GOLGA3 Antibody

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Product Datasheet GOLGA3 antibody Catalog No: #22143 Orders: [email protected] Description Support: [email protected] Product Name GOLGA3 antibody Host Species Rabbit Clonality Polyclonal Purification Purified by antigen-affinity chromatography. Applications WB IHC IF Species Reactivity Hu Immunogen Type Peptide Immunogen Description Synthetic peptide contain a sequence corresponding to a region within amino acids 1436 and 1498 of Golgi autoantigen, golgin subfamily a, 3 Target Name GOLGA3 Accession No. Swiss-Prot:Q08378Gene ID:2802 Concentration 1mg/ml Formulation Supplied in 1XPBS, 1%BSA, 20% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative. Storage Store at -20°C for long term preservation (recommended). Store at 4°C for short term use. Application Details Predicted MW: 167kd Western blotting: 1:500-1:3000 Immunohistochemistry: 1:100-1:250 Immunofluorescence: 1:100-1:200 Images Sample(30 ug of whole cell lysate) A: A431 B: H1299 5% SDS PAGE Primary antibody diluted at 1: 1000 Address: 8400 Baltimore Ave., Suite 302, College Park, MD 20740, USA http://www.sabbiotech.com 1 Immunohistochemical analysis of paraffin-embedded gastric tissue, using GOLGA3 antibody at 1: 100 dilution. Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using GOLGA3 antibody at 1: 200 dilution. Background The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs). Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. This gene encodes a member of the golgin family of proteins which are localized to the Golgi. Its encoded protein has been postulated to play a role in nuclear transport and Golgi apparatus localization. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of these variants has not been determined. [provided by RefSeq] Note: This product is for in vitro research use only and is not intended for use in humans or animals. Address: 8400 Baltimore Ave., Suite 302, College Park, MD 20740, USA http://www.sabbiotech.com 2.

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Application to Neuroimaging Biomarkers in Alzheimer's
The Author(s) BMC Medical Informatics and Decision Making 2017, 17(Suppl 1):61 DOI 10.1186/s12911-017-0454-0 RESEARCH Open Access Knowledge-driven binning approach for rare variant association analysis: application to neuroimaging biomarkers in Alzheimer’s disease Dokyoon Kim1,2, Anna O. Basile2, Lisa Bang1, Emrin Horgusluoglu4, Seunggeun Lee3, Marylyn D. Ritchie1,2, Andrew J. Saykin4 and Kwangsik Nho4* From The 6th Translational Bioinformatics Conference Je Ju Island, Korea. 15-17 October 2016 Abstract Background: Rapid advancement of next generation sequencing technologies such as whole genome sequencing (WGS) has facilitated the search for genetic factors that influence disease risk in the field of human genetics. To identify rare variants associated with human diseases or traits, an efficient genome-wide binning approach is needed. In this study we developed a novel biological knowledge-based binning approach for rare-variant association analysis and then applied the approach to structural neuroimaging endophenotypes related to late-onset Alzheimer’sdisease(LOAD). Methods: For rare-variant analysis, we used the knowledge-driven binning approach implemented in Bin-KAT, an automated tool, that provides 1) binning/collapsing methods for multi-level variant aggregation with a flexible, biologically informed binning strategy and 2) an option of performing unified collapsing and statistical rare variant analyses in one tool. A total of 750 non-Hispanic Caucasian participants from the Alzheimer’s Disease Neuroimaging Initiative (ADNI) cohort who had both WGS data and magnetic resonance imaging (MRI) scans were used in this study. Mean bilateral cortical thickness of the entorhinal cortex extracted from MRI scans was used as an AD-related neuroimaging endophenotype.
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Tepzz 8Z6z54a T
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Downloaded from the Biogrid Database [30] Contain- the Immune System [12–15]
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146823088.Pdf
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