Harvard Physician Named Head of Surgery Department

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2£Tb 'ON xoe UNIVERSITY \H3nWVS SW IN ST. LOUIS Vol. 22 No. 16 Jan. 15, 1998 Harvard physician named head of surgery department

Wells is leaving Washington Univer- Wells to be director sity to become director of the American of College of Surgeons College of Surgeons (ACS), effective July 1, 1998. With 63,000 members, the ACS is the largest surgical organization Timothy J. Eberlein, M.D., the in the world. Richard E. Wilson Professor of "The Department of Surgery has a Surgery at Harvard Medical long history of great achievements in School and vice chairman for research in patient care discovery and education, the Department of Surgery at Brigham most recently under the direction of Dr. and Women's Hospital, has been named Samuel Wells," said William A. Peck, head of the Department of Surgery and M.D., executive vice chancellor for Bixby Professor at the School of Medi- medical affairs and deal of the medical cine, effective Jan. 1, 1998. school. "We are most fortunate, there- Eberlein succeeds Samuel A. Wells fore, that Dr. Tim Eberlein will succeed Jr., M.D., professor of surgery, who had Dr. Wells. Dr. Eberlein is a most out- served as head of surgery since 1981. standing clinical surgeon, researcher and Wells, renowned for research and clinical teacher, and he has the vision to lead the expertise in oncology and endocrinology, department to even greater heights." developed the first genetic test for a Eberlein said: "It is an honor to suc- particular form of thyroid cancer. A ceed Dr. Wells, who has left what can simple surgery can prevent the disease. Continued on page 8 Kasthuri is new Rhodes Scholar; to study neuroscience at Oxford Narayanan "Bobby" Kasthuri, a about how the United States might be School of Medicine student, is different." He perfected his English by one of 32 Americans to receive a watching cartoons. Rhodes Scholarship to Oxford University, "I think my childhood was pretty England this year. He will begin his normal," he added. "I played a lot of studies in the fall. sports, and I hated school like everyone "I'm very excited and definitely hon- else." After attending high school in New ored" said Kasthuri. "But I haven't really Jersey, Kasthuri graduated from Princeton sat down and thought about what it will University in 1996 with a degree in mean and what it will be like to move to molecular biology and public policy. another country for three years." Kasthuri attributes much of his Kasthuri is the 18th Rhodes Scholar academic success to his parents, who from Washington University. Awarded on always placed a lot of emphasis on educa- the basis of academic excellence, integ- tion and doing well. Scientifically, he rity, leadership ability and athletic prow- credits a molecular biologist he worked ess, the scholarships provide two to three with at Princeton and Lichtman. Framed by the Gateway Arch symbolizing the exploration of the American West, years of study and include tuition and a Lichtman, he said has a good sense of Steve Fossett's Solo Spirit balloon awaits its own voyage of exploration New stipend. Kasthuri will pursue a doctorate humor and is very accessible. Kasthuri Year's Eve. in neuroscience. He currently has a Howard Hughes Medi- Equipment failures, weather cal Scholarship and is studying for a master of arts degree in the end Solo Spirit trip in Russia University's M.A./M.D. program. He is work- It was a long ride — 7,300 miles — ond-longest balloon flight in aviation ing with Jeffrey and it was exciting, but Steve history, exceeded only by his own epic Lichtman, M.D., Ph.D., Fossett's quest to fly his balloon 1997 journey of 10,361 miles from professor of neurobiol- around the world ended prematurely in a St. Louis to India. ogy, on visualizing Russian wheat field at 5:27 a.m. (CST) Technical difficulties contributed to changes at the junc- Monday, Jan. 5, near Krasnodar, a com- the Krasnodar landing. A malfunctioning tions between develop- munity close to the Black Sea. in-cabin heater that dropped nightly ing nerve and muscle Fossett, a Washington University capsule temperatures into the teens and a cells in mice. alumnus and trustee and an international faulty mechanism in one of two Solo Lichtman described adventurer, inadvertently put Krasnodar Spirit propane burners made traveling Kasthuri as wonder- on the map while accomplishing yet extremely difficult, jeopardizing a safe fully inquisitive. "He's another ballooning feat: It was the sec- journey. For nearly two days, Fossett had got a very good mind to climb outside his bubble-top capsule and he asks very diffi- to fire the second burner when the sole- cult questions," he said. In this issue ... noid electronic valve failed. At the medical Earlier in the flight, on Jan. 2, he was school, Kasthuri has Allergic diseases 2 forced to unload about 80 gallons of fuel volunteered with the Rhodes Scholar Narayanan "Bobby" Kasthuri examines Scientists have identified a genetic — 10 percent of his 20-day supply — Students Teaching a slide in his lab at the School of Medicine. mutation that appears to make over the Atlantic Ocean to raise the AIDS to Students people more susceptible to allergies balloon above a bad weather system. program, the Perinatal Project and the described him as an outstanding mentor. Then the winds changed, putting him on Pediatric Outreach Program. "He was one of the main reasons I Exploring connections 3 a trajectory to pass over Libya, a country Born in India, he moved to the United thought about pursuing science," he said. Neurobiologist Joshua Sanes, Ph.D., from which he had not yet received States when he was 5. His parents had At Oxford, Kasthuri is looking forward leads his field in probing the ways overflight permission. He changed his emigrated two years earlier, leaving him to becoming a better scientist. He also nerve cells connect in synapses course to avoid Libya, but in so doing with his grandparents until they found hopes to learn from the other scholars. encountered very light winds that slowed jobs and became established. Eventually, "Nothing like this has happened to me Solo Spirit 6-7 his speed to as low as 20 miles per hour. they both earned master's degrees at before, so I'm not sure how to think about It was the malfunctioning heater and Balloonist Steve Fossett captures American universities. it," he said. "It's just amazing." world attention in his attempt to fly burner, both improved versions of the "As a result, I mostly associated mov- Kasthuri plans to finish his medical non-stop around the globe 1997 equipment, that left Fossett and his ing here with getting to be with my par- degree at the School of Medicine after he team mOSt perplexed. Continued on page 8 ents again," Kasthuri said. "I didn't think returns from Oxford. — Diane Duke 2 Washington University Record Medical Update Schreiber named to Elaine and Mitchell Yanow Professorship

Editor's note: At press time, the Record to the University. Yanow was an alumnus William H. Danforth, chairman of national Inc., the nation's leading received word of Mitchell Yanow s death of the University and the medical school. the Board of Trustees, called Yanow "a operator of community-oriented fran- Monday, Jan. 12. An announcement about "We are grateful to the Yanow family man of vision and integrity, to whom chised pharmacies. Yanow also co- funeral arrangements and a memorial for their generous commitment," said we are deeply indebted." founded OB-GYN Inc., one of the area's service will be published in the St. Louis Chancellor Mark S. William A. Peck, M.D., executive earliest obstetrics-gynecology group Post-Dispatch. Wrighton. "En- vice chancellor for medical affairs and practices. dowed chairs are dean of the medical school, said: "This The late Elaine Yanow was well known The late Mitchell Yanow, M.D., a the greatest honor professorship will recognize and honor for her deep commitment to civic affairs. St. Louis area obstetrician-gynecolo that a university in perpetuity two individuals who have During her tenure as a board member and gist and a notable entrepreneur, can bestow on its meant so much to Washington Univer- president of the League of Women Voters established the Elaine and Mitchell Yanow faculty, and the sity. It will have a great impact on the of St. Louis, she researched and advocated Professorship in the School of Medicine's Yanow Professor- Department of Obstetrics and Gynecol- ways to improve government services, Department of Obstetrics and Gynecology. ship will play an ogy, aiding in the attraction and reten- including a metropolitan sewer district, a James R. Schreiber, M.D., head of the important role in tion of outstanding academic leaders." nonpartisan court plan and a mass transit Department of Obstetrics and Gynecol- helping us attract In addition to a long and accom- system. ogy, has been named the first Elaine and James R. Schreiber and retain out- plished medical career, Yanow was well The Yanows were life benefactor Mitchell Yanow Professor. standing faculty, known for his entrepreneurial skills. He members of the William Greenleaf Eliot Over the years, the Yanows gave gener- who are so crucial to the strength and was chairman of the board and