Joan W. Bennett Curriculum Vitae
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Review of Oxepine-Pyrimidinone-Ketopiperazine Type Nonribosomal Peptides
H OH metabolites OH Review Review of Oxepine-Pyrimidinone-Ketopiperazine Type Nonribosomal Peptides Yaojie Guo , Jens C. Frisvad and Thomas O. Larsen * Department of Biotechnology and Biomedicine, Technical University of Denmark, Søltofts Plads, Building 221, DK-2800 Kgs. Lyngby, Denmark; [email protected] (Y.G.); [email protected] (J.C.F.) * Correspondence: [email protected]; Tel.: +45-4525-2632 Received: 12 May 2020; Accepted: 8 June 2020; Published: 15 June 2020 Abstract: Recently, a rare class of nonribosomal peptides (NRPs) bearing a unique Oxepine-Pyrimidinone-Ketopiperazine (OPK) scaffold has been exclusively isolated from fungal sources. Based on the number of rings and conjugation systems on the backbone, it can be further categorized into three types A, B, and C. These compounds have been applied to various bioassays, and some have exhibited promising bioactivities like antifungal activity against phytopathogenic fungi and transcriptional activation on liver X receptor α. This review summarizes all the research related to natural OPK NRPs, including their biological sources, chemical structures, bioassays, as well as proposed biosynthetic mechanisms from 1988 to March 2020. The taxonomy of the fungal sources and chirality-related issues of these products are also discussed. Keywords: oxepine; nonribosomal peptides; bioactivity; biosynthesis; fungi; Aspergillus 1. Introduction Nonribosomal peptides (NRPs), mostly found in bacteria and fungi, are a class of peptidyl secondary metabolites biosynthesized by large modularly organized multienzyme complexes named nonribosomal peptide synthetases (NRPSs) [1]. These products are amongst the most structurally diverse secondary metabolites in nature; they exhibit a broad range of activities, which have been exploited in treatments such as the immunosuppressant cyclosporine A and the antibiotic daptomycin [2,3]. -
The Minutes That Matter Most Tulane Advances the Science & Treatment of Strokes
THE MAGAZINE OF TULANE UNIVERSITY SCHOOL OF MEDICINE | FALL 2015 THE MINUTES THAT MATTER MOST TULANE ADVANCES THE SCIENCE & TREATMENT OF STROKES THE NEW UNIVERSITY MEDICAL CENTER NEW ORLEANS OPENS | TULANE SPORTS MEDICINE’S CLIMB TO SUCCESS TULANE |MEDICINE f you’re like me, every fall you VOLUME 42, ISSUE 2 2015 welcome not only the cooler Senior Vice President and Dean Iweather, but also the return of L. Lee Hamm, MD football season. When I have the Contributors chance, I like to spend my Sunday Sally Asher afternoons watching the giants of the Keith Brannon gridiron. Barri Bronston Cynthia Hayes I see our Tulane faculty in much the Mark Meister same way I see those larger than life Kirby Messinger football stars. They are dedicated, Arthur Nead determined and focused on winning. They battle day in and day out to Fran Simon become the best in their field. But, instead of injuries, our faculty are battling Zack Weaver funding challenges and research delays to ultimately succeed in their goals. It is Photography because of our faculty’s hard work and passion that we can be so proud of our Sally Asher accomplishments. Frank Aymami Paula Burch-Celentano Guillermo Cabrera-Rojo “ I see our Tulane faculty in much the same way I see Cheryl Gerber those larger than life football stars. They are dedicated, Craig Mulcahy determined and focused on winning.” Editing and Design Zehno Cross Media Communications In this issue of Tulane Medicine you will read about two of our programs that represent the best of the best. If you are in New Orleans and have had a stroke, chances are you have asked to receive care from Tulane Medical Center. -
