxyribosyltransferase transcriptional adenylyltransferase) 3-methyladenine hydrolase protein: glycosylase: protein) 1-deoxy-D- 1-deoxy-D-xylulose myo-inositol acyltransferase: a peptide dehydrogenase: gntZ biosynthesis acetyltransferase: an α-D-aldose predicted sulfanylcysteine:[acceptor phospho-D- putative4- mutase cofactor a 7,8-dihydrofolate glucose/ dehydratase protein: protein: KVU_2255 regulator Ada: protein: coaD DNA glycosylase KVU_PA0186 KVU_PB0135 : glgB glu xylulose-5- 5-phosphate siroheme biosynthesis KVU_0825 protein: KVU_2125 KVU_0390 1-phosphate α ABC protein]-cysteine ribosylamino)uracil hydroxythreonine- biosynthesis molybdopterin biosynthesis sorbosone D-ribulose KVU_PB0156 KVU_2053 protein: putative esterase/ an N-terminal N pyruvate AMP a (1,6)- -D- a sugar a sugar glutamyl-tRNA 3-(all-trans-octaprenyl) preuroporphyrinogen phosphate reductoisomerase: dxr [+ 3 isozymes] dATP ala a peptide glu a peptide transporter sulfurtransferase: sufS riboflavin 4-phosphate protein: KVU_2125 protoporphyrin IX dehydrogenase- 5-phosphate KVU_1408 lipase/thioesterase: -acetyl-L-alanyl- glucosyl-(1,4) D-ribulose synthetase: gltX an N-acyl-(S-diacyl- a 2-deoxy-D- transcriptional an apyrimidinic uracil α of a sugar a [cysteine desulfurase]- biosynthesis benzene-1,2-diol dehydrogenase synthase like protein: sndH uroporphyrinogen-III KDGP adenosylcobalamin a nucleobase 3'-dephospho-CoA KVU_PB0175 [S5 protein of - -glucan precorrin-3B 5-phosphate glutamyl-tRNA uroporphyrinogen 2: dxs cys MEP bifunctional uroporphyrin- sn-glyceryl)-L- Fatty Acid and Lipid Degradation triphosphate ribosyl-base regulator site in DNA S-sulfanyl-[disordered- protein 3-demethylubiquinone- 1: pdxA adenosylcobinamide ferrochelatase: d-ribulose-5- ribose-5- a DNA containing 30S ribosome] form scaffold GTP synthetase 2: KVU_1658 III synthase ATP L-ascorbate III C-methyltransferase/ cysteinyl-[lipoprotein] Ada: ada an alkylated predicted RibD: ribD Glu 9 3-methyltransferase: 3-amino-1- hemH a tetrahydrofolate phosphate phosphate cyclohydrolase an L-glutamyl-[tRNA ] HEM4: KVU_2181 bifunctional 2-C- oleate β-oxidation nucleobase an apurinic/ protein] complex 5-amino-6-(5- ubiG hydroxyacetone 1-deoxy-D-xylulose DNA-binding siroheme synthase: ureE 3-epimerase 2-dehydro-3- triacylglycerol oleate ABC DNA-binding II/3,4-dihydroxy- methyl-D-erythritol precorrin-1 D-xylose apyrimidinic site a sugar a sugar phospho-D- 2-methoxy-6-(all-trans uroporphyrinogen-III 1-phosphate 5-phosphate protoheme transcriptional protein: cbbE A: rpiA deoxyphosphogluconate degradation a guanine in DNA a [protein]-S- transporter transcriptional 2-butanone activator 3HPP- 4-phosphate methyl-L-cysteine of a sugar precorrin-4 ribitylamino)uracil -octaprenyl)phenol xylose aldolase/4-hydroxy-2- oleate activator 3HPP- 4-phosphate pyridoxine 5'- adenosyl-cobinamide binding protein: GTP cytidylyltransferase/ queuosine a triacyl-sn isomerase D-xylulose D-ribose 5- oxoglutarate aldolase binding protein: synthase: ribA phosphate phosphate KVU_0202 a carboxy- 2-C-methyl-D- biosynthesis I (de novo) Long-chain- -glycerol predicted domain- 5-phosphate phosphate subfamily protein: eda an (S-diacyl-sn- an O 4 - L-alanyl-γ-D- a [protein]-L- a glucosylated KVU_0202 1-deoxy-L- (S)-4-amino-5-oxopentanoate synthase: pdxJ adenylated erythritol 2,4- fatty-acid-- an L-1- a [protein]- lipid II (meso a [protein]-L- an L-asparaginyl- ABC folate transformations III (E. coli) [+ 2 isozymes] phosphopantothenate flagellar glyceryl)-L-cysteinyl- palmitoyl-CoA H O methylthymine glycerophosphoglycerol (R)-glycerate glutamate-O 5 cyclodiphosphate precorrin-2 preQ containing 2 diaminopimelate glutamyl-L-lysyl- a tRNA precursor β-isoaspartate ala UDP-N-acetyl- Asn glycogenin a sugar a sugar [+ 2 isozymes] glycero-tetrulose adenosylcobalamin an [L-cysteine [small subunit of 0 CoA ligase: phosphatidylethanolamine L-cysteine [tRNA ] transporter ARP 2-methoxy-6-all trans- coproporphyrinogen III biosynthesis I protein: transketolase D-glyceraldehyde biosynthetic [apolipoprotein] in DNA D-alanyl-D-alanine hydroxypyruvate protein-L- α -methyl-ester 1,4-alpha- an S-sulfanyl-[cysteine precorrin-5 4-phosphate salvage from cobalamin desulfurase]-S- molybdopterin synthase: ispDF pyruvate KVU_1613 containing) -D-muramate of a sugar octaprenyl-1,4-benzoquinol adenosylcobinamide- (8S)-3',8-cyclo-7,8- bifunctional uroporphyrin- KVU_1355 1: tktA 3-phosphate protein reductase protein: isoaspartate O- glucan desulfurase]-S- Coproporphyrinogen III pyridoxine 5'-phosphate a tetrahydrofolate sulfanyl-L-cysteine synthase] 3-methyl-2- 2-C-methyl-D- 2-octaprenyl- GDP dihydroguanosine III C-methyltransferase/ glyceraldehyde- FliP: fliP nitrilase/cyanide putative esterase/lipase/ glycerophosphoryl KVU_1085 methyltransferase: branching sulfanyl-[disordered- 6,7-dimethyl-8- oxidase, aerobic: hemF cob(I)alamin oxobutanoate erythritol 4-phosphate preQ [+ 4 isozymes] D-sedoheptulose D-glyceraldehyde oleoyl-CoA DNA-O6- glycosyltransferase, D-alanyl-D-alanine ribonuclease UDP-N- chemotaxis peptidyl- 6-methoxy-1,4- siroheme synthase: ureE 1 a 1,2-diacyl- thioesterase;acyl-coa diester predicted form scaffold ribityllumazine 5-aminolevulinate pyridoxamine 5'-triphosphate 3-phosphate hydratase and methylguanine-- family 51: mrcB carboxypeptidase: D: rnd D-isomer specific KVU_0690 response tRNA enzyme benzoquinol methionine cytidylyltransferase: D-xylulose 7-phosphate 3-phosphate sn-glycerol thioester hydrolase phosphodiesterase acetylmuramate- ABC protein] complex synthase: ribH protoporphyrinogen IX 5''-phosphate queuine tRNA- dehydrogenase: apolipoprotein N- protein-cysteine S- KVU_0432 2-hydroxyacid protein-L- regulator: hydrolase: (Alpha a sugar a sugar [cysteine desulfurase]-S- Delta-aminolevulinic methylase: ubiE synthase: ispD sirohydrochlorin protein: KVU_PA0186 peptidoglycan protein: glpQ exonuclease: -alanine ligase transporter precorrin-6A oxidase: pdxH a thiocarboxylated ribosyltransferase: tgt gapB acyltransferase: methyltransferase/ dehydrogenase isoaspartate O- cheB pth amylase sulfanylcysteine:[acceptor acid dehydratase: hemB 6-methoxy-3-methyl- cob(II)alamin KVU_1843 4-(cytidine 5'- carbohydrate transaldolase: glycosyltransferase: D-alanyl-D-alanine KVU_2186 protein: murC of a sugar 6,7-dimethyl-8-(1- protoporphyrinogen [small subunit of cyclic bifunctional uroporphyrin- a 7-aminomethyl-7- cutE putative esterase/lipase/ transcriptional glycerophosphoryl family protein: methyltransferase: protein) protein]-cysteine 2-all-trans-octaprenyl- PLP dihydropteroate synthase, 2-dehydropantoate diphospho)-2-C- kinase FGGY: KVU_1236 (2E,9Z)- pbpA carboxypeptidase: III C-methyltransferase/ 34 13-DPG thioesterase: KVU_PB0175 regulator Ada: diester : glgB sulfurtransferase: sufS D-ribityl)lumazine porphobilinogen oxidase: hemG Cobalamin molybdopterin pyranopterin methyl-D-erythritol deazaguanosine KVU_0490 octadecenoyl-CoA [+ 3 isozymes] dacC KVU_0372 βKVU_2520 UDP-N-acetyl- α a [cysteine 1,4-benzoquinol DHPS:Homocysteine S- siroheme synthase: ureE a 2-acylglycerol KVU_2053 phosphodiesterase: a nucleoside 5'- a protein L- - a [protein]- - predicted 6,7-dimethyl-8- adenosyltransferase, synthase] phosphate Ketopantoate 4-diphosphocytidyl- in tRNA D-erythrose di-trans,octa-cis a tRNA hydroxypyruvate α-D-muramoyl- MeOH asn tRNA Asn a glycogen desulfurase]-(S- protoporphyrin IX methyltransferase:Cobalamin- Xylulokinase F6P phosphoglycerate an N-acyl-(S-diacyl- lipid II (meso KVU_PB0185 monophosphate isoaspartate L-glutamate ABC ribityllumazine methylmalonyl-CoA reductase 2-C-methyl-D- S-adenosylmethionine- 4-phosphate a 2-acyl-1-lyso- transcriptional γ α a sugar a sugar sulfanyl) -[disordered- precorrin-6B dependent methionine: metH siroheme protein: xylBch kinase: pgk sn-glyceryl)-L- palmitate diaminopimelate -undecaprenyl L-alanyl- -D- -methyl ester L-alanine transporter 2 mutase cofactor molybdopterin ApbA/PanE- erythritol kinase: -tRNA phosphatidylethanolamine regulator form scaffold synthase: ribH D-xylulose containing) diphosphate glutamyl-L- D-ala of a sugar biosynthesis glycine cleavage system synthase like protein: KVU_0123 ribosyltransferase- 3-phospho- (S)-3-hydroxy-(9Z) cysteinyl-[lipoprotein] Ada: ada protein] complex riboflavin 3-demethylubiquinol-8 ferrochelatase: hemH 5-phosphate glycerol sn-glycerol lysyl-D-alanine preuroporphyrinogen NAD de novo biosynthesis protein: KVU_2125 a 7,8-dihydrofolateaminomethyltransferase a 5-methyltetrahydrofolate subunit KVU_PB0063 2-phospho-4-(cytidine isomerase: queA D-glycerate -octadecenoyl-CoA synthase I (from aspartate) lipoate glycerol 3-phosphate predicted 3-demethylubiquinone- cob(II)alamin- T: gcvT MoaD: moaD β 5'-diphospho)-2-C- 34 transketolase phosphoglycerate NAD-binding 3- a fatty acid subunit uroporphyrinogen protoheme -alanine (R)-pantoate an epoxyqueuosine D-mannose a [protein]-S- ABC 9 3-methyltransferase: [corrinoid salvage II methyl-D-erythritol 1: tktA mutase, 2,3- hydroxyacyl-CoA a thymine in DNA a sugar a sugar precorrin-7 alpha: ribE III synthase in tRNA degradation methyl-L-cysteine transporter a [cysteine desulfurase]- ubiG asp adenosyltranferase] molybdopterin a [lipoyl-carrier bifunctional 2-C- D-glyceraldehyde bisphosphoglycerate- dehydrogenase: of a sugar HEM4: KVU_2181 6 D-mannopyranose [scaffold protein- riboflavin L-aspartate protein]-N - methyl-D-erythritol 3-phosphate independent: gpmI KVU_1278 ubiquinol-8 lipoyl-L-lysine 4-phosphate 6-phosphate N 6 -dimethylallyladenosine 37 a reduced N-acetyl-muramoyl-(L- decaprenyl- a (1->4)- (2Fe-2S)] complex uroporphyrinogen-III oxidase: sdhA mannose-6- 2-phospho- 3-oxo-(9Z)- a sulfurated ubiquinone-6 sn-glycero-3- (R)-glycerate an aromatic ADP-D-ribose sn-glycerol an L-cysteinyl- predicted FMN 5,10- a (6S)-5- 34 glyceraldehyde- acetone degradation electron-transfer alanyl-γ-D-glutamyl-L- pyrophosphoryl-(N a PII protein α-D-glucan 2-iminosuccinate cytidylyltransferase/ a queuosine phosphate octadecenoyl-CoA in tRNA phosphoethanolamine ATP roseoflavin 3-phosphate [tRNA Cys ] adenylyltransferase / cob(I)alamin- methylenetetrahydrofolate formyltetrahydrofolate 3-phosphate D-glycerate II (to acetoacetate) [sulfur carrier] flavoprotein UTP D-isomer specific amino acid 1,4-alpha- ABC precorrin-8x (R)-pantothenate 2-C-methyl-D- in tRNA isomerase lysyl-D-alanyl-D-alanine) -acetylglucosamine) 5'-phosphate acyltransferase a sugar a sugar riboflavin kinase: ribF [corrinoid reductase: metF (R)-lipoate dehydrogenase: enolase: 2-hydroxyacid aspartate/ glucan transporter 5-formyltetrahydrofolate erythritol 2,4- protein: -N-acetylmuramyl- nudix family protein: a [co-chaperone]- adenosyltranferase] methylenetetrahydrofolate gapB eno propan-2-ol Electrotransfer glycerophosphoryl dehydrogenase tyrosine/aromatic branching of a sugar cyclo-ligase: KVU_1782 lipoate- Pantothenate cyclodiphosphate KVU_2173 succinate D-alanyl-D-alanine (pentapeptide) PII uridylyl- hydrolase, KVU_0109 peptidyl- [scaffold protein- FMN NAD salvage pathway I (PNC VI cycle) Cobalamin reductase: KVU_1754 ubiquinone diester FMN family protein: aminotransferase enzyme coproporphyrinogen III protein kinase: coaA synthase: ispDF phosphoenol dehydrogenase, carboxypeptidase: transferase: YffH glycerol-3- tRNA (2Fe-2S)] complex adenosyltransferase, a 5,10- a 5,10- 13-DPG mannose-6- (7Z)-hexadecenoyl-CoA oxidoreductase phosphodiesterase: adenylyltransferase / KVU_0372 protein: KVU_1260 (Alpha predicted FMN quinolinate ligase (R)-4'- 5-oxo-L-proline metabolism pyruvate glucose and glucose-1-phosphate degradation hydrophobic KVU_0432 peptidoglycan KVU_2584 family: trgB phosphate hydrolase: + methylmalonyl-CoA methylenetetrahydrofolate methenyltetrahydrofolate 2-C-methyl-D-erythritol- phosphate KVU_PB0185 aminotransferase, ABC hydrogenobyrinate adenylyltransferase / Coproporphyrinogen III NAD methylenetetrahydrofolate A: lplA acetone membrane anchor family protein: riboflavin kinase: ribF hydroxypyruvate pth amylase a sugar a sugar mutase cofactor phosphopantothenate 2,4-cyclodiphosphate isomerase- pyruvate α D-alanyl-D-alanine glycosyltransferase: UTP-GlnB classes I and acyltransferase transporter riboflavin kinase: ribF oxidase, aerobic: hemF dehydrogenase:methenyltetrahydrofolate KVU_1690 a [protein] with a [protein] with phosphoglycerate -D- protein: sdhD KVU_0126 glycerophosphoryl reductase protein: protein) Cobyrinic acid biosynthesis like kinase: carboxypeptidase: pbpA uridylyltransferase, II superfamily D-ribofuranose 1-oleoyl-snPlsY: KVU_0139 of a sugar a [chaperone-ATP]- NAD+ synthetase, cyclohydrolase: KVU_1690 (lipoyl)adenylate 4-hydroxy- an N-terminal an N-terminal kinase: pgk glucopyranose N-methylhydantoinase diester roseoflavin KVU_1085 : glgB ac-diamide protein: KVU_2125 protein: pmi pykA 1-phosphate (2E,7Z)- B/acetone dacC GlnD: glnD protein: tyrB 5-phosphate -glycerol 3- [co-chaperone]- FAD protoporphyrinogen IX glutamine 10 3-methylbut- L-glutamine L-glutamate 6 an oxidized phosphodiesterase adenine AMP Cys adenosylcob(III) an N - 3-phospho- 2-methylsulfanyl-N - H + ubiquinol-6 mono-trans,octa- a peptidoglycan hydroxypyruvate an aromatic cys a tRNA starch [scaffold protein- synthase: dependent: nadE NaMN thiazole biosynthesis II (aerobic bacteria) lipoate- 2-en-1-yl F6P hexadecenoyl-CoA carboxylase subunit electron-transfer protein: glpQ phosphate predicted NAD synthase alamin-[corrinoid formyltetrahydrofolate D-glycerate pyruvate 5'-deoxyadenosine dimethylallyladenosine 37 an unsulfurated cis-decaprenyl dinucleotide 2-oxo-acid (2Fe-2S)] complex KVU_PA0047 protoporphyrinogen protein molybdenum cofactor biosynthesis alpha: KVU_PB0142 met flavoprotein N-acetyl-muramoyl-(L- dimer ABC family protein: nadE adenosyltranferase] diphosphate phosphoglycerate in tRNA [sulfur carrier] diphosphate a uridylylated a sugar a sugar hydrogenobyrinate thioredoxin oxidase: hemG Nicotinate-nucleotide D-glyceraldehyde ligase phosphoglucomutase- alanyl-γ-D-glutamyl- D-ala (mycobacteria) transporter nicotinate adenine dinucleotide NMN synthase: mutase, 2,3- PII protein a,c-diamide pathway adenylyltransferase: Cobalamin 3-phosphate gly A: lplA a [protein] with 1: pgm acetoacetate L-lysyl-D-alanine) ethanolamine sn-glycerol of a sugar molybdate KVU_0697 γ bisphosphoglycerate- D-glucopyranose thiamine diphosphate protoporphyrin IX nadD adenosyltransferase, 1-deoxy-D- oxidoreductase, a [glycine- an N-terminal 5- -L-glutamyl [+ 2 isozymes] glucokinase: (S)-3-hydroxy-(7Z) 3-phosphate aerobic an oxidized 4-hydroxy- glutathione independent: gpmI a [chaperone- biosynthesis III Nicotinate-nucleotide nicotinate adenine methylmalonyl-CoA xylulose-5- DNA-bindingFAD-binding thiamine diphosphate cleavage complex ABC oxo-L-proline 5-phosphate glk L-sorbosone -hexadecenoyl-CoA predicted cobaltochelatase: thioredoxin 6 3-methylbut- an [2Fe-2S] ADP]-[disordered- (Staphylococcus) adenylyltransferase: dinucleotide mutase cofactor phosphate transcriptionalprotein: biosynthesis I (E. coli) H protein] N - molybdate 2-phospho- dehydrogenase: NAD-binding 3- ABC cluster protein cobS cobT 2-(2-carboxy-4- ferrochelatase: hemH nadD biosynthesis KVU_2544 lipoyl-L-lysine 2-en-1-yl di-trans,octa-cis UDP-N-acetyl- a ring-opened 7- an N-formyl-L- a peptidoglycan a 1-acyl-2- a peptidyl- a sugar a sugar activator 3HPP- 2-[(2R,5Z)- D-glycerate D-glucopyranose hydroxyacyl-CoA + ADP-α-D-glucose β-citryl-L- transporter form scaffold cob(II)yrinate methylthiazol-5- NAD+ synthase transporter, diphosphate gdhB -undecaprenyl α-D-muramoyl- methionylaminoacyl- H hydrogencarbonate dimer (E. faeciums) a peptide arachidonoyl- (R)-glycerate hippurate dipeptidase cyclohexanone NAD protein: KVU_2125 binding protein: 2-carboxy-4- 6-phosphate dehydrogenase: methylguanine in DNA glutamate of a sugar protein] complex a,c-diamide yl)ethyl phosphate Thioredoxin synthetase, 2: dxs inner synthase: ispG enolase: membrane-bound phosphate L-alanyl-γ-D- tRNA phosphatidylcholine hydroxypyruvate Dcp substrate alpha/beta Thiamine-phosphate protoheme NaMN nicotinamide synthase KVU_0202 methylthiazol-5(2H molybdopterin KVU_1278 reductase glutamine adenosylcobalamin 1-deoxy-D-xylulose membrane (E)-4-hydroxy-3- eno PQQ-dependent glutamyl-meso-2,6- reductase protein: hydrolase pyrophosphorylase: isochorismatase family 2-iminoacetate )-ylidene]ethyl a [lipoyl-carrier 5-oxo-L-proline D-alanyl-D-alanine nudix a sugar KVU_0489 a sugar protein: dependent: 5-phosphate [+ 2 isozymes] HMP-PP subunit: methylbut-2-en- phosphoenol dehydrogenase, 3-oxo-(7Z)- glycosyl diaminopimeloyl- Formamidopyrimidine- transcriptional KVU_1085 Amidohydrolase