From: [email protected] on behalf of Lindo, Allisa Subject: Mount Sinai In The News - March 31, 2015 Date: Tuesday, March 31, 2015 11:10:05 AM Attachments: ATT00001.txt

In the News March 31, 2015

WBBM Newsradio – March 30 New Device for Lowering Stroke Risk – Kris Van Cleave Eighty year old Margaret is minutes away from getting a new device that will lower her risk of stroke. She has atrial fibrillation which can throw the heart out of rhythm, putting her at greater risk for a stroke. Her doctor recommended she try a new FDA approved device called the WATCHMAN. Surgeons at The Mount Sinai Hospital implanted the parachute shaped device through a vein in the leg, closing off an area of the heart where blood clots form. The Mount Sinai Hospital’s Vivek Reddy, MD, thinks it’s better than medications, especially for the elderly. “Elderly patients, when they have risk for falling, of course they could hurt themselves particularly badly if they are on blood thinners,” says Reddy. - Dr. Vivek Reddy, Professor, Medicine, Cardiology, Icahn School of Medicine at Mount Sinai, Director, Arrhythmia Services, Mount Sinai Health System Learn more: No Web Link Available

Newsweek – March 30 Pesticides on Vegetables and Fruit Linked to Lower Sperm Counts – Douglas Main Fruit and vegetables are good for you, but the pesticide residues that can linger upon them carry a number of health risks. For the first time, scientists have shown that men who eat produce with a lot of chemical residues may be less fertile. “The paper makes a convincing case that dietary exposure to pesticides can adversely impact semen quality,” write researchers Hagai Levine and Shanna Swan, PhD, who weren’t involved in the study, in a commentary in Human Reproduction. “While this finding will need to be replicated in other settings and populations, it carries important public health implications,” add Levine and Swan, who are at Hebrew University in Jerusalem and the Icahn School of Medicine at Mount Sinai Hospital in New York, respectively. -Shanna Swan, PhD, Professor, Preventative Medicine, Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai Learn more: http://www.newsweek.com/pesticides-vegetables-and-fruit-linked-lower-sperm-counts- 318164

HealthDay – March 30 Breast Cancer Is Not One Disease, Experts Say – Robert Preidt Breast cancer isn't the same for every woman, even at the cellular level, according to a new statement from four major medical groups focused on the disease. The report was issued Monday by the American Cancer Society, the U.S. Centers for Disease Control and Prevention, the U.S. National Cancer Institute, and the North American Association of Central Cancer Registries. They say that classifying breast cancers according to tumor subtypes could help improve treatment of the disease. Charles Shapiro, MD, is director of Translational Breast Cancer Research at the Tisch Cancer Institute at Mount Sinai in New York City. He agreed that "the biology of these subtypes is of critical importance to selecting the most effective treatments for breast cancer.” “What was less clear was the apparent influence of race and ethnicity across these subtypes," he added. "That is of great importance to understand why these differences do exist and the biology that underlies them." - Dr. Charles Shapiro, Senior Faculty, Medicine, Thrombosis, Icahn School of Medicine at Mount Sinai, Co-Director, Dubin Breast Center at the Mount Sinai Hospital Learn more: http://consumer.healthday.com/cancer-information-5/breast-cancer-news-94/breast-cancer- is-not-one-disease-experts-say-697818.html Additional Coverage: U.S. News & World Report: http://health.usnews.com/health-news/articles/2015/03/30/breast-cancer-is- not-one-disease-experts-say

BioPharm Insight – March 27 Gildead Harvoni Sees Mixed Reimbursement Practices for Patients Eligible for Eight Weeks of Treatment Gilead Sciences’ hepatitis C pill Harvoni (sofosbuvir/ sofosbuvir) has seen inconsistent reimbursement policies for patients eligible for eight weeks, rather than the standard 12 weeks, of treatment, experts said. There is a caveat for eight weeks of treatment for some patients on the drug’s label, and experts cited this language as the primary reason for differing reimbursement policies. From a financial perspective, the cost of retreating a few relapsed patients does not outweigh the savings from insisting on eight weeks for all qualifying patients, said the expert. However, from a patient perspective, it makes sense that clinicians would want to pursue the safer, 12-week route, the expert continued. Sometimes it is possible to make an appeal to the payer’s medical director, but this strategy is not always successful, said Douglas Dieterich, MD, professor, Medicine, Division of Liver Disease, Icahn School of Medicine at Mount Sinai, New York. - Dr. Douglas Dieterich, Professor, Medicine, Liver Diseases, Icahn School of Medicine at Mount Sinai Learn more: No Web Link Available

Fit Pregnancy – March 30 How Millennials Do Pregnancy Differently – Andrea Stanley There’s no shortage of stereotypical parenting styles that yo-yo from the super involved to the hands- off. Now there’s a new mom on the block—the millennial. Her pregnancy must-have? A smartphone. According to a study conducted by Weber Shandwick, a public relations firm, millennial moms are spending more time online than any other generation. “I think the Internet is a great tool for pregnant women to get information,” says Joanne Stone, MD, director of maternal fetal medicine at The Mount Sinai Hospital. “It’s helping them become more informed and more involved. They can get information about their doctors, pregnancy conditions and find good educational material. For example, if a patient is diagnosed with a problem, there are online support groups they can join.” There’s one giant rule Stone urges expecting mamas to remember: “Some sources are more trustworthy than others, so you should always run questions and problems by your doctor, as well,” she says. - Dr. Joanne Stone, Professor, Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai, Director, Maternal Fetal Medicine, The Mount Sinai Hospital Learn more: http://www.fitpregnancy.com/pregnancy/how-millennials-do-pregnancy-differently

Buzzfeed – March 29 22 Things You Should Know About Your Behind – Carolyn Kylstra IBS, or irritable bowel syndrome, affects about twice as many women as it does men, according to the National Institutes of Health. In order for you to be diagnosed with IBS, doctors have to rule out a bunch of other things first, says Gina Sam, MD, MPH, director of the Mount Sinai Gastrointestinal Motility Center. For starters, your doctor should rule out celiac disease (an auto-immune disorder where eating gluten causes damage to your small intestine). Once that’s ruled out, “you have to have no blood in your stool, no alarming symptoms, like anemia, and your symptoms have to be going on for more than three months,” Sam says. Basically, the symptoms need to be ongoing, chronic, and not caused by other things. “Also, the pain has to go away after a bowel movement,” she says. - Dr. Gina Sam, Assistant Professor, Medicine, Gastroenterology, Icahn School of Medicine at Mount Sinai, Director, Mount Sinai Gastrointestinal Motility Center at the Mount Sinai Hospital Learn more: http://www.buzzfeed.com/carolynkylstra/no-butts-about-it

Buzzfeed – March 25 9 Reasons You Can’t Poop – Carolyn Kylstra About a third of people who have constipation are dealing with “low-fiber constipation,” Gina Sam, MD, MPH, Director of the Mount Sinai Gastrointestinal Motility Center, tells BuzzFeed Life. Start eating four to five servings of fruits and vegetables a day and see if that gets things moving again. “You basically need water in order for your stool to move through the colon,” Sam says. When you don’t drink enough water, that can back you up. If you’re dealing with constipation, Sam says you should try to drink eight to ten glasses of water a day, and see if that helps a bit. - Dr. Gina Sam, Assistant Professor, Medicine, Gastroenterology, Icahn School of Medicine at Mount Sinai, Director, Mount Sinai Gastrointestinal Motility Center at the Mount Sinai Hospital Learn more: http://www.buzzfeed.com/carolynkylstra/constipation-station

Daily Burn – March 30 Deep Freeze: Could Cryotherapy Replace Ice Baths for Athletes? – Amanda Woerner Would you believe that exposing your body temperatures of negative 182 to 292 degrees Fahrenheit is actually more enjoyable than getting hit with a blast of freezing wind on an icy day? To test the frigid fad, I stood in a freezing cold chamber for nearly three minutes. While I felt refreshed after my one-time cryo treatment, the benefits of a practicing cryotherapy long-term are still murky. Johnny Arnouk, MD, sports medicine specialist and orthopedic surgeon at Mount Sinai Beth Israel in New York City, says there’s still a lot of research to be done. “There needs to be better data to better delineate the risks and benefits of [whole body cryotherapy],” he says. “Parameters for length of time exposed and conditions need to be better marked out as well.” - Dr. Johnny Arnouk, Sports Medicine Specialist, Orthopaedist, Mount Sinai Beth Israel Learn more: http://dailyburn.com/life/fitness/what-is-cryotherapy/

The Huffington Post via Reuters – March 30 Moms' Excess Pregnancy Weight Linked To Kids' Obesity – Madeline Kennedy Mothers who are overweight before pregnancy and those who gain too much while pregnant are more likely to have obese seven-year-olds, researchers say. Their study, conducted from 1998 to 2013, focused on African-American and Dominican mothers from low-income neighborhoods in New York City. Andrea Deierlein of the Icahn School of Medicine at Mount Sinai Hospital noted in an email that there are “many risks associated with childhood obesity - obese children are more likely to be obese throughout adolescence and adulthood.” Deierlein, who was not involved in the study, noted that in adulthood, the risks associated with obesity include type 2 diabetes, hypertension and sleep disturbances. Past research has also shown that overweight mothers are more likely to give birth to larger than normal babies, and those babies are at high risk of growing up to be obese. - Andrea Deierlin, PhD, Postdoctoral Fellow, Preventive Medicine, Icahn School of Medicine at Mount Sinai Learn more: http://www.huffingtonpost.com/2015/03/30/mom-pregnancy-weight-childhood- obesity_n_6972736.html

Fusion – March 30 I Survived Blindfolded Speed Dating – Isha Aran Getting to know people is hard enough, but getting to know people while blindfolded? It’s easier than you might think. Welcome to Sensory Speed Dating. A few weeks ago, I put on something nice and braved the New York City cold to attend an event that promised to turn attraction into a science. It was hosted by Guerilla Science, a group dedicated to “revolutionizing” how people experience science by making it accessible. Our yenta for the evening was Heather Berlin, PhD, a professor of psychiatry and neuroscience at Icahn School of Medicine at Mount Sinai and host of Discovery Channel’s Superhuman Showdown. “We think we’re the masters of our own destiny and decisions, but there are a lot of things at play,” Berlin told Fusion, referring to the neurochemical processes that happen in the brain when we spend time with people. “The brain is dictating behavior.” -Heather Berlin, PhD, Assistant Professor of Neuroscience and Psychiatry, Icahn School of Medicine at Mount Sinai Learn more: http://fusion.net/story/104602/i-survived-guerilla-science-sensory-speed-dating/

New York Post – March 30 Baby Born In Back of Uber on Way to Hospital – Rebecca Harshbarger and Sophia Rosenbaum A pregnant Brooklyn mom woke up to contractions Monday morning and hopped into an Uber car to head to hospital — only to wind up giving birth in the back seat. “We heard crying. The next thing I know, I had a baby in my hand. We were all in shock,” dad David Horvitz, 33, told The Post. Horvitz digitally hailed the Nissan Altima with the Uber app for his wife, Zanna Gilbert, a 34-year-old art historian and curator at the MOMA, after she woke up around 5 a.m. The couple told Uber driver Germaine Allen, 32, to take them to their Manhattan hospital, The Mount Sinai Hospital, about 12 miles away. They got as far as 57th Street and Park Avenue, a couple blocks from Mount Sinai, when their 7- pound daughter was born. Allen drove on to the hospital, and nurses rushed out to help the couple. - The Mount Sinai Hospital Learn more: http://nypost.com/2015/03/30/baby-born-in-back-of-uber-on-way-to-hospital/

AustrianTribune.com – March 30 After Double Mastectomy, Angelina Jolie Gets Her Ovaries And Fallopian Tubes Removed – Helena Rudhart Last week, Angelina Jolie underwent a laparoscopic bilateral salpingo-oophorectomy in order to remove her ovaries and fallopian tubes. The news has led to discussion on social media. In fact, as per doctors, the news will encourage many women to consider undergoing genetic testing. Studies have shown that elective surgeries can significantly reduce the risk of cancer. David Fishman, MD, Director of the Mount Sinai Ovarian Cancer Risk Assessment Program in New York City, said, "A Nobel laureate could give the same message, and it might reach only a handful of people. Angelina is using her celebrity in a heroic way, and she's going to reach millions of people worldwide". - Dr. David Fishman, Professor, Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai, Director, Mount Sinai Ovarian Cancer Risk Assessment Program, The Mount Sinai Hospital Learn more: http://austriantribune.com/informationen/155063-after-double-mastectomy-angelina-jolie- gets-removed-her-ovaries-and-fallopian

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: [email protected] on behalf of Lindo, Allisa Subject: Mount Sinai In The News - March 30, 2015 Date: Monday, March 30, 2015 11:31:21 AM Attachments: ATT00001.txt

In the News March 30, 2015

Endocrine Web – March 27 Artificial Pancreas Is Being Tested for Overnight Use in Type 1 Diabetes An artificial pancreas system that uses a smart phone application to continuously monitor blood sugar levels and communicate with an insulin pump to give small doses of insulin when needed is currently being tested for use overnight in a clinical trial by researchers at the Icahn School of Medicine at Mount Sinai, New York, NY. “The study was done at night based on the belief that the biggest challenge that people with type 1 diabetes have with glucose management is when they can’t focus on it and make their own adjustments,” said lead investigator Carol Levy, MD, Associate Professor of Medicine, Endocrinology, Diabetes and Bone Disease at the Icahn School of Medicine at Mount Sinai. - Dr. Carol Levy, Associate Professor, Medicine, Endocrinology, Diabetes and Bone Disease, Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai Learn more: http://www.endocrineweb.com/news/type-1-diabetes/14134-artificial-pancreas-being- tested-overnight-use-type-1-diabetes

The Johns Hopkins Newsletter – March 26 A Sense of Purpose Can Help You Live a Longer Life – Sunny Cai A new study by researchers at the Mount Sinai St. Luke’s Hospital and the Mount Sinai Roosevelt Hospital demonstrates that people with a high sense of purpose in their lives, who have high ikigai, may have a reduced risk of dying from cardiovascular events, such as heart disease and stroke. The researchers performed a meta-analysis of relevant studies in order to assess the impact of ikigai on cardiovascular events and mortality. Randy Cohen, MD, Chirag Bavishi, MD, and Alan Rozanski, MD, led the meta-analysis study. - Dr. Randy Cohen, Medical Director, University Medical Practice Associates, Mount Sinai St. Luke’s, Mount Sinai Roosevelt - Dr. Alan Rozanski, Professor, Medicine, Cardiology, Icahn School of Medicine at Mount Sinai, Director, Wellness and Prevention Programs, The Mount Sinai Hospital - Dr. Chirag Bavishi, PGY3, Mount Sinai St. Luke’s, Mount Sinai Roosevelt Learn more: http://www.jhunewsletter.com/2015/03/26/a-sense-of-purpose-can-help-you-live-a-longer- life-11740/

Healio – March 29 Jagat Narula, MD, Receives ACC Distinguished Scientist Award The American College of Cardiology presented Jagat Narula, MD, PhD, MACC, associate dean for global affairs at Icahn School of Medicine at Mount Sinai and Cardiology Today Editorial Board member, with its Distinguished Scientist Award at the ACC Annual Scientific Sessions in San Diego. Narula received the award in recognition of his contributions to translational medicine in CVD, according to a press release. “This award is one of my most treasured honors of my career,” Narula said in the release. “I am grateful to the American College of Cardiology for this prestigious recognition of my scientific pursuits to advance cardiac patient care, research and medical education.” - Dr. Jagat Narula, Professor, Medicine, Cardiology, Radiology, Associate Dean for Global Affairs, Icahn School of Medicine at Mount Sinai, Chief, Cardiology, Mount Sinai St. Luke’s, Mount Sinai Roosevelt, Director, Cardiovascular Imaging, Mount Sinai Health System Learn more: http://www.healio.com/cardiology/practice-management/news/online/%7B2329d5ab-7fb1- 4f97-8103-305a110f19c1%7D/jagat-narula-md-receives-acc-distinguished-scientist-award

Time – March 26 Dealing with the Allergy Crisis – Kristina Dell No one knows for sure what’s behind the dramatic escalation in food allergies. Scientists believe environment and epigenetics —how the environment alters genetic inheritance—must be at work. In the U.S. alone, the prevalence of peanut allergies went from one in 250 kids to one in 70 kids from 1997 to 2008, according to a survey done by Hugh Sampson, MD, and Scott Sicherer, MD, of the Jaffe Food Allergy Institute at The Mount Sinai Hospital in New York City. “It’s so short of a time frame,” says Sicherer. “It has to be that something about the environment has changed.” - Dr. Hugh Sampson, Professor, Pediatrics, Allergy and Immunology, Dean, Translational Biomedical Research, Icahn School of Medicine at Mount Sinai - Dr. Scott Sicherer, Elliot and Roslyn Jaffe Professorship in Pediatric Allergy and Immunology, Icahn School of Medicine at Mount Sinai Learn more: http://time.com/the-allergy-crisis/ [Login Required]

Newsweek – March 26 Iceland Completes DNA Records for Entire Nation – Hayley Richardson Researchers in Iceland have recorded the human genetic code of the “entire nation” in the largest ever study of its kind. It means it is now technically possible to identify every woman at high risk of breast cancer in the country. Jason Bobe, executive director of Personal Genomes (a project dedicated to creating public genome, health, and trait data) and director of the Sharing Lab at the Icahn Institute at Mount Sinai, says the project is an “impressive effort”. “It is clear that sequencing the DNA of entire populations will increasingly be the easy part,” he says. “The real challenges ahead will be engaging people and their healthcare providers with this information in ways that improve health.” - Jason Bobe, PhD, Senior Faculty, Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, Director, The Sharing Lab at the Icahn Institute at Mount Sinai Learn more: http://www.newsweek.com/iceland-completes-dna-records-entire-nation-317007

The Huffington Post – March 27 What Is Palliative Care, Anyway? – Diane Meier, MD Palliative care is a new medical specialty that focuses on improving the quality of life of seriously ill patients and their families by addressing the pain, symptoms, and stress caused by serious illness. It is delivered by a team of doctors, nurses, social workers, and others, who work alongside patients' regular doctors to provide an added layer of support. The short answer is that all hospice is palliative care, but not all palliative care is hospice. - Dr. Diane Meier, Professor, Geriatrics and Palliative Medicine, Medicine, Icahn School of Medicine at Mount Sinai Learn more: http://www.huffingtonpost.com/mount-sinai-health-system/palliative-care_b_6925216.html

NPR All Things Considered – March 26 New York City’s First Lady Discusses Mental Health Mental health is often an overlooked part of the health system. Seated on a stage in front of a crowd of about three hundred people, the First Lady of New York City, Chirlane McCray said she had a hard time maneuvering through the mental health system to find help for her daughter. “It wasn’t easy to find the services that she needed,” says McCray. She mentioned an adolescent unit at Mount Sinai as an example where she says young people get a physical by a doctor and then get seen by a social worker too. - Mount Sinai Adolescent Health Center Learn more: No Web Link Available

Yahoo Health – March 30 9 Foods That Up Your Kidney Stone Risk (Including Kale!) – Ashley Macha The health nut community has eagerly jumped on the kale bandwagon over the past few years, and it doesn’t show signs of stopping. But could this superfood be doing more harm than good? While kale is loaded with vitamins C, K, and A, it also touts high levels of oxalate, a naturally produced compound found in many common foods. Consumption of too many foods high in oxalate can increase the amount of oxalate in the urine, which bonds with calcium in the urine to form little build-ups called calcium- oxalate kidney stones. “I don’t know if I can specifically link it [kidney stones] to kale, but a lot more seemingly healthy people are coming in with kidney stones than in the past,” Mantu Gupta, MD, director of the Kidney Stone Center at Mount Sinai Hospital, tells Yahoo Health. “Another population we’re seeing a lot are people that are on high-protein diets.” - Dr. Mantu Gupta, Senior Faculty, Urology, Icahn School of Medicine at Mount Sinai, Site Chair, Urology, Mount Sinai Roosevelt, Mount Sinai St. Luke’s, Director, The Kidney Stone Center, The Mount Sinai Hospital, Director, Endourology and Stone Disease, Mount Sinai Health System Learn more: https://www.yahoo.com/health/9-foods-that-up-your-c1427474076601.html

Public Health Minute – March 19 Occupational Lung Diseases – Bill Latimer Occupational lung diseases often lead to substantial or total disability and can be untreatable and lethal, and yet virtually all of those diseases are completely preventable. They are caused by exposure to toxic substances at work. Rafael de la Hoz, MD, sits down with Public Health Minute’s Bill Latimer to discuss these diseases. - Dr. Rafael de la Hoz, Associate Professor, Preventive Medicine, Medicine, General Internal Medicine, Icahn School of Medicine at Mount Sinai Learn more: https://soundcloud.com/publichealthminute/occupational-lung-diseases-dr-raphael-de-la- hoz

Today’s Dietitian – February 2015 What's New in the Dairy-Free Aisle – Juliann Schaeffer Consumer demand for plant-based dairy products is on the rise. With this increased popularity come new food and beverage introductions as the dairy-alternative market scrambles to keep up with and cash in on consumer demand. "Today, there are more dairy-free alternatives available as food companies expand their product lines to provide good-tasting, nutritious options for the growing number of consumers seeking dairy-free foods," says Rachel Neifeld, RD, CDN, CDE, of the Gerald J. Friedman Diabetes Institute at Mount Sinai Beth Israel in New York City. -Rachel Neifeld, RD, CDN, CDE, Gerald J. Friedman Diabetes Institute, Mount Sinai Beth Israel Learn more: http://www.todaysdietitian.com/newarchives/021115p30.shtml

The Star (Malaysia) via Reuters – March 30 Men Who Smoke Have Higher Risk of Losing Bone Density – Lisa Rapaport Male smokers have a greater risk for osteoporosis than other men and even than women smokers, a recent study finds, suggesting that U.S. screening guidelines focused on women might need to be expanded to include men. The U.S. Preventive Services Task Force (USPSTF), a government-backed independent organization that reviews medical evidence, last updated screening guidelines for osteoporosis in 2011. "The evidence in 2011 was insufficient to determine the balance of benefits and harms of screening men for osteoporosis because there were few relevant treatment studies in men," said Albert Siu, MD, a co-vice chair of the task force and a professor of geriatrics at the Icahn School of Medicine at Mount Sinai in New York City. - Dr. Albert Siu, Professor, Population Health and Policy, Medicine, General Internal Medicine, Geriatrics and Palliative Medicine, Icahn School of Medicine at Mount Sinai, Chair, Geriatrics and Palliative Medicine, the Mount Sinai Health System Learn more: http://www.thestar.com.my/Lifestyle/Health/2015/03/30/Men-who-smoke-have-higher- risk-of-osteoporosis/

The Oklahoman – March 27 Oklahoma City Thunder: What exactly is going on with Kevin Durant's foot? – Anthony Slater On Friday afternoon, the Thunder officially ruled Kevin Durant out for the remainder of the season. For the third time in less than six months, Durant will have surgery on his bothersome right foot. After the Jones fracture was discovered in his right foot during training camp, Durant had the original surgery, which knocked him out six weeks, and a screw inserted to help with the healing. Jones fracture surgeries have a success rate of between 92 percent to 95 percent. “It’s a little unusual that this didn’t heal,” Steven B. Weinfeld, MD, a foot and ankle specialist from the Icahn School of Medicine at Mount Sinai, said. “Once you put the screw in, these usually heal reliably.” - Dr. Steven Weinfeld, Associate Professor, Orthopaedics, Foot and Ankle Service, Icahn School of Medicine at Mount Sinai Learn more: http://newsok.com/oklahoma-city-thunder-what-exactly-is-going-on-with-kevin-durants- foot/article/5405304/?page=1

The New York Daily News – March 29 Daily Checkup: Dr. Harry Cho of Mount Sinai Hospital Tells Patients How to Avoid Unnecessary Tests and Treatment – Katie Charles As the director of quality and patient safety for the division of hospital medicine at The Mount Sinai Hospital, Harry Cho, MD, works to ensure that all inpatients receive the most appropriate treatments and to prevent adverse outcomes like hospital infections.. If you’ve spent any time in a hospital recently, you know the dizzying array of tests that patients can be presented with. “The most recent studies are making clear how much excess medical care we use in this county — the cost of overuse, overtesting, and overtreatment is about $750 billion a year in this country,” says Cho. - Dr. Harry Cho, Assistant Professor, Medicine, Hospital Medicine, Icahn School of Medicine at Mount Sinai, Director, Quality and Patient Safety, Division of Hospital Medicine, The Mount Sinai Hospital Learn more: http://www.nydailynews.com/life-style/health/dr-harry-cho-unnecessary-tests-treatments- article-1.2160810

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: [email protected] on behalf of MountSinaiNewsNow Subject: Mount Sinai In The News - March 27, 2015 Date: Friday, March 27, 2015 12:02:30 PM Attachments: ATT00001.txt

In the News March 27, 2015

NY1 – March 26 Investigators Probe Cause of East Village Blast A gas explosion ripped through four buildings and ended up leveling three of them, leaving a total of 19 people injured in a bustling section of the East Village Thursday afternoon. The explosion was reported at around 3:17 p.m. at 7th Street and Second Avenue. Fire crews were on the scene within three minutes. Five of the people injured in the explosion were taken to Mount Sinai Beth Israel with non-life- threatening injuries. - Mount Sinai Beth Israel Learn more: http://www.ny1.com/nyc/all-boroughs/news/2015/03/27/investigators-probe-east-village- blast-and-building-collapses.html Additional Coverage: WABC: http://7online.com/news/firefighters-still-at-east-village-explosion-that-injured-19-/574555/ WCBS: http://newyork.cbslocal.com/2015/03/26/explosion-collapse-reported-at-east-village-building/ WNBC: No web link available. Los Angeles Times: http://www.latimes.com/nation/nationnow/la-na-nn-explosion-building-new-york- city-20150326-htmlstory.html New York Daily News: http://www.nydailynews.com/new-york/explosion-shreds-east-village- restaurant-article-1.2163547 The Lo-Down: http://www.thelodownny.com/leslog/2015/03/morning-update-explosion-and-fire-on- 2nd-avenue.html

Reuters – March 27 Moms' excess pregnancy weight linked to kids' obesity – Madeline Kennedy Mothers who are overweight before pregnancy and those who gain too much while pregnant are more likely to have obese seven-year-olds, researchers say. Their study, conducted from 1998 to 2013, focused on African-American and Dominican mothers from low-income neighborhoods in New York City. Andrea Deierlein of the Icahn School of Medicine at Mount Sinai Hospital noted in an email that there are “many risks associated with childhood obesity - obese children are more likely to be obese throughout adolescence and adulthood.” Deierlein, who was not involved in the study, noted that in adulthood, the risks associated with obesity include type 2 diabetes, hypertension and sleep disturbances. Past research has also shown that overweight mothers are more likely to give birth to larger than normal babies, and those babies are at high risk of growing up to be obese. - Dr. Andrea Deierlin, Postdoctoral Fellow, Preventive Medicine, Icahn School of Medicine at Mount Sinai Learn more: http://www.reuters.com/article/2015/03/27/us-pregnancy-weight-child-obesity- idUSKBN0MN1TA20150327

ABC News – March 26 Indiana Governor Overrides Law to Authorize Needle Exchange Indiana Gov. Mike Pence overrode state law and his own anti-drug policies Thursday to authorize a short-term needle-exchange program designed to help contain HIV infections in a rural county where more than six dozen cases have been reported, all of them tied to intravenous drug use. Pence issued an executive order declaring a public health emergency in Scott County, an economically depressed area about 30 miles north of Louisville, Kentucky, that has seen 79 new infections since December. The county typically sees only about five HIV cases each year, health officials said. Don Des Jarlais, director of research for the chemical dependency institute at Mount Sinai Beth Israel in New York, said the places most vulnerable to infections include rural and suburban communities where a new group of drug users started with prescription painkillers and moved onto injecting heroin. Without drug treatment or syringe-exchange programs, these areas "are ripe for outbreaks, and we should expect more of them unless we really ramp up our HIV-prevention services in those areas," he said. - Dr. Don Des Jarlais, Professor, Psychiatry, Preventive Medicine, Icahn School of Medicine at Mount Sinai, Director of Research, Chemical Dependency Institute, Mount Sinai Beth Israel Learn more: http://abcnews.go.com/US/wireStory/indiana-needle-exchange-program-stem-hiv- outbreak-29921870 Additional Coverage: The Fresno Bee: http://www.fresnobee.com/2015/03/26/4449153/indiana-governor-overrides-law.html

Everyday Health – February 24 7 Diabetes Symptoms You Shouldn’t Ignore – Beth Orenstein Blood sugar that’s consistently out of whack increases your risk of health problems throughout your body, including your heart, blood vessels, eyes, kidneys, and nerves. Resulting complications could lead to disabling, even life-threatening, conditions — and that’s why, if you have type 2 diabetes, practicing good diabetes management and maintaining blood sugar control is a must. Being aware of possible complications and their symptoms is one of the first steps to successfully managing diabetes, says Gerald Bernstein, MD, director of the diabetes management program at Mount Sinai Beth Israel Hospital in New York City. Educating yourself may help you delay or prevent complications from happening. - Dr. Gerald Bernstein, Director, Diabetes Management, The Friedman Diabetes Institute, Mount Sinai Beth Israel Learn more: http://www.everydayhealth.com/custom/type-2-diabetes-live-better-guide/symptoms-you- should-not-ignore/

Allure – March 26 Does Drinkable Sunscreen Actually Work? – Kate Sullivan Foods rich in antioxidants, like leafy greens, do seem to offer some sun protection; and as we reported earlier this year, consuming coffee, the nectar of the gods, also led to a reduced risk of skin cancer in a recent study. But as our logic—and experts—have assured us, such things alone are not enough to protect you. "Some supplements have been shown in clinical trials to minimize the harmful effects UV light has on the skin," says Joshua Zeichner, an assistant professor of dermatology at Mount Sinai Hospital in New York City. "They work by helping to boost the skin's ability to fight off damage and by enhancing antioxidant activity. No supplement, however, should take the place of traditional sun- protection measures, like wearing sunscreen, and exercising sun-protective behaviors, such as seeking shade between peak hours of 10 A.M. to 2 P.M. and wearing sun-protective clothing, hats, and glasses." - Dr. Joshua Zeichner, Assistant Professor, Dermatology, Icahn School of Medicine at Mount Sinai, Director, Cosmetic and Clinical Research in Dermatology, The Mount Sinai Hospital Learn more: http://www.allure.com/beauty-trends/blogs/daily-beauty-reporter/2015/03/drinkable- sunscreen-effectiveness.html

Yahoo! Health – March 27 With ‘Text Neck’ Comes...Turkey Neck – Grace Gold Dermatologists and plastic surgeons around the country are citing an increase in patients looking to address sagging jowls and wrinkled necks, which they say is in part due to the high tech age. While holding and propping devices up to eye level is ideal, there are also other preventative measures you can take to strengthen neck skin’s resistance to repetitive movement. “Topical retinoid and retinol creams stimulate collagen and keep the skin elastic, and formulas with antioxidants fend off potential damage from other aggressors like UV light exposure, pollution and cigarette smoke, which can also lead to premature skin aging,” advises Joshua Zeichner, MD, director of Cosmetic and Clinical Research at Mount Sinai Hospital Department of Dermatology. - Dr. Joshua Zeichner, Assistant Professor, Dermatology, Icahn School of Medicine at Mount Sinai, Director, Cosmetic and Clinical Research in Dermatology, The Mount Sinai Hospital Learn more: https://www.yahoo.com/health/with-text-neck-comes-turkey-neck-114753354102.html

Yahoo! Parenting – March 27 Can a Sonogram Reveal Baby’s Personality? – Jennifer O’Neill Saturday Night Live alum Casey Wilson obviously jokes around a lot. But she wasn’t kidding when she recently told Fit Pregnancy magazine that she believes the sonogram photos of her unborn son show that he’s not going to take after her, personality-wise. “We’ve done a couple …and he seems to always have his hands over his eyes,” says the Marry Me actress, 34, of the little boy she’s expecting in May with TV writer David Caspe. “My husband said, ‘Thank God he doesn’t appear to want the spotlight like his mom!’ He seems very shy, which we’re both kind of relieved about.” Dr. Shari Brasner, an obstetrician at The Mount Sinai Hospital, added: “There isn’t too much room in there, so babies’ hands are often near the face.” Children’s personality traits do develop early on, Isabel Blumberg, also an obstetrician at Mount Sinai in New York City, tells Yahoo Parenting, but there’s no way to discern them in the womb. “They start to exhibit signs soon after they’re born so when doctors are doing sonograms and say things like ‘Aw, she’s being shy,’ as babies cover their faces or genitalia, that’s just us commenting,” she says. “The child’s movements are instinctive, not anything that would reveal personality.” - Shari Brasner, MD, Assistant Clinical Professor, Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai - Isabel Blumberg, MD, Clinical Instructor, Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai Learn more: https://www.yahoo.com/parenting/can-a-sonogram-reveal-babys-personality- 114693437187.html

Healthline – March 26 You Can Have Your Cake and Eat It Too With New National Nutrition Rules – Kristen Fischer Which approach works best? Is listing calories on a menu effective? Should people focus on their sugar, overall calorie, or saturated fat consumption? Or should they try to restrict certain foods? Recent studies have shown that restaurant menus featuring calorie information and other nutritional data don’t necessarily convince people to make smarter food choices. Some data does contend the postings help, although they report the effect is minimal. Dr. Christopher Ochner, a weight loss and nutrition specialist at Mount Sinai Hospital in New York City, said he tailors his approach to showing nutritional data to patients depending on “where they’re at. If they have never looked at a nutrition label before, I will tell them to look at them and to just pay attention to the big things,” he said. - Christopher Ochner, PhD, Assistant Professor, Pediatrics, Adolescent Medicine, Psychiatry, Icahn School of Medicine at Mount Sinai Learn more: http://www.healthline.com/health-news/have-your-cake-and-eat-it-too-with-new- national-nutrition-rules-032615#2

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: [email protected] on behalf of MountSinaiNewsNow Subject: Mount Sinai In The News - March 26, 2015 Date: Thursday, March 26, 2015 12:23:01 PM Attachments: ATT00001.txt

