Anti-MPP6 Monoclonal Antibody, Clone FQS25268(C) (DCABH-6840) This Product Is for Research Use Only and Is Not Intended for Diagnostic Use

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Anti-MPP6 monoclonal antibody, clone FQS25268(C) (DCABH-6840) This product is for research use only and is not intended for diagnostic use. PRODUCT INFORMATION Product Overview Rabbit monoclonal to VAM1 Antigen Description Members of the peripheral membrane-associated guanylate kinase (MAGUK) family function in tumor suppression and receptor clustering by forming multiprotein complexes containing distinct sets of transmembrane, cytoskeletal, and cytoplasmic signaling proteins. All MAGUKs contain a PDZ-SH3-GUK core and are divided into 4 subfamilies, DLG-like (see DLG1; MIM 601014), ZO1-like (see TJP1; MIM 601009), p55-like (see MPP1; MIM 305360), and LIN2-like (see CASK; MIM 300172), based on their size and the presence of additional domains. MPP6 is a member of the p55-like MAGUK subfamily Immunogen Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human VAM1 aa 1-100. The exact sequence is proprietary.Database link: Q9NZW5 Isotype IgG Source/Host Rabbit Species Reactivity Mouse, Rat, Human Clone FQS25268(C) Purity Tissue culture supernatant Conjugate Unconjugated Applications WB, IP Positive Control 293, HepG2, NTERA2/D1 and Human fetal brain lysates. Format Liquid Size 100 μl Buffer Preservative: 0.01% Sodium azide; Constituents: 59% PBS, 40% Glycerol, 0.05% BSA Preservative 0.01% Sodium Azide Storage Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. 45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected] Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved Ship Shipped at 4°C. GENE INFORMATION Gene Name MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6) [ Homo sapiens ] Official Symbol MPP6 Synonyms MPP6; membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6); MAGUK p55 subfamily member 6; p55T; PALS2; VAM 1; MAGUK protein p55T; VELI-associated MAGUK 1; protein associated with Lin7 2; VAM1; VAM-1; Entrez Gene ID 51678 Protein Refseq NP_057531 UniProt ID A0A024RA25 Chromosome Location 7p15 Function protein binding; 45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected] Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved.

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Analysis of Gene Expression Data for Gene Ontology
ANALYSIS OF GENE EXPRESSION DATA FOR GENE ONTOLOGY BASED PROTEIN FUNCTION PREDICTION A Thesis Presented to The Graduate Faculty of The University of Akron In Partial Fulfillment of the Requirements for the Degree Master of Science Robert Daniel Macholan May 2011 ANALYSIS OF GENE EXPRESSION DATA FOR GENE ONTOLOGY BASED PROTEIN FUNCTION PREDICTION Robert Daniel Macholan Thesis Approved: Accepted: _______________________________ _______________________________ Advisor Department Chair Dr. Zhong-Hui Duan Dr. Chien-Chung Chan _______________________________ _______________________________ Committee Member Dean of the College Dr. Chien-Chung Chan Dr. Chand K. Midha _______________________________ _______________________________ Committee Member Dean of the Graduate School Dr. Yingcai Xiao Dr. George R. Newkome _______________________________ Date ii ABSTRACT A tremendous increase in genomic data has encouraged biologists to turn to bioinformatics in order to assist in its interpretation and processing. One of the present challenges that need to be overcome in order to understand this data more completely is the development of a reliable method to accurately predict the function of a protein from its genomic information. This study focuses on developing an effective algorithm for protein function prediction. The algorithm is based on proteins that have similar expression patterns. The similarity of the expression data is determined using a novel measure, the slope matrix. The slope matrix introduces a normalized method for the comparison of expression levels throughout a proteome. The algorithm is tested using real microarray gene expression data. Their functions are characterized using gene ontology annotations. The results of the case study indicate the protein function prediction algorithm developed is comparable to the prediction algorithms that are based on the annotations of homologous proteins.
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Roles and Mechanisms of Kinesin-6 KIF20A in Spindle Organization During Cell Division T ⁎ Wen-Da Wu, Kai-Wei Yu, Ning Zhong, Yu Xiao, Zhen-Yu She
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WO 2019/079361 Al 25 April 2019 (25.04.2019) W 1P O PCT
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