FKBP3 Antibody Cat

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FKBP3 Antibody Cat. No.: 22-545 FKBP3 Antibody Immunoprecipitation analysis of 200ug extracts of MCF-7 cells, using 3 ug FKBP3 antibody (22-545). Immunofluorescence analysis of HeLa cells using FKBP3 antibody (22-545). Blue: Western blot was performed from DAPI for nuclear staining. the immunoprecipitate using FKBP3 antibody (22-545) at a dilition of 1:1000. Specifications HOST SPECIES: Rabbit SPECIES REACTIVITY: Human Recombinant fusion protein containing a sequence corresponding to amino acids 1-224 of IMMUNOGEN: human FKBP3 (NP_002004.1). TESTED APPLICATIONS: IF, IP, WB September 29, 2021 1 https://www.prosci-inc.com/fkbp3-antibody-22-545.html WB: ,1:500 - 1:2000 APPLICATIONS: IF: ,1:50 - 1:100 IP: ,1:50 - 1:100 POSITIVE CONTROL: 1) HeLa 2) MCF-7 3) BT-474 PREDICTED MOLECULAR Observed: 30kDa WEIGHT: Properties PURIFICATION: Affinity purification CLONALITY: Polyclonal ISOTYPE: IgG CONJUGATE: Unconjugated PHYSICAL STATE: Liquid BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. STORAGE CONDITIONS: Store at -20˚C. Avoid freeze / thaw cycles. Additional Info OFFICIAL SYMBOL: FKBP3 FKBP3, 25 kDa FK506-binding protein, 25 kDa FKBP, FKBP-3, Immunophilin FKBP25, FK506- ALTERNATE NAMES: binding protein 3, FK506-binding protein 3 (25kD), PPIase FKBP3, Rapamycin binding protein, Rotamase, PPIase, FK506 binding protein 3, 25kDa, FKBP-25, FKBP25 GENE ID: 2287 USER NOTE: Optimal dilutions for each application to be determined by the researcher. Background and References The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the BACKGROUND: immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin. September 29, 2021 2 https://www.prosci-inc.com/fkbp3-antibody-22-545.html ANTIBODIES FOR RESEARCH USE ONLY. For additional information, visit ProSci's Terms & Conditions Page. September 29, 2021 3 https://www.prosci-inc.com/fkbp3-antibody-22-545.html.

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