T-Wave [Yearbook] 1984
i1 > I'cJSS V , /. \^ \ s /. x > rjjiwgwyr/J^' < :y li TULANE MEDICAL SCHOOL 1984 ®ulattp ImitptBttg C » "W Wtt f*^ I*? , Digitized by the Internet Archive in 2010 with funding from Lyrasis IVIembers and Sloan Foundation http://www.archive.org/details/twaveyearbook1984edit T-WAVE 1984 TULANE UNIVERSITY SCHOOL OF MEDICINE NEW ORLEANS, LOUISIANA VOLUME 3 YEARBOOK STAFF Donna Chester Editor in Chief Personal Album Childhood Photos Donna Park History of Tulane Senior photos Mickey Puente History of Tulane Bill Shoies The Way It Was George Luck The Way It Was Manny Ramos Admissions Faculty Sam Young PHOTOGRAPHY Senior photos Annelle Ahmed Senior photos Jim Dorcbak larcus Penn Ben Mills Senior Photos Liz Mannino Betty Mortenson Catbv Chicola Assisted all sections Bill Shoies Donna Chester Dave Treen SPECIAL THANKS To Bill Hopkins ofJosten s Publishing Co. for his expertise To Mike Puyau and Colleen Storrs for helping us get and patient counsel. organized when we didn't know which direction we To our generous sponsors and to the parents, companies and were heading. organizations who advertised in this publication. To Cindy for helping us obtain information and historic To Victoria Burten for spending long hours helping us type photos for the History of Tulane Section. the copy for this book. To Parents who contributed pictures for the Childhood Photo section. ^"' 4^4- ¥:^ [If tv^ University Of Louisiana, Medical And Law Departments Tulane University School Of Medicine 1984 THE HISTORY OF TULANE MEDICAL SCHOOL Tulane Medical School had its auspicious beginning as the Medical College of Louisiana in September 1834. Three brash young medical men. -
<I>Craterellus Excelsus</I>
MYCOTAXON Volume 107, pp. 201–208 January–March 2009 Craterellus excelsus sp. nov. from Guyana Terry W. Henkel1*, M. Catherine Aime2 & Heather K. Mehl1 1Department of Biological Sciences, Humboldt State University Arcata, CA 95521, USA. 2Department of Plant Pathology and Crop Physiology Louisiana State University Agricultural Center Baton Rouge, LA 70803, USA Abstract — Craterellus excelsus (Cantharellaceae, Cantharellales, Basidiomycota) is described from the Pakaraima Mountains of Guyana, where it occurs in rain forests dominated by ectomycorrhizal Dicymbe spp. (Caesalpiniaceae). Craterellus excelsus is noteworthy for its tall (up to 150 mm), persistent, abundant basidiomata that develop in large caespitose clusters. Macromorphological, micromorphological, and habitat data are provided for the new species. Keywords — monodominant forest, tropical fungi, taxonomy, Guiana Shield Introduction In the primary rain forests of Guyana’s Pakaraima Mountains, species of Craterellus and Cantharellus (Cantharellaceae, Cantharellales, Basidiomycota) are conspicuous components of the macromycota associated with ectomycorrhizal (EM) canopy trees of the genus Dicymbe (Caesalpiniaceae, tribe Amherstieae) (Henkel et al. 2002, 2004). Taxa from the Cantharellales occurring in these forests include Cantharellus guyanensis, C. atratus, C. pleurotoides, three undescribed species of Craterellus, and >15 Clavulina species, a number of which remain undescribed (Thacker & Henkel 2004, Henkel et al. 2005, 2006). Here we describe Craterellus excelsus as a distinct new species based on its grey- brown, persistent basidiomata that are regularly >100 mm tall and occur in large caespitose clusters, and its long basidia of variable lengths (75−101 μm) with varying numbers of sterigmata (2−6). Materials and methods Collections were made during the May–July rainy seasons of 2000–2004 from the Upper Potaro River Basin, within a 5 km radius of a permanent base camp *Corresponding author E-mail: [email protected] 202 .. -