fold-3 thiE hydrolase: pncA protein: nadE 6 4-hydroxy- peptide carboxypeptidase: Xaa-Pro hydrolase, peptidyl- Hydrolase, thiamine KVU_0207 nadE phosphate protein]-N - KVU_0233 5-oxoprolinase: glucose/quinate/ hexadecenoyl-CoA transferase, DNA glycosylase: rpsT regulator phospholipase subfamily: an [Fe-S cluster cys 1-yl diphosphate 3-methylbut- pyruvate D-alanyl-D-alanine deformylase: KVU_0432 aminopeptidase: D-isomer specific YffH dipeptidase: putative: domain- phosphate FAD/NAD(P) nicotinate lipoyl-L-lysine [+ 3 isozymes] hyuB shikimate family family 4: mraY DNA protein, LysR D: KVU_PB0001 KVU_PB0041 biosynthesis menaquinol-7 biosynthesis NAD + Thiamine-phosphate molybdopterin 2-enyl pyruvate KVU_0171 KVU_0969 2-hydroxyacid family: trgB dcp KVU_PA0087 containing phosphoribosyltransferase: family protein: D-alanyl-D-alanine 2+ 2+ chaperone]-ATP -binding prenylated FMNH DNA-binding adenine [+ 10 isozymes] kinase: protein: gcd glycosylase: dehydrogenase [+ 4 isozymes] protein: Ni PB0039 Ni 2 pyrophosphorylase: molybdate diphosphate peptide carboxypeptidase: aminopeptidase all-trans- thioredoxin biosynthesis KVU_2339 glutathione-peroxide 2-[(2R,5Z)-2-carboxy- mutM KVU_PA0259 a 1-acyl-2- KVU_2034 nicotinate lipoate transcriptional a ThiS sulfur- thiE dinucleotide reductase: pykA D-glucono- undecaprenyldiphospho- UMP deformylase: dacC P: KVU_1215 family protein: α-D- predicted heptaprenyl 1,4-dihydroxy- reductase: lipoate redox reactions 4-methylthiazol-5(2H)- glu (5Z)-tetradecenoyl-CoA [+ 3 isozymes] arachidonoyl- choline a dipeptide citrate biosynthesis and activator 3HPP- carrier protein ispH 1,5-lactone N-acetylmuramoyl-L- def KVU_0372 glucopyranose benzoate a peptide glu ε-caprolactone ABC diphosphate 2-naphthoate thiamine trxB salvage I ylidene]ethyl phosphate pyruvate 2,6-diamino-4- sn-glycerol AMP gly thiamine thiamine DMAPP incorporation II binding protein: thiamine folate polyglutamylation 4-hydroxy- IPP SMP-30/ alanyl-γ-D-glutamyl-meso an apurinic site hydroxypyruvate 1-phosphate nitrate KVU_0523 nitrate transporter GSSG KVU_0202 3-methylbut- hydroxy-5-(N-methyl) within DNA a peptidoglycan a proteinogenic 3-phosphate of thiamine di-trans,poly-cis Thiamine octanoate phosphate Gluconolaconase/ -2,6-diaminopimeloyl- CO H O tetramer with a D-ala a peptide glutathione (R)-lipoate MoO - formamidopyrimidine 2 2 [+ 2 isozymes] 2 2-enyl D-lactate D-alanyl-D-alanine formate a L-methionylaminoacyl- amino acid -undecaprenyl pyrophosphokinase: a reduced nudix lipoate- lipoate- glutathione- LRE-like protein D,D cross-link prenol biosynthesis an [L-cysteine 2-(2-carboxy-4- a carboxy- a tetrahydrofolate molybdopterin diphosphate isopentenyl- dehydrogenase (2E,5Z)- tRNA a monocarboxylate PB0215 a monocarboxylatephosphate biosynthesis thiN thioredoxin hydrolase, NAD protein protein glutaredoxin N-end rule pathway I (prokaryotic) region family (Enterococcus demethylmenaquinol-7 pyridine desulfurase]-S- methylthiazol-5- adenylated-[ThiS cofactor reductase: diphosphate membrane- tetradecenoyl-CoA D-ribose KVU_2595 D-ribose (2E,6E)-farnesyl thiamine YffH phosphorylation and ligase ligase redox reactions protein: KVU_0536 faecium) cys glu nucleotide- sulfanyl-L-cysteine yl)ethyl phosphate sulfur-carrier protein] ispH delta- Leucyl/ (S)-lactate binding diphosphate diphosphate family: trgB transhydrogenation A: lplA A: lplA thiamine bifunctional [+ 2 isozymes] Undecaprenyl ubiquinone/ a [lipoyl-carrier disulfide glutathione isomerase, phenylalanyl- protein: dld NAD + 6 (lipoyl)adenylate diphosphate folylpolyglutamate 2+ 2+ pyrophosphate menaquinone protein] N - a carboxy- N-acetyl-β-D-glucosamine- 2605 Mg KVU_1783 Mg oxidoreductase 10 type 1: tRNA--protein D-gluconate an N-terminal uridine + dCTP β D-ribose KVU_0487 D-ribose thiamine diphosphate inorganic octanoyl-L-lysine synthase/ an N - a 5,10- an L-phenylalanyl- a 5-L-glutamyl- all-trans-retinyl palmitate a carboxypeptidase H O FAD NADH H anserine -citryl-L- synthetase biosynthesis dimerization KVU_0071 an amino acid adenylated- cys 1,6-anhydro-N- 2 a protein prenyl phosphate polyphosphate/ATP- lipoate- dihydrofolate formyltetrahydrofolate methylenetetrahydrofolate transferase: (3E,5Z)-tetradeca- (S)-3-hydroxy-(5Z) arginyl-[protein] [tRNA Phe ] [peptide] Taq substrate GTP in 23S rRNA Deoxycytidine glutamine di-trans,octa-cis1: uppS methyltransferase biosynthesis II (Bacillus) protein: gor lipoate biosynthesis a reduced a [protein] (R)-lactate [ThiS sulfur- acetyl-β-D-muramate ribosomal NAD kinase: ppnK protein menaquinol-6 acyl carrier synthase: folC an N-terminal aat 3,5-dienoyl-CoA -tetradecenoyl-CoA triphosphate carboxyl- -undecaprenyl ubiE: ubiE 2-(2-carboxy-4- γ-L-glutamyl- and incorporation I bifunctional bifunctional glutaredoxin N-terminal L- carrier protein] large subunit NADP + ligase biosynthesis protein arginyl-[protein] NAD-binding 3- alpha/beta FAD/NAD(P) succinyl- deaminase: terminal spermidine PB0186 spermidine diphosphate [+ 2 isozymes] methylthiazol-5- L-cysteine a [lipoyl-carrier folylpolyglutamate folylpolyglutamate DMAPP leucyl-L-arginine Leucyl/ gamma- carboxypeptidase pseudouridine Hydrolase, D-ribose KVU_0488 D-ribose A: lplA activation hydroxyacyl-CoA hydrolase fold-3 glycoside GTPase: -binding diaminopimelate KVU_2548 protease Undecaprenyl- yl)ethyl phosphateThiamine-phosphate NAD(P)+ protein]-N 6 -[(R) a [lipoyl-carrier an octanoyl-[acp] demethylmenaquinol-6 a tetrahydrofolate synthase/ synthase/ glutaredoxin: Amino Acid Degradation phenylalanyl- glutamyltransferase Taq (M32) synthase B: rluB putative: glutathione glutathione dehydrogenase: class V domain-containing hydrolase engA thioredoxin desuccinylase family diphosphatase menaquinol-7 pyrophosphorylase: -dihydrolipoyl]- 6 an apo acyl- dihydrofolate dihydrofolate grxC (3E,5Z)- tRNA--protein 2''-deoxycytidine prenylated FMNH synthetase transhydrogenase: protein]-N - lipoyltransferase: ubiquinone/ Leucyl/ KVU_1278 1: ggt aminotransferase: family 3 domain- metallopeptidase [+ 8 isozymes] ribosomal reductase: protein: dapE1 KVU_PA0087 protein: iron(III) dicitrate iron(III) dicitrate 1: uppP thiE 2 L-lysine carrier protein synthase: folC synthase: folC a protein with tetradecadienoate transferase: protein: KVU_1462 5''-triphosphate di-trans,octa-cis NADP thiamine protein: gshB pntB pntA lipoyl-L-lysine KVU_1974 menaquinone acyl carrier phenylalanyl- L-valine degradation I 3-oxo-(5Z)- [+ 4 isozymes] nifS containing superfamily large subunit trxB ctpA D-ribose KVU_0573 D-ribose 10 reduced L- L-proline degradation carboxylesterase, deaminase: iron(III)-enterobactin complex PA0233 iron(III)-enterobactin complex biosynthesis a [lipoyl-carrier protein] biosynthesis protein an N - a 5,10- tRNA--protein L-histidine L-citrulline degradation L-glutamate aat protein: protein: cxp pseudouridine -undecaprenyl phosphate 6 tetradecenoyl-CoA [+ 2 isozymes] + a peptide iron(III)-coprogen iron(III)-coprogen glutathione NADPH N -octanoyl-L-lysine cysteine residues degradation II degradation II type B: KVU_PB0164 H π KVU_0871 methyltransferase synthase formyltetrahydrofolate methylenetetrahydrofolate transferase: an α-(5-L- KVU_0011 phosphate synthase D: rluD N -methyl- citrate gln phosphate menaquinol-8 biosynthesis GDP 2605 β-alanine NAD + aat a [protein] val L-phenylalanyl-L- a pseudouridine dUTP menaquinol-9 biosynthesis ubiE: ubiE AcpS: acpS an N-terminal pro glutamyl)- a peptide [+ 2 isozymes] FADH NAD + L-histidine a holo acyl- N-terminal L- Phe 2 D-ribose KVU_0388 D-ribose inorganic S-adenosyl- his L-citrulline glu arginyl-[protein] a tRNA a thiocarboxy- a proteinogenic in 23S rRNA achromobactin KVU_0766 achromobactin thiamine salvage III [+ 2 isozymes] carrier protein L-lysyl-[protein] leucyl-L-lysine proline amino acid ala all-trans-retinol palmitate a peptide polyphosphate/ L-methionine a [lipoyl-carrier menaquinol-6 demethylmenaquinol-8 branched-chain Ornithine aspartate (3Z)-dodec- AMP [ThiS-Protein] amino acid demethylmenaquinol-9 thiamine dehydrogenase ATP-NAD 6 S-adenosylmethionine: carbamoyltransferase aminotransferase 1,6-anhydro-N- diphosphate biosynthesis protein]-N -[(R)- amino acid family protein: putA 3-enoyl-CoA GlcNAc Demethylmenaquinone thiamine protein: argF (S)-1-pyrroline- acetyl-β-muramate 3+ 3+ kinase: ppnK dihydrolipoyl]-L-lysine 2-demethylmenaquinone aminotransferase: urocanate carbamoyl protein: KVU_0981 Fe KVU_1363 Fe methyltransferase + Thiamine chromate KVU_0832 chromate NADP met methyltransferase mscL phosphate 5-carboxylate [+ 4 isozymes] protein: KVU_PA0089 pyrophosphokinase: protein: menG queuosine biosynthesis S-adenosylmethionine [+ 2 isozymes] asp a mature Demethylmenaquinone thiN II (queuine salvage) carbamoyl (2E)-dodec- an N-terminal an L-phenylalanyl- a [protein]- CTP synthetase 2: metK thiamine [+ 4 isozymes] 2-methylbutanoate methyl (indol-3-yl)acetate an all-trans-retinyl ester a carboxylic ester serotonin sarcosine carnosine sec a hydroxamate a hydroxamate 3-methyl-2- L-lysyl-[protein] Phe peptidoglycan L-glutamine ser a tRNA PA0235 methyltransferase: menG menaquinol-8 phosphate 2-enoyl-CoA [tRNA ] (n) ATP Deoxycytidine dGDP 3+ 3+ phe phe SAM diphosphate oxobutanoate aspartate ammonia- (meso-DAP RNA Fe Fe menaquinol-9 queuine 4-imidazolone- synthetase, L-glutamate-5- triphosphate val val lyase protein: aspA containing) ribonucleoside- PB0197 queuine tRNA- branched-chain 5-propanoate glutamine semialdehyde acetate-CoA deaminase: leu leu Leucyl/ carboxylesterase, carboxylesterase, carboxylesterase, transglutaminase succinyl- diphosphate ribosyltransferase: tgt alpha-keto acid amidotransferase ligase, AMP- type B: KVU_PB0164 type B: KVU_PB0164 type B: KVU_PB0164 oxidoreductase, diaminopimelate KVU_2548 seryl-tRNA reductase class ile ile a queuosine 34 proline fumarate phenylalanyl- protein: KVU_1191 tRNA- Fe 3+ PA0132 Fe 3+ dehydrogenase small subunit: carA L-glutamine (S)-3- dependent: lytic FAD-binding synthetase: in tRNA dehydrogenase tRNA--protein alpha/beta alpha/beta alpha/beta nucleotidyltransferase desuccinylase 2''-deoxycytidine Ib glutaredoxin: E2 subunit: degradation II hydroxydodecanoyl-CoA KVU_1477 transglycosylase: protein: serS carbamate family protein: putA transferase: hydrolase fold-3 hydrolase fold-3 hydrolase fold-3 1: KVU_2231 protein: dapE1 5''-triphosphate nrdH nrdE nrdF a tricarboxylate PA0192 a tricarboxylate KVU_0648 N-formimino- NAD-binding 3- KVU_0594 a [protein] N 6 - KVU_2544 L-glutamate aat domain-containing domain-containing domain-containing deaminase: GDP vibriobactin vibriobactin glu gln hydroxyacyl-CoA protein: KVU_1462 protein: KVU_1462 [+ 6 isozymes] protein: KVU_1462 [(5-hydroxy-1H- KVU_0871 KVU_0765 isobutanoyl-CoA 2-methylbutanoyl- an L-seryl- Fe 3+ Fe 3+ superpathway of L- Amino Acid Biosynthesis L-glutamine glutamate synthase dehydrogenase: diphosphate indol-3-yl)ethyl]- β sec L-histidine biosynthesis L-arginine biosynthesis I (via L-ornithine) superpathway of L-methionine biosynthesis (transsulfuration) L-phenylalanyl- CoA AMP RNA glyoxylate methylamine -alanine his UTP [tRNA ] isoleucine biosynthesis I superpathway of L-lysine, L-threonine and L-methionine biosynthesis I L-glutamate degradation I (Beta subunit): gltD KVU_1278 Phe a mature GlcNAc-1,6- L-glutamine a tricarboxylate PA0134 a tricarboxylate L-lysyl-[protein] a tRNA biosynthesis III CO glutamate synthase (indol-3-yl)acetate MeOH all-trans-retinol a fatty acid peptidoglycan anhMurNAc- an alcohol a carboxylate 2 3-oxododecanoyl-CoA (n) oxaloacetate PRPP oxaloacetate N-formyl- gln large subunit: gltB (meso-DAP L-Ala-γ-D-Glu- Fe 3+ PB0047 Fe 3+ oxaloacetate ATP glu TCA cycle aspartate 2-oxoglutarate TCA cycle I (prokaryotic) methylacrylyl-CoA L-glutamate aspartyl/ glu containing) DAP-D-Ala a tricarboxylate PB0050 a tricarboxylate aspartate aminotransferase glutamate synthase aminotransferase aspartate bifunctional N-formylglutamate glutamyl-tRNA protein: KVU_0981 large subunit: gltB protein: KVU_0981 aminotransferase acetyl-CoA amidotransferase: 3+ 3+ ornithine [+ 4 isozymes] amidohydrolase: a [DNA]-3'- a 5'-phospho- Nα,Nε-diacetyl-lysyl- an N-terminal- an N-terminal- Fe PB0048 Fe [+ 4 isozymes] protein: KVU_0981 ATP glutamate synthase a lipid II a peptidoglycan NAD + an oxidized c- (R)-lactate methylsalicylate sn-glycerol chitin a β-lactam acetyltransferase/ KVU_1896 L-phenylalanine pepN gatB decanoyl-CoA hydroxyl [DNA] glu a (6S)-5- L-methionyl-L- L-methionyl-L- a quaternary a quaternary [+ 4 isozymes] phosphoribosyltransferase (Beta subunit): gltD type cytochrome D-alanyl-D-alanine GDP α-D-mannose 3-phosphate dADP PB0152 asp N-acetylglutamate oxaloacetate (S)-3-hydroxy- Hydrolase, degradation II (anaerobic) [+ 11 isozymes] formyltetrahydrofolate threonyl-[protein] alanyl-[protein] acyltransferase beta- amine amine catalytic subunit: hisG asp glu 1-phosphate ribonucleoside- synthase: mutT isobutanoyl-CoA putative: glu L-aspartate family protein: polysaccharide lactamase asp histidyl-tRNA glycosyltransferase, NAD- D-alanyl-D-alanine carboxylesterase, diphosphate heme b KVU_1006 heme b aspartokinase: bifunctional Citrate synthase I: gltA KVU_PA0087 degradation I oxidoreductase, bifunctional methionine methionine KVU_0109 deacetylase domain- synthetase,-like phe family 51: mrcB dependent carboxypeptidase: type B: KVU_PB0164 reductase class KVU_2518 ornithine aspartokinase: KVU_2518 FAD-binding folylpolyglutamate aminopeptidase, mannose-1-phosphate aminopeptidase, family protein: containing a quaternary a quaternary protein: hisZ aspartate L-arginine (2E)-dec-2-enoyl-CoA peptidoglycan DNA KVU_0432 glycerol-3- Ib glutaredoxin: PA0132 aspartokinase: acetyltransferase/ glu asp protein: synthase/ alpha/beta type I: map2 guanylyltransferase: type I: map2 KVU_0493 protein: amine amine (S)-3-hydroxy- aminotransferase degradation glycosyltransferase: ligase: ligA phosphate nrdH nrdE nrdF L-aspartyl- KVU_2518 N-acetylglutamate Malate/L-lactate aspartate KVU_0317 dihydrofolate D-alanyl-D-alanine hydrolase fold-3 xanB KVU_1379 heme b KVU_0864 heme b L-aspartyl-4-phosphate isobutanoate protein: KVU_0981 III (arginine pbpA carboxypeptidase: domain-containing acyltransferase ADP 4-phosphate 1-(5-phospho-β-D-ribosyl)-ATP synthase: argJ dehydrogenase family L-asparagine aminotransferase synthase: folC PlsY: KVU_0139 [+ 6 isozymes] 6-phosphogluconate 3-phenyl-2-[+ 5 isozymes] decarboxylase/ dacC protein: KVU_1462 an N-terminal L- α an N-terminal L- 1-arachidinoyl- a substituted a polar a polar L-aspartyl-4-phosphate protein: KVU_PB0044 degradation I protein: KVU_0981 [DNA] NMN met GDP- -D- met acetate chitosan KVU_0297 aspartate- phosphoribosyl-ATP N-acetyl-L- aspartate-semialdehyde (S)-malate citrate dehydrogenase: oxopropanoate agmatinase (S)-3- di-trans,octa-cis threonyl-[protein] alanyl-[protein] sn-glycerol β-amino acid amino acid amino acid malate dehydrogenase [+ 4 isozymes] a peptidoglycan AMP a reduced c- pyruvate mannose glycine glycine semialdehyde pyrophosphatase: glutamate dehydrogenase, USG- mmsB pathway)arg hydroxydecanoyl-CoA -undecaprenyl a (6S)-5- 3-phosphate PB0152 aspartate- (NAD): mdh asn oxaloacetate type cytochrome Nα,Nε-diacetyl- betaine betaine dehydrogenase, hisE 1 related protein: asd (S)-methylmalonate- NAD-binding 3- diphosphate formyltetrahydrofolate D-ala salicylate MeOH USG-1 related semialdehyde acetylglutamate cytoplasmic lysyl-D-alanine semialdehyde asparaginase hydroxyacyl-CoA a polar a polar protein: asd dehydrogenase, 1-(5-phospho-β-D-ribosyl)-AMP kinase: argB L-aspartate 4-semialdehyde aconitate hydratase PB0053 phenylacetaldehyde agmatine I: ansA dehydrogenase: glycine glycine amino acid amino acid USG-1 related 1: KVU_0869 PA0120 L-aspartate 4- phosphoribosyl- N-acetylglutamyl- methylmalonate- KVU_1278 DNA with adenine:7,8- an N-terminal- an N-terminal- betaine betaine protein: asd Homoserine hydrolase L-asparaginase GlcNAc-1,6- RNase III mRNA an [amino group carrier a peptidoglycan a dietary all- lysine within RNase G semialdehyde AMP cyclohydrolase phosphate semialdehyde phenylacetaldehyde II: ansA1 pyruvate anhMurNAc-L-Ala- processing protein]-C-terminal-γ- dimer (S. aureus) dihydro-8- (R)-lipoate L-methionyl-L- L-methionyl- degradation thr a phenyl acetate L-aspartate 4- dehydrogenase, NAD dehydrogenase dehydrogenase: ald arginase 3-oxodecanoyl-CoA trans-retinyl ester gcv protein H an (aminoalkyl)phosphonate an (aminoalkyl)phosphonateHomoserine domain protein: hisI N-acetyl- binding domain family fumarate cis-aconitate (S)-3-amino-2- asp γ-D-Glu-DAP-D-Ala substrate (L-ornithyl)-L-glutamate oxoguanine mismatch