In the News March 26, 2015

BioQuick News – March 26 Isogenic iPSCs Used to Dissect 7q Deletion and Identify Candidate Genes for MDS Blood Cancer Induced pluripotent stem cells (iPSCs), adult cells that have been reprogrammed back to an embryonic stem cell-like state, may better model the genetic contributions to each patient's particular disease. In a process called cellular reprogramming, researchers at the Icahn School of Medicine at Mount Sinai in New York City have taken mature blood cells from patients with myelodysplastic syndrome (MDS) and reprogrammed them back into iPSCs to study the genetic origins of this rare blood cancer. In this study, researchers took cells from patients with blood cancer MDS and turned them into stem cells to study the deletions of one copy of the long arm of human chromosome 7 (7q) that are often associated with this disease. "With this approach, we were able to pinpoint a region on chromosome 7 that is critical and were able to identify candidate genes residing there that may cause this disease," said lead researcher Eirini Papapetrou, M.D., Ph.D., Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai. - Eirini Papapetrou, MD, PhD, Associate Professor, Oncological Sciences, Medicine, Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai Learn more: http://www.bioquicknews.com/node/2468

EBioTrade.com – March 26 Functional Analysis of Chromosome Deletion Associated with Myeloplastic Syndrome "With this approach, we were able to pinpoint a region on chromosome 7 that is critical and were able to identify candidate genes residing there that may cause this disease," said lead researcher Eirini Papapetrou, M.D., Ph.D., Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai. - Eirini Papapetrou, MD, PhD, Associate Professor, Oncological Sciences, Medicine, Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai Learn more: http://www.ebiotrade.com/newsf/2015-3/2015326134631582.htm

Health Canal – March 23 In a study published online March 23 in the prestigious journal Nature Biotechnology, Nimer’s team collaborated with Eirini Papapetrou, M.D., Ph.D., who conducted this work in her lab at the University of Washington and now at the Icahn School of Medicine at Mount Sinai in New York, and with Timothy Graubert, M.D., at Massachusetts General Hospital in Boston, as well as with clinical researchers at Memorial Sloan Kettering Cancer Center in New York, to examine the cells of MDSpatients who have lost or deleted chromosome 7 – a condition called del(7q)-. - Eirini Papapetrou, MD, PhD, Associate Professor, Oncological Sciences, Medicine, Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai Learn more: http://www.healthcanal.com/genetics-birth-defects/61600-sylvester-leader%E2%80%99s- genetic-studies-provide-new-insights-into-bone-marrow-disorders.html

CBS News – March 25 New FDA-approved device lowers stroke risk – Kris Van Cleave Patients with atrial fibrillation are at five times greater risk of stroke, and are more likely to have a serious stroke that can be fatal or cause irreversible neurological damage. Approximately half of all stroke patients with atrial fibrillation will die or be left with significant disability. A new device, called the Watchman, is a catheter-delivered heart implant. It closes around the left atrial appendage of the heart to prevent the migration of blood clots and therefore reduce stroke risk in patients with atrial fibrillation. This site is significant because research has found that more than 90 percent of strokes arise from clots that form in the left atrial appendage. With the device in place, "any clots that would form there can't travel to the brain and cause a stroke," Dr. Vivek Reddy, Professor, Medicine, Cardiology, Icahn School of Medicine at Mount Sinai, Director, Arrhythmia Services, Mount Sinai Health System. - Vivek Reddy, Professor, Medicine, Cardiology, Icahn School of Medicine at Mount Sinai, Director, Arrhythmia Services, Mount Sinai Health System Learn more: http://www.cbsnews.com/news/new-fda-approved-device-lowers-stroke-risk-in-a-fib- patients/

CBS News – March 18 Experimental Alzheimer's drug shows promise More than five million Americans suffer from Alzheimer's disease, and as the Baby Boomer generation ages, the terrible toll of the disease is expected to keep growing. There hasn't been a new drug approved to treat Alzheimer's in a decade, but researchers are working hard to change that. A clinical trial is now underway to test a new drug that shows promise for slowing the relentless progression of memory loss and mental decline in Alzheimer's patients. The drug is called T-817MA and it's designed to protect nerve cells in the brain. "We are absolutely hoping it can prevent cognitive decline, it will prevent the disease from progressing and prevent the clinical changes that happen," said Dr. Amy Aloysi, a specialist in geriatric psychiatry at Mount Sinai Hospital in New York City, one of the hospitals taking part in the trial. -Amy Aloysi, MD, Assistant Professor, Psychiatry, Neurology, Icahn School of Medicine at Mount Sinai Learn more: http://www.cbsnews.com/news/experimental-alzheimers-drug-shows-promise/

HealthDay – March 25 FDA Warns of Cardiac Effect When Heart Drug Mixed With Hepatitis C Meds – Robert PreidtA potentially life-threatening slowing of the heart can occur when the common heart drug amiodarone is taken with new hepatitis C medications, the U.S. Food and Drug Administration warns. The dangerous slowing of the heart -- called symptomatic bradycardia -- can occur when amiodarone is taken with the hepatitis C drugs Harvoni (ledipasvir/sofosbuvir) or Sovaldi (sofosbuvir) and combined with another direct-acting antiviral for the treatment of hepatitis C. "While this is a potentially devastating drug interaction in real life, it is unlikely to be a major issue," said Dr. Douglas Dieterich, a professor of liver diseases at the Icahn School of Medicine at Mount Sinai in New York City. "In fact, I cannot recall treating a hepatitis C patient who was on amiodarone in the last five years," he said. - Douglas Dieterich, MD, Professor, Medicine, Liver Diseases, Icahn School of Medicine at Mount Sinai Learn more: http://consumer.healthday.com/infectious-disease-information-21/hepatitis-news-373/fda- warns-of-cardiac-effect-when-heart-drug-mixed-with-hepatitis-c-meds-697729.html Additional Coverage: WebMD: http://www.webmd.com/hepatitis/news/20150325/fda-warns-of-cardiac-effect-when-heart- drug-mixed-with-hepatitis-c-meds

HealthDay – March 25 Study Ties Frequent Antibiotic Use to Higher Odds for Type 2 Diabetes – Robert Preidt Repeated use of certain antibiotics may increase a person's risk for type 2 diabetes, a new study suggests. Researchers analyzed data from one million people in the United Kingdom and found that those who were prescribed at least two courses of four types of antibiotics -- penicillins, cephalosporins, quinolones and macrolides -- were more likely to develop diabetes. The risk of diabetes rose with the number of antibiotics prescribed, the findings showed. Two to five courses of a penicillin increased the risk of diabetes by 8 percent, while more than five courses increased the risk by 23 percent. "It has been recognized for some time that bacteria in one part of the body can contribute to inflammation in another," said Dr. Gerald Bernstein, director of diabetes management at The Friedman Diabetes Institute, part of Mount Sinai Beth Israel Hospital in New York City. - Gerald Bernstein, MD, Director, Diabetes Management, The Friedman Diabetes Institute, Mount Sinai Beth Israel Learn more: http://consumer.healthday.com/diabetes-information-10/misc-diabetes-news-181/study- ties-frequent-antibiotic-use-to-higher-odds-for-type-2-diabetes-697721.html Additional Coverage: WebMD: http://www.webmd.com/diabetes/news/20150325/study-ties-frequent-antibiotic-use-to-higher- odds-for-type-2-diabetes

WPIX – March 25 The Jolie effect: Preventing ovarian cancer Actress Angelina Jolie opened up about having the BRCA-1 gene removed to help prevent her from getting ovarian cancer like her aunt, mother and grandmother. Dr. David Fishman, a gynecologic oncologist from Mount Sinai Hospital talks about the advantages of removing the gene. - Dr. David Fishman, Professor, Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai, Director, Mount Sinai Ovarian Cancer Risk Assessment Program, The Mount Sinai Hospital Learn more: http://pix11.com/2015/03/25/the-jolie-effect-preventing-ovarian-cancer/

Today Show – March 25 How Daisy Lewellyn battled cancer in the public eye / 3 Beautiful cancer survivors treated at Mount Sinai Receive Makeover Daisy Lewellyn, star of Bravo’s “Blood, Sweat and Heels,” shares how she battled cancer in front of the camera and how her work helped her get through one of the toughest times in her life. “I wanted people to know that no matter what comes your way, you can make it,” said Lewellyn. On the show, Lewellyn styled three cancer survivors with makeovers. “My guests and I all have the same doctor at Mount Sinai.” Learn more: http://www.today.com/klgandhoda/how-daisy-lewellyn-battled-cancer-public-eye- 2D80569160 Additional video: http://www.today.com/klgandhoda/daisy-lewellyn-styles-3-beautiful-cancer- survivors-2D80569161

ABC News – March 25 Angelina Jolie's Surgery and What You Should Know In a moving and personal op-ed piece, Angelina Jolie announced today that she has undergone surgery to remove her ovaries and fallopian tubes as a preventative measure to lower her risk of cancer. The actress had planned to have the surgery, but went ahead with it earlier than expected after a test indicated she could be at risk for a tumor. Experts say they appreciate how the actress and humanitarian has shined a light on the choice that thousands of women are forced to decide in their lifetime whether to go through a life-changing surgery or live with the risk. ABC News spoke with a number of experts to look at the surgery Jolie underwent and its effects. By removing the ovaries in the operation, women will end up going into early menopause. Side effects of early menopause can initially include hot flashes, mood swings and sleep problems. While hormone-replacement therapy can help, going into early menopause can increase risks for a number of other conditions including osteoporosis and heart disease, according to Dr. Laura Corio, an obstetrician-gynecologist and clinical professor at Mt. Sinai Hospital in New York City. “There’s risk factors about going through menopause; you have to worry about bones and heart,” Corio said, adding that early menopause can also raise the risk of colon cancer. - Laura Corio, MD, Assistant Clinical Professor, Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai Learn more: http://abcnews.go.com/Health/angelina-jolies-surgery/story?id=29865394

AccuWeather – March 26 Spring Allergies: Quick-Hitting, Intense Season in Store for East – Jillian MacMath Though springlike weather has been slow to arrive for much of the Eastern United States, allergy sufferers may soon pay the price for winter's unhurried retreat. Prolonged winter weather, like much of the Northeast has seen, can sometimes delay the start of tree pollination, according to Dr. Mauli Desai, division of Allergy and Clinical Immunology at Mount Sinai. Delayed pollination ultimately delays the onset of spring allergies, but that doesn't mean the season will be mild overall. - Mauli Desai, MD, Assistant Professor, Medicine, Clinical Immunology, Icahn School of Medicine at Mount Sinai Learn more: http://www.accuweather.com/en/weather-news/spring-allergy-pollen-forecast- 2015/44514851

The Fashion Spot – March 25 Angelina Jolie’s Powerful Decision to Remove Ovaries Resonates with Cancer Experts, Survivors – Beth Stebner In a moving piece in Monday’s The New York Times, actress and activist Angelina Jolie wrote of her second radical operation that saw her remove her ovaries and fallopian tubes, two years after electing to have a double mastectomy. Experts are praising the Hollywood A-lister’s bravery and courage as well as encouraging other women to get tested for the BRCA1 gene mutation and take prophylactic measures to fight the deadly disease. Dr. David Fishman, a gynecologic oncologist and director of the Mount Sinai Ovarian Cancer Risk Assessment Program, agrees. “Jolie is heroic, and should be applauded for making a private issue public,” he says. - Dr. David Fishman, Professor, Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai, Director, Mount Sinai Ovarian Cancer Risk Assessment Program, The Mount Sinai Hospital Learn more: http://www.thefashionspot.com/wellness/563795-angelina-jolies-decision-to-remove- ovaries-resonates/

Oxygen Magazine – March 25 3 Simple Steps for Recovery – Carey Rossi You work hard inside and outside of the gym, but do you ever really recover? As we go, go, go, sometimes we forget that we need to heal, heal, heal our bodies. Use these three keys—nourishment, time and sleep—to make sure that your body gets the TLC it needs to recoup so it can continue to perform at the level you want it. The first step for proper recovery is to eat something after your workout. “Eating immediately after is important for recovery after any workout,” says Joseph E. Herrera, MD, director of sports medicine at Mount Sinai School of Medicine in New York. “The optimal time to replenish any energy stores is within the first 15 to 30 minutes after a workout.” - Joseph Herrera, DO, Assistant Professor, Rehabilitation Medicine, Icahn School of Medicine at Mount Sinai Learn more: http://www.oxygenmag.com/article/3-simple-steps-recovery-9937

Yahoo! – March 24 6 Things You Absolutely Must Tell Your Gynecologist It’s really tempting to lie to your gyno. You’re embarrassed, you feel awkward, or maybe you just think it’s none of her business. But lying to them (or lying by omission) could be hurting your health. I called up Rebecca C. Brightman, an ob-gyn in clinical practice, to tell you which things you need to get real about with your gyno. -Rebecca Brightman, MD, Assistant Clinical Professor, Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai Learn more: https://www.yahoo.com/health/6-things-you-absolutely-must-tell-your-114148345188.html

Happi – March 25 AAD Appoints Lebwohl As President The American Academy of Dermatology (Academy): named Mark G. Lebwohl, MD, as its president at the conclusion of the Academy’s 73rd Annual Meeting in San Francisco, CA. He will hold the office of president for one year. "I am honored to assume this position, and will use my term to serve as an advocate for patients," said Dr. Lebwohl. "Quality care will be the focus of my presidency." Dr. Lebwohl completed residencies in internal medicine and dermatology at Mount Sinai and has been practicing dermatology since 1983. He has transformed Mount Sinai's Dermatology Department from a faculty of two to one of the largest in the nation, with more than 40 paid faculty and nearly 250 voluntary faculty members. -Mark Lebwohl, MD, Sol and Clara Kest Professor of Dermatology, System Chair, Dermatology, Icahn School of Medicine at Mount Sinai, the Mount Sinai Health System Learn more: http://www.happi.com/contents/view_breaking-news/2015-03-25/aad-appoints-lebwohl-as- president/

The Atlantic – March 16 Phineas Gage, Gauging Time – Cody Delistraty Why do people feel the hours pass more slowly or quickly than they really do? Heather Berlin, PhD, Assistant Professor of Neuroscience and Psychiatry, Icahn School of Medicine at Mount Sinai, conducted a study of time perception during graduate school by having participants read index cards with random numbers printed on them, then asking the participants how long they thought the task had lasted. Reading the numbers out loud kept participants from counting to keep track of time. In a digitized version of the experiment on her tablet computer, Berlin spoke to healthy people and people with orbitofrontal cortex lesions and subjected them all to her digitized time-perception test. Berlin asked participants to tell her when they believed 90 seconds had passed as she distracted them with the randomized numbers. Participants with undamaged brains tended to let a few more than 90 seconds pass before stopping her, indicating a slightly slower perception of time. Participants with orbitofrontal cortex damage, however, would stop her at almost exactly 90 seconds, indicating a more accurate perception of time. -Heather Berlin, PhD, Assistant Professor of Neuroscience and Psychiatry, Icahn School of Medicine at Mount Sinai Learn more: http://www.theatlantic.com/health/archive/2015/03/phineas-gage-gauging-time/387469/

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: [email protected] on behalf of Lindo, Allisa Subject: Mount Sinai In The News - March 25, 2015 Date: Wednesday, March 25, 2015 12:28:13 PM Attachments: ATT00001.txt

In the News March 25, 2015

Scientific American – March 24 Why Don't Animals Get Schizophrenia (and How Come We Do)? – Bret Stetka Science suggests that numerous non-human species suffer from psychiatric symptoms. But there’s at least one mental malady that, while common in humans, seems to have spared all other animals: schizophrenia. Though psychotic animals may exist, psychosis has never been observed outside of our own species. A new study provides clues into how the potential for schizophrenia may have arisen in the human brain and, in doing so, suggests possible treatment targets. It turns out psychosis may be an unfortunate cost of our big brains—of higher, complex cognition. The study, led by researcher Joel Dudley, PhD, of the Icahn School of Medicine at Mount Sinai proposed that since schizophrenia is relatively prevalent in humans despite being so detrimental—the condition affects over 1% of adults— that it perhaps has a complex evolutionary backstory that would explain its persistence and exclusivity to humans. - Joel Dudley, PhD, Assistant Professor, Genetics and Genomic Sciences, Population Health Science Policy, Icahn School of Medicine at Mount Sinai Learn more: http://www.scientificamerican.com/article/why-don-t-animals-get-schizophrenia-and-how- come-we-do/

Health Canal – March 24 Mount Sinai First in the East to Implant the WATCHMAN Device to Prevent Stroke in Atrial Fibrillation Patients The Mount Sinai Hospital experts were the first in the Eastern United States on March 23 to implant a newly FDA-approved device that prevents stroke in patients with arrhythmia. The WATCHMAN device, the size of a quarter and shaped like a parachute, is implanted into the heart to close off the left- atrial appendage, a blind pouch of heart tissue where blood clots form and can then break off and travel in the blood stream to the brain and cause strokes. "Blood-thinning medications like warfarin or Coumadin are quite effective in reducing the risk for stroke in patients with atrial fibrillation. However, many of our patients cannot, or will not, tolerate these medications because of the incidence of bleeding. The WATCHMAN device is a solution for such atrial fibrillation patients, since it similarly reduces their stroke risk, but averts their need for a lifetime of blood-thinners," says the electrophysiologist who led the procedure, Vivek Reddy, MD, Director of Arrhythmia Services at The Mount Sinai Hospital and the Mount Sinai Health System. - Dr. Vivek Reddy, Professor Medicine, Cardiology, Icahn School of Medicine at Mount Sinai, Director, Arrhythmia Services, Mount Sinai Health System Learn more: http://www.healthcanal.com/brain-nerves/stroke/61637-mount-sinai-first-in-the-east-to- implant-the-watchman-device-to-prevent-stroke-in-atrial-fibrillation-patients.html

Crain’s Health Pulse – March 25 Mount Sinai, Philips Deal What’s the best use of hundreds of thousands of patient tissue samples stored over the years? Digitize them, and squeeze out the data. The Mount Sinai Health System yesterday announced a joint development agreement with Royal Philips to create a digital image repository of those glass tissue slides. The terms of the agreement were hammered out by Mount Sinai Innovation Partners, the health system’s technology development and commercialization group. Philips and Mount Sinai will analyze the data and view it within the context of other images, results and clinical information in the hope of developing predictive analytics that researchers can use for personalized medicine. - Mount Sinai Health System Learn more: http://www.crainsnewyork.com/article/20150325/PULSE/150329936/federal-doc-fix-earns- hospitals-praise# Additional Coverage: DOTmed: http://www.dotmed.com/news/story/25389 The Financial: http://finchannel.com/index.php/technology/item/41867-philips-and-mount-sinai-health- system-collaborate Zonebourse (France): http://www.zonebourse.com/PHILIPS-6289/actualite/Philips--collaboration-dans- la-recherche-avec-le-Mount-Sinai-20077591/ [Article is in French]

The Washington Post – March 24 The Angelina Jolie Effect: When a Sex Symbol Removes Her Ovaries to Prevent Cancer, Women More Likely to Follow – Danielle Paquette Angelina Jolie, mother of six, whipped the Internet into a frenzy Tuesday after announcing her decision to have her ovaries removed in an elective surgery meant to prevent cancer. “I feel feminine, and grounded in the choices I am making for myself and my family,” the actress wrote in a powerful op-ed for the New York Times. “I know my children will never have to say, ‘Mom died of ovarian cancer.’” Doctors say the buzz will likely drive more women to consider genetic testing and, perhaps, elective surgeries that research shows can drastically reduce the risk of cancer. Researchers have dubbed this phenomenon “the Angelina Jolie effect.” “A Nobel laureate could give the same message, and it might reach only a handful of people,” said David Fishman, MD, director of the Mount Sinai Ovarian Cancer Risk Assessment Program in New York City. “Angelina is using her celebrity in a heroic way, and she’s going to reach millions of people worldwide.” - Dr. David Fishman, Professor, Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai, Director, Mount Sinai Ovarian Cancer Risk Assessment Program, The Mount Sinai Hospital Learn more: http://www.washingtonpost.com/blogs/wonkblog/wp/2015/03/24/the-angelina-jolie-effect- when-a-sex-symbol-removes-her-ovaries-to-prevent-cancer-other-women-more-likely-to-follow/ Additional Coverage: HealthDay: http://consumer.healthday.com/cancer-information-5/mis-cancer-news-102/angelina-jolie-s- choice-not-uncommon-for-women-with-cancer-gene-experts-say-697723.html U.S. News & World Report: http://health.usnews.com/health-news/articles/2015/03/24/angelina-jolies- choice-not-uncommon-for-women-with-cancer-gene The New York Daily News: http://www.nydailynews.com/life-style/health/angelina-jolie-surgery- article-1.2160538 The New York Daily News: http://www.nydailynews.com/entertainment/movies/angelina-jolie-wins- praise-ovarian-cancer-decision-article-1.2161362 The Star (Canada): http://www.thestar.com/life/health_wellness/2015/03/24/the-angelina-jolie-effect.html Newsmax: http://www.newsmax.com/Health/Headline/jolie-angelina-cancer- surgery/2015/03/24/id/634256/

USA Today – March 24 'Jolie Effect': Could Her Candor Help Save Lives? – Maria Puente Angelina Jolie, an otherwise fairly discreet mega-movie star, falls into the latter category. Jolie published Tuesday another candid essay on why she chose surgery to remove her ovaries and fallopian tubes: to help reduce her chances of getting killer cancers after genetic testing suggested she was at an elevated risk. Telling the world about it again means she's brought attention to scary female cancers that are hard to detect until it's too late and, just as important, she raises the issue of genetic testing for women who might be at greater risk of getting them. "This puts a very positive spin on the genetic testing-and-results arena," says Susan Boolbol, MD, chief of breast surgery at Mount Sinai Beth Israel Hospital in New York. "Because her message, which should be everyone's message, is this is my personal choice, it's not the right choice for everyone but we should all be aware of our options. Knowledge is power, that's what I say to my patients every day," Boolbol says. - Dr. Susan Boolbol, Associate Professor, Surgery, Icahn School of Medicine at Mount Sinai, Chief, Breast Surgery, Mount Sinai Beth Israel Learn more: http://www.usatoday.com/story/life/movies/2015/03/24/angelina-jolie-alerts-women-to- cancer-threat-again/70372166/ Additional Coverage: Yahoo Health: https://www.yahoo.com/health/why-angelina-jolie-pitt-underwent-preventive- 114494026372.html Yahoo Canada: https://ca.news.yahoo.com/why-angelina-jolie-pitt-underwent-preventive-surgery-to- remove-her-ovaries-183607293.html TV5 Monde (France): http://information.tv5monde.com/terriennes/angelina-jolie-journal-de-campagne- contre-le-cancer-24317 [Article is in French] WNYW TV: No Web Link Available

CBS News Up To The Minute – March 24 Cutting Cancer Risk Nimesh Nagarsheth, MD, a gynecological oncologist at The Mount Sinai Hospital in New York City, discusses Angelina Jolie’s choice to have preventive surgeries to lower her cancer risk and options for women to consider. Jolie’s doctors informed her that a genetic mutation increased her chances of having cancer. “BRCA mutation is a genetic mutation in the BRCA gene. It predisposes you to certain types of cancers, breast cancer, ovarian cancer, as well as other types of cancers we don’t hear much about such as prostate and pancreatic cancer,” says Dr. Nagarsheth. - Dr. Nimesh Nagarsheth, Associate Professor, Obstetrics, Gynecology and Reproductive Science, Associate Director, Gynecologic Oncology, Icahn School of Medicine at Mount Sinai Learn more: http://www.cbsnews.com/videos/cutting-cancer-risk/ Additional Coverage: Yahoo News: http://news.yahoo.com/video/cutting-cancer-risk-085834626-cbs.html

WPIX – March 24 Fighting Ovarian Cancer – Jay Dow More than 20,000 women every single year are diagnosed with ovarian cancer. More than three-quarters of those women are already in the late stages. There is simply no way to catch it early. Angelina Jolie- Pitt is in the news again, not for her acting or directing, but for another prophylactic, or preventive, surgery she chose to have, this time to remove her ovaries and fallopian tubes all in the hopes of avoiding a fight with cancer. “Right now we don’t have a great screening test for ovarian and fallopian tube cancer,” says Monica Prasad-Hayes, MD, a gynecologic oncologist at The Mount Sinai Hospital, “Because of the high increased risk in this population of patients who have a genetic mutation, we do recommend that they have this surgery.” - Dr. Monica Prasad-Hayes, Assistant Professor, Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai Learn more: https://www.youtube.com/watch?v=R30I1qJS-lk

Globo TV (Brazil) – March 24 Angelina Jolie Announces Extraction of Ovaries and Fallopian Tubes to Prevent Cancer The actress Angelina Jolie published an article in The New York Times on Tuesday that provoked discussion all day. To prevent cancer, she decided to remove her ovaries and fallopian tubes. The surgery to remove the ovaries and fallopian tubes is relatively simple, but there are important consequences. The ovaries are responsible for producing the hormones estrogen and progesterone, which a lack thereof means the arrival of menopause. Gynecologist Lisa Anderson, MD, of The Mount Sinai Hospital in New York, says, "Research indicates that the most aggressive types of ovarian cancer arise in the fallopian tubes and are hardly detected on imaging studies with high risk. At 39 years old and after having children, I believe that Angelina did the right thing. " - Dr. Lisa Anderson, Assistant Professor, Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai Learn more: http://g1.globo.com/jornal-nacional/noticia/2015/03/angelina-jolie-anuncia-extracao-de- ovarios-e-trompas-para-evitar-cancer.html [Article is in Portuguese]

WCBS TV – March 24 Vitamin D Deficiency – Max Gomez Weather can affect more than your mood, it can also affect your body, specifically Vitamin D. Vitamin D is important for bone health because you need it to absorb calcium. Doctors are now learning that Vitamin D may also be important for heart health, your mood, and may even help prevent cancer. Low Vitamin D has been associated with high blood pressure, but taking Vitamin D supplements did not lower blood pressure in a recent study, so some cardiologists have been a little skeptical about it. But they say there are still suggestions that it’s good for your heart. “Vitamin D supplementation reduces inflammation and decreases cholesterol uptake,” says Robert Rosenson, MD, a cardiologist at The Mount Sinai Hospital. - Dr. Robert Rosenson, Professor, Medicine, Cardiology, Icahn School of Medicine at Mount Sinai, Director, Cardiometabolic Unit, The Mount Sinai Hospital Learn more: http://newyork.cbslocal.com/video/11271776-dr-max-gomez-vitamin-d-deficiency/

WCBS 880 – March 18 9/11 Rescue Workers at Heightened Risk for Autoimmune Diseases, Study Claims – Peter Haskell The longer rescue workers were at Ground Zero, the more likely they are to have an autoimmune disease, according to a new study. The study found the risk jumped 13 percent for each month at the site. Michael Crane was not involved in the research, but heads the World Trade Center Health Program at The Mount Sinai Hospital. “Very important, because it shows us that even lower dose exposure later on to the dust maybe very, very important,” he told WCBS 880’s Peter Haskell. - Dr. Michael Crane, Assistant Professor, Preventive Medicine, Icahn School of Medicine at Mount Sinai, Medical Director, the World Trade Center Health Program at Mount Sinai, the Mount Sinai Hospital Learn more: http://newyork.cbslocal.com/2015/03/18/911-rescue-workers-at-heightened-risk-for- autoimmune-diseases-study-claims/

The Fashion Spot – March 24 Is Waist Training Really a Cinch? Here Are 10 Things to Know about Corsets – Beth Stebner Corsets have been cinching their way into the news of late, first with celebrities like the Kardashian sisters touting its slimming merits while exercising, not to mention a media firestorm about Cinderella star Lily James’ dainty waist. But how safe is so-called “waist training,” where women squeeze themselves into a restrictive garment to achieve the much sought-after hourglass shape? Many women use corsets to achieve a thinner midsection or to help them recover after giving birth. But there are some risks, including putting extra pressure on your stomach, intestines and your colon, according to Gina Sam, MD, an assistant professor of medicine and gastroenterology at the Icahn School of Medicine at Mount Sinai. “It can also cause abdominal discomfort and heartburn if the pressure is extremely tight,” she says. - Dr. Gina Sam, Assistant Professor, Medicine, Gastroenterology, Icahn School of Medicine at Mount Sinai, Director, Mount Sinai Gastrointestinal Motility Center at the Mount Sinai Hospital Learn more: http://www.thefashionspot.com/life/563299-10-things-to-know-about-corset-training/

Naples Herald – March 25 People Breathe A Little Easier in Naples, According to Study – Rebecca Boreczky For the ninth consecutive year, the Asthma and Allergy Foundation of America (AAFA) has released its list of best and worst cities for allergies in the nation. Researchers analyzed 100 metro areas in the United States, measuring pollen levels, retail sales of prescription and over-the-counter allergy medicines and the number of board certified allergists per patient. Naples is in the top five. According to Beth Corn, MD, Director of the Allergy and Asthma Clinic in New York’s The Mount Sinai Hospital, ocean breezes help clear the air of allergens. - Dr. Beth Corn, Associate Professor, Medicine, Clinical Immunology, Icahn School of Medicine at Mount Sinai, Director, Allergy and Asthma Clinic, The Mount Sinai Hospital Learn more: http://naplesherald.com/2015/03/25/people-breathe-a-little-easier-in-naples-according-to- study/

KK (Norway) – March 25 Replacing Protein Shake with Milk – Silje Førsund Just when you thought the world could not be weirder, comes mildly peculiar news about bodybuilders who drink breast milk. According to the British newspaper The Telegraph it is no longer just young children who drink milk anymore. The newspaper confirms the British fitness coach Troy Martin at TM Fitness, that breast milk also drinking among adults in certain training environments. “There is nothing in breast milk that will help people build muscle mass,” Jacques Moritz, MD, physician and director of the department of gynecology at Mount Sinai Roosevelt said to ABC News. - Dr. Jacques Moritz, Assistant Professor, Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai, Director, Gynecology, Mount Sinai St. Luke’s and Mount Sinai Roosevelt Learn more: http://www.kk.no/trening/bytter-ut-proteinshake-med-brystmelk-32939 [Article is in Norwegian]

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: [email protected] on behalf of Lindo, Allisa Subject: Mount Sinai In The News - March 24, 2015 Date: Tuesday, March 24, 2015 11:09:42 AM Attachments: ATT00001.txt

In the News March 24, 2015

Oncology Nurse Advisor – March 24 Chemotherapy After Bladder Cancer Surgery Improves Survival – Kathy Boltz, PhD Patients who received chemotherapy after bladder cancer surgery demonstrated an approximately 30% lower risk of death than those who underwent surgery alone. This analysis was presented at the 2015 Genitourinary Cancers Symposium in Orlando, Florida. Lead researcher Matthew Galsky, MD, and colleagues from the Icahn School of Medicine at Mount Sinai in New York, New York, used a large database of patients with a cancer diagnosis in the United States. Specifically, the study found that patients receiving adjuvant chemotherapy after surgery had improved overall survival compared with patients who underwent surgery with only postsurgical observation. "Until now, data supporting adjuvant chemotherapy has been mixed," said Galsky, associate professor of medicine, Hematology and Medical Oncology, and assistant professor, Urology at the Icahn School of Medicine at Mount Sinai. - Dr. Matthew Galsky, Associate Professor, Medicine, Hematology and Medical Oncology, Assistant Professor, Urology, Icahn School of Medicine at Mount Sinai Learn more: http://www.oncologynurseadvisor.com/chemotherapy-after-bladder-cancer-surgery- improves-survival/article/404952/

New York Magazine – March 24 What a Neuroscientist Said about Jon Stewart’s Brain – Melissa Dahl Watching a comedy show with Heather Berlin, PhD, a neuroscientist at The Mount Sinai Hospital, must be a strange experience. You (and everyone else in the room) are focused on the jokes; Berlin, on the other hand, is mostly curious about the brain responsible for creating those jokes. Previously, Berlin has used brain scanners to peer into the minds of rappers, to see what happens when the musicians are freestyling as compared to performing memorized material, similar to studies other researchers have done, with similar results, on improvisational jazz musicians. "We want to add in the comedy group to see if there is actually some kind of neural signature of spontaneous creativity — something that looks the same, across different disciplines," she said. -Heather Berlin, PhD, Assistant Professor, Psychiatry, Neuroscience, Icahn School of Medicine at Mount Sinai Learn more: http://nymag.com/scienceofus/2015/03/neuroscientist-on-jon-stewarts-brain.html

WPIX – March 24 Miracle Cures for 5 Degenerative Diseases According to Popular Science’s “Yes, You Can Reverse Disease” report, scientists are turning back the clock on these five health problems including heart failure. A failing heart leaves people tired, weak, and short of breath. Some ultimately need a transplant. But soon, there may be another option: gene therapy. In order to beat, a heart’s muscle cells must contract and relax. To contract, calcium ions flow out of the cells through a special organelle. To relax, a protein called SERCA2a pumps them back in. Failing hearts tend to have less of this protein than normal hearts, so Roger Hajjar, MD, a cardiologist at The Mount Sinai Hospital in New York, developed a way to deliver more. His lab engineered a virus to carry extra copies of the gene that codes for SERCA2a into heart cells and insert them into the DNA. Consequently, the cells increase SERCA2a production. Although the protein can’t undo existing damage, it can help the remaining cells work harder. - Dr. Roger Hajjar, Arthur and Janet C. Ross Professor of Medicine, Cardiology, Icahn School of Medicine at Mount Sinai, Director, Cardiovascular Research Center, The Mount Sinai Hospital Learn more: http://pix11.com/2015/03/24/miracle-cures-for-5-degenerative-diseases/

HealthDay – March 23 Latest Diabetes Care Guidelines Focus on Individual Approach – Serena Gordon When caring for people with diabetes, primary care doctors need to tailor blood sugar targets and treatments to the individual patient, new recommendations suggest. That's just one of the guidelines highlighted in an article that experts from the Joslin Diabetes Center in Boston published in the March 23 issue of the Annals of Internal Medicine. Sam Altstein, MD, a family medicine doctor and medical director of the Mount Sinai Beth Israel Medical Group in New York City, said none of the recommendations would be difficult to incorporate into practice. "Doctors are very good at tailoring treatment to specific individuals. Patients don't always fit into algorithms -- they may be elderly or very sick -- so, we have to make adjustments," Altstein said. -Dr. Sam Altstein, Medical Director, Mount Sinai Beth Israel Medical Group Learn more: http://consumer.healthday.com/diabetes-information-10/diabetes-drug-news-179/latest- diabetes-care-guidelines-focus-on-individual-care-697675.html