Systematics of Division Basidiomycota 2
References: Kirk PM, Cannon PF, Minter DW, Stalpers JA. 2008. Dictionary of the Fungi (10th ed.).Wallingford, UK: CABI. Webster, J., & Weber, R. (2007). Introduction to fungi. Cambridge, UK: Cambridge University Press. SYSTEMATICS OF DIVISION BASIDIOMYCOTA 2 THELEPHOROID CLADE This includes the order Thelephorales, a small group of predominantly ectomycorrhizal fungi with variable basidiocarps. The most important genus is Thelephora. T. terrestris produces clusters of fanshaped basidiocarps which are chocolate-brown in colour with a paler margin. They are often formed around the stem of young trees, seemingly ‘choking’ them. Basidiocarps of T. terrestris superficially resemble those of Stereum but are monomitic, composed of clamped generative hyphae only. The basidiospores are brown and warty. Thelephora terrestris fruits in association with coniferous trees growing on light sandy soils and heaths. It isone of a group of early-stage ectomycorrhizal associates of a variety of trees and also forms mycorrhiza with Arbutus menziesii, a member of the Ericaceae (Webster& Weber, 2007). HYMENOCHAETOID CLADE One feature that distinguishes the five Homobasidiomycete clades considered in the previous sections from the remaining three clades is the structure of the parenthesome, i.e. the membranous structure overarching the septal pore. In the five clades already described, the typical homobasidiomycete dolipore with a perforated parenthesome is found, whereas in the hymenochaetoid, cantharelloid and gomphoid_phalloid clades shown in, the parenthesome is generally imperforate. Imperforate parenthesomes are also found in certain Heterobasidiomycetes, namely Dacrymycetales and Auriculariales. The hymenochaetoid clade comprises about 630 species recruited from three families, namely the entire Hymenochaetaceae and parts of Corticiaceae and Polyporaceae (Webster& Weber, 2007). -
FICE Code List for Colleges and Universities (X0011)
FICE Code List For Colleges And Universities ALABAMA ALASKA 001002 ALABAMA A & M 001061 ALASKA PACIFIC UNIVERSITY 001005 ALABAMA STATE UNIVERSITY 066659 PRINCE WILLIAM SOUND C.C. 001008 ATHENS STATE UNIVERSITY 011462 U OF ALASKA ANCHORAGE 008310 AUBURN U-MONTGOMERY 001063 U OF ALASKA FAIRBANKS 001009 AUBURN UNIVERSITY MAIN 001065 UNIV OF ALASKA SOUTHEAST 005733 BEVILL STATE C.C. 001012 BIRMINGHAM SOUTHERN COLL ARIZONA 001030 BISHOP STATE COMM COLLEGE 001081 ARIZONA STATE UNIV MAIN 001013 CALHOUN COMMUNITY COLLEGE 066935 ARIZONA STATE UNIV WEST 001007 CENTRAL ALABAMA COMM COLL 001071 ARIZONA WESTERN COLLEGE 002602 CHATTAHOOCHEE VALLEY 001072 COCHISE COLLEGE 012182 CHATTAHOOCHEE VALLEY 031004 COCONINO COUNTY COMM COLL 012308 COMM COLLEGE OF THE A.F. 008322 DEVRY UNIVERSITY 001015 ENTERPRISE STATE JR COLL 008246 DINE COLLEGE 001003 FAULKNER UNIVERSITY 008303 GATEWAY COMMUNITY COLLEGE 005699 G.WALLACE ST CC-SELMA 001076 GLENDALE COMMUNITY COLL 001017 GADSDEN STATE COMM COLL 001074 GRAND CANYON UNIVERSITY 001019 HUNTINGDON COLLEGE 001077 MESA COMMUNITY COLLEGE 001020 JACKSONVILLE STATE UNIV 011864 MOHAVE COMMUNITY COLLEGE 001021 JEFFERSON DAVIS COMM COLL 001082 NORTHERN ARIZONA UNIV 001022 JEFFERSON STATE COMM COLL 011862 NORTHLAND PIONEER COLLEGE 001023 JUDSON COLLEGE 026236 PARADISE VALLEY COMM COLL 001059 LAWSON STATE COMM COLLEGE 001078 PHOENIX COLLEGE 001026 MARION MILITARY INSTITUTE 007266 PIMA COUNTY COMMUNITY COL 001028 MILES COLLEGE 020653 PRESCOTT COLLEGE 001031 NORTHEAST ALABAMA COMM CO 021775 RIO SALADO COMMUNITY COLL 005697 NORTHWEST -