seryl-[protein] glycyl-[protein] substrate mRNA PA0157 semialdehyde β (Acylating) family aspartate ribonuclease Threonine an alkylphosphonate an alkylphosphonate dehydrogenase, 1-(5-phospho- -D-ribosyl)- gamma- aconitate hydratase H + KVU_1977 H + protein: KVU_1984 methylpropanoate protein: iolA phenylacetate protein: pyruvate, carbamoyltransferase D-alanyl-D-alanine flagellar lipoate- E: rne dehydratase NAD binding 5-[(5-phosphoribosylamino) glutamyl- 1: KVU_0869 A/G-specific methionine methionine hydrolase: Dihydrodipicolinate speB phosphate murein ribonuclease catalytic subunit: argD carboxypeptidase: biosynthetic protein ribonuclease protein: ilvA domain family Homoserine methylideneamino]imidazole- phosphate L-homoserine superpathway of branched chain amino acid biosynthesis flavoprotein adenine aminopeptidase, aminopeptidase, KVU_0234 synthase family dikinase: hydrolase: lrgB III: KVU_2022 aminotransferase, KVU_0432 protein ligase A: lplA G and E- Threonine a polyamine PB0186 a polyamine protein: KVU_1984 dehydrogenase, 4-carboxamide reductase: subunit: KVU_2463 hydrogencarbonate putrescine octanoyl-CoA glycosylase: type I: map2 type I: map2 protein: dapA NAD binding 1-5- imidazole- superpathway of L-homoserine and L-methionine biosynthesis ppdK [+ 2 isozymes] ribonuclease classes I and D-alanyl-D-alanine FliP: fliP like protein: dehydratase NAD(P)+ argC pyruvate [+ 3 isozymes] III: rnc mutY H + H + L-homoserine dihydrodipicolinate domain family 4-carboxamide N-acetyl-L- Homoserine O- thr II superfamily carboxypeptidase: a [glycine-cleavage KVU_1612 protein: tdcB transhydrogenase β γ acetate a phenol synthase protein: KVU_1984 isomerase 1: hisA glutamate 5- succinyltransferase N-acetyl- -D- L-alanyl- -D- an [amino group protein:carrier KVU_2279 dacC complex H protein] an N-terminal an N-terminal an mRNA fragment 2-oxobutanoate biosynthetic type asp succinate D-threo-isocitrate phosphoenol + a polyamine KVU_0211 a polyamine Threonine diphosphate H glucosamine-1,6- glutamyl-meso-2,6- RNase III γ an apurinic site all-trans-retinol a fatty acid 6 met L-seryl-[protein] met glycyl-[protein] protein: dapA phosphoribulosylformimino- semialdehyde protein: metA acetolactate AMP pyruvate protein]-C-terminal- -(L- N -lipoyl-L-lysine dehydratase isocitrate anhydro-N-acetyl- diaminopimeloyl- an mRNA fragment processing + + AICAR-phosphate aspartate cys synthase: ilvH ilvB succinyl-CoA ligase GDP- (2E)-oct-2-enoyl-CoA glutamate 5-semialdehyde- a peptidoglycan adenine within DNA H KVU_1821 H protein: ilvA dehydrogenase: icd β-D-muramate D-alanine product mRNA (2S,4S)-4- L-homoserine carbamoyltransferase aspartokinase: KVU_2518 forming alpha-chain: sucD 2-yl)-L-glutamate with D,D cross- D-ala O-phospho- hydroxy-2,3,4,5- (S)-2-acetolactate a polyamine KVU_1114 a polyamine imidazole glycerol catalytic subunit: argD O-succinyl-L-homoserine Threonine ATP-dependent link (S. aureus) L-homoserine tetrahydrodipicolinate dehydratase phosphate synthase aminotransferase, GTP carboxylate-amine H + KVU_1767 H + Homoserine O- protein: tdcB L-aspartyl-4-phosphate Threonine subunit HisF: hisF classes I and cyclohydrolase ligase-like protein: sucC (S)-3- a [ribosomal (2-hydroxyphenyl)methyl 1-hydroxy- a dipeptide with a 4-methyl-5-(2- an N-terminal- a peptide with a [protein]-L- succinyltransferase hydrogencarbonate O-succinylhomoserine a sulfurated + a peptide with a a protein with incorrect ethanol synthetase II superfamily I: KVU_0509 hydroxyoctanoyl-CoA protein S12] A NADH H all-trans-retinyl palmitate phosphooxyethyl) L-methionyl-L- an N-terminal ω phenyl acetate a polysaccharide KVU_2450 a polysaccharide protein: metA (Thiol)-lyase protein: metZ (2Z)-2-aminobut-2-enoate aspartate-semialdehyde succinyl-CoA 2-oxoglutarate Aromatic Compound Degradation [sulfur carrier] 6-oxocyclohex-2-ene-1-carboxylate penultimate glycine C-terminal L-proline HMP-PP disulfide bonds proline ( = 180) protein: thrC (S)-2,3,4,5- O-phospho- protein: KVU_2279 NAD-binding 3- L-aspartate 89 thiazole thiol-disulfide valyl-[protein] L-methionine peptidyl-prolyl Catalase cys AICAR D-erythro-1-(imidazol-4- carbamoyl (2R)-2,3-dihydroxy- dehydrogenase, USG- Cu 2+ KVU_0561 Cu 2+ tetrahydrodipicolinate L-homoserine hydroxyacyl-CoA isomerase and cis-trans domain thr yl)-glycerol 3-phosphate phosphate N-acetyl-L- 3-methylbutanoate 1 related protein: asd chlorosalicylate degradation carboxylesterase, NADH dehydrogenase carboxylesterase, dipeptidase O-succinyl-L-homoserine L-cystathionine protocatechuate degradation dehydrogenase: Thiamine-phosphate thioredoxin: trx methionine methionine isomerase protein: katE hydrolase: 2,3,4,5- Threonine imidazoleglycerol- synthetase, ornithine dihydroxy-acid 4-sulfocatechol ribosomal protein S12 type B: KVU_PB0164 transmembrane carboxypeptidase: type B: KVU_PB0164 PepE: pepQ1 predicted II (ortho-cleavage pathway) KVU_1278 pyrophosphorylase: aminopeptidase, aminopeptidase, cyclophilin catalase/ KVU_0234 Threonine tetrahydropyridine- synthetase phosphate glutamine dehydratase: ilvD L-aspartate 4-semialdehyde degradation methylthiotransferase protein: ndhd KVU_1550 dithiol-disulfide ABC efflux 2-iminobutanoate dihydrolipoyllysine-residue 4-chlorosalicylate 5-chlorosalicylate alpha/beta hydrolase alpha/beta Xaa-Pro thiE type I: map2 type I: map2 type: zapE peroxidase Cu 2+ KVU_0930 Cu 2+ a polysaccharide a polysaccharide dehydratase 2,6-carboxylate N- protein: thrC dehydratase: hisB amidotransferase 3-oxooctanoyl-CoA rimO: KVU_2580 carboxypeptidase: isomerase: transporter of a O-succinylhomoserine L-cystathione β-lyase: metZ succinyltransferase, E2 protocatechuate 4-sulfocatechol fold-3 domain-containing NADH dehydrogenase hydrolase fold-3 aminopeptidase: [+ 8 isozymes] HPI: katA protein: ilvA succinyltransferase: small subunit: carA 3-methyl-2-oxobutanoate Homoserine KVU_1651 KVU_2315 polysaccharide (Thiol)-lyase thr 3-(imidazol-4-yl)-2- component of oxoglutarate Protocatechuate Protocatechuate protein: KVU_1462 subunit: KVU_1220 domain-containing KVU_0969 a protein with correct a [protein]-L- acetate phenol dapD dehydrogenase, NAD monooxygenase, monooxygenase, a [ribosomal an N-terminal ω acetaldehyde Threonine protein: metZ oxopropyl phosphate carbamoyl L-ornithine dehydrogenase: sucB 3,4-dioxygenase: 3,4-dioxygenase: 5'-deoxyadenosine an unsulfurated protein: KVU_1462 thiamine disulfide bonds proline ( = 0) N-succinyl-2-amino- binding domain family FAD-binding FAD-binding met protein S12]-3- met L-valyl-[protein] met a peptide Cu 2+ KVU_0496 Cu 2+ predicted dehydratase histidinol-phosphate phosphate L-homocysteine 2-aminoprop-2-enoate 2-isopropylmalate branched-chain pcaG pcaH pcaG pcaH [sulfur carrier] 1-hydroxy-6-oxocyclohex- a peptide with a phosphate 6-ketopimelate protein: KVU_1984 methylsulfanyl- + an amino acid a proteinogenic ABC efflux protein: tdcB synthase: amino acid 2-oxobutanoate protein: nahG protein: nahG 3-carboxy-cis,cis-muconate 3-sulfomuconate salicyl alcohol NAD A(H2) pro aminotransferase: hexanoyl-CoA L-aspartate 89 2-ene-1-carboxylate C-terminal glycine a polysaccharide a polysaccharide aminotransferase, L-cystathionine Ornithine KVU_1773 palmitate a retinol amino acid transporter of a (2Z)-2-aminobut- hisC methionine aminotransferase: biosynthetic type L-homoserine classes I and carbamoyltransferase methionine synthase, 3-carboxy- 3-sulfomuconate iron(III) iron(III) polysaccharide 2-enoate histidinol-phosphate synthase: KVU_1843 2-isopropylmalate mscL acetolactate PB0049 II superfamily protein: argF vitamin-B12 cis,cis-muconate cycloisomerase: dicitrate dicitrate aminotransferase: dihydropteroate synthase, 2-iminopropanoate synthase: leuA [+ 2 isozymes] synthase: ilvH ilvB protein: KVU_2279 L-cystathione independent: KVU_2213 cycloisomerase: pcaB pcaB glucosyl-(heptosyl) UDP-α-D-galactose quinoxaline-2- an N-terminal 3'-dephospho- N-acetyl-D- a dipetide with an N- a long-chain D-sedoheptulose a bile acid KVU_0101 a bile acid β KVU_1757 DHPS:Homocysteine S- Homoserine O- H O an L-arginyl- isoquinoline MeOH -lyase: metZ (S)-2-aceto-2- diphosphate 2 3-sulfino-L- (-)-methyl jasmonate galactosamine N-succinyl-L,L-2,6- 4-chlorocatechol (2-carboxy-2,5-dihydro- -Kdo -lipid A- aryl-carrier protein carboxyl adenylate Arg CoA terminal L-aspartate fatty aldehyde 1-phosphate asp [+ 2 isozymes] methyltransferase:Cobalamin- succinyltransferase 4-sulfomuconolactone trans-hex-2-enoyl-CoA 3 2 [tRNA ] ATP asp L-citrulline (2S)-2-isopropylmalate hydroxybutanoate Respiration 2-oxoglutarate decarboxylation to succinyl-CoA 5-oxofuran-2-yl)-acetate bisphosphate alanyl-[protein] 6-phosphate carbon monoxide Catalase a metal a metal 2-iminobutanoate diaminopimelate L-histidinol phosphate dependent methionine: metH val protein: metA aspartate KVU_0893 GTP 4-carboxymuconolactone dehydrogenase: domain cation cation 2+ 2+ succinyl- 2-aminoprop-2-enoate cys fructose- racemase Cd KVU_0530 Cd L-homocysteine cyclohydrolase a [2-oxoglutarate dehydrogenase dihydrolipoyllysine- inorganic carboxylesterase, dipeptidase iorB1 KVU_PA0250 Alkanal protein: katE diaminopimelate pyruvate decarboxylase lipopolysaccharide acyl carrier Arginine- N-acetylglucosamine- bisphosphate family Argininosuccinate met E2 protein] N 6 -lipoyl-L-lysine residue type B: KVU_PB0164 monooxygenase: desuccinylase I: KVU_0509 O-succinyl-L-homoserine (PcaC): pcaC 3-alpha- protein: pyrophosphatase, tRNA-protein Dephospho- 6-phosphate PepE: pepQ1 isoquinoline 1- catalase/ protein: methionine synthase succinyltransferase, 3-chloro-cis,cis-muconate methylsalicylate degradation (S)-3- alpha/beta KVU_PB0062 aldolase: fbaB a metal a metal protein: dapE1 methionine (R)-2,3-dihydroxy- (4,5-dihydro-5- 2-maleylacetate galactosyltransferase: KVU_1599 manganese- transferase: CoA kinase: deacetylase: nagA oxidoreductase peroxidase KVU_1335 KVU_1837 synthase: (ISS): argG 2-isopropylmaleate dihydrolipoamide E2 component hydroxyhexanoyl-CoA dependent: ppaC hydrolase fold-3 coaE [+ 3 isozymes] cation cation Co 2+ KVU_0533 Co 2+ 2-oxobutanoate synthase, histidinol 3-methylpentanoate oxofuran-2-yl)-acetate lpcA KVU_0682 alpha subunit: HPI: katA [+ 2 isozymes] KVU_1843 2-iminopropanoate O-succinylhomoserine dehydrogenase, of oxoglutarate 4-methylsalicylate 5-methylsalicylate NAD-binding 3- domain-containing a proteinogenic D-aspartate vitamin-B12 a quinoxaline-2- D-galactosamine asp KVU_2416 DHAP D-erythrose formaldehyde biosynthetic dihydropteroate synthase, histidinol L-arginino- dihydroxy-acid (Thiol)-lyase protein: metZ FAD/NAD(P)-binding, dehydrogenase: putative hydrolase hydroxyacyl-CoA protein: KVU_1462 amino acid isoquinolin- independent: galactosyl-glucosyl- carboxyl-[aryl- an N-terminal L- acetate 6-phosphate ν a long-chain type L,L-diaminopimelate DHPS:Homocysteine S- dehydrogenase succinate dehydratase: ilvD component of the sucB sucA or acyltransferase: dehydrogenase: UDP AMP H + coenzyme A H + 2(1H)-one h KVU_2213 (2R)-2-chloro-2,5-dihydro- monooxygenase, monooxygenase, (heptosyl) -Kdo - carrier protein] phosphate a tRNA Arg arginiyl-3-sulfino- fatty acid predicted 2-oxoglutarate pcaD KVU_1278 3 2 ADP hemin KVU_0917 hemin acetolactate methyltransferase:Cobalamin- 3: hisD argininosuccinate dihydrolipoyllysine- 5-oxofuran-2-acetate 3-oxoadipate ABC diaminopimelate [+ 2 isozymes] L-arginine biosynthesis II (acetyl cycle) (2R,3S)-3-isopropylmalate (S)-3-methyl-2-oxopentanoate L-cystathionine dehydrogenase: FAD-binding FAD-binding lipid A-bisphosphate L-alanyl-[protein] (-)-jasmonate MeOH a metal a metal synthase: dependent methionine: metH lyase: KVU_0151 residue 3-oxoadipate transporter epimerase: dapF pyruvate histidinal lpdA sucB protein: nahG protein: nahG 3-oxohexanoyl-CoA cation cation ilvH ilvB Argininosuccinate 3-isopropylmalate branched-chain succinyltransferase, salicylate of a metal [+ 3 isozymes] (S)-2-aceto-2- met lyase 2: asaL N-acetylglutamyl-phosphate dehydrogenase: amino acid E2 component degradation I cation predicted histidinol L-cystathione β-lyase: metZ a [2-oxoglutarate dehydrogenase an N-terminal hydroxybutanoate meso-diaminopimelate leuB aminotransferase: of oxoglutarate 4-methylcatechol an L-arginyl- ABC dehydrogenase a [2-oxoglutarate dehydrogenase E2 6 a single stranded DNA hydrogen cyanide a sulfurated glutathione 3-sulfo-L- acibenzolar-S-methyl γ-L-glutamyl-(S)- a phosphatidylcholine an adenine in DNA γ-L-glutamyl- (S)-malate E2 protein] N -S- 2-maleylacetate protoanemonin salicylate hypoglycin A Arg homocarnosine gly gly acyl-carrier protein lys a metal a metal a [FeS] iron- transporter a [FeS] iron- GTP 3: hisD arg (2S)-2-isopropyl- mscL protein] N 6 -dihydrolipoyl-L-lysine dehydrogenase: sucB [sulfur carrier] [tRNA ] 2-aminobutanoate D-alanine KVU_1738 succinyldihydrolipoyl-L-lysine monooxygenase, alanyl-[protein] Type I malonyl CoA- oxaloacetate- cation cation sulfur cluster of a [FeS] sulfur cluster cyclohydrolase diaminopimelate bifunctional ornithine 3-oxosuccinate [+ 2 isozymes] L-homocysteine 2-aminoprop-2-enoate butanoyl-CoA aminomutase, L-tyrosine FAD-binding restriction- acyl carrier decarboxylating iron-sulfur I: KVU_0509 decarboxylase: lysA his acetyltransferase/ ssDNA-specific carboxylesterase, putative kamA L-tryptophan biosynthesis biosynthesis I protein: nahG 3-mercaptopyruvate gamma- Arginine- succinyl- glutathione phospholipase modification glutathione protein malate cluster (R)-2,3-dihydroxy- N-acetylglutamate ile methionine exonuclease type B: KVU_PB0164 and yjeK- catechol sulfurtransferase: glutamyltransferase tRNA-protein diaminopimelate synthetase D: KVU_PB0001 system DNA synthetase transacylase dehydrogenase a metal a metal 3-methylpentanoate lys synthase: mutT N-acetyl-gamma- methionine synthase, synthase: KVU_1843 3-oxoadipate RecJ: recJ alpha/beta like protein: KVU_0084 ferrichrome PA0233 ferrichrome chorismate KVU_1838 1: ggt transferase: desuccinylase protein: gshB methylase, protein: gshB (MCT): fabD (NADP(+)): KVU_1996 cation cation dihydroxy-acid glutamyl-phosphate 4-methyl-2-oxopentanoate vitamin-B12 [+ 3 isozymes] hydrolase fold-3 gln chorismate bifunctional ornithine dihydropteroate synthase, 2-iminopropanoate crotonyl-CoA [+ 2 isozymes] KVU_0682 protein: dapE1 putative: hsdM KVU_PB0117 β reductase: argC independent: KVU_2213 pyruvate [+ 4 isozymes] domain-containing a 1,2-diacyl- a malonyl-[acp] L- -lysine dehydratase: mutase: acetyltransferase/ acetylglutamate DHPS:Homocysteine S- choline [+ 2 isozymes] pyruvate branched-chain dehydrogenase sn-glycerol 6 ilvD anthranilate synthase: trpE KVU_2428 L-phenylalanine N-acetylglutamate kinase: argB [+ 2 isozymes] methyltransferase:Cobalamin- a single-stranded protein: KVU_1462 ophthalmate an N -methyladenine norophthalmate a metal a metal Fe 3+ Fe 3+ amino acid complex, E2 component, a ribonucleoside thiocyanate an unsulfurated an N-terminal L- 3-phosphate KVU_0499 KVU_0262 (S)-3-methyl-2- glutamine amidotransferase: prephenate biosynthesis I synthase: argJ dependent methionine: metH Arg in DNA cation cation a Coα-[α-(5,6-dimethylbenzimidazolyl)]-cobamide a Coα-[α-(5,6-dimethylbenzimidazolyl)]-cobamide aminotransferase: dihydrolipoamide 5'-monophosphate oligodeoxyribonucleotide [sulfur carrier] hypoglycin B L-cysteinylglycine a tRNA arginiyl-3-sulfo- 4-aminobutanoate his oxopentanoate KVU_1203 glu N-acetyl-L-glutamate N-acetyl-L-glutamate 5-semialdehyde L-proline biosynthesis protein tyrC: aspartate mscL acetyltransferase: pdhB (S)-3- L-alanyl-[protein] acibenzolar MeOH branched-chain chorismate gln met pyruvate I (from L-glutamate) anthranilate Cyclohexadienyl carbamoyltransferase [+ 2 isozymes] hydroxybutanoyl-CoA amino acid chorismate dihydrolipoyllysine- a metal a metal an inorganic an inorganic dehydrogenase: bifunctional ornithine catalytic subunit: argD NAD-binding 3- KVU_0501 KVU_1340 aminotransferase: mutase: carbamoyl phosphate residue Amine and Polyamine Degradation cation cation anion anion glu anthranilate tyrC KVU_2428 acetyltransferase/ aminotransferase, leu hydroxyacyl-CoA UDP-N-acetyl- undecaprenyldiphospho- a thiocarboxylated cyclic a peptide with synthetase, glutamine Fatty Acid and Lipid Biosynthesis succinyltransferase, a 7,8-dihydro-8- an N-modified + (2R,3S)-2,3- a [protein]-L- mscL phosphoribosyltransferase: trpD 3-(4- dehydrogenase: α-D-glucosamine a proteinogenic leukotriene-C4 [SAMP] C- pyranopterin O-ureido-L- FMN NAD(P)H H leukotriene-D4 a holo [PedD acyl- 3',5'-ADP Gamma- prephenate L-serine biosynthesis I amidotransferase N-acetylglutamate classes I and E2 component N-acetylmuramoyl-L- oxoguanine in DNA an N-terminal aminoacyl-[tRNA] asp