July 7, 1992 "Still The Second Vol. XLIV No. 14 Best Thing U.S. Department of Health About Payd4y" and Human Services

National Institutes of Health e Recori___ Governor Schaefer Tours NIH William

Donald Schaefer recently became the first Maryland governor co visitNIH NIH in an official capacity. Sparked by an invitation from Healy, the governor's afternoon at included several lab tours; brief meetings with Drs. French Anderson of NHLBI, Cliff Lane of NIAID, and Steven Rosenberg of NCI; a visit co a patient-care unit; and a stop at the Children's Inn. During his tour of the Clinical Center, Schaefer discussed plans for developing a new $13 million biotechnology center in the state and said being at NIH reminded him of one of the two best jobs he has held-hospital administrator during World War 11. "As the world turns and we move farther from a wartime economy," he said, "more efforts coward prolonging life" will become crucial. NIHHe added that the state has not tapped the abundant resources it has, but his visit co underscores the talent available NIH director Dr. Bernadine Healy helps Maryland Gov. William Donald Schaefer don an NIH and accomplishment achieved virtuallyNIH in Maryland's own backyard. centennial-sealed lab coat he was given during his recent visit here. Healy, he continued, "is the first (Photo: Bill Branson) director co open the doors co us. We haven't Alternatives Explored worked very closely.(See But, GOVERNOR, the doctor has Page BJ NIH Panel Reviews 'Unconventional' Medical Practices vision." Healy said it was appropriate that Established in 1976 A Advisory Committee for By Jim Bryant NIH Women Advances Careers NIH special Office for the Study of Uncon­ of the day." He quoted Dr. Bernadine Healy, ventional Medical Practices has been created at director, as having stated recencly that to explore the effectiveness of out-of-che­ "the innovative scientist is a risk-taker, a spec­ mainstream medical practices; it convenedNIH a ulator in the commerce of ideas." This year will mark the 72nd anniversary 2-day meeting and public hearing by an ad Moskowitz noted that the National Cancer of the 19th Amendment to the Constitution, hoc advisory panel June 17-18 at co Institute has studied the use of natural which guarantees women the right co vote---co begin that process. products-such (Seeas taxol-coALTERNATIVES, combat cancer. Page SJ enjoy the rights and share the responsibilities More than 100 proponents of what has HeSchistosomiasis: cited a recent conference Cytokines on biodiversity of citizenship with men. The ratification of become known as alternative medicine cold the this amendment is celebrated(ACFW), every Aug. 26 as panel about their experiences with such treat­ The Key To Infection? "Women's EqualityNIH Day." The NIH advisory ments as acupuncture, herbal medicine, committee for women established in chiropractic,NIH homeopathy, naturopathy, ayur­ Greg Folkers 1976 by the director, has been working,NIH­ veda, and other modes of healing. They urged By since its inception, for the advancement of co study how these practices mightNIH be women in all areas of employment at incorporated into its clinical trials programs. Schiscosomiasis, a worm infection native co "to enjoy the rights and share the respon­ The meeting was sponsored by the more than 70 tropical and subtropical coun­ sibilities of equal employment with men." Office of the Associate Director forNIH Science tries, afflicts 200 million people worldwide The ACFW is a component of the Federal Policy and Legislation under a $2 million con­ and causes more than 800,000 deaths each Women's Program in the NIH Office of Equal gressional mandate in the 1992 budget year. Among parasitic diseases,NIAID's only malaria Opportunity, working directly with the Fed­ co study the effectiveness of unconventional or causes more disability and death. eral Women's Program manager. The alternative medical practices. Dr. Stephen Recently, researchers at Laboratory committee, composed of representatives from Groft of OSPL is acting head of the new of Parasitic Diseases have begun illuminating each NIH ICD, provides a communication office. what may be the worm's ultimate weapon in channel between women and management and Opening the meeting, Dr. Jay Moskowitz, its baccle against human defenses. The parasite advises the women's program manager on who heads OSPL, called the endeavor "a very appears co evade destruction by coaxing spe­ issues relevant co women. Members of the important and exciting initiative ... the first cific immune system cells to produce NIHACFW have devoted hundreds of hours step of a partnership we hope co build through regulatory chemicals, called cycokines, that reviewing and making recommendations on our clinical trials procedure." cripple the host's defenses against foreign systems, policies, and procedures chat Throughout the history of medicine, organisms. impact on the employment of women; identi­ Moskowitz pointed out, "many great discov­ The investigators have zeroed in on one fying specific issues and (Seepractices WOMEN, that arePage 4J eries were made based on theories chat were such weapon(See disabled SCHISTOSOM/ASIS, in schiscosomiasis: Page nitric BJ barriers co equal employment for women and ridiculed early in their use because they were oxide, a toxic molecule normally secreted by viewed as radical for the conventional chinking page 2 The Record July 7, 1992

'Knowledge Is Power' Symposia NHLBI, WHO Develop Global Asthma Plan Two objectives of the Black Employment Following the release in March of an inter­ treated as a chronic ailment requiring ongoing Program and the Black employees advisory national consensus statement on the diagnosis preventive treatment, rather than as an committee (BEAC) are to increase cultural sen­ and management of asthma, NHLBI, which episodic illness managed with symptom relief. sitivity and awareness among all NIH convened the team of asthma specialists that The international report recommends a six­ employees and to sponsor career enhancement produced the report, has been working with part asthma management plan that should activities to assist employees in the workplace. the World Health Organization to develop a enable people with asthma to control their To accomplish these objectives, the BEAC, strategy for global distribution. symptoms and lead normal lives. The plan under the auspices of the Office of Equal According co NHLBI director Dr. Claude calls for patient education, assessment and Opportunity, will conduct a series of symposia Lenfant, "The international consensus state­ monitoring of asthma symptoms with objec­ entitled, "Knowledge Is Power." ment synthesizes the different approaches to tive measures of lung function, environmental A symposium on the Merit Promotion asthma management adopted by the countries control and avoidance measures co control Program-what it is and how it works-will represented on the panel into a general asthma triggers, use of written medication be held Tuesday, July 14, in Wilson Hall, approach to diagnosing and managing the dis­ plans for chronic asthma management, Bldg. 1 from 11:30 a.m. to 1 p.m. Speakers ease. It should have a major impact on the development of action plans for managing for this event will be Gloria Anderson, person­ way asthma is viewed and treated in Europe acute asthma episodes, and provision of regu­ nel management specialist, OD; Donna and other parts of the industrialized world. lar followup care. Brooks, personnel officer, NIDCD; Juanita "WHO's endorsement and involvement in The international report, which was released Frazier, personnel management specialist, distributing the report will ensure that the through major symposia at the American NCRR; and Fred Walker, chief, Staffing Man­ recommendations are disseminated to public Academy of Allergy and Immunology, the agement Branch, OD. A question-and-answer health officials and leading medical authorities European Academy of Allergy and Immunol­ period will follow the presentations. All on a worldwide basis," he adds. Like the ogy, and the American Thoracic Society this employees are invited to attend. Guidelines for the Diagnosis and Management of spring, is now being translated into Italian, Sign language interpretation will be Asthma released by NHLBI's National Asthma French, German, Spanish, Danish, Japanese provided. For additional information and rea­ Education Program in February 1991, the and Polish. D sonable accommodation, contact the OEO, International Consensus Report on the Diagnosis 496-6301. and Management of Asthma advances a new phi­ Employees are encouraged co forward sug­ losophy of asthma pathogenesis and gestions for topics and speakers to Tyrone management. Emphasizing that inflammation Bellinger, BEAC chairperson, Westwood is the predominant feature in the development Bldg., Rm. 9A04, 496-6301. □ of asthma, the report urges that asthma be The NilIReconl Published biweekly at Bethesda, Md., by the Editorial Operations Branch, Division of Public Information, for the information of employees of the National Institutes of Health, Department of Healch and Human Services, and circulated to nonemployees by subscription only through the Government Printing Office. The content is reprintable without permission. Pictures may be available on request. Use of funds for printing this periodical has been approved by the director of the Office of Management and Budget through September 30, 1992. NIH Record Office Correspondents: Bldg. 31, Room 2B-03 CC, Ellyn Pollack Phone 496-2125 DCRT, Anne P. Enright FAX 402-1485 DRG, N. Sue Meadows FIC, Jim Bryant Editor NCI, Patricia A. Newman Richard McManus NCHGR, Leslie Fink NCNR, June Wyman Assistant Editor NCRR, Polly Onderak Anne Barber NEI, Linda Huss NHLBI, Louise Williams Staff Writer NIA, Carolyn Shanoff Carla Garnett NIAID, James Hadley NIAMS, Amy Iadarola Editorial Assistant NICHD, Carol Florance Marilyn Berman NIDCD, Gail Blatt NIDDK, Eileen Corrigan Serving food at the 10th annual Camp Fantastic Barbecue on June 16 were (from l) Dr. Richard Adamson, The NIH Rec,rdreserves rhe right NIDR, Mary Daum director of NCI's Division of Cancer Etiology; Dr. Philip Pizzo, chief of NCI's Pediatric Branch; Dr. to make corrections, changes, or NIEHS, Hugh J· Lee Duane Alexander, NICHD director; Dr. Ada Sue Hinshaw, NCNR director; and Dr. Gene Cohen, act­ deletions in submitted copy in NIGMS, Wanda Warddell ing NIA director. The barbecue, which benefits a summer camp for children with cancer, drew more than conformity with the policies of the NINDS, Carol Rowan paper and HHS. NLM, Roger L. Gilkeson 1,000 NIH'ers on a sunny afternoon and garnered more than $4,500 for the camp. page 3 The Record July 7, 1992