Yahoo Health – March 24 9 Kidney Stone Myths to Stop Believing – Ashley Macha Getting a kidney stone is no walk in the park. And the rumors floating around about what to expect when the stone actually passes are not for the faint of heart. So how can you be certain the pain you’re experiencing is legitimately a kidney stone? What’s the difference between a kidney stone versus appendicitis versus a urinary tract infection — or even a good old-fashioned stomachache? That’s why it’s important to know what you’re dealing with, says Mantu Gupta, MD, director of The Kidney Stone Center at The Mount Sinai Hospital, who comes across a lot of misconceptions when it comes to signs, symptoms, feel, and care of kidney stones. - Dr. Mantu Gupta, Senior Faculty, Urology, Icahn School of Medicine at Mount Sinai, Site Chair, Urology, Mount Sinai Roosevelt, Mount Sinai St. Luke’s, Director, The Kidney Stone Center, The Mount Sinai Hospital, Director, Endourology and Stone Disease, Mount Sinai Health System Learn more: https://www.yahoo.com/health/9-kidney-stone-myths-to-stop-believing-114406607242.html

Redbook – March 24 How to Change Your Body Shape in One Afternoon – Lindsy Van Gelder Raise your hand if you can relate to this: You have a muffin top, a tummy pooch, or stretch marks (yeah, our hands are up high too). Whether your trouble spot came from having kids or plain old genetics, you know how stubborn it is to lose. New body- shaping treatments performed by a dermatologist, such as lasers and radio frequency, can melt fat, tighten saggy skin, and fade stretch marks. And while these technologies aren't cheap, "they come without the health risks or lengthy downtime of plastic surgery," says Angela Lamb, MD, director of the Westside Mount Sinai Dermatology Faculty Practice at The Mount Sinai Hospital in New York City. - Dr. Angela Lamb, Assistant Professor, Dermatology, Icahn School of Medicine at Mount Sinai, Director, Westside Mount Sinai Dermatology Practice Faculty Practice Learn more: http://www.redbookmag.com/body/health-fitness/a21012/how-to-change-your-body- shape-in-one-afternoon/

Boston.com – March 22 Coconut Oil: Should You Eat It or Wear It? – Joan Salge Blake Coconut oil does have a number of benefits for both your skin and hair. According to Whitney Bowe, MD, Clinical Assistant Professor of Dermatology at the Icahn School of Medicine at Mount Sinai Medical Center, and member of the American Academy of Dermatology, coconut oil has a combination of hydrating, anti-inflammatory, antioxidant, and antibacterial properties that make it a wonderful ingredient to incorporate into your skin and hair care routine. “The MCTs in coconut oil help to repair the skin barrier and trap water, thus, hydrating the skin and reducing inflammation," Bowe said in an email with Boston.com. - Dr. Whitney Bowe, Assistant Clinical Professor, Dermatology, Icahn School of Medicine at Mount Sinai Learn more: http://www.boston.com/lifestyle/health/blog/nutrition/2015/03/post.html

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: [email protected] on behalf of Lindo, Allisa Subject: Mount Sinai In The News - March 23, 2015 Date: Monday, March 23, 2015 12:23:02 PM Attachments: ATT00001.txt

In the News March 23, 2015

Crain’s New York Business – March 20 Meet Harlem's $238 Million Cancer Killer – Barbara Benson Since 2009, local cancer specialists have dreamed of building a mecca for proton-beam therapy in Manhattan. Next week, that dream, the $238 million New York Proton Center, will take a step closer to reality as health officials gear up to vote on its merits at a public hearing. The New York Proton Center will be built by some of the biggest names in health care: Memorial Sloan Kettering Cancer Center, Mount Sinai Health System, Montefiore Health System and UnitedHealth Group are all investors in the massive project. - Mount Sinai Health System Learn more: http://www.crainsnewyork.com/article/20150320/HEALTH_CARE/150329991/meet- harlems-238-million-cancer-killer

NBC Nightly News – March 20 Alzheimer’s Drug – Kate Snow There is encouraging news to report tonight in the fight against Alzheimer’s. While there is no truly effective treatment, the results from a new study are so promising they’ve caused something of a stir. A new drug being is called a potential silver bullet to slow down memory loss. “This is the first evidence that we can modify the progression of Alzheimer’s. I think that’s very encouraging indeed,” Samuel Gandy, MD, of The Mount Sinai Hospital told NBC News’ Kate Snow. - Dr. Samuel Gandy, Professor, Neurology, Psychiatry, Icahn School of Medicine at Mount Sinai, Associate Director, Mount Sinai Alzheimer’s Disease Research Center Learn more: No Web Link Available

PBS Newshour – March 21 Newshour Weekend – Hari Sreenivasan On this edition for Saturday, March 21, 2015, a new drug shows early promise as a treatment for people with Alzheimer's Disease. Recently there was news about what could be a big step forward in the battle against Alzheimer’s, a new drug that during tests sharply slowed the cognitive decline of people with the debilitating disease. Joining PBS Newshour to discuss the drug is Samuel Gandy, MD, of The Mount Sinai Hospital. “The drug is aimed at material that builds up in the brain during Alzheimer’s,” says Dr. Gandy. - Dr. Samuel Gandy, Professor, Neurology, Psychiatry, Icahn School of Medicine at Mount Sinai, Associate Director, Mount Sinai Alzheimer’s Disease Research Center Learn more: http://www.thirteen.org/programs/pbs-newshour/

Modern Healthcare – March 21 New App Aids Mount Sinai Asthma Research – Darius Tahir The Mount Sinai Hospital had been working closely with mobile application developer LifeMap Solutions since the New York City-based firm was launched last May. Last summer computer giant Apple contacted Mount Sinai about creating a medical and research app that would work with its planned application programming interface (API) for its iPhone. So Mount Sinai researchers and clinicians worked with LifeMap to develop the Asthma Health app. Yvonne Chan, MD, director of personalized medicine and digital health at Mount Sinai, said she and her colleagues are using the Asthma Health app as part of a study to determine whether there are geographical and environmental connections to asthma attacks. - Dr. Yvonne Chan, Assistant Professor, Genetics and Genomic Sciences, Emergency Medicine, Director, Personalized Medicine and Digital Health, Icahn School of Medicine at Mount Sinai Learn more: http://www.modernhealthcare.com/article/20150321/MAGAZINE/303219927/new-app-aids- mount-sinai-asthma-research

Medpage Today – March 22 IL-17 Inhibitor Clears Psoriasis More Often – Charles Bankhead Twice as many patients with plaque psoriasis had complete clearance of lesions treated with an investigational interleukin-17 inhibitor as compared with ustekinumab (Stelara), according to a study reported here. For the most part, early responses to brodalumab were maintained during follow-up to 52 weeks, Mark Lebwohl, MD, of the Icahn School of Medicine at Mount Sinai in New York City, reported at the American Academy of Dermatology meeting. "Brodalumab resulted in significant clinical improvement in moderate to severe plaque psoriasis, and brodalumab 210 mg administered every 2 weeks demonstrated superiority to ustekinumab in achieving PASI 100 response," Lebwohl said. - Dr. Mark Lebwohl, Sol and Clara Kest Professor of Dermatology, System Chair, Dermatology, Icahn School of Medicine at Mount Sinai, the Mount Sinai Health System Learn more: http://www.medpagetoday.com/MeetingCoverage/AAD/50605

Diabetes in Control – March 20 Novel Drug Candidate Regenerates Pancreatic Cells Lost in Diabetes The Mount Sinai study found that harmine drove the sustained division and multiplication of adult human beta cells in culture. In addition, harmine treatment tripled the number of beta cells and led to better control of blood sugar in three groups of mice engineered to mimic human diabetes. Senior study author Andrew Stewart, MD, Director of the Diabetes, Obesity and Metabolism Institute at the Icahn School of Medicine, said that, "Our results provide a large body of evidence demonstrating that the harmine drug class can make human beta cells proliferate at levels that may be relevant for diabetes treatment." - Dr. Andrew Stewart, Professor, Medicine, Endocrinology, Diabetes and Bone Disease, Director, Diabetes, Obesity and Metabolism Institute, Icahn School of Medicine at Mount Sinai -Peng Wang, PhD, Assistant Professor, Medicine, Endocrinology, Diabetes and Bone Disease, Icahn School of Medicine at Mount Sinai Learn more: http://www.diabetesincontrol.com/articles/diabetes-news/17706-novel-drug-candidate- regenerates-pancreatic-cells-lost-in-diabetes

Medpage Today – March 20 PEGASUS-TIMI 54 Trial: Valentin Fuster, MD Valentin Fuster, MD, sits down with Medpage Today to discuss prevention of cardiovascular events in patients with prior heart attack using Ticagrelor compared to placebo on a background of aspirin (PEGASUS) -Thrombolysis in Myocardial Infarction (TIMI) 54. “The question is an economic one. I have to see the issue of bleeding, the cost of the drug, and where the patient comes from,” says Dr. Fuster. He continues, “80% of heart attacks take place in middle and low income countries.” - Dr. Valentin Fuster, Professor, Medicine, Cardiology, Icahn School of Medicine at Mount Sinai, Director, Mount Sinai Heart, the Zena and Michael A. Wiener Cardiovascular Institute, the Marie-Josée and Henry R. Kravis Center for Cardiovascular Health Learn more: http://www.medpagetoday.com/ACC2015VideoOnTheScene/Cardiology/ACC-Videos/1032

Reuters – March 19 Mexican-Americans' Atherosclerosis Tied To Cardiometabolics More Than BMI – Lisa Rapaport In Mexican-Americans, cardiometabolic risk has a greater effect on early atherosclerosis development than body mass index (BMI), a study finds. "Everyone talks about the dangers of obesity, but now new research shows that several cardiometabolic risk factors that may be the result of obesity are more dangerous than obesity alone if it is devoid of such factors," Valentin Fuster, MD, director of Mount Sinai Heart Hospital in New York, told Reuters Health in an email. "What is really putting Mexican- Americans' heart health at risk for coronary artery disease is the presence of several cardiometabolic risk factors, not necessarily obesity without such risk factors," said Dr. Fuster, who wasn't involved with the study. - Dr. Valentin Fuster, Professor, Medicine, Cardiology, Icahn School of Medicine at Mount Sinai, Director, Mount Sinai Heart, the Zena and Michael A. Wiener Cardiovascular Institute, the Marie-Josée and Henry R. Kravis Center for Cardiovascular Health Learn more: No Web Link Available

Medscape – March 17 The Cardiology Show From ACC 2015 With Valentin Fuster, MD From the American College of Cardiology 2015 Scientific Sessions in sunny San Diego, Valentin Fuster, MD, reviews CT angiography in PROMISE and SCOT-HEART, ticagrelor in PEGASUS, the injectable PSCK9 inhibitors, and a range of interventional cardiology trials (MATRIX, TOTAL, PARTNER). However, the study that packs the biggest punch is one on weight loss in patients with atrial fibrillation. “This is a very well done study,” remarks Dr. Fuster. - Dr. Valentin Fuster, Professor, Medicine, Cardiology, Icahn School of Medicine at Mount Sinai, Director, Mount Sinai Heart, the Zena and Michael A. Wiener Cardiovascular Institute, the Marie-Josée and Henry R. Kravis Center for Cardiovascular Health Learn more: http://www.medscape.com/viewarticle/841475 [Login Required]

HealthDay – March 20 Urine Test Shows Promise for Early Diagnosis of Kidney Cancer – Robert Preidt A urine test might someday become a much-needed early detection test for kidney cancer, a new study suggests. "This research is very important and a significant finding, because we do not have a good screening mechanism for kidney cancer," said one expert, Ketan Badani, MD, professor of urology at the Icahn School of Medicine in New York City. However, if the cancer is not spotted until after it has spread, 80 percent of patients die within five years. According to the researchers, finding the disease early -- before it has spread -- has remained a major challenge. - Dr. Ketan Badani, Senior Faculty, Urology, Icahn School of Medicine at Mount Sinai, Director, Comprehensive Kidney Cancer Program, Vice Chairman, Urology and Robotic Operations, Mount Sinai Health System Learn more: http://consumer.healthday.com/cancer-information-5/kidney-cancer-news-431/urine-test- shows-promise-for-early-diagnosis-of-kidney-cancer-697607.html Additional Coverage: U.S. News & World Report: http://health.usnews.com/health-news/articles/2015/03/20/urine-test-shows- promise-for-early-diagnosis-of-kidney-cancer WebMD: http://www.webmd.com/cancer/news/20150320/urine-test-shows-promise-for-early-diagnosis- of-kidney-cancer Doctors Lounge: http://www.doctorslounge.com/index.php/news/hd/53882

Medical Technology Schools – March 22 25 Top Professors of Sonography Partho Sengupta not only directs the Cardiac Ultrasound Research and Core Lab, but he is an Associate Professor of Medicine in Cardiology at the Icahn School of Medicine at Mount Sinai. His clinical focus is Echocardiography and he is on the Board of Directors for the American Society of Echocardiography (ASE). He has won many awards including the ASE's Feigenbaum Lectureship for his contributions to research in electrocardiography. His groundbreaking work has been published many places, including Forbes Magazine. - Dr. Partho Sengupta, Associate Professor, Medicine, Cardiology, Icahn School of Medicine at Mount Sinai, Director, Cardiac Ultrasound Research and Core Lab, the Zena and Michael A. Wiener Cardiovascular Institute, the Marie-Josée and Henry R. Kravis Center for Cardiovascular Health Learn more: http://www.medicaltechnologyschools.com/ultrasound-technician/top-sonography- professors

Health – March 20 7 Life Events That Can Lead to Divorce – Amanda MacMillan Late last month, Boston Marathon bombing survivor Rebekah Gregory made headlines with the sad news that she was separating from her husband—who was also injured in the blast—less than one year after their dream wedding. Without knowing the couple, it’s probably safe to say that the stresses of the last few years may have played a role. And while not everyone has to deal with things this catastrophic, most couples do face plenty of stressors and life changes, both big and small. We asked Elizabeth Ochoa, PhD, marriage counselor and chief psychologist at Mount Sinai Beth Israel in New York City, to weigh in on life events that can sometimes lead to divorce—and how to protect your relationship from their harmful effects. “Illnesses create debt and pain and loss of self,” says Ochoa. “It can mean one partner isn’t able to maintain his or her part of the deal, which requires the other partner to step it up. Some couples will be better at dealing with that than others.” - Elizabeth Ochoa, PhD, Assistant Professor, Psychiatry, Icahn School of Medicine at Mount Sinai Learn more: http://news.health.com/2015/03/20/7-life-events-that-can-lead-to-divorce/

WNYW – March 20 New York Minute An emotional reaction from a medical student on Match Day after getting her first choice for medical residency. “I just had a baby on Sunday, found out I matched on Monday and got my first choice on Friday. This is the best week of my life,” she said. More than 129 medical students from the Icahn School of Medicine at Mount Sinai opened their envelopes together on Friday afternoon. - Icahn School of Medicine at Mount Sinai Learn more: No Web Link Available

Medscape – March 23 Powdered Alcohol: What's the Harm? – Pauline Anderson Substance abuse experts are concerned about the imminent availability of powered alcohol because of its health risks and abuse potential. The flavored, freeze-dried alcohol, which looks like powdered Jell-O, can be thrown into a back pocket and taken almost anywhere, according to Harris Stratyner, PhD, an associate professor of psychiatry, Icahn School of Medicine at Mount Sinai, New York City. "You don't have to carry around a bottle of alcohol if you're going camping or for a bike ride. And when you get to your destination, you just add water or mixer to reconstitute the alcohol ― and voilá, you've got an instant alcoholic beverage," he said. - Harris Stratyner, PhD, Associate Clinical Professor, Psychiatry, Icahn School of Medicine at Mount Sinai Learn more: http://www.medscape.com/viewarticle/841859

The New York Daily News – March 22 Spring is the Beginning of Allergy Season, says Dr. Mauli Desai of Mount Sinai – Katie Charles With the end of this tenacious winter comes a different set of discomforts and inconveniences — the pollens released by trees and grasses every spring. “Spring and fall are the two main allergy seasons in New York — when the trees and grasses release a huge amount of pollen,” says Mauli Desai, MD, an assistant professor of medicine in the Division of Allergy and Clinical Immunology at The Mount Sinai Hospital. “If you’ve had spring allergies in the past, now is the time to prepare, before the pollen count mounts and allergy season goes into full swing.” - Dr. Mauli Desai, Assistant Professor, Medicine, Clinical Immunology, Icahn School of Medicine at Mount Sinai Learn more: http://www.nydailynews.com/life-style/health/spring-start-allergy-season-dr-mauli-desai- article-1.2152281 Additional Coverage: The Science Times: http://www.sciencetimes.com/articles/4654/20150322/tips-to-reduce-your-allergic- reactions-this-season.htm

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: [email protected] on behalf of Lindo, Allisa Subject: Mount Sinai In The News - March 20, 2015 Date: Friday, March 20, 2015 12:08:21 PM Attachments: ATT00001.txt

In the News March 20, 2015

The New York Times – March 20 Biogen Reports Its Alzheimer’s Drug Sharply Slowed Cognitive Decline – Andrew Pollack An experimental drug for Alzheimer’s disease sharply slowed the decline in mental function in a small clinical trial, researchers reported Friday, reviving hopes for an approach to therapy that until now has experienced repeated failures. “It’s certainly encouraging,” said Samuel Gandy, MD, director of the Center for Cognitive Health at The Mount Sinai Hospital in New York, who was not involved in the study. He said the effect of the highest dose was “pretty impressive.” The drug, called aducanumab, appears to have met or exceeded Wall Street expectations in terms of how much the highest dose slowed cognitive decline. - Dr. Samuel Gandy, Professor, Neurology, Psychiatry, Icahn School of Medicine at Mount Sinai, Associate Director, Mount Sinai Alzheimer’s Disease Research Center Learn more: http://www.nytimes.com/2015/03/21/business/alzheimers-drug-trial-shows-cognitive-decline-sharply-slowed.html?_r=1

Forbes – March 20 Biogen Drug Could Inspire New Hope for Alzheimer's Treatments – Matthew Herper An experimental Alzheimer’s treatment being developed by biotechnology firm Biogen Idec BIIB +6.66% seemed to slow patients’ inexorable cognitive decline in a small, preliminary study. The result will probably lead to greater hope for a new strategy for drug companies: Treat Alzheimer’s patients early, when the disease is mild, and use brain imaging to make sure that every patient already has the amyloid plaques that help cause the disease. The data are “convincingly encouraging,” says Samuel Gandy, MD, an Alzheimer’s researcher at the Icahn School of Medicine at Mount Sinai who has been skeptical of medicines that, like BIIB037, are purported to work by clearing plaques of the protein amyloid from the brain. “I’m willing to suspend disbelief.” - Dr. Samuel Gandy, Professor, Neurology, Psychiatry, Icahn School of Medicine at Mount Sinai, Associate Director, Mount Sinai Alzheimer’s Disease Research Center Learn more: http://www.forbes.com/sites/matthewherper/2015/03/20/biogen-drug-could-inspire-new-hope-for-alzheimers-treatments/

Genome Web – March 19 Mount Sinai Explores Ways to Make Genetic Information Part of Asthma Health Study – Uduak Grace Thomas As part of their efforts to analyze and use data collected by a newly launched Asthma Health application, researchers from the Icahn School of Medicine at Mount Sinai are starting to explore ways of incorporating genetic information into the app and making it available to patients and their physicians. The Mount Sinai team developed the asthma app in collaboration with LifeMap Solutions, a BioTime subsidiary. The partners are now developing an electronic genetic counseling platform, which could be included in future versions of the app, that would provide patients with a sort of first line of counseling and information related to genetic tests that they might undergo, Eric Schadt, PhD, director of the Icahn Institute and chair of Icahn School of Medicine at Mount Sinai’s department of genetics and genomic sciences, told GenomeWeb. -Eric Schadt, PhD, Jean C. and James W. Crystal Professor of Genomics, Chair, Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, Director, Icahn Institute for Genomics and Multiscale Biology Learn more: https://www.genomeweb.com/informatics/mt-sinai-explores-ways-make-genetic-information-part-asthma-health-study

Advance for Nurses – March 19 Patient-Centered Environment – Danielle Bullen “Organizations around the country are working to create a patient-centered environment.” So said Sandy Myerson, MBA, MS, BSN, RN. Myerson is one of a growing number of executives who occupy the role of chief patient experience officer, a position she has held at the seven-hospital Mount Sinai Health System in New York since November 2014. This role “ensures a seat at that table for the voice of the customer to be heard and acted on when senior leaders gather and make decisions.” - Sandra Myerson, MBA, MS, BSN, RN, Senior Vice President, Chief Patient Experience Office, Mount Sinai Health System Learn more: http://nursing.advanceweb.com/ebook/magazine.aspx?EBK=NW031615#

Nature Medicine – March 5 Copy Number Variations' Effect on Drug Response Still Overlooked – Cassandra Willyard People vary widely in how they respond to medications, in part because of differences in their genetic makeup. Decades of research have helped untangle how slight variations in our DNA have this effect, fostering the advent of 'pharmacogenetics.' The consequences of CNVs in other genes is less clear, in part because pharmacogenomic researchers haven't devoted as much effort to studying these structural variations as they have to assessing the impact of base changes known as single-nucleotide polymorphisms (SNPs). Even whole-genome sequencing techniques can't provide accurate copy number data—at least not yet. “Sequencing technology has really blossomed in the last few years,” says Stuart Scott, PhD, who studies pharmacogenomics at the Icahn School of Medicine at Mount Sinai in New York. “The ability to infer copy number from next-generation sequencing is going to completely change.” - Stuart Scott, PhD, Assistant Professor, Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai Learn more: http://www.nature.com/nm/journal/v21/n3/full/nm0315-206.html

HealthDay – March 19 'Ground Zero' Workers at Risk of Autoimmune Diseases: Study – Amy Norton Recovery workers who toiled at the World Trade Center disaster site may face a heightened risk of rheumatoid arthritis and similar autoimmune diseases, a new study suggests. The findings, reported online March 16 in the journal Arthritis & Rheumatology, add to the list of potential health effects seen among responders to the Sept. 11, 2001, attacks in New York City. Michael Crane, MD, directs the World Trade Center Health Program at The Mount Sinai Hospital in New York City, which offers free health monitoring and treatment to eligible Ground Zero workers and volunteers. He said the center has seen cases of autoimmune disease "here and there." The new study, he noted, sheds light on the bigger picture: While the conditions are uncommon, recovery workers with the most intense exposure are at relatively greater risk. - Dr. Michael Crane, Assistant Professor, Preventive Medicine, Icahn School of Medicine at Mount Sinai, Medical Director, the World Trade Center Health Program at Mount Sinai, the Mount Sinai Hospital Learn more: http://consumer.healthday.com/senior-citizen-information-31/misc-arthritis-news-41/ground-zero-workers-at-risk-of- autoimmune-diseases-study-697581.html Additional Coverage: U.S. News & World Report: http://health.usnews.com/health-news/articles/2015/03/19/ground-zero-workers-at-risk-of-autoimmune- diseases-study Philly.com: http://www.philly.com/philly/health/HealthDay697581_20150319__Ground_Zero__Workers_at_Risk_of_Autoimmune_Diseases__Study.html

The Guardian – March 19 Is Love Blind? We Went Speed-Dating Blindfolded To Find Out – Nicky Woolf In a glass box in midtown Manhattan decorated with leafy artificial archways, Astroturf and lawn tables, I place my hand on a stranger’s face. I do not know her name. The woman is blindfolded too. Her hand strokes my hair. I am at a blindfold speed-dating event, billed by the organisers – London-based events company Guerilla Science – as a “sensory exploration of dating”. Heather Berlin, PhD, is a neuroscientist who teaches at the Icahn School of Medicine at Mount Sinai and was at the event to lend some scientific credibility. Between each round, she gave a little talk about the science behind each sense. “The idea is that much of the processing in the brain is going on unconsciously, dictating the decisions we make,” she tells me later. “So you can go through each sensory domain and talk about the various factors making someone attractive.” -Heather Berlin, PhD, Assistant Professor, Psychiatry, Neuroscience, Icahn School of Medicine at Mount Sinai Learn more: http://www.theguardian.com/lifeandstyle/2015/mar/19/speed-dating-event-blindfold

Bio IT World – March 19 The Right Drug the First Time – Aaron Krol Aniwaa Owusu Obeng, PharmD, is a pharmacist at the Icahn School of Medicine at Mount Sinai in New York, where results from a few pharmacogenetic tests are automatically reported to physicians through the EMR. She says that physicians’ demands for these alerts are stringent: “Show it to me as something I can read in less than 30 seconds and make a decision.” That doesn’t leave much room for nuance when a center decides it’s time to implement a new test. However many variables have to be juggled behind the scenes, the results have to be a clear-cut recommendation: prescribe a drug, avoid it, or adjust the dose. - Aniwaa Owusu Obeng, PharmD, Assistant Professor, Medicine, General Internal Medicine, Icahn School of Medicine at Mount Sinai Learn more: http://www.bio-itworld.com/2015/3/19/right-drug-first-time.html

Time Warner Cable – March 20 Fall Prevention Helps Keep the Elderly from Bigger Health Problems – Kristen Shaughnessy With two grandmothers who each celebrated their 100th birthday, you see the changes that come with aging. You also learn that one of the things people worry about most is falling, because of all the complications that could result. Therefore, we went to the experts. "Having a fall puts you at increased risk of ending up in a nursing home, increased risk of something serious like a hip fracture and once someone has a hip fracture it tends to start a cascade of disabilities," says Audrey Chung, MD, Director of Martha Stewart Center for Living at The Mount Sinai Hospital. "Some of the statistics say that 50 percent of people over the age of 80 will fall in their lifetime and very often those people are multiple fallers, which means they have a fall after fall after fall," says Eileen Callahan, MD, of The Mount Sinai Hospital. - Dr. Audrey Chun, Associate Professor, Geriatrics and Palliative Care, Medicine, Icahn School of Medicine at Mount Sinai, Director, the Martha Stewart Center for Living at Mount Sinai - Dr. Eileen Callahan, Associate Professor, Geriatrics and Palliative Care, Medicine, Icahn School of Medicine at Mount Sinai Learn more: http://www.twcnews.com/nys/buffalo/healthy-living/2015/03/19/fall-prevention-helps-keep-the-elderly-from-bigger-health- problems.html

The Jewish Chronicle – March 19 Feeling panicked? It could be in the genes – Deborah Kotz Life experiences are capable of shaping perceptions and reactions even without touching DNA. In studies published over the past decade, Rachel Yehuda, PhD, a professor of psychiatry and neuroscience at the Icahn School of Medicine at Mount Sinai Hospital in New York has found that children of Holocaust survivors have altered stress response systems and differences in methylation on the gene that regulates the number of stress hormone receptors. “We certainly know that human experiences affect how our genes are expressed,” said Yehuda, who has performed epigenetic studies on Holocaust survivors. “But we don’t know for sure how this process works and how strong a contributor epigenetics really is compared to other things like genes.” - Rachel Yehuda, PhD, Professor, Psychiatry, Neuroscience, Director, the Traumatic Stress Studies Division, Icahn School of Medicine at Mount Sinai, Director, Mental Health Patient Care Center and PTSD Research Program, the James J. Peters Veterans Affairs Medical Center in the Bronx Learn more: http://thejewishchronicle.net/view/full_story/26529345/article-Feeling-panicked--It-could-be-in-the-genes? instance=secondary_stories_left_column

WebMD – March 17 How Often Do I Need to Shampoo? First off, the basics: what does shampoo do? Shampoo traps oils, so if you do it too frequently, you may dry your hair out, leaving it prone to breakage, says Angela Lamb, MD, an assistant professor of dermatology at the Icahn School of Medicine at Mount Sinai in New York City. “Hair produces natural oil called sebum, and shampoo is an emulsifier that captures and traps excess oil, dirt, and product residue, which you then rinse out to clean the hair,” Lamb says. For the most part, some dirt is OK and natural -- and you definitely want some oils to remain in your hair. - Dr. Angela Lamb, Assistant Professor, Dermatology, Icahn School of Medicine at Mount Sinai, Director, Westside Mount Sinai Dermatology Practice Faculty Practice Learn more: http://www.webmd.com/beauty/hair-styling/how-often-need-shampoo

Yahoo Mujer – March 19 Smiles Without Penalty: Say 'Goodbye' To Tartar on Your Teeth – Raúl Rodríguez Follow these recommendations to smile showing off a beautiful white smile tartar free. Change your brush . Do not get too attached to your toothbrush. It is advisable to change it every three months, since worn bristles do not clean your teeth well, as revealed to Yahoo by John L. Pfail, DDS, the chair of the Department of Dentistry at The Mount Sinai Hospital in New York. - Dr. John Pfail, Assistant Professor, Dentistry, Icahn School of Medicine at Mount Sinai, Chair, Department of Dentistry, The Mount Sinai Hospital Learn more: https://es-us.mujer.yahoo.com/fotos/adios-sarro-en-dientes-1426778267-slideshow/adios-al-sarro-en-tus-dientes-photo- 1426778117502.html [Article is in Spanish]

Queens Chronicle – March 19 Skin Cancer Prevention – Adekemi Akingboye, MD, FAAD The incidence of skin cancer is on the rise around the globe. It is important for people to understand what activities put them at higher risk and what, if any, familial predispositions they may have, as well as what can be done to prevent morbidity and mortality from these cancers. There are various types of skin cancers, the most common being basal cell carcinoma followed by squamous cell carcinoma. - Dr. Adekemi Akingboye, Instructor, Dermatology, Icahn School of Medicine at Mount Sinai Learn more: http://issuu.com/queenschronicle/docs/south_03-19-15small/29?e=3006990/11930317

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: [email protected] on behalf of MountSinaiNewsNow Subject: Mount Sinai In The News - March 18, 2015 Date: Wednesday, March 18, 2015 11:27:33 AM Attachments: ATT00001.txt

In the News March 18, 2015

The New York Times – March 17 Breast Biopsies Leave Room for Doubt, Study Finds – Denise Grady Breast biopsies are good at telling the difference between healthy tissue and cancer, but less reliable for identifying more subtle abnormalities, a new study finds. The new findings, reported Tuesday in JAMA, challenge the common belief that a biopsy is the gold standard and will resolve any questions that might arise from an unclear mammogram or ultrasound. A surgeon not involved with the study, Elisa Port, MD, a co-director of the Dubin Breast Center and the chief of breast surgery at The Mount Sinai Hospital in Manhattan, said the research underlined how important it is that biopsies be interpreted by highly experienced pathologists who specialize in breast disease. “As a surgeon, I only know what to do based on the guidance of my pathologist,” Dr. Port said. “Those people behind the scenes are actually the ones who dictate care.” - Dr. Elisa Port, Associate Professor, Surgery, Icahn School of Medicine at Mount Sinai, Chief, Breast Surgery, Co-Director, Dubin Breast Center, The Mount Sinai Hospital Learn more: http://www.nytimes.com/2015/03/18/health/breast-biopsies-dcis-atypia-diagnosis-leave- room-for-doubt.html?em_pos=small&emc=edit_hh_20150317&nl=subscription- 3&nlid=65469617&ref=headline&_r=1&referrer= Additional Coverage: The Boston Globe via The New York Times: https://www.bostonglobe.com/news/science/2015/03/17/breast-biopsies-leave-room-for-doubt-study- finds/3raI3sB2jVdYL8EHFFuBGN/story.html Sarasota Herald-Tribune via The New York Times: http://health.heraldtribune.com/2015/03/18/breast- biopsies-leave-room-for-doubt/

Health Aim – March 18 Love Map Found In the Brain – Rubelle Tan Scientists have found a way to map the brain’s activity when one is in love: the love map. Researchers from New York and China have worked on this research together to note brain activities of when a person is in love, and most of these activities are connected with motivation and reward. The study, “Love-related Changes In The Brain: A Resting State Functional Magnetic Resonance Imaging Study”, has obtained the “first empirical evidence of love-related alterations in brain functional architecture,” notes the researchers. Led by Professor Xiaochu Zhang, a team from the University of Science and Technology of China in Hefei, worked with colleagues at the Southwest University in Chongqing and the Icahn School of Medicine at Mount Sinai in New York. - Icahn School of Medicine at Mount Sinai Learn more: http://www.healthaim.com/love-map-found-brain/17362 Additional Coverage: Xataka.com: http://www.xataka.com/otros/el-amor-esta-en-el-aire-y-en-el-escaner [Article is in Spanish]

Yahoo via Good Morning America – March 17 Michigan Couple Gets Quite a Surprise When They Meet Their New Baby – Liz Neporent A Michigan couple told they were having a girl got the shock of their life when surprise ... it was a boy! Danielle Williams had a sonogram back in October 2014, 20 weeks into her pregnancy, her husband told ABC News. The technician informed them they would be adding a second daughter to their family and they were thrilled. “When the doctor poked his head up and finally announced it was a boy, she thought it was a joke,” he said. In her 35 years as a practicing OB/GYN, she has never seen a mistake like this with one of her patients, said Laura Corio, MD, a gynecologist with The Mount Sinai Hospital in New York. “The technology is so good nowadays you can really see the baby -- especially if it’s a boy” she said. - Dr. Laura Corio, Assistant Clinical Professor, Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai Learn more: https://gma.yahoo.com/california-couple-gets-quite-surprise-meet-baby-175741992--abc- news-health.html

Prevention – March 16 7 Ways to Get Younger-Looking Knees and Elbows – Krista Bennett DeMaio Anti-aging creams for your eyes and neck are now standard issue, but when it comes to looking younger, there are two often-ignored spots further south that could use a little TLC: your elbows and knees. These joints (and the skin around them) are quick to show the signs of time with dryness, wrinkling, and sagging. Constant friction or pressure on your joints—leaning your elbows on your desk as you type, performing gym exercises on your knees—causes low-grade inflammation that triggers hyperpigmentation, explains Joshua Zeichner, MD, director of cosmetic and clinical research in dermatology at The Mount Sinai Hospital's Department of Dermatology in New York City. The result: a dark, shadowy look that’s far from youthful. "It's more noticeable in patients in their 40s and beyond, because discoloration takes a while to build up," says Zeichner. - Dr. Joshua Zeichner, Assistant Professor, Dermatology, Icahn School of Medicine at Mount Sinai, Director, Cosmetic and Clinical Research in Dermatology, The Mount Sinai Hospital Learn more: http://www.prevention.com/beauty/younger-looking-knees-and-elbows

