“For the Discovery and Development of the Green Fluorescent Protein, GFP” P I X J
2008 NOBEL LAUREATES The Nobel Prize in Chemistry 2008 “for the discovery and development of the green fluorescent protein, GFP” X O I P G SCAN ICAL LABORATORY ICAL ORNIA, SAN DIE ORNIA, SAN G F J. HENRIKSSON/ CALI F UNIVERSITY O TOM KLEINDINST/MARINE BIOLO TOM Osamu Shimomura Martin Chalfie Roger Y. Tsien 1/3 of the prize 1/3 of the prize 1/3 of the prize Born: 1928 Born: 1947 Born: 1952 Birthplace: Japan Birthplace: United States Birthplace: United States Nationality: Nationality: Nationality: Japanese citizen US citizen US citizen Current position: Current position: Current position: Professor Emeritus, Marine William R. Kenan Jr Professor, University of Biological Laboratory (MBL), Professor of Biological California, San Diego, Woods Hole, Massachusetts, Sciences, Columbia La Jolla, California, USA USA, and Boston University, New York, University Medical School, New York, USA Massachusetts, USA CHEMISTRY 7 Copyright Nobel Web AB 2008. Nobelprize.org, Nobel Prize and the Nobel Prize medal design mark are registered trademarks of the Nobel Foundation. 2008 NOBEL LAUREATES Speed read: Illuminating biology IBRARY L The story begins with Osamu Shimomura’s research OTO OTO H into the phenomenon of bioluminescence, in which chemical reactions within living organisms give off CIENCE P CIENCE light. While studying a glowing jellyfish in the early S / X 1960s he isolated a bioluminescent protein that gave off blue light. But the jellyfish glowed green. Further studies revealed that the protein’s blue light ANTATOMI H was absorbed by a second jellyfish protein, later P called green fluorescent protein (GFP), which in turn re-emitted green light.
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