Society. Each year, the Yanows gave to ously of their time and financial support reputation of an academic institution." co-founder of Medicine Shoppe Inter- the medical school to support scholarship programs for medical students. In 1993, the University recognized Mitchell Yanow with a Distinguished Alumni Award. Yanow received his medical degree in 1941. From 1958 to 1990, he was a member of the clinical faculty in obstetrics and gynecology at the medical school. Until his death, he was an assistant professor emeritus of clinical obstetrics and gynecology. Schreiber came to the University in 1991 to head the Department of Obstet- rics and Gynecology. Working with the BJC Health System, he plays an integral role in expanding women's and children's health services throughout the St. Louis region. Schreiber's research focuses on the causes of infertility. He and his co-workers at the medical school are the recipients of a five-year, $2.25 million National Institutes of Health grant to determine whether immunotherapy or psychological support can help women with repeated unexplained miscarriages carry babies to term. Student and Employee Health is relocating The School of Medicine Student and Employee Health Service is relocat- Holiday generosity ing to Room 3420 of the East Building, From left: Ruth Hogenkamp, accounting assistant in the Department of Cell Biology and Physiology, and Susan Ander- 4525 Scott Ave., Jan. 16. The phone son, program administrator at the Medical Center's Redevelopment Corp., give Christmas gifts to Katherine Strawder as numbers will remain the same. the Rev. Jimmie L. Ward looks on. As part of the recent Adopt-A-Family program in the Forest Park Southeast neighbor- hood, 20 School of Medicine departments adopted 23 families and provided them with food, clothing, toys and other items. Area ministers identified families in need. Scientists identify strong genetic link to allergies Record Allergic diseases are among the called immunoglobin E (IgE). The IgE Environmental factors also play a role Editor: Betsy Rogers, (314) 935-6603, major causes of illness and dis- molecules then attach themselves to mast in determining whether an individual Campus Box 1070 ability in the United States, affect- cells in tissues and basophils in blood. develops allergies. Previous studies have Associate vice chancellor, executive director, ing as many as 40 million to 50 million When an allergen encounters the IgE, it established that avoiding particular aller- University Communications: Judith Jasper Americans. Researchers have known for attaches to the antibody like a key fitting gens in childhood substantially decreases Executive editor: Susan Killenberg some time that allergies have a genetic into a lock. This signal tells the mast cell the risk. Breast feeding also helps guard Editor, medical news: Diane Duke, link, but information about which genes or basophil to release — and in some cases a child against allergies. 286-0111, Medical School Box 8508 are responsible has been limited. Now, to produce — powerful inflammatory Assistant editors: Martha Everett, 935-5235 Identifying the altered receptor gene David Moessner, 935-5293 School of Medicine scientists have identi- chemicals like histamine, prostaglandins could greatly aid studies of allergic Production: Galen Harrison fied a genetic mutation that appears to and leukotrienes. The production of these reactions. "This finding will help us Record (USPS 600-430; ISSN 1043-0520), make people more susceptible to allergies. chemicals in various parts of the body, identify individuals at high risk of devel- Volume 22, Number 16/Jan. 15, 1998. Pub- "This is one of the strongest associa- such as the respiratory system, initiates an oping allergies and evaluate intervention lished for the faculty, staff and friends of tions so far between any one particular . allergic reaction, such as is seen in asthma. strategies aimed at protecting these Washington University. Produced weekly gene and allergies," said Talal A. Chatila, IgE is key to this process because it triggers individuals from developing allergic during the school year, except school holidays, M.D., an associate professor of pediatrics and monthly during June, July and August by the chain of events that leads to symptoms. disorders," Chatila said. the Office of Public Affairs, Washington and senior author of the study, which Another key protein is interleukin-4, The genetic finding also could help University, Campus Box 1070, One Brookings appeared in the Dec. 11, 1997, issue of which induces immune cells to make IgE. researchers develop better medications to Drive, St. Louis, MO, 63130. Periodicals The New England Journal of Medicine. Chatila and his colleagues studied the treat allergies. Because the identified postage paid at St. Louis, Mo. "We have found that if you have this receptor for interleukin-4. Using techniques target is unique, Chatila said, drugs could Address changes and corrections: mutation, you are 10 times more likely to called single-strand polymorphism analy- be developed that are more specific and Postmaster and non-employees: Send to be allergic." sis and DNA sequencing, they searched for have fewer side effects. Record, Washington University, Campus Box 1070, One Brookings Drive, St. Louis, In the short term, this finding will help variations in the gene for one of the sub- This discovery is an important first MO, 63130. advance studies to identify highly suscep- units of the interleukin-4 receptor. Then step. "We know that the process by which Hilltop Campus employees: Send to Office of tible individuals, Chatila said. The dis- they determined how common the variant some people develop allergies is not Human Resources, Washington University, covery also could lead to more targeted was in patients with severe allergic inflam- random but is genetically determined" Campus Box 1184, One Brookings Drive, medications for allergies. matory disorders and in healthy adults. Chatila said. "This study helps clarify the St. Louis, MO, 63130. The immune system normally defends One variant occurred at high frequency basis for this genetic predisposition." Medical Campus employees: Send to Payroll the body against invading agents, such as in patients with allergic inflammatory In addition to Chatila, other authors of Office, Washington University, Campus Box 8017,660 S. Euclid Ave., St. Louis, MO, 63110. bacteria and viruses. But it sometimes disease and in adults with various allergies this study are lead author Gurjit K. confuses other foreign substances, such as Electronic Record: To view the Record on the but at a low frequency in adults with no Hershey, M.D., Ph.D., now at the Univer- World Wide Web, go to http://wupa.wustl.edu/ dust mites and certain foods, with harmful allergies. This genetic alteration occurred sity of Cincinnati School of Medicine; record7record.html intruders. When some people first come at the tail end of the interleukin-4 receptor, Michal F. Friedrich, now at Loyola Uni- into contact with such allergens, their Chatila and his colleagues discovered. The versity School of Medicine; and Matthew immune systems mobilize to respond. consequence, they showed was that the L. Thomas, Ph.D., and Laura A. Esswein, li\)vMTirigton First, they generate large amounts of an receptor becomes hyper-responsive when M.D., at the medical school. WASHINGTON • UNIVERSITY- IN • ST- LOUIS antibody — a disease-fighting protein — stimulated with interleukin-4. — Diane Duke Jan. 15, 1998 3

Neurobiologist makes key connections

Anyone who has installed a computer will McMahan showed that signals in the synaptic part of molecules called ephrins. understand the problem that occupies the basal lamina tell the tip of a regenerating axon to In 1983, the course of Sanes' career was changed by Josh Sanes. Those who have strung a stop growing and turn into a presynaptic nerve termi- the arrival of John Merlie, Ph.D., at the Department of network will appreciate it even more. nal. Pharmacology. Merlie was studying the development of Take a trillion or so wires and thread To explore the nature of these signals, Sanes the postsynaptic membrane, particularly acetylcholine them where they need to go, avoiding mismatches, moved to the University of California at San Francisco receptors, which are studded under the presynaptic knots and tangles. Make tiny adaptors to hook each in 1978, finishing his postdoctoral studies with neuro- terminal like pins in a pincushion. "We started to work wire in place. chemist Zach W Hall, Ph.D. together closely because we enjoyed each other's com- The nervous system's success depends on making "Josh thinks and writes in an exceptionally clear pany and had similar interests but complementary skills," the right connections. But as it reaches to the corners and well-organized way, so that he always seems to Sanes explained. "I soon got interested in how the syn- of a developing organism, no one is standing with a have a sure sense of what the important questions are, apse is put together, while John got interested in recogni- wiring plan in hand. So how do its lengthening wires even when others do not," said Hall, who now is direction molecules." know where to go? And how do they know when tor of the National Institute of