The New York Daily News – March 18 What Is Iboga? Psychedelic Drug Scott Disick Will Take at Rehab Isn't Cure-All for Addiction, Say Experts – Meredith Engel Scott Disick is getting high to beat his addictions. The Costa Rican rehab that the 31-year-old reality star has called home since early this week specializes in treatment using the iboga plant, a hallucinatory African rainforest shrub. The plant-based hallucinogen hasn’t been studied enough to merit a sterling reputation, says Harris Stratyner, PhD, a psychiatrist at The Mount Sinai Hospital and vice president of Caron Treatment Centers. “To put somebody in a psychedelic dream state, I just have difficulty doing that until things are studied,” he told The News. “If this is such a miracle psychedelic, how come it isn't the big cure all over the (world)?” - Harris Stratyner, PhD, Associate Clinical Professor, Psychiatry, Icahn School of Medicine at Mount Sinai Learn more: http://www.nydailynews.com/life-style/health/iboga-scott-disick-new-pyschedelic-article- 1.2153558

WCBS TV – March 17 Glasses Meant To Improve Focus Claim to Provide a Window to Our Brains Wearable technology lets us track the steps we take, the good we eat and even how we sleep. Now, a new device claims to show us how we think and provides a window to our brain. But there were some doubts. “The question is what are we really measuring with these sensors, and how informative is that information,” Assistant Professor of Psychiatry and Neuroscience at the Icahn School of Medicine at Mount Sinai Heather Berlin said. Berlin questions the effectiveness of the devices, saying sometimes just a simple change in routine or even physical exercise can bring back focus and help brain function. -Heather Berlin, PhD, Assistant Professor, Psychiatry, Neuroscience, Icahn School of Medicine at Mount Sinai Learn more: http://newyork.cbslocal.com/2015/03/17/seen-at-11-glasses-meant-to-improve-focus-claim- to-provide-a-window-to-our-brains/

New Beauty – March 16 Breakouts 101: How to Treat Different Types of Acne – Margaret McGriff From the occasional whitehead to full-on painful pimples, different things cause different types of breakouts. Knowing what they are and how to treat them is half the battle of keeping skin clear and blemish-free. New York dermatologist Gary Goldenberg, MD breaks down the different types of acne and how we can get rid of them. - Dr. Gary Goldenberg, Assistant Professor, Dermatology, Pathology, Icahn School of Medicine at Mount Sinai Learn more: http://www.newbeauty.com/blog/dailybeauty/8470-different-types-of-acne/

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: [email protected] on behalf of Lindo, Allisa Subject: Mount Sinai In The News - March 17, 2015 Date: Tuesday, March 17, 2015 2:38:52 PM Attachments: ATT00001.txt

In the News March 17, 2015

Reuters – March 17 Ablation with Mitral-Valve Surgery Often Fixes Atrial Fibrillation – Gene Emery Performing ablation during mitral valve surgery cuts the incidence of atrial fibrillation by more than half, whether surgeons use pulmonary-vein isolation or the biatrial maze procedure. But ablation surgery also produces a 2.5-fold increase in the likelihood that a patient will end up with a pacemaker, according to a prospective randomized study of 260 volunteers at 20 medical centers in the U.S. and Canada. Roughly 30% to 50% of people who have mitral valve surgery also have atrial fibrillation, making them candidates for ablation. Until now, there was little data to support ablation during valve surgery or to identify which type of surgery might be best. "There is a very high degree of variability in surgical practice," and randomized trials have been difficult to do because "there are very strong preferences both from the treating physicians and patients over whether they want ablation or not," coauthor Annetine C. Gelijns, MD, of the Icahn School of Medicine at Mount Sinai in New York City told Reuters. - Dr. Annetine Gelijns, Edmund A. Guggenheim Professor of Health Policy, Icahn School of Medicine at Mount Sinai, System Chair, Population Health Science and Policy, The Mount Sinai Health System Learn more: No Web Link Available

Good Morning America – March 17 MRI Could Determine How in Love You Truly Are – TJ Holmes Most people think of the heart when they think about love, but it’s really all in your head. New research shows that. A new study is revealing that when you’re in love, your brain looks decidedly different than when you’re not. “When we are in love, we are seeing that the brain looks happier. There is a tiny little region in the brain that’s called the reward center and it’s activated when we are doing things that are very pleasurable,” explains Anna Zilverstand, PhD, of the Icahn School of Medicine at Mount Sinai. -Anna Zilverstand, Postdoctoral Fellow, Psychiatry, Icahn School of Medicine at Mount Sinai Learn more: http://abcnews.go.com/GMA/video/mri-determine-love-29690989

Los Angeles Times – February 13 For Valentine's Day, Draw Brains, Not Hearts – Geoffrey Mohan Forget the heart and Cupid this Valentine's Day. It's the brain that makes you do crazy stuff when you're in love. In fact, love apparently can remodel your brain, according to a study published online Friday in Frontiers in Human Neuroscience. "We found a correlation between brain change and love duration in the love group, and we also found negative correlation between the brain change and the duration since love ended," said study co-author Zhiling Zou, a Southwest University psychologist who is a visiting scholar at the Icahn School of Medicine at Mount Sinai in New York. "So, I think this kind of brain change is love-related.” Plenty of studies appear to support the analysis, said Icahn researcher Federico d'Oleire Uquillas. "We know that falling in love will promote focus and attention on a preferred individual," he said. -Frederico d’Oleire Uquillas, Clinical Research Coordinator, Psychiatry, Neuroscience, Icahn School of Medicine at Mount Sinai - Zhiling Zou, Visiting Scholar, Icahn School of Medicine at Mount Sinai Learn more: http://www.latimes.com/science/sciencenow/la-sci-sn-brain-love-valentine-20150213- story.html Additional Coverage: Psy Post: http://www.psypost.org/2015/03/neuroimaging-study-shows-how-being-in-love-changes-the- architecture-of-your-brain-32330 The Independent (UK): http://www.independent.co.uk/news/science/science-of-love-it-really-is-all-in- the-mind-say-experts-10108781.html National Post: http://news.nationalpost.com/2015/03/16/what-is-love-brain-researchers-use-mri-scans- to-piece-together-romantic-love-map-of-the-human-mind/ International Business Times: http://www.ibtimes.co.uk/brain-activity-very-different-those-love-shows- study-mapping-love-map-1492041

Health Leaders Magazine – March 2015 Oncology Care Options – Tinker Ready Healthcare leaders are weighing evidence and making decision on the value of adopting new cancer services, including low-dose CT scans, high-priced drugs, and efforts to address comorbidities. Randall F. Holcombe, MD, is chief medical officer for cancer at Mount Sinai Health System in New York City. He says by assembling a multidisciplinary team, the organization’s cancer institute can better address aspects of care such as anxiety or comorbidities. - Dr. Randall Holcombe, Professor, Medicine, Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, Director, Clinical Cancer Affairs, The Mount Sinai Hospital, Chief Medical Officer, Cancer, Mount Sinai Health System Learn more: http://www.healthleadersmagazine-digital.com/healthleadersmagazine/march_2015#pg57

The Wall Street Journal – March 16 Mets’ Wheeler Has Elbow Tear, Likely to Miss Season – Jared Diamond In this era of baseball, pitchers are breaking down at an alarming rate. Nobody knows why, at least with any degree of certainty. Nonetheless, by staking their future on the development of their young pitchers, the Mets put their fate on the structural integrity of the human elbow. Johnny Arnouk, MD, an orthopedic surgeon at Mount Sinai Beth Israel in Manhattan, suggested that many pitchers enter the league with damaged elbows. He said that studies into this topic show that arm fatigue contributes to ligament vulnerability and youth players today throw more often while fatigued than ever before. - Dr. Johnny Arnouk, Sports Medicine Specialist, Orthopaedist, Mount Sinai Beth Israel Learn more: http://www.wsj.com/articles/mets-wheeler-has-a-torn-ulnar-collateral-ligament-1426516471

Crain’s Health Pulse – March 17 Sinai's Baby Boom The Mount Sinai Hospital filed a certificate-of-need application this month to expand its neonatal intensive-care unit. The hospital aims to convert 11 medical/surgical beds to NICU beds at a cost of $14.8 million, to be funded with cash. Use of Mount Sinai's NICU grew 12.2% over a four-year period, with 725 NICU discharges in 2014, according to the application. The hospital expects that growth to continue as the population in its immediate area continues to rise. "The expanded NICU will be approximately 15,130 square feet, including 10 private patient rooms, 36 open-suite positions, a procedure room, a lactation suite, waiting rooms, a family center and appropriate support space," the application reads. -The Mount Sinai Hospital Learn more: http://www.crainsnewyork.com/article/20150317/PULSE/150319882/new-nursing-school-at- north-shore-lij-hofstra

HealthDay – March 16 Age-Linked Memory Loss May Be Worse for Men, Study Finds – Amy Norton A new study finds that nearly everyone will suffer more memory lapses as they age, with men being more vulnerable to failing memory than women. The study also reported that people's memory skills and brain volume typically decline with age -- and, surprisingly, it seems to have little to do with the buildup of brain "plaques" that mark Alzheimer's disease, the study suggests. Mary Sano, PhD, an Alzheimer's researcher at The Mount Sinai Hospital, in New York City, said the findings are "exciting." A lot of research aimed at preventing Alzheimer's has focused on amyloid buildup, Sano noted. But this study, she said, suggests other avenues -- including "interventions that focus on brain volume" -- should be explored, too. And how do you change brain volume? Exercise is one possibility. "Research has shown that physical activity may slow the brain volume loss that comes with aging," Sano said. -Mary Sano, PhD, Professor, Psychiatry, Associate Dean for Clinical Research, Director of Alzheimer’s Disease Research, Icahn School of Medicine at Mount Sinai Learn more: http://consumer.healthday.com/cognitive-health-information-26/alzheimer-s-news-20/age- linked-memory-loss-may-be-worse-for-men-study-finds-697458.html Additional Coverage: Philly.com: http://www.philly.com/philly/health/topics/HealthDay697458_20150316_Age- Linked_Memory_Loss_May_Be_Worse_for_Men__Study_Finds.html

HealthDay – March 16 Vitamin D Won't Help Fight High Blood Pressure, Researchers Say – Randy Dotinga Vitamin D may help the body in many ways, but a new data review suggests it won't do much to lower high blood pressure. Reporting March 16 in the journal JAMA Internal Medicine, researchers found no sign that boosting vitamin D levels had any effect on either the upper or lower numbers in a blood pressure reading. An expert in the United States said studies like these are important. "Health claims related to vitamins and nutritional supplements need to be validated in prospective, randomized clinical trials," said Robert Rosenson, MD, director of the Cardiometabolic Unit at The Mount Sinai Hospital in New York City. "Currently, there is a false public perception that certain vitamins or supplement therapies work...costing the public unnecessary costs, without the necessary scientific evidence supporting their health claims," he said. - Dr. Robert Rosenson, Professor, Medicine, Cardiology, Icahn School of Medicine at Mount Sinai, Director, Cardiometabolic Unit, The Mount Sinai Hospital Learn more: http://consumer.healthday.com/cardiovascular-health-information-20/heart-attack-news- 357/vitamin-d-won-t-help-fight-high-blood-pressure-study-697405.html

The Nation (New Zealand) – March 14 Fighting Fat – Tackling NZ’s Obesity Epidemic – Lucy Warhurst As New Zealand heads towards becoming the fattest nation in the world in five years, a growing number of experts are suggesting that diet and exercise isn’t the cure. For 30 years, we have been told to go on diets to lose weight, exercise more, eat less, and you can look fit. But in that time, obesity levels have soared. And now experts say we are wasting our time. Diet and exercise don’t work, or at least not how we thought. “That might be enough for prevention but at the point that somebody has had sustained obesity, that’s no longer going to cut it,” says Christopher Ochner, PhD, of the Icahn School of Medicine at Mount Sinai in New York. Ochner is an obesity and nutrition expert and believes that obesity is a biological disease. -Christopher Ochner, PhD, Assistant Professor, Pediatrics, Adolescent Medicine, Psychiatry, Icahn School of Medicine at Mount Sinai Learn more: http://www.3news.co.nz/tvshows/thenation/fighting-fat--tackling-nzs-obesity-epidemic- 2015031410#axzz3UUepI2Q9

Healthline News – March 10 Type 2 Diabetes Less Common in Patients with High-Cholesterol Disorder – Kristen Fischer A new study has found that people with familial hypercholesterolemia have a lower likelihood of having type 2 diabetes compared to their relatives who do not have the disorder. Gerald Bernstein, MD, the director of the diabetes management program at Mount Sinai Beth Israel in New York City, says the difference is significant. But, he asks, what causes it? “It could be parallel genetic defects not related by physiology,” he said. “Or it could mean that the genetic disorder in some way affects how the insulin- producing cells work, or some other point in the pathway from insulin production to insulin action.” -Dr. Gerald Bernstein, Associate Clinical Professor, Medicine, Endocrinology, Diabetes and Bone Disease, Icahn School of Medicine at Mount Sinai, Director, Diabetes Management Program, Mount Sinai Beth Israel Learn more: http://www.healthline.com/health-news/type-2-diabetes-less-common-in-patients-with- high-cholesterol-disorder

Medpage Today – March 16 REGULATE-PCI: Roxana Mehran, MD “Of course it’s disappointing when a trial is stopped early and you have so much hope for this novel anti-coagulant that we had, but I’m honored to be able to present it,” says Roxana Mehran, MD, of the Icahn School of Medicine at Mount Sinai. She is discussing a randomized, open-label, multi-center, active-controlled, parallel group study to determine the efficacy and safety of the reg1 anticoagulation system compared to bivalirudin in patients undergoing Percutaneous Coronary Intervention (REGULATE-PCI). - Dr. Roxana Mehran, Professor, Medicine, Cardiology, Population Health Science and Policy, Icahn School of Medicine at Mount Sinai Learn more: http://www.medpagetoday.com/ACC2015VideoOnTheScene/Cardiology/ACC-Videos/1054

Time Warner Cable Noticias – March 12 Colonoscopy Key to Preventing Colon Cancer – Luz Plasencia Are you over 50 or have a history of colon cancer in your family? If your answer is yes and have not had a colonoscopy, do not wait. It is one of the cancers that can be prevented, yet more than 1,500 people die annually in the city from colorectal cancer. "Colon cancer is detected in more than 10,000 Hispanic men and women each year in the United States. In the US it is the second leading cause of cancer death in men and women," said Susana González, MD, of The Mount Sinai Hospital. - Dr. Susana Gonzalez, Assistant Professor, Medicine, Gastroenterology, Icahn School of Medicine at Mount Sinai Learn more: http://www.ny1noticias.com/nyc/twc-ny1-noticias/salud/2015/03/12/colonoscop-a--clave- para-la-prevenci-n-del-c-ncer-de-colon-.html [Article is in Spanish]

WCBS TV – March 16 New Positive Studies on Cholesterol Medication – Max Gomez WCBS TV’s Max Gomez reports on an exciting breakthrough in the fight against cholesterol and heart disease. A new type of drug has been able to lower bad cholesterol levels to unprecedented levels. Donald Smith, MD, was interviewed about ACC 2015 meeting news also published in the New England Journal of Medicine about the benefits of a new type of cholesterol-lowering medications called PCSK9 inhibitors. “They are able to lower LDL down to 60 and that’s a good level to be,” says Dr. Smith about these new drugs. -Dr. Donald Smith, Associate Professor, Medicine, Cardiology, Preventive Medicine, Icahn School of Medicine Learn more: http://newyork.cbslocal.com/video/11238253-dr-max-gomez-new-cholesterol-drug/ Additional Coverage: WLNY: No Web Link Available

Refinery 29 – March 16 Oily Eyelids: How to Stop Them from Effing up Your Makeup Game – Mi-Anne Chan If you have oily eyelids, you know that getting makeup to stay in place is a struggle. Pick the right skin care. After your face is clean, move on to your skin care, but be sure to look at the ingredients in your moisturizers and eye creams. "If the issue is that makeup isn't staying in place, perhaps the problem is using moisturizers that aren't fully absorbing," says Heidi Waldorf, MD, dermatologist at The Mount Sinai Hospital. - Dr. Heidi Waldorf, Associate Clinical Professor, Dermatology, Icahn School of Medicine at Mount Sinai, Director, Laser and Cosmetic Dermatology, The Mount Sinai Hospital Learn more: http://www.refinery29.com/oily-eyelids#slide-2

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: [email protected] on behalf of Lindo, Allisa Subject: Mount Sinai In The News - March 16, 2015 Date: Monday, March 16, 2015 10:55:29 AM Attachments: ATT00001.txt

In the News March 16, 2015

FoxNews.com – March 13 Asthma Health App Harnesses the Power of Apple’s iPhone – James Rogers A new app developed by the Icahn School of Medicine at Mount Sinai in New York and LifeMap Solutions aims to revolutionize asthma research by harnessing the power of Apple’s iPhone. The Asthma Health app was one of a number of medical research apps unveiled during Apple's “Spring Forward” event on Monday. Using the tech giant's new ResearchKit open source software framework, the app aims to make it easy for asthma sufferers to participate in research studies via their iPhones. “In order to get a handle on these complex diseases like asthma, you need to engage with a much larger population than you would have to in a classic research study,” Eric Schadt, PhD, professor of genomics at the Icahn School of Medicine told FoxNews.com. -Eric Schadt, PhD, Jean C. and James W. Crystal Professor of Genomics, Chair, Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, Director, Icahn Institute for Genomics and Multiscale Biology Learn more: http://www.foxnews.com/tech/2015/03/13/asthma-health-app-harnesses-power-apples- iphone/

The Science Times – March 13 Psychoactive Ayahuasca Plant Might Be the Key to Reversing Diabetes – Nabil Ansari A plant named Ayahuasca contains the chemicals that can be potentially used to regenerate lost pancreatic cells, which would then reverse diabetes. According to a recent research published in the Nature Medicine, this new discovery can help us successfully reverse diabetes. Beta cells are the ones that work in small clusters called the islets that help produce insulin necessary to keep your body's blood sugar levels in check. Andrew Stewart, the director of the Diabetes, Obesity and Metabolism Institute at the Icahn School of Medicine at Mount Sinai, New York City says, "In children and adults with type 1 diabetes, they have lost 99 percent of their beta cells, so they cannot make enough insulin. That's the cause of their diabetes." - Dr. Andrew Stewart, Professor, Medicine, Endocrinology, Diabetes and Bone Disease, Director, Diabetes, Obesity and Metabolism Institute, Icahn School of Medicine at Mount Sinai Learn more: http://www.sciencetimes.com/articles/4211/20150313/psychoactive-ayahuasca-plant-might- be-the-key-to-reversing-diabetes.htm

KOIN TV – March 13 Newfoundlands Help Patients Smile through Chemo – Jennifer Hoff To dog lovers, it’s a no brainer – canine companions bring a lot of comfort. But for the first time, a study has proven the effects of therapy dogs. Researchers at Mount Sinai Beth Israel conducted a study and found that patients receiving intensive radiation therapy for gastrointestinal, head or neck cancers, experienced increases in emotional well-being and quality of life when they received visits from a certified therapy dog during the course of their treatment. “This study is the first such definitive study in cancer and it highlights the merits of animal-assisted visits using the same scientific standards as we hold for the cancer treatment itself,” said Stewart B. Fleishman, MD, principal investigator and Founding Director of Cancer Supportive Services at Mount Sinai Beth Israel. - Dr. Stewart Fleishman, Founding Director, Cancer Supportive Services, Mount Sinai Beth Israel Learn more: http://koin.com/2015/03/13/newfoundlands-help-patients-smile-through-chemo/

Medpage Today – March 14 CTA No Better Than Stress Test for Coronary Disease – Shara Yurkiewicz Patients with symptoms of coronary artery disease (CAD) who underwent coronary computed tomographic angiography (CTA) did not have better clinical outcomes than those who had functional testing. The findings were reported at a late-breaking clinical trial session at the American College of Cardiology meeting and were also published at the same time in the New England Journal of Medicine. The findings were interpreted by a panel of discussants as a reason to consider CTA over functional testing. Both modalities have the same efficacy and same cost, said discussant Valentin Fuster, MD, the director of Mount Sinai Heart in New York City and current editor-in-chief of the Journal of the American College of Cardiology, in a press briefing here. - Dr. Valentin Fuster, Professor, Medicine, Cardiology, Icahn School of Medicine at Mount Sinai, Director, Mount Sinai Heart, the Zena and Michael A. Wiener Cardiovascular Institute, the Marie-Josée and Henry R. Kravis Center for Cardiovascular Health Learn more: http://www.medpagetoday.com/Cardiology/AcuteCoronarySyndrome/50483

The Dr. Oz Show – March 9 Cardiac Arrest Patient Chris LaPak Shares his Miraculous Survival Story – Mehmet Oz Chris Lapak explains how his heart stopped beating for 13 minutes while he was underwater and in the midst of completing the NYC Triathlon. His doctors Eyal Herzog, MD, and Sandhya Balaram, MD joined him for his appearance on The Dr. Oz Show to tell the world his survival story and how quick emergency response and advanced cooling therapy available at Mount Sinai St. Luke’s helped him beat the odds and save his life. -Dr. Eyal Herzog, Director, Cardiac Care Unit, Mount Sinai St. Luke’s - Dr. Sandhya Balaram, Cardiothoracic Surgeon, Mount Sinai St. Luke’s Learn more: http://www.doctoroz.com/episode/i-shouldn-t-be-alive-amazing-stories-survival? video_id=4100870112001

OncLive – March 14 Richard Stock, MD, on Brachytherapy for Prostate Cancer Richard Stock, MD, a professor of radiation oncology at the Icahn School of Medicine at Mount Sinai Hospital, talks about brachytherapy and its benefits for patients with prostate cancer. Brachytherapy, which involves placing radioactive pellets in or near the tumor, limits the dose of radiation only to the prostate by delivering a low dose from within the body over several months. The prostate receives a high amount of radiation therapy biologically, while keeping the radiation dose to the rectal and bladder very low. - Dr. Richard Stock, Clinical Professor, Radiation Oncology, Icahn School of Medicine at Mount Sinai Learn more: http://www.onclive.com/conference-coverage/ipcc-2015/Dr-Richard-Stock-on- Brachytherapy-for-Prostate-Cancer

Newsworks.org – March 12 Chronic Fatigue Syndrome Gets New Name, Enhanced Recognition – Elana Gordon The name, systemic exertion intolerance disease, may be new but the disease itself isn't. Formerly called, Chronic Fatigue Syndrome, the condition is mysterious and complex. It has stumped the medical system for centuries. There's no test for it, which sufferers say, along with its current name, makes the condition easy to dismiss. "That's the purpose, to make it easier for the doctor to diagnose and take it seriously," says Benjamin Natelson, MD, a professor of neurology at Icahn School of Medicine at Mount Sinai who also served on the panel and who served on the 1994 committee that shaped its most recent definition. He says that's important because so often, when doctors can't diagnose something with a test, they don't know what it could be and tell patients "it's all in their heads." - Dr. Benjamin Natelson, Professor, Neurology, Icahn School of Medicine at Mount Sinai Learn more: http://www.newsworks.org/index.php/local/the-pulse/79344-chronic-fatigue-syndrome- gets-new-name-enhanced-recognition

Cosmopolitan – March 15 Here Are the Secrets to Treating All of Your Breakouts – Gina Way Repeat breakouts can seem like a mystery. In the search for answers, Western derms— armed with their prescription pads—are increasingly taking a holistic approach. "We're reading the skin for clues about what's going on inside the body," explains Ellen Marmur, MD, founder of Marmur Medical and associate clinical professor of dermatology at the Icahn School of Medicine at Mount Sinai. "Hair that rests on your skin is a prime pimple-maker because the silicones and oils in hair products clog the pores," says Cybele Fishman, MD, integrative dermatologist and also an assistant clinical professor of dermatology at Icahn School of Medicine at Mount Sinai. -Dr. Ellen Marmur, Associate Clinical Professor, Dermatology, Icahn School of Medicine at Mount Sinai -Dr. Cybele Fishman, Assistant Clinical Professor, Dermatology, Icahn School of Medicine at Mount Sinai Learn more: http://www.cosmopolitan.com/style-beauty/a37570/acne-treatment-breakout-secrets/

The New York Daily News – March 15 Daily Checkup: March is Multiple Sclerosis Month, so Pay Attention to Your Health – Katie Charles An estimated 2.5 million people around world are living with multiple sclerosis including Montel Williams, Jack Osbourne and Ann Romney. “Multiple sclerosis, or MS for short, is an autoimmune disease that causes the body to attack the central nervous system, especially the brain and spinal cord,” says Fred Lublin, MD, the director of the Corinne Goldsmith Dickinson Center for Multiple Sclerosis at The Mount Sinai Hospital. “Genetics and environmental factors both play a role, and some people are more likely to develop MS than others.” Hundreds of thousands of Americans have been diagnosed with MS. “It’s a disease that is not uncommon — in New York City, there are about 200 cases of MS per 100,000 individuals,” -Dr. Fred Lublin, Saunders Family Professor of Neurology, Director, the Corinne Goldsmith Dickinson Center for Multiple Sclerosis at The Mount Sinai Hospital Learn more: http://www.nydailynews.com/life-style/health/daily-checkup-march-multiple-sclerosis- mont-article-1.2143090

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: [email protected] on behalf of Lindo, Allisa Subject: Mount Sinai In The News - March 13, 2015 Date: Friday, March 13, 2015 11:30:17 AM Attachments: ATT00001.txt

In the News March 13, 2015

Wareable – March 11 Apple Researchkit: Everything You Need to Know about the Medical Research Platform – Stephanie Charara There's nothing better at solving small, day-to-day, First World problems than an Apple device. Apple has decided to tap into this potential to bring medical research into the 21st century with its new ResearchKit software platform. With user-friendly ResearchKit apps, anyone with an iPhone will be able to opt into medical studies relating to their health conditions saving institutions time and money. It also provides access to people who have never completed medical studies because of where they live, for instance. "By using Apple's new ResearchKit framework, we're able to extend participation beyond our local community and capture significantly more data to help us understand how asthma works," said Eric Schadt, MD, Professor of Genomics at the Icahn School of Medicine at Mount Sinai. -Eric Schadt, PhD, Jean C. and James W. Crystal Professor of Genomics, Chair, Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, Director, Icahn Institute for Genomics and Multiscale Biology Learn more: http://www.wareable.com/saves-the-day/what-is-apple-researchkit-iphone-watch- everything-you-need-to-know-931 Additional Coverage: Deutsche Gesundheits Nachrichte (Germany): http://www.deutsche-gesundheits- nachrichten.de/2015/03/13/apple-laesst-nutzer-per-app-an-medizinischen-studien-teilnehmen/ [Article is in German]

Modern Healthcare – March 11 Apple's ResearchKit Draws Massive Interest (and Some Reservations) – Sabriya Rice A new crop of mobile apps built with Apple's new ResearchKit framework are moving fast into medical research. Apple announced ResearchKit Monday during an event that also revealed new details about the much-hyped Apple Watch. The company described ResearchKit as an open-source software framework that will allow physicians and scientists to collect and monitor medical data from patients using iPhones. The University of Rochester Medical Center and the Icahn School of Medicine at Mount Sinai, New York, are also already taking advantage of the new Apple technology. Using it, they say, will lead to greater understanding of the impact disease has on patients' lives. “This is definitely a new era,” said Yvonne Chan, MD, director of personalized medicine and digital health at Mount Sinai. - Dr. Yvonne Chan, Assistant Professor, Genetics and Genomic Sciences, Emergency Medicine, Director, Personalized Medicine and Digital Health, Icahn School of Medicine at Mount Sinai - Dr. Jeffrey Silverstein, Professor, Anesthesiology, Geriatrics and Palliative Care, Surgery, Senior Associate Dean for Research, Icahn School of Medicine at Mount Sinai Learn more: http://www.modernhealthcare.com/article/20150311/NEWS/150319979/apples-researchkit- draws-massive-interest-and-some-reservations

Healio – March 12 Beta-Cell Proliferation Seen With Harmine Compound From Plant Used In Traditional Medicine A drug derived from a flowering plant found in the Middle East and in some South American vines appears to drive human insulin-producing beta cells to multiply, according to research published in Nature Medicine. “Currently, there are many diabetes drugs, but none address the unmet clinical need to induce human beta-cell regeneration,” Andrew Stewart, MD, director, Diabetes, Obesity and Metabolism Institute, Icahn School of Medicine, told Endocrine Today. In a robotic high-throughput screen of more than 102,300 potential drugs, Stewart and colleagues discovered that harmine — from the perennial Harmal (peganum Harmala), already used in traditional medicine — led to sustained division and multiplication of adult human beta cells in culture. - Dr. Andrew Stewart, Professor, Medicine, Endocrinology, Diabetes and Bone Disease, Director, Diabetes, Obesity and Metabolism Institute, Icahn School of Medicine at Mount Sinai Learn more: http://www.healio.com/endocrinology/diabetes/news/online/%7B08c29922-8c38-4b36-af9e- a78e47c251b4%7D/beta-cell-proliferation-seen-with-harmine-compound-from-plant-used-in- traditional-medicine

Medscape – March 12 Compound Trawl IDs Potential Beta-Cell Proliferation Drug – Liam Davenport A drug that can drive the division and proliferation of pancreatic beta cells at human physiological rates has been identified from a screening of over 100,000 compounds, potentially paving the way for a breakthrough in the management of diabetes. Using a high-throughput small-molecule screen, the team, led by Peng Wang, PhD, of the Icahn School of Medicine at Mount Sinai, New York, NY, found that harmine, derived from Harmal (Peganum harmala), a flowering plant found in the Middle East and some areas in South America, was able to sustainably drive beta-cell proliferation as well as improve glycemic control in culture. However, there is a drawback. In South America and the Middle East, people make tea from and smoke the Harmal plant because harmine is hallucinogenic, senior author Andrew Stewart, MD, director of the Diabetes, Obesity and Metabolism Institute at the Icahn School of Medicine, explained to Medscape Medical News. - Dr. Andrew Stewart, Professor, Medicine, Endocrinology, Diabetes and Bone Disease, Director, Diabetes, Obesity and Metabolism Institute, Icahn School of Medicine at Mount Sinai -Peng Wang, PhD, Assistant Professor, Medicine, Endocrinology, Diabetes and Bone Disease, Icahn School of Medicine at Mount Sinai Learn more: http://www.medscape.com/viewarticle/841364

Scientific American – March 13 How Identity Evolves in the Age of Genetic Imperialism – Eleonore Pauwels and Jim Dratwa From designer babies to women whose genitals smell like peaches, 2014 graced us with a taste of the hope, hype and superficiality of business as usual in Silicon Valley. It is tempting to listen to those who tell us that there is a gene-hack to solve every “problem”—that DNA is just a code to personalize at will. This brand of genetic determinism has invaded all realms of life, from our dating scene to our social networks. This becomes more sobering when one considers that scientists at The Mount Sinai Hospital in New York are investigating the genetic cause of suicide in the hope of developing suicide DNA tests. - The Mount Sinai Hospital Learn more: http://blogs.scientificamerican.com/guest-blog/2015/03/13/how-identity-evolves-in-the-age- of-genetic-imperialism/

Medpage Today – March 13 Heart Failure after CoreValve TAVR Reported – Crystal Phend Two cases of recurrent heart failure after receiving a CoreValve transcatheter aortic valve replacement (TAVR) device turned up calcified, thrombotic, degraded prostheses within 1 to 5 years, a German group reported. In an accompanying response in NEJM, Thomas A. Vassiliades, MD, MBA, of Medtronic in Minneapolis, agreed that interference of the prosthesis with normal movement of the anterior mitral valve leaflet was "evidence that the device was implanted too deeply within the left ventricular outflow tract" and "probably resulted in incomplete frame expansion." Deep implant probably explains the problems seen, suggested Vassiliades, along with co-authors David H. Adams, MD, of The Mount Sinai Hospital in New York City, and Jeffrey J. Popma, MD, of Beth Israel Deaconess Medical Center in Boston. - Dr. David Adams, Professor, System Chair, Cardiovascular Surgery, Icahn School of Medicine at Mount Sinai Learn more: http://www.medpagetoday.com/Cardiology/CHF/50439

The Wall Street Journal – March 13 Wine Headache? Chances Are It’s Not the Sulfites – Lettie Teague Contains Sulfites. This back-label notification has led to a great many misunderstandings among those who attribute health problems, primarily headaches, to sulfites in wine, specifically red wine. Beth Corn, MD, associate professor of medicine at New York’s Icahn School of Medicine at Mount Sinai and part of the faculty of the Department of Allergy and Clinical Immunology sees quite a few patients who believe they have wine-related allergies; the real problem, in some cases, probably has more to do with excess alcohol intake than sulfites. “Sometimes patients tell me they don’t have a reaction to wine if they stop at one glass,” said Dr. Corn, who replies, “Then, why don’t you stop at one glass?” - Dr. Beth Corn, Assistant Professor, Medicine, Clinical Immunology, Icahn School of Medicine at Mount Sinai Learn more: http://www.wsj.com/articles/wine-headache-chances-are-its-not-the-sulfites-1426250886 mHealth News – March 12 Telehealth takes off in the Northeast – Eric Wicklund At the beginning of the year, some analysts ventured that this might be the year that telehealth will take off. A pair of pilot projects springing up in the Northeast is lending weight to that prediction. In New York, Mount Sinai Health System is rolling out at least four new telehealth projects in an effort to scale up what has so far worked well in small settings. “Technology has evolved to a point where it is less of a novelty in our doctors’ offices and more of an essential part of our physicians’ toolkits – and, indeed, an everyday part of our patients’ lives," Kumar Chatani, executive vice president and chief information officer of the Mount Sinai Health System, said in a press release. "The time has come for telehealth to move to the next level by putting it into wider practice." Among the projects now underway, the Primary Care Program is enabling physicians in the Mount Sinai Doctors Family Practice to offer remote patient consults through a secure digital platform. "Telehealth is yet another access point for our patients who want to discuss their health concerns and new health problems with their own physician via a video consultation,” said Aida Vega, MD, director of Primary Care Associates at Mount Sinai and an associate professor of medicine at the Icahn School of Medicine at Mount Sinai, who's leading the Primary Care Program. - Kumar Chatani, Executive Vice President, Chief Information Officer, Mount Sinai Health System -Dr. Aida Vega, Associate Professor, Medicine, General Internal Medicine, Icahn School of Medicine at Mount Sinai Learn more: http://www.mhealthnews.com/news/telehealth-takes-northeast?page=0 Additional Coverage: FierceHealth IT: http://www.fiercehealthit.com/story/mount-sinai-turns-telemedicine-cut-ed-use- readmissions/2015-03-12 MedCity News: http://medcitynews.com/2015/03/mount-sinai-increase-telehealth-services/

