bioRxiv preprint doi: https://doi.org/10.1101/2020.12.01.391268; this version posted January 1, 2021. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under aCC-BY 4.0 International license. Neuroprotective mechanisms of red clover and soy isoflavones in Parkinson’s disease models Aurélie de Rus Jacquet1,2*, Abeje Ambaw3,4, Mitali Arun Tambe1,5, Sin Ying Ma1, Michael Timmers6,7, Qing-Li Wu8, James E. Simon8, George P. McCabe9, Mary Ann Lila6, Riyi Shi3,10,11, Jean-Christophe Rochet1,11*. 1Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN, 47907, USA 2Present affiliations: Centre de Recherche du CHU de Québec, Axe Neurosciences, Québec, QC, G1V 4G2, Canada, and Département de Psychiatrie & Neurosciences, Université Laval, Québec, QC, G1V 0A6, Canada 3Department of Basic Medical Sciences, Purdue University, West Lafayette, IN, 47907, USA 4Present affiliation: Physiology Department, Monterey Peninsula College, Monterey, CA, 93940, USA. 5Present affiliation: National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, MD, USA 6Plants for Human Health Institute, Department of Food Bioprocessing and Nutrition Sciences, North Carolina State University, Kannapolis, NC, 28081, USA 7Present affiliation: Berry Blue, Kannapolis, NC, 28081, USA 8Department of Plant Biology, Rutgers University, New Brunswick, NJ, 08901, USA 9Department of Statistics, Purdue University, West Lafayette, IN 47907, USA 10Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN, 47907, USA 11Purdue Institute for Integrative Neuroscience, Purdue University, West Lafayette, IN, 47907, USA * Corresponding authors: Jean-Christophe Rochet:
[email protected] Aurélie de Rus Jacquet:
[email protected] 1 bioRxiv preprint doi: https://doi.org/10.1101/2020.12.01.391268; this version posted January 1, 2021.