Neurological Disorders Sanes and Merlie identified a new signaling molecule to stop and form connec- in the basal lamina that tions? now is named laminin-82. The second question After cloning the gene, interests Joshua R. Sanes, they inactivated it in mice, Ph.D., professor of neuro- preventing the animals biology. When the tip of a from making laminin-132 nerve fiber reaches another protein. In 1995, Sanes neuron or muscle fiber, it and Merlie reported in the changes from a graceful, journal Nature that the mobile cone to a static, laminin-62-free mice knobby presynaptic termi- formed neuromuscular nal — a nerve ending that synapses that were struc- makes contact with a target turally and functionally cell. The point of contact abnormal. "So we learned then becomes a complex that laminin-B2 is one of structure called a synapse. the signals that muscles Synapses transmit informa- use to direct motor axons," tion from nerve cells to Sanes said. "But we also their partners like modems learned that there must be passing data to computers. additional signals." In the brain, they play key Sanes helped Merlie roles in memory and show that muscle fibers learning. selectively synthesize Little was known about acetylcholine receptors in synapse formation when regions of postsynaptic Sanes began to tackle the membrane opposite nerve problem in 1977. Since terminals. To explore the then, he has systematically roles of other muscle identified the molecules in proteins, the collaborators one type of synapse, deter- generated mice that lacked mining where they are and Joshua R. Sanes, Ph.D., (left) and postdoctoral fellow Guoping Feng, Ph.D., examine DNA manipulated to other components — what they do. produce a mutant mouse. proteins called rapsyn, "What interests me is utrophin and dystrobrevin. specificity — how a nerve cell in the brain or limb and Stroke in Bethesda, Md. "This quality, coupled "Josh now is at the very forefront of developmental unerringly grows toward the right part of the brain or with his high scientific standards and his broad knowl- neurobiology," Hall said. "His recent experiments using body, the right target cell and even the right part of the edge, have made him a wonderful resource to his gene disruption experiments in mice to define right target cell," Sanes said. "That's probably the most colleagues, as well as a major influence in our field." synaptogenesis, undertaken with John Merlie, are already amazing feature of our nervous system — and a pre- Sanes joined the Washington University School of classics in our field." requisite for the brain's ability to think and feel." Medicine in 1980 as an assistant professor of physiol- This fruitful collaboration ended tragically on May Sanes would have become a psychologist if he had ogy and biophysics. Dale Purves, M.D., formerly at 27, 1995, when the 49-year-old Merlie died of cardiac followed his earliest interest. Growing up in Buffalo, the medical school and now chair of neurobiology at arrest. Since then, Sanes has worked hard to advance the N.Y., in the 1950s, he devoured books on psychoanaly- Duke University Medical Center, was instrumental in research program. "Josh has continued to push ahead, in sis and mental illness. Then in high school, he took a recruiting Sanes. "Josh had been a stand-out graduate part by making and maintaining strategic alliances with summer job with Robert Guthrie, M.D., Ph.D., at student and had gone on to do imaginative and impor- researchers in industry and academia who could supply Buffalo's Children's Hospital. Guthrie had been a tant postdoctoral work," Purves said. "His ability to the kinds of reagents and molecular brute force neces- " microbiologist until he fathered a child with severe sary for this kind of work," said Jeff Lichtman, M.D., mental retardation. He then began using bacterial Ph.D., professor of neurobiology. mutants to detect biochemical aberrations associated The work led to a medical breakthrough when Sanes with mental disorders. One of his tests — for phenyl- and R. Mark Grady, M.D., an instructor in pediatric ketonuria — still is routinely given to newborns. "Josh thinks and writes in cardiology who previously worked in Merlie's lab, bred Working in Guthrie's lab introduced Sanes to bio- mice lacking both utrophin and a very large protein chemistry. Putting this interest to work during his an exceptionally clear and called dystrophin, creating the first realistic animal senior year at Yale, he wrote an' undergraduate thesis model of Duchenne muscular dystrophy. on the neurochemistry of schizophrenia. After graduat- well-organized way, so that ing Phi Beta Kappa with a dual major in biochemistry Junctions between nerve cells and psychology, he became a graduate student at Three to four years ago, Sanes decided to apply the find- Harvard. But after the schizophrenia project "failed to he always seems to have a ings from the neuromuscular junction to synapses pan out, he switched to developmental neurobiology, between neurons, hoping eventually to explore key func- studying nerve development in the antennae that give sure sense of what the tions of the brain. He therefore embarked on studies of moths their exquisite sense of smell. neuron-to-neuron synapses in the midbrain and auto- Not convinced he wanted to stay in academe after important questions are, nomic nervous system. "There is reason to believe that he finished his Ph.D. in 1976, Sanes took a job in these synapses will resemble the neuromuscular junc- Washington, D.C. He spent a year at the now-defunct even when others do not." tion," Sanes said. "The molecules may be different, but Congressional Office of Technology Assessment, the principles are likely to be the same." writing reports and dating co-worker Susan Corcoran, — Zach W. Hall Away from the lab, Sanes' priority is his family. He who subsequently became his wife. But the allure of and his wife have an 11-year-old son, Jesse, and a 9-year- Washington faded, and he returned to Harvard to work old daughter, Milla. He spends the rest of his time read- with anatomist Jack McMahan, Ph.D. ing contemporary American fiction or performing administrative duties. He heads the neuroscience graduate Studying the neuromuscular junction tackle a range of complex issues so successfully program for the medical school and sits on the editorial McMahan was studying the neuromuscular junction — bespoke enormous scientific creativity and energy. boards of nine journals, including Cell, Neuron, the the synapse between nerve and muscle. This readily Josh's accomplishments in the subsequent two decades Journal of Cell Biology and the Journal of Neuroscience. accessible structure is a model for other types of syn- have certainly justified the prediction that he would He is associate editor of Developmental Dynamics and apses, such as those in the brain. The presynaptic nerve turn out to be a major figure in neuroscience." has been a councilor for the Society for Neuroscience. terminal forms one side of the junction, and part of the By the early 1980s, Sanes was purifying basal He also is on the Board of Scientific Counselors at the muscle fiber — the postsynaptic membrane — the laminal proteins and showing that motor axons recog- National Institute for Neurological Disorders and Stroke, other. Inserted between the two is a film of connective nize them in culture systems. He also started to where he reviews neurobiological research performed at tissue called the basal lamina. explore how nerve axons in the hindquarters of an the National Institutes of Health. As a way of studying synapse formation, McMahan animal hone in on posterior muscle fibers rather than Unlike an axon zeroing in on a muscle fiber, Sanes was determining how an injured nerve and muscle those toward the animal's front end. "The idea was to doesn't know exactly where he's heading next. "The reconnect as the damage is repaired. A superb use the neuromuscular junction as a way to study the studies of postsynaptic differentiation have gone so well microscopist, he had noticed nerve endings sitting on cellular and molecular basis of how axons choose one that they have taken up most of our time," he said. "We basal lamina during reconstruction. "We decided that muscle over another," Sanes said. These studies are will continue those but also will try to get back to speci- the basal lamina must have some function," Sanes still in progress, and Sanes is focusing on signaling ficity and recognition. Those topics are closest to my recalled. Building on this observation, he and heart." —Linda Sage Visit Washington University's on-line calendar at http://cf6000.wustl.edu/calendar/events/vl.! Calendar Jan.15-24