Yahoo News via Reuters – March 12 Male Smokers Have Elevated Risk of Osteoporosis – Lisa Rapaport Male smokers have a greater risk for osteoporosis than other men and even than women smokers, a recent study finds, suggesting that U.S. screening guidelines focused on women might need to be expanded to include men. The U.S. Preventive Services Task Force (USPSTF), a government-backed independent organization that reviews medical evidence, last updated screening guidelines for osteoporosis in 2011. "The evidence in 2011 was insufficient to determine the balance of benefits and harms of screening men for osteoporosis because there were few relevant treatment studies in men," said Albert Siu, MD, a co-vice chair of the task force and a professor of geriatrics at the Icahn School of Medicine at Mount Sinai in New York City. - Dr. Albert Siu, Professor, Population Health and Policy, Medicine, General Internal Medicine, Geriatrics and Palliative Medicine, Icahn School of Medicine at Mount Sinai, Chair, Geriatrics and Palliative Medicine, the Mount Sinai Health System Learn more: http://news.yahoo.com/male-smokers-elevated-risk-osteoporosis-164837057.html

HealthDay – March 12 Cochlear Implants May Also Boost Seniors' Mood, Thinking: Study – Robert Preidt Cochlear implants not only boost hearing in seniors with severe hearing loss, they might also enhance their emotional state and thinking abilities, a new study finds. While the study couldn't prove cause- and-effect, the cochlear implants were associated with improved speech perception in quiet and noisy settings, better quality of life, lower rates of depression and improved thinking skills, the researchers found. Another expert in the United States wasn't surprised by the findings. "It has become increasingly recognized that deafness in the elderly population can be misdiagnosed as cognitive dysfunction or even dementia," said Eric Smouha, MD, director of otology and neurology at The Mount Sinai Hospital in New York City. He said the new findings have been replicated in prior studies conducted in the United States. -Dr. Eric Smouha, Associate Professor, Otolaryngology, Director, Otology, Neurology, Icahn School of Medicine at Mount Sinai Learn more: http://consumer.healthday.com/hearing-information-19/hearing-disorder-news- 351/cochlear-implants-may-also-boost-seniors-mood-thinking-study-697335.html

Medpage Today – March 12 Risky Business: Working Where Violence Is the Norm – Nicholas Genes, MD, PhD On Tuesday, Jan. 20, cardiac surgeon Michael J. Davidson was shot at his clinic at Brigham and Women's Hospital in Boston. The shooter, who also took his own life, was the son of 78-year-old Marguerite Pasceri, who had died shortly after a procedure Dr. Davidson had performed in November. Statistics about violence towards police reached mainstream news outlets after two NYPD officers were killed on the job in December. But what about emergency care personnel? How at risk are they to violence in our own emergency departments? For whatever reason, I hadn't really considered healthcare workers as a vulnerable population -- until the shooting in Boston. - Dr. Nicholas Genes, Assistant Professor, Emergency Medicine, Icahn School of Medicine at Mount Sinai Learn more: http://www.medpagetoday.com/Blogs/EPMonthly/50446

Allure – March 12 Is Kakadu Plum the Newest Must-Have Beauty Ingredient? – Stephanie Saltzman So, what exactly is kakadu plum? "It's a fruit grown in northern Australia that's rich in vitamin C," says Joshua Zeichner, MD, an assistant professor of dermatology at The Mount Sinai Hospital in New York City. "It's been shown to fight off cancer cells and may be helpful for UV-damaged skin," he adds. Though Zeichner stresses that there hasn't been much research on the efficacy of the ingredient yet, data from Food Chemistry and the U.S. Department of Agriculture suggests that kakadu plum contains 55 times more vitamin C than a Florida orange. - Dr. Joshua Zeichner, Assistant Professor, Dermatology, Icahn School of Medicine at Mount Sinai, Director, Cosmetic and Clinical Research in Dermatology, The Mount Sinai Hospital Learn more: http://www.allure.com/beauty-products/2015/kakadu-plum-skin-hair-products#intro

Health Aim – March 13 Healthy Ways to Exercise for Seniors – Belinda Peter A recent study conducted by a group of scientists from Rush University, Chicago has made the case for seniors to exercise more compelling. The study successfully pointed out that in order to prevent age- related injury to the brain it is a must to keep moving. Sam Gandy, MD, professor and associate director of the Mount Sinai Alzheimer’s Disease Research Centre in New York City remarked, “Virtually everything about Alzheimer’s and other dementia appears to be mitigated by physical exercise. I think this study serves to make that case even more compelling.” - Dr. Samuel Gandy, Professor, Neurology, Psychiatry, Icahn School of Medicine at Mount Sinai, Associate Director, Mount Sinai Alzheimer’s Disease Research Center Learn more: http://www.healthaim.com/healthy-ways-exercise-seniors/16616 Additional Coverage: Pioneer News: http://www.piercepioneer.com/study-indicates-a-little-exercise-can-go-a-long-way-to- improve-motor-function-in-elders/38805 Magallanes Deportes (Chile): http://www.magallanesdeportes.cl/2015/03/el-efecto-de-la-actividad-fisica- sobre.html [Article is in Spanish]

KPIU 88.5 – March 12 Why Does A Playground Activity That All Kids Love Make So Many Adults Sick? – Gabriel Spitzer Kids love the swings. So much, in fact, that kids seem to be able to swing endlessly without tiring of it a bit. I observed this in my own children and decided to hop on one as a thirty-something dad. Within seconds I made a startling discovery: Swings make geezers like me sick really, really fast. Just a minute or two into the fun, and I found I was dizzy, uncomfortable and sloshing toward outright nausea. I called neurologist Bernie Cohen, MD, of The Mount Sinai Hospital in New York, a widely respected expert on the vestibular system. He told me, first of all, that any change was more likely neurological or psychological rather than physical. And he told me that, basically, science doesn’t know the answer. “If you look to see what the scientific basis for it is, it’s not there,” he said. - Dr. Bernard Cohen, Professor, Neurology, Icahn School of Medicine at Mount Sinai Learn more: http://www.kplu.org/post/why-does-playground-activity-all-kids-love-make-so-many- adults-sick

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: [email protected] on behalf of Lindo, Allisa Subject: Mount Sinai In The News - March 12, 2015 Date: Thursday, March 12, 2015 11:29:39 AM Attachments: ATT00001.txt

In the News March 12, 2015

Bloomberg Business – March 11 How the iPhone Is Helping Doctors Battle Diseases – Cory Johnson Eric Schadt, PhD, of The Mount Sinai Hospital discusses the Apple ResearchKit with Bloomberg's Cory Johnson on "Bloomberg West." “I think the advances we are seeing in these mobile health apps, with sophisticated devices like the iPhone, is that you can do a lot more than just track steps and your activity rate. We can connect devices,” says Schadt. He continues, “For example, our asthma study we’ll be able to have Bluetooth enabled inhalers. We’ll know when somebody’s inhaling, how much they’re inhaling throughout the day.” -Eric Schadt, PhD, Jean C. and James W. Crystal Professor of Genomics, Chair, Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, Director, Icahn Institute for Genomics and Multiscale Biology Learn more: http://www.bloomberg.com/news/videos/2015-03-11/how-the-iphone-is-helping-doctors-battle-diseases Additional Coverage: Panama On: http://www.panamaon.com/noticias/tecnologia/1161725-apple-presenta-researchkit-que-proporciona-a-los- investigadores-medicos-las-herramientas-para-revolucionar-los-estudios-medicos.html [Article is in Spanish]

Business Insider via Reuters – March 11 Hospital Admissions for Chest Pain May Result From Poor Communication – Lisa Rapaport Poor communication may lead some patients with chest pain to be admitted to the hospital even when their risk for a heart attack is low, a small study suggests. "Ideally, you want the conversation between a physician and a patient to be as straightforward as possible, but in our study of admissions for cardiac observation, we found the risks of going home were terribly overinflated and so was the potential benefit of staying overnight in the hospital," said lead study author David Newman, MD, a researcher in emergency medicine at the Icahn School of Medicine at Mount Sinai in New York City. -Dr. David Newman, Associate Professor, Emergency Medicine, Director of Clinical Research, Department of Emergency Medicine, Icahn School of Medicine at Mount Sinai Learn more: http://www.businessinsider.com/r-hospital-admissions-for-chest-pain-may-result-from-poor-communication- 2015-3 Additional Coverage: News Medical: http://www.news-medical.net/news/20150312/Survey-Physicians-patients-overestimate-risk-of-heart-attack- or-death-for-possible-ACS.aspx

Cancer Discovery – March 10 MAPK-Driven Transformation Requires DRP1-Mediated Mitochondrial Division Major finding: RAS-induced tumor growth requires dynamin-related protein 1 (DRP1)–driven mitochondrial fission. Mechanism: ERK1/2-mediated phosphorylation of DRP1 at Ser616 promotes mitochondrial fission and dysfunction. Impact: MAPK inhibitors target mitochondrial division and increase sensitivity to mitochondrial uncouplers. - Madhavika Serasinghe, PhD, Instructor, Oncological Sciences, Icahn School of Medicine at Mount Sinai Learn more: http://cancerdiscovery.aacrjournals.org/content/early/2015/02/18/2159-8290.CD-RW2015-031.full

Crain’s Health Pulse – March 12 Who’s News Jagat Narula, MD, was promoted to chief of cardiology at Mount Sinai St. Luke's and Mount Sinai Roosevelt. He continues as director of cardiovascular imaging for the Mount Sinai Health System, as well as professor of medicine (cardiology) and radiology, and associate dean for global affairs at Icahn School of Medicine at Mount Sinai. - Dr. Jagat Narula, Professor, Medicine, Cardiology, Radiology, Associate Dean for Global Affairs, Icahn School of Medicine at Mount Sinai, Chief, Cardiology, Mount Sinai St. Luke’s, Mount Sinai Roosevelt, Director, Cardiovascular Imaging, Mount Sinai Health System Learn more: http://www.crainsnewyork.com/article/20150312/PULSE/150319955/senate-budget-bills-500m-spending-boost#

Health Desk (Italy) – March 11 Diabetes, from Nature a Potential New Drug That Regenerates Beta Cells It's called harmine, is an alkaloid found in a plant in the Middle East and South America and some vines could become the new weapon for the treatment of diabetes. Of the 100, 000 potential drugs looked at by researchers at the Icahn School of Medicine Mount Sinai, in fact, only this substance has managed to multiply the beta cells of the pancreas, the ones that in the case of diabetes occur in low numbers and produce little insulin. " Although we still have a lot of work to do in improving the specificity and potency of the harmine and related compounds, we believe that these results represent an important step towards the future more effective treatment of diabetes," said Andrew Stewart, MD, Director of Diabetes, Obesity and Metabolism Institute of Mount Sinai and one of the study authors. - Dr. Andrew Stewart, Professor, Medicine, Endocrinology, Diabetes and Bone Disease, Director, Diabetes, Obesity and Metabolism Institute, Icahn School of Medicine at Mount Sinai Learn more: http://www.healthdesk.it/ricerca/diabete_dalla_natura_un_nuovo_potenziale_farmaco_che_rigenera_le_cellule_beta/1426089600 [Article is in Italian]

WNYW – March 10 Therapy Dogs and Cancer – Linda Schmidt A new study says man’s best friend can also give an emotional lift to those suffering from cancer. A six year study from Mount Sinai Beth Israel found that canine companions improve the patients’ emotional and social wellbeing. Daniel Labow, MD, a surgeon at The Mount Sinai Hospital, believes that therapy dogs can play a crucial role in a patient’s recovery. He says, “In many ways it keeps them alive because it keeps them motivated to get the treatment.” -Dr. Daniel Labow, Associate Professor, Surgery, Surgical Oncology, Icahn School of Medicine at Mount Sinai Learn more: http://www.myfoxny.com/story/28359313/the-power-of-therapy-dogs?clienttype=generic&mobilecgbypass

HIT Consultant – March 12 Mount Sinai Health System Launches Telehealth Pilot Projects – Fred Pennic Using secure digital conferencing technology, patients can now manage their health, meet with physicians, and receive advice from Mount Sinai Health System experts – all without setting foot in a doctor’s office. These initiatives are part of NYC-based Mount Sinai’s growing new telehealth offerings, which help provide comprehensive, cost-effective care through the use of technology. “Technology has evolved to a point where it is less of a novelty in our doctors’ offices and more of an essential part of our physicians’ toolkits – and, indeed, an everyday part of our patients’ lives. The time has come for Telehealth to move to the next level by putting it into wider practice, and we’re proud to have done that here at Mount Sinai, which is at the forefront of the Telehealth revolution,” said Kumar Chatani, Executive Vice President and Chief Information Officer for the Mount Sinai Health System in a statement. - Kumar Chatani, Executive Vice President, Chief Information Officer, Mount Sinai Health System -Dr. Aida Vega, Associate Professor, Medicine, General Internal Medicine, Icahn School of Medicine at Mount Sinai Learn more: http://hitconsultant.net/2015/03/12/mount-sinai-health-system-launches-telehealth-pilot-projects/

The New York Times – March 11 On Ferrets, New York’s Health Board Displays Rare Apathy – Anemona Hartocollis The city’s Board of Health decided not to overturn a nearly 16-year-old ban on keeping ferrets as pets. The vote was 3 to 2 in favor of lifting the ban, but of the 10 members, five abstained, making it impossible to get the necessary majority for either side. Most of the board members declined to comment on Wednesday. But one abstaining member shared the concerns raised at the hearing by a fellow member, Lynne Richardson, MD, vice chairwoman of emergency medicine at the Icahn School of Medicine at Mount Sinai. Before the vote on Tuesday, Dr. Richardson said ferret ownership was “uniquely problematic” because ferrets, unlike dogs and cats, could slink through holes and cracks in dilapidated New York City apartments and attack infants in neighboring units. - Dr. Lynne Richardson, Professor, Emergency Medicine, Population Health Science and Policy, Vice Chair for Academic, Research and Community Programs, Department of Emergency Medicine, Icahn School of Medicine at Mount Sinai Learn more: http://www.nytimes.com/2015/03/12/nyregion/on-ferrets-new-yorks-heath-board-displays-rare-apathy.html? _r=0

HealthDay – March 11 Exercise's Effect on Brain May Boost Mobility in Old Age – Steven Reinberg Staying physically active as you age may ward off brain damage that can limit mobility, a small study says. Small areas of brain damage called white matter hyperintensities are seen in MRI scans of many older patients, according to scientists from Rush University Medical Center in Chicago. Higher levels of this damage have been linked to difficulty walking and other mobility problems, the researchers said. Sam Gandy, MD, professor and associate director of the Mount Sinai Alzheimer's Disease Research Center in New York City, called this an "extremely important" study. "Virtually everything about Alzheimer's and other dementia appears to be mitigated by physical exercise," he said. "I think that this study serves to make that case even more compelling." - Dr. Samuel Gandy, Professor, Neurology, Psychiatry, Icahn School of Medicine at Mount Sinai, Associate Director, Mount Sinai Alzheimer’s Disease Research Center Learn more: http://consumer.healthday.com/senior-citizen-information-31/misc-aging-news-10/exercise-may-help-elderly- stay-mobile-697337.html Additional Coverage: U.S. News & World Report: http://health.usnews.com/health-news/articles/2015/03/11/exercises-effect-on-brain-may-boost- mobility-in-old-age SMN Weekly: http://www.smnweekly.com/exercise-may-keep-you-moving-even-in-old-age/21013/

The Daily Beast via Daily Burn – March 11 The Low-FODMAP Diet: Your Solution to a Healthier Gut? – Alex Orlov A 2013 study published in the journal Gastroenterology revealed that individuals with non-celiac gluten sensitivity could benefit greatly from omitting FODMAPS-rich foods from their diets. “This was a very impressive study,” says Gina Sam, MD, MPH Director of the Mount Sinai Gastrointestinal Motility Center at the Mount Sinai Hospital. Though there were only 37 participants, the results were remarkable enough for the medical community to take notice. “Patients on the low-FODMAPs diet had dramatic improvements in pain, bloating and stool consistency,” she says. - Dr. Gina Sam, Assistant Professor, Medicine, Gastroenterology, Icahn School of Medicine at Mount Sinai, Director, Mount Sinai Gastrointestinal Motility Center at the Mount Sinai Hospital Learn more: http://www.thedailybeast.com/articles/2015/03/11/the-low-fodmap-diet-your-solution-to-a-healthier-gut.html

HealthDay – March 11 Study Highlights Complexity of 'Hearing Voices' – Robert Preidt A new study from Durham University highlights the complexity and variety of the "voices" some psychiatric patients and others experience. The study was led by Angela Woods of Durham's Center for Medical Humanities. It included 127 people who had been diagnosed with a psychiatric disorder and 26 others with no history of mental illness. Many said they hear multiple voices (81 percent) with distinct, character-like qualities (70 percent). Two-thirds said they also experience physical effects from the voices, such as hot or tingling sensations in their hands and feet. Experts in the United States agreed the new findings are important. Sophia Frangou, MD, is chief of the psychosis research program at Icahn School of Medicine in New York City. She said that while the study of voices "goes back a very long way," the new report "makes a small but interesting contribution." - Dr. Sophia Frangou, Professor, Psychiatry, Chief of the Psychosis Research Program in the Division of Psychiatric Genomics, Department of Psychiatry, Icahn School of Medicine at Mount Sinai Learn more: http://consumer.healthday.com/mental-health-information-25/psychology-and-mental-health-news-566/study- highlights-complexity-of-hearing-voices-697323.html

Deccan Herald via The New York Times – March 12 Blocking the Paths to Suicide – Celia Watson Seupel Every year, nearly 40,000 Americans kill themselves. The majority are men, and most of them use guns. In fact, more than half of all gun deaths in the United States are suicides. Igor Galynker, PhD, the director of biological psychiatry at Mount Sinai Beth Israel, noted that in one study, 60 percent of patients who were judged to be at low risk died of suicide after their discharge from an acute care psychiatric unit. “The assessments are not good,” he said. So Dr. Galynker and his colleagues are developing a novel suicide assessment to predict imminent risk, based upon new findings about the acute suicidal state. - Igor Galynker, PhD, Professor, Psychiatry, Icahn School of Medicine at Mount Sinai, Director, Division of Biological Psychiatry, Mount Sinai Beth Israel Learn more: http://www.deccanherald.com/content/464955/blocking-paths-suicide.html

Arizona Jewish Post – March 12 Feeling Panicked? It could be in the Genes Just how much such epigenetic changes impact human behavior remains largely unknown, researchers acknowledge. “We certainly know that human experiences affect how our genes are expressed,” says Rachel Yehuda, a professor of psychiatry and neuroscience at the Icahn School of Medicine at Mount Sinai Hospital in New York, who has performed epigenetic studies on Holocaust survivors. “But we don’t know for sure how this process works and how strong a contributor epigenetics really is compared to other things like genes.” - Rachel Yehuda, PhD, Professor of Psychiatry and Neuroscience and Director of the Traumatic Stress Studies Division at the Icahn School of Medicine at Mount Sinai, Director, Mental Health Patient Care Center and PTSD Research Program at the James J. Peters Veterans Affairs Medical Center in the Bronx Learn more: http://azjewishpost.com/2015/feeling-panicked-it-could-be-in-the-genes/

Newsmax – March 12 Erase Skin Aging without Surgery – Michele Bender The sun may feel good, but it can wreak havoc on your skin. Besides the serious threat of cancer, UV rays can break down the skin’s collagen and elastin, causing fine lines and wrinkles, aging you before your time. “Even if you spent your childhood basking in the sun, it doesn’t mean you have to live with the cosmetic damage,” explains Francesca Fusco, MD, assistant clinical professor of dermatology at the Icahn School of Medicine at Mount Sinai. “There’s a lot you can do to erase it and take years off your face.” -Dr. Francesca Fusco, Assistant Clinical Professor, Dermatology, Icahn School of Medicine at Mount Sinai Learn more: http://www.newsmax.com/Health/Health-News/erase-skin-aging-nonsurgery/2015/03/12/id/629716/

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: [email protected] on behalf of Lindo, Allisa Subject: Mount Sinai In The News - March 11, 2015 Date: Wednesday, March 11, 2015 11:37:10 AM Attachments: ATT00001.txt

In the News March 11, 2015

Business Insider – March 10 Apple Is Ushering In a 'New Era' Of Medical Research – Kevin Loria Some of Apple's announcements from yesterday are sure to sell watches and computers to those in the market for them, but only one announcement could actually transform people's lives and open up a new era of medicine: ResearchKit. Using ResearchKit, medical researchers can develop iPhone apps that provide medical information to individuals and collect data from users that can then be used to develop future treatments. Five launch apps developed with some of the top universities and research institutions in the country will collect information on asthma, Parkinson's, breast cancer, diabetes, and heart health. "We're hopeful that this could potentially be one of the — if not the — largest real world epidemiological studies in asthma ever," says Yvonne Chan, MD, a researcher and assistant professor of emergency medicine, genetics, and genomic sciences at The Mount Sinai Hospital, the research institution that partnered with Apple to launch the asthma app. - Dr. Yvonne Chan, Assistant Professor, Genetics and Genomic Sciences, Emergency Medicine, Director, Personalized Medicine and Digital Health, Icahn School of Medicine at Mount Sinai Learn more: http://www.businessinsider.com/apple-researchkit-could-transform-medical-research-2015-3

CNBC – March 10 Apple's ResearchKit: Game Changer for Digital Health Care? – Bertha Coombs Just as the launch of Apple's iPod and iTunes proved to be the tipping point in digital music, some are speculating that Apple's new platform for medical researchers and its Apple Watch, could do the same for digital, data-driven health care. Apple announced Monday a new open-source platform called ResearchKit to help health researchers enlist and monitor research subjects through Apple devices. "This is a new era," said Yvonne Chan, director of personalized medicine and digital health at the Icahn School of Medicine at Mount Sinai in New York. "This is really, truly revolutionizing the way clinical research could be done in the future." The Mount Sinai Hospital is one of five medical facilities that will conduct clinical trials using ResearchKit. - Dr. Yvonne Chan, Assistant Professor, Genetics and Genomic Sciences, Emergency Medicine, Director, Personalized Medicine and Digital Health, Icahn School of Medicine at Mount Sinai Learn more: http://www.cnbc.com/id/102492219

Genetic Engineering & Biotechnology News – March 11 Breathing Easier: Apple ResearchKit Aids Asthma Trial– Alex Philippidis LifeMap Solutions joined with Icahn School of Medicine at Mount Sinai to develop Asthma Help, one of five apps Apple revealed Monday when it announced ResearchKit. The software framework, to be released next month, is designed to enable doctors and researchers to gather data more frequently and more accurately from participants via iPhone apps. “Now we can reach all corners of the globe to recruit research volunteers and conduct medical research with sample sizes that are orders of magnitude greater than previously possible for a fraction of the cost,” Eric Schadt, Ph.D., the Jean C. and James W. Crystal Professor of Genomics at the Icahn School of Medicine at Mount Sinai, said in a statement. -Eric Schadt, PhD, Jean C. and James W. Crystal Professor of Genomics, Chair, Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, Director, Icahn Institute for Genomics and Multiscale Biology Learn more: http://www.genengnews.com/gen-news-highlights/breathing-easier-apple-researchkit-aids-asthma-trial/81251019/ Additional Coverage: Health IT Analytics: http://healthitanalytics.com/2015/03/10/will-apple-watch-be-the-mhealth-answer-to-big-data-analytics/ NetzWelt (Germany): http://www.netzwelt.de/news/151636-apple-watch-kaeufertreudoofe-kaninchen-echte-helden.html [Article is in German] Today Haber (Turkey): http://www.todayhaber.com/saglik/appledan-doktorlara-mujde-researchkit-h7331.html [Article is in Turkish] Albawaba: http://www.albawaba.com/business/apple-keeps-doctor-away-apples-great-ambitions-health-apps-667688

Medical Xpress – March 11 Physicians and Patients Overestimate Risk of Death from Acute Coronary Syndrome Both physicians and patients overestimate the risk of heart attack or death for possible acute coronary syndrome (ACS) as well as the potential benefit of hospital admission for possible ACS. A survey of patient and physician communication and risk assessment, along with an editorial, were published online last week in Annals of Emergency Medicine. "Even immediately after the patient and doctor discuss the reasons for hospital admission, it turns out we're disagreeing about those reasons two-thirds of the time," said lead study author David Newman, MD, of the Icahn School of Medicine at Mount Sinai in New York, N.Y. "In many ways, it seems almost like we're ships passing in the night.” -Dr. David Newman, Associate Professor, Emergency Medicine, Director of Clinical Research, Department of Emergency Medicine, Icahn School of Medicine at Mount Sinai Learn more: http://medicalxpress.com/news/2015-03-physicians-patients-overestimate-death-acute.html

Diabetes.co.uk – March 11 Harmine Drug That Restores Beta Cells Seen As Key Diabetes Treatment A chemical called harmine, which occurs naturally in a number of plants around the world, has been shown to regenerate pancreatic cells lost in diabetes. Type 1 diabetes is characterized by the immune system attacking insulin-producing pancreatic beta cells, while beta cell deficiency has been observed as a contributor to type 2 diabetes. Andrew Stewart, MD, Director of the Diabetes, Obesity and Metabolism Institute at the Icahn School of Medicine in the US, concluded: "We believe these results represent a key step toward more effective treatment of diabetes. “Our results provide a large body of evidence demonstrating that the harmine drug class can make human beta cells proliferate at levels that may be relevant for diabetes treatment. We still have a lot of work to do in improving the specificity and potency of the harmine and related compounds," Stewart added. - Dr. Andrew Stewart, Professor, Medicine, Endocrinology, Diabetes and Bone Disease, Director, Diabetes, Obesity and Metabolism Institute, Icahn School of Medicine at Mount Sinai Learn more: http://www.diabetes.co.uk/news/2015/mar/harmine-drug-that-restores-beta-cells-seen-as-key-diabetes-treatment-91533665.html Additional Coverage: MPR: http://www.empr.com/harmine-future-diabetes-drug-class/article/402713/

HealthDay – March 10 More Evidence That Hormone Therapy Might Not Help Women's Hearts – Robert Preidt There's yet another study looking at the potential dangers of hormone replacement therapy for menopausal symptoms, and this one supports the notion that the treatment may not help women's hearts. The research, a review of collected data on the issue, found that hormone replacement therapy (HRT) does not protect most postmenopausal women against heart disease and may even increase their risk of stroke. Taraneh Shirazian, MD, is an assistant professor of obstetrics, gynecology and reproductive sciences at the Icahn School of Medicine at Mount Sinai, in New York City. She said that, as of now, HRT "use is recommended for the shortest period of time for symptom control due to the risks of blood clots, stroke and slight increase in breast and ovarian cancer risk." - Dr. Taraneh Shirazian, Assistant Professor, Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai Learn more: http://consumer.healthday.com/women-s-health-information-34/hormone-replacement-therapy-news-387/more-evidence-that-hormone- therapy-might-harm-women-s-hearts-697254.html Additional Coverage: Philly.com: http://www.philly.com/philly/health/topics/HealthDay697254_20150310_More_Evidence_That_Hormone_Therapy_Might_Not_Help_Women_s_Hearts.html

Newsweek – March 10 Water Fluoridation Linked to Higher ADHD Rates – Douglas Main New research shows there is a strong correlation between water fluoridation and the prevalence of Attention Deficit Hyperactivity Disorder, or ADHD, in the United States. The study, published in the journal Environmental Health, found that states with a higher portion of artificially fluoridated water had a higher prevalence of ADHD. Previous research has suggested that there may be several mechanisms by which fluoride could interfere in brain development and play a role in ADHD, says Caroline Martinez, MD, a pediatrician and researcher at The Mount Sinai Hospital in New York. -Dr. Caroline Martinez, Assistant Clinical Professor, Pediatrics, Behavioral Pediatrics, Icahn School of Medicine at Mount Sinai Learn more: http://www.newsweek.com/water-fluoridation-linked-higher-adhd-rates-312748

Medical Technology Schools – February 2015 25 Top Radiology Professors Radiology is a rapidly advancing field, and as the technology and methodology becomes more advanced, it is vital that radiology students learn from professors who have not only mastered their craft, but also demonstrated a commitment to further innovation and development of the science. By scouring the most important radiologic publications, research, and programs from around the country, we’ve found professors on the vanguard of the science of radiology, and listed them here. Burton P. Drayer has served as the Executive Vice-President for Risk as well as a Professor and the Chair of the Department of Radiology at Icahn School of Medicine at Mount Sinai since 1995. He previously served as President of The Mount Sinai Hospital from November 2003 to September 2008. - Dr. Burton Drayer, Dr. Charles M. and Marilyn Newman Professor, Radiology, Chair, Department of Radiology, Dean for Clinical Affairs, Icahn School of Medicine at Mount Sinai, Executive Vice President for Risk, The Mount Sinai Hospital Learn more: http://www.medicaltechnologyschools.com/radiologic-technologist/top-radiology-professors

WNBC TV – March 10 Kidney Cancer Awareness Month March is Kidney Cancer Awareness Month, a time to discuss the disease, detection and treatments for it. Ketan Badani, MD, is the Director of the Comprehensive Kidney Cancer Program at Mount Sinai Health System. He sits down with WNBC to discuss the disease. “The kidneys are very complex, small organs. They are about fist size and you have two of them sort of in the middle of your back. Kidney cancer is a top ten cancer in both men and women. About 68,000 to 70,000 new patients are diagnosed with kidney cancer in the U.S. every year,” says Dr. Badani, “If found early this is one of the most curable cancers out there.” - Dr. Ketan Badani, Senior Faculty, Urology, Icahn School of Medicine at Mount Sinai, Director, Comprehensive Kidney Cancer Program, Vice Chairman, Urology and Robotic Operations, Mount Sinai Health System Learn more: No Web Link Available

WCBS TV – March 10 All About Your Allergies – Max Gomez Peanut allergies have gone up 500% in the last 15 years. That’s spurring research into cures for peanut and other childhood food allergies. One study uses a patch to introduce peanut protein through the skin of children affected by peanut allergies, decreasing their allergy. “We are trying to introduce a very small amount of protein through normal skin, because if foreign protein goes in through normal skin it will also induce tolerance,” says Hugh Sampson, MD, of The Mount Sinai Hospital. The patch seems to have fewer adverse reactions and may also induce longer lasting peanut tolerance than oral desensitization. - Dr. Hugh Sampson, Professor, Pediatrics, Allergy and Immunology, Dean, Translational Biomedical Research, Icahn School of Medicine at Mount Sinai Learn more: No Web Link Available

Lower Extremity Review Magazine – February 2015 Peripheral Neuropathy in Lyme Disease Patients – Greg Gargiulo Approximately 30,000 cases of Lyme disease are reported to the Centers for Disease Control and Prevention (CDC) every year, though the actual number of diagnosed cases is much higher.17 This results in a mean annual national incidence of 9.7 cases per 100,000, but in highly endemic Connecticut, that figure is 74 per 100,000.2,4 Whether through increased awareness, incidence, or reporting, the annual number of reported cases of Lyme has more than doubled since 1991.3,4 “It’s possible that with the publicity surrounding Lyme, and physicians and patients being more aware of it, it may just be getting diagnosed more frequently because it’s being looked for more,” said David Simpson, MD, professor of neurology and director of the Clinical Neurophysiology Laboratories at the Icahn School of Medicine at Mount Sinai in New York, NY . - Dr. David Simpson, Professor, Neurology, Neuromuscular Diseases, Icahn School of Medicine at Mount Sinai, Director, Clinical Neurophysiology Laboratories, The Mount Sinai Hospital Learn more: http://lermagazine.com/article/peripheral-neuropathy-in-lyme-disease-patients

Capital New York – March 10 City Keeps Ferret Ban, Frustrating Advocates – Dan Goldberg The New York City Board of Health on Tuesday voted down a measure that would have legalized pet ferrets in New York City, disappointing a vocal pro- ferret constituency that had cheered the possible change. Board member Lynne Richardson, MD, a professor of emergency medicine, health evidence and policy, and vice chair of emergency medicine at the Icahn School of Medicine at Mount Sinai, expressed concern over the "unique skeletal structure of ferrets that allows them to squeeze through very small crevices," potentially enabling them to reach infants in other rooms or apartments. - Dr. Lynne Richardson, Professor, Emergency Medicine, Population Health Science and Policy, Vice Chair for Academic, Research and Community Programs, Department of Emergency Medicine, Icahn School of Medicine at Mount Sinai Learn more: http://www.capitalnewyork.com/article/city-hall/2015/03/8563766/city-keeps-ferret-ban-frustrating-advocates

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: [email protected] on behalf of Lindo, Allisa Subject: Mount Sinai In The News - March 10, 2015 Date: Tuesday, March 10, 2015 11:12:06 AM Attachments: ATT00001.txt

In the News March 10, 2015

ABC News via Good Morning America – March 9 Apple (AAPL) ResearchKit Introduced for Medical Research, Use – Susanna Kim Apple says it wants to turn the iPhone into a "powerful" tool for medical research and collect health data from users. ResearchKit is an open-source software kit designed for medical and health research to help doctors and scientists gather data from willing participants. ResearchKit was among several announcements at today’s highly anticipated event in San Francisco. The Asthma Health app, developed by the Icahn School of Medicine at Mount Sinai and LifeMap Solutions, used ResearchKit to facilitate asthma patient education and self-monitoring among other uses. - Icahn School of Medicine at Mount Sinai Learn more: http://abcnews.go.com/Business/apple-aapl-researchkit-medical-research/story? id=29504721 Additional Coverage: Politico: http://www.politico.com/story/2015/03/apples-researchkit-wants-to-change-traditional- medical-research-115918.html Wired: http://www.wired.com/2015/03/apples-new-researchkit-app-framework-medical-research/ USA Today: http://www.usatoday.com/story/tech/personal/2015/03/09/apple-watch-live- coverage/24638695/ Stuff.tv: http://www.stuff.tv/news/why-apples-researchkit-more-exciting-new-macbook-or-apple-watch