dimethylmalate methionine [+ 2 isozymes] hydroxyphenyl) glycine biosynthesis II superpathway of N-acetylglucosamine, KVU_1278 γ amino acid homoserine carrier protein] glutamyl synthase: mutT II superfamily of oxoglutarate aromatic biogenic amine degradation (bacteria) alanyl- -D-glutamyl-meso terminal glycine phosphate Xaa-L-proline malonyl CoA- methionine 3'(2'),5'- N-(5-phosphoribosyl)-anthranilate pyruvate prephenate small subunit: carA uracil degradation palmitate biosynthesis N-acetylmannosamine and N- creatinine degradation II Peptide PA0180 Peptide predicted kinase: 3-phospho- bifunctional ornithine protein: KVU_2279 a [glycine-cleavage anteiso-branched-chain fatty acid biosynthesis octanoyl-[acyl-carrier cyclopropane dehydrogenase: sucB -2,6-diaminopimeloyl- acyl carrier sulfoxide bisphosphate ile aminotransferase, dehydratase I (reductive) (type II fatty acid synthase) even iso-branched-chain fatty acid biosynthesis phosphatidylglycerol biotin-carboxyl carrier acetylneuraminate degradation acetoacetyl-CoA Formamidopyrimidine- FMN 2,3- dipeptidase ABC KVU_0963 D-glycerate carbamoyl phosphate L-ornithine acetyltransferase/ 6 protein] biosynthesis fatty acid (CFA) D-alanyl-D-alanine gamma- molybdopterin peptidyl- Argininosuccinate reductase A: nucleotidase: Fe 2+ Fe 2+ N-(5'-phosphoribosyl) complex H protein] N - biosynthesis I (plastidic) protein assembly tyramine DNA glycosylase: rpsT Xaa-Pro reductase: dimethylmalate AC: protein transporter classes I and domain NAD-binding D- uracil biosynthesis N-acetylneuraminate creatinine KVU_1622 KVU_2200 2+ 2+ glutamate N-acetylglutamate aminomethyldihydrolipoyl- (mitochondria, yeast) D-inositol-3-phosphate glutamyltransferase synthase aminopeptidase: tRNA synthase KVU_1212 lyase: prpB KVU_0070 transacylase Mn Mn anthranilate isomerase: trpF II superfamily protein: isomer specific an acetoacetyl-[acp] ile a [biotin a [phospholipid] cis dopamine DNA [+ 2 isozymes] Peptide KVU_0937 Peptide of Mn2+/ 5-kinase synthase: argJ L-lysine val DHAP glycosyltransferase: 1: ggt subunit KVU_0969 hydrolase: (ISS): argG (MCT): fabD a protein-L- 1-(2-carboxyphenylamino)-1- protein: tyrB KVU_0426 2-hydroxyacid glycine cleavage system an acetoacetyl-[acp] carboxyl-carrier -olefinic fatty acid amine glycosylase: a malonyl- AMP Fe2+ γ 1: proB N-acetyl-L-ornithine glycine cleavage system glycerol-3- cyclopropane- 2-oxoisovalerate decarboxylation to isobutanoyl-CoA N-acetyl-D- murG [+ 4 isozymes] MoaD: moaD [+ 3 isozymes] pth methionine- -L-glutamyl deoxy-D-ribulose 5-phosphate aspartate/ 3-phenyl-2- dehydrogenase: aminomethyltransferase short-chain short-chain protein]-L-lysine amine oxidase flavin- mutM [PedD acyl- 5,6-dihydrouracil aminomethyltransferase gly branched-chain phosphate biotin-- fatty-acyl- mannosamine N-methylhydantoin octopamine (R)-synephrine acetyl-CoA FMNH NAD(P) + propanoate pyruvate leukotriene-E4 (S)-S-oxide 5-phosphate serA T: gcvT dehydrogenase: branched-chain dehydrogenase: an [apo BCAA oxidase flavin- 2 gly carrier protein] Na + KVU_1699 Na + ammonia indole-3-glycerol phosphate tyrosine/aromatic oxopropanoate T: gcvT amino acid containing canavaninosuccinate KVU_2131 amino acid dehydrogenase: acetyl-CoA- phospholipid containing lipid II (meso α γ a [SAMP] C- a peptide with predicted assimilation cycle III Gamma- synthase protein: trpC aminotransferase aspartate [+ 2 isozymes] Hydantoinase glycine aminotransferase: KVU_2131 dehydrogenase N-methylhydantoinase protein: UDP an -( -L-glutamyl) molybdopterin 7,8-dihydro- an apurinic site a proteinogenic an N-modified an uncharged aminomethyl gpsA carboxylase synthase: cfa 6 leukotriene-D4 glutamyl protein: KVU_1260 3-phosphooxypyruvate Ornithine dehydrogenase: [+ 5 isozymes] aminotransferase: a (3R)-3-[+ 5 isozymes] sn-glycerol a [phospholipid] E2 protein] N branched-chain B (HuyB-1): huyB protein: KVU_PA0126 diaminopimelate containing) -L-amino acid terminal glycine an N-terminal amino acid tRNA ABC aminotransferase beta subunit- transferase mscL ligase: 8-oxoguanine within DNA amino acid Peptide Peptide phosphate carbamoyltransferase gcvP mscL hydroxybutanoyl- 3-phosphate fatty acid containing -lipoyl-L-lysine alpha-keto acid N-acetyl-D- [+ 10 isozymes] KVU_PA0126 L-proline transporter a long-chain a long-chain ammonium glu (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate protein: KVU_0981 phosphoserine like protein: family protein: a (3R)-3- [+ 2 isozymes] KVU_1809 cyclopropane mannosamine of a peptide KVU_0820 reductase tyr protein: argF a [glycine-cleavage a [glycine-cleavage [+ 2 isozymes] [acp] branched-chain dehydrogenase (4-hydroxyphenyl) N-acetylglucosamine fatty acid fatty acid [+ 5 isozymes] aminotransferase L-alanine KVU_PB0168 KVU_1762 6 hydroxybutanoyl-[acp] glycerol-3- a [biotin carboxyl- 3,4-dihydroxyphenylacetaldehyde GPR: proA complex H protein] N complex H protein] (S)-3-methyl-2-oxopentanoate beta- alpha-keto acid E2 subunit: 6-phosphate N-carbamoylsarcosine degradation II a mature peptidoglycan (meso an apo-[LYS2 L- a 1-acyl-2- β an insertion tryptophan [+ 3 isozymes] phosphate acetaldehyde + methyl -D-glucoside a supercoiled protein: serC biosynthesis III -dihydrolipoyl-L-lysine N 6 -lipoyl-L-lysine 3-methyl-2-oxobutanoate carrier protein]-N N-acetylmannosamine- a proteinogenic glutathione coenzyme A coenzyme A [EntF L-seryl- an L-arginyl- a RNA-DNA hybrid acetyl-CoA NADP FMNH a holo [PedN acyl- beta- hydroxyacyl- dehydrogenase KVU_0648 -diaminopimelate containing) 2-aminoadipyl- arachidonoyl- 2 sequence predicted glutamine L-glutamate-5- synthase: trpB trpA phe acyltransferase 6 -biotinyl-L-lysine 6-phosphate N-acetyl-D- a protein Arg 6-phosphate duplex DNA O-phospho- 3-ureidopropanoate hydroxyacyl- branched-chain (Acyl-carrier- E2 subunit: aldehyde amino acid carrier protein] [tRNA ] carrier protein] element IS30 ABC synthetase semialdehyde branched-chain PlsY: KVU_0139 epimerase: nanE glucosamine carrier-protein] sn-glycerol acetyl-coenzyme malonyl CoA- ATP- Peptide Peptide ser L-serine cys (Acyl-carrier- alpha-keto acid protein) KVU_0648 dehydrogenase N-acetylglucosamine CTP transporter family protein: indole alpha-keto acid N-acetyl-D- lytic transglycosylase: 3-phosphate A carboxylase acyl carrier transposase: dependent DNA-binding N-carbamoyl- protein) dehydrogenase dehydratase acyltransferase an [apo BCAA family protein: ald (4-hydroxyphenyl) kinase: KVU_2002 ribonuclease FMN glycosyl of a peptide KVU_0291 phosphoserine dehydrogenase E2 [+ 2 isozymes] an [apo BCAA dehydrogenase glucosamine N-acetyl-D- KVU_0594 gamma- acyl carrier acyl carrier Arginine- carboxyl transferase protein KVU_1412 DNA L-cysteine transcriptional beta-alanine dehydratase E2 subunit: FabA: fabA family protein: a [biotin carboxyl- dehydrogenase acetate H: gcvH reductase: hydrolase [+ 2 isozymes] phosphatase glycine cleavage system subunit: KVU_0648 E2 protein] N 6 -S-[2- 6-phosphate sarcosine aldehyde glucosamine [+ 6 isozymes] glutamyltransferase protein protein phosphatidate tRNA-protein subunit alpha / biotin transacylase an insertion helicase tryptophan biosynthesis I activator 3HPP- amidohydrolase FabA: fabA KVU_0648 KVU_0109 carrier-protein E2 protein] N 6 [+ 2 isozymes] KVU_1212 family 1: bglA predicted (S)-1-pyrroline- SerB: serB L-citrulline aminomethyltransferase beta- a 1-acyl-sn methylpropanoyl]dihydrolipoyl- N-acetylglucosamine- dehydrogenase 6-phosphate 1: ggt synthase synthase cytidylyltransferase: transferase: carboxylase: accC1 (MCT): fabD sequence IS30 RecQ: recQ synthase: trpB trpA glycine binding protein: protein: amaB isobutanoyl-CoA dimer]-N 6 - -dihydrolipoyl- a malonyl[PedN a single ABC 5-carboxylate T: gcvT beta- 2-methylbutanoyl-CoA hydroxyacyl- -glycerol 3- L-lysine 6-phosphate FAD dependent FAD dependent family protein: aldA N-acetylglucosamine- [+ 4 isozymes] AcpS: acpS AcpS: acpS cdsA KVU_0682 [+ 3 isozymes] with integrated Peptide Peptide ser biosynthesis IV ser KVU_0202 biotinyl-L-lysine L-lysine oxidoreductase: oxidoreductase: a mature peptidoglycan a mature peptidoglycan strand β-D-glucose acyl-carrier stranded DNA transporter gln Argininosuccinate β [+ 2 isozymes] hydroxyacyl- (Acyl-carrier- phosphate deacetylase: nagA 6-phosphate γ a nucleoside 5'- malonyl-CoA FMN NADPH H + MeOH transposon pyrroline-5- Serine O- [+ 2 isozymes] -alanine biotin with (L-alanyl- -D-glutamyl- (non-reducing terminus) a holo-[LYS2 L- DNA 6-phosphate protein] of a peptide trp synthase (ISS): argG (Acyl-carrier- protein) acyltransferase D-glucosamine KVU_PA0165 KVU_2024 (3,4-dihydroxyphenyl) deacetylase: nagA a holo-[EntF L- a CDP-1-acyl- monophosphate glutamate carboxylate acetyltransferase: thr ala carboxylase: meso-2,6-diaminopimeloyl- an α-(γ-L-glutamyl) 3',5'-ADP 2-aminoadipyl- 3',5'-ADP an N-terminal alanine racemization protein) dehydratase family protein: 6-phosphate acetate L-cysteinylglycine Arg reductase: cysE accC gly D-glucosamine D-alanine) tetrapeptide -L-amino acid carrier-protein] seryl-carrier protein] 2-arachidonoyl- a tRNA arginyl-[protein] synthase (Beta alanine L-arginino-succinate dehydratase FabZ: fabZ KVU_0144 Peptide KVU_1263 Peptide KVU_0477 O-acetyl-L-serine a 4-methyl-3-oxopentanoyl-[acp] branched-chain 6-phosphate glycerol subunit): gltD racemase FabZ: fabZ a (4S)-4-methyl-3- acyltransferase: acetyl- alpha-keto acid pyrroline-5- ala argininosuccinate a (2E)-but- biotin creatinine degradation I glutamate domain- oxohhexanoyl-[acp] KVU_0791 coenzyme A dehydrogenase carboxylate cysteine synthase containing alanine racemase lyase: KVU_0151 short-chain 2-enoyl-[acp] carboxylase: carboxylase α-D-glucosamine a nascent peptidoglycan a negatively a supercoiled synthase large a (2E)-but-2-enoyl-[acp] short-chain a 1,2-diacyl- E2 subunit: an apo [peptidyl- an apo-[aryl- [EntB aryl- a [protein] N-terminal- + a holo [BryP acyl- domain-containing Argininosuccinate dehydrogenase: accC Glycolysis α coenzyme A coenzyme A coenzyme A arbutin-6-phosphate tributyrin FMN NADH H an alk-2-enal Peptide KVU_0984 Peptide subunit: gltB reductase: A: KVU_1110 protein: dehydrogenase: alcohol sn-glycerol carboxyl 6-phosphate creatinine -D-glucosamine (meso-DAP containing) formyl-L-methionine GTP supercoiled DNA duplex DNA protein: KVU_0553 lyase 2: asaL KVU_2131 KVU_0648 carrier protein] carrier protein] carrier protein] DNA carrier protein] Replicative Serine proC KVU_0190 enoyl-ACP KVU_2131 dehydrogenase 3-phosphate [+ 2 isozymes] transferase Creatinine 6-phosphate malonyl CoA- cys gly [+ 9 isozymes] reductase: [+ 5 isozymes] subunit topoisomerase DNA protease glu Metabolic Regulator Biosynthesis [+ 5 isozymes] GroES-like phosphatidate glycolysis III (from glucose) amidohydrolase: lytic transglycosylase: peptide glycosyl flagellar FMN acyl carrier pro D-ala arg fabI-3 alpha / biotin acyl carrier acyl carrier acyl carrier I: topA helicase, DO-like Peptide KVU_0429 Peptide a (3R)-3-hydroxy-4- protein: mecR cytidylyltransferase: KVU_0567 KVU_0594 deformylase: hydrolase biosynthetic reductase: protein a (4S,3R)-3-hydroxy- carboxylase: F6P protein protein protein GTP DNA DnaB: dnaB protein: methylpentanoyl-[acp] [+ 2 isozymes] cdsA D-glucopyranose [+ 3 isozymes] [+ 6 isozymes] KVU_0171 family 1: bglA protein FliP: fliP KVU_1212 transacylase ppGpp metabolism a butanoyl-[acp] 4-methylhexanoyl-[acp] accC1 synthase synthase synthase cyclohydrolase topoisomerase [+ 4 isozymes] KVU_0360 trehalose a CDP- creatine F6P a malonyl-(MCT): fabD a single beta-hydroxyacyl- a [carboxyl-carrier AcpS: acpS AcpS: acpS AcpS: acpS peptide I: KVU_0509 2+ 2+ biosynthesis V beta-hydroxyacyl- a butanoyl-[acp] diacylglycerol glucokinase: a mature peptidoglycan a nascent peptidoglycan IV subunit A: parC [BryP acyl- a 1-alkanal Ni Ni 3-oxoacyl- (Acyl-carrier-protein) protein dimer]-N 6 deformylase: def β-D-glucose stranded DNA KVU_0938 pppGpp (Acyl-carrier- glk with (L-alanyl-γ-D-glutamyl- (meso-DAP containing) hydroquinone a relaxed DNA butanoate 1,2-dibutyrin FMNH NAD + carrier protein] Peptide Peptide ACP dehydratase CDP-diacylglycerol-- 6-phosphate 2 Guanosine-3',5'- a glycogen protein) 3-oxoacyl- -carboxybiotinyl- a holo [peptidyl- a holo-[aryl- a holo-[EntB aryl- 7,8- synthase: fabB FabA: fabA glycerol-3-phosphate 3- D-glucopyranose urea meso-2,6-diaminopimeloyl- with GlcNAc terminus 3',5'-ADP 3',5'-ADP 3',5'-ADP formate bis(Diphosphate) 3'- dehydratase ACP L-lysine carrier protein] carrier protein] carrier protein] an N-terminal L- dihydroneopterin [+ 3 isozymes] phosphatidyltransferase: 6-phosphate degradation II D-alanine) tetrapeptide formate lipid IV biosynthesis (P. putida) Cell Structure Biosynthesis pyrophosphohydrolase: guanosine 3'-diphosphate FabA: fabA beta-hydroxyacyl- synthase: methionyl-[protein] 3'-triphosphate Ni 2+ Ni 2+ A lipid IV biosynthesis (E. coli) pgsA glucose-6- sarcosine KVU_0564 A peptidoglycan maturation (meso-diaminopimelate containing) KVU_0163 a maltodextrin (Acyl-carrier-protein) fabB Polymeric Compound Degradation Peptide Peptide 5'-triphosphate 3'- a 3-oxohexanoyl-[acp] beta-hydroxyacyl- 1-(3-sn- phosphate urea a (3R)-3- dehydratase [+ 3 isozymes] a (3R)-3- lipid II (meso diphosphatase: KVU_0163 (Acyl-carrier- phosphatidyl) isomerase: pgi urease: FAD dependent FAD dependent β-D-glucopyranose hydroxydecanoyl- UDP-N-acetyl- FabZ: fabZ sulfoquinovosyl an N-terminal L- + 4-nitrophenyl hydroxytetradecanoyl- UDP-N-acetyl- a 3-oxohexanoyl- -sn-glycerol glycogen degradation I a peptidoglycan [DNA] an L-arginyl- O-succinyl-L- menadione NADH H a tripeptide N-ethylglycine SAICAR a holo [BryU acyl- starch D-ribofuranose diaminopimelate containing) short-chain protein) ureA oxidoreductase: oxidoreductase: Arg butanoate 1-phosphate [acp] α-D-glucosamine α diacylglycerol F6P heparin glutamyl-[protein] [tRNA ] homoserine carrier protein] [acp] -D-glucosamine dehydrogenase: dehydratase [acp] 3-phosphate ureB ureC KVU_PA0165 KVU_2024 hydrolase, alpha Kinase, Peptide PA0131 Peptide glycosyltransferase, a maltooligosyl- a (2E)-4-methylpent-2-enoyl-[acp] biosynthesis degradation malonyl CoA- family 51: mrcB GTP ppGpp KVU_2131 FabZ: fabZ short-chain phosphatidylglycerophosphatase: ammonium a glycogen haloacid amylase, pfkB acyl-(Acyl-carrier- acyl-(Acyl-carrier- trehalose UDP-α-D-glucose murein exodeoxyribonuclease NADH Peptidase oxidoreductase, acyl carrier [+ 5 isozymes] enoyl-(Acyl- dehydrogenase: pgpA gly heparin Arginine- O-succinylhomoserine hydrolase: adenylosuccinate dehalogenase- catalytic family protein)--UDP-N- protein)--UDP-N- peptidoglycan a (2E,4S)-4-methylhex- NAD dependent hydrolase: lrgB III: xth dehydrogenase T: pepT FAD-binding protein alpha carrier-protein) enoyl-ACP KVU_2131 an L-1- Heparinase tRNA-protein (Thiol)-lyase KVU_0234 lyase protein: purB like protein subdomain protein: a reduced acetylglucosamine O- acetylglucosamine O- glycosyltransferase: a (3R)-3- 2-enoyl-[acp] epimerase/ β [+ 2 isozymes] (Quinone): protein: KVU_2544 transacylase Guanosine-3',5'- amylase, reductase: fabI-2 reductase: fabI-3 phosphatidyl- -D-fructose 1,6- II/III-like exodeoxyribonuclease transferase: protein: metZ peptidase family protein: protein: treZ rbsK H O c-type acyltransferase: lpxA pbpA hydroxyhexanoyl-[acp] [+ 5 isozymes] dehydratase a malonyl-(MCT): fabD a large- D-ribofuranose 2 acyltransferase: lpxA bis(Diphosphate) 3'- catalytic enoyl-(Acyl- bisphosphate protein: III: xthA1 KVU_0682 KVU_0497 T: pepT KVU_0422 cytochrome a nascent peptidoglycan enoyl-ACP a (3R)-3- sn-glycerol α β branched glucan KVU_1969 an oxidized Guanosine-3',5'- subdomain beta- carrier-protein) enoyl-ACP family an -limit dextrin ditrans,octacis- a peptidoglycan [+ 2 isozymes] -D-glucose [BryU acyl- 5-phosphate UDP-3-O-[(3R)-3- UDP-3-O-[(3R)-3- with (L-alanyl-γ-D-glutamyl- pyrophosphohydrolase: reductase: fabI-3 hydroxyhexanoyl- KVU_1908 ethylamine glyoxylate butanoate 4-nitrophenol AICAR fumarate O c-type reductase: fabI-3 protein: wcaG fructose- 4-deoxy-2-O-sulfo- undecaprenyldiphospho- pentapeptide a 2'- an N-terminal 6-phosphate carrier protein] 2 hydroxydecanoyl]- nucleoside diphosphate KVU_0163 bis(Diphosphate) 3'- protein: treZ hydroxyacyl- reductase: fabI-2 [acp] UDP-α-D- succinate maltose maltose hydroxymyristoyl]-N- meso-2,6-diaminopimeloyl-D- β-L-erythro-hex-4- N-acetyl-(N- [DNA] Arg L-homocysteine a proteinogenic a dipeptide cytochrome N-acetyl-α-D- kinase superfamily pyrophosphohydrolase: (Acyl-carrier- sulfoquinovopyranose bisphosphate glycosyl hydrolase deoxyribonucleoside a tRNA L-arginiyl-L- α enoyl-ACP beta- + maltotriose KVU_1360 maltotriose acetyl- -D-glucosamine alanyl-D-alanine) pentapeptide