Donor Day Draws Crowd NIGMS Lauds 20 Years Of MARC, MBRS Programs The Clinical Center's department of transfu­ On July 30, NIGMS will celebrate the 20th sion medicine held its annual awards ceremony anniversary of its Minority Access to Research MARC&MBRS and reception recently in Masur Auditorium. Careers (MARC) and Minority Biomedical Donor Appreciation Day is set aside each year Research Support (MBRS) Programs. These 1972-1992 to thank all 11,660 current blood donors for programs support research and research train­ their contributions to research and patient ing designed to increase the number of care. minority biomedical scientists. The ceremony was kicked off with a Cosponsored by Howard University, the humorous musical skit called "Sharp Needle event will begin at 8:45 a.m. with a scientific and the Fabulous Blood Babes," presented by poster session by MARC and MBRS students the DTM Players. The skit featured their hit who are doing summer research at NIH and song, "Stop in the Name of Blood." elsewhere in the Washington, D.C. area. At On a more serious note, the center was hon­ 10:30, there will be a symposium featuring ored to have Kathleen Kennedy Townsend, research presentations by five outstanding director of the Maryland Student Service MARC and MBRS graduates. These activities Alliance, and Dr. Philip Pizzo, chief of NCI's will take place at the Lipsett Amphitheater, Pediatric Branch, as keynote speakers. Bldg. 10. The graduates who will give these presenta­ TWE NTIETH tions are: Dr. Matthew Edwards, an associate ANNIVERSARY professor of physics and MBRS program direc­ tor at Fayetteville State University in North Carolina; Dr. Mary Sanchez Lanier, an assist- ant professor of microbiology and basic medical science at Washington State Univer­ sity; Dr. Jann Primus, an assistant professor of remarks by Rep. Louis Stokes of Ohio; Dr. biology at Spelman College who is on leave Lafayette Frederick, the MARC program direc­ from that position while she completes a tor at Howard; and Dr. Anthony Andreoli, postdoctoral fellowship in biology at Emory until recently the MBRS program director at University; Dr. Wilfred Denetclaw, Jr., a California State University, Los Angeles. Fol­ postdoctoral fellow in molecular and cellular lowing the luncheon, Howard University will biology at the University of California, hold an afternoon scientific program, which is Berkeley; and Dr. Charles Neal, Jr., a resident scheduled to end at 4 p.m. in pediatrics at the University of California, This event is open to all NIH staff. NIGMS San Francisco, who also plans to pursue a especially encourages attendance by students Kathleen Kennedy Townsend was a keynote speaker at Donor Appreciation Day 1992, held in Masur postdoctoral fellowship in behavioral and who are working at NIH this summer. Auditorium. developmental pediatrics. Edwards and For more information or to register to Sanchez Lanier received support from the attend, call 496-7301 by July 20. Registra­ MBRS program, Primus received support from tion is necessary for the luncheon and Recognized in chis special ceremony were the MARC program, and Denetclaw and Neal requested for other portions of the event. current Hall of Fame donors Dennis Cain, G. received support from both. Transportation from NIH to Howard Univer­ Nelson Sparks, and Dr. Judah Rosner. The The celebration will then move to Howard sity and back will be available to those who three men have exceeded 100 donations and University for a luncheon, followed by brief request it when they preregister. are now pictured among the five past members D in the Blood Donor Hall of Fame exhibit. Afterward, a festive reception was held in the Visitor Information Center. Guests enjoyed NIH Chamber Players Concert Set, July 13 food catered by Chef Theo's Restaurant, The NIH Chamber Players will play a con­ The NIHCP consists of Dr. Suzanne Ep­ t-shirts, raffles and music. Anyone interested cert of music for piano quartet (violin, viola, stein, cellist/immunologist, FDA; Dr. Carl in joining next year's fun can volunteer to give cello and piano) at noon on Monday, July 13 Banner, pianist/molecular neurobiologist, blood at the NIH Blood Donor Center. To in Lipsett Amphitheater, Bldg. 10. The pro­ NIA; Morton Raff, violinist/statistician, for­ schedule an appointment call 496-1048. D gram will include quartets by Faure in c merly with NHLBI; Dr. Edward Max, minor and by Mozart in g minor. This concert violinist/violist/molecular biologist, FDA; Dr. is the 11th in the 1991-1992 series of NIHCP Jere Stern, violist/pathologist, NCI; and Dr. Single Parents Club To Meet concerts sponsored by FAES. Gemma Kuypers, violinist/molecular biologist, The NIH Chamber Players was founded in NIDDK. Occasional guest artists are included. An organizational meeting for the NIH 1988 by a group of scientist-musicians for Plans for the 1992-1993 season include: R&W Single Parents Club is scheduled for whom the performance of chamber music is Schubert-"Trout" Quintet; Mendelssohn­ Monday, July 20, from noon until 1 p.m. in their greatest delight. The group's philosophy sextet; and cello sonatas by Chopin and Bldg. 3 lC, Conf. Rm. 6. All interested single is that first-rate chamber music can be home­ Debussy. D parents are invited to attend. Bring your sug­ made, and that the proper place for such gestions and ideas, in writing, on what you music is everywhere. would like the club to be. For more informa­ tion, contact Betsy Duane, 496-5217. D page 4 The Record July 7, 1992

WOMEN (Continuedfrom Page 1) making recommendations to eliminate the bar­ Career Day draws between 300 and 400 peo­ Summer Student Program; recommended addi­ riers; sponsoring career enhancement activities ple, most of whom are NIH employees. tional security measures for all NIH buildings, that assist women in employment settings; As a result of the Career Day programs, the on and off the reservation; and recommended and identifying recruitment sources for ACFW developed the career enhancement net­ that more women and minorities be included women. work (CEN), a "mentoring program" chat as presenters at NIH's Research Day Members of the ACFW have long recog- matches individuals who wish to change career festivities. nized and expressed their commitment to paths with those who have already made the The ACFW has been very committed to the establish and maintain a more equitable work­ transition. For example, a laboratory techni­ expansion of day care at NIH. In fact, it has place for women at NIH. To chis end, it has cian who is thinking of leaving the bench for been the catalyst for NIH management offi­ sponsored numerous seminars to enhance the an administrative position is put in touch with cials to realize the seriousness of this issue and knowledge and opportunities of employees in a CEN member who has made the transition to move forward on this matter. Such facilities their efforts to achieve advancement at NIH. and can outline the rewards, as well as the at NIH benefit both male and female For example, the committee sponsored an pitfalls, of such a move. The CEN members employees. The lack of allocated space for orientation and panel discussion for women can also respond to questions and offer advice. housing of day care facilities still remains one interested in applying for positions in the This program is now being developed on a of the ACFW's biggest concerns. Several DHHS Women's Management Training Initia­ larger scale under the direction of the OEO to ACFW members are working closely with the tive, a program to give women the encompass all special emphasis groups at NIH day care committee in reviewing the opportunity co train as managers. Information NIH. expansion of day care facilities and services, gleaned from the panel discussion aided In March, the committee commemorates including costs, eldercare, after-school care, women in the preparation of their applica­ Women's History Month with programs cele­ and referral services. tions. The ACFW also contributed to the brating the many accomplishments of women. The committee looks forward to working OEO's 5-year affirmative employment program Women's History Month honors women from with Dr. Bernadine Healy and to continuing plan submitted to DHHS, with subsequent all walks of life who have been leaders in their its efforts in conjunction with her leadership followup. The committee's contribution dem­ fields or have campaigned for or championed of NIH. onstrated the scope and problem of the rights of women. Past speakers for Former members of the ACFW have underrepresentation of women at the higher Women's History Month have included Renee included branch chiefs, program analysts, grades at NIH. Pouissant, local TV anchor; Brig. Gen. Sher­ computer analysts, biologists, secretaries, A manifest imbalance of women at the ian Grace Caderia, who was the highest nurses, statisticians, and health scientist upper levels of employment at NIH still per­ ranking African-American woman in the U.S. administrators. The committee can even boast sists, and the committee, concerned with the Army; and Dr. Beverly Coleman-Miller, for­ of a past member who is now the head of a effects of this issue, has submitted data to mer special assistant for medical affairs, bureau. This wide spectrum of membership OEO illustrating this imbalance and recom­ Commission on Public Health for the District allows for a more universal view of the issues mending solutions. of Columbia. facing women at NIH and helps in setting an The ACFW is also concerned with the The committee also sponsors lunch-time agenda for the ACFW as it strives to make the health of women and has sponsored seminars seminars on topics specific to NIH employees. NIH a more equitable and pleasant place to on health care. Two of these seminars were on In addition, the ACFW has supported the work. 0 estrogen replacement therapy, presented by Dr. Antonia Novello, then deputy director of NICHD. These highly successful seminars, as well as others, attracted crowds of both women and men. "Career Day," another major activity spon­ sored by the ACFW, is held every 18 months. This 3-hour program brings together repre­ sentatives from universities, colleges, and organizations and members of the NIH com­ munity, including role models and staff from personnel and training offices in one general area. Role models are employees who have either advanced in their fields or have changed careers and can discuss opportunities for advancement with others seeking avenues of change. Employees have the opportunity not only to obtain information on alternative careers from NIH role models, but also to talk with uni­ versity representatives in order to develop a Members of the NIH advisory committee for women include ( seated, from l) Patricia Turner, Lucretia Coffer, curriculum integral to achieving their goals Carol Romano, Felicia Brice, Sandy Freund. In middle row are (from l) Natalie Daley, Scarlett Gibb, and objectives. Stafffrom personnel and train­ Marianna Bledsoe, Bonnie Douglas, Dorothy Bank.s, Paulette Campbell, Evelyn Buford, Anita Brook.s. At ing offices are available to discuss an rear are (from l) Barbara Weldon, Sue LaRoche, Joni Smith, Alberta Sandel, Patricia Disque, Dorothy individual's present position or training needs. McKelvin, Virginia Larkin, Shelia Taylor, Dr. Sharon Wahl. page 5 The Record July 7, 1992

