FKBP3 Antibody Cat. No.: 22-545

FKBP3 Antibody

Immunoprecipitation analysis of 200ug extracts of MCF-7 cells, using 3 ug FKBP3 antibody (22-545). Immunofluorescence analysis of HeLa cells using FKBP3 antibody (22-545). Blue: Western blot was performed from DAPI for nuclear staining. the immunoprecipitate using FKBP3 antibody (22-545) at a dilition of 1:1000.

Specifications

HOST SPECIES: Rabbit

SPECIES REACTIVITY: Human

Recombinant fusion protein containing a sequence corresponding to amino acids 1-224 of IMMUNOGEN: human FKBP3 (NP_002004.1).

TESTED APPLICATIONS: IF, IP, WB

September 29, 2021 1 https://www.prosci-inc.com/fkbp3-antibody-22-545.html WB: ,1:500 - 1:2000

APPLICATIONS: IF: ,1:50 - 1:100

IP: ,1:50 - 1:100

POSITIVE CONTROL: 1) HeLa

2) MCF-7

3) BT-474

PREDICTED MOLECULAR Observed: 30kDa WEIGHT:

Properties

PURIFICATION: Affinity purification

CLONALITY: Polyclonal

ISOTYPE: IgG

CONJUGATE: Unconjugated

PHYSICAL STATE: Liquid

BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

STORAGE CONDITIONS: Store at -20˚C. Avoid freeze / thaw cycles.

Additional Info

OFFICIAL SYMBOL: FKBP3

FKBP3, 25 kDa FK506-binding protein, 25 kDa FKBP, FKBP-3, Immunophilin FKBP25, FK506- ALTERNATE NAMES: binding protein 3, FK506-binding protein 3 (25kD), PPIase FKBP3, Rapamycin binding protein, Rotamase, PPIase, FK506 binding protein 3, 25kDa, FKBP-25, FKBP25

GENE ID: 2287

USER NOTE: Optimal dilutions for each application to be determined by the researcher.

Background and References

The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the BACKGROUND: immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.

September 29, 2021 2 https://www.prosci-inc.com/fkbp3-antibody-22-545.html ANTIBODIES FOR RESEARCH USE ONLY.

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September 29, 2021 3 https://www.prosci-inc.com/fkbp3-antibody-22-545.html