Rabbit Anti-LOX Monoclonal Antibody, Clone FQS5136 (DCABH-5958) This Product Is for Research Use Only and Is Not Intended for Diagnostic Use

Rabbit Anti-LOX monoclonal antibody, clone FQS5136 (DCABH-5958) This product is for research use only and is not intended for diagnostic use.

PRODUCT INFORMATION

Product Overview Rabbit monoclonal to LOX

Antigen Description Responsible for the post-translational oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin. In addition to cross-linking of extracellular matrix proteins, may have a direct role in tumor suppression.

Immunogen Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human LOX aa 350 to the C-terminus (Cysteine residue). The exact sequence is proprietary.Database link: P28300

Isotype IgG

Source/Host Rabbit

Species Reactivity Mouse, Rat, Human

Clone FQS5136

Purity Immunogen affinity purified

Conjugate Unconjugated

Applications WB, IHC-P, ICC/IF, IP, Flow Cyt

Positive Control HeLa, Jurkat and WI-38 cell lysates. Human muscle tissue. HeLa cells. Immunoprecipitation pellet from WI-38 cells lysate.

Format Liquid

Size 100 μl

Buffer pH: 7.2; Preservative: 0.01% Sodium azide; Constituents: 50% Glycerol, 49% PBS, 0.05% BSA

Preservative 0.01% Sodium Azide

Storage Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.

Ship Shipped at 4°C.

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Gene Name LNX1 ligand of numb-protein X 1, E3 ubiquitin protein ligase [ Homo sapiens ]

Official Symbol LNX1

Synonyms LNX1; ligand of numb-protein X 1, E3 ubiquitin protein ligase; ligand of numb protein X , ligand of numb protein X 1 , LNX; E3 ubiquitin-protein ligase LNX; MPDZ; PDZRN2; numb-binding protein 1; PDZ domain-containing ring finger protein 2; multi-PDZ-doma

Entrez Gene ID 84708

Protein Refseq NP_001119800

UniProt ID Q8TBB1

Chromosome Location 4q12

Pathway Notch signaling pathway, organism-specific biosystem;

Function PDZ domain binding; ligase activity; metal ion binding; protein binding; ubiquitin-protein ligase activity; zinc ion binding;

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]