8 p.m. Writing Program reading. African and Afro-American studies and Author and writer in residence Benjamin dir. of the Writing Program, will read from Saturday, Jan. 24 Taylor will read from his forthcoming his new poetry collection. Hurst Lounge, 9 a.m. Olin Seminar Series. New Direc- novel. Hurst Lounge, Duncker Hall. Duncker Hall. 935-7130. tions in Management program. "The Art and 935-7130. Science of Conflict Resolution: Negotiating Wednesday, Jan. 21 Workable Agreements." Judi McLean Parks, Friday, Jan. 16 6:30 a.m. Anesthesiology Grand Rounds. asst. prof, of organizational behavior. 9:15 a.m. Pediatric Grand Rounds. "A "Management of Tracheal Extubation Simon Hall. For costs and to register, call New Strategy for Diagnosis and Manage- After Cardiac Surgery." Nikolaos Skubas, 935-5226. ment of Strokes in Children With Sickle instructor of anesthesiology. Wohl Hospital Exhibitions Cell Disease." Michael R. DeBaun, asst. Bldg. Aud., 4960 Children's Place. prof, of pediatrics. Clopton Aud., 4950 362-6978. "Alberto Meda: process, materials, Children's Place. 454-6006. design." Through Feb. 15. Givens Hall. 8 a.m. Obstetrics and Gynecology 935-6200. Noon. Cell biology and physiology Grand Rounds. "Tissue Selective seminar. "Charge Translocation by the Estrogens and Hormone Replacement "Art of the '80s: Modern to Na/K Pump." Robert F. Rakowski, prof, Therapy." John D. Termine, vice president, Postmodern." Opening reception Jan. 23, and chair, physiology and biophysics, osteoporosis, Lilly Research Laboratories, 5-7 p.m.. Through April 5. Gallery of Art, Finch U. of Health Sciences/Chicago Eli Lilly and Co. Clopton Aud., 4950 upper gallery. 935-4523. Medical School. Room 426 McDonnell Children's Place 362-7139. "Powerful Grace Lies in Herbs and Medical Sciences Bldg. 362-6950. 11 a.m. Assembly Series lecture. Music Plants: A Joint Exhibit on Herbal Medi- Chancellor's Fellowship Conference, cine." Sponsored by Missouri Botanical Monday, Jan. 19 "Public Health, Private Morality and the Tuesday, Jan. 20 Garden Library and Bernard Becker Medi- 4 p.m. Martin Luther King Jr. com- African-American Community." Joycelyn cal Library. Through April 1998. Seventh memorative lecture. Alvin Poussaint, 8 p.m. Washington U. Chamber Orches- Elders, former U.S. surgeon general. tra concert. Program: Legrenzi, Handel floor, Bernard Becker Medical Library, 660 clinical prof, of psychiatry, Harvard Graham Chapel. 935-5285. (See story S. Euclid. 362-4235. Medical School, and dir., Media Center and Mozart. Features soloists Mary Wilson, below.) graduate student in voice, soprano, and Selections from the Washington Univer- for Children, Judge Baker Children's Center, Mass. Sponsored by the medical Seth Carlin, prof, of music, fortepiano. sity art collections. Through April 5. Thursday, Jan. 22 Karl Umrath Hall. 935-4841. Gallery of Art, lower galleries. 935-4523. school's Office of Diversity Programs. 4 p.m. Joint Center for East Asian Stud- Graham Chapel. 362-6854. (See story ies lecture. "The Order of Authenticity: below.) Timelessness in National Histories, 1 p.m. Martin Luther King Jr. retro- China." Prasenjit Duara, prof, of history, spective program. "Thirty Years: The U. of Chicago. Room 331 Social Sciences Dream and Washington University — and Business Bldg., UMSL. 935-4448. Past, Present and the Future." Features music, readings and testimonials. Spon- Friday, Jan. 23 sored by the Martin Luther King Jr. Com- 9:15 a.m. Pediatric Grand Rounds. memoration Committee. Graham Chapel. "Making a Diagnosis of Cystic Fibrosis: 935-5970. (See story below.) New Challenges." Thomas Boat, chair, pediatrics, U. of Cincinnati College of Performances Lectures Tuesday, Jan. 20 Medicine, and dir., Children's Hospital Noon. Molecular Microbiology and Research Foundation. Clopton Aud., 4950 Friday, Jan. 23 Thursday, Jan. 15 Microbial Pathogenesis Seminar Series. Children's Place. 454-6006. 8 p.m. Performing Arts Dept. perfor- 4 p.m. Immunology Research Seminar "Apoptosis and Inflammation in Dysen- Noon. Cancer Center seminar. "Transla- mance. "Washington U. Dance Theatre." Series. "Regulation of Apoptosis Induced tery." Arturo Zychlinsky, asst. prof., The tional Research — New Directions and Contemporary and classic dance. (Also Jan. by Death Receptors." JurgTschopp, Skirball Institute, N.Y.U. Medical Center. Mechanisms." Roy Wu, grants program 24, same time, and Jan. 25, 2 p.m.) Cost: Universite de Lausanne, Institut de Cori Aud., 4565 McKinley Ave. 362-3692. dir., Cancer Therapy Evaluation Program, $10; $7 for students, faculty, staff and Biochimie, Lausanne, Switzerland. Eric P. 8 p.m. Writing Program reading. Carl National Cancer Institute. East Pavilion senior citizens. Edison Theatre. 935-6543. Newman Education Center. 747-3563. Phillips, assoc. prof, of English and of Aud., Barnes-Jewish Hospital. 747-0359. (See story on page 5.) Joycelyn Elders leads off Spring Assembly Series Jan. 21 Former U.S. Surgeon General • Jan. 28 — U.S. Supreme Court South Forty and the Washington Univer- Auditorium. Joycelyn Elders will open Washing- Justice Antonin Scalia will deliver a sity Society for the Arts. (Public seating • April 1 — Mary Frances Berry, chair ton University's Spring 1998 lecture titled "On Interpreting the Consti- will be limited.) of the U.S. Civil Rights Commission, will Assembly Series at 11 a.m. Wednesday, tution." (Public seating will be limited.) • March 11 — Bill Kirby, chair of deliver the annual Martin Luther King Jr. Jan. 21, with the Chancellor's Fellowship • Feb. 4 — Albert Raboteau, a reli- Harvard University's Department of Symposium Address. Conference on "Public Health, Private gious scholar from Princeton University, History, will deliver the Thomas D. • April 8 — Jack Horner, curator of Morality and the African-American Com- will lecture on Fulbright Lecture, titled "The Future of paleontology for the Museum of the munity." Her lecture will take place in "The Search for 'Greater China.'" Rockies, will deliver the Phi Beta Kappa/ Graham Chapel. Common Ground: • March 18 — Neil Gaiman, fantasy Sigma Xi Lecture, titled "Dinosaurs and The Assembly Series, now in its 37th Howard writer and creator of the "Sandman" the History of Evolutionary Thought." year, offers free lectures to the Washing- Thurman." comic book series, will give the Omicron • April 9 — Author Kurt Vonnegut will ton University community and the gen- •Feb. 11 — Delta Kappa Honors Lecture, titled deliver the Chimes and Neureuther eral public. These lectures are planned Jose Ramos- "Myths About Myths, Stories About Library Lecture at 4 p.m. (limited and supported by Student Union, aca- Horta, the recipi- Stories: Sandman and After." seating). demic departments and other groups, as ent of the 1996 • March 25 — Nell Painter, Princeton • April 15 — Former U.S. Sen. Paul well as the Assembly Series Committee. Nobel Peace Prize, University's Edwards Professor of Simon will deliver the annual Benjamin Unless otherwise noted, the lectures will deliver the American History, will deliver the E. Youngdahl Lecture in Social Policy. begin at 11 a.m. in Graham Chapel. Cultural Celebra- annual Women's Week keynote address. • April 22 — Author Naomi Wolf will Joycelyn Elders Elders became U.S. surgeon general in tion Lecture, titled • March 25 — Erich Gruen, Ph.D., close the spring series by delivering the 1993 after being nominated by President "Human Rights: Democracy and the Rule Washington University's John and Women's Society Adele Starbird Lecture, Bill Clinton and was the first African- of Law in the Asia Pacific Region." Penelope Biggs Resident in the Classics, titled "Fire with Fire: The New Female American to hold that post. In December • Feb. 18 — Former U.S. Sen. William will speak on "Pagans and Jews: The Power and How It Will Change the 21st 1994, she resigned from the position in Gray, the Council of Students of Arts and Roots of Anti-Semitism" at 4 p.m. The Century." order to continue her career in medicine. Sciences Symposium's keynote speaker, lecture will take place in Steinberg For more information, call 935-5285. Currently, Elders is serving as a pedi- will deliver a lecture titled "The Role of atric endocrinologist at the University of Historically Black Colleges and Universi- Arkansas Medical Center in Little Rock, ties at the Dawn of the Century." Gray Martin Luther King Jr. program planned where she has been a professor since currently serves as president of the 1978. Her studies have focused on United Negro College Fund. Martin Luther King Jr.'s dream of 7 p.m. program "Thirty Years: The Dream growth in children and the treatment of • Feb. 19 —The Eliot Trio, three harmony and racial equality will and Washington University — Past, hormone-related illnesses, and she has musicians from the St. Louis Symphony be revisited Monday, Jan. 19, in two free, Present and the Future." The program, published articles in a variety of medical Orchestra, will present "A Musical Con- public events commemorating the sponsored by the Martin Luther King Jr. research publications. versation" at 7 p.m. in Steinberg Audito- birthdate of the slain civil rights leader. Commemoration Committee, also will At age 18, Elders graduated from rium. The performance is part of the The commemoration begins with a take place in Graham Chapel. Philander-Smith College. She then St. Louis Symphony Orchestra's Commu- 4 p.m. lecture by Alvin Poussaint, M.D., The retrospective program will include entered the U.S. Army as a first lieutenant nity Partnership Program. in Graham Chapel. The lecture is spon- remembrances from a 1968 alumnus, and received training as a physical thera- • Feb. 24 — Laurence Soderblom, sored by the School of Medicine's testimonials from members of the Class pist. Elders graduated from the University senior research geophysicist for the U.S. Office of Diversity Programs. of 1998 and the thoughts of James of