Empirical Redefinition of Delusional Disorder and Its Phenomenology: the DELIREMP Study ⁎ Enrique De Portugala, , Nieves Gonzálezb, Victoria Del Amoc, Josep M
Available online at www.sciencedirect.com Comprehensive Psychiatry 54 (2013) 243–255 www.elsevier.com/locate/comppsych Empirical redefinition of delusional disorder and its phenomenology: the DELIREMP study ⁎ Enrique de Portugala, , Nieves Gonzálezb, Victoria del Amoc, Josep M. Harod, Covadonga M. Díaz-Caneja e, Juan de Dios Luna del Castillof, Jorge A. Cervillag aDepartment of Psychiatry, Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Hospital General Universitario Gregorio Marañón, Madrid, Spain bResearch and Development Unit, Sant-Joan de Déu-SSM, Barcelona, Spain cDepartment of Psychiatry, Hospital General Universitario Gregorio Marañón, Madrid, Spain dParc Sanitari Sant Joan de Déu, Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Sant Boi de Llobregat, Barcelona, Spain eChild and Adolescent Psychiatry Department. Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM), Hospital General Universitario Gregorio Marañón, Madrid, Spain fDepartment of Psychiatry & Institute of Neurosciences, University of Granada, Spain gCentro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Hospital Universitario San Cecilio, Granada, Spain Abstract Aims: Since Kraepelin, the controversy has persisted surrounding the nature of delusional disorder (DD) as a separate nosological entity or its clinical subtypes. Nevertheless, there has been no systematic study of its psychopathological structure based on patient interviews. Our goal was to empirically explore syndromic subentities in DD. Methods: A cross-sectional study was conducted in 86 outpatients with DSM-IV-confirmed DD using SCID-I. Psychopathological factors were identified by factor analysis of PANSS scores. The association between these factors and clinical variables (as per standardized instruments) was analyzed using uni- and multivariate techniques.
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