α,α-trehalose a 5-methylhexanoyl-[acp] aldolase: fbaB enopyranuronosyl- acetylglucosaminyl)muramate 5'-monophosphate glutamyl-[protein] NAD menadiol amino acid glucosamine UDP-3-0-acyl N- protein: ndk KVU_0163 protein) reductase: fabI-3 hydroxyacyl- (Glycogen debranching) maltotetraose maltotetraose phosphatidylglycerol protein: glgX (1,4)-D-N- acetylglucosamine glycosyltransferase, glycosyltransferase, GDP dehydratase 3-oxoacyl-ACP (Acyl-carrier- FabA: fabA biosynthesis II (non-plastidic) sulfoglucosamine deacetylase: lpxC family 51: mrcB family 51: mrcB a (4S)-4-methylhexanoyl-[acp] synthase: fabB protein) an 6-sulfo-α-D- triosephosphate 6-O-sulfate UDP-N-acetyl- Secondary Metabolite Degradation α ω an N-terminal L- 4-nitrophenyl a cis-delta21-39- UDP-3-O-(3- UDP-3-O-(3- [+ 2 isozymes] [+ 2 isozymes] a mature peptidoglycan with beta- [+ 3 isozymes] dehydratase DHAP quinovosyl diacylglycerol isomerase a debranched -limit dextrin maltotetraose α -saturated C55 an L-arginyl- coenzyme A a peptide with a an L-aspartyl- (S)-ureidoglycolate maltose a dipeptide KVU_2491 a dipeptide -D-glucosamine gln + L-cystathionine VibB oxo-40-methyl- a protein hydroxymyristoyl) (L-alanyl-γ-D-glutamyl-meso- hydroxyacyl- 3-oxoacyl-ACP FabA: fabA protein: tpiA dolichol phosphate 2-oxoglutarate NADH H aspartyl-[protein] [tRNA Arg ] leader sequence ITP [tRNA Asn ] palmitate hydroxydecanoyl) glycerol-3- D-glyceraldehyde β C59:1-[acp] ATP-dependent alpha α -α-D-glucosamine a nascent peptidoglycan a nascent peptidoglycan 2,6-diaminopimeloyl-D-alanyl- (Acyl-carrier- synthase: fabB a 6-methyl-3-oxoheptanoyl-[acp] DHAP superpathway of -D- glucose degradation mazG family protein: mazG glutamyl-tRNA cyclopropane- - -D-glucosamine beta- phosphate 3-phosphate D-galacturonate degradation I L-idonate β Lon protease: amylase UDP-3-O-(3- UDP-3-O-(3- with (L-alanyl-γ-D-glutamyl- with D,D cross-links (meso- D-alanine) pentapeptide protein) [+ 3 isozymes] glucuronosides degradation (oxidative) 4-deoxy- -L- alpha-glucoside amidotransferase fatty-acyl- hydroxyacyl- dehydrogenase: glyceraldehyde- degradation Arginine- O-succinylhomoserine acyl carrier signal nucleoside triphosphate hydrolase: ureidoglycolate KVU_PB0073 catalytica dipeptide KVU_1399 a dipeptide hydroxymyristoyl) hydroxymyristoyl) meso-2,6-diaminopimeloyl- diaminopimelate containing) dehydratase short-chain aldehydo-D- erythro-hex-4- ABC transporter glutamate subunit A phospholipid a (6S)-6-methyl-3- (Acyl-carrier- gpsA (Kdo) -lipid A 3-phosphate a β-D-glucuronoside tRNA-protein (Thiol)-lyase protein peptidase pyrophosphohydrolase: KVU_0234 hydrolase: allA region: glucosamine N- D-alanine) tetrapeptide Polyprenyl Biosynthesis dehydrogenase: sn-glycerol 2 D-glucopyranose galacturonate α maltotriose enopyranuronosyl- ATPase synthase (Beta protein: gatA synthase: cfa [+ 2 isozymes] glucosamine N- FabZ: fabZ oxooctanoyl-[acp] protein) Glucuronate L-idonate -D-glucopyranose 1-phosphate transferase: synthase KVU_1153 aglA acyltransferase: KVU_2131 3-phosphate biosynthesis I (E. coli) dehydrogenase: L-sorbosone (1,4)-D-N- AglK: aglK subunit): gltD protein: metZ I: lepB [+ 2 isozymes] a cis-keto-C60- a peptide acyltransferase: dehydratase isomerase alcohol KVU_0682 AcpS: acpS lpxD short-chain [+ 5 isozymes] α-Kdo-(2->4)-α-Kdo- gapB dehydrogenase: alpha amylase sulfoglucosamine IMP an L-asparaginyl- meroacyl-[acp] D-glucopyranose lpxD a mature peptidoglycan Kdo transfer to trans, trans-farnesyl a (2E)-hex-2-enoyl-[acp] FabZ: fabZ glycerol-3- protein: uxaC dehydrogenase Asn UDP-2-N,3-O-bis[(3R)- geranyl dehydrogenase: (2->6)-lipid IV (E. coli) gdhB catalytic region: aglA 6-O-sulfate N-acetyl-α-D-glucosaminyl- [tRNA ] 4-nitrophenol palmitate glyoxylate urea UDP-2-N-[(3R)-3- with D,D cross-links (meso- lipid IV I (E. coli) diphosphate biosynthesis a (3R)-3-hydroxy-6- phosphate lipidA A D-tagaturonate GroES-like UDP an N-terminal 3-hydroxytetradecanoyl]- a nascent peptidoglycan a nascent peptidoglycan with a nascent peptidoglycan a mature peptidoglycan A diphosphate KVU_2131 a (2E)-hex- 13-DPG (C55 ω-saturated pyruvate a holo-[VibB aryl- hydroxydodecanoyl]- enoyl-ACP D-glucopyranuronate protein: idnD phosphoglucomutase- glu + Arg L-homocysteine 3',5'-ADP a leader sequence a peptide α diaminopimelate containing) methylheptanoyl-[acp] acyltransferase biosynthesis membrane-bound maltose NAD a tRNA L-arginiyl-L- -D-glucosamine with L,D cross links (meso- (L-alanyl-γ-D-glutamyl-meso- with (L-alanyl-γ-D-glutamyl- with (L-alanyl-γ-D-glutamyl- CMP-Kdo lipid IV (E. coli) biosynthesis reductase: [+ 5 isozymes] 2-enoyl-[acp] 5-dehydro- 1: pgm dolichyl phosphate) carrier protein] 3-O-[(3R)-3- A IPP PlsY: KVU_0139 lauroyl PQQ-dependent aspartyl-[protein] UDP-2,3- diaminopimelate containing) 2,6-diaminopimelate) tripeptide meso-2,6-diaminopimeloyl- meso-2,6-diaminopimeloyl- fabI-3 beta-hydroxyacyl- phosphoglycerate D-gluconate hydroxydecanoyl]- isopentenyl- IPP a (3R,6S)-3-hydroxy- alcohol acyltransferase acyltransferase: kinase: pgk dehydrogenase, [+ 2 isozymes] amylomaltase: aglA N,6-O-disulfo- α diacylglucosamine glycine) tetrapeptide D-alanine) tetrapeptide (Acyl-carrier-protein) -D-glucosamine 3-deoxy-D-manno- diphosphate geranyl 6-methyloctanoyl-[acp] dehydrogenase family protein: KVU_1800 glucose/quinate/ short-chain D-glucosamine hydrolase protein: a hexanoyl-[acp] dehydratase α-Kdo-(2->4)-α-Kdo-(2-> D-altronate an oxidized (1S,2R)-1- a [protein]-α- a long-linear UDP-2,3- octulosonic-acid delta- diphosphate GroES-like aldehydo-D-glucuronate shikimate family dehydrogenase: N 5 -methyltetrahydromethanopterin an oxidized c- (S)-lactate a 2'-deoxyribonucleoside 2-oxoglutarate O-phospho- methylglyoxal an L-glutamyl- KVU_1101 beta-hydroxyacyl- FabA: fabA KVU_0109 6)-(lauroyl)-lipid IV (E. coli) 3-phospho-D-glycerate D-glucopyranose [DNA] D-ala ser C-(indol-3- cys repressor LexA α-D-glucan pro diacylglucosamine a mature peptidoglycan a mature peptidoglycan with synthase: ispA protein: mecR A idnO factor 420 type cytochrome 5'-triphosphate L-homoserine L-glutamate [tRNA Gln ] GTP transferase: isomerase, geranyl 3-oxoacyl- (Acyl-carrier- a 1-acyl-sn protein: gcd yl)glycerol glyoxalase/bleomycin Chemotaxis protein alpha hydrolase protein: with L,D cross-links (meso- (L-alanyl-γ-D-glutamyl-meso- a mature peptidoglycan KVU_2299 type 1: beta-hydroxyacyl- [+ 2 isozymes] -glycerol 3- phosphoglycerate phosphoglycerate Glucuronate D-glucono- aspartyl/ SOS response lipid X diphosphate ACP protein) D-gluconate 3-phosphate resistance protein/ methyltransferase, diguanylate amylase, Proline KVU_1101 diaminopimelate containing) 2,6-diaminopimelate) tripeptide with (L-alanyl-γ-D-glutamyl- KVU_0071 (Acyl-carrier-protein) phosphate mutase, 2,3- mutase, 2,3- isomerase 1,5-lactone N-sulfo-D- coenzyme F420-dependent glutamyl-tRNA transcriptional synthase: fabB dehydratase 2-dehydro- glucokinase: glk DNA polymerase dioxygenase CheR-like protein: cyclase (GGDEF) catalytic racemase A: lipid-A- meso-2,6-diaminopimeloyl- α-Kdo-(2->6)- DMAPP dehydratase a hexanoyl-[acp] acyltransferase α-D-Kdo-(2->4)-α-D- bisphosphoglycerate- bisphosphoglycerate- protein: uxaC SMP-30/ thermoresistant glucosamine N5,N10-methylene L-lactate class IV O-succinylhomoserine amidotransferase: repressor, lipid X (P. putida) FabA: fabA 3-deoxy-D- III subunit delta': tryptophan protein: KVU_0465 KVU_PB0071 domain-containing subdomain KVU_PB0058 disaccharide glycine) tetrapeptide lipid IV (E. coli) [+ 3 isozymes] FabZ: fabZ family protein: Kdo-(2->6)-lipid A (E. coli) independent: gpmI independent: gpmI Gluconolaconase/ gluconokinase- tetrahydromethanopterin dehydrogenase aminotransferase: (Thiol)-lyase pepN gatB lexA: lexA A D-fructuronate gluconate KVU_2483 synthase: [+ 2 isozymes] cleaved protein: treZ synthase: lpxB geranyl beta-hydroxyacyl- 3-oxoacyl- KVU_0144 like protein: gntK reductase: KVU_1411 (cytochrome): lctB KVU_2546 protein: metZ [+ 4 isozymes] a [protein]-L- [+ 3 isozymes] protein: KVU_1009 a linear malto- D-proline lipid-A- a 3-oxooctanoyl-[acp] LRE-like protein 2-keto-3- trpB trpA repressor LexA lipid A disaccharide diphosphate (Acyl-carrier- a (2E)-6-methylhept-2-enoyl-[acp] ACP 2-phospho-D-glycerate mannitol [+ 15 isozymes] (R)-lactate glutamate-O 5 an L-glutaminyl- [+ 2 isozymes] oligosaccharide disaccharide acyltransferase: region family deoxygluconate gluconate Gln protein) synthase: [tRNA ] c-di-GMP synthase: lpxB (E. coli) α-Kdo-(2->4)-α-Kdo- synthase: ispA short-chain KVU_0791 dehydrogenase protein: KVU_0536 kinase: kdgK kinase 2; D-glucopyranose 6-phosphate D-glucosamine D-glyceraldehyde -methyl-ester dehydratase enoyl-(Acyl- fabB 5,10-methylene- a reduced a reduced c- pyruvate pyruvate lipid A tetraacyldisaccharide (2->6)-lipid IV (E. coli) geranyl dehydrogenase: a 1,2-diacyl- enolase: eno domain- [+ 2 isozymes] gluconate D-glt 3-phosphate trp L-cystathionine A FabZ: fabZ carrier-protein) enoyl-ACP tetrahydromethanopterin factor 420 type cytochrome [DNA] 4'-kinase: lpxK diphosphate [+ 3 isozymes] sn-glycerol containing KDGP disaccharide KVU_2131 reductase: fabI-2 reductase: fabI-3 transport, D-sorbitol (P. putida) a (2E,6S)-6-methyloct- a 3-oxooctanoyl- 3-phosphate protein: uxuB D-gluconate GNT I degradation I lipid IV (E. coli) polyprenyl [+ 5 isozymes] enoyl-ACP phosphatidate phosphoenolpyruvate 2-dehydro-3- A 2-enoyl-[acp] [acp] system: tetraacyldisaccharide synthetase a (3R)-3- reductase: fabI-3 cytidylyltransferase: D-mannonate Dehydrogenase deoxyphosphogluconate a peptidoglycan an [amino group carrier idnK D-sorbitol methylmalonate semialdehyde glycyl-glycine glutathione a 2'-deoxyribonucleoside sulfite GSSH a uridylylated γ an N-carbamoyl hydantoin L(or D)-O- an unfolded 4'-kinase: lpxK superfamily enoyl-(Acyl- short-chain pyruvate cytochrome c aldolase/4-hydroxy-2- [DNA] dimer (generic) 3'-AMP protein]-C-terminal- - a protein Carbohydrate Biosynthesis hydroxyoctanoyl-[acp] cdsA Mannonate sorbitol 5'-triphosphate PII protein D-amino acid phosphoserine protein lipid IV protein: ispA carrier-protein) enoyl-ACP dehydrogenase: kinase: pykA subunit: gadh2 oxoglutarate aldolase D-gluconate (L-glutamyl)-L-glutamate Hydantoinase A a 6-methylheptanoyl-[acp] a CDP- dehydratase dehydrogenase: 2',3'-cyclic-nucleotide nitrilase/cyanide phosphoserine ATP-dependent (P. putida) (2E,6E)-farnesyl beta- reductase: fabI-2 reductase: fabI-3 KVU_2131 2-keto-D- subfamily protein: eda 6-phosphate acetylglutamate beta subunit- Chaperonin diacylglycerol pyruvate 1: uxuA sldC methylmalonate- gamma- 3-mercaptopyruvate lytic 2'-phosphodiesterase: hydratase and phosphatase Clp protease gluconeogenesis I diphosphate hydroxyacyl- enoyl-ACP [+ 5 isozymes] gluconate DNA polymerase UTP-GlnB kinase: argB like protein: HslO: hslO O-antigen building blocks biosynthesis (E. coli) CMP-3-deoxy-D-manno- GDP-mannose biosynthesis GDP-L-fucose 3-oxoacyl-ACP CDP-diacylglycerol-- sorbitol semialdehyde glutamyltransferase sulfurtransferase: transglycosylase: cpdB apolipoprotein N- SerB: serB proteolytic (Acyl-carrier- reductase: fabI-3 a (3R)-3- 2-dehydro-3- pyruvate III subunit delta': uridylyltransferase, KVU_PB0168 octulosonate biosynthesis biosynthesis I (from synthase: fabB glycerol-3-phosphate 3- dehydrogenase: Degradation/Utilization/Assimilation - Other dehydrogenase 1: ggt KVU_1838 KVU_0594 an [amino group carrier acyltransferase: subunit: clpP UDP-α-D- α D-glucopyranose protein) hydroxyoctanoyl- deoxy-D-gluconate KVU_2483 GlnD: glnD [+ 3 isozymes] (S)-malate -D- D-glucopyranose D-ribulose GDP-D-mannose) [+ 3 isozymes] phosphatidyltransferase: sldC (Acylating) protein: iolA [+ 4 isozymes] [+ 2 isozymes] [+ 6 isozymes] adenosine protein]-C-terminal- KVU_0825 serine a peptide a protein dehydratase [acp] 2-keto-3- [+ 15 isozymes] γ galactose glucopyranose 6-phosphate 6-phosphate a (6S)-6-methyloctanoyl-[acp] 2-dehydro- keto-D-fructose -(5-phospho-L- a D-amino acid N-carbamoylglycine UDP- glucose-6- 5-phosphate glucose-6- GDP-α-D-mannose FabA: fabA an 8-methyl-3-oxononanoyl-[acp] beta- pgsA deoxygluconate nylon-6 oligomer degradation 1-phosphate sugar 1-(3-sn- 6-phospho- acrylonitrile GlcNAc-1,6- UMP glutamyl)-L-glutamate Malate/L-lactate galactopyranose mannose-1- phosphate phosphate NAD(P)-binding 3-oxoacyl-ACP hydroxyacyl- kinase: kdgK γ-L-glutamyl- a lipid II isomerase: beta- D-gluconate degradation I hydrogencarbonate NADH propanoyl-CoA H + a PII protein dehydrogenase mutase: glf phosphate isomerase: isomerase: pgi GDP-D-mannose short-chain (Acyl-carrier- phosphatidyl) 6-aminohexanoate L-cysteinylglycine [DNA] glutathione thiosulfate anhydro-MurNAc- aldehydo-D-kdsD hydroxyacyl- synthase: fabB nylon-6 polymer glycylglycine family protein: UDP-Galf guanyltransferase pgi F6P dehydratase: gmd dehydrogenase: protein) -sn-glycerol KDGP cyclic dimer pentapeptide arabinose 5- GDP-4-dehydro- (Acyl-carrier- [+ 3 isozymes] 3-phosphate acrylonitrile KVU_PB0044 α beta: rfbA F6P KVU_2131 dehydratase β-D-fructofuranose dTDP- -D-glucose phosphate mannose-6- α-D-rhamnose protein) an (8S)-8-methyl-3- FabA: fabA phosphatidylglycerophosphatase: D-gluconate a mitochondrial preprotein an N-terminal- 1-arachidinoyl- 1-oleoyl-sn malate phosphate Fucose dehydratase oxodecanoyl-[acp] [+ 5 isozymes] carbohydrate a 1-acyl-2-lyso- S-(2-hydroxyacyl) dTDP- glucosamine- pgpA 2-dehydro-3- 6-phosphate a reduced ferredoxin isovalerate including a mitochondrial L-methionyl-L- 3'-GMP 4-nitrobenzaldehyde sn-glycerol -glycerol 3- DHAP dehydrogenase isomerase synthetase Fcl: fcl FabZ: fabZ a (3R)-3-hydroxy-8- beta- kinase, 6-aminohexanoate a nylon-6 2-oxoglutarate gln H + phosphatidylethanolamine glutathione a protein glu glucose 4,6- -fructose-6- short-chain an L-1- deoxyphosphogluconate acrylamide [iron-sulfur] cluster targeting sequence cysteinyl-[protein] aryl-alcohol 3-phosphate phosphate glycerol-3- (NAD): mdh protein: methylnonanoyl-[acp] hydroxyacyl- PfkB: cscK linear dimer linear oligomer 2',3'-cyclic-nucleotide acyltransferase: acyltransferase: peptidase, T1A dehydratase: phosphate D-arabinofuranose GDP-4-dehydro-6- dehydrogenase: phosphatidyl- aldolase/4-hydroxy-2- dehydrogenase- phosphate glutamate KVU_2173 β a (2E)-oct-2-enoyl-[acp] (Acyl-carrier- synthetase/ KVU_0791 (Proteasome) rfbB aminotransferase, 5-phosphate deoxy- -L-galactose KVU_2131 sn-glycerol oxoglutarate aldolase 6-caprolactam Lysophospholipase acetate-CoA ligase, hydroxyacylglutathione 2'-phosphodiesterase: KVU_0791 racemase: beta-hydroxyacyl- protein) F6P beta- beta- amidase YgiC: peptidase, M16 methionine like protein dehydrogenase: family protein: oxaloacetate dTDP-4-dehydro- isomerizing: mannose-6- Fucose subfamily protein: eda glutamate synthase L1 and related AMP-dependent: hydrolase: KVU_2008 cpdB acyltransferase acyltransferase KVU_1664 pyruvate 2-dehydro-3- enoyl-ACP [+ 5 isozymes] (Acyl-carrier-protein) dehydratase lactamase: lactamase: KVU_1994 family protein: aminopeptidase, oxidoreductase: gpsA KVU_1190 6-deoxy-α-D- KVU_0416 phosphate synthetase Fcl: fcl (Ferredoxin): gltB esterase-like KVU_1477 hydroxyacylglutathione family protein: family protein: sn-glycerol deoxyphosphooctonate reductase: a (3R,8S)-3-hydroxy- dehydratase FabZ: fabZ KVU_2031 KVU_2031 KVU_0314 type I: map2 KVU_PA0059 D-glt glucopyranose isomerase-like D-glyceraldehyde [+ 2 isozymes] protein: KVU_0528 hydrolase: gloB guanosine 4-nitrobenzyl a 1-arachidonoyl-KVU_0144 KVU_0144 3-phosphate a peptide phosphoenolpyruvate glucosamine- aldolase: KVU_0399 β fabI-3 FabA: fabA pyruvate bisoleoyl protein: pmi GDP- -L-fucose 8-methyldecanoyl-[acp] a (2E)-oct- 3-phosphate alcohol 2-acyl-sn-glycerol carboxykinase: pckA DTDP-4- -fructose-6- 3-deoxy-8- beta-hydroxyacyl- stearate acrylate phosphatidate D-mannopyranose 2-enoyl-[acp] an oxidized ferredoxin isovaleryl-CoA diphosphate an N-terminal L- 3-phosphate dehydrorhamnose phosphate phosphooctulonate an octanoyl-[acp] beta-hydroxyacyl- (Acyl-carrier-protein) biosynthesis III (fungi) 6-aminohexanoate glu sn-glycero-3- AMP a 2-hydroxy an MPP-processed 6-phosphate [iron-sulfur] cluster a carboxylate glutathione a peptide met cysteinyl-[protein] 3,5-epimerase, aminotransferase, synthase (Acyl-carrier- dehydratase alcohol phosphoethanolamine carboxylate mitochondrial protein phosphoenolpyruvate 3-oxoacyl- a palmitoyl-[acp domain putative: galE1 isomerizing: glmS protein: kdsA phosphoglucomutase/ protein) FabZ: fabZ dehydrogenase phosphomannomutase ACP dehydratase within a fatty acid synthase] dTDP-4- D-glucosamine α GroES-like Long-chain-fatty- enolase: eno UDP- -D-glucose synthase: fabB FabA: fabA UDP-N-acetyl-α-D- 4-methyl-3- a D-5- dehydrorhamnose 6-phosphate KDO-8P alpha/beta/alpha a (2E)-8-methylnon-2-enoyl-[acp] protein: mecR acid--CoA ligase: Nucleoside and Nucleotide Degradation C1 Compound Utilization di-trans,octa-cis- 1-(oleoyl)-sn-glycero-3- a single- a ribonucleoside biosynthesis [+ 3 isozymes] 6-oxohexanoate muramoyl-L-alanyl-γ-D- pyruvate ser glyoxylate a [protein] Ser/Thr 4-hydroxybenzoate (+)-trans-carveol D-arginine oxoadipate- a DNA segment monosubstituted 3,5-epimerase phosphoglucomutase/ domain I: noeK beta-hydroxyacyl- [+ 2 isozymes] a 3-oxooctadecanoyl-KVU_1613 and Assimilation undecaprenyl phosphate phosphoethanolamine stranded RNA diphosphate α D-glucopyranose glutamyl-L-lysyl-D-alanine Hpr serine kinase/ p-hydroxybenzoate carveol ribonucleoside- enol-lactone recombinase hydantoin 2-phospho-D-glycerate related protein: rfbC phosphomannomutase -D-mannose (Acyl-carrier- enoyl-(Acyl- [acp domain within purine nucleotides degradation II (aerobic) D-amino acid putative hydantoin 6-phosphate a 3-oxodecanoyl-[acp] enoyl-ACP superpathway of purine deoxyribonucleosides degradation formaldehyde oxidation phosphatase hydroxylase dehydrogenase diphosphate A: recA dTDP-4-dehydro- family protein 1-phosphate phosphoglucomutase- protein) carrier-protein) an octanoyl-[acp] a fatty acid synthase] pyruvate dehydrogenase Lysophospholipase polyribonucleotide dehydrogenase hydrolase or racemase: phosphoglycerate reductase: fabI-3 Long-chain-fatty- VII (THF pathway) glycosyl domain-containing transcriptional ((+)-trans-carveol reductase class recombinase β-L-rhamnose MrsA: KVU_0507 mannose-1-phosphate 1: pgm dehydratase reductase: fabI-2 complex, E2 component, L1 and related nucleotidyltransferase class V small subunit: acyltransferase: hyuE mutase, 2,3- α-Kdo short-chain acid--CoA ligase: transferase, protein: hprK activator: dehydrogenase) Ib glutaredoxin: B: KVU_2262 dTDP-4- α-D-glucosamine guanylyltransferase: [+ 2 isozymes] FabZ: fabZ enoyl-ACP adipate dihydrolipoamide esterase-like protein: pnp aminotransferase: KVU_PB0059 pcaD a DNA segment an L-5- bisphosphoglycerate- α-D-glucopyranose dehydrogenase: KVU_1613 AMP IMP formaldehyde family 4: mraY KVU_PB0199 : KVU_2035 nrdH nrdE nrdF 4-methyl-3- dehydrorhamnose 1-phosphate 3-deoxy-D-manno- xanB reductase: fabI-3 2'-deoxyguanosine acetyltransferase: pdhB protein: KVU_0528 KVU_1756 Signal transduction a 2'- [+ 3 isozymes] in reverse monosubstituted independent: gpmI 1-phosphate KVU_2131 a (2E,8S)-8-methyldec- a (3R)-3- oxoadipate reductase: octulosonate 2'-deoxyadenosine histidine kinase: protocatechuate (+)-carvone deoxyribonucleoside 5-guanidino-2- orientation hydantoin nucleotidyl GDP-α-D-mannose [+ 5 isozymes] 2-enoyl-[acp] an 8-methylnonanoyl- hydroxyoctadecanoyl- 5'-nucleotidase IMP a single- KVU_2403 cytidylyltransferase: nucleotidyl undecaprenyl-diphospho-N UMP a nucleoside KVU_PA0149 5'-diphosphate oxopentanoate 3-phospho-D-glycerate transferase [acyl-carrier protein] (5Z)-dodecenoate [acp domain within surE: surE dehydrogenase/ a 5,10- γ sn-glycero-3- stranded RNA hydroxypyruvate a [protein] (L-serine/L- dTDP-β-L- kdsB transferase a (3R)-3- enoyl-(Acyl- -acetylmuramoyl-L-alanyl- - acetyl-CoA CO NADH oleate diphosphate gly family a fatty acid synthase] GMP reductase, inosine methylenetetrahydrofolate 2 superfamily hydroxydecanoyl-[acp] carrier-protein) enoyl-ACP 3-oxoacyl-ACP biosynthesis I Ser/Thr protein D-glutamyl-L-lysyl- D-alanine phosphoethanolamine threonine) phosphate phosphoglycerate rhamnose protein: glmU Long-chain-fatty- transglutaminase- adenosine guanosine and CMP-Kdo protein: gtaB reductase: fabI-2 reductase: fabI-3 synthase: fabB a (3R)-3- phosphatase/ methylenetetrahydrofolate kinase: pgk N-acetyl-α-D- beta- acid--CoA ligase: like protein: deaminase: xanthosine enoyl-ACP [+ 3 isozymes] hydroxydecanoyl- nucleotidase: dehydrogenase: KVU_1690 α hydroxyacyl- 38- glucosamine UDP- -D-glucose KVU_1613 KVU_0087 add phosphorylase UDP-N-acetyl- (2E,6E)-farnesyl a non-methylated a uridine an aromatic a [protein]- 13-DPG (Acyl-carrier- reductase: fabI-3 [acp] beta- a (2E)-octadec-2-enoyl- KVU_1714 a 5,10- α isobutanoate sulfite carbamoyl canavaninosuccinate a O- squalene 1-phosphate a 1o-methyl-3-oxoundecanoyl-[acp] inosine-5'- inosine family Ins(3)P -D-glucosamine diphosphate protoheme L-ornithine ribosomal 40 in tRNA primary alcohol ethylphosphate L-histidine glycogen biosynthesis I (from ADP-D-Glucose) protein) hydroxyacyl- [acp domain within GMP methenyltetrahydrofolate phosphate sialoglycoprotein Sensor phytoene/ nucleotidyl an (8S)-8-methyldecanoyl- monophosphate guanosine and protein: deoD protein L11ribosomal ribosomal aryl-alcohol alkaline glyceraldehyde- dehydratase (Acyl-carrier- a fatty acid synthase] adenosine O-sialoglycoprotein protein: squalene transferase [acyl-carrier protein] short-chain dehydrogenase: xanthosine 2'-deoxyinosine methenyltetrahydrofolate protein L11 large subunit dehydrogenase- phosphatase: 3-phosphate D-glucopyranose 6-phosphate FabA: fabA protein) Long-chain-fatty- 5'-nucleotidase D-inositol-3-phosphate Sulfite reductase argininosuccinate endopeptidase: KVU_PB0051 synthetase: family dehydrogenase: guaB phosphorylase cyclohydrolase: KVU_1690 acetate-CoA ligase, AMP- protoheme IX Ornithine methyltransferase: pseudouridine like protein KVU_2387 triosephosphate dehydrogenase: 3-oxoacyl-ACP dehydratase acid--CoA ligase: surE: surE glycosyltransferase: dependent: KVU_1477 [NADPH] farnesyltransferase: lyase: KVU_0151 KVU_2182 synthase A: rluA oxidoreductase: [+ 8 isozymes] KVU_0582 protein: glmU beta- KVU_2131 adenosine family an N 10 - carbamoyltransferase prmA [+ 2 isozymes] a [protein]- isomerase gapB phosphoglucomutase- synthase: fabB FabA: fabA KVU_1613 Ser/Thr protein inosine murG flavoprotein alpha- Argininosuccinate a methylated presqualene UDP-N-acetyl- hydroxyacyl- [+ 5 isozymes] deaminase: add protein: deoD pseudouridine formyltetrahydrofolate cox10 protein: argF a peptide [+ 4 isozymes] KVU_PA0059 N-phospho- protein: tpiA 1: pgm [+ 3 isozymes] phosphatase/ XMP guanosine and component: cysJ lyase 2: asaL ribosomal a pseudouridine 38- an aromatic ethanol diphosphate D-glyceraldehyde α-D-glucosamine (Acyl-carrier- beta- a stearoyl-[acp domain degradation L-histidine DHAP 3-phosphate [+ 2 isozymes] a (10S)-10-methyl-3- a (3R)-3-hydroxy-10- hydroxyacyl- within a fatty acid synthase] nucleotidase: xanthosine Formyl protein L11 40 in tRNA aldehyde protein) 5'-nucleotidase phosphorylase transferase, N- 1-O-(2-acetamido-2-deoxy- UDP isobutanoyl-CoA diphosphate α-D-glucopyranose oxododecanoyl-[acp] methylundecanoyl-[acp] (Acyl-carrier- inosine KVU_1714 pseudouridine α AMP ferroheme o dehydratase -D-glucopyranosyl)-1D- + 1-phosphate Long-chain-fatty- surE: surE family terminal: purU hydrogen sulfide NADP H O L-citrulline L-canavanine fumarate FabZ: fabZ short-chain beta-hydroxyacyl- protein) acid--CoA ligase: myo-inositol 3-phosphate 2 glucose-1-phosphate dehydratase inosine guanosine Ser/Thr protein protein: deoD fructose- dehydrogenase: (Acyl-carrier-protein) KVU_1613 α formate adenylyltransferase FabZ: fabZ guanosine and phosphatase/ 2-deoxy- -D- pseudouridine bisphosphate a (2E)-dec-2-enoyl-[acp] KVU_2131 dehydratase a (2E)-dec- ribose 1-phosphate xanthosine nucleotidase: 5'-phosphate 10 peptidoglycan 967 37 527 1: glgC [+ 5 isozymes] FabA: fabA stearoyl-CoA inosine an L-methionyl- an N - O-succinyl-L- a ribonucleoside a cytosine a guanine a guanine (S)-2- (2E,6E)-farnesyl aldolase: fbaB 2-enoyl-[acp] phosphorylase KVU_1714 methanethiol a protein with glutathione a single DAP-DAP an aldehyde DNA with lesion gly enoyl-ACP guanosine and phosphopentomutase Met formyltetrahydrofolate triphosphate in 16S rRNA in tRNA in 16S rRNA hydroxyglutarate diphosphate a (1->4)-α-D-glucan ADP-α-D-glucose a (3R,10S)-3-hydroxy-10- beta-hydroxyacyl- family ribosomal [initiator tRNA ] homoserine a disulfide bond stranded DNA crosslink rRNA small subunit excinuclease reductase: beta- putative xanthosine protein: deoB tRNA (guanine-N(1)- ribosomal RNA NAD-binding D- membrane- oxidoreductase, phytoene/ methyldodecanoyl-[acp] (Acyl-carrier-protein) protein: deoD xanthosine large subunit Aldehyde Degradation methyltransferase ABC, B ADP-glucose:starch fabI-3 hydroxyacyl- esterase/lipase/ phosphorylase 2-deoxy-D-ribose )-methyltransferase: small subunit isomer specific bound aldehyde FAD-binding squalene β-D-fructose 1,6- dehydratase pseudouridine O-succinylhomoserine DNA primase B: KVU_0793 subunit: uvrB glucosyltransferase, beta-hydroxyacyl- (Acyl-carrier- thioesterase;acyl- family 5-phosphate peptidoglycan trmD methyltransferase 2-hydroxyacid dehydrogenase, protein: synthetase: FabZ: fabZ synthase D: rluD methionyl-tRNA 1 bisphosphate a decanoyl-[acp] protein) coa thioester hypoxanthine protein: deoD methylglyoxal degradation I (Thiol)-lyase glutaredoxin: (bacterial type) an N - 7 G: gidB dehydrogenase: large subunit: [+ 2 isozymes] gt5A: glgA (Acyl-carrier- formyltransferase: fmt amidase ribosomal RNA an N - KVU_2544 KVU_0582 tRNA protein: metZ grxC : KVU_PA0036 methylguanine 37 serA KVU_2415 DNA without Fructose-1,6- protein) dehydratase hydrolase protein: inosine deoxyribose- MepA: mepA small subunit methylguanine 527 squalene a (1->4)-α-D-glucan a (2E)-10-methylundec-2-enoyl-[acp] pseudouridine lesion glyoxylate bisphosphatase, 3-oxoacyl- dehydratase FabA: fabA KVU_PA0186 guanine guanosine and phosphate methylglyoxal methyltransferase in tRNA in 16S rRNA 2-oxoglutarate a carboxylate synthase B: truB class II: glpX 1,4-alpha-glucan ACP FabA: fabA enoyl-(Acyl- a (3Z)-dec- putative Xanthine xanthosine aldolase: purine ribonucleosides degradation Lactoylglutathione an N-formyl- succinate a protein with ssDNA/pppN(pN) peptidoglycan peptidoglycan B: KVU_1909 a tetrahydrofolate met GSSG a 5-methylcytosine 967 branching synthase: fabB carrier-protein) enoyl-ACP 3-enoyl-[acp] esterase/lipase/ dehydrogenase phosphorylase deoC uracil lyase: gloA L-methionyl- reduced L- hybrid tetrapeptide, tripeptide, F6P beta-hydroxyacyl- met n -1 in 16S rRNA enzyme (Alpha [+ 3 isozymes] reductase: fabI-3 thioesterase: accessory Chlorohydrolase family [initiator tRNA ] cysteine residues glycan chain 2 glycan chain 1 (Acyl-carrier- reductase: fabI-2 3-oxoacyl- Lactoylglutathione glucose-6- amylase KVU_PB0175 factor: xdhC family protein: guaD protein: deoD D-glyceraldehyde adenosine lyase: lguL a 3-oxododecanoyl-[acp] protein) enoyl-ACP ACP acetaldehyde (R)-S- phosphate protein): glgB 3-phosphate dehydratase reductase: fabI-3 synthase: stearate lactoylglutathione RNase E mRNA a DNA containing a 1-acyl-sn-glycero- β-D-fructofuranose a 23S rRNA (R)-2- L-gulono- a [protein]- isomerase: pgi adenosine dethiobiotin a sulfurated hydrogen selenide a myo-inositol L-idonate GGPP a glycogen short-chain FabZ: fabZ fabH xanthine hydroxyacylglutathione SAM O-acetyl-L-serine processing an apurinic/ 3-phosphocholine 1-phosphate uridine 1911/1915/1917 hydroxyglutarate 1,4-lactone L-tyrosine D-glucopyranose deaminase: [sulfur carrier] monophosphate alcohol dehydrogenase: an 10-methylundecanoyl-[acp] [+ 3 isozymes] hydrolase: gloB substrate apyrimidinic site ribosomal myo-inositol-1(or 4) NAD-binding D- gluconolactonase phosphateprotein phytoene/ 6-phosphate a (2E,10S)-10- Xanthine add dehydrogenase KVU_2131 a (5Z)-3- large subunit -monophosphatase isomer specific protein (Calcium- tyrosine/serine squalene methyldodec-2-enoyl-[acp] dehydrogenase hydroxyacylglutathione Biotin cysteine Lysophospholipase fructose- GroES-like [+ 5 isozymes] 3-oxoacyl-ACP oxododec- acetyl-CoA pseudouridine protein: suhB 2-hydroxyacid binding regucalcin- phosphatase: synthetase: accessory xanthosine adenosine inosine guanosine hydrolase: KVU_2008 synthase: synthase A: ribonuclease endonuclease L1 and related bisphosphate protein: idnD enoyl-(Acyl- synthase: fabB 5-enoyl-[acp] synthase D: rluD [+ 2 isozymes] dehydrogenase: like protein) KVU_1759 KVU_0582 a (3R)-3- carrier-protein) enoyl-ACP [+ 3 isozymes] short-chain factor: xdhC KVU_0534 KVU_1110 E: rne III: nth esterase-like aldolase: fbaB a pseudouridine 1911/ serA : KVU_1416 5-dehydro- a [protein]- (R)-lactate myo-inositol 15-cis-phytoene hydroxydodecanoyl-[acp] reductase: fabI-2 reductase: fabI-3 dehydrogenase: protein: KVU_0528 1915/1917 in 23S rRNA D-gluconate L-tyrosine urate 2-oxoglutarate L-gulonate a 12-methyl-3-oxotridecanoyl-[acp] KVU_PA0057 inosine inosine inosine inosine beta- enoyl-ACP biotin 5'-deoxyadenosine an unsulfurated acetate RNase E a 3'-terminal a 5'-phospho- DHAP D-glyceraldehyde hydroxyacyl- reductase: fabI-3 [+ 5 isozymes] guanosine and guanosine and guanosine and guanosine and met L-selenocysteine an mRNA fragment processing sn-glycero-3- short-chain UTP and CTP dephosphorylation I [sulfur carrier] unsaturated sugar [DNA] a carboxylate (Acyl-carrier- a (3R,5Z)-3- xanthosine xanthosine xanthosine xanthosine product mRNA phosphocholine a (10S)-10- dehydrogenase: protein) hydroxydodec- phosphorylase phosphorylase phosphorylase phosphorylase pyruvate methyldodecanoyl-[acp] KVU_2131 5-enoyl-[acp] UTP family family family family dehydratase α [+ 5 isozymes] thymine degradation UDP-N-acetyl- -D-muramoyl- peptidoglycan D- 955/2504/ (S)-1-pyrroline- 3-oxoacyl-ACP beta- protein: deoD protein: deoD protein: deoD protein: deoD di-trans,octa-cis- + uridine FabA: fabA CTP Ham1-like L-alanyl-γ-D-glutamyl-L- hydroxypyruvate gly GSSG a xanthine NADPH NAD ampicillin glyoxal L-idonate D-ala a dipeptide synthase: fabB hydroxyacyl- undecaprenyl phosphate alanyl-DAP crosslink 2580 in 23S rRNA 5-carboxylate asp beta- a (3R)-3-hydroxy-12- synthase: pyrG protein: lysyl-D-alanyl-D-alanine dehydrogenase Beta-lactamase ribosomal aryl-alcohol alcohol (Acyl-carrier- thymine α-D-ribose- proline aspartate oxidoreductase, dipeptidase hydroxyacyl- [+ 3 isozymes] methyltridecanoyl-[acp] KVU_2242 domain large subunit dehydrogenase- dehydrogenase protein) 1-phosphate NAD(P)+ peptidoglycan dehydrogenase aminotransferase FAD-binding AC: (Acyl-carrier- a (12S)-12-methyl-3- beta-hydroxyacyl- CTP class V Thiol-disulfide protein: gumP pseudouridine like protein GroES-like dehydratase 5'-deoxyadenosine degradation I glycosyl transferase, transhydrogenase: amidase family protein: putA protein: KVU_0981 protein: KVU_0070 protein) oxotetradecanoyl-[acp] (Acyl-carrier-protein) 5,6-dihydrothymine UDP phosphopentomutase family 4: mraY aminotransferase: oxidoreductase [+ 6 isozymes] synthase D: rluD oxidoreductase: protein: idnD FabZ: fabZ Ham1-like pntB pntA MepA: mepA (4S)-2-[(S)-[(2R)-2-amino-2- 955/ [+ 4 isozymes] KVU_2544 a proteinogenic dehydratase short-chain dehydratase protein: deoB KVU_1756 D: KVU_2291 a pseudouridine glu KVU_PA0059 5-dehydro- beta- Hydantoinase protein: 5'-deoxyadenosine phenylacetamido](carboxylato) 2504/2580 in 23S rRNA oxaloacetate D-gluconate pyruvate amino acid FabZ: fabZ dehydrogenase: FabA: fabA beta subunit- KVU_2242 D-ribose 5- glycolaldehyde hydroxyacyl- undecaprenyl-diphospho-N- peptidoglycan peptidoglycan methyl]-5,5-dimethyl-1,3- KVU_2131 beta-hydroxyacyl- like protein: 5'-methylthioadenosine phosphate UMP + a (2E)-dodec- (Acyl-carrier- CDP UMP acetylmuramoyl-L-alanyl-γ-D- glyoxylate ser glutathione a xanthine oxidase NADH NADP tetrapeptide, tetrapeptide, thiazolidine-4-carboxylate 2-enoyl-[acp] [+ 5 isozymes] (Acyl-carrier-protein) KVU_PB0168 phosphorylase (MtnP- pyrimidine deoxyribonucleotides glycan chain 1 glycan chain 2 protein) 5'-nucleotidase glutamyl-L-lysyl- D-alanyl-D-alanine enoyl-ACP a (3R,12S)-3-hydroxy-12- dehydratase dehydratase [+ 3 isozymes] like protein): KVU_0318 dephosphorylation FabZ: fabZ surE: surE reductase: methyltetradecanoyl-[acp] FabA: fabA 3-(carbamoylamino)- 5-deoxy-α-ribose mazG family protein: mazG Ser/Thr protein an [HPr]- phosphoenol all-trans- a [protein]- a guanine 46 a [phospholipid]- fabI-3 2-methylpropanoate CMP 1-phosphate nucleoside triphosphate D-cellobiose a [protein]-L-lysine roseoflavin [DNA] a phosphate a nucleoside beta-hydroxyacyl- a (2E)-12-methyltridec-2-enoyl-[acp] a (2E,5Z)-dodeca- phosphatase/ L-histidine pyruvate asp CAIR 4-hydroxybenzoate nonaprenyl L-glutamine dGTP in tRNA a protein oleate N-carbamoyl- 5'-nucleotidase pyrophosphohydrolase: monoester triphosphate (Acyl-carrier- 3,5-dienoyl-[acp] nucleotidase: adenosine diphosphate FMN methyltransferase DNA polymerase metalloprotease cyclopropane- alkaline a dodecanoyl-[acp] beta-alanine surE: surE KVU_1153 mazG family protein: mazG Ham1-like protein) enoyl-(Acyl- enoyl-ACP