Arkansas Medical School in 1960 and Geological Survey and one of the key Poussaint is a clinical professor of McLeod, dean of the College of Arts and completed a pediatric residency and scientists in the recent Mars Pathfinder psychiatry at Harvard Medical School Sciences and vice chancellor for students. endocrinology fellowship there. expedition, will deliver the William C. and serves as director of the Media Also included will be a greeting from Elders' appearance will kick off an Ferguson Memorial Lecture, titled "Back Center for Children at the Judge Baker Chancellor Mark S. Wrighton, gospel Assembly Series spring schedule that to Mars." Children's Center in Massachusetts. He music performances and readings from features 17 speakers from the fields of • Feb. 25 — Modern dancer Twyla is an expert on race relations in America King's speeches. science, religion, politics, the arts and Tharp will present a lecture/demonstra- and served as script consultant to the For information on the 4 p.m. lecture, academia. Included on the spring slate tion in Edison Theatre. The event is television program "The Cosby Show." call 362-6854. For questions about the 7 are: co-sponsored by the Congress of the The celebration continues with the p.m. celebration, call 935-5970. + Washington University Record / Jan. 15, 1998 5 Architecture school hosts Midwest city design institute Elizabeth Plater-Zyberk, an award- winning architect known for her work at the forefront of urban and community design, will deliver the keynote address Thursday, Jan. 22, for the Mayors' Institute on City Design: Midwest, hosted by the School of Architecture's Research and Design Center. Plater-Zyberk, dean of the University of Miami School of Architecture in Florida, will speak at 7 p.m. in Steinberg Audito- rium. Her talk, titled "Design for the Metropolis," is free and open to the public. Plater-Zyberk, who received a bachelor's degree in architecture and urban design from Princeton University and a master's degree in architecture from Yale University's School of Architecture, has an architectural practice in Miami with Andres Duany. Their firm has designed nearly 200 urban and architectural projects for public agencies and private clients, including housing, office, commercial, civic and religious buildings. She and Duany have been leaders in the national movement known as the Congress of the New Urbanism, which focuses on reforming the physical environment. She From left: Students Lora Farwell, Patricia Skarbinski, Meghan Sullivan, Lindsay Mortimer and John Jimenez perform David also was instrumental in the creation of a Marchant's "I'm Sure We Can Find a Use for You ..." in the "Washington University Dance Theatre" Jan. 23-25. zoning ordinance for Miami's Dade County that offers a "prescription for compact, mixed-use and pedestrian- oriented urban growth as an antidote to urban sprawl." Classic, contemporary dance at Edison The keynote address will kick off the three-day institute, which provides a Contemporary and classic dance the University with high levels of prior graphed by Christine O'Neal, artist in closed forum for invited mayors to discuss are the focus when "Washington training," Cowell added. "Consequently, residence and director of the ballet city design strategies,with urban designers University Dance Theatre" comes the technical level they are able to perform program; and other city development professionals. to Edison Theatre Jan. 23-25. Presented by at has been on the rise. The Dance Theatre • "Private Storms" by choreographer This is the fifth year the school's Research the Performing Arts Department in Arts provides them a terrific opportunity to Paul D. Mosley, founder of Paul D. and Design Center has hosted the confer- and Sciences, this annual showcase for work with professional choreographers and Mosley Dance Inc. in New York and a ence, which is sponsored by the National outstanding young talent features more to perform professional-level works." 1984 University alumnus; Endowment for the Arts. The forum than 40 top student dancers, selected by One such work will be a reconstruc- • "After Darkness, Songs," the pre- focuses on architecture, landscape archi- audition, performing a variety of profes- tion of Doris Humphrey's 1928 modernist miere of a new piece choreographed by tecture, historic preservation, growth sional-quality works by both faculty and classic "Water Study," directed by visiting Cowell; planning and management and urban guest choreographers. Performances are at artist Carl Wolz, director of the World • "Untitled," a work for a single design and development. Mayors attending . 8 p.m. Jan. 23 and 24 and at 2 p.m. Jan. 25. Dance Alliance and a professor of dance dancer, and "I'm Sure We Can Find a Use this year are from Maywood, 111.; Chester- "Typically the Dance Theatre focuses at the Japan Women's College of Physical for You ..." a collection of wry, light- field, Mo.; Appleton, Wis.; Kentwood, on contemporary dance," said Mary-Jean Education. "Water Study" abstracts move- hearted "theatrical/dance non-sequiturs" Mich.; Terre Haute, Ind.; Alton, 111.; and Cowell, Ph.D., associate professor of ments from the natural world in order to for 16 dancers choreographed by David Clinton, Iowa. dance and coordinator of the dance evoke images of waves in changing W Marchant, a fourth-year artist in resi- "Mayors have great influence on the program. "This year, however, we are weather. The piece represents one of the dence. physical environment of their cities," said expanding our offerings to include a earliest efforts in modern dance to shed Tickets are $10 for the general public Cynthia Weese, FAIA, dean of the School recognized masterwork of traditional reliance on elaborate costumes, stage and $7 for senior citizens and University of Architecture. "This institute is a very ballet and a classic work from the mod- technology and even, in this case, music. faculty, staff and students. They are avail- effective way of opening their eyes to the ern lineage. Other works to be performed include: able at the Edison Theatre Box Office, possibilities and potential for design "In the last few years we've seen • "Pas de Trois," from Tchaikovsky's 935-6543, and all MetroTix outlets, improvement in those communities." increasing numbers of students arriving at "Swan Lake," restaged and rechoreo- 534-1111. For information, call 935-5858. Other Washington University architecture faculty, staff and students involved in the conference are John Hoal, associate professor and director of the institute; Iain UC courses explore history, opera, urban experience Fraser, professor; Adam Glaser, visiting assistant professor; Diane Trees Howard, A Saturday Seminar lecture series invite dialogue between audience and modern era and is taught by Elizabeth institute contract and grant coordinator; and four short courses will be speakers. Allen, lecturer in Romance languages and Mara Minarik, institute coordinator; and offered to the public for the The theme of this semester's series, literatures in Arts and Sciences. It is graduate students Ian Caine, Christopher spring 1998 semester at University "Times, Places, Cities: Varieties of Urban scheduled for 3-4:30 p.m. Thursdays, Gonzales, Mark Vogl and Dhaval College in Arts and Sciences. Experience," will take participants on a Jan. 29-Feb. 26; course fee is $90. Barbhaya. Alumnus Michael Willis, a Sponsored by University College and intellectual journey to Chicago, ancient • "Writing Missouri" — This course principal with Michael Willis & Associ- the Master of Liberal Arts Program, Athens, medieval Paris and Taipei. Wash- explores the ways Missourians wrote about ates of San Francisco, Calif., is among the Saturday Seminars explore a common ington University faculty will present the themselves and the ways others wrote about panel members. theme from different perspectives and four lectures, which will run from 11 a.m. Missourians from the state's formation in -12:30 p.m. on February Saturdays in 1821 to the turn of the 20th century, and Goldfarb Auditorium, McDonnell Hall. will be taught by Paul Abeln, lecturer in They are free and open to the public. University College in Arts and Sciences and Saturday Seminars are as follows: at the Missouri Humanities Council. It will • Feb. 7 — "Building 20th-century be held from 10-11:30 a.m. Mondays, Chicago: Policies, Technology and Archi- Feb. 2-23; course fee is $75. tecture" presented by Eric Mumford, • "St. Louis Since World War II" - Ph.D., assistant professor in the School of The course, taught by Harry Schwartz, Compiled by Mike Wolf, asst. athletic director for media relations, and Kevin Bergquist, Architecture; visiting professor in the School of Archi- asst. director, sports information. For the most up-to-date news about Washington • Feb. 14 — "Mud and Marble in tecture and in the College of Arts and University's athletics program, access the Bears'Web site at www.sports-u.com. Ancient Athens" by Susan Rotroff, Ph.D., Sciences, will review the changing nature professor of classics in Arts and Sciences; of the St. Louis metropolitan region over Klein nets two awards Bears snap skid • Feb. 21 — "Medieval Paris" with the last half century. It will be held from Senior football co-captain Brad Klein Norris