9B Taxonomy to Genus
Fungus and Lichen Genera in the NEMF Database Taxonomic hierarchy: phyllum > class (-etes) > order (-ales) > family (-ceae) > genus. Total number of genera in the database: 526 Anamorphic fungi (see p. 4), which are disseminated by propagules not formed from cells where meiosis has occurred, are presently not grouped by class, order, etc. Most propagules can be referred to as "conidia," but some are derived from unspecialized vegetative mycelium. A significant number are correlated with fungal states that produce spores derived from cells where meiosis has, or is assumed to have, occurred. These are, where known, members of the ascomycetes or basidiomycetes. However, in many cases, they are still undescribed, unrecognized or poorly known. (Explanation paraphrased from "Dictionary of the Fungi, 9th Edition.") Principal authority for this taxonomy is the Dictionary of the Fungi and its online database, www.indexfungorum.org. For lichens, see Lecanoromycetes on p. 3. Basidiomycota Aegerita Poria Macrolepiota Grandinia Poronidulus Melanophyllum Agaricomycetes Hyphoderma Postia Amanitaceae Cantharellales Meripilaceae Pycnoporellus Amanita Cantharellaceae Abortiporus Skeletocutis Bolbitiaceae Cantharellus Antrodia Trichaptum Agrocybe Craterellus Grifola Tyromyces Bolbitius Clavulinaceae Meripilus Sistotremataceae Conocybe Clavulina Physisporinus Trechispora Hebeloma Hydnaceae Meruliaceae Sparassidaceae Panaeolina Hydnum Climacodon Sparassis Clavariaceae Polyporales Gloeoporus Steccherinaceae Clavaria Albatrellaceae Hyphodermopsis Antrodiella -
Chemical Elements in Ascomycetes and Basidiomycetes
Chemical elements in Ascomycetes and Basidiomycetes The reference mushrooms as instruments for investigating bioindication and biodiversity Roberto Cenci, Luigi Cocchi, Orlando Petrini, Fabrizio Sena, Carmine Siniscalco, Luciano Vescovi Editors: R. M. Cenci and F. Sena EUR 24415 EN 2011 1 The mission of the JRC-IES is to provide scientific-technical support to the European Union’s policies for the protection and sustainable development of the European and global environment. European Commission Joint Research Centre Institute for Environment and Sustainability Via E.Fermi, 2749 I-21027 Ispra (VA) Italy Legal Notice Neither the European Commission nor any person acting on behalf of the Commission is responsible for the use which might be made of this publication. Europe Direct is a service to help you find answers to your questions about the European Union Freephone number (*): 00 800 6 7 8 9 10 11 (*) Certain mobile telephone operators do not allow access to 00 800 numbers or these calls may be billed. A great deal of additional information on the European Union is available on the Internet. It can be accessed through the Europa server http://europa.eu/ JRC Catalogue number: LB-NA-24415-EN-C Editors: R. M. Cenci and F. Sena JRC65050 EUR 24415 EN ISBN 978-92-79-20395-4 ISSN 1018-5593 doi:10.2788/22228 Luxembourg: Publications Office of the European Union Translation: Dr. Luca Umidi © European Union, 2011 Reproduction is authorised provided the source is acknowledged Printed in Italy 2 Attached to this document is a CD containing: • A PDF copy of this document • Information regarding the soil and mushroom sampling site locations • Analytical data (ca, 300,000) on total samples of soils and mushrooms analysed (ca, 10,000) • The descriptive statistics for all genera and species analysed • Maps showing the distribution of concentrations of inorganic elements in mushrooms • Maps showing the distribution of concentrations of inorganic elements in soils 3 Contact information: Address: Roberto M. -