KVU_1714 nucleotides dCTP dCMP adenylyltransferase / superfamily III subunit chi: transmembrane fatty-acyl- phosphatase: enoyl-ACP amidohydrolase phosphoenolpyruvate- Glycosyltransferase nucleoside triphosphate protein: dehydratase carrier-protein) reductase: Ser/Thr protein degradation III phosphoribosylaminoimidazole- 4-hydroxybenzoate transglutaminase riboflavin kinase: ribF protein: trmB KVU_1144 protein: KVU_1025 phospholipid dedA2 reductase: fabI-3 protein: amaB uridine 5-deoxy-D-ribulose protein 36: KVU_PA0080 pyrophosphohydrolase: 7 KVU_2242 3-oxoacyl- FabA: fabA reductase: fabI-2 fabI-3 phosphatase/ succinocarboxamide synthetase polyprenyltransferase: protein: KVU_1191 roseoflavin an N - [+ 10 isozymes] [+ 2 isozymes] synthase: cfa [+ 2 isozymes] mazG family protein: mazG phosphotransferase: ptsP 46 a nucleoside enoyl-ACP nucleotidase: 1-phosphate (SAICAR synthetase): purC ubiA KVU_1153 methylguanine a nucleoside 5'- a [phospholipid]- ACP beta-hydroxyacyl- a (5Z)-dodec- (R)-3-amino-2- AMP 5'-phosphate a peptide an alcohol diphosphate reductase: fabI-3 KVU_1714 nucleoside triphosphate α-D- dGMP in tRNA monophosphate dihydrosterculate synthase: fabB (Acyl-carrier- 5-enoyl-[acp] methylpropanoate Purine and other pyrophosphohydrolase: an [HPr protein]- D-glucopyranose a protein with an laurate glucopyranose 6 γ [+ 3 isozymes] protein) cytidine phosphorylase, N π -phospho- pyruvate 3-nonaprenyl-4- N -( -glutamyl)- a 12-methyltridecanoyl-[acp] KVU_1153 SAICAR 1-phosphate Long-chain- dehydratase family 1: KVU_2323 dUTP dUMP L-histidine hydroxybenzoate L-lysine crosslink FabZ: fabZ adenine a 3-oxotetradecanoyl- fatty-acid-- stearate biosynthesis S-methyl-5'-thioadenosine acetaldehyde DHAP II (bacteria and plants) [acp] CoA ligase: a (2E,12S)-12- 3-oxoacyl-ACP degradation II all-trans- all-trans- KVU_1613 methyltetradec-2-enoyl-[acp] 5-hydroxy-CTP 5-hydroxy-CMP lysine within maltohexaose a [lipoyl-carrier L-iditol an N-carbamoyl- a D-hexose short-chain synthase: fabB an octanoyl-[acp] decaprenyl heptaprenyl (R)-lipoate 2-phosphoglycolate Ins(4)P acetaldehyde histidinol S-methyl-5'- gcv protein H 4-hydroxybenzoate 4-hydroxybenzoate protein]-L-lysine dATP L-amino acid dehydrogenase: enoyl-(Acyl- [+ 3 isozymes] a palmitoyl-[acp] diphosphate diphosphate sorbitol phosphoglycolate aldehyde lauroyl-CoA 12-methyltridecanoate 3-oxoacyl- thioadenosine5'-methylthioadenosine myo-inositol-1(or 4) N-carbamoyl- histidinol glucokinase: KVU_2131 carrier-protein) enoyl-ACP mazG family protein: mazG dehydrogenase: sldC phosphatase: dehydrogenase ACP phosphorylase (MtnP- alpha amylase -monophosphatase beta-alanine dehydrogenase glk [+ 5 isozymes] reductase: fabI-2 reductase: fabI-3 lipoate-protein nucleoside triphosphate sorbitol KVU_0980 (NADP+): a 14-methyl-3- synthase: fabB like protein): KVU_0318 lipoyltransferase: 4-hydroxybenzoate 4-hydroxybenzoate catalytic protein: suhB amidohydrolase 3: hisD a (3R)-3- polyprenyltransferase: polyprenyltransferase: ligase A: lplA pyrophosphohydrolase: dehydrogenase: sldC [+ 2 isozymes] KVU_0810 enoyl-ACP oxopentadecanoyl-[acp] 5-MTR-1-P Carboxylate Degradation KVU_1974 region: aglA [+ 2 isozymes] protein: amaB D-hexose 6- hydroxytetradecanoyl- a 3-oxooctadecanoyl-[+ 3 isozymes] ubiA ubiA KVU_1153 keto-L-sorbose glycolate acetate his reductase: fabI-3 short-chain myo-inositol an L-amino acid phosphate [acp] [acp] a [glycine-cleavage dAMP a (12S)-12- dehydrogenase: D-glucosaminate degradation a [lipoyl-carrier protein]- beta- 2-methylcitrate cycle I pyruvate decarboxylation to acetyl CoA I D-gluconate complex H protein] D-glucopyranose maltopentaose hydroxyacyl- methyltetradecanoyl-[acp] KVU_2131 palmitoleate short-chain acyl-carrier protein 3-decaprenyl-4- 3-heptaprenyl-4- N 6 -lipoyl-L-lysine biosynthesis I (from dehydrogenase: degradation N 6 -octanoyl-L-lysine (Acyl-carrier- [+ 5 isozymes] 2-amino-2-deoxy- a [pyruvate hydroxybenzoate hydroxybenzoate (5Z)-dodec-5-enoate) KVU_2131 propanoate protein) 3-oxoacyl-ACP a (3R)-3-hydroxy-14- Detoxification D-gluconate dehydrogenase D-gluconate [+ 5 isozymes] pyruvate dehydratase a (5Z)-dodec- phosphoenolpyruvate- E2 protein] N 6 thermoresistant synthase: fabB methylpentadecanoyl-[acp] a (3R)-3- propanoate:CoA UDP-N-acetyl-α-D-glucosamine undecaprenyl-diphospho-N all-trans- a 2,3,4-saturated α 31-O- a cis-delta19- L-malic pyridoxamine FabA: fabA 5-enoyl-[acp] dependent sugar pyruvate γ maltoheptaose a 9S rRNA a (1->4)- -D-glucan pyruvate [+ 3 isozymes] (12S)-12- 3-oxoacyl- hydroxyoctadecanoyl- ligase (AMP- -lipoyl-L-lysine gluconokinase- -acetylmuramoyl-L-alanyl- - 4-hydroxybenzoate hexaprenyl 1,2-diacyl-sn- desmethylFK-506 Ins(5)P 37-methoxy-38- semialdehyde beta-hydroxyacyl- arsenate phosphotransferase pyruvate dehydrogenase CTP GTP 1,4-alpha-glucan 5'-phosphate beta- methyltetradecanoate ACP [acp] reactive oxygen species degradation forming): like protein: gntK D-glutamyl-L-lysyl- D-alanine diphosphate glycerol 3-phosphate methyltransferase myo-inositol-1(or 4) methyl-C57:1-[acp]cyclopropane- aldehyde pyruvate (Acyl-carrier-protein) detoxification system, EIIA 2: ptsN dehydrogenase (Acetyl- mazG family protein: mazG branching enzyme pyridoxamine hydroxyacyl- synthase: fabH beta- KVU_1477 gluconate alpha amylase FkbM: KVU_0840 -monophosphatase fatty-acyl- dehydrogenase carboxylase a (14S)-14-methyl-3- dehydratase II (glutaredoxin) complex, E2 transferring) D-inositol-3-phosphate nucleoside triphosphate (Alpha amylase 5''-phosphate (Acyl-carrier- [+ 3 isozymes] hydroxyacyl- PTS system kinase 2; 4-hydroxybenzoate phosphatidate catalytic ribonuclease methyltransferase protein: suhB phospholipid (NADP+): protein: pyc oxohexadecanoyl-[acp] FabA: fabA a (7Z)-3-oxotetradec- arsenate superoxide component, : KVU_0669 glycosyltransferase: pyrophosphohydrolase: protein): glgB oxidase: pdxH protein) (Acyl-carrier- fructose propanoyl-CoA gluconate polyprenyltransferase: cytidylyltransferase: region: aglA E: rne FkbM: KVU_2019 synthase: cfa KVU_0810 short-chain beta-hydroxyacyl- 7-enoyl-[acp] Arsenate dihydrolipoamide murG KVU_1153 [+ 2 isozymes] oxaloacetate dehydratase protein) Superoxide dismutase: sodM subfamily [+ 2 isozymes] transport, ubiA cdsA a GlgE-glycogen FK-506 a cis-methoxy- (S)-malate PLP dehydrogenase: (Acyl-carrier-protein) reductase: acetyltransferase: myo-inositol FabZ: fabZ short-chain dehydratase superoxide transporter GNT I GMP C59-meroacyl-[acp] KVU_2131 dehydratase arsC-2 pdhB ditrans,octacis-undecaprenyldiphospho- UDP dehydrogenase: FabA: fabA dismutase, Fe: sodB subunit IIA: pyruvate a [pyruvate system: idnK N-acetyl-(N-acetylglucosaminyl)muramoyl- D-glucopyranose maltohexaose a 5S rRNA an rRNA fragment a (2E)-tetradec- [+ 5 isozymes] FabZ: fabZ a [pyruvate D-gluconate 3-hexaprenyl-4- a CDP-2,3,4-saturated- KVU_PA0057 Arsenate KVU_2564 (2S,3S)-2- [+ 2 isozymes] dehydrogenase dehydrogenase L-alanyl-γ-D-glutamyl-L-lysyl-D-alanine 2-enoyl-[acp] beta- dehydrogenase 6 hydroxybenzoate diacylglycerol a (3R,14S)-3-hydroxy-14- a (2E)-14-methylpentadec- [+ 5 isozymes] reductase hydrogen peroxide methylcitrate complex, E2 E2 protein] N -S- 6-phosphate E2 protein] N 6 - enoyl-ACP 2-enoyl-[acp] a (3R,7Z)-3- hydroxyacyl- and related 2-amino-2-deoxy-D- component, acetyldihydrolipoyl- methylhexadecanoyl-[acp] 2-methylcitrate dihydrolipoyl-L-lysine reductase: hydroxytetradec- (Acyl-carrier- protein: gluconate 6-phosphate dihydrolipoamide L-lysine UDP-N-acetyl- decaprenyl-diphospho-N- DNA combined with beta-hydroxyacyl- enoyl-(Acyl- Catalase domain dehydratase: 37 maltopentaose a nucleoside an organic UDP fabI-3 7-enoyl-[acp] protein) KVU_0327 acetyltransferase: α-D-glucosamine acetylmuramoyl-pentapeptide DMAPP an adenosine exogenous DNA to form N,N'-diacetylchitobiose L-cysteate Ins(1)P [DNA] an aldehyde glycolate (Acyl-carrier- carrier-protein) enoyl-ACP dehydratase protein: katE prpD in tRNA triphosphate hydroperoxide ribonucleoside- beta- arsenite pdhB a recombinational junction nucleoside triphosphate glycoside aspartate Type I aldehyde protein) reductase: fabI-2 reductase: fabI-3 FabZ: fabZ catalase/peroxidase cis-2- Holliday junction alkylhydroperoxidase myo-inositol-1(or 4) diphosphate hydroxyacid a myristoyl-[acp] hydroxyacyl- H O hydroxyl radical D-inositol-3-phosphate pyrophosphohydrolase: hydrolase family 3 aminotransferase restriction- dehydrogenase dehydratase HPI: katA 2 methylaconitate DNA helicase alpha amylase AhpD core protein: -monophosphatase reductase class oxidase 1: enoyl-ACP (Acyl-carrier- glycosyltransferase: tRNA delta(2)- domain-containing protein: KVU_0981 mod: hsdS (NADP+): FabA: fabA a (2E)-octadec- KDGP acetate subunit RuvB: ruvB catalytic KVU_1153 KVU_PB0174 protein: suhB Ib glutaredoxin: KVU_2484 3-oxoacyl- reductase: fabI-3 protein) murG isopentenylpyrophosphate protein: KVU_0011 [+ 2 isozymes] KVU_0810 2-enoyl-[acp] conversion Crossover junction region: aglA mazG family [+ 4 isozymes] [+ 2 isozymes] a double stranded nrdH nrdE nrdF ACP beta-hydroxyacyl- dehydratase O transferase: miaA [+ 2 isozymes] an alcohol glyoxylate enoyl-ACP 2 to acetyl-CoA protein: mazG 3-sulfopyruvate DNA with 5'- a carboxylate synthase: fabB (Acyl-carrier- a 14-methylpentadecanoyl-[acp] FabA: fabA arsenite 2-dehydro-3- acetyl-CoA endodeoxyribonuclease myo-inositol dUDP reductase: (2R,3S)-2- decaprenyl-pyrophosphoryl- a nucleoside 5'- N-acetyl-D-glucosamine terminal phosphate [+ 3 isozymes] protein) deoxyphosphogluconate acetate UDP resolution of recombinationalruvC: ruvC a (2E,7Z)-tetradeca- methylisocitrate 6 37 D-glucopyranose maltotetraose monophosphate fabI-3 (N-acetylglucosamine)-N- N -dimethylallyladenosine junction formation a 3-oxohexadecanoyl- dehydratase 2,7-dienoyl-[acp] aldolase/4-hydroxy-2- acetate-CoA acetylmuramyl-(pentapeptide) in tRNA of two intact strands [acp] FabZ: fabZ a stearoyl-[acp] oxoglutarate aldolase 2-methylisocitrate ligase, AMP- enoyl-ACP fatty acid elongation -- saturated subfamily protein: eda dependent: a (2E,14S)-14- lyase: prpB short-chain 14-methylpentadecanoate reductase: KVU_1477 3-(4- an N-acyl-D- methylhexadec-2-enoyl-[acp] γ-glutamyl-p- an isoprenoid N,N',N''- a 5-aminomethyl-2- a uracil 1939 5-α-androstan- a [phospholipid]- dCDP (5R)-5-benzyl- dehydrogenase: fabI-3 D-glyceraldehyde acetyl-CoA glycyl-glycine hydroxyphenyl) glucosamine Ins(2)P wound RNA pyruvate pyruvate succinate nitroanilide 4-hydroxybenzoate diphosphate triacetylchitotriose thiouridine 34 in tRNA in 23S rRNA 3β,17β-diol palmitoleate ribonucleoside- hydantoin KVU_2131 enoyl-(Acyl- a (7Z)-tetradec- an acetoacetyl-[acp] 3-phosphate pyruvate tRNA(5- 6-phosphate DTDP-4- cyclopropane- ATP- 23S rRNA (uracil-5- myo-inositol-1(or 4) diphosphate hydantoin [+ 5 isozymes] carrier-protein) enoyl-ACP 7-enoyl-[acp] 4-hydroxyphenylpyruvate methylaminomethyl- N-acetylmannosamine- dehydrorhamnose fatty-acyl- dependent a (3R)-3- reductase: fabI-3 stearate Gamma- beta-N- dioxygenase 6-phosphate )-methyltransferase -monophosphatase reductase class racemase: reductase: fabI-2 3-oxoacyl- 4-hydroxybenzoate 2-thiouridylate) 3,5-epimerase, phospholipid RNA hydroxyhexadecanoyl- glutamyltranspeptidase: acetylhexosaminidase protein: KVU_2376 epimerase: nanE RumA: rumA protein: suhB Ib glutaredoxin: hyuE enoyl-ACP Long-chain- polyprenyltransferase: methyltransferase: α 1939 putative: galE1 synthase: cfa helicase: rhlE [acp] gondoate biosynthesis ACP KVU_1845 protein: KVU_2472 an N-acyl- -D- a 5-methyluracil β α [+ 2 isozymes] a [phospholipid]-8- nrdH nrdE nrdF (5S)-5-benzyl- reductase: fabI-3 fatty-acid-- ubiA homogentisate mnmA 17- -hydroxy-5- - beta- (anaerobic) synthase: fabH [+ 2 isozymes] mannosamine in 23S rRNA myo-inositol (2-hexylcyclopropyl) an unwound RNA hydantoin CoA ligase: a 3-oxoacyl-[acp] a 5-methylaminomethyl- androstan-3-one CDP hydroxyacyl- [+ 3 isozymes] 34 6-phosphate octanoate a (14S)-14- KVU_1613 γ-L-glutamyl- 2-thiouridine in tRNA (Acyl-carrier- 4-nitroaniline a 4-hydroxy-3- methylhexadecanoyl-[acp] a malonyl-[acp] an oleoyl-[acp] a (9Z)-3-oxohexadec- glycylglycine N,N'- N-acetyl-D- protein) 9-enoyl-[acp] stearoyl-CoA polyprenylbenzoate diacetylchitobiose glucosamine dehydratase long-chain short-chain FabA: fabA 3-oxoacyl-ACP fatty acid dehydrogenase: short-chain 10 a ribonucleoside 2457 RNase E (14S)-14- synthase: fabH AICAR an N - RNase R degradation 3-phenyl-2- 2-dehydro-3-deoxy- 7,8-dihydropterin uridine 1,6-anhydro-N- a [protein]- phosphoenol beta- epoxysqualene activation KVU_2131 dehydrogenase: formyltetrahydrofolate UDP-N-acetyl-α-D- D-glt substrate RNA oxopropanoate D-galactonate 2',3'-cyclic in 23S rRNA Ins(6)P acetyl-β-muramate degradation L-glutamine pyruvate methylhexadecanoate [+ 3 isozymes] hydroxyacyl- biosynthesis a long-chain [+ 5 isozymes] KVU_PA0057 muramoyl-L-alanine 4-hydroxyphenylpyruvate 2-dehydro-3- phosphate ribosomal myo-inositol-1(or 4) anhydro-N- substrate mRNA chemoreceptor pyruvate (Acyl-carrier- fatty acid a (3R,9Z)-3- 3-oxoacyl-ACP 2',3'-cyclic-nucleotide Chlorohydrolase large subunit acetylmuramic glutamine Long-chain- [+ 5 isozymes] dioxygenase deoxygalactonokinase: -monophosphatase ribonuclease kinase: protein) (2E,6E)-farnesyl hydroxyhexadec- synthase: fabH phosphoribosylaminoimidazolecarboxamide ribonuclease 2'-phosphodiesterase: family protein: guaD pseudouridine acid kinase deamidase an (11Z)-3-oxo- fatty-acid-- UDP-N- protein: KVU_2376 dgoK protein: suhB E: rne pykA dehydratase diphosphate icos-11-enoyl-[acp] 9-enoyl-[acp] [+ 3 isozymes] formyltransferase / IMP cyclohydrolase: purH R: rnr 2-dehydro-3-deoxy- cpdB synthase D: rluD 2: anmK CheD: cheD phytoene/ a 2,3,4-saturated a (3R)-3-hydroxyacyl- acetylmuramoylalanine-- (2-hydroxyphenyl) 7,8- 2457 [+ 2 isozymes] N-acetyl-D- FabZ: fabZ CoA ligase: beta- beta-hydroxyacyl- a ribonucleoside a pseudouridine a [protein]-α- pyruvate squalene acyl-CoA hydrolysis fatty acyl-[acp] [acyl-carrier protein] D-glutamate ligase: murD acetate D-galactonate dihydrolumazine muramate 6- an mRNA fragment short-chain a long-chainKVU_1613 hydroxyacyl- (Acyl-carrier- 3'-phosphate in 23S rRNA myo-inositol L-glutamate synthetase: 6-phosphate phosphate a (2E)-hexadec- dehydrogenase: fatty acyl-CoA (Acyl-carrier- protein) a nucleoside 5'- 2-enoyl-[acp] KVU_0582 a 2,3,4-saturated KVU_PA0057 FAICAR a tetrahydrofolate UDP-N-acetyl-α-D-muramoyl- a diribonucleotide presqualene fatty acyl CoA protein) dehydratase monophosphate enoyl-ACP diphosphate putative [+ 5 isozymes] dehydratase FabZ: fabZ L-alanyl-D-glutamate esterase/lipase/ reductase: phytoene/ a (3R,11Z)-3-hydroxy- FabA: fabA beta-hydroxyacyl- fabI-3 thioesterase: guanosine 2604 2,5-diamino-6-(5- squalene icos-11-enoyl-[acp] (Acyl-carrier- 5-amino-4- + 2-hydroxychromene- 3-demethylubiquinol- 1-carboxyvinyl a uridine KVU_PB0175 a (2E,9Z)-hexadeca- PRPP NAD(P)H a plastoquinone H an aryl sulfate a phenol 2',3'-cyclic a quinone phospho-D-ribitylamino) asp cobyrinate glyoxylate synthetase: beta-hydroxyacyl- 2,9-dienoyl-[acp] protein) imidazolecarboxyamide 2-carboxylate 10 carboxyphosphonate in 23S rRNA a palmitoyl-[acp] putative dehydratase 2-hydroxychromene- 3-demethylubiquinone- monophosphate 2,3- ribosomal NADPH:quinone pyrimidin-4(3H)-one Cobyrinic acid malate KVU_0582 (Acyl-carrier- 2',3'-cyclic-nucleotide riboflavin L-aspartate esterase/lipase/ enoyl-ACP enoyl-ACP FabA: fabA 2-carboxylate 9 3-methyltransferase: dimethylmalate large subunit reductase protein: ac-diamide synthase protein) NAD(P)H aryl-sulfate 2'-phosphodiesterase: biosynthesis dehydrogenase squalene thioesterase;acyl- reductase: reductase: fabI-3 adenine isomerase: nahD ubiG lyase: prpB pseudouridine KVU_1793 synthase: G: glcB dehydratase a 2,3,4-saturated a trans-2-enoyl- dehydrogenase sulfotransferase: cpdB protein 3: KVU_1272 coa thioester fabI-3 fatty acyl-[acp] enoyl-(Acyl- [acyl-carrier protein] phosphoribosyltransferase: apt trans-O- synthase D: rluD [+ 2 isozymes] RibD: ribD KVU_PA0047 FabA: fabA protein: KVU_1632 KVU_1120 ubiquinol-10 carboxyphosphinopyruvate a pseudouridine 2604 cob(II)yrinate (S)-malate hydrolase protein: carrier-protein) hydroxybenzylidenepyruvate 3'-GMP a semiquinone 5-amino-6-(5-phospho- oxaloacetate palmitate KVU_PA0186 a (2E,11Z)-icosa- a palmitoleoyl-[acp] reductase: fabI-2 in 23S rRNA D-ribitylamino)uracil a,c-diamide (3S)-2,3- a 2,3,4-saturated 2,11-dienoyl-[acp] AICAR a plastoquinol NAD(P) + an aryl sulfate a phenol Long-chain- epoxy-2,3- fatty acid fatty-acid-- dihydrosqualene enoyl-ACP enoyl-ACP CoA ligase: reductase: fabI-3 reductase: fabI-3 adenosine 10 KVU_1613 palmitoleate + (4S)-4-hydroxy-2- a 