J. Lacy, Ph.D., chair and professor 5:15-6:45 p.m. Wednesdays, Feb. 4-25; WU's men's basketball squad halted a of Romance languages and literatures in course fee is $60. had to make room for another two awards five-game losing skid with a 77-66 Arts and Sciences; • "Opera '98: Tales ofYouth Restored on his mantel over the holidays. Klein, victory over Beloit College Jan. 6, then • Feb. 28 — "Taipei, Taiwan: Ethnic and Abandoned Love at Opera Theatre"— now recognized as the most decorated won their University Athletic Associa- Identity in a City Landscape" presented The course explores the four operas to be scholar-athlete in Washington University tion (UAA) home opener Sunday, by Joseph R. Allen, Ph.D., associate presented in the 1998 repertoire of Opera history, was tabbed the lone NCAA Jan. 11, against Johns Hopkins professor of Asian and Near Eastern Theatre of St. Louis: Gounod's "Faust," Division III male athlete (all sports) to University. receive a prestigious Woody Hayes languages and literatures in Arts and Donizetti's "Don Pasquale," Janacek's National Scholar-Athlete award, which is Current Record: 4-8(1-1 UAA) Sciences. "Kat'a Kabanova" and Goehr's "Arianna." given for excellence in academics, athlet- This semester's short courses cover It is taught by Hugh Macdonald, Ph.D., ics, community service and leadership. Women hoopsters sixth four different and dynamic topics. Short the Avis Blewett Professor of Music and courses meet once a week for four or chair of music in Arts and Sciences, and Klein also became Washington U.'s The women hoopsters stayed atop the second-ever football player to receive a five weeks and are taught by University Sue Taylor, lecturer in music. The sched- UAA standings with a 59-41 victory faculty. ule is 2-3:30 p.m. Mondays, April 6-27; $5,000 NCAA postgraduate scholarship. Sunday, Jan. 11, over previously He has now accumulated $33,000 in The short courses are: course fee is $80 ($70 for Friends of unbeaten Johns Hopkins, ranking • "Paris: A Short Biography" —This Music). scholarship money, which includes sixth nationally. $10,000 for Washington U.'s general course highlights Paris as a theme in For more information on University scholarship fund. Current Record: 11-1 (2-0 UAA) works of art and in the popular imagina- College's Saturday Seminars and short tion during key historical periods of the courses, call 935-6788. 4

6 Washington University Record

The media look on as Chancellor Mark S. Wrighton (left) wishes Steve Fossett luck before the launch. Fossett lands in Russia, but excitement circles the globe

From the Washington University community to the lift-off, which occurred well ahead of the launch global news media to millions of Web surfers window earlier predicted. As the flight unfolded, at their home computers, Steve Fossett's Solo some 500 alumni in St. Louis and around the world Spirit adventure stirred interest and captured the continued to follow it via frequent e-mail updates imagination of people worldwide as he sought to be from the office of Laura Ponte, senior director of the first to fly non-stop around the Earth in a balloon. alumni relations. "If the sheer will of millions of supporters could On the Internet, the Solo Spirit Web site received keep him aloft, there would be no doubt of his suc- an astounding 750,000 to 850,000 "hits" every day, cess," wrote one woman to the University's Solo Spirit and University Webmaster Gail Wright sifted Web site. through about 1,500 daily e-mail messages to the And a 9-year-old girl had this message for Fossett: Web site. "My name is Katherine and I am writing to say how Media advisories and alerts to the University brave I think you are. I hope you do not run out of community went out quickly New Year's Eve morn- gas." ing when Fossett confirmed that he would launch An older correspondent wrote: "In years to come I that evening. By midday, the press had begun to will remember New Year's Eve not as a prelude to gather at Busch Stadium. Fossett, with Solo Spirit as 1998 but the beginning of a marvelous adventure his backdrop, spoke with reporters about 4 p.m. shared round the world. I am deeply grateful to Mr. Members of the University community and the Fossett for allowing me to be an observer . . . few of general public had been invited to the stadium at us have the courage to live so completely." 5 p.m. for a planned lift-off between 6 and 9 p.m. There was intense media interest. Reporters and Many came earlier — a fortunate development camera crews crowded around the balloon enclosure because the launch window opened unexpectedly at Busch Stadium Dec. 31 as Fossett, an alumnus and around 5, and Fossett, seizing the opportunity, lifted University trustee, prepared to launch. After lift-off, off at 5:04. Even some camera crews were caught they moved over to the University, where Fossett's off guard and missed the first few moments of the mission control and media center were up and running flight. in Room 300 above the Brookings Hall archway. Solo Spirit rose in gentle winds, however, and The Associated Press, Reuters, United Press Inter- lingered over the stadium for several minutes in the national and Agence France-Presse wire services filed stories throughout the trip, giving international coverage to the venture. The British Broadcasting Corp. followed the flight with avid interest, along with broadcast services from Australia, Belgium, New Zealand, South Africa, Germany and Turkey. The New York Times, National Geographic, Washington Post, Chicago Tribune and Chicago Sun-Times, ABC, NBC, CBS, CNN, PBS, National Public Radio, the St. Louis Post-Dispatch and local television and radio all gave 4 J Solo Spirit comprehensive cover- ? « ♦ yvMj age. About 300 alumni, faculty, staff, ?P > students and other spectators made it to Busch Stadium in time to see

Photos by- Joe Angeles and David Kilper

Fossett checks the burners under his balloon as he prepares to launch. The science payload is at top right. Jan. 15, 1998 7 glow of the sunset, giving the crowd a spectacular view. As Fossett headed southeast across the Mississippi River, the action shifted to mission control at Brookings Hall. From that point until late in the day Monday, Jan. 5, several hours after Fossett landed the balloon in rural southwestern Russia, his team worked around the clock tracking his flight, pursuing overflight permissions and relaying data to him via satellite e-mail and phone. Students and faculty from the Department of Earth and Planetary Sciences in Arts and Sciences helped out. On the other side of a low barrier, the media team from the Office of Public Affairs, led by Associate Vice Chancellor Judith M. Jasper, fielded inquiries and requests for updates from reporters 24 hours a day. Phones, computers and fax machines were rarely idle as the press called in from distant time zones. The staccato pace picked up even more at times. On Friday, Jan. 2, reporters and camera crews crowded into the room for a hastily called briefing to announce that rapidly changing weather patterns were sending Solo Spirit toward Libya, a country that had not yet granted overflight permission. A tense day followed while Fossett's meteorologists found other winds to take him on a more easterly track over the Czech Republic, Hungary and Romania. Then, at midday Saturday, Chief Engineer Tim Cole announced that Fossett had received the necessary Libyan permission. By then he was flying well to the Reporters and cameras crowd the media center (foreground), the ground crew works in mission north of the Mediterranean Sea, missing Libya. control (right) and spectators occupy the gallery above Room 300 Brookings Hall before a Jan. 3 news Though Fossett had hurdled those obstacles, new conference. ones confronted him. At 9:30 a.m. CST Sunday, the team announced that Fossett was having problems worldwide, described his landing and took reporters' e-mail correspondence came from a vast cross- with the capsule heater. Fossett later reported that at questions. section of the public. "There were many school- night temperatures in the capsule would fall to about Alumni kept informed throughout the flight via the children," she said, "probably a fifth of the total. Web site, news reports, an alumni hotline Some of them weren't even old enough to type; and an electronic mail update system that their parents or teachers typed it for them." She Ponte devised. About 500 in this country said there were also many eloquent messages from and as far away as Europe and Asia people who were inspired by the venture. "They requested the e-mail updates. were wonderful to read," she said. Though Fossett John Kourik of St. Louis (B.S., 1948), didn't receive these messages while he was aloft, an engineer and a balloon enthusiast, all of them have been printed out and will be bound attended the launch and found all the and presented to him. preliminaries deeply absorbing. "Just Chancellor Mark S. Wrighton greeted Fossett watching it is. fascinating,to me," he said. during the Monday conference call. "We're grateful Kourik was grateful to be able to stay for your safety," Wrighton told Fossett, "and for in touch throughout the flight. "I really being part of this wonderful and exciting adven- appreciated the e-mail messages," he said, ture." complimenting Ponte and the University On a practical note: Ponte's office has a limited on their efforts on behalf of alumni. Ponte supply of Solo Spirit handwarmers still available, said she had received many return e-mails and she will be happy to send them to anyone who expressing appreciation for the service. has a campus mailbox. To request a pair, e-mail "People really felt that they were part" of [email protected]. the adventure, she said. — Betsy Rogers From left: Graduate students Curt Neibuhr and Susan Mahan, Floyd Crowder, research scientist Edward Guinness, Ph.D., and computer who received a systems coordinator Thomas Stein work at mission control. bachelor's degree from the University 10 degrees Fahrenheit at his feet, about 25 degrees at in 1955 and a law degree in the top of the capsule. 