Computer Security Speaker Urges 'Safe Computing' Colonel Mustard. In the library. With the candlestick. Crime solved, simple and easy. Right? In the popular board game "Clue," a few logical deductions give the criminal away. But when it comes co computer crime, the culprit may be harder co find. Prevention, of course, is the way to go. Better to practice "safe com­ puting" in the first place, says Dr. Sanford Sherizen, the featured speaker at DCRT's sec­ Jack Campbell ( l) and Marilyn Allen, two members of DCRT's computer security team, with Dr. Sanford ond annual Computer Security Awareness Day, Sherizen of the MIS Training Institute, and DCRT director Dr. David Rodbard ( r ). Sherizen's lecture held recently. "Microcrime and Megabucks," cosponsored by DCRT and CC, was the main event of the second annual Sherizen, a nationally recognized expert on Computer Security Awareness Day. computer security, delivered some sobering warnings to a packed Lipsett Amphitheater audience. In some ways, he says, the "user­ friendly" era may be coming to an end-the under development, may be particularly systematically try passwords from electronic more friendly computers become, the more attractive co computer criminals. dictionaries. It needn't be that hard for the potential they have as tools for crime. So com­ Whether a potential offender is motivated criminals, however; they could likely find puter users must be on guard that their by information, profit, or just plain challenge, passwords on yellow notepaper, in plain view computing practices do not set up oppor­ there are many avenues of entry to a computer at many NIH desks. Additionally, destructive tunities for computer crime or virus attack. system: a modem, a fax, "work-at-home" viruses can enter a system from both hard and More than 1,000 types of computer viruses, equipment, improperly secured software, floppy disks, or computer networks. A virus collectively known as "vandalware," are now "bootlegged" software. According to Sherizen, might reside even in unopened hardware and in existence, with more being developed every people who select simple passwords may also software shipped from the manufacturer. day. And biomedical data such as patient rec­ be vulnerable to system penetration by com­ So what can be done? Try the following ords, databases, and promising technologies puter criminals with programs that suggestions: • know the vulnerable points of a computer system • back up files regularly Security: A DCRT Commitment • use antivirus software to scan all incom­ ing information "I wish there was another word besides system due to inadequate control of the com­ • change passwords frequently 'security,"' says DCRT's Jack Campbell, who puters themselves or poor security habits on • be alert to suspicious computer messages serves as NIH's information system security the part of managers and other employees. or other evidence that could indicate tamper­ officer. "When people think of security, they Another factor is contingency planning. If a ing has occurred. think of the police. They don't realize that natural disaster were to hit the NIH campus, Imagine being the famous Colonel Mustard, when it comes to computers, they themselves how would the computer facilities respond? in his own computer room-the scene of a are part of security." What alternative computer facilities could be recent crime. Is security tight enough co prove Campbell heads a unit of DCRT charged used? What critical computer systems should that the user wasn't responsible' D with implementing federal computer security be restored first: patient information' payroll? policies at NIH. His group conducts a highly grant disbursement? These are tough ques­ visible education program that includes lec­ tions, and answers are expensive to plan and Roberts Joins Inn Board tures like the one given by Dr. Sanford implement. NIH is one of the first govern­ Sherizen at the recent Computer Security ment agencies to move aggressively towards a Distinguished journalist Cokie Roberts is Awareness Day. Awareness Day this year also comprehensive contingency plan. Campbell's the newest member of the board of the Chil­ featured a briefing for NIH executive officers group has made such preparation a top pri­ dren's Inn at NIH. Noted for her incisive and a 2-day intensive workshop for selected ority, but the NIH community should be news reports and analysis for National Public NIH security coordinators. The brightly col­ aware that such measures will not be fully Radio (NPR), Roberts is also a network corre­ ored computer security posters and "pop-up" implemented for another 6 to 12 months. spondent for ABC News. desk calendars chat can be seen around the If security seems too much of a hassle, says Roberts joined NPR in 1978 as the sta­ campus are also a part of this education Campbell, consider these questions: Could you tion's congressional correspondent, making a program. afford to lose the critical information on your name for herself with her comprehensive Campbell's office is primarily concerned system completely? Would you want to take reports on voter concerns during presidential with seeing that information at NIH is the time to reenter it from hard copy? Would and congressional election campaigns. From secure-secure from outside prying or tamper­ you want to be held responsible for sensitive 1981 to 1984, she cohosted The Lawmakers, a ing, secure from catastrophic destruction. To information that falls into the wrong hands? weekly public television program on Congress. this end, he works with the security coordina­ Computer information deserves the same care Prior to joining NPR, Roberts was a tors in the ICDs and at the five major NIH and protection from contamination that lab reporter for CBS News in Athens, Greece. She computer facilities (DCRT, NLM, CC, experiments do. also produced and hosted a public affairs pro­ NIEHS, and NCI-Frederick) to perform risk For information on computer system safe­ gram on WRC-TV/Washington, D.C., and analyses on the computer systems. These risk guards, contact Campbell, 496-4885. produced Serendipity, an award-winning pro­ analyses help identify vulnerabilities in the gram on KNBC-TV/Los Angeles. D page 6 The Record July 7, 1992

ALTERNATIVES (Continued from Page 1.) sponsored by the Fogarty Internacional Center and a subsequent request for applications to establish "international cooperative biodiver­ sity groups" as examples of how NIH is exploring new ways to carry out its mandate of improving the health of all people. Part of the money will be used to help alternative practitioners "develop meth­ odologies so that their results are interpretable and analyzable," he said. Groft said NIH defines "unconventional medical practices" as "a diagnostic or therapeutic technique that is presently outside the field of conventional medical research." Dr. Stephen Groft (foreground), acting head of NIH's new Office for the Study of Unconventional Medical NIH will offer technical assistance and finan­ Practices, presides over the recent ad hoc conference on alternative practices. He was given a rousing ovation at cial support for the study of efficacy of these meeting's end, and called the session deeply inspiring. practices. Addressing the 20-member ad hoc advisory board at its first meeting, Groft said, "I have Wiewel, executive director of People Against medical schools and medical-affiliated asked each panelist to consider what may be Cancer in Orcho, Iowa. "Let's get real-this is institutions. fertile areas for examination. They could be an ingrained bureaucracy. We've got to break As part of the education process, briefings general areas or specific treatments." He the bureaucracy of the past and establish a on methodologies to evaluate the effectiveness pointed out that there are 250,000 plants on new order." of unconventional medical practices and an Earth, and said that mankind has studied only Former Congressman Berkley Bedell of explanation of how the NIH peer review sys­ about 1,100 of them. Iowa, who had sponsored funding for the new tem works were presented to the panel and The panel, composed of experts in various NIH office, commented, "I have become frus­ public. methods of alternative medicine and recom­ trated by conventional medicine shutting out Members of the public testifying at the mended by !CDs, was convened to identify the study of alternative treatments." hearing covered a wide variety of topics in the issues and then help set up an official Other panelists were more optimistic. "The their comments. Some related their own advisory council. The latter group will help attitude at NIH is beginning to change," said experiences as patients of unconventional med­ NIH screen and select the procedures to inves­ Dr. Joseph Helms, president of the American ical practitioners. Others had recommenda­ tigate unconventional medical practices and Academy of Medical Acupuncture Programs, tions for the new NIH office and advisory recommend a research program to test fully UCLA Extension, Berkeley, Calif. He cited panel ranging from how the new office should the most promising ones. Each ICD has the NIH Office of Intramural Research and be established to topics chat should be investi­ assigned a contact person to maintain liaison the Fogarty International Center as working to gated most quickly. with the new office. integrate acupuncture into other NIH treat­ The advisory group is scheduled to meet Much of the first day's meeting was devoted ments. again next autumn. D to discussions by panel members on how best Dr. Barrie Cassileth, a psychologist and to determine which "unconventional" practices medical sociologist from Chapel Hill, N.C., offer the brightest prospects for verifiable agreed that attitudes at NIH are changing. results. But, she added, "We must never give up the "Mose groups agree on the need for double­ goal of documentable, observable results." blind clinical trials with the use of a placebo," Dr. Dean Ornish, director of the Preventive said Dr. Jennifer Jacobs of Edmonds, Wash., Medical Research Institute, Sausalito, Calif., who practices homeopathic medicine at the said, "I understand the difficulty of getting University of Washington. There has never funding-but NIH is supporting much of my been research published about clinical trials research. NHLBI is willing to fund it if it with homeopathic research, she pointed out, proves of efficacy and value." and suggested a cost-effectiveness study on He continued, "Trying to separate what homeopathy vs. conventional medicine in works from what doesn't is an important terms of days of work lost, quality of life, and task." other aspects. Wiewel added, "The general view in the Other panelists agreed on the need to pro­ medical establishment is we're losing the war duce confirmable results chat can be on cancer and AIDS. The people who have Three employees were recognized by NIH's automatic duplicated. However, concern was expressed survived unconventional treatment merit data processing/extramural coordination committee that the traditional peer review system in immediate attention." He proposed a perma­ recently for their outstanding contributions to the extramural computing community. They are (from grading potential grants has no practitioners of nent Office of Alternative Medicine at NIH. l) Lois Reed, retired from NIDDK; Carolyn alternative medicine and it would be impos­ Dr. David Eisenberg of Beth Israel Hospital McHale, NIAMS; and Sue Feldman, OD. sible for them to compete successfully for a in Boston suggested that the committee "help grant under the current review system. facilitate" the establishment of "databases, "People from the alternative community meta-analyses [and} different ways of review­ aren't on NCI peer review boards," said Frank ing the literature" that could be used by page 7 The Record July 7, 1992