Atlantic Cape Community College 2019-2020 Catalog
SEE WHERE ATLANTIC CAPE CAN TAKE YOU. 2019-2020 CATALOG ACADEMIC CALENDAR Fall 2019 Spring 2020 Labor Day, College closed ......................................................September 2 Martin Luther King, Jr. Day, College closed ................................January 20 Fall Classes begin, Full Semester (ML & AC) ..............September 3 Spring Classes begin, Full Semester (ML & AC) ............ January 21 Last day to drop with 100% refund in person ........................... August 30 Last day to drop with 100% refund in person .......................January 17 Last day to drop with 100% refund, online, mail or fax* ....September 2 Last day to drop with 100% refund, online, mail or fax* ...January 20 Drop/Add .......................................................................September 3-9 Drop/Add ................................................................... January 21-27 Last day to drop with 50% refund ...................................September 16 Last day to drop with 50% refund .................................... February 3 Last day to drop with Withdraw grade ...............................November 8 Last day to drop with Withdraw grade ............................... March 27 First 8-week Fall Session .............................. September 3-Oct. 26 Cape May Spring Session, 12 weeks .............. January 21-April 18 Last day to drop with 100% refund in person ....................... August 30 Last day to drop with 100% refund in person .......................January 17 Last day to drop with 100% refund, online, -
Re-Thinking the Classification of Corticioid Fungi
mycological research 111 (2007) 1040–1063 journal homepage: www.elsevier.com/locate/mycres Re-thinking the classification of corticioid fungi Karl-Henrik LARSSON Go¨teborg University, Department of Plant and Environmental Sciences, Box 461, SE 405 30 Go¨teborg, Sweden article info abstract Article history: Corticioid fungi are basidiomycetes with effused basidiomata, a smooth, merulioid or Received 30 November 2005 hydnoid hymenophore, and holobasidia. These fungi used to be classified as a single Received in revised form family, Corticiaceae, but molecular phylogenetic analyses have shown that corticioid fungi 29 June 2007 are distributed among all major clades within Agaricomycetes. There is a relative consensus Accepted 7 August 2007 concerning the higher order classification of basidiomycetes down to order. This paper Published online 16 August 2007 presents a phylogenetic classification for corticioid fungi at the family level. Fifty putative Corresponding Editor: families were identified from published phylogenies and preliminary analyses of unpub- Scott LaGreca lished sequence data. A dataset with 178 terminal taxa was compiled and subjected to phy- logenetic analyses using MP and Bayesian inference. From the analyses, 41 strongly Keywords: supported and three unsupported clades were identified. These clades are treated as fam- Agaricomycetes ilies in a Linnean hierarchical classification and each family is briefly described. Three ad- Basidiomycota ditional families not covered by the phylogenetic analyses are also included in the Molecular systematics classification. All accepted corticioid genera are either referred to one of the families or Phylogeny listed as incertae sedis. Taxonomy ª 2007 The British Mycological Society. Published by Elsevier Ltd. All rights reserved. Introduction develop a downward-facing basidioma. -
<I>Rhomboidia Wuliangshanensis</I> Gen. & Sp. Nov. from Southwestern