Healthline News – March 9 Psychoactive Plant May Hold Key to Reversing Diabetes – R. Sam Barclay New research published in Nature Medicine may have unlocked a new line of treatment for diabetes. The researchers honed in on the main culprits in diabetes: beta cells. These cells concentrate in the pancreas in little clusters called islets, and they produce the insulin necessary to keep the body’s blood sugar levels stable. “In children and adults with type 1 diabetes, they’ve lost 99 percent of their beta cells, so they cannot make enough insulin. That’s the cause of their diabetes,” said Andrew Stewart, director of the Diabetes, Obesity and Metabolism Institute at the Icahn School of Medicine at Mount Sinai, New York City and senior author of the study, in an interview with Healthline. - Dr. Andrew Stewart, Professor, Medicine, Endocrinology, Diabetes and Bone Disease, Director, Diabetes, Obesity and Metabolism Institute, Icahn School of Medicine at Mount Sinai Learn more: http://www.healthline.com/health-news/psychoactive-plant-may-hold-key-to-reversing- diabetes-030915 Additional Coverage: Express (UK): http://www.express.co.uk/life-style/health/562904/Plant-with-similar-effects-to-cocaine- and-LSD-could-be-key-to-diabetes-cure Medical Xpress: http://medicalxpress.com/news/2015-03-drug-candidate-regenerates-pancreatic- cells.html

International Business Times – March 10 A Sense of Purpose May Reduce Risk of Heart Diseases -- New Study – Samantha Richardson A new study has found that apart from medication and adopting a healthy lifestyle, having a sense of purpose in life reduces the risk of heart diseases and stroke. The study conducted by researchers at Mount Sinai St. Luke's and Mount Sinai Roosevelt, defined this purpose as a passion for life. Lead author Randy Cohen, MD, a preventive cardiologist at Mount Sinai St. Luke's and Mount Sinai Roosevelt suggests that everyone should begin asking themselves as to what the purpose of their life is and in the circumstance of one finding that he has no goal or purpose, one should develop it. Alan Rozanski, MD, study co-author and Director of Wellness and Prevention Programs for Mount Sinai Heart at the Mount Sinai Health System stated that this isn’t the first research to bring to light the impact positive emotions have on the heart. - Dr. Randy Cohen, Medical Director, University Medical Practice Associates, Mount Sinai St. Luke’s Roosevelt - Dr. Alan Rozanski, Professor, Medicine, Cardiology, Icahn School of Medicine at Mount Sinai, Director, Wellness and Prevention Programs, The Mount Sinai Hospital Learn more: http://au.ibtimes.com/sense-purpose-may-reduce-risk-heart-diseases-new-study-1427605 Additional Coverage: American Heart Association: http://blog.heart.org/sense-of-purpose-may-lower-risk-of-death-heart- attack-stroke/ The Washington Times: http://www.washingtontimes.com/news/2015/mar/9/happy-medicine- cardiologists-say-sense-purpose-lif/ Yahoo News via Indo Asian News Service: http://news.yahoo.com/sense-purpose-life-protect-heart- 084822886.html National Monitor: http://natmonitor.com/2015/03/07/having-a-sense-of-purpose-extends-your-lifespan/ Science World Report: http://www.scienceworldreport.com/articles/23092/20150306/protect-your-heart- with-a-sense-of-meaning-in-life.htm Univision: http://salud.univision.com/es/coraz%C3%B3n-y-circulaci%C3%B3n/tener-prop%C3%B3sitos- en-la-vida-protege-el-coraz%C3%B3n [Article is in Spanish] Economic Times (India): http://economictimes.indiatimes.com/magazines/panache/have-a-sense-of- purpose-in-life-to-protect-heart/articleshow/46501228.cms Elite Daily: http://elitedaily.com/news/world/finding-purpose-helps-you-live-longer/959713/

IT Wire – March 9 Apple’s MUST-SEE March 2015 Keynote – Alex Zaharov-Reutt If you haven’t yet seen Apple’s March 2015 ‘Spring Forward’ keynote, it is Apple’s best yet. It all went off without a hitch, with Tim Cook talking about Apple’s amazing new stores in China, before going to on talk about ResearchKit - a new way for anyone to take part in medical research without any data going to Apple, and which will help revolutionize medicine, medical monitoring and the way patients are treated. Eric Schadt, PhD, the Jean C. and James W. Crystal Professor of Genomics at the Icahn School of Medicine at Mount Sinai said, “When it comes to researching how we can better diagnose and prevent disease, numbers are everything. By using Apple’s new ResearchKit framework, we’re able to extend participation beyond our local community and capture significantly more data to help us understand how asthma works.” -Eric Schadt, PhD, Jean C. and James W. Crystal Professor of Genomics, Chair, Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, Director Icahn Institute for Genomics and Multiscale Biology Learn more: http://www.itwire.com/opinion-and-analysis/fuzzy-logic/67225-apple%E2%80%99s-must- see-march-2015-keynote-watch-now

Genome Web – March 9 Medical Data-Crunching Jeffrey Hammerbacher has charted a course from Bear Stearns in 2005 to Facebook in 2006 to Cloudera in 2008, notes Steve Lohr in an adapted excerpt from his book Data-ism: The Revolution Transforming Decision Making, Consumer Behavior, and Almost Everything Else appearing in the New York Times. As Lohr reports, Eric Schadt recruited Hammerbacher to The Mount Sinai Hospital as part of the school's bid to make medicine more data-driven. "We are trying to move medicine in the direction of climatology and physics; disciplines that are far more advanced and mature quantitatively," Schadt tells Lohr. -Jeff Hammerbacher, Assistant Professor, Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai -Eric Schadt, PhD, Jean C. and James W. Crystal Professor of Genomics, Chair, Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, Director Icahn Institute for Genomics and Multiscale Biology Learn more: https://www.genomeweb.com/scan/medical-data-crunching

The New York Times – March 9 Blocking the Paths to Suicide – Celia Watson Seupel Every year, nearly 40,000 Americans kill themselves. The majority are men, and most of them use guns. In fact, more than half of all gun deaths in the United States are suicides. Igor Galynker, PhD, the director of biological psychiatry at Mount Sinai Beth Israel, noted that in one study, 60 percent of patients who were judged to be at low risk died of suicide after their discharge from an acute care psychiatric unit. “The assessments are not good,” he said. So Dr. Galynker and his colleagues are developing a novel suicide assessment to predict imminent risk, based upon new findings about the acute suicidal state. - Igor Galynker, PhD, Professor, Psychiatry, Icahn School of Medicine at Mount Sinai, Director, Division of Biological Psychiatry, Mount Sinai Beth Israel Learn more: http://www.nytimes.com/2015/03/10/health/blocking-the-paths-to-suicide.html?_r=0

U.S. News & World Report – March 9 Managing Food Allergies: 5 Surprising New Approaches to Prevention, Diagnosis and Treatment – Deborah Kotz Babies with early signs of food allergies don’t necessarily need to avoid allergenic foods. That’s according to a recent landmark clinical trial published in the New England Journal of Medicine. It found that introducing peanut-containing foods into the diets of babies under age 1 who are prone to allergies is a safe practice and drastically reduces their risk of developing peanut allergies later on. “Current guidelines from the American Academy of Pediatrics don’t restrict when certain types of foods are introduced even in those with food allergies in the family,” says Scott Sicherer, a professor of pediatrics at the Jaffe Food Allergy Institute at Mount Sinai in New York and author of “Food Allergies: A Complete Guide to Eating When Your Life Depends on It." - Dr. Scott Sicherer, Elliot and Roslyn Jaffe Professorship in Pediatric Allergy and Immunology, Icahn School of Medicine at Mount Sinai Learn more: http://health.usnews.com/health-news/health-wellness/articles/2015/03/10/managing-food- allergies-5-surprising-new-approaches-to-prevention-diagnosis-and-treatment

The Wall Street Journal – March 9 What Autopsies Can Teach – Melinda Beck Medical mysteries lurk in every family, yet the autopsies that could reveal them have become increasingly rare. Some researchers hope alternative forms of postmortem investigations could increase interest. These include partial autopsies of individual organs, and virtual autopsies, which examine bodies with MRI or CT scans without dissecting them. Mount Sinai Health System in New York City plans to offer “minimally invasive” autopsies, which use very small instruments to remove targeted tissue samples for further study. Pathologists there hope this will be less costly and more acceptable to families than traditional open autopsies. - Mount Sinai Health System Learn more: http://www.wsj.com/articles/what-autopsies-can-teach-1425939927

Endocrine Web – March 9 CDC Survey Shows Age-Related Variability in Diabetes Management – Nere Onosode Younger adults with diabetes (age 18 to 39 years) are less likely than older patients to take medication to control their glucose levels or to see a doctor biannually, according to a National Health Interview Survey (NHIS) Data Brief. The report “tells us that [the percentage of] people seeking medical care is remarkably high after a diagnosis of diabetes is made, including care from foot and eye doctors, and that in the younger age group where the information might be more valuable for preventing problems, not enough people pay attention to blood pressure and cholesterol levels,” commented Gerald Bernstein, MD, FACP, Director, Diabetes Management Program, Mount Sinai Beth Israel. “This is a dramatic difference from what was seen a couple of decades ago when the number of people seeking care was much lower,” Dr. Bernstein said. -Dr. Gerald Bernstein, Associate Clinical Professor, Medicine, Endocrinology, Diabetes and Bone Disease, Icahn School of Medicine at Mount Sinai Learn more: http://www.endocrineweb.com/professional/diabetes-complications/cdc-survey-shows-age- related-variability-diabetes-management

HealthDay – March 9 Physically Tough Jobs May Harm a Man's Fertility: Study – Robert Preidt Hard physical work, high blood pressure and taking multiple medications are among the factors that may lower sperm quality and make men less fertile, new research finds. Men who had been diagnosed with high blood pressure also had a lower percentage of normally shaped sperm than those without high blood pressure, the findings showed. Doron Stember, MD, is assistant professor of urology at the Icahn School of Medicine at Mount Sinai in New York City. He said that "diabetes, obesity and the metabolic syndrome have previously been associated with poor semen quality," and now high blood pressure can be added to that list. "The key message is that lifestyle factors, such as activity and diet, can play an important role for men seeking fertility," Stember said. - Dr. Doron Stember, Assistant Professor, Urology, Icahn School of Medicine at Mount Sinai Learn more: http://consumer.healthday.com/men-s-health-information-24/men-s-problems-health- news-469/tough-physical-work-may-harm-a-man-s-fertility-study-697222.html Additional Coverage: U.S. News & World Report: http://health.usnews.com/health-news/articles/2015/03/09/physically-tough- jobs-may-harm-a-mans-fertility-study

Forbes – March 9 Kiss Chapped Lips Goodbye – Celia Shatzman Like hat hair and dry cuticles, chapped lips are practically inescapable in the colder months. “The skin of the lips is thinner than normal skin and there are fewer oil glands in this area, so they can’t defend themselves against environmental strains as well as other parts of the body,” explains Joshua Zeichner, MD, Director of Cosmetic and Clinical Research in Dermatology at The Mount Sinai Hospital in New York City. Luckily, there are steps you can take to protect your pucker, starting with finding the right lip balm. - Dr. Joshua Zeichner, Assistant Professor, Dermatology, Icahn School of Medicine at Mount Sinai, Director, Cosmetic and Clinical Research in Dermatology, The Mount Sinai Hospital Learn more: http://www.forbes.com/sites/celiashatzman/2015/03/09/kiss-chapped-lips-goodbye/

Yahoo Health – March 9 Watch Yourself! Today Is One of the Most Dangerous Days of the Year – Jenna Birch What a difference just one hour makes. According to research, the Monday after we spring forward for daylight saving time results in more fatal car crashes, heart attacks and injuries in the workplace than at any other time of year. According to Steven Feinsilver, MD, director of the Center for Sleep Medicine at The Mount Sinai Hospital and a professor of Pulmonary, Critical Care and Sleep Medicine Division at Icahn School of Medicine at Mount Sinai, our busy lives are probably in part to blame for the uptick in incidents after the shift to daylight saving. “You have to start with the idea that we’re all a little sleep deprived to begin with,” Feinsilver tells Yahoo Health. “We know that sleep deprivation leads to a host of issues over the long-term, like an increase in heart attack risk, stroke and high blood pressure, and poor cognitive function in the short term.” -Dr. Steven Feinsilver, Professor, Medicine, Pulmonary, Critical Care and Sleep Medicine, Icahn School of Medicine at Mount Sinai, Director, Center for Sleep Medicine, The Mount Sinai Hospital Learn more: https://www.yahoo.com/health/watch-yourself-today-is-one-of-the-most-dangerous- 113172013917.html

Master & Dynamic – March 3 The Power of Music: Understanding Music Therapy at Mount Sinai Kravis Children’s Hospital Music is power. Whether in the foreground or the background, music has the ability to influence everything from how we feel to how fast we walk through the supermarket. It can shape our perception of our environment and on a physiological level, it can even affect how we experience pain. At Kravis Children’s Hospital at Mount Sinai, sound’s power is harnessed for clinical treatment. To better understand its effects on the brain as well as its use as integrative medical treatment, we caught up with Todd O’Connor, a music therapist, who works with children at Mount Sinai. - Todd O’Connor, Music Therapist, Kravis Children’s Hospital at Mount Sinai Learn more: http://blog.masterdynamic.com/article/music-therapy-mount-sinai-kravis-childrens- hospital

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: [email protected] on behalf of Lindo, Allisa Subject: Mount Sinai In The News - March 9, 2015 Date: Monday, March 09, 2015 11:21:08 AM Attachments: ATT00001.txt

In the News March 9, 2015

The New York Times – March 7 On the Case at Mount Sinai, It’s Dr. Data – Steve Lohr Jeffrey Hammerbacher is a number cruncher — a Harvard math major who went from a job as a Wall Street quant to a key role at Facebook to a founder of a successful data start-up. But five years ago, he was given a diagnosis of bipolar disorder, a crisis that fueled in him a fierce curiosity in medicine — about how the body and brain work and why they sometimes fail. The more he read and talked to experts, the more he became convinced that medicine needed people like him: skilled practitioners of data science who could guide scientific discovery and decision-making. Now Mr. Hammerbacher, 32, is on the faculty of the Icahn School of Medicine at Mount Sinai, despite the fact that he has no academic training in medicine or biology. He is there because the school has begun an ambitious, well-funded initiative to apply data science to medicine. Eric Schadt, the computational biologist who recruited Mr. Hammerbacher to Mount Sinai, says the goal is to transform medicine into an information science, where data and computing are marshaled to deliver breakthroughs in the treatment of cancer, Alzheimer’s, diabetes and other chronic diseases. -Jeff Hammerbacher, Assistant Professor, Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai - Dr. Eric Schadt, Professor, Chair, Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, Director Icahn Institute for Genomics and Multiscale Biology Learn more: http://www.nytimes.com/2015/03/08/technology/on-the-case-at-mount-sinai-its-dr- data.html?_r=0 Additional Coverage: The Times of India via The New York Times: http://timesofindia.indiatimes.com/tech/tech-news/On-the- case-at-Mount-Sinai-its-Dr-Data/articleshow/46498460.cms

HealthDay – March 8 A Sense of Purpose May Help Your Heart – Alan Mozes Living your life with a strong sense of purpose may lower your risk for early death, heart attack or stroke, new research suggests. The finding is based on a broad review of past research involving more than 137,000 people in all. "Psychosocial conditions such as depression, anxiety, chronic stress and social isolation have strong associations with heart disease and mortality," said study lead author Randy Cohen, MD, a cardiologist at Mount Sinai St. Luke's-Roosevelt Hospitals in New York City. - Dr. Randy Cohen, Medical Director, University Medical Practice Associates, Mount Sinai St. Luke’s Roosevelt Learn more: http://consumer.healthday.com/cardiovascular-health-information-20/heart-attack-news- 357/having-a-sense-of-purpose-may-help-your-heart-697193.html Additional Coverage: Medical Xpress: http://medicalxpress.com/news/2015-03-purpose-heart.html Phys.org: http://phys.org/wire-news/187113044/have-a-sense-of-purpose-in-life-it-may-protect-your- heart.html KTLA TV: No Web Link Available

Tech Times – March 8 Having a Goal in Life May Help Extend Lifespan – Dianne Depra Having a purpose in life has been linked with psychological well-being before. Researchers have now found that it also can also help extend lifespans by protecting the heart. In a study presented at the American Heart Association EPI/Lifestyle 2015 Sessions, researchers led by a team from Mount Sinai Roosevelt and Mount Sinai St. Luke's have determined that having a goal in life lowers risks of stroke and heart disease. "Our study shows there is a strong relationship between having a sense of purpose in life and protection from dying or having a cardiovascular event," said Randy Cohen, MD, lead author for the study and a preventive cardiologist at Mount Sinai. Alan Rozanski, MD, wellness and prevention programs director from The Mount Sinai Hospital, and a co-author for the study, said that their research should aid future studies in further assessing how important having a life purpose is as a factor that determines well-being and realizing the impact that it carries. - Dr. Randy Cohen, Medical Director, University Medical Practice Associates, Mount Sinai St. Luke’s Roosevelt - Dr. Alan Rozanski, Professor, Medicine, Cardiology, Icahn School of Medicine at Mount Sinai, Director, Wellness and Prevention Programs, The Mount Sinai Hospital Learn more: http://www.techtimes.com/articles/38096/20150308/having-a-goal-in-life-may-help-extend- lifespan.htm Additional Coverage: Medical Daily: http://www.medicaldaily.com/preserve-heart-health-having-purpose-life-324758 Business Standard: http://www.business-standard.com/article/pti-stories/high-sense-of-purpose-may- protect-your-heart-study-115030800495_1.html ND.nl (Netherlands): https://www.nd.nl/artikelen/2015/maart/09/levensdoel-beschermt-hart [Article is in Dutch] Il Giornale (Italy): http://salute.ilgiornale.it/news/21641/vita-senso--esistenza-propria/1.html [Article is in Italian] TGCOM24 (Italy): http://www.tgcom24.mediaset.it/salute/avere-uno-scopo-nella-vita-salva-il-cuore- rischio-infarto-ridotto-del-19-_2099580-201502a.shtml [Article is in Italian] ANSA (Italy): http://www.ansa.it/saluteebenessere/notizie/rubriche/medicina/2015/03/08/uno-scopo- nella-vita-salva-il-cuore-19-rischio-infarto_1098e5e3-39a4-4615-847f-2f85495d8ae5.html [Article is in Italian]

The Times of India – March 9 Highly Processed Foods Linked to Addictive Eating – Hemali Chhapia Shah A new study confirms what has long been suspected: highly processed foods like chocolate, pizza and French fries are among the most addictive. This is one of the first studies to examine specifically which foods may be implicated in "food addiction," which has become of growing interest to scientists and consumers in light of the obesity epidemic. Nicole Avena, assistant professor of pharmacology and systems therapeutics at Icahn School of Medicine at Mount Sinai in New York City, and a co-author on the study, explained the significance of the findings. "This is a first step towards identifying specific foods, and properties of foods, which can trigger this addictive response," she said. - Nicole Avena, PhD, Assistant Professor, Pharmacology and Systems Therapeutics, Icahn School of Medicine at Mount Sinai Learn more: http://timesofindia.indiatimes.com/Home/Science/Highly-processed-foods-linked-to- addictive-eating/articleshow/46503049.cms Additional Coverage: Informe21.com: http://informe21.com/dieta/las-pizzas-y-el-chocolate-crean-tanta-dependencia-como- las-drogas [Article is in Spanish] Entorno Inteligente: http://www.entornointeligente.com/articulo/5252505/La-pizza-y-el-chocolate-tan- adictivos-como-la-droga- [Article is in Spanish]

Healthline News – March 6 Better Late Than Never, Doctors Begin to Treat Obesity – Cameron Scott Last month, Christopher Ochner, PhD, a pediatrician at The Mount Sinai Hospital, and Adam Tsai, a Denver internist and obesity specialist, published an article in The Lancet making the case that doctors should start treating excess weight before patients develop diseases linked to obesity. The article argued that the science is settled: Obesity isn’t only or primarily caused by bad eating habits, and once set, it’s nearly impossible to undo with diet and exercise alone. Ochner and Tsai laid out some recommendations for how doctors could move progressively from noninvasive care like nutrition education up through medication and on to recommending bariatric surgery. The response from other doctors was mixed, but included remarks like, “You’re just giving people excuses to be lazy,” and, “You’re taking personal responsibility out of it,” Ochner told Healthline. -Christopher Ochner, PhD, Assistant Professor, Pediatrics, Adolescent Medicine, Psychiatry, Icahn School of Medicine at Mount Sinai Learn more: http://www.healthline.com/health-news/doctors-begin-to-treat-obesity-030615

Medpage Today – March 6 Obeying Court Order, FDA Revamps Tobacco Panel – Shannon Firth Four members of its Tobacco Products Scientific Advisory Committee (TPSAC) were dismissed or have resigned, the FDA said, following a federal court decision last year that they were too cozy with anti- tobacco interests. Rosamond Rhodes, PhD, professor of medical education and director of bioethics education at the Icahn School of Medicine at Mount Sinai, in New York City, said that conflicts of interests have been demonstrated in multiple studies and are common in research fields. "In medical centers, in places that have allowed drug representatives to provide pizza lunches or give out pens, the prescribing patterns are very different from institutions that don't allow it," Rhodes said. - Rosamond Rhodes, PhD, Professor, Medical Education, Director, Bioethics Education, Icahn School of Medicine at Mount Sinai Learn more: http://www.medpagetoday.com/Washington-Watch/FDAGeneral/50357

Healio – March 6 Endocrine Factors Influence Breast Cancer Therapy In this video exclusive, Derek LeRoith, MD, PhD, professor of medicine at Icahn School of Medicine at Mount Sinai in New York, discusses how triple negative breast cancer is particularly unresponsive to the usual forms of therapy. LeRoith also discusses study findings being presented at the meeting that have shown that black women tend to present with more advanced forms of breast cancer compared with white women. This may be due in part to the patient’s ability to seek care, according to LeRoith. - Dr. Derek LeRoith, Professor, Medicine, Endocrinology, Diabetes and Bone Disease, Icahn School of Medicine at Mount Sinai Learn more: http://www.healio.com/endocrinology/practice-management/news/online/%7Be9c5ad35- cb48-48ae-ad40-ef21ffe4ad01%7D/video-endocrine-factors-influence-breast-cancer-therapy

Times Ledger – March 8 Mount Sinai Queens Opens a Center for Cancer Treatment – Bill Parry Mount Sinai Queens opened a new medical facility which treats cancer and blood disorders as part of a $125 million expansion. Community leaders, elected officials and the hospital’s administration held a ribbon-cutting ceremony at the Mount Sinai Queens Infusion Center last Friday, across the street from the main hospital, at 25-10 30th Ave. in Astoria. “When it comes to providing comprehensive outpatient cancer care, Mount Sinai is second to none,” Mount Sinai Queens Executive Director Caryn Schwab said. “Our new center fills a need for the community by bringing together as many cutting-edge cancer treatments available in one, easy-to-access location,” Howard Greenberg, MD, the director of the Mount Sinai Infusion Center, said. -Caryn Schwab, Executive Director, Mount Sinai Queens -Dr. Howard Greenberg, Assistant Professor, Medicine, Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, Director, the Mount Sinai Queens Infusion Center - Dr. Che-Kai Tsao, Assistant Professor, Medicine, Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai Learn more: http://www.timesledger.com/stories/2015/10/mtsinai_tl_2015_03_06_q.html

WCBS TV – March 8 Canned Oxygen: Latest Craze to Keep You Energized – Max Gomez You have heard of energy drinks and flavored water but how about flavored oxygen? This is the latest craze some believe will leave you feeling renewed and reenergized but it is a pricey way to get a breath of fresh air. The canned oxygen is promoted for recreational use only to supposedly ease altitude sickness, headaches and jetlag, and to reboot after aerobics workout, and some claim, after a tough night out. Neurologist, Mark Green, MD, at The Mount Sinai Hospital says, “The evidence is fairly weak. Even if the effect occurs, it tends to be short-lived because there is not very much oxygen in these containers.” - Dr. Mark Green, Professor, Neurology, Headache, Anesthesiology, Rehabilitation Medicine, Icahn School of Medicine at Mount Sinai Learn more: http://newyork.cbslocal.com/video/11207374-canned-oxygen-latest-craze-to-keep-you- energized/

Beauty High – March 6 The Deal on Hyaluronic Acid and What It Does For Your Skin – Victoria Moorhouse Lately, we’ve been seeing a certain ingredient pop up on the formulation lists of many, many moisturizers that’s worked up a reputation for being a showstopper in giving your skin a healthy hydration balance. It’s called hyaluronic acid. It makes sense that we’re seeing so many hyaluronic acid mentions, as the product works to pull in moisture to your skin. Heidi Waldorf, MD, Director of Laser and Cosmetic Dermatology at The Mount Sinai Hospital in New York City, explains that the ingredient is what is classified as a humectant when it is placed in skin care products. What’s this, you ask? “That means it pulls in moisture from the environment and the deeper skin below into the outer stratum corneum,” says Dr. Waldorf. - Dr. Heidi Waldorf, Associate Clinical Professor, Dermatology, Icahn School of Medicine at Mount Sinai, Director, Laser and Cosmetic Dermatology, The Mount Sinai Hospital Learn more: http://beautyhigh.com/hyaluronic-acid-and-skin-care/

Plastic Surgery Practice – February 26 The Eyes: Bespoke Solutions For Treating Undereye Bags – Denise Mann Undereye bags, dark circles, and pronounced puffiness: These rank high among the reasons that patients visit a dermatologist or cosmetic surgeon each year. Ask a handful of doctors how they treat undereye bags, and you will get handful of answers—and that’s exactly what we did. “Two decades ago, I would have referred these patients out to my surgical colleagues for a lower lid blepharoplasty. However, advances in our understanding of the anatomic changes of aging and in the products and procedures available have allowed for safe, effective noninvasive alternatives,” says Heidi Waldorf, MD, an associate clinical professor of dermatology at the Icahn School of Medicine at Mount Sinai. - Dr. Heidi Waldorf, Associate Clinical Professor, Dermatology, Icahn School of Medicine at Mount Sinai, Director, Laser and Cosmetic Dermatology, The Mount Sinai Hospital Learn more: http://www.plasticsurgerypractice.com/2015/02/eyes-bespoke-solutions-treating-eye-bags/

The New York Daily News – March 8 Breastfeeding is the gold standard of nutrition for infants, says Dr. Erica Brody of Mount Sinai – Katie Charles Not everyone has the same comfort level with breastfeeding in public — online forums don’t seem to tire of this debate — but the science proving the health benefits of breastfeeding is crystal clear. “Breastfeeding has benefits for the infant, the mom, and the planet on the whole,” says the director of pediatric breastfeeding medicine at The Mount Sinai Hospital, Erica Brody, MD. She continues, “The numbers show that breastfeeding helps infants have fewer infections, and lowers both the infant and mother’s their risk of future health problems including diabetes and heart disease. And because breastfeeding is free and causes no waste, it saves a lot of money for the country and the planet.” - Dr. Erica Brody, Assistant Professor, Pediatrics, Pediatrics Associates, Icahn School of Medicine at Mount Sinai, Director, Pediatric Breastfeeding Medicine, Kravis Children’s Hospital at The Mount Sinai Hospital Learn more: http://www.nydailynews.com/life-style/health/breastfeeding-gold-standard-infant- nutrition-article-1.2134751

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: [email protected] on behalf of MountSinaiNewsNow Subject: Mount Sinai In The News - March 6, 2015 Date: Friday, March 06, 2015 12:11:31 PM Attachments: ATT00001.txt

In the News March 6, 2015

Multiple Sclerosis News Today – March 6 Multiple Sclerosis Damage May be Prevented by Novel Molecules – Alisa Woods, PhD Researchers at the Icahn School of Medicine at Mount Sinai have identified new compounds that could protect from multiple sclerosis related damage, based on studies in mice with nervous system damage, mimicking MS. The study appeared in the journal Nature Neuroscience. Jeffery Haines, PhD, a post- doctoral fellow at Mount Sinai and the study’s lead author commented, “The compounds identified in this study, when administered orally, both reduced the inflammation that is a hallmark of multiple sclerosis and protected against the nerve cell damage seen in mouse models of the disease.” Patrizia Casaccia, MD, PhD, Professor of Neuroscience, Genetics and Genomic Sciences at Mount Sinai and senior author of the study noted, “The study results elucidate the molecular mechanisms underlying disease progression in multiple sclerosis models, providing a basis for future clinical trials to determine safety and efficacy of these chemical agents in humans with demyelinating disorders.” - Jeffrey Haines, PhD, Postdoctoral Fellow, Neuroscience, Icahn School of Medicine at Mount Sinai - Dr. Patrizia Casaccia, Professor, Neuroscience, Genetics and Genomic Science, Neurology, Icahn School of Medicine at Mount Sinai, Chief, the Center of Excellence for Myelin Repair, the Friedman Brain Institute at Mount Sinai Learn more: http://multiplesclerosisnewstoday.com/2015/03/06/multiple-sclerosis-damage-may-be- prevented-by-novel-molecules/

Doctors Lounge via HealthDay – March 5 Study Examines Palliative Care in Cardiac Intensive Care Units – David Templeton Increased palliative care education and training among clinicians who are involved in cardiac critical care could benefit care, according to a study published in the March 1 issue of The American Journal of Cardiology. Tara Naib, MD, MPH, from the Icahn School of Medicine at Mount Sinai in New York City, and colleagues examined the role of palliative care in cardiac intensive care units (CICUs). Data were included for 1,368 patients admitted from Jan. 1 through Dec. 31, 2012. - Dr. Tara Naib, Assistant Professor, Medicine, Cardiology, Icahn School of Medicine at Mount Sinai Learn more: http://www.doctorslounge.com/index.php/news/pb/53508 Additional Coverage: Medical Xpress: http://medicalxpress.com/news/2015-03-palliative-cardiac-intensive.html

Pittsburgh Post-Gazette – March 5 Evidence Points to Link between Phthalates, Male Sexual Development – David Templeton They’re used in perfume, soap, shampoo and skin moisturizers. You’ll find them in flexible plastic and vinyl toys, shower curtains, plastic plumbing pipes, vinyl flooring, wood finishes, detergents, wallpaper and hundreds of other products. They’re called phthalates, and a University of Pittsburgh scientist announced studies this week that link these chemicals to disruptions in an important pregnancy hormone necessary for proper masculinization of male genitalia in fetuses. The findings build on an Icahn School of Medicine at Mount Sinai study published last month in the journal Human Reproduction, which detailed how phthalates target hCG in the placenta, with measurable impacts in the mother’s blood throughout pregnancy. - Icahn School of Medicine at Mount Sinai Learn more: http://www.post-gazette.com/news/science/2015/03/05/Evidence-points-to-link-between- phthalates-and-birth-defects/stories/201503050196 Additional Coverage: Health Canal: http://www.healthcanal.com/pregnancy-childbirth/60986-pervasive-chemical-potentially- alters-levels-of-a-pregnancy-hormone-that-influences-sex-development.html Pourquoi Docteur (France): http://www.pourquoidocteur.fr/Les-phtalates-perturbent-le-developpement- genital-du-foetus-10007.html [Article is in French] Connecticut News: http://blog.ctnews.com/kantrowitz/2015/03/06/phthalates-potentially-alter-levels-of- a-pregnancy-hormone-that-influences-sex-development/

Crain’s Health Pulse – March 6 Health Reform: 'The Challenge of Moving to Scale So Quickly' As the New York health care industry heads to the home stretch in wrapping up DSRIP applications, attention is shifting to implementation. At an event sponsored by the New York eHealth Collaborative, a panel considered DSRIP’s next phase. The first impression: DSRIP is huge. Jordanna Davis, a principal of the Sachs Policy Group (and daughter of Mount Sinai President and Chief Executive Kenneth Davis, MD), noted Advocate Community Partners has an attribution of 769,089, while HHC has 634,789. “These are huge,” she said. “Everyone has got to do very well, and we have a lot of eggs in a few baskets.” Ms. Davis asked panelist Arthur Gianelli, MD, president of Mount Sinai St. Luke’s, whether that concentration of so many lives in a few PPSs was frightening. “Yes, that will be a real challenge,” he answered. “We should not underestimate the challenge of moving to scale so quickly.” - Dr. Arthur Gianelli, Lecturer, Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, President, Mount Sinai St. Luke’s Learn more: http://www.crainsnewyork.com/article/20150306/PULSE/150309906/health-reform-the- challenge-of-moving-to-scale-so-quickly#

The Wall Street Journal – March 5 Get Ready, Get Set, Spring Forward – Corinne Ramey At 2 a.m. Sunday, when we set our clocks forward an hour—or, alternatively, when our gadgets do it for us—we’ll be carrying out a historically controversial policy, formerly beloved by New York City and despised by New York state. While the time changes just an hour, businesses from hospitals to coffee shops to farms will feel the transitional effects of one 23-hour day. At The Mount Sinai Hospital, the time change is more complicated in the fall, when, for example, nurses must mark if a medication was given at the first 1:15 a.m. or the second, said Bruce Darrow, MD, the hospital’s chief medical information officer. - Dr. Bruce Darrow, Associate Professor, Medicine, Cardiology, Icahn School of Medicine at Mount Sinai, Chief Medical Information Officer, The Mount Sinai Hospital Learn more: http://www.wsj.com/articles/get-ready-get-set-spring-forward-1425605273

Crain’s Health Pulse – March 6 At a Glance: Who’s News Mount Sinai Beth Israel named Dr. Ira Jacobson as chairman of the Department of Medicine. Previously, Dr. Jacobson, who specializes in hepatology and liver disease, was chief of the Division of Gastroenterology and Hepatology at Weill Cornell Medical College. - Dr. Ira Jacobson, Senior Faculty, Medicine, Chair, Department of Medicine, Mount Sinai Beth Israel Learn more: http://www.crainsnewyork.com/article/20150306/PULSE/150309906/health-reform-the- challenge-of-moving-to-scale-so-quickly#