NIDDK's Maureen Harris Honored with Kelly West Award Dr. Maureen I. Harris, director of of new classification and diagnostic criteria for NIDDK's National Diabetes Data Group diabetes, which have since been adopted by (NDDG) and chair of the NIDDK epidemiol­ the World Health Organization. She also ogy coordinating committee, is the 1992 directed development of Diabetes in America, a recipient of the American Diabetes Associa­ comprehensive compilation of epidemiologic tion's Kelly West Award for outstanding data on diabetes and its complications, pub­ research in diabetes epidemiology. lished by NDDG in 1985. In addition, Harris The award was presented at the association's helped coin the term "impaired glucose toler­ annual scientific meeting in San Antonio, ance" to describe the condition of individuals where Harris spoke on "Undiagnosed whose glucose tolerance is less than that of the Noninsulin-Dependent Diabetes: Clinical and normal population but insufficiently abnormal Public Health Issues." to be diagnosed as diabetes. According co Dr. Phillip Gorden, NIDDK Dr. Robert Silverman, chief of NIDDK's director, "Maureen Harris is widely recognized Diabetes Programs Branch, said Harris' work in the research community for her special con­ has contributed significantly to medical under­ tributions co our understanding of the standing of the prevalence of diabetes and its epidemiology of diabetes. NIDDK is proud of complications in the U.S. and has helped her recognition and her accomplishments." determine the national agenda for diabetes Harris' research on the epidemiology of dia­ research. betes has resulted in more than 60 publica­ Harris received a bachelor's degree in chem- tions in the past decade and has included Dr. Maureen Harris istry from George Washington University in studies on the prevalence of diabetes in U.S 1964, a Ph.D. in biochemistry from Yale ethnic groups, diagnostic criteria and screen­ made a unique and outstanding contribution University in 1968, and a master's degree in ing for diabetes, population-based studies on to the epidemiology of diabetes and its com­ public health from Johns Hopkins University diabetes complications, and health care utiliza­ plications, both in the U.S. and around the School of Public Health in 1975. She joined tion by patients with the disease. She also is a world." NIDDK as a research fellow in 1968, becom­ frequent speaker at diabetes meetings and a Among other contributions, Harris' work ing director of NDDG in 1977, director of consultant co numerous federal and nonfederal revealed chat as many as half of Americans the diabetes epidemiology research program in programs relating to diabetes. with diabetes are unaware they have the dis­ 1984, and chair of the NIDDK epidemiology Dr. Ronald Klein, professor of ophthal­ ease and that the prevalence of self-reported committee in 1989. mology at the University of Wisconsin diabetes among Mexican Americans is more The Kelly West Award is named for the Medical School at Madison and chairman of than double the rate for the U.S. population lace Dr. Kelly West, a pioneer of diabetes the ADA's council on epidemiology, which as a whole. epidemiology, whose 1978 textbook on the unanimously selected Harris out of 12 candi­ Harris also played an important role in the subject is considered a founding work in the dates for the annual award, said, "She has development by the NDDG in the lace 1970's field.-Eleanor Mayfield D

DRG's Gertrude McFarland Receives NANDA Commendation research. Her efforts to improve clinical nurs­ Dr. Gertrude K. McFarland has received ing practice and to advance the knowledge the Award for Unique Contribution co the base of the nursing profession have been recog­ Advancement of Nursing Diagnosis from the nized by four American Journal of Nursing North American Nursing Diagnosis Associa­ (AJN) Book of the Year Awards, the AJN tion (NANDA). She was recognized for her Classic Book Award, the Nursing Life Out­ "international leadership in advancing the standing Book for Nurses Award, and the knowledge base of the nursing profession," University of Cincinnati Distinguished and for "her numerous publications." Alumnus Award. She has also been awarded McFarland is the scientific review administra­ status as a fellow of the American Academy of tor of DRG's nursing research study section. Nursing. The NANDA develops, refines, and pro­ McFarland is internationally known for her motes a taxonomy of nursing diagnostic nursing publications, delegation leadership terminology of general use to professional abroad, and multiple national and interna­ nurses. The award won by McFarland is given tional presentations on nursing diagnosis, to a professional nurse who has made signifi­ psychiatric mental health nursing, and admin­ cant contributions to facilitating the use and istration. Her six current textbooks have been testing of nursing diagnoses in clinical prac­ translated into Japanese, French, Spanish, Por­ tuguese, Italian, and Taiwanese. She serves on tice, for dissemination of nursing diagnoses Dr. Gertrude K. McFarland information through publications and presen­ the Journal of Psychosocial Nursing and Mental tations, and for advancing the knowledge base McFarland has received many honors, Health Services editorial board. of nursing diagnoses through research and including the NIH Award of Merit for She obtained her master's degree in nursing theory-building. It was presented at the asso­ exemplary service to the extramural research from the University of California, San Fran­ ciation's 10th International Conference on the program of the NIH and the nursing com­ cisco, and her doctorate in nursing science Classification of Nursing Diagnoses in San munity, and the U.S. Public Health Service from Catholic University in Washington, Diego recently. Special Recognition Award for clinical D.C. □ The Record Julypage 7,8 1992

SCHISTOSOMIASIS

(Continued from Page JJ

immune system cells known as macrophages. A greater understanding of how nitric oxide production is inhibited could lead to the development of a vaccine or new drug therapies against the disease. Scientists expect that learning more about how parasites commandeer the immune response will reveal insights into the immu­ nosuppression that accompanies many other chronic infections as well. "We are only at the beginning of our understanding of how patho­ gens can employ the biologic activities of host cytokines to support their own physiology and survival," says Dr. Alan Sher, chief of the immunology and cell biology section of the Schistosomiasis researchers (from l) Drs. Alan Sher, Isabelle Oswald, Stephanie James, Ricardo Gazzinelli, Laborarory of Parasitic Diseases. and Thomas Wynn work in the cell biology section of NIA/D's Laboratory of Parasitic Diseases. The study of schistosomiasis has helped clarify this parasite-host dynamic. Schistoso­ mal worms burrow into the skin of a person Parasitic Diseases, nitric oxide helps the GOVERNOR bathing or working in infested water and, body's defenses by inactivating enzymes that once in the body, can live undetected in the schistosomula and other invading organisms (Continued from Page JJ veins of the bladder and intestines for 5 years need for crucial cellular functions such as Schaefer, known for his unique candor, be the or more. There, pairs of male and female DNA replication. first Maryland governor to visit NIH. "He has worms, intertwined like vines, produce up· to Significantly, even tiny amounts of the come to be known as a pacesetter," she said. 3,500 eggs a day. Many eggs wend their way three cytokines seem to work in concert to "We're pleased that the governor and his to organs such as the liver, brain and lungs. prevent worm killing by the nitric oxide office and staff have taken an interest in our They wreak havoc by clogging tiny capillaries mechanism, Oswald and her colleagues report work here. We look forward to a new begin­ and blocking blood flow as the body forms in the June 1 edition of the Journal of ning. We'd love it if 'Dr.' Schaefer's visit cysts and scar tissue around the eggs in an Immunology. would inspire other governors." attempt to wall them off. Oswald, along with James, Dr. Thomas Paraphrasing a popular advertisement, Early in infection, people with Wynn, Dr. Ricardo T. Gazzinelli, and Sher, Healy said NIH is like General Electric: "We schistosomiasis, many of them children, suffer also has discovered that the cell that secretes try to bring good things to life ... Research is fevers, chills, and abdominal and lower back nitric oxide, the macrophage, needs two sig­ an investment. [NIH} can be the leverage; the pain. Untreated patients with long-term nals to be turned on-interferon gamma and return will come in jobs." infestations can develop urinary tract obstruc­ endogenous TNF-alpha-and that IL-10 can And, for the curious, Schaefer said his other tions and jaundice; many patients die from block the production of endogenous TNF­ "favorite" job was mayor of the city of cirrhosis of the liver, bladder tumors, or alpha. Now they are trying to find out if IL-4 Baltimore.-Carla D kidney failure. and TGF-beta turn off nitric oxide production The mouse model has been key to under­ in the same way. Garnett standing how schistosomiasis progresses. Further experiments will demonstrate Bond Raffle Winners Picked Researchers know, for example, that mice whether this laboratory observation holds up with schistosomal infections produce higher in the live mouse, where the amount of Winners of the NIH Savings Bond Drive than normal levels of certain cytokines secreted cytokines reaching cells may be far less than raffle held on the patio of Bldg. 31 on June by T-helper cells. that used in the test tube. And although sci­ 25 were: Richard Bragg of NCI, who won the In a paper published last October, Sher and entists have not yet found that human Canvasser's Raffle prize of a $500 Savings his group reported that one of these cytokines, macrophages use the nitric oxide killing mech­ Bond donated by the NIH Federal Credit interleukin-10 (IL-10), first appears in mice 7 anism, many researchers think it highly likely Union; Janice Ward of NLM, who won a $50 to 8 weeks inro the infection when the worms that a human system analogous to that seen in bond donated by Crestar Bank; Anadel Ben­ begin laying eggs. The actual mechanisms by mice exists. jamin of NCRR, who won two tickets to which such cytokines render the immune sys­ If this proves to be the case, cytokine-based Busch Gardens, donated by R&W; and tem defenseless against schistosomula, therapies may someday enable doctors to beat Ricardo E. Roberts, Jr. of NCRR, who won however, have remained unclear. schistosomula at their own game: manipulat­ an Entertainment '92 Book, donated by Now, in test-tube experiments with mouse ing the immune response to their own R&W. The last three winners were entered in macrophages, Dr. Isabelle P. Oswald and her advantage. D the bond-purchasers portion of the raffle. D NIAID colleagues in Sher's section have found out how the parasite subverts the host's reg­ ulatory mechanisms to its own advantage. It appears that three T-helper cell cytokines­ IL-10, IL-4 and transforming growth factor beta (TGF-beta)--all block nitric oxide pro­ duction. As first reported in 1989 by Dr. Stephanie L. James, also in the Laboratory of page 9 The Record July 7, 1992

