Fibroids Uterine

3RD CONGRESS OF THE SOCIETY SEUD OF ENDOMETRIOSIS AND UTERINE DISORDERS Congress

201 7

& UTERINE FIBROIDS BLEEDING: UNLOCKING2017 THE ISSUES APRIL 6, 7, 8 SINGAPORE

Location Congress President SEUD President SUNTEC Convention Pr Yoke Fai Fong, Singapore Pr Charles Chapron, France & Exhibition Centre, Singapore

WWW.SEUD.ORG

TABLE OF CONTENTS

02 WELCOME LETTER 03 FACULTY & INTERNATIONAL COMMITTEE 04 PROGRAM AT A GLANCE SCIENTIFIC PROGRAM 06 WEDNESDAY, APRIL 5TH 07 THURSDAY, APRIL 6TH 08 FRIDAY, APRIL 7TH 12 SATURDAY, APRIL 8TH 14 PARTNERS 16 EXHIBITION MAP WELCOME TO SINGAPORE

Dear friends and colleagues,

It is with great pleasure that I welcome you to join us in Singapore in 2017 for the SEUD Congress. This is the third meeting for this exciting Congress and the first time it will be held in Asia, from April 6th - 8th 2017.

Singapore is in the heart of Asia, with Changi Airport having more than 100 airlines flying to some 330 cities in about 80 countries and territories worldwide. Singapore is distinctive in combining the best of East meets West, with a modern and efficient infrastructure, yet very much retaining the uniqueness and charm of Asian culture.

The theme for the 2017 Congress is “Fibroids and uterine bleeding: unlocking the issues”. Up to a third of women have fibroids and many more have some form of abnormal uterine Boards bleeding during their lifetime. It is an appropriate opportunity for us to unlock the issues and controversies and we have the privilege to host internationally renowned speakers known for Congress their expertise at this meeting. President Yoke Fai Fong Not forgetting the ideals of our first two Congresses, we will still continue to feature both Co-chairs Endometriosis and Adenomyosis in the scientific program. The width, breadth and depth of the Sun Wei Guo topics to be discussed, with live surgeries, key note lectures, plenaries, debates, workshops, Jim Tsaltas National sessions etc, will certainly make this a very exciting Congress for its high level Local organizing scientific content. committee Anupriya Agarwal Singapore is the springboard to the regional countries and itself is a unique and exciting Nainda Calustre tourist destination. The Congress venue itself is in the heart of the city, with the famous Karen Lim Marina Bay as the backdrop, and the Gala Dinner itself will be held at the Gardens by the Bay, Harvard Lin an attraction that has won multiple awards such as the THEA award, World Building of the Year Li Ma award, TripAdvisor Travellers’ choice awards and many more. Kai Lyn Ng Ying Woo Ng We look forward to seeing you here in 2017. Judith Ong Bharti Parikh Shakina Rauff Pr Yoke Fai Fong Meilan Xie President of the 3rd SEUD Congress

2 SEUD Congress RD WELCOME TO SINGAPORE 3 CONGRESS OF THE SOCIETY OF ENDOMETRIOSIS AND UTERINE DISORDERS 201 7

Faculty & international committee Mauricio Abrao, Brazil Ian Fraser, Australia Alex Ooi, Singapore Anupriya Agarwal, Singapore Caroline Gargett, Australia Yutaka Osuga, Japan Angela Aguilar, Philippines Sun-Wei Guo, China Yoshiaki Ota, Japan Saeed Alborzi, Iran Wachyu Hadisaputra, Indonesia Resad Pasic, USA Masaaki Andou, Japan Tasuku Harada, Japan Felice Petraglia, Italy Suan Tiong Beh, Singapore Andon Hestiantoro, Indonesia Paola Piomboni, Italy Arijit Biswas, Singapore Sarah Holdsworth-Carson, Australia