New York Magazine – March 3 What a Neuroscientist Said About Eminem’s Brain – Claire Landsbaum Eminem may not have known this when he wrote it, but his line about getting along with the voices inside his head is strangely apt. According to psychologist Scott Barry Kaufman, the brains of creative geniuses and people with schizophrenia are similar in surprising ways. They both have an extremely active precuneus, or area that facilitates daydreaming and free association. On Sunday, as part of the 92nd Street Y's Seven Days of Genius series, Kaufman, along with neuroscientist Heather Berlin, PhD, and science rapper Baba Brinkman, discussed the neuroscience of creativity. "He probably has more advanced connections in terms of his language areas. Over time, when you practice something, a cognitive skill or a motor skill, you’re developing connections in the brain. So I’m sure his brain would look slightly different," said Berlin. - Heather Berlin, PhD, Assistant Professor, Psychiatry, Neuroscience, Icahn School of Medicine at Mount Sinai Learn more: http://nymag.com/scienceofus/2015/03/what-a-neuroscientist-said-about-eminems- brain.html

TCTMD – March 5 ED Protocol for Acute Chest Pain Patients Reduces Cardiac Testing, Doubles Early Discharge – Yael L. Maxwell A protocol called the HEART Pathway safely and effectively identifies patients presenting to the emergency department (ED) with acute chest pain who can safely be sent home early, according to single-center study published online March 3, 2015, ahead of print in Circulation: Cardiovascular Quality and Outcomes. In a telephone interview with TCTMD, Samin K. Sharma, MD, of The Mount Sinai Hospital (New York, NY), said he would advocate the use of this protocol, especially because the simple application of any protocol “always results in positive [outcomes]. “The strength of the Pathway is that [practice] becomes more generalized, so that it is consistent and there is very little room for individuality,” he continued. “Of course, you can always change things, but everyone is thinking the same way.” - Dr. Samin Sharma, Professor, Medicine, Cardiology, Dean of International Clinical Affiliations, Icahn School of Medicine at Mount Sinai Learn more: http://www.tctmd.com/show.aspx?id=128156

Anesthesiology News – March 2015 Anesthesiologists Must Strive to Improve Infection Control It is important for those in the anesthesiology community to work together to improve infection control practices and to prevent the occurrence of infections linked to the practice of anesthesiology. That was the message from a session held at the recent New York State Society of Anesthesiologists’ (NYSSA) 68th Annual PostGraduate Assembly (PGA) in Anesthesiology. Indeed, according to Amanda Rhee, MD, assistant professor of anesthesiology, Icahn School of Medicine at Mount Sinai in New York City, hand hygiene has to be a fundamental component of any infection control program designed to reduce the incidence of surgical site infections (SSIs). At her institution, for example, researchers cultured the hands of anesthesia professionals to demonstrate the level of contaminants and “gain their buy-in” to the program. Her team has also posted signs throughout the surgical section touting the message “foam in, foam out,” which reminds providers to wash their hands every time they enter and leave the room. Hygiene dispensers are conveniently located inside and outside the doors to every room in the section. - Dr. Amanda Rhee, Assistant Professor, Anesthesiology, Icahn School of Medicine at Mount Sinai Learn more: http://www.anesthesiologynews.com/ViewArticle.aspx? d=Clinical%2BAnesthesiology&d_id=1&i=March+2015&i_id=1156&a_id=29642

Queens Chronicle – March 5 Queens Gets More Modern Cancer Care – Cristina Schreil With the official opening of a revamped infusion center on 30th Avenue in Astoria, Mount Sinai Queens hopes to bring 21st-century cancer medicine to “this side of the river.” A ribbon-cutting ceremony last Friday celebrated recently installed state-of-the-art amenities at the Mount Sinai Infusion Center, an extension of the Tisch Cancer Institute at the hospital. Howard Greenberg, MD, a doctor and director of the center, said the facility serves around 30 to 40 Western Queens-based patients — residing in neighborhoods as far as East Elmhurst — five days a week. “The center enables me and my associates … to provide the level of care usually seen in large tertiary cancer centers like the one across the water. That care is now available in this community,” he said. Luis Isola, MD, professor of medicine, hematology and oncology at the Icahn School of Medicine at Mount Sinai, said the center integrates into a larger vision of the hospital and he hopes it will be a new “epicenter” of health. -Caryn Schwab, Executive Director, Mount Sinai Queens -Dr. Howard Greenberg, Assistant Professor, Medicine, Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, Director, the Mount Sinai Queens Infusion Center - Dr. Luis Isola, Professor, Medicine, Hematology and Medical Oncology, Pediatrics, Icahn School of Medicine at Mount Sinai, Director, Cancer Care Programs, The Mount Sinai Health System Learn more: http://www.qchron.com/editions/western/queens-gets-more-modern-cancer- care/article_8f2906ac-e7b2-5a07-850d-656e608979f6.html

Main St – March 6 Adult Children's Applications for Guardianship Do Not Guarantee Justice for the Elderly – Juliette Fairley By the time my 80-year-old father, James Fairley, boarded a flight to New York City in October 2014, the probate court in Bexar County had dismissed my guardianship application. That's not surprising given the fact that some 37% of judges, court managers and clerks who responded to a Center for Elders and the Courts survey revealed that guardianship filings have increased over the last three years and 43% noted an increase in caseloads. Once my father was safely settled in my comfortable Manhattan apartment, I set up appointments for him with specialists. We subsequently visited Cardiologist Nicholas DuBois, MD, of The Mount Sinai Hospital, who updated my father’s blood pressure medication. Within six weeks of living with me, my father was back to his normal happy self with a healthy appetite and positive outlook on life. - Dr. Nicholas DuBois, Senior Faculty, Medicine, Cardiology, Icahn School of Medicine at Mount Sinai Learn more: http://www.mainstreet.com/article/adult-childrens-applications-for-guardianship-do-not- guarantee-justice-for-the-elderly

Yahoo Finance – March 5 Why Nearly 200,000 Of These Good-Paying Jobs Will Go Unfilled – Joanna Campione America, we need more nurses. By 2020, the U.S. economy will create an estimated 1.6 million jobs in nursing. But hospitals and care facilities will be short 193,000 nurses to fill those positions. Bobby Matthews, who handles talent acquisition and retention for the Mount Sinai Health System in New York, says the Affordable Care Act has put emphasis back on preventive care. “As care moves from less of an in-patient focus to more of an out-patient focus,” he says, “we’re going to have a higher need for things like clinical coordinators, patient navigators, nurses that are educated in the community so they are never admitted to the hospital to begin with.” - Bobby Matthews, Talent Acquisition and Retention, Mount Sinai Health System - Zhanna Khandros, RN, Cardiology, The Mount Sinai Hospital Learn more: http://finance.yahoo.com/news/by-2020--u-s--will-have-1-6-million-job-openings-in-this- field-194415742.html

Health News Digest – March 4 Tips for Preventing Kidney Stones March is Kidney Awareness month, and physicians from the Mount Sinai Health System are available to discuss risk factors associated with kidney stones and ways to prevent them. "About one in ten Americans will develop a kidney stone at some point," said John Cijiang He, MD, PhD, Professor of Pharmacology and Systems Therapeutics and Chief, Division of Nephrology at the Icahn School of Medicine at Mount Sinai. "Kidney stones can be extremely painful, and in some cases, can lead to complications including urinary tract infection or even kidney damage," said Shuchita Sharma, MD, Clinical Nephrologist at the Icahn School of Medicine. - Dr. John Ci-jiang He, Professor, Medicine, Nephrology, Pharmacology and Systems Therapeutics, Chief, Division of Nephrology, Icahn School of Medicine at Mount Sinai - Dr. Shuchita Sharma, Instructor, Medicine, Nephrology, Icahn School of Medicine Learn more: http://www.healthnewsdigest.com/news/Health_Tips_620/Tips-for-Preventing- Kidney-Stones.shtml

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: [email protected] on behalf of MountSinaiNewsNow Subject: Mount Sinai In The News - March 5, 2015 Date: Thursday, March 05, 2015 11:58:07 AM Attachments: ATT00001.txt

In the News March 5, 2015

Genetic Engineering & Biotechnology News – March 5 Novel Sequencing Technique Developed for Mitochondria The cells energy production organelle is often taken for granted on a daily basis, supplying the cell with a pool of chemical energy molecules critical for normal metabolic function. However, this unique organelle plays major roles in signaling, differentiation, and cell death. Moreover, since it contains its own DNA, it has been frequently linked to an individuals inherited risk for diabetes, heart disease, and even cancer. Now, scientists at the Icahn School of Medicine at Mount Sinai have developed a powerful new tool they believe may assist researchers in explaining the disparity between individuals with bad health habits, some of whom get sick and those that do not. "Researchers have struggled to sequence mtDNA accurately and in a cost effective manner," explained Ravi Sachidanandam, PhD, assistant professor of oncological sciences at the Icahn School of Medicine at Mount Sinai and senior author on the current study. "The technique we have developed will allow us to identify dysfunction within mitochondria and makes mtDNA a useful biomarker as well as a potential therapeutic target in cancer and many inherited diseases." - Ravi Sachidanandam, Assistant Professor, Oncological Sciences, Icahn School of Medicine at Mount Sinai Learn more: http://www.genengnews.com/gen-news-highlights/novel-sequencing-technique- developed-for-mitochondria/81251000/ Additional Coverage: Medical Xpress: http://medicalxpress.com/news/2015-03-cell-powerhouse-sequencing-technology- deeper.html

The Today Show – March 5 Living with Multiple Sclerosis – Hoda Kotb and Kathie Lee Gifford It affects over 2 million people worldwide, most of them women. One of those women is Kate Milliken. In 2006, she was 35 years old and working as a video producer. Numbness in her hand, delay on the left side of her body and terrible fatigue led to a diagnosis of Multiple Sclerosis. But since then Kate got married, had two kids and runs her own video production company. She sits down with the Today Show to discuss her diagnosis alongside her doctor, Stephen Krieger, MD, a neurologist at The Corinne Goldsmith Dickinson Center for Multiple Sclerosis at The Mount Sinai Hospital. Kate has not had an episode in a number of years. Dr. Krieger attributes that to “a number of things. I think we have a dozen medicines now that are proven to treat relapsing remitting MS and prevent those relapses and protect the brain.” There are currently no treatments for the more advanced stages of MS but researchers are working on changing that. -Dr. Stephen Krieger, Associate Professor, Neurology, Icahn School of Medicine, Attending, The Corinne Goldsmith Dickinson Center for Multiple Sclerosis, The Mount Sinai Hospital Learn more: http://www.today.com/klgandhoda/how-mom-two-living-multiple-sclerosis-2D80531907

Queens Gazette – March 4 Mount Sinai Queens Infusion Center Dedicated Leadership from Mount Sinai Queens joined community representatives and elected officials to formally dedicate the Mount Sinai Queens Infusion Center on February 27 in Astoria, located at 27-15 30th Avenue. The center treats cancer and blood disorders and features private infusion bays, a nutrition station and a totally renovated state-of-the-art interior. “The Mount Sinai Queens Infusion Center epitomizes quality care and is an integral part of the Tisch Cancer Institute at Mount Sinai,” said Director of Cancer Care Programs for the Mount Sinai Health System, Luis Isola, MD. “When it comes to providing comprehensive, outpatient cancer care, Mount Sinai is second to none, and this newly renovated center is just the latest example of our commitment to patients and their families during the most difficult fight of their lives,” said Executive Director of Mount Sinai Queens, Caryn A. Schwab. “Our new center fills a need for the community by bringing together as many cutting-edge cancer treatments available in one, easy-to-access location,” said Director of the Mount Sinai Queens Infusion Center, Howard Greenberg, MD. -Caryn Schwab, Executive Director, Mount Sinai Queens - Judy Trilivas, Chief Operating Officer, Mount Sinai Queens - Dr. Luis Isola, Professor, Medicine, Hematology and Medical Oncology, Pediatrics, Icahn School of Medicine at Mount Sinai, Director, Cancer Care Programs, The Mount Sinai Health System -Dr. Howard Greenberg, Assistant Professor, Medicine, Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, Director, the Mount Sinai Queens Infusion Center Learn more: http://www.qgazette.com/news/2015-03- 04/Features/Mount_Sinai_Queens_Infusion_Center_Dedicated.html

CBS News – March 4 With A Lick And A Nuzzle, Therapy Dogs Help Cancer Patients Heal Doctors have long suspected that the bond between people and animals can have healing powers. Now they have scientific proof. Researchers at Mount Sinai Beth Israel in New York conducted a study of the impact certified therapy dogs have on cancer patients. They discovered that when patients spent time with a therapy dog during chemo and radiation treatment, their emotional well-being and quality of life showed measurable improvement. - Mount Sinai Beth Israel Learn more: http://www.cbsnews.com/news/therapy-dogs-help-cancer-patients-heal/

AIDS Map – March 4 Smoking is the Biggest Risk Factor for Non-AIDS-Defining Cancers in People Living with HIV – Theo Smart Smoking appears to contribute most to the burden of non-AIDS-defining cancers diagnosed in people living with HIV in the US, out of all the potential modifiable risk factors. As noted by other presenters at the conference, the risk of AIDS-defining cancers is greatly elevated in people living with HIV, although these cancers have become less common since the introduction of antiretroviral therapy (ART). However, the risk of certain other types of cancer is also elevated, and may be increasing among people with HIV – particularly as they live to older ages on effective HIV treatment. For instance, a presentation by Keith Sigel of the Icahn School of Medicine at Mount Sinai looked specifically at the association between HIV- related immune suppression and lung cancer over two years in a cohort of 26,065 US veterans living with HIV from the Veterans Aging Cohort Study (VACS). This study found that having an average CD4 cell count (over the 24-month period) below 200 cells/mm3 was associated with a 70% greater risk of lung cancer, and having a CD4 count between 200 and 500 cells/mm3 was associated with a 30% increased risk compared to people living with HIV who had CD4 cell counts above 500 cells/mm3. - Dr. Keith Sigel, Assistant Professor, Medicine, General Internal Medicine, Icahn School of Medicine at Mount Sinai Learn more: http://www.aidsmap.com/Smoking-is-the-biggest-risk-factor-for-non-AIDS-defining- cancers-in-people-living-with-HIV/page/2950752/

CBS This Morning – March 4 FDA Warns Against "Keepsake" Ultrasounds There is no doubt that ultrasounds provide doctors with vital information about the condition of an unborn child. As the images get clearer -- and three dimensional -- more and more women are getting optional "keepsake" ultrasounds. But more time, and multiple visits, are part of what concerns the FDA and some doctors. While ultrasounds are considered safe, they are known to raise the temperature of exposed tissue, and can even create small bubbles known as cavitation. "I know that they are exciting, but I don't think women should abuse the medical technology for their entertainment purposes," board- certified OBGYN Rebecca Brightman, MD, said. - Dr. Rebecca Brightman, Assistant Clinical Professor, Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai Learn more: http://www.cbsnews.com/news/3-d-ultrasounds-cause-concern-for-obgyn-doctors-and- fda/

HealthDay – March 4 Medical Bills another Burden for Eczema Patients: Study – Robert Preidt Eczema isn't just a painful, chronic problem for many -- it's a big drain on the pocketbook, too, a new study finds. That finding didn't surprise dermatologists. Andrew Alexis, MD, is chair of the department of dermatology at Mount Sinai St. Luke's and Mount Sinai Roosevelt Hospitals in New York City. He said the study "highlights the health and economic burden of eczema in adults in the U.S. ... demonstrating increased sick days, higher health care utilization, and substantial costs associated with adult eczema." - Dr. Andrew Alexis, Associate Professor, Dermatology, Chair, Department of Dermatology, Mount Sinai St. Luke’s and Roosevelt Learn more: http://consumer.healthday.com/diseases-and-conditions-information-37/eczema-news- 618/medical-bills-another-burden-for-eczema-patients-697068.html Additional Coverage: U.S. News & World Report: http://health.usnews.com/health-news/articles/2015/03/04/medical-bills- another-burden-for-eczema-patients-study

Mother Jones – March 4 Why You Should Stop Eating Breakfast, Lunch, and Dinner – Kiera Butler A 2012 study that mice consuming all of their calories within an eight-hour window were less likely to develop metabolic diseases like diabetes than those who ate whenever they pleased. So should you quit meals and fast intermittently instead? You could try it. Christopher Ochner, PhD, a weight loss and nutrition expert at The Mount Sinai Hospital in New York, notes that there's no one-size-fits-all solution: Some people do well eating all their calories at once; others prefer to split them into snack-size portions. Instead of obsessing about meal size and frequency, Ochner recommends something simpler: Don't eat when it's time for a meal; eat when you feel hungry. -Christopher Ochner, PhD, Assistant Professor, Pediatrics, Adolescent Medicine, Psychiatry, Icahn School of Medicine at Mount Sinai Learn more: http://www.motherjones.com/environment/2015/03/against-meals-breakfast-lunch-dinner

Allure – March 4 Are You Suffering From Tech Neck? – Irma Elezovic Put down the screen. Your never-ending Instagram scrolls during your morning commute may cause you to age more quickly. Some call it ‘tech neck’; others call it ‘text neck.’ Either way, it’s a problem for the iPhone 6 generation. “The skin of the neck is sensitive and thin compared to other parts of the body,” says dermatologist Joshua Zeichner, MD. “Combine that with gravity and the constant craning over smartphones, and it’s an area uniquely at risk for fine lines and sagging.” - Dr. Joshua Zeichner, Assistant Professor, Dermatology, Icahn School of Medicine at Mount Sinai Learn more: http://www.allure.com/beauty-trends/blogs/daily-beauty-reporter/2015/03/tech-neck- texting-wrinkles.html

Refinery 29 – March 4 10 Skin Lies You Need To Stop Telling Lie: I’ve told you everything I’m using on my skin. This can be a lie of omission, but that doesn’t make it any less damaging. “The most important thing a patient can tell me is what she’s using on her skin,” says Joshua Zeichner, MD, director of cosmetic and clinical research in dermatology at The Mount Sinai Hospital in New York City. “If you’re not truthful about what you’re applying, I won’t be able to help you.” - Dr. Joshua Zeichner, Assistant Professor, Dermatology, Icahn School of Medicine at Mount Sinai, Director, Cosmetic and Clinical Research, Department of Dermatology, The Mount Sinai Hospital Learn more: http://www.refinery29.com/skin-care-myths#slide-1

Elle – February 26 I Accidentally, Finally Figured Out How to Get Rid of My Bumpy Skin – Victoria Dawson Hoff For as long as I can remember, smooth, mark-free arms and legs have been little more than a pipe dream. I, like many, have always suffered from keratosis pilaris, a physically painless but plenty embarrassing skin condition that manifests itself in large patches of rough red bumps all over my upper arms and thighs. KP is caused by a genetic inclination to produce too much keratin, causing hair follicles on the body to be clogged. While snowed in a few weeks ago, I decided to warm up in a bath with all the works. When I realized I was out of bath oils, I spied my trusty bottle of Moroccanoil and dumped a few glugs in the bathwater. A few hours later I absentmindedly ran my hand up my arm and realized with amazement that I was 100 percent bump free. Ever determined to play beauty detective, I then turned to doctors Gary Goldenberg, MD, and Joshua Zeichner, MD, both practicing dermatologists with The Mount Sinai Hospital in New York. They both agree that the presence of argan oil is probably largely responsible. - Dr. Joshua Zeichner, Assistant Professor, Dermatology, Icahn School of Medicine at Mount Sinai, Director, Cosmetic and Clinical Research, Department of Dermatology, The Mount Sinai Hospital - Dr. Gary Goldenberg, Assistant Professor, Dermatology, Pathology, Icahn School of Medicine at Mount Sinai Learn more: http://www.elle.com/beauty/makeup-skin-care/advice/a27002/keratosis-pilaris-bumpy- skin-cure/

Elle – March 2 Why We Recommend Putting Cactus All Over Your Face – Victoria Dawson Hoff Cactus seed oil—which also goes by prickly pear seed oil and barbary fig seed oil—contains larger doses of the very same vitamins and antioxidants that make Argan oil so great. This includes large amounts of linoleic acid (a fatty acid that is essential in stimulating healthy cell production and turnover), as well as vitamin E (which provides protection and helps skin retain moisture), and flavonoids, which are anti- inflammatory. Cactus oil is light and absorbs well, while providing a huge kick of moisture to skin cells. And all of this, of course, bodes well for keeping our complexions looking young. "It soothes, hydrates, and reduces inflammation that damages collagen, explaining why it's used to prevent skin aging," confirms Joshua Zeichner, MD, dermatologist at The Mount Sinai Hospital in New York City. - Dr. Joshua Zeichner, Assistant Professor, Dermatology, Icahn School of Medicine at Mount Sinai, Director, Cosmetic and Clinical Research, Department of Dermatology, The Mount Sinai Hospital Learn more: http://www.elle.com/beauty/makeup-skin-care/news/a27040/cactus-oil-for-skin/

Queens Gazette – March 5 Learning to Eat Healthily Rocco Sacramone, popular chef and owner of Astoria’s Trattoria L’incontro teamed up with Mount Sinai Queens and the United Community Civic Association (UCCA) on February 25 in recognition of American Heart Month for a cooking and tasting event at Central Sushi Bar and Lounge in Astoria. More than 400 guests were able to sample heart-healthy dishes that promote positive eating for good cardiovascular health, including gluten-free pasta made with vegetables. “We are so excited that Rocco of L’incontro can help our community learn about the value of healthy eating,” said Mount Sinai Queens Senior Director of Marketing and Communications Shelly Felder. -Shelly Felder, Senior Director of Marketing and Communications, Mount Sinai Queens -Marie Keogh, MPH, RD, CDN, Outpatient Dietitian, Mount Sinai Queens -Ana M. Rodriguez, Community Relations and Volunteer Services Director, Mount Sinai Queens Learn more: http://www.qgazette.com/news/2015-03-04/Features/Learning_To_Eat_Healthy.html

Wrestling Inc – March 4 The Rock's Rock Bottom To Jason Statham, Paige Visits Children's Hospital, New WWE Network Shows – Marc Middleton Paige visited Kravis Children's Hospital at Mount Sinai last Friday. Below are photos from her visit. - Kravis Children’s Hospital at Mount Sinai Learn more: http://www.wrestlinginc.com/wi/news/2015/0304/590025/the-rock-rock-bottom-to-jason- statham/

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: [email protected] on behalf of Lindo, Allisa Subject: Mount Sinai In The News - March 4, 2015 Date: Wednesday, March 04, 2015 12:03:41 PM Attachments: ATT00001.txt

In the News March 4, 2015

Runner’s World – March 3 Study Finds That Highly Processed Foods Are the Most Addictive – Alison Wade A new study, recently published by PLoS ONE, supports what many people have observed firsthand— that highly-processed foods with added fat and/or refined carbohydrates are most likely lead to addictive eating. The research team also found that foods with high glycemic loads were particularly likely to cause problems for those prone to addictive eating behavior. "This is a first step towards identifying specific foods, and properties of foods, which can trigger this addictive response," said Nicole Avena, PhD, a professor at Icahn School of Medicine at Mount Sinai and one of the study’s co-authors. - Nicole Avena, PhD, Assistant Professor, Pharmacology and Systems Therapeutics, Icahn School of Medicine at Mount Sinai Learn more: http://www.runnersworld.com/nutrition-for-runners/study-finds-that-highly-processed- foods-are-the-most-addictive

Environmental Health Perspectives – March 2015 Children’s Health in Latin America: The Influence of Environmental Exposures – Philip Landrigan, MD et al To control environmental threats to children’s health in Latin America, the World Health Organization (WHO), including the Pan American Health Organization (PAHO), will focus on the most highly prevalent and serious hazards—indoor and outdoor air pollution, water pollution, and toxic chemicals. Strategies for controlling these hazards include developing tracking data on regional trends in children’s environmental health (CEH), building a network of Collaborating Centers, promoting biomedical research in CEH, building regional capacity, supporting development of evidence-based prevention policies, studying the economic costs of chronic diseases in children, and developing platforms for dialogue with relevant stakeholders. - Dr. Philip Landrigan, Professor and System Chair, Preventative Medicine, Professor, Pediatrics, Dean for Global Health, Icahn School of Medicine at Mount Sinai Learn more: http://ehp.niehs.nih.gov/1408292/

Environmental Health Perspectives – March 2015 Jenny Pronczuk de Garbino: A Global Champion for Children’s Health – Philip Landrigan, MD and William Suk, MD On 20 September 2010, the children of the world, and all of us who work in children’s environmental health and pediatric toxicology, lost a beloved friend and global champion with the untimely death of Jenny Pronczuk de Garbino at 63 years of age. Pronczuk was a physician and, for many years, a medical officer in the Department of Public Health and Environment of the World Health Organization (WHO). She was the founder and, for more than a decade, the charismatic and inspirational leader of the WHO Initiative in Children’s Environmental Health. Her work improved the lives of children in all regions of the world. - Dr. Philip Landrigan, Professor and System Chair, Preventative Medicine, Professor, Pediatrics, Dean for Global Health, Icahn School of Medicine at Mount Sinai Learn more: http://ehp.niehs.nih.gov/1408293/

The New York Times – March 2 Bruised Hip of Nets’ Teletovic Leads to Blood Clot Awareness – Andrew Keh During a game on Jan. 22 at the Los Angeles Clippers, Mirza Teletovic experienced shortness of breath that was worrying enough that he stopped playing and was taken to a hospital. Tests revealed blood clots in the arteries of his lungs, a potentially fatal condition. Alan Benvenisty, MD, a professor of vascular and transplant surgery at the Icahn School of Medicine at Mount Sinai in New York, said the work and travel routines of N.B.A. players could create environments in which the players were at a slightly higher risk. James McKinsey, MD, a surgeon at Mount Sinai Roosevelt, said dehydration, in a minor way, could increase the thickness of a person’s blood, making it more susceptible to clotting. David Forsh, MD, chief of orthopedic trauma at Icahn, guessed that N.B.A. players, given their good physical condition, were at a lower risk for blood clots over all. But he noted that injuries and operations in the lower body were known to put patients at a higher risk for deep vein thrombosis. - Dr. James McKinsey, Vice Chair, Department of Surgery, Mount Sinai Roosevelt, Chief of Complex Aortic Interventions, Mount Sinai Health System - Dr. Alan Benvenisty, Professor, Surgery, Icahn School of Medicine at Mount Sinai - Dr. David Forsh, Assistant Professor, Orthopaedics, Icahn School of Medicine at Mount Sinai Learn more: http://www.nytimes.com/2015/03/03/sports/basketball/bruised-hip-of-nets-teletovic-leads- to-blood-clot-awareness.html?_r=0

Healthday – March 3 About 7 Percent of Kids Worldwide Have ADHD: Study – Dennis Thompson About 7 percent of children worldwide have attention-deficit/hyperactivity disorder (ADHD), new research concludes. This estimate -- which differs significantly from other recent appraisals -- is based on data from 175 prior studies conducted over nearly four decades. Critics say there may be serious problems with the way the researchers came to their conclusions, noting the research pools together dozens of studies that used a wide variety of criteria to determine whether children had ADHD. For example, the study pools prior results based on diagnostic criteria that varied among three versions of the Diagnostic and Statistical Manual of Mental Disorders, the "bible" used by mental health professionals, said Eyal Shemesh, MD, chief of behavioral and developmental health at the Kravis Children's Hospital at Mount Sinai in New York City. - Dr. Eyal Shemesh, Associate Professor, Pediatrics, Behavioral Pediatrics, Psychiatry, Icahn School of Medicine at Mount Sinai, Chief, Behavioral and Developmental Health, Kravis Children’s Hospital at Mount Sinai Learn more: http://consumer.healthday.com/kids-health-information-23/attention-deficit-disorder- adhd-news-50/about-7-percent-of-kids-have-adhd-worldwide-study-696948.html Additional Coverage: U.S. News & World Report: http://health.usnews.com/health-news/articles/2015/03/03/about-7-percent- of-kids-worldwide-have-adhd-study

Medscape – March 3 Intralymphatic Injections Safe for Grass Pollen Allergy – Kate Johnson Intralymphatic injections of standard grass-pollen extract are well tolerated and could offer a new and convenient option for treating grass-pollen allergy, new research suggests. "It's interesting," said Hugh Sampson, MD, from Kravis Children's Hospital at Mount Sinai in New York City, who was not involved in the study. "It does seem safe and, if you can do it in three doses, you're definitely going to get better compliance," he told Medscape Medical News. - Dr. Hugh Sampson, Professor, Pediatrics, Allergy and Immunology, Dean, Translational Biomedical Research, Icahn School of Medicine at Mount Sinai Learn more: http://www.medscape.com/viewarticle/840801

Everyday Health – March 3 Running on Empty – Dr. Sanjay Gupta Alanna Finn has type 1 diabetes, which means her body doesn’t make insulin. Insulin is what allows us to get energy from the food we eat, so Finn tests her blood two or three times a day to see how much insulin she needs and gives herself a shot. That’s tricky enough on an ordinary day, so when Finn decided she wanted to train for the New York City Marathon, the first person she talked to was her doctor, David Lam, MD, an endocrinologist at The Mount Sinai Hospital. - Dr. David Lam, Assistant Professor, Medicine, Endocrinology, Diabetes and Bone Disease, Icahn School of Medicine at Mount Sinai Learn more: http://www.everydayhealth.com/news/running-on-empty/

Yahoo News via Good Morning America – March 3 Faith Hill Recovering from Neck Surgery – Abbie Boudreau Citing a source, People magazine has reported that the 47-year-old, five-time Grammy Award winner is recovering from neck surgery. The source told People that Hill, the wife of fellow country music star, Tim McGraw, had surgery in January to correct damage caused by an old injury. Doctors say the procedure Hill underwent is called anterior cervical discectomy and fusion, and they say it’s very common. “We find it in elderly patients very frequently, but it can also occur in younger patients who have experienced some kind of trauma," said Joshua Bederson, MD, chairman of the Department of Neurosurgery for Mount Sinai Health System, who did not treat Hill. "It does occur spontaneously from time to time.” - Dr. Joshua B. Bederson, Professor, Neurology, Icahn School of Medicine at Mount Sinai, Chair, Department of Neurology, Mount Sinai Health System Learn more: https://gma.yahoo.com/faith-hill-recovering-neck-surgery-131459926--abc-news- celebrities.html

Yahoo Parenting – March 3 'Super Powers' Women Have While Pregnant – Jennifer O’Neill Sure, you can’t move around as gracefully while you’re pregnant, and there’s little chance you’ll make it through the entire movie without falling asleep – upright and fully dressed. But there are some amazing things you may discover that body can do when you’re expecting. Having an amazing sense of smell is an example. Pregnant women share this sensory experience often, says Shari Brasner, MD, assistant professor of obstetrics, gynecology and reproductive science at The Mount Sinai Hospital in New York. The sensitivity is reportedly linked to estrogen, which is elevated during pregnancy. “Heightened sense of smell usually relates to a woman’s first trimester nausea, cravings and aversions,” she tells Yahoo Parenting. -Dr. Shari Brasner, Assistant Clinical Professor, Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai Learn more: https://www.yahoo.com/parenting/super-powers-women-have-while-pregnant- 112640176277.html

The Weather Channel – March 3 The Deadly Impact of Winter Weather – Annie Hauser There's been a significant increase in hypothermia deaths in recent years, the U.S. Centers for Disease Control and Prevention said in a new report out Feb. 19, as yet another band of winter weather blankets much of the U.S. "There's a recurrent problem every year, and it always happens during these cold snaps where there are multiple days in a row in which the temperature drops below freezing," Vaishali Patel, MD, an assistant professor of emergency medicine at the Icahn School of Medicine at Mount Sinai, in New York City, told HealthDay News. - Dr. Vaishali Patel, Assistant Professor, Emergency Medicine, Icahn School of Medicine at Mount Sinai Learn more: http://www.weather.com/health/news/hypothermia-deaths-increasing-cdc-says

GoodHousekeeping.com – March 3 6 Embarrassing Skin Problems — And How to Fix Them! – Mona Gohara Almost 8 million Americans suffer from hyperhidrosis — the technical name for over-sweating — and it can definitely mess with your mojo. It can happen in the armpits, hands, feet, and sometimes the face. In most cases, you can thank your DNA. Wearing fabrics that wick moisture from the skin is a good first move, as well as choosing the right deodorant. If over-the-counter stuff hasn't worked, Heidi Waldorf, MD, Director of Laser and Cosmetic Dermatology at The Mount Sinai Hospital in New York, recommends putting on a prescription strength antiperspirant a few times a week. If that doesn't cut it, tiny injections of Botox can stop the problem for six months or more. - Dr. Heidi Waldorf, Associate Clinical Professor, Dermatology, Icahn School of Medicine at Mount Sinai, Director, Laser and Cosmetic Dermatology, The Mount Sinai Hospital Learn more: http://www.goodhousekeeping.com/beauty/anti-aging/embarrassing-skin-problems

WOFL Online – March 3 New Treatment May Offer Prolonged Relief for Migraine Sufferers A common, local anesthetic often used by dentists may offer a new treatment for migraine sufferers. A new study shows that administering lidocaine to a bundle of nerves behind the nose can give chronic migraine sufferers prolonged relief. However, neurologists have expressed skepticism over the technique used in the findings. “That’s not to say that this procedure isn’t good and doesn’t work, but you can’t make any grand claims based on a study that’s open-label and has a mix of patients,” said Lawrence Newman, director of the Mount Sinai-Roosevelt Headache Institute. - Dr. Lawrence Newman, Director of The Headache Institute, Department of Neurology, Mount Sinai Roosevelt Learn more: http://www.myfoxorlando.com/story/28252874/new-treatment-may-offer-prolonged-relief- for-migraine-sufferers

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: [email protected] on behalf of Lindo, Allisa Subject: Mount Sinai In The News - March 3, 2015 Date: Tuesday, March 03, 2015 11:21:29 AM Attachments: ATT00001.txt

In the News March 3, 2015

Crain’s Health Pulse – March 3 Sinai, Bronx-Lebanon Deal The Mount Sinai Health System provided some additional information on its new clinical collaboration with Bronx-Lebanon, announced last week. Arthur Klein, MD, president of the Mount Sinai Health Network, said for now the agreement is a hospital clinical relationship. At some point, it could include Mount Sinai’s medical school, but that is a call to be made by Bronx-Lebanon. Mount Sinai has wanted to have a base in the Bronx from a population-management as well as from a social-responsibility perspective. “Managing that Medicaid population is very important,” said Dr. Klein. - Dr. Arthur Klein, President, The Mount Sinai Health Network Learn more: http://www.crainsnewyork.com/article/20150303/PULSE/150309990/winthrop-university- flexes-financial-strength