Commuter News Update

The Montgomery County department of transportation presented an outstanding achievement award to the National Cancer Institute at the transportation awards cere­ mony held recently during National Transportation Week. Cynthia Rooney, NCI program administrative officer and employee transportation coordinator for the Executive Plaza location, accepted the plaque on behalf of the institute. "NCI has been an active participant in the promotion of carpooling, vanpooling and tran­ sit use for the past 4 years," said Susan Hallman of the Montrose and Executive Com­ muter Service Center, who nominated NCI for the award. NCNR's Dr. Carolyn Murdaugh has received the NCI, in cooperation with the commuter Award of Merit from the American Heart Associa­ center, has held transportation information tion for her contributions to developing AHA 's days in the lobby of the Executive Plaza South A new transportation display, located in the park­ national program. She has been active in AHA at Bldg. resulting in a 170 percent increase in ing office in Bldg. 31, features commuter maps and the local, state, and national levels since 19 7 0, carpooling there; vanpoolers increased by 60 free brochures. serving on the national board of directors and percent in the past year, and transit use is up chairing the council on cardiovascular nursing, by 329 percent. NCI boasts more than 50 per­ Pedestrian Traffic Rises with the Mercury among many other roles. A senior investigator in cent participation in the commuter program NCNR's intramural program, Murdaugh heads the Remember that pedestrian traffic on campus by its employees assigned to the Executive increases dramatically during summer months. Laboratory for the Study of Human Responses to Plaza area. Health and Illness and directs a major study of When driving, remember the campus speed caregivers of elderly men with dementia, part of the New Transportation Display limit of 25 miles per hour, use extreme cau­ Honolulu Heart Program. The Division of Security Operations, tion when the Campus Shuttle Bus is boarding Employee Transportation Services Office, has or unloading passengers, and yield to all installed a transportation information display pedestrians. FAES Announces Fall Classes in the corridor of the parking office, Bldg. The FAES Graduate School at NIH 31, B3 level. The display houses large maps of Lift-Equipped Buses Acquired announces the schedule of courses for the fall the Metro and Ride-On bus systems and the The Transportation Branch recently pur­ semester. The evening classes will be given on Metrorail system as well as maps for other chased two lift-equipped buses, which can the NIH campus. local area transit systems. Free brochures and accommodate 1 disabled passenger and 14 Tuition is $60 per credit hour, and courses schedules are also available there. For more seated passengers, each. The buses will operate may be taken for credit or audit. Courses that information, call or visit ETSO, 402-RIDE, on the Westwood Shuttle route. For more qualify for institute support as training should Bldg. 31, Rm. B3B08. information, call 496-3426. be cleared with the supervisors and admin­ istrative officers as soon as possible. Both the vendor's copy of the training form and the FAES registration card must be submitted at the time of registration. Courses are offered in biochemistry, biol­ ogy, biotechnology, chemistry, computer science, immunology, languages, mathema­ tics, medicine, microbiology, pharmacology, psychology, psychiatry, statistics, toxicology, administration and courses of general interest. It is often possible to transfer credits earned to other institutions for degree work, and many courses are approved for AMA category I credit. Classes begin Sept. 21, mail registration ends Aug. 7, and walk-in registration will be held Sept. 9-15. Fall catalogs will be available in July in the graduate school office, Bldg. 60, Suite 230; the foundation bookstore, Bldg. 10, Rm. BlLl0l; and the business Cynthia Rooney, NCI program administrative officer, accepted a plaque given to the institute for its success in office, Bldg. 10, Rm. B1Cl8. To have a cata­ recruiting employees to carlvanpools, or public transportation. The citation was presented by (from l) Graham log sent, call 496-7977. D Norton, director of Montgomery County's department of transportation; Neal Potter, county executive; and O. James Lighthizer, Maryland's secretary of transportation. The Record Julypage 7,10 1992

PHS Honors NIH Employees for Outstanding Achievements

NIH staffmembers were recognized for their Mattie L. Jackson Dr. Nathan Watzman outstanding achievements and contributions at the 1992 Public Health Service Honor Awards Ceremony held June 25 at Wootton High Personnel Staffing Specialist Chief, Clinical Sciences Review Section Referral and Review Branch School auditorium. Dr. James 0. Mason, assist­ Recruitment and Employee Benefits Branch "For outstanding contributions in revising the Executive Secre­ Division of Personnel Management Divisiontary's Handbook of Research and the researchGranes grant and fellowship application ant secretary for health, assisted by Dr. Antonia Office"For ofdedication Administration to the students and student programs of the forms used by the entire Public Health Service." Novello, U.S. surgeon general, and Dr. Ber­ NationalOffice of Institutes the Director of Health and Public Health Service." nadine Healy, NIH director, presented the PHS SPECIAL RECOGNITION AWARD Mary L. Miers following awards. Dr. James M. Dambrosia PHS SUPERIOR SERVICE AWARDS Chief, Legislative and Analysis Branch Supervisory Mathematical Statistician Dr. Vida H. Beaven Office of che Director Mathematical Statistics Section National"For outstanding Institute service of Neurological in collaborating Disorders with staffof and NIMH in Biometry and Field Studies Branch Strokecoordinating the preparation of the Neuroscience and Behavior por­ Assistant"For innovative Director management for Program of critical Coordination NIH-wide issues and tion of the NIH Strategic Research Plan." Division of Intramural Research unprecedentedOffice of cheleadership Director of the outstanding NIH public advisory National"For sustained Instituteexcellence of Neurological and innovation Disordersin the application and of system resulting in increasedfemale and minority representation." Dr. Edward J. Sondik Strokestatistics to the design and analysis of research studies in neurology, and to medicine in general." Dr. William J. Bloc Deputy Director Dr. Irene A. Eckstrand Division"For vision, of Cancer innovative Prevention leadership, andexemplary Control service, and an Chief, Biostatistics Branch Nationalindefatigable Cancer spirit in Institute creating and implementing a national cancer Epidemiology and Biostatistics Program control program." Healch Scientist Administrator Division of Cancer Etiology Genetics"For outstanding Program contributions and consistent commitment to the "For sustained outstanding research in the UnitedStates and Dr. Stephen J. Suomi Nationalabroad that Cancer has provided Institutenew insights into the causes and ultimate Nationaladministration Institute of GenBank of General and the Medicalsuperb efforts Sciences to promote pri­ prevention of cancer." mary and secondary school science education." Dr. George P. Chrousos Chief, Laboratory of Comparative Ethology Lily 0. Engstrom Division of Intramural Research National"For contributions Institute to ofthe Child understanding Health of and the developmentHuman of Head, Section on Pediatric Endocrinology behavior,Development using a non-human pri,nate model to establish the large Assistant Director Developmental Endocrinology Branch role which genetics plays in this development." Office"For ofexceptional Extramural enterprise Research and extraordinary dedication in National"For pioneering Institute studies of onChild the regulation Health ofand Human Officedeveloping of thethe National Director Institutes of Health Financial Management Developmenthypothalamic-pituitary-adrenal axis function, leading to new Dr. Carol E. Vreim Plan in response to Congressional directives." insights into the pathophysiology of adrenal diseases and novel diag­ NHLBI Group A ward nostic strategies." Health Scientist Administrator Linda Gardner Dr. George Counts Office of the Director Division"For outstanding of Lung contributions Diseases to the programs of the Division of NationalLung Diseases, Heart, NHLBI; Lung, particularly and Blood in the Institute area of pulmonary Contract Specialist Supervisory Medical Officer vascular diseases." Contracts Operations Branch Clinical Research Management Branch Dr. Edward Lakatos Treatment Research Program Marianne S. Wagner Division of Extramural Affairs Division"For outstanding of AIDS direction of new initiatives and activities of the AIDSNational clinical Institute trials system, of Allergy and exceptional and Infectious efforts to enhanceDiseases the Personnel Officer Mathematical Statistician participation of medically underserved populations." Biostatistics Research Branch Personnel Management Branch Dr. Jeffrey Probstfield Geoffrey E. Grant Office of Administrative Management Division of Epidemiology and Clinical Applications Office"For ofoutstanding the Director leadership qualities, exemplary pe,formance, andNational contributions Cancer which Institute have resulted in material improvement in Medical Officer Granes Policy Officer human resources management to the Public Health Service." Clinical Trials Branch Office of Extramural Programs Clinical Applications and Prevention Program Office of Extramural Research Dr. Sharon M. Wahl "For exceptional dedicated pe,formance in the area of grants Division"For outstanding of Epidemiology contributions and to the Clinical conduct ofApplications SHEP, a major managementOffice of the poli cyDirecror, especially for invaluable contributions to the clinical trial of tremendous public health importance, evaluating NIH Indirect Cost Study." treatment of isolated hypertension in the elderly." Chief, Cellular Immunology Section Laboratory"For outstanding of Immunology leadership and exceptional achievements in characterizingNational Institute cellular andof Denealmolecular Research mechanisms of chronic inflam­ matory diseases." Dr. Michael D. Walker

Director, Division of Stroke and Trauma National"For an Instituteoutstanding ofcareer Neurological in the PHS andDisorders for exceptional and Strokeaccomplishment of the PHS mission." page 11 TheRecord July 7, 1992

Dr. John A. Hanover Joyce Piotrowski Crystal L. James

Research Chemise Program Coordinator Lead Administrative Technician National"For the Institutesuccessful experimental of Diabetes approaches and Digestive that have andledto the DivisionDr. Polly of SagerAcquired Immunodeficiency Syndrome Office"For ofcontributiom Administrative and comistent Management commitment to the provision of Kidneyidentification, Diseases cloning and expression of proteim of the nuclear pore administrativeNational Institute services inof the General most friendly, Medical efficient, Sciences and cooperative complex." ,na.nner." Toxicologist Dr. Jeanne N. Keeley Division"For an ofexceptional Acquired and Immunodeficiency dedicated group effort to Syndrome expeditiously Barbara Z. Kempner design innovative and effective methods to meet the critical needs of children with AIDS." Chief, Physiological Sciences Review Section Supervisory Granes Management Administrator Dr. Kenner C. Rice Referral"For dedication and Review and persistence Branch in providing leadership and direc­ Granes Management Branch tionDivision to the developmentof Research of theGranes NIHIADAMHA Comultant File." Division"For sustained of Extramural outstanding Activities performance in carrying out the many Chief, Laboratory of Medicinal Chemistry demandingNational functiomInstitute of ofthe Allergyposition of and Supervisory Infectious Grants Diseases Manage­ OD Group Award ment Administrator for the Grants Management Branch." National"For pioneering Institute contributiom of Diabetes to the andchemistry Digestive and pharmacology and Dr. Charles R. McCarthy Kidneyof centrally Diseases active drugs." PHS EQUAL OPPORTUNI1Y Dr. Pamela Rodgers-Johnson ACHIEVEMENT AW ARD