MYCOTAXON ISSN (print) 0093-4666 (online) 2154-8889 Mycotaxon, Ltd. ©2019 October–December 2019—Volume 134, pp. 649–662 https://doi.org/10.5248/134.649 Rhomboidia wuliangshanensis gen. & sp. nov. from southwestern China Tai-Min Xu1,2, Xiang-Fu Liu3, Yu-Hui Chen2, Chang-Lin Zhao1,3* 1 Yunnan Provincial Innovation Team on Kapok Fiber Industrial Plantation; 2 College of Life Sciences; 3 College of Biodiversity Conservation: Southwest Forestry University, Kunming 650224, P.R. China * Correspondence to: [email protected] Abstract—A new, white-rot, poroid, wood-inhabiting fungal genus, Rhomboidia, typified by R. wuliangshanensis, is proposed based on morphological and molecular evidence. Collected from subtropical Yunnan Province in southwest China, Rhomboidia is characterized by annual, stipitate basidiomes with rhomboid pileus, a monomitic hyphal system with thick-walled generative hyphae bearing clamp connections, and broadly ellipsoid basidiospores with thin, hyaline, smooth walls. Phylogenetic analyses of ITS and LSU nuclear RNA gene regions showed that Rhomboidia is in Steccherinaceae and formed as distinct, monophyletic lineage within a subclade that includes Nigroporus, Trullella, and Flabellophora. Key words—Polyporales, residual polyporoid clade, taxonomy, wood-rotting fungi Introduction Polyporales Gäum. is one of the most intensively studied groups of fungi with many species of interest to fungal ecologists and applied scientists (Justo & al. 2017). Species of wood-inhabiting fungi in Polyporales are important as saprobes and pathogens in forest ecosystems and in their application in biomedical engineering and biodegradation systems (Dai & al. 2009, Levin & al. 2016). With roughly 1800 described species, Polyporales comprise about 1.5% of all known species of Fungi (Kirk & al. -
Curriculum Vitae: James R. Andrews, M.D. 1
Curriculum Vitae: James R. Andrews, M.D. James R. Andrews, M.D. Curriculum Vitae EDUCATION Fellowships Knee Surgery & Athletic Injuries July 1972 - December 1972 University of De Lyon, France Service De Professor: Albert Trillat, M.D Hand Surgery & Athletic Medicine January 1972 - June 1972 University of Virginia Medical Center Sponsor: Frank C. McCue, III, M.D. Chief of Service: Warren Stamp, M.D. Residency Tulane University School of Medicine July 1, 1968-December 30, 1972 Department of Orthopedic Surgery Chief of Service: Jack Wickstrom, M.D Third Year Residency Rotation, Columbus, GA July 1970-July 1971 With: Jack C. Hughston, MD Post-Graduate Tulane Basic Science Course Jan. 1970 - June 1970 Internship USPHS Hospital July 1967-June 1968 San Francisco, CA Mixed Medicine Medical School Louisiana State University School of Medicine 1963-1967 New Orleans, Louisiana Externship University of Washington Summer 1964 Three Months – Orthopaedics and Physical Medicine Louisiana State University 1960-1963 Baton Rouge, Louisiana Bachelor of Science Degree Homer School System ( Grades: 1-12) 1948-1960 Homer, Louisiana 1 Curriculum Vitae: James R. Andrews, M.D. PRIVATE PRACTICE The Andrews Institute Part-time: May 2005 – April 2011 Gulf Breeze, FL Full-time: April 2011 – Present Andrews Sports Medicine & Orthopaedic Center November 2007 – April 2011 Birmingham, AL Alabama Sports Medicine & Orthopaedic Center October 1986 – November 2007 Birmingham, AL (name changed) Hughston Orthopaedic Clinic January 1973-October 1986 Columbus, GA RESEARCH AND EDUCATIONAL ACTIVITIES Medical Director of the Andrews Institute May 2005-Present President & Chairman of the Board: Andrews Research & Education May 2005 – Present Foundation (formally Andrews Research & Education Institute) Chairman of the Board & Medical Director: American Sports Medicine October 1986 - Present Institute (ASMI) AREAS OF SPECIAL INTEREST & CONCERN: 1.