Healio – March 3 Presence of Emphysema on CT Scans Increases Lung Cancer Risk Emphysema identified in low-dose CT scans increases the risk for lung cancer regardless of a patient’s smoking history, according to findings from the International Early Lung Cancer Action Program. Claudia I. Henschke, MD, PhD, clinical professor of radiology at The Mount Sinai Hospital, and colleagues evaluated the prevalence of lung cancer based on the presence of emphysema identified by CT scans for both high-risk and low-risk individuals. Researchers stratified findings by participants’ age and smoking history. “Our study demonstrated an increase in the prevalence of lung cancer among those who also had CT evidence of emphysema, thereby demonstrating the importance of identifying emphysema when interpreting a CT scan of the chest,” Henschke and colleagues wrote. - Dr. Claudia Henschke, Clinical Professor, Radiology, Icahn School of Medicine at Mount Sinai Learn more: http://www.healio.com/hematology-oncology/lung-cancer/news/online/%7Be22f0212-e388- 46b7-a4f1-7dc3428c7498%7D/presence-of-emphysema-on-ct-scans-increases-lung-cancer-risk

Medscape – March 2 Peanut Patch to Treat Allergy in the Works – Kate Johnson The daily application of a skin patch (Viaskin, DBV Technologies) that releases peanut protein is effective and safe for peanut immunotherapy, according to the largest clinical trial in peanut allergy desensitization to date. The epicutaneous immunotherapy could be "the first FDA-approved form of therapy for peanut allergy," said Hugh Sampson, MD, from the Jaffe Food Allergy Institute at the Kravis Children's Hospital at Mount Sinai in New York City. Dr. Sampson presented results from the Viaskin Peanut's Efficacy and Safety (VIPES) study here at the American Academy of Allergy, Asthma & Immunology 2015 during a late-breaking abstract session. - Dr. Hugh Sampson, Professor, Pediatrics, Allergy and Immunology, Dean, Translational Biomedical Research, Icahn School of Medicine at Mount Sinai Learn more: http://www.medscape.com/viewarticle/840734 Additional Coverage: Yakima Herald via The Seattle Times: http://www.yakimaherald.com/news/lateststatenews/2961331- 8/peanut-patch-tested-in-seattle-may-be-boon

News AT (Austria) – March 3 This Food is Addictive The phrase: "I am addicted to ..." for example, chocolate is probably familiar to a few of us. But it is actually possible to develop a true-addiction to sweets, snacks and the like? Researchers from the Icahn School of Medicine at Mount Sinai and the University of Michigan interviewed over 500 people and came to the conclusion that it is quite possible to develop an addiction-like behavior in relation to various foods. The consumption of said food causes, as already demonstrated earlier studies, certain changes in the brain that may indicate an addiction, said researcher Nicole Avena, PhD. - Nicole Avena, PhD, Assistant Professor, Pharmacology and Systems Therapeutics, Icahn School of Medicine at Mount Sinai Learn more: http://www.news.at/a/lebensmittel-sucht-studie [Article is in German] Additional Coverage: The Huffington Post Brazil: http://www.brasilpost.com.br/2015/03/02/comidas-viciantes_n_6784798.html [Article is in Portuguese]

Medpage Today – March 2 CardioBreak: Renal Denervation Again, NOAC Reversal Agents – Crystal Phend Hello, snowbirds: Mount Sinai Hospital is following the Cleveland Clinic and Mayo Clinic in expanding into warmer climes. The New York City institution's cardiovascular service is partnering with Jupiter Medical Center in South Florida. But don't confuse it with the Mount Sinai Medical Center Heart Institute already in South Florida, which is affiliated with Columbia University. - The Mount Sinai Hospital Learn more: http://www.medpagetoday.com/Cardiology/Prevention/50268

The New York Times – March 2 Bruised Hip of Nets’ Teletovic Leads to Blood Clot Awareness – Andrew Keh During a game on Jan. 22 at the Los Angeles Clippers, Mirza Teletovic experienced shortness of breath that was worrying enough that he stopped playing and was taken to a hospital. Tests revealed blood clots in the arteries of his lungs, a potentially fatal condition. Alan Benvenisty, MD, a professor of vascular and transplant surgery at the Icahn School of Medicine at Mount Sinai in New York, said the work and travel routines of N.B.A. players could create environments in which the players were at a slightly higher risk. James McKinsey, MD, a surgeon at Mount Sinai Roosevelt, said dehydration, in a minor way, could increase the thickness of a person’s blood, making it more susceptible to clotting. David Forsh, MD, chief of orthopedic trauma at Icahn, guessed that N.B.A. players, given their good physical condition, were at a lower risk for blood clots over all. But he noted that injuries and operations in the lower body were known to put patients at a higher risk for deep vein thrombosis. - Dr. Alan Benvenisty, Professor, Surgery, Icahn School of Medicine at Mount Sinai - Dr. James McKinsey, Attending, Department of Surgery, Mount Sinai Roosevelt - Dr. David Forsh, Assistant Professor, Orthopaedics, Icahn School of Medicine at Mount Sinai Learn more: http://www.nytimes.com/2015/03/03/sports/basketball/bruised-hip-of-nets-teletovic-leads- to-blood-clot-awareness.html?_r=0

ABC News – March 3 Faith Hill Recovering from Neck Surgery Citing a source, People magazine has reported that the 47-year-old, five-time Grammy Award winner is recovering from neck surgery. The source told People that Hill, the wife of fellow country music star, Tim McGraw, had surgery in January to correct damage caused by an old injury. Doctors say the procedure Hill underwent is called anterior cervical discectomy and fusion, and they say it’s very common. “We find it in elderly patients very frequently, but it can also occur in younger patients who have experienced some kind of trauma," said Joshua Bederson, MD, chairman of the Department of Neurosurgery for Mount Sinai Health System, who did not treat Hill. "It does occur spontaneously from time to time.” - Dr. Joshua B. Bederson, Professor, Neurology, Icahn School of Medicine at Mount Sinai, Chair, Department of Neurology, Mount Sinai Health System Learn more: http://abcnews.go.com/Entertainment/faith-hill-recovering-neck-surgery/story?id=29343588

Healio – February 2015 Therapeutic Drug Monitoring in IBD According to experts interviewed by Healio Gastroenterology, therapeutic drug monitoring of biologics is far more complex than with thiopurines, largely due to issues stemming from the development of antidrug antibodies that interfere with biologic activity. A recent study by Marla C. Dubinsky, MD, MS, chief of pediatric gastroenterology and hepatology, and co-director of the Feinstein Inflammatory Bowel Disease Clinical Center at Icahn School of Medicine at Mount Sinai, even identified a dose threshold of methotrexate that decreased drug clearance by reducing the production of antidrug antibodies. The evidence for how to best utilize drug monitoring in practice, however, is somewhat limited, and varies depending on many factors, including whether a patient has primary nonresponse or secondary loss of response, according to Bruce E. Sands, MD, MS, also from the Icahn School of Medicine at Mount Sinai. -Dr. Marla C. Dubinsky, Senior Faculty, Medicine, Pediatrics, Gastroenterology, Co-Director, Feinstein Inflammatory Bowel Disease Clinical Center, Icahn School of Medicine at Mount Sinai, Chief, Pediatric Gastroenterology, Hepatology, Kravis Children’s Hospital at Mount Sinai - Dr. Bruce Sands, Professor, Medicine, Gastroenterology, Dr. Burrill B. Crohn Professor of Medicine, Icahn School of Medicine at Mount Sinai Learn more: http://www.healio.com/gastroenterology/inflammatory-bowel-disease/news/print/healio- gastroenterology/%7B6eb50c6a-5504-4541-a420-3ffa003f5b40%7D/therapeutic-drug-monitoring-in-ibd

U.S. News & World Report – March 2 Hair Loss: Not Just a Man's Issue – Anna Medaris Miller In addition to autoimmune conditions like alopecia areata and run-of-the-mill hair loss related to genetics, female hair loss can be triggered by childbirth, extreme stress, fad diets and going on and off hormonal birth control. Sometimes, these and other lifestyle changes prompt more hair follicles than normal to go into a resting state, in which the loss is called telogen effluvium – a temporary and reversible condition. Other times, hair loss is a sign of a nutritional deficiency or reaction to hair products. It can also be a symptom of rheumatic conditions like lupus, androgen disorders like polycystic ovaryian syndrome or endocrine conditions like thyroid disease, says Rhoda Cobin, a clinical professor in the endocrinology division at The Mount Sinai Hospital. - Dr. Rhoda Cobin, Clinical Professor, Medicine, Endocrinology, Diabetes and Bone Disease, Icahn School of Medicine at Mount Sinai Learn more: http://health.usnews.com/health-news/patient-advice/articles/2015/03/02/hair-loss-not-just- a-mans-issue

Healthday – March 2 Growth Checks in Children Might Spot Celiac Disease – Robert Preidt Checking children for growth problems may help identify those with celiac disease, according to a new study. Celiac disease is an autoimmune disorder in which the body has an immune reaction to a component of wheat called gluten, leading to damage to the small intestine. According to the Celiac Disease Foundation, the illness strikes about one in every 100 people worldwide. Celiac disease is typically difficult to diagnose. It leads to "short stature, poor weight gain and poor growth, and has been underdiagnosed in children," said one expert, Gina Sam, MD, director of the Gastrointestinal Motility Center at Mount Sinai in New York City. - Dr. Gina Sam, Assistant Professor, Medicine, Gastroenterology, Icahn School of Medicine at Mount Sinai, Director, Mount Sinai Gastrointestinal Motility Center at The Mount Sinai Hospital Learn more: http://consumer.healthday.com/gastrointestinal-information-15/gastrointestinal-problems- news-330/growth-checks-might-spot-celiac-disease-in-children-696936.html

Harper’s Magazine – April 2014 Diagnose This – Heidi Julavits The most promising sign of medical-education reform is the Icahn School of Medicine at Mount Sinai’s “early assurance” program. Begun in 1987, this program allows interested students to apply and be accepted after their freshman year of college. The official name of Mount Sinai’s early-assurance program is HuMed. - Icahn School of Medicine at Mount Sinai Learn more: http://harpers.org/archive/2014/04/diagnose-this/ [Login Required]

The Huffington Post – March 2 9 Foods That Keep You Feeling Full Longer – Linda Melone When you’re hungry you’ll grab the quickest food within reach and forget all your good intentions. It’s one reason why only one out of five people can last a month before falling off the diet wagon, according to a British survey. The foods you choose, however, can make all the difference between feeling hungry again within a half hour and being satisfied for several hours. “Key components of highly satisfying foods are protein and fiber,” says Rebecca Solomon, director of clinical nutrition at Mount Sinai Beth Israel, in New York City. “My rule is fiber plus protein equals full.” - Rebecca Solomon, MS, RD, CDN, Director, Clinical Nutrition, Mount Sinai Beth Israel Learn more: http://www.huffingtonpost.com/2015/03/03/filling-foods-_n_6762912.html

Yahoo Beauty via Allure – March 2 How to Get—and Keep—Perfect Skin – Elizabeth Siegel If you haven’t heard of essences, they’re an Asian skin-care import that are as light as toners—but instead of cleansing or stripping the skin with alcohol, they hydrate with a humectant, like glycerin. And if adding an extra product to your skin-care routine sounds like a pain, we’ve got two good reasons to reconsider: First, essences make skin really dewy right away; second, they make the rest of your skin- care routine more effective. “Essences soften dead skin cells on the stratum corneum, so anything you put on top penetrates the skin more effectively,” says Joshua Zeichner, MD, the director of cosmetic and clinical research at The Mount Sinai Hospital in New York City. - Dr. Joshua Zeichner, Assistant Professor, Dermatology, Icahn School of Medicine at Mount Sinai Learn more: https://www.yahoo.com/beauty/how-to-get-and-keep-perfect-skin-in-2015- 109603932646.html

Shape – March 2 Is an IUD the Best Birth Control Option for You? – Jenna Birch Have you noticed all the buzz surrounding the IUD lately? Intrauterine devices (IUDs) have seemingly been everywhere. Here's what you need to know about the contraceptive. There are two versions of the IUD to note: the five-year hormonal and the 10-year non-hormonal. The hormonal works by releasing progestin, which thickens cervical mucus and basically makes the womb inhospitable for an egg, says Taraneh Shirazian, MD, assistant professor of obstetrics, gynecology and reproductive science at The Mount Sinai Hospital. - Dr. Taraneh Shirazian, Assistant Professor, Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai Learn more: http://www.shape.com/lifestyle/sex-and-love/iud-best-birth-control-option-you

Cosmopolitan – March 3 10 Things You Never Knew about Your Vagina – Lane Moore The way I see it, there's no way anyone can know everything about their vagina. There have to be some rarely known facts about them that only doctors or scientists know. So when I went looking for these facts, most of them seemed like there was no way they could be true, or they seemed like they could be true, but I didn't know why. I spoke with Laurence Orbuch, MD, Director of GYN Laparoscopic Associates and the co-director of Gynecologic Robotic Surgery at Mount Sinai Beth Israel in New York City, about the hows and the whys of these bizarre (but really cool) vagina facts. - Dr. Laurence Orbuch, Assistant Clinical Professor, Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai, Co-Director, Gynecologic Robotic Surgery, Mount Sinai Beth Israel Learn more: http://www.cosmopolitan.com/sex-love/news/a37126/things-you-never-knew-about-your- vagina/

WCBS TV – March 3 Experts: Earbuds Could Be Putting Kids at Increased Risk for Hearing Loss A new study shows half of all 12- to 35-year-olds listen to their music too loud. As Ana Kim, MD, Associate Professor of Otolaryngology, New York Eye and Ear Infirmary of Mount Sinai, explained to WCBS TV, listening to music with earbuds on a device at the highest volume can ruin a child’s hearing forever in just 15 minutes. “A general rule I tell them is 50 percent of the volume, so middle level,” Dr. Kim said. - Dr. Ana Kim, Associate Professor, Otolaryngology, Otology, Neurology, Director, Otologic Research, New York Eye and Ear Infirmary of Mount Sinai Learn more: http://newyork.cbslocal.com/2015/03/02/experts-earbuds-could-be-putting-kids-at- increased-risk-for-hearing-loss/

Closer – March 2 Look Your Most Beautiful Q: How can I get the smoothest shave? A: “The best time to shave is after a hot shower or bath,” says NYC-based dermatologist Gary Goldenberg, MD. “Heat opens up the hair follicles, allowing for a closer shave.” The products you use make a difference too. “Make sure you use a moisturizing shaving cream and a sharp razor. Dull razors drag the hair before cutting it, causing bumps and infection.” Apply a cool towel onto skin when done, which closes the hair follicles and leaves skin silky. - Dr. Gary Goldenberg, Assistant Professor, Dermatology, Pathology, Icahn School of Medicine at Mount Sinai Learn more: No Web Link Available

Yale Daily News – March 3 Study Uncovers Science Behind “The Munchies” – Steven Lewis A study led by Yale researchers has uncovered a novel contribution of a subset of neurons in driving marijuana induced feeding, otherwise known as “the munchies.” Professor of psychiatry, neuroscience and pharmacology at Mount Sinai Hospital Yasmin Hurd, who was not involved in the study, praised its simplicity and apt use of model organisms. “I thought it was a beautiful, mechanistic study. You cannot achieve this kind of mechanistic understanding in humans, so I do think these animal models were quite appropriate for the questions they were asking,” she said, adding that studies of this quality are rare in the field of marijuana research. - Dr. Yasmin Hurd, Professor, Psychiatry, Neuroscience, Pharmacology and Systems Therapeutics, Icahn School of Medicine at Mount Sinai Learn more: http://yaledailynews.com/blog/2015/03/03/why-the-munchies-science/

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: [email protected] on behalf of Lindo, Allisa Subject: Mount Sinai In The News - March 2, 2015 Date: Monday, March 02, 2015 12:17:01 PM Attachments: ATT00001.txt

In the News March 2, 2015

Medical Xpress – February 27 Researchers Find Chemotherapy after Bladder Cancer Surgery Improved Survival Patients that received chemotherapy after bladder cancer surgery demonstrated an approximately 30% lower risk of death than those that underwent surgery alone, according to an analysis to be presented by researchers at the Icahn School of Medicine at Mount Sinai at the 2015 Genitourinary Cancers Symposium. Lead researcher Matthew Galsky, MD and colleagues used a large database of patients diagnosed with cancer in the United States. Specifically, the study found that patients receiving adjuvant chemotherapy after surgical treatment had improved overall survival when compared to patients that received surgical treatment alone with only post-surgical observation. "Until now, data supporting adjuvant chemotherapy has been mixed," said lead Dr. Galsky, Associate Professor of Medicine, Hematology and Medical Oncology, and Assistant Professor, Urology at the Icahn School of Medicine at Mount Sinai. - Dr. Matthew Galsky, Associate Professor, Medicine, Hematology and Medical Oncology, Assistant Professor, Urology, Icahn School of Medicine at Mount Sinai Learn more: http://medicalxpress.com/news/2015-02-chemotherapy-bladder-cancer-surgery-survival.html Additional Coverage: Urologic Cancer Advisor: http://www.cancertherapyadvisor.com/advanced-bladder-cancer-adjuvant-chemotherapy-better-survival-treatment/article/400793/

HuffPost Live – February 26 Top Stories for Wednesday, February 25 - Caroline Modarressy-Tehrani We all say that we are addicted to donuts or candy. There’s actually scientific evidence that proves this might be true. Highly processed, fatty, sugary foods can cause addicting patterns and are becoming more problematic in people’s lives. “According to the study that we conducted, we found that it was the foods that were most identified as being particularly problematic and associated with addictive like eating were things such as pizza, chocolate, chips, cookies and ice cream. Those were really the top 5,” says Nicole Avena, PhD, a researcher from the Icahn School of Medicine at Mount Sinai. - Nicole Avena, PhD, Assistant Professor, Pharmacology and Systems Therapeutics, Icahn School of Medicine at Mount Sinai Learn more: http://live.huffingtonpost.com/r/segment/obama-chris-christie-american-sniper-top-stories-for-wednesday/54eb895902a760b7090006c3

Science Codex– February 28 New Compounds Protect Nervous System from Structural Damage of MS A newly characterized group of pharmacological compounds block both the inflammation and nerve cell damage seen in mouse models of multiple sclerosis, according to a study conducted at the Icahn School of Medicine at Mount Sinai. "The compounds identified in this study, when administered orally, both reduced the inflammation that is a hallmark of multiple sclerosis and protected against the nerve cell damage seen in mouse models of the disease," said Jeffery Haines, PhD, a post-doctoral fellow at Mount Sinai and the study's lead author. "The study results elucidate the molecular mechanisms underlying disease progression in multiple sclerosis models, providing a basis for future clinical trials to determine safety and efficacy of these chemical agents in humans with demyelinating disorders," says Patrizia Casaccia, MD, PhD, Professor of Neuroscience, Genetics and Genomic Sciences at Mount Sinai and senior author of the study. - Dr. Patrizia Casaccia, Professor, Neuroscience, Genetics and Genomic Science, Neurology, Icahn School of Medicine at Mount Sinai, Chief, the Center of Excellen for Myelin Repair, the Friedman Brain Institute at Mount Sinai - Jeffrey Haines, PhD, Postdoctoral Fellow, Neuroscience, Icahn School of Medicine at Mount Sinai Learn more: http://www.sciencecodex.com/new_compounds_protect_nervous_system_from_the_structural_damage_of_ms-151813 Additional Coverage: Medical Xpress: http://medicalxpress.com/news/2015-02-compounds-nervous-ms.html

South Florida Business Journal – February 27 Jupiter Medical Center partners with major New York hospital – Brian Bandell Jupiter Medical Center signed a patient care partnership agreement with the Mount Sinai Hospital in New York. The New York hospital is ranked among the top 10 in the nation for cardiology and heart surgery by U.S. News & World Report so the affiliation will extend considerable expertise and marketing clout to the Jupiter non-profit hospital. They will partner on cardiac services and research. "Our new partnership with Jupiter Medical Center represents an integral step in providing access and continuity of care for our patients that share a common link and split their time between New York and South Florida," said Arthur A. Klein, MD, president of the Mount Sinai Health Network. - Dr. Arthur Klein, President, The Mount Sinai Health Network Learn more: http://www.bizjournals.com/southflorida/news/2015/02/27/jupiter-medical-center-partners-with-major-new.html

CBS 60 Minutes – March 1 Lumber Liquidators Linked to Health and Safety Violations – Anderson Cooper 60 Minutes found that Lumber Liquidators' Chinese-made laminate flooring contains amounts of toxic formaldehyde that may not meet health and safety standards. Anderson Cooper reports on the discovery. “It’s not a safe level. It’s a level that the US EPA calls polluted indoor conditions,” says Philip Landrigan, MD, of New York’s The Mount Sinai Hospital, who specializes in environmental pediatrics and exposure to toxic chemicals. - Dr. Philip Landrigan, Professor and System Chair, Preventative Medicine, Professor, Pediatrics, Dean for Global Health, Icahn School of Medicine at Mount Sinai Learn more: http://www.cbsnews.com/videos/lumber-liquidators-linked-to-health-and-safety-violations/ Additional Coverage: New York Daily News: http://www.nydailynews.com/news/national/lumber-liquidators-laminate-formaldehyde-suit-article-1.2134097

Healio – February 27 FDA Advisory Committee Recommends Radiesse For Hand Augmentation The General and Plastic Surgery Devices Panel of the FDA’s Medical Devices Advisory Committee has voted in favor of recommending expanding the indication of Merz’s Radiesse Dermal Filler to include hand augmentation for volume correction. “Hands have been a real unmet need [in cosmetic surgery],” according to Heidi A. Waldorf, MD, a clinical professor of dermatology at Mount Sinai Hospital. Waldorf went on to say that addressing patients’ aging hands goes beyond a “luxury item,” since often the first interaction people have is a handshake, making the hands the first thing people see upon meeting someone new. - Dr. Heidi Waldorf, Associate Clinical Professor, Dermatology, Icahn School of Medicine at Mount Sinai, Director, Laser and Cosmetic Dermatology, The Mount Sinai Hospital Learn more: http://www.healio.com/aesthetics/injectables-and-fillers/news/online/%7Bc02d70d7-58a5-442f-b10e-9b47cc94f9cb%7D/fda-advisory-committee-recommends-radiesse-for-hand- augmentation

World Science Festival – February 17 Chatting with ‘Still Alice’ Advisor Mary Sano Julianne Moore is up for an Oscar. Mary Sano leads the Alzheimer’s disease research at The Icahn School of Medicine at Mount Sinai. The two women might never have crossed paths. But for her turn as Dr. Alice Howland in the movie Still Alice, Moore did some research into the disease. That legwork led her to Sano, who gave Moore pointers on how to accurately portray a linguistics professor whose world is fundamentally shaken by the effects of early-onset Alzheimer’s disease. -Mary Sano, PhD, Professor, Psychiatry, Associate Dean for Clinical Research, Director of Alzheimer’s Disease Research, Icahn School of Medicine at Mount Sinai Learn more: http://www.worldsciencefestival.com/2015/02/cinema-peer-review-still-alice/?utm_source=World+Science+Festival+Newsletter+Subscribers&utm_campaign=155a8c5456- Content_Newsletter_20150220&utm_medium=email&utm_term=0_0bda9af79e-155a8c5456-30587501

Healio – February 23 Vitamin D Deficits More Closely Related to Diabetes than to Obesity – Gerald Bernstein, MD Vitamin D is different from other vitamins. It appears in the body from what we consume, but it is also produced in the skin in response to sunlight. Although vitamin D is historically known for its association with calcium metabolism, observations made in the last couple decades suggest additional functions. It is a vitamin that also appears to act like a hormone. Researchers in the United States and elsewhere are currently conducting studies that aim to firm up such associations. To date there is no recognized functional relation between vitamin D and type 2 diabetes. However, there are many questions to be answered. -Dr. Gerald Bernstein, Associate Clinical Professor, Medicine, Endocrinology, Diabetes and Bone Disease, Icahn School of Medicine at Mount Sinai Learn more: http://www.healio.com/endocrinology/diabetes/news/online/%7B54f87e4f-c6f0-4b58-a061-a4cf72a1d196%7D/vitamin-d-deficits-more-closely-related-to-diabetes-than-to-obesity

Forbes – February 27 Three Things You Should Know before Your Endoscopy – Jonathan E. Aviv, MD The recent news story about patients at UCLA medical center developing a life-threatening infection has been shocking. Two of seven infected patients died from the nightmare bacteria carbapenem-resistant Enterobacteriaceae (CRE) after an ordinary medical device was used to inspect their digestive system. In this specific case, a type of endoscope called a duodenoscope was used to perform the procedure. Although the design of the duodenoscope largely carried the blame, the medical community should now be looking to make all types of upper endoscopy safer, because many of them have been implicated in other outbreaks of dangerous bacteria and viruses. - Dr. Jonathan Aviv, Clinical Professor, Otolaryngology, Icahn School of Medicine at Mount Sinai Learn more: http://www.forbes.com/sites/stephenbrozak/2015/02/27/3-things-you-should-know-before-your-endoscopy/

USA Today – February 28 The Science Behind 'The Dress'– Lori Grisham The debate over whether "the dress" is blue/black or white/gold continues, but there's real science behind why we see it differently. USA TODAY Network asked experts to explain what's going on with the dress that mesmerized the Internet. Reena Garg, MD, an ophthalmology professor, says you also have to understand the science of how people view color — and how that, in turn, can be affected by the lighting of a photograph. Cells in our eyes are light sensitive and help us tell the difference between color and shade, Garg, of the New York Eye and Ear Infirmary of Mount Sinai, said in an e-mail. Those cells are called rods and cones, she says. - Dr. Reena Garg, Assistant Professor, the New York Eye and Ear Infirmary of Mount Sinai Learn more: http://www.usatoday.com/story/news/nation-now/2015/02/27/dress-blue-black-white-gold-science/24113695/ Additional Coverage: CBS This Morning: http://www.cbsnews.com/news/blue-black-white-gold-dress-color-debate-goes-viral/ WABC: http://7online.com/fashion/what-color-is-this-dress-join-the-debate/536460/ The New York Daily News: http://www.nydailynews.com/life-style/experts-dress-blue-black-white-gold-article-1.2131551 Yahoo Health: https://www.yahoo.com/health/what-thedress-color-you-see-says-about-you-112243093272.html

Common Health – February 27 What New Peanut Study Means For Kids with Food Allergies — And What It Doesn’t – Richard Knox A new study means that the recommendations parents have been given over the past 15 years — to withhold peanuts until the age of 3 in children deemed at risk —are wrong. In 2008, the American Academy of Pediatrics withdrew its recommendation to withhold peanuts until age 3, but until now there’s been no solid evidence in favor of deliberately feeding peanuts to at-risk kids. That’s what the new study strongly suggests parents should do — strictly under the supervision of their pediatricians. Hugh Sampson, MD, director of the Food Allergy Institute at the Icahn School of Medicine at Mount Sinai in New York, says the research is a landmark because “I can finally look a mother in the eye and give her some advice that I feel confident in. This is a definite cause-and-effect phenomenon.” - Dr. Hugh Sampson, Professor, Pediatrics, Allergy and Immunology, Dean, Translational Biomedical Research, Icahn School of Medicine at Mount Sinai Learn more: http://commonhealth.wbur.org/2015/02/new-peanut-allergy-study-means Additional Coverage: Ames Tribune via the Seattle Times: http://amestrib.com/news/how-skin-patch-could-be-safe-treatment-peanut-allergies

Palm Beach Post – March 2 Jupiter Medical Center: Prevent Heart Disease with Mediterranean Diet The core idea of the Mediterranean Diet is that it is not a quick fix to lose those last pesky five pounds but a lifestyle choice that could lead to better health, and in particular, a healthier heart. Jupiter Medical Center has recently partnered with Mount Sinai Hospital, New York to form Mount Sinai Heart New York at Jupiter Medical Center in an effort to transform cardiac care in our community. This partnership will allow the two hospitals to share research, techniques, and best practices, all for the benefit of patients. Gonzalo Loveday, MD, Medical Director of Mount Sinai Heart New York at Jupiter Medical Center, advocates for this type of approach to diet in order to maintain a healthy heart and to keep heart disease at bay. - Dr. Gonzalo Loveday, Medical Director, Mount Sinai Heart New York at Jupiter Medical Center Learn more: http://www.palmbeachpost.com/news/lifestyles/health/jupiter-medical-center-prevent-heart-disease-with-/nkD8h/

Business Insider via Agence France-Presse – February 27 Black/Blue Or White/Gold? Dress Debate Goes Viral – Richard Knox Is the dress black and blue, or white and gold? That question is lighting up the Internet. Reena Garg, MD, an assistant professor at the New York Eye and Ear Infirmary of Mount Sinai in New York, said the varied reactions can be explained by how we understand color, noting that the poorly exposed photograph was likely taken with a cell phone camera. "If you see the dress as black and blue, you're probably seeing the photo as over-exposed, meaning there is too much light, so the colors in the dress appear darker to you after the retina has compensated," Garg told AFP. - Dr. Reena Garg, Assistant Professor, the New York Eye and Ear Infirmary of Mount Sinai Learn more: http://www.businessinsider.com/afp-black/blue-or-white/gold-dress-debate-goes-viral-2015-2 Additional Coverage: NBC Nightly News: http://www.nbcnews.com/nightly-news/science-behind-black-blue-or-white-gold-dress-n314476 WCBS TV: http://newyork.cbslocal.com/video/11183955-white-and-gold-or-blue-and-black-social-media-explodes-over-dress/ I24 News: http://www.i24news.tv/en/news/culture/62598-150227-black-blue-or-white-gold-dress-debate-goes-viral Elle: http://www.elle.com/culture/celebrities/news/a27026/what-color-is-the-dress-reactions/ Medical Xpress: http://medicalxpress.com/news/2015-02-blackblue-whitegold-debate-viral.html

Medpage Today – February 27 Cohen's Brain Bits: Looks like Teen Spirit – Joshua Cohen, MD, MPH I have always loved working with adolescents and have made it central to my career as an adolescent headache specialist. With each of my adolescent patients, I dedicate time to speak with them, without parents present, about the sensitive subjects that often dominate their thoughts. Neurologists have long puzzled over the role of different brain regions and their connections in predicting behavior. For experimental, impulsive, and potentially perilous actions, one prime candidate for localization has been the rostrolateral prefrontal cortex (RPC). - Dr. Joshua Cohen, Assistant Professor, Neurology, Icahn School of Medicine at Mount Sinai Learn more: http://www.medpagetoday.com/Blogs/CohensBrainBits/50224?xid=nl_mpt_DHE_2015-02- 28&utm_content=&utm_medium=email&utm_campaign=DailyHeadlines&utm_source=ST&eun=g834835d0r&userid=834835&email=newsmedia%40mssm.edu&mu_id=6915236&utm_term=Daily

FoxNews.com – March 1 Migraine Treatment Using X-Ray Guidance May Hold Potential for Relief – Melinda Carstensen Preventive treatment for migraines has eluded doctors for decades. Now, a team of radiologists are reporting preliminary findings that may indicate promise for a common technique to mitigate severe headaches. However, neurologists have expressed skepticism over the technique used in the findings. “That’s not to say that this procedure isn’t good and doesn’t work, but you can’t make any grand claims based on a study that’s open-label and has a mix of patients,” said Lawrence Newman, director of the Mount Sinai-Roosevelt Headache Institute. - Dr. Lawrence Newman, Director of The Headache Institute, Department of Neurology, Mount Sinai Roosevelt Learn more: http://www.foxnews.com/health/2015/03/01/migraine-treatment-using-x-ray-guidance-may-hold-potential-for-relief/

Fitness – February 27 6 Things You Need to Know About Retinol – Chelsea Burns You've heard retinol is great at fighting wrinkles, but did you know it could also prevent acne and shrink pores? We asked Joshua Zeichner, MD, dermatologist and director of cosmetic research at The Mount Sinai Hospital in New York City, to tell us everything we need to know about the power player ingredient. - Dr. Joshua Zeichner, Assistant Professor, Dermatology, Icahn School of Medicine at Mount Sinai Learn more: http://www.fitnessmagazine.com/beauty/skin-care/retinol/

The Huffington Post via Health.com – February 28 How to Beat a Bad Mood – Jancee Dunn Refined sugar is a crabbiness culprit. That vending-machine candy bar will spike your blood sugar—then plunge both it and your mood lower. Down too much sugar and the brain's reward system goes through withdrawal if you don't give it a constant supply, says Nicole Avena, PhD, assistant professor at the Icahn School of Medicine at Mount Sinai in New York City. "The resulting 'sugar rage' looks like what you'd see if there was an addiction to something like nicotine," she says. "There have been lab studies on rats that eat sugar where the rats will actually bite investigators when they take it away because they're so angry." - Nicole Avena, PhD, Assistant Professor, Pharmacology and Systems Therapeutics, Icahn School of Medicine at Mount Sinai Learn more: http://www.huffingtonpost.com/2015/02/28/beat-bad-mood_n_6753266.html Additional Coverage: The Beacon Review: http://www.thebeaconreview.com/entertainment/how-to-defeat-a-undesirable-temper-h4665.html

Reno Gazette-Journal – February 27 Diet Detective: Cold Weather Tips – Charles Platkin Alexis Chiang Colvin, MD, an associate professor of sports medicine in the department of orthopedic surgery at Icahn School of Medicine at Mount Sinai in New York, has a few tips for a healthy skiing, snowboarding or ice skating experience. First she says take a lesson. For beginners, it is important to learn how to stop safely; for the advanced, a lesson by a professional can help correct bad or unsafe habits. -Dr. Alexis Colvin, Associate Professor, Orthopaedics, Icahn School of Medicine at Mount Sinai Learn more: http://www.rgj.com/story/life/food/2015/02/27/diet-detective-cold-weather-tips/24153369/

New York Daily News – March 1 The Cold-Weather Malady Known as Reynaud's Phenomenon Can Be Both Prevented and Managed – Katie Charles This eternal winter may have you wondering if you have a particular susceptibility to the cold. “Raynaud’s Phenomenon, or RP, is an exaggerated response to cold, and it’s a very common thing — as many as 20% of women and 14% of men may be affected,” says Samuel Altstein, MD, an attending in the department of family medicine at Mount Sinai Beth Israel. “Patients with Raynaud’s Phenomenon have cold hands and feet because, in response to cold temperatures, the blood vessels in their fingers and toes constricts more than average.” -Dr. Sam Altstein, Medical Director, Mount Sinai Beth Israel Medical Group Learn more: http://www.nydailynews.com/life-style/health/reynaud-phenomenon-exaggerated-response-cold-article-1.2126337

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