Director Dr. Joseph L. Bryant Office for Protection from Research Risks OfficeDr. Joan of Extramural P. Porter Research Visiting Scientist Laboratory of Central Nervous System Studies Chief, Animal Care Unit Basic Neurosciences Program Intramural"For exemplary Research contributiom Program to equal employment opportunity Executive Coordinator for Inceragency Affairs Division of Intramural Research Nationaland affirmative Institute action programsof Dental of theResearch National Imtitute of Dental Office for Protection from Research Risks National"For elucidation Institute and of characterization Neurological of Disordersthe human T-cell and type I Research and the National Imtitutes of Health." Office"For ofoutstanding Extramural leadership Research in developing and coordinating pro­ retrovirusStroke etiological role in neurologic and systemic disease; pri­ mulgation of the Federal Policyfor the Protection of Human marily tropical spastic paraparesis and polymyositis." OUTSTANDING PHS EMPLOYEE WITH A Subjects." DISABILI1Y Dr. J. Craig Venter Dr. Joseph K. McLaughlin Susan V. Smith

Research Physiologist Epidemiologist Receptor Biochemistry and Molecular Biology Section Biologist Analytical Studies Section National"For development Institute of ofa novel Neurological strategy to isolate Disorders key identifying and Laborarory of Neurophysiology Bioscaciscics Branch Strokeregiom, expressed sequence tags, of more than 2000 genes that work National Institute of Neurological Disorders and Epidemiology and Biostatistics Program "For outstanding contributiom to the Laboratory of Neurophysiol­ within the human brain." Strokeogy in the use of FACS systems to study the development of cellular Division"For outstanding of Cancer research Etiology in the etiology of renal cancer, occupa­ physiology in the CNS." tionalNational cancers, Cancer and for Institute important contributiom to epidemiologic Dr. Sheila H. Zahm methods." PHS VOLUNTEER AWARD Dr. Lynne M. Mofenson Epidemiologist Annette R. Hanopole Occupational Studies Section Environmental Epidemiology Branch Associate Branch Chief for Clinical Research Epidemiology and Biostatistics Program Granes Management Specialist Pediatric, Adolescent and Maternal AIDS Branch Division"For outstanding of Cancer contributiom Etiology to the development of exposure Office"For ofexemplary Program initiative Activities and dedication in wluntary service National"For outstanding Institute contribution of Child to Health development, and implementation,Human assessmentNational methods Cancer in Instituteoccupational epidemiology and in the evalua­ Nationalorganizing aInstitute recycling projectof General aimed at Medical supporting Sciences an off-site NIH andDevelopment dissemination of infonnation concerning the evaluation of tion of the role of pesticides in cancer etiology." daycarefacility. " therapies which are useful in the treatment of children with HIV/ AIDS." PHS SPECIAL RECOGNITION AWARD (For Productivity) NIAID Group A ward Patricia L. Scullion Pediatric Initiative Group Leo F. Buscher, Jr. Employee Development Specialise Personnel Management Branch Dr. Patricia Fast Office of Administrative Management Chief, Granes Administration Branch Office"For ofdedicated the Directorefforts and goodwill to pediatric patients at the Office"For ofleadership Administrative in initiating Management and implementing innovative man­ NationalChildren's Inn,Cancer National Institute Imtitutes of Health, and those affiliated Medical Officer Nationalagement procedures Cancer which Institute resulted in improved accuracy and with Special Love, Inc." Dr.Division Rodney of Acquired Hoff Immunodeficiency Syndrome timeliness of research grant awards, 11 DISTINGUISHED SERVICE MEDAL

Epidemiologist ASH SPECIAL CITATION Dr. Hollis B. Brewer, Jr. Tina Johnson Division of Acquired Immunodeficiency Syndrome Shirley P. Hopkins Chief Health Specialist Molecular Disease Branch Staffing Assistant (Typing) Dr.Division Jack of Killen Acquired Immunodeficiency Syndrome Division"For outstanding of Intramural contributiom Research to the field of lipoprotein metabo­ Entry Level Recruitment Section Nationallism and elucidation Heart, Lung, of apolipoprotein and Blood structural Institute motifs which Recruitment and Employee Benefits Branch profoundly affect human tramport in health and disease." Deputy Director Division of Personnel Management Dr.Division Bonnie of Acquired Mathieson Immunodeficiency Syndrome Office"In recognition of Administration of your performance and dedication to the NIH andOffice its student of the andDirector clerical employment programs." (Continued on Page 12) Microbiologist Division of Acquired Immunodeficiency Syndrome The Record Julypage 7, 12 1992

(Continued from Page 11) NCl's Klee Cited by WISE Dr. Claude E. B. Klee, chief of NCI's Lab­ Dr. Peter L. Frommer oratory of Biochemistry, recently received the Deputy Director distinguished Women in Science and Engi­ National Hean, Lung, and Blood Institute "For sustainedexceptional service and leadership in the develop­ neering, Inc. (WISE) Lifetime Achievement ment and administration of DHHS biomedical research programs." Award. This annual award recognizes signifi­ cant contributions to science and acknowledges Dr. John I. Gallin accomplishments in advancing the careers of Director other women scientists. Division of Intramural Research WISE identified Klee as a "major figure in National Institute of Allergy and Infectious Diseases "For outstanding careercontributions to the scientific mission and research goals of the National Institute of Allergy and Infectious DiJeases." Dr. Steven A. Rosenberg Chief Surgery Branch National Cancer Institute "For uniquely insightful application of basic immunology to the development of new and effective cancer treatment, gene therapy and vaccine roearch." Delores Merrick discussed her organization's efforts MERITORIOUS SERVICE MEDAL to educate Blacks with diabetes on the use of proper Dr. Marlene N. Cole management techniques, including diet, at the Deputy Director NIDDK meeting, "Diabetes in Black Americans: Veterinary Resources Program Community Intervention and Education Programs." National Center for Research Resources Merrick, diabetes program associate for the Health "For-dynamic leadership resulting in the successful reorganization Promotion Council of Southeastern Pennsylvania, and revitalization of VRP, the largest intramural component of directs a diabetes education program for inner-city NCRR." Blacks. The recent meeting was sponsored by the Dr. William S. Driscoll joint diabetes mellitus interagency coordinating com­ Dr. Claude Klee Chief mittee and the National Diabetes Information Disease Prevention Section Clearinghouse coordinating panel. the scientific programs of the NIH and in bio­ Epidemiology and Oral Disease Prevention Program chemistry throughout the world_." Her Disease Prevention and Health Promotion Branch presence at NCI has greatly enhanced the pres­ National Institute of Dental Research "For sustainedexcellence in advancing the prevention research tige of NIH throughout the biomedical com­ programs of the NIDR and the NIH through exemplary clinical munity, the citation stated. Over the last trials and the promotion of scientifically-basedpublic health decade Klee has been investigating the way in programs." which calcium regulates essential cellular Dr. Jay H. Hoofnagle reactions. Division Director In addition to recognizing her accomplish­ Division of Digestive Diseases and Nutrition ments in the laboratory, WISE acknowledged National Institute of Diabetes and Digestive and Klee's strong support for women seeking to Kidney Diseases advance their scientific careers. She has "For research advances in viral hepatitis and demonstrated1nan­ agerial skills." encouraged female technicians to undertake independent projects leading to their advance­ Dr. Kurt W. Kohn ment within the scientific community. She has Laboratory Chief also worked to help female postdoctoral fel­ Laboratory of Molecular Pharmacology lows obtain desirable positions after National Cancer Institute "For significant accomplishments in molecular pharmacology tech­ completing their training. nology, for pioneering studies on Topoisomerase II inhibitors, and for More recently, Klee was elected to the leadership of the Laboratory of Molecular Pharmacology." National Academy of Sciences' Institute of Medicine. D

Dr. Ada Sue Hinshaw, director of the National Center for Nursing Research, recently received the Nonsmokers Needed for Study Distinguished Service Citation from the University A study of personality and physiological of Kansas Alumni Association, and also an honor­ responses being conducted at the Uniformed ary doctorate from the University of Nebraska. Services University of the Health Sciences Both awards recognize her leadership role and many needs nonsmoking males and females, 18-45 accomplishments in the nursing community. years old, to participate in a 2-hour session. Pay is available. Call (301) 295-3263 and leave a message. D page 13 The Record July 7, 1992

Simeon Taylor Receives ADA Award for Outstanding Science Genome Resource Books Available Dr. Simeon Taylor, chief of the NIDDK Two new resource documents have recently Diabetes Branch, has received the American been produced by the genome program at the Diabetes Association's Outstanding Scientific National Center for Human Genome Research. Achievement Award for 1992. This award is The Genome Report Card is intended to provide given annually to an individual under age 45 an overview of progress toward the 5-year who has made an outstanding contribution to goals of the U.S. Human Genome Project for diabetes research. chromosome mapping and sequencing. Infor­ Taylor received the award on June 22 at the mation in the report card reflects data in the association's annual scientific meeting in San Genome Data Base, GenBank, and primary Antonio, where he also delivered the Eli Lilly publications. Genetic linkage map information lecture, entitled "Mechanisms of Insulin is derived from data reported to the Human Resistance: Lessons from Patients with Muta­ Genome Mapping workshop 10 (HGM10), the tions in the Insulin Receptor Genes." He was Centre D'Etude du Polymorphisme Humain presented with a medal and a check for (CEPH), and the NCHGR Index Map project. $1,000. This edition of the Genome Report Card con­ Dr. Phillip Gorden, NIDDK director, com­ stitutes baseline information. Subsequent mented, "Simeon Taylor has made a major editions can be compared against the March impact on diabetes research and is one of the 1992 edition to mark progress. important reasons why the intramural program The Index Marker Catalog summarizes the of NIDDK is very special." progress of NCHGR's Index Marker Project, Taylor and his group study the molecular Dr. Simeon Taylor which is pare of the center's ongoing program basis of insulin resistance, an important factor to produce a high-resolution genetic linkage in the development of non-insulin-dependent ADA, and the awardee is selected by the asso­ map of the human genome. The framework diabetes (NIDDM). In NIDDM, the pancreas ciation's research grants review panel. map is expected to be useful both to scientists continues to produce some insulin, but the Taylor, a native of New York, received a who are localizing and identifying specific insulin fails to do its job of lowering blood bachelor's degree summa cum laude in chemis­ genes such as those associated with disease, glucose levels. NIDDM is by far the most try from Harvard College in 1969. He then and to scientists completing a high-resolution common form of diabetes, affecting more than entered the M.D./Ph.D. program at Harvard map of the human genome. In the catalog, 90 percent of the 13 to 14 million Americans Medical School, receiving his Ph.D. in biolog­ the set of currently available markers of index with diabetes. ical chemistry in 1974 and his M.D. in 1976. quality (heterozygosity of 70 percent or more) Using recombinant DNA technology, After completing an internship and junior is listed for each chromosome, along with Taylor and his colleagues have identified about residency in internal medicine at Massachu­ marker characterization and information that 15 mutations in the insulin receptor genes of setts General Hospital, Taylor obtained a will allow investigators to acquire and use the patients with rare syndromes of extreme clinical fellowship in endocrinology and markers. insulin resistance. Their studies have provided metabolism at the same hospital. He joined Free copies of these publications may be more information on how healthy insulin NIH in 1979 as a research associate in the obtained by calling 402-0911; fax receptors function. Taylor and his colleagues Diabetes Branch of what was then the 480-2770. □ have illustrated both the complexity of the National Institute of Arthritis, Diabetes, and metabolic process by which insulin binds to Digestive and Kidney Diseases.-Eleanor DCRT Computer Training Classes its receptor and the many ways it may mal­ Mayfield 0 Classes July Dates function. Some patients have fewer than the Maxess 9 normal number of receptors, while others have ENTER BBS 10 Introduction to WYLBUR 13, 15, 17,20,22,24 a normal number of receptors, but the recep- Introduction to PC <--> Mainframe Communication tors are defective. Mutations may also cause NIGMS Grantees Honored with ProComm Plus 14 subtle changes in the receptors' structure, pre­ Developing Data Entry Applications venting them from binding to insulin Two NIGMS grantees, Dr. Seymour Benzer with SAS/FSP 14 normally. and Dr. Mario Capecchi, were recently named MLAB Tutorial 14 DB2: SQL and QMF Selected Topics 15-17 Taylor is an active member of the American winners of the Bristol-Myers Squibb Award for OS/2 2.0 Overview 15 Diabetes Association at both local and national Distinguished Achievement in Neuroscience ENTER MAIL 21 levels. He is past president of the Washington Research. They were recognized for their use Managing information: The area chapter of the association and has also of molecular genetics in studies of nervous sys­ Database Paradigm 21,23,28,30 WYLBURRanges and Patterns 21,28 served on its board of directors. He chaired tem development and behavior. Benzer's Getting Started with C 22,27-29 the association's diabetes research policy com­ research focuses on the fruit fly, and Unix Commands 22 mittee and was a member of the organizing Capecchi's focuses on the mouse. Benzer, the SAS Fundamentals I for Nonprogrammers 23,24 committee for the 14th Congress of the Inter­ James G. Boswell professor of neuroscience at BITNET 23 27-29 the California Institute of Technology, and Programming in Perl national Diabetes Federation held in KaleidaGraph 30 Washington, D.C., in 1991. Capecchi, a professor of human genetics and SAS Fundamentals II forNonprogrammers 30,31 Nominations for the Outstanding Scientific biology at the University of Utah School of Classes are offered by the DCRT Training Achievement Award, which is given annually, Medicine, split a $50,000 award with a third Program, without charge. Call 496-2339 for are made by professional members of the recipient from England. D more information. D page 14 The Record July 7, 1992

Dedrick Wins Founders Award Crews Relamp Campus Byways Dr. Robert L. Dedrick, chief of the chemi­ During the next few weeks, NIH'ers will be cal engineering section, Biomedical seeing workers from the Division of Engineer­ Engineering and Instrumentation Program ing Services' Shops Branch throughout the (BEIP), NCRR, has received the 1992 campus in bucket trucks. That's because DES, Founders' Award from the Chemical Industry in coordination with the ORS advisory com­ Institute of Toxicology. mittee and the Division of Security The award honors Dedrick's 25 years of Operations, has embarked on a project to BEIP research in the developing of physiologic relamp streetlighting units on the NIH pharmacokinetics, primarily working in col­ campus. This project will help to increase laboration with NIH intramural investigators. pedestrian safety and visibility in the parking The cited research was on new approaches for areas, walkways, and on the street, while also cancer chemotherapeutic agents and extending reducing NIH's electric bill, says DES. these techniques to the study of environmental New technology high-pressure sodium contaminants. lamps are more cost-efficient and illuminating "His work has motivated the much broader development of physiologically based phar­ macokinetic modeling in contemporary toxicology," the award statement said. "Dr. Dr. Robert L. Dedrick Dedrick's contributions have formed the basis for the application of these modeling tech­ niques to improving human risk assessment nants, and extrapolating from high dose to and in improving design of toxicology low dose in risk assessment." studies." Dedrick has a special interest in regional Dedrick was honored jointly with Dr. drug administration-infusing a drug to a Kenneth B. Bischoff, professor of biomedical specific body area. He is particularly glad to and chemical engineering at the University of have participated in the theoretical develop­ Delaware. Dedrick came to BEIP in 1966 to ment of intraperitoneal drug administration establish its chemical engineering section. for the treatment of ovarian cancer. "The the­ Bischoffjoined BEIP a year later, part-time, ory has been consistently validated in many while continuing on the faculty of the Univer­ clinical trials, and the therapy appears to show sity of Maryland. activity in terms of surgically confirmed com­ The two chemical engineers worked plete responses in refractory patients. How­ together for several years, with Dr. Daniel ever, the role of the therapy has not been Zaharko, a physiologist with NCI, and others, completely defined in well-controlled clinical to apply engineering principles to the general trials," he says. problem of interspecies extrapolation. Their "Physiologic pharmacokinetics should have 1971 seminal paper "Methotrexate Phar­ an important role in the optimal design and macokinetics" (Journal of Pharmaceutical Sciences use of diagnostic and therapeutic products 60: 1128-33) was selected by the Institute of developed through molecular biology," Shops Branch workers who are re/amping the Scientific Information in 1989 as a citation Dedrick said. "These products are usually campus include (front, from l) Mike Fitzwater, Bradford Brown, Keith Thomas (seated), Jim classic. It presented a pharmacokinetic model large molecules such as proteins and gene con­ predicting distribution in body compartments structs that present special problems for Cook, Raymond Lim-Sharpe, Leroy Scriba, Bill and excretion of the drug in several species, delivery to sites in the body. Our group is Strine, Charles Chambers. At rear are (from !) including humans, over a wide range of doses. now strongly emphasizing the pharmacokine­ Timothy Biser, Alex Sa/ah, Michael Lanovette, Bischoffhas continued his distinguished tics of macromolecules. We are convinced that Marciano Guarin. pharmacokinetics research at Cornell Univer­ a better understanding of their movement in than the existing mercury vapor lamps, sity and the University of Delaware while the body will speed and enhance medical according to the division. The new lamps have Dedrick has continued his in BEIP, where he applications." a softer yellow appearance but provide a high has coaurhored papers with more than 100 The Chemical Industry Institute of Toxicol­ visibility level. The Shops Branch expects to intramural investigators in a number of ogy, located in Research Triangle Park, N.C., complete most of the project this month. institutes on pharmacokinetics and related is sponsored by 50 leading chemical com­ D topics. panies. It performs research on the "Physiologic pharmacokinetics provides a mechanisms of action of toxic substances. Its Study Seeks Couples natural basis for addressing many fundamental Founders' Award has been presented annually The department of medical psychology at and applied problems in pharmacology and since 1978. Previous recipients have included the Uniformed Services University of the toxicology," Dedrick said. "For example, it Dr. Bruce Ames of the University of Califor­ Health Sciences seeks married or cohabiting can be used for extrapolating from one biolog­ nia, Berkeley, Sir Richard Doll of the Imperial couples, age 45 or younger, in which the ical system to another-including in-vitro/in­ Cancer Research Fund, Dr. Robert Weinberg female partner experiences severe premenstrual vivo correlations, optimizing dose schedules of the Massachusetts Institute of Technology, symptoms, to participate in a study of com­ and routes of administration in chemotherapy, and Dr. Charles Heidelberger of the Univer­ munication patterns. Subjects will be paid. assessing exposure to environmental contami- sity of Southern California.-Jim Doherty D For information call (301) 295-3270. D page 15 The Record July 7, 1992