1957, was thrilled to be at the Winds also had fallen off, and Fossett was making launch. "It was participating in slow progress at speeds as low as 20 miles an hour the commencement of a historic across the Black Sea. At midday on Sunday, there event," he said. Crowder was were more weather complications: The winds were deeply impressed by the sight of shifting toward the north and west and threatened to Fossett riding solo in his turn Solo Spirit toward Moscow. About 2:30 a.m. CST balloon's small gondola. "This Monday, his team announced that he was looking for is a man with lots of grit," he a suitable place to land and end the around-the-world remarked. "Floating across the attempt. Atlantic in that gondola takes a Media were on hand immediately and stayed lot of courage — and ability." throughout the morning. Mission Control Director Asked if he hopes Fossett Alan Blount announced at 8:55 a.m. that he had a will try again, Crowder replied: confirmed report of Fossett's safe landing. Then, at 11 "Of course! And I hope he's the a.m., Fossett phoned into mission control and, through first to make it." Mission Control Director Alan Blount (left) and Recovery Director Joe a speaker-phone conference call linked to media Webmaster Wright said her Ritchie await word of Fossett's safe landing and ponder the journey's end.

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tion skills; ability to work well within Requirements: high school diploma; graduate job information; drafting External Reporting Accountant. Office of Human Resources, 4480 Hilltop the office environment and relate eas- four years experience in fund ac- correspondence; arranging for visit- Accounting Systems. Requirements: Clayton Ave., Campus Box 8002, St. ily to people; sensitive to the needs counting, preferably in university en- ing faculty and accreditation visits; bachelor's degree with a major or Louis, MO 63110. Job openings also and mission of Washington Univer- vironment, including experience with and coordinating symposia. concentration in accounting; CPA; may be accessed via the World Wide Campus sity and the role of the Development computer systems, or 60 semester three or more years experience in Web at http://medicine.wustl.edu/ office; able to deal with multiple hours of college including 12 hours Medical Sciences Writer 980189. public accounting firm or equivalent wumshr. priorities. of accounting; ability to read, under- Medical Public Affairs. Requirements: experience in a university accounting Technician (part time) 980602. Information regarding these and stand, interpret and communicate bachelor's degree, preferably in jour- or financial reporting position; work- other positions may be obtained in Requirements: bachelor's degree; Administrative Assistant 980182. agency guidelines; ability to work in a nalism or communications with spe- ing knowledge of Lotus or similar the Office of Human Resources, University College. Requirements: network system; familiarity with data- cialization in medical and/or science spreadsheet applications; excellent previous lab experience; knowledge Room 130, at West Campus. Job some college; excellent verbal, math base software; ability to work inde- writing; graduate degree preferred; written and verbal communication of immunostaining of cells; physical openings may be accessed via the stamina for standing and bending and organizational skills; ability to set pendently with high degree of reliabil- five years professional experience skills; ability to function indepen- World Wide Web at cfOOOO.wustl. priorities, meet deadlines and handle ity; good interpersonal skills. Deci- with the media and public relations; dently and willingness to commit to a over close work. Responsibilities edu/hr/home. If you are seeking em- include general lab duties in neuro- multiple projects. Responsibilities sions made at this position have a demonstrated knowledge of media level of effort required to complete ployment opportunities and are not immunology lab; cell culture; include assisting Director of Summer University-wide impact relative to the requirements and operations; demon- duties under somewhat stressful and currently a member of the Washing- immunostaining cells; reverse- School in planning and implementing grants administered. strated skill in writing and editing; time-constrained circumstances; spe- ton University staff, you may call our summer session and special pro- ability to plan, organize and imple- transcriptase PCR; general lab main- information hotline at 935-9836. Staff cific knowledge of financial account- grams; dealing with faculty and stu- Publications Coordinator 980185. ment a regular program of developing tenance and ordering supplies. members may call 935-5906. ing standards board opinions 116, dents; scheduling classes, preparing Center for the Study of American medical/science features; ability to 117 and 124; familiarity with tax Secretary I (part time) 980806. bulletin and mailings; handling day- Business. Requirements: bachelor's work well with others and to super- Special Events Coordinator 980180. regulations governing preparation of Requirements: high school diploma to-day financial matters; assisting degree in journalism, English or re- vise their work as needed; ability to Olin Library. Requirements: form 990 and the reporting require- or equivalent; some office experience Associate Dean for Administration in lated discipline; experience editing work effectively with faculty, adminis- bachelor's degree, preferably in com- ments of split-interest life income preferred; working knowledge of PCs, calculating refunds; processing regis- technical publications and producing tration and researchers. munications or business; excellent trusts. word-processing programs, data- trations. publications; experience in computer- written and oral communications Application Processor 980190. bases, spreadsheets and e-mail; abil- skills; strong interpersonal'skills; ini- generated design and layout; experi- Construction Accountant 980183. Undergraduate Admissions. Require- ity to interact with patients, volun- tiative, creativity and independent ence with Microsoft Word, Excel, Ac- Accounting Systems. Requirements: ments: high school diploma; word teers and other staff members; some judgment; experience in development, cess, Powerpoint, and Adobe Medical bachelor's degree; two years experi- processing training and experience walking; ability to work afternoons. public relations or related field pre- PageMaker and Photoshop software ence in construction accounting with with PC data entry. Responsibilities Responsibilities include general sec- ferred; higher education experience; programs. job site experience or extensive expo- include facilitating application materi- Campus retarial support for the project admin- ability to plan, organize, implement sure; minimum four years accounting Assistant to the Dean 980186. als pertaining to prospective stu- istrator and the Parkinson Informa- and manage public relations pro- experience; fund accounting knowl- School of Architecture. Require- dents' applications to Washington tion and Referral Center; general cor- grams; familiarity with desktop pub- The following is a partial list of posi- edge preferred; excellent interpersonal ments: certificate or associate's de- University; keying information regard- respondence; maintaining databases; lishing applications. tions available at the School of Medi- skills; service-oriented communicator gree; strong written and verbal skills; ing these applications on-line in a PC cine. Employees interested should photocopying; maintaining inventory of educational and clinical materials; Department Secretary 980181. Major and a team player; PC experience; pro- fluency in Microsoft Word and Excel database; handling telephone calls contact the medical school's Depart- filing; answering phones and taking Gifts. Requirements: associate's de- ficiency in word processing, spread- for report preparation; organizational from prospective students, their par- ment of Human Resources at 362- messages; assisting with preparation gree or equivalent experience; spe- sheet and database management soft- skills. Responsibilities include assist- ents and high school contacts: vari- 7196 to request applications. External of meetings and symposiums; picking cialized secretarial and business . ware applications. ing the dean in preparing written re- ous mail merge and word processing candidates may call 362-7195 for in- up and delivering items within the training; three years general office ports regarding accreditation; faculty duties. formation regarding applicant proce- Government Grants Specialist Medical Center. experience; detail oriented; accuracy meetings, strategic planning and dures or may submit resumes to the 980184. Accounting Systems. in typing and excellent communica-