3- 4a-hydroxy-N - α an (S)-2- a dihydroceramide UDP-α-D-glucose phylloquinone NAD(P)H H carboxynorspermidine carboxyphosphinopyruvate D-glucopyranose -amylose (R)-lactate GDP-β-L-fucose a gondoyl-[acp] oxoheptanedioate demethyubiquinol 2',3'-cyclic formyltetrahydrofolate hydroxycarboxylate palmitoyl-CoA carboxynorspermidine 3-demethylubiquinone- monophosphate 2,3- xylose isomerase Pterin-4-alpha- 1,4-alpha-glucan hydroxyacid D-2-hydroxyacid Fucose 2',3'-cyclic-nucleotide decarboxylase 9 3-methyltransferase: dimethylmalate domain-containing carbinolamine branching enzyme oxidase 1: dehydrogenase: synthetase Nucleoside and Nucleotide Biosynthesis ceramide NAD(P)H HpcH/HpaI aldolase 2'-phosphodiesterase: protein: nspC ubiG lyase: prpB protein: KVU_1355 dehydratase (Alpha amylase KVU_2484 KVU_1352 Fcl: fcl glucosyltransferase: dehydrogenase /citrate lyase cpdB protein): glgB 3-(hydroxyphosphinoyl) [+ 4 isozymes] 2: phhB a 2-oxo GDP-4-dehydro- KVU_1102 protein: KVU_1632 family protein: hpaI norspermidine UQH an N 10 -formyl- pyruvate α-D-rhamnose superpathway of pyrimidine 2 3'-AMP pyruvate keto-D-fructose amylopectin carboxylate UMP biosynthesis II superpathway of guanosine superpathway of superpathway of pyrimidine adenine and adenosine salvage III adenine salvage adenine and adenosine salvage II pyrimidine 7,8-dihydrofolate ribonucleotides de novo biosynthesis nucleotides de novo biosynthesis I CMP adenosine nucleotides deoxyribonucleoside salvage nucleobases salvage II a β-D-glucosyl-N UDP de novo biosynthesis I phosphorylation NAD(P) + phylloquinol pyruvate succinate semialdehyde cytosine -acylsphinganine gln hydrogencarbonate gln hydrogencarbonate 2'-deoxycytidine adenine IMP CMP adenine adenosine aminohydrolase IMP inosine guanosine and asp cytidine cytidylate inosine-uridine preferring protein: codAb kinase: cmk xanthosine phosphorylase nucleoside hydrolase UDP-N-acetyl-α-D-glucosamine undecaprenyl-diphospho-N-acetylmuramoyl-L- dTTP (R)-3- a pyrimidine base carbamoyl phosphate carbamoyl IMP deaminase [+ 2 isozymes] γ a peptidoglycan a cytosine in DNA 3-demethylubiquinol-9 butan-2-one a double stranded DNA chloroacetaldehyde (S)-ureidoglycolate D-gluconate CDP family protein: deoD adenine adenine deaminase 2: ade transmembrane uracil alanyl- -D-glutamyl-L-lysyl- D-alanyl-D-alanine mazG family protein: mazG hydroxybutanoate lesion in DNA synthetase, glutamine phosphate dehydrogenase/ 1, 2, 7: cdd dCMP adenosine modification methylase N-methylhydantoinase aldehyde choline adenylosuccinate nucleoside phosphoribosyltransferase: apt [+ 2 isozymes] protein: KVU_2259 3-demethylubiquinone- nucleoside triphosphate Helicase, ATP- 3-hydroxybutyrate DNA amidotransferase synthetase, GMP reductase, uracil D-inositol-3-phosphate (Cytosine-specific B/acetone dehydrogenase ureidoglycolate dehydrogenase: synthetase: purA cytidylate diphosphate [+ 4 isozymes] 9 3-methyltransferase: pyrophosphohydrolase: dependent: dehydrogenase: glycosylase: small subunit: carA glutamine transglutaminase- 2'-deoxyuridine phosphoribosyltransferase: glycosyltransferase: murG lysozyme: methyltransferase) carboxylase subunit (NADP+): hydrolase: allA KVU_PB0008 kinase: cmk kinase adenine KVU_0752 ubiG KVU_1153 KVU_0108 KVU_1273 mutM amidotransferase like protein: adenosine deaminase: add KVU_1721 : KVU_0243 alpha: KVU_PB0142 KVU_0810 2-keto-D- Thymidine superfamily AMP hypoxanthine an apyrimidinic asp small subunit: carA KVU_0087 adenylo-succinate dCDP modification methylase ubiquinol-9 dTMP 3-oxopentanoate a 5'-phosphooligonucleotide acetoacetate 2-chloroacetate glyoxylate gluconate carbamoyl phosphate kinase: tdk protein: ndk UMP ditrans,octacis-undecaprenyldiphospho-N- UDP site in DNA inosine-5'- adenine N-acetyl-D- a N-acetylmuramoyl- XorII: KVU_0254 adenylosuccinate nucleoside xanthine acetyl-(N-acetyl-β-D-glucosaminyl)muramoyl-L- carbamoyl monophosphate thymidine CTP inosine phosphoribosyltransferase: apt glucosamine pentapeptide- asp lyase protein: purB dUMP diphosphate phosphoribosyltransferase: gpt alanyl-γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine a 5-methylcytosine in DNA aspartate phosphate dehydrogenase: kinase diphosphoundecaprenol hypoxanthine carbamoyltransferase guaB Thymidine superfamily inosine guanosine and AMP phosphoribosyltransferase: hpt catalytic subunit: argD aspartate AMP kinase: tdk protein: ndk xanthosine phosphorylase a sphingosine CTP succinate a uridine 32 aspartate carbamoyltransferase XMP family protein: deoD guanine and guanosine salvage UDP-α-D-glucose penicillin G 3-demethylubiquinol-6 a ribonucleoside a double stranded DNA coniferaldehyde D-gluconate citrate dCTP IMP IMP ceramide mazG family protein: mazG 3'-phosphate semialdehyde in tRNA carbamoyltransferase catalytic subunit: argD adenylate kinase ribosomal Dehydrogenase hypoxanthine 3-demethylubiquinone- nucleoside triphosphate 2',3'-cyclic-nucleotide 4-hydroxybutyrate DNA gyrase aldehyde aconitate catalytic: KVU_0140 pyrB aspartate bifunctional GMP (ATP-AMP dTMP 9 3-methyltransferase: dehydrogenase subunit A: gyrA large subunit dehydrogenase: cytochrome c hydratase 1: synthase/glutamine transphosphorylase) guanosine phosphoribosylaminoimidazolecarboxamide ceramide pyrophosphohydrolase: 2'-phosphodiesterase: carbamoyltransferase penicillin amidase ubiG GbD: gbd [+ 4 isozymes] pseudouridine KVU_1397 subunit: gadh2 KVU_0869 amidotransferase protein: adk thymidylate xanthine inosine guanosine and formyltransferase / IMP cyclohydrolase: purH glucosyltransferase: KVU_1153 cpdB catalytic: KVU_0140 pyrB family protein: acy a negatively synthase D: rluD 2-keto-D- N-carbamoyl-L-aspartate protein: guaA kinase: tmk phosphoribosyltransferase: gpt xanthosine phosphorylase KVU_1102 ubiquinol-6 CMP a ribonucleoside 4-hydroxybutanoate a pseudouridine 32 ferulate D-threo-isocitrate FAICAR supercoiled DNA gluconate ADP hypoxanthine family protein: deoD in tRNA N-carbamoyl- dTDP superpathway of pyrimidine guanine aspartate GMP pyrimidine deoxyribonucleotides de novo biosynthesis III phosphoribosyltransferase: hpt a β-D-glucosyl-N UDP L-aspartate nucleoside nucleobases salvage 6-aminopenicillanate phenylacetate transcarbamoylase, ribonucleoside- -acylsphingosine diphosphate xanthine PyrC subunit: KVU_0140 aspartate Guanylate diphosphate UDP CTP IMP uracil kinase ribonucleoside- Ham1-like protein: uracil phosphoribosyltransferase: gpt [+ 2 isozymes] transcarbamoylase, kinase: reductase class α superfamily KVU_2242 phosphoribosyltransferase: UTP D-sedoheptulose 1-carboxyvinyl (2R,3S)-3- -D- PyrC subunit: KVU_0851 Ib glutaredoxin: diphosphate reductase hypoxanthine phosphatidylglycerolphosphate a ceramide UDP-α-D-glucose a penicillin 3-demethylubiquinol-7 3'-UMP 5-methylcytosine reduced riboflavin (S)-dihydroorotate protein: ndk class Ib glutaredoxin: CDP KVU_1721 phosphoribosyltransferase: hpt (1-oleoyl, 2-palmitoyl) mazG family protein: mazG 7-phosphate carboxyphosphonate isopropylmalate galactopyranose KVU_0140 nrdH nrdE nrdF UMP 3-demethylubiquinone- 2',3'-cyclic-nucleotide 2,3- 3-isopropylmalate aminohydrolase FMN GDP dTTP nrdH nrdE nrdF ribonucleoside- superpathway of 5-aminoimidazole nucleoside triphosphate phosphoheptose 2'-phosphodiesterase: galactokinase: dihydroorotate [+ 2 isozymes] dUDP phosphatidylglycerophosphatase: 9 3-methyltransferase: dimethylmalate dehydrogenase: protein: codAb reductase: diphosphate reductase ribonucleotide biosynthesis cytidylate kinase: cmk GMP ceramide pyrophosphohydrolase: isomerase 2: gmhA cpdB lmbP oxidase A: pyrD dADP pgpA penicillin amidase ubiG lyase: prpB leuB [+ 2 isozymes] KVU_1212 (S)-dihydroorotate nucleoside diphosphate class Ib glutaredoxin: Uridylate kinase: pyrH glucosyltransferase: KVU_1153 α PRPP 1-oleoyl-2-palmitoyl- family protein: acy D-glycero-D-manno- uridine 3-(hydroxyphosphinoyl) 4-methyl-2- thymine -D-galactose orotate nucleoside ribonucleoside- nucleoside kinase superfamily nrdH nrdE nrdF PRPP UDP guanine and guanosine salvage II KVU_1102 ubiquinol-7 UMP 1-phosphate riboflavin dihydroorotase, phosphatidylglycerol heptose 7-phosphate pyruvate oxopentanoate diphosphate diphosphate diphosphate protein: ndk dCDP amidophosphoribosyltransferase homodimeric nucleoside orotate kinase reductase class kinase superfamily putative: purF UDP type: pyrC dUTP nucleoside diphosphate 5-phospho-β- diphosphate kinase a glucosylceramide 6-aminopenicillanate a carboxylate phosphoribosyltransferase: superfamily Ib glutaredoxin: protein: ndk guanosine pyrE mazG family protein: mazG kinase superfamily D-ribosylamine superfamily protein: ndk dihydroorotate protein: ndk nrdH nrdE nrdF inosine-uridine preferring adenine and adenosine salvage I oxidase A: pyrD nucleoside triphosphate protein: ndk phosphoribosylamine- dATP UTP nucleoside hydrolase a (1->6)- a 2-deoxystreptamine cytidine 2',3'-cyclic uridine 2'3'-cyclic PRPP pyrophosphohydrolase: glycine ligase α 3'-cmp β orotate dCTP transmembrane α a (1->4)- -D-glucan a uridine in tRNA monophosphate monophosphate a -D-galactoside hydroxypyruvate 5-fluorocytosine D-sedoheptulose D-ribulose orotidine 5'-phosphate KVU_1153 protein: purD CTP synthase: pyrG -D-glucan antibiotic GTP dGDP xanthine and xanthosine salvage protein: KVU_2259 adenosine TRNA-dihydrouridine aminoglycoside N3`- 2',3'-cyclic-nucleotide 2',3'-cyclic-nucleotide 2',3'-cyclic-nucleotide acetyltransferase hydroxypyruvate aminohydrolase carbohydrate carbohydrate dUMP cycloisomaltooligosaccharide 2'-phosphodiesterase: 2'-phosphodiesterase: 2'-phosphodiesterase: Orotidine 5'-phosphate orotate pyrimidine GAR CTP [+ 4 isozymes] inosine guanosine and synthase: KVU_0800 acetyltransferase (Isoleucine patch isomerase: protein: codAb kinase, kinase FGGY: glucanotransferase: KVU_1022 alpha amylase cpdB cpdB cpdB decarboxylase: pyrF phosphoribosyltransferase: nucleoside Thymidylate ribonucleosides guanine xanthosine phosphorylase tRNA-dihydrouridine protein: aacC superfamily): lacA KVU_1235 [+ 2 isozymes] PfkB: cscK KVU_0490 pyrE family protein: deoD catalytic region: aglA synthase A: KVU_2218 an N 3 -acetyl-2- cytidine a 6-acetyl-β- D-sedoheptulose D-ribulose UMP diphosphate xanthosine synthase (FAD): thyX salvage II a cycloisomaltooligosaccharide 3'-cmp 3'-UMP tartronate 5-fluorouracil cytidine xanthine adenine deoxystreptamine antibiotic D-galactoside 1-phosphate 5-phosphate kinase inosine guanosine and dTMP a 5,6-dihydrouridine in tRNA semialdehyde cytidylate kinase: cmk orotidine 5'- cytidine deaminase phosphoribosyltransferase: gpt superfamily xanthosine phosphorylase α Uridylate kinase: pyrH 1, 2, 7: cdd FGAR hypoxanthine a (1->4)- -D-glucan D-glucopyranose phosphate protein: ndk family protein: deoD thymidylate kinase: tmk adenine xanthine uridine phosphoribosyltransferase: hpt UDP Orotidine 5'- phosphoribosylformylglycinamidine phosphoribosyltransferase: apt dGTP dTDP inosine/uridine- phosphate synthase subunit II: KVU_1665 nucleoside xanthine preferring nucleoside GMP decarboxylase: nucleoside diphosphate [+ 3 isozymes] diphosphate kinase phosphoribosyltransferase: gpt hydrolase: KVU_0571 AMP superfamily protein: ndk pyrF kinase superfamily gln protein: ndk [+ 3 isozymes] FGAM UTP UMP XMP dTTP uracil CTP synthase: pyrG AIR CTP

an an an an an an 2-amino-2- 2-amino-2- oligopeptide oligopeptide oligopeptide oligopeptide oligopeptide oligopeptide a ferric a ferric a ferric a ferric a ferric a ferric iron(III)- iron(III)- phosphonate a branched- a branched- deoxy-D- deoxy-D- L-alanyl-γ-D- L-alanyl-γ-D- L-alanyl-γ-D- L-alanyl-γ-D- L-alanyl-γ-D- L-alanyl-γ-D- L-alanyl-γ-D- L-alanyl-γ-D- L-alanyl-γ-D- L-alanyl-γ-D- 2+ 2+ 2+ 2+ a polar a polar 2+ 2+ 2+ Ni an an Ni an Ni Ni an an an an an an an an hydroxamate hydroxamate hydroxamate hydroxamate hydroxamate hydroxamate enterobactin iron(III) dicitrate iron(III) dicitrate iron(III) dicitrate iron(III) dicitrate iron(III) dicitrate enterobactin 3,5- 3,5- a C4- a C4- α-L- chain chain a dicarboxylate gluconate 6- gluconate 6- a dicarboxylate a dicarboxylate a dicarboxylate a dicarboxylate a dicarboxylate glutamyl-meso- glutamyl-meso- glutamyl-meso- glutamyl-meso- glutamyl-meso- glutamyl-meso- glutamyl-meso- glutamyl-meso- glutamyl-meso- glutamyl-meso- an an Ni an an an an an Ni an Ni an an malonate malonate malonate a carbohydrate phosphonate amino acid amino acid D-gluconate D-gluconate a dipeptide a dipeptide an oligopeptide oligopeptide oligopeptide an oligopeptide oligopeptide an oligopeptide an oligopeptide oligopeptide oligopeptide oligopeptide oligopeptide oligopeptide oligopeptide oligopeptide oligopeptide complex complex complex complex complex complex complex iron(III)-enterobactin complex iron(III)-enterobactin complex iron(III)-enterobactin complex iron(III)-enterobactin complex iron(III)-enterobactin complex complex dimethoxytoluene dimethoxytoluene dicarboxylate dicarboxylate arabinopyranose α-L- amino acid amino acid a capsular a capsular dCTP phosphate phosphate dCTP dCTP dCTP dCTP dCTP diaminopimelate diaminopimelate diaminopimelate diaminopimelate diaminopimelate diaminopimelate diaminopimelate diaminopimelate diaminopimelate diaminopimelate oligopeptide oligopeptide an oligopeptide oligopeptide oligopeptide oligopeptide oligopeptide oligopeptide an oligopeptide oligopeptide an oligopeptide oligopeptide oligopeptide polysaccharide polysaccharide a carbohydrate predicted predicted predicted predicted predicted predicted arabinopyranose ABC ABC ABC ABC ABC ABC predicted ABC KVU_1401 KVU_1402 KVU_0928 KVU_1428 KVU_0935 PB0125 KVU_0277 transporter transporter transporter transporter transporter transporter KVU_1990 PB0145 PB0146 PB0148 KVU_0967 KVU_0968 PB0162 KVU_0428 KVU_2386 KVU_1975 KVU_0039 KVU_0259 PA0233 PA0163 KVU_0482 PB0046 KVU_0770 PA0161 KVU_0259 PA0163 KVU_0482 PB0046 KVU_0770 KVU_0001 transporter of KVU_1883 KVU_0916 KVU_2380 KVU_1302 KVU_1426 KVU_2502 PB0195 KVU_1376 KVU_1228 KVU_2451 KVU_1359 KVU_0111 PA0157 PB0098 KVU_0681 KVU_2192 KVU_2564 KVU_2496 KVU_2379 KVU_2036 KVU_2385 KVU_0680 KVU_0679 KVU_1350 KVU_0675 KVU_1402 KVU_0928 PB0145 PB0146 KVU_0967 KVU_0968 KVU_0430 PA0254 PB0034 KVU_0936 KVU_0430 PA0254 PA0256 PB0183 KVU_0562 KVU_0320 PB0018 PA0084 PB0032 PB0033 PB0034 KVU_0936 PB0064 KVU_0566 PA0179 of an of an of an of an of an of an phosphonate oligopeptide oligopeptide oligopeptide oligopeptide oligopeptide oligopeptide α Ni 2+ an an Ni 2+ an Ni 2+ Ni 2+ an an an an an an an an a ferric a ferric a ferric a ferric a ferric a ferric iron(III)- iron(III) dicitrate iron(III) dicitrate iron(III) dicitrate iron(III) dicitrate iron(III) dicitrate iron(III)- 3,5- 3,5- a C4- a C4- -L- a branched- a branched- a dicarboxylate 2-amino-2- 2-amino-2- a dicarboxylate a dicarboxylate a dicarboxylate a dicarboxylate a dicarboxylate L-alanyl-γ-D- L-alanyl-γ-D- L-alanyl-γ-D- L-alanyl-γ-D- L-alanyl-γ-D- L-alanyl-γ-D- L-alanyl-γ-D- L-alanyl-γ-D- L-alanyl-γ-D- L-alanyl-γ-D- an an Ni 2+ an an an an an Ni 2+ an Ni 2+ an an malonate malonate malonate α-L- a carbohydrate phosphonate a polar a polar D-gluconate D-gluconate a dipeptide a dipeptide an oligopeptide oligopeptide oligopeptide an oligopeptide oligopeptide an oligopeptide an oligopeptide oligopeptide oligopeptide oligopeptide oligopeptide oligopeptide oligopeptide oligopeptide oligopeptide hydroxamate hydroxamate hydroxamate hydroxamate hydroxamate hydroxamate enterobactin iron(III)-enterobactin complex iron(III)-enterobactin complex iron(III)-enterobactin complex iron(III)-enterobactin complex iron(III)-enterobactin complex enterobactin dimethoxytoluene dimethoxytoluene dicarboxylate dicarboxylate arabinopyranose chain chain a capsular a capsular dCTP deoxy-D- deoxy-D- dCTP dCTP dCTP dCTP dCTP glutamyl-meso- glutamyl-meso- glutamyl-meso- glutamyl-meso- glutamyl-meso- glutamyl-meso- glutamyl-meso- glutamyl-meso- glutamyl-meso- glutamyl-meso- oligopeptide oligopeptide an oligopeptide oligopeptide oligopeptide oligopeptide oligopeptide oligopeptide an oligopeptide oligopeptide an oligopeptide oligopeptide oligopeptide phosphonate arabinopyranose a carbohydrate amino acid amino acid an an an an an an complex complex complex complex complex complex complex complex amino acid amino acid polysaccharide polysaccharide gluconate gluconate diaminopimelate diaminopimelate diaminopimelate diaminopimelate diaminopimelate diaminopimelate diaminopimelate diaminopimelate diaminopimelate diaminopimelate oligopeptide oligopeptide oligopeptide oligopeptide oligopeptide oligopeptide This diagram was automatically generated by SRI International Pathway Tools version 25.0, authors S. Paley and P.D. Karp.