• TRAINING TIPS NHLBl'S Barbara Shepler Retires After 24 Years The NIH Training Center, Division of Per­ Barbara Shepler spent 24 years at the same And the feeling was mutual. Said Shepler, sonnel Management, offers the following desk and witnessed a revolution. A computer "What I've liked the most about my job is the classes: program analyst until her retirement early this people. I guess it will take time to adjust to month, she came to NHLBI in 1968, a time retirement. I'll miss everyone for a while." Courses and Programs Starting Dates when advanced information storage meant key­ Shepler was born in Harrisburg, Pa., and, Management and Supervisory 496-6371 punch machines. on the advice of a friend of her sister's, came Reviewing Other People's Writing 7/28 "The difference between then and now is to work for NHLBI's ISB, then called the Time Management 7/29 like night and day," she recalled. "We've Reports and Evaluations Office. For 9 years, Recognition Secrets-Innovations for Rewarding gone from punchcards to personal computers. she also went to school part-time, obtaining a Today's Workers 8/6 Successful Middle Management at NIH 8/10 It's a huge change." degree through NIH's Upward Mobility Col­ Performance Appraisal Workshop 8/ l 4 Working in NHLBI's Information Systems lege, which was administered by the Univer­ Introduction to Scientific and Medical Editing 8117 Branch (ISB), Shepler helped steward the sity of the District of Columbia. Scientific and Medical Editing 8/ 19 institute through the information revolution. Through the years, she found that her job "Barbara was instrumental in developing evolved dramatically, continually offering her Office Operations and Administrative and maintaining the institute's information the kind of new challenges others have to Systems Training 496-6211 system," noted Ralph Van Wey, Jr., ISB switch offices to find. "I never changed jobs," Guide to Good Grammar 7/28 chief. she laughed. "I went upward instead." "She made many contributions to the Her retirement takes her back to the Har­ Personnel Management 496-6211 institute's information systems. For example, risburg area, where she expects to pursue her Advanced Classification (new course) 8/10 IMPACT System for Personnel Staff 7/20, 8/11 she was very involved in coordination and many interests, particularly gardening, crafts, IMPACT System for MSCs 7/13, 8/17 quality control of our institute-wide personal and travel. IMPACT System for Administrative Staff 7/23, 8/31 computer-based contract management system. One place she plans to visit won't seem too IMPACT System for Professional Staff 7/23, 8/31 "Barbara is well respected and well liked," exotic. 'Tm an avid ice hockey fan," she said. he added, "not only by her coworkers but also "So I'll be returning to Washington to see the Special Courses 496-6211 by the many other people she's dealt with at Capitals play. "-Louise Williams D Break the Smoking Habit 7/16 Mid-Career Financial Planning 7/22 NIH. We're just sorry to see her go."

Sperling Donates 100th Unit Former CC Director Trautman Dies Mansfield Remembered at Service Arnold Sperling, the retired former head of Dr. John A. Trautman, director of the the Clinical Center's patient activities depart­ On June 3, a well-attended memorial service was held in Masur Auditorium for Clinical Center when it opened in f953, ment, recently gave his 100th blood donation Norman D. Mansfield, who had retired last recently died at the age of 90. He and his at the NIH Blood Donor Center. He began February as NIH associate director for wife of 67 years lived in a retirement home in donating blood here in 1963-2 years after research services. He died of cancer May 13 Memphis, Tenn. (see story in May 12, 1992, joining the hospital-and has been giving ever at his home in Potomac. NIH Record). since. He is now a volunteer at the Smithso­ nian, serving as an information specialise in Born in Chicago, Mansfield graduated Trautman joined NIH in 1951 when the from the Illinois Institute of Technology Clinical Center was under construction. Three the Museum of Natural History and the Museum of American History. He is also a and did postgraduate study at North­ years later, he left NIH to become the medical western University. He had a master's officer in charge of the PHS hospital in Fort member of the Resident Associate Program at the Smithsonian. Those interested in giving degree in public administration from Worth, Tex. He served 36 years as a medical blood at NIH should call 496-1048. □ Harvard. officer with PHS. He moved to Washington and joined the During his career, Trautman's research federal service at the Office of Emergency encompassed the use of various agents for Planning in 1959. Later he worked for the Rheumatic Diseases Meeting treatment of cyanide gas poisoning; the use of Office of Economic Opportunity and the artificial fever therapy in the treatment of The arthritis and musculoskeletal diseases National Science Foundation. In 1975, he venereal diseases, leprosy, various inflamma­ interagency coordinating committee is plan­ joined the NIH staff. tory eye conditions, and arthritis; and methods ning an informative meeting on biologics and During his years at NIH, he received for speeding up treatment of various types of rheumatic diseases; it will be held on July 23 many awards, including the Presidential venereal diseases with arsenic compounds and in Bldg. 31, Conf. Rm. 7, from 1:30 to 4 Meritorious Executive Rank Award in 1985 sulfonamide drugs. p.m. There will be two presentations. Dr. and 1991. He was a charter member of the He was a member of the American College Stanley R. Pillemer, NIAMS medical officer, Senior Executive Service. Mansfield is sur­ of Hospital Administrators and the American will talk on "Current Issues in Clinical Trials vived by his wife of 33 years, Marilynn, Medical Association. In 1980, he was induc­ of Rheumatic Diseases," and Dr. Margaret and three daughters, Stephanie, Wendy, ted into the Creighton University Basketball Mitrane, FDA medical officer, will speak on and Heather; his mother, Anne; and his Hall of Fame. "Biologics, Rheumatic Diseases, and the sister, Margo. Born on a farm near Lake Benton, Minn., FDA." For more information, call Sharon in 1902, Trautman is survived by his wife, Louis, 496-0801. D Teresa R. Trautman; four children; 17 grand­ children; and 28 great-grandchildren. page 16 TheRecord July 7, 1992

By Shannon Garnett HBCU Students, Faculty Try Latest Biotechnology Techniques Students and faculty members from 14 his­ observe those procedures and methodologies torically Black colleges and universities that are easily grasped by the students and (HBCUs) recently received a hands-on intro­ those that require greater effort," Parker said. duction to the latest in biomedical technology "This one-on-one relationship allowed the fac­ at the Minority Faculty-Student Partnership ulty to gain a better understanding of how Traineeships in Biotechnology Program. students learn in both classroom and labora­ The 7-day program, sponsored by NINOS tory settings. and FAES, was the first of its kind. It con­ For additional information on the trainee­ sisted of a week-long lecture and laboratory ships, contact Parker, 496-5332. D course introducing selected topics in bio­ technology with special emphasis on recombinant DNA technology. The purpose of Four Join NIGMS Council the program was to attract minority students to careers in brain and nervous system research Four new members have recently been as part of NINOS activities in support of named to the National Advisory General Med­ Black colleges and universities. Faculty-student partners, Dr. Carolyn E. Cousin ical Sciences Council for 4-year terms. They The partnerships paired one undergraduate (l) and Sandra Acholonu from the University of the are Ors. Paul S. Anderson, Jesse B. Barber, science student with one faculty member from District of Columbia, are introduced to the latest in Jr., Alfred G. Gilman, and Leland H. the science department of each HBCU repre­ biomedical technology at the NINDS-FAES spon­ Hartwell; in addition, the Department of sented. From a total of 48 applications, 28 sored traineeship program. Defense has appointed as its ex officio member participants were selected based primarily on to the council Dr. Frederick A. McCurdy. merit and perceived benefit to individual Anderson is vice president for chemistry at undergraduate science programs. Biotechnol- included the propagation of bacteria and the Merck Research Laboratories in West viruses, DNA quantitation, use of restriction Point, Pa. He has served on the NIH study enzymes for cleaving DNA, restriction enzyme section on bioorganic and natural products and mapping, transformation of bacteria with has been a leader in the medicinal chemistry recombinant DNA, identification and isolation division of the American Chemical Society. of recombinant clones, and use of the ELISA Barber was a professor of surgery and neu­ assay. In lectures presented by the instructors, rosurgery, as well as the first professor of the participants also heard about DNA struc­ social medicine, at Howard University College ture and replication, purification and of Medicine until his retirement in 1991. He enzymatic digestion of nucleic acids, nucleic has been active in several professional societies, acid probes and hybridization, and monoclonal including serving as president of the National antibody production. Medical Association. In addition to the classroom discussions, Gilman is the Raymond and Ellen Willie three sessions were held on research oppor­ professor of molecular neuropharmacology and tunities and internships at NIH. The NINOS professor and chairman of the department of plans to continue the traineeship program pharmacology at the University of Texas twice a year, giving each of the 118 HBCUs Southwestern Medical Center at Dallas. In an opportunity to participate. 1989, he received the Albert Lasker Basic Founded by scientists who believe that Medical Research A ward for his research on learning and teaching are essential to the proteins that transmit vital chemical signals in Dr. Lawrence Drummond and Ericka Boone, of evolution of science, the FAES promotes scien­ the cell. Talledega College, isolated cellular DNA, tific research and education by easing Hartwell is a professor of genetics at the extracted plasmids from E. coli and identified communication among scientists and by spon­ University of Washington in Seattle. In 1991, recombinant clones, in the trainees hip laboratory soring formal instruction in the sciences. he received the General Motors Cancer course. All of the trainees were housed at the Research Foundation's Alfred P. Sloan medal ogy training specialists from RIM Nardone National 4-H Center in Bethesda near NIH, and the Hoffman-LaRoche Mattia Award for Associates, Inc. provided the classroom where there was opportunity for students and his research on the cell cycle of growth and instruction. faculty to interact with each other outside of division. "The traineeships provided a unique learn­ the classroom. McCurdy is an associate professor in the ing situation for both faculty and students," Participating schools included Hampton department of pediatrics at the Uniformed said Levon Parker, NINOS EEO officer. University, Howard University, Talladega Services University of the Health Sciences. D "Students gained valuable knowledge and College, Albany State College, South Carolina experience concerning the latest techniques State College, University of the District of and methods in biotechnology that will enable Columbia, Morris Brown College, Bethune­ them to assist fellow students and faculty at Cookman College, Cheyney University, Allen their home institutions." University, University of Maryland-Eastern In the introductory lab course, faculty and Shore, Shaw University, North Carolina Cen­ students isolated cellular DNA, extracted plas­ tral University, and Morgan State College. mids from E, coli, and separated nucleic acids "By working closely with students in labo­ by gel electrophoresis. Other lab experiments ratory sessions, faculty members were able to U.S. GOVERNMENT PRINTING OFFICE 1992-281-825160021