Eberlein appointed head of surgery- fwmpagei University bond rating raised arguably be characterized as the best depart- clinical expertise in the management of Standard & Poor's has raised the including a strong and growing balance ment of surgery in the country. It will be my breast cancer, gastrointestinal malignan- rating on Washington University sheet, continued strong operating per- privilege to work with Dean Peck and the cies and soft-tissue sarcoma. His current revenue bonds from AA to AA+, effec- formance, a high level of revenue diver- leadership of Barnes-Jewish Hospital and research projects focus on T cell immu- tive Dec. 11, 1997, according to Amy sity, a conservative debt posture and an the BJC network to build on Sam's tradition notherapy, interactions of tumors and Kweskin, University treasurer. The improving admissions profile. of clinical and academic excellence." lymphocytes and identification of tumor rating upgrade affects outstanding debt "We are pleased that Standard & Eberlein received his bachelor's antigens. He has conducted many clini- of approximately $184 million. Poor's recognizes the university's strong degree in biology from the University of cal trials of immunotherapeutic agents Standard & Poor's attributed the financial position," Kweskin said. "The Pittsburgh in 1973 and his medical degree and has supervised treatment protocols rating upgrade on revenue bonds issued rating upgrade should have a positive from the University of Pittsburgh School for various forms of cancer. by the Missouri Health and Educational effect oh the university's cost of . of Medicine in 1977. The American Cancer Society Facilities Authority to several factors, borrowing." Following an internship and residency recently honored Eberlein with a Career at the Peter Bent Brigham Hospital Development Award and a Faculty (Harvard Medical School), Eberlein did Research Award. He is an active member fellowships in surgical oncology and of many professional societies, a fellow Solo Spirit trip ends in Russia -frompagei tumor immunology at the National Insti- of the Royal College of Physicians and "This is a more serious problem this team, assisted by earth and planetary tutes of Health, Bethesda, Md., and in Surgeons in Glasgow, Scotland, and a year than my previous attempts because sciences graduate student Curt Niebur general surgery at the Lahey Clinic, former consultant to the Ministry of now we really had good equipment," and physics graduate student Susan Burlington, Mass. He finished his train- Health in Moscow. He serves on the Fossett said at a phone conference with Mahan, worked diligently at mission ing as chief resident in surgery at the executive editorial board of Annals of reporters Jan. 5. "My team had developed control throughout the trip. Brigham and Women's Hospital, Boston. Surgical Oncology and is on the editorial the equipment. I would sit there in the The science payload, consisting of Widely published, Eberlein is a surgi- boards of six other journals. capsule and see the state of development sensors that measured the position of cal oncologist who is renowned for his — Chris Woolston of our equipment and marvel. Yet it still the balloon and several atmospheric wasn't sufficient. So I have to ask the parameters, was supposed to relay data to question whether we can tweak it some a satellite, which then would bounce it to more and have a better chance or whether JPL and back to the University, where it this becomes a contest between those would be posted on the Web site on a Campus Watch flying in pressurized capsules." near-hourly basis. However, the team got Fossett flew in an unpressurized cap- only 25 percent of the expected down- sule and was equipped with an oxygen links from the satellite. Of those, few The following incidents were reported to the University Police Department from Dec. 8-Jan. 11. Readers with system that served him well throughout were complete data sets. Guinness specu- information that could assist the investigation of these incidents are urged to call 935-5555. This release is provided as a public service to promote safety awareness on campus. Campus Watch now is available on the University Police the flight. But an unpressurized capsule lates that the antenna on the payload was Web site at http://rescomp.wustl.edu/-wupd. doesn't allow a balloonist to fly high functioning poorly because of extremely enough to avoid bad weather such as the cold temperatures, since data seemed to At the request of University City Dec. 8 storms he encountered over England and be returned better when temperatures police, the Record is running the 10:30 a.m. —A staff member reported that Germany. For much of the flight, he was were warmer. following to assist in gathering infor- a cellular telephone that was inadvertently traveling at altitudes of 22,000 or 23,000 Guinness also speculated that the mation: On Dec. 5, 1997, University left on a table at Whittemore House was feet. aluminized mylar covering the balloon's City police arrested Antione Jones of stolen between 9:30 and 10 p.m. Dec. 6. While Fossett did not accomplish his envelope might have interfered with Ferguson for burglary. He is being held Value: $250 goal, he provided worldwide excitement in data transmissions. in St. Louis County Jail. Dec. 11 his third quest to circumnavigate the world Despite these glitches, Guinness and Jones is a potential suspect in sev- in a balloon. He also is the only balloonist the team were pleased with the informa- eral other burglaries in University City 10:52 a.m. —A staff member reported that a painting that had been donated to the attempting the feat to carry a science tion they got. and St. Louis. Washington University University was stolen from the fifth floor of package from the National Aeronautics "What's important is that when we got students were the main targets of these Olin Library. Value: $10,000 and Space Administration (NASA)/ Jet good clear data from the sensors, it crimes, which took place between June Propulsion Laboratory (JPL). The payload matched what we expected of atmospheric 17 and Dec. 5. He also is a potential Dec. 18 was designed to take measurements of the conditions of the Earth, given the weather suspect in the thefts of 10 laptop com- 9:15 a.m. — A student reported that on Earth's atmosphere so that NASA/JPL and the time of year. That can be applied puters on campus. That series of thefts Dec. 17 at 6 p.m. an e-mail file that was could know better how a robotic balloon to future aerobots for other planets." led University Police to issue a Crime inadvertently left logged on in the basement called an aerobot might function in the Niebur had high praise for the experi- Alert on Nov. 14. of Cupples I Hall had been vandalized and several files were removed. atmospheres of Mars or Venus. ence. "I'd rate it a 10," he said. "It was Often the perpetrator wore a restau- Like Fossett's overall mission, the just a lot of fun, working with the mis- rant/delicatessen work uniform and, if Dec. 30 science payload achieved mixed results, sion control team, keeping the communi- approached, said he was looking for a 9:53 a.m. —A staff member reported that according to Edward Guinness, Ph.D., cations between Ed and Tom and the man named Mark. In some instances, between 3 p.m. Dec. 29 and 9:50 a.m. senior research scientist in the Depart- mission control team members open." the perpetrator said his car had broken Dec. 30 the passenger side of a car parked ment of Earth and Planetary Sciences in Through it all, the science team worked down and asked to borrow money. in the lot east of North Brookings Hall was Arts and Sciences. Guinness, Susan feverishly, bustling between charts, maps, Jones has a dark complexion, pock- scratched. « Slavney, systems programmer analyst, computer stations — and TV cameras. marked face and a gold front tooth. University Police also responded to four and Thomas Stein, computer systems "It was a wonderful experience," Anyone with any information additional reports of vandalism, 16 addi- coordinator, collaborated with Raymond Mahan said, "and very strange with all of regarding these crimes is asked to call tional reports of theft, one report of tres- E. Arvidson, Ph.D., professor and chair of the media there. Scientists are used to University Police Detective Steve passing, four reports of harassment, one earth and planetary sciences, who worked working in isolation. We're not used to Hazel at 935-5536 or University City report of burglary, one attempted burglary, one false fire alarm and one peace distur- with NASA/JPL to obtain the science being observed. With all of the media Police Detective Paul Glickert at bance and made one arrest. payload. Arvidson was on a field trip with surrounding us, we had to be careful of 863-3208, ext. 391. students and missed the mission. But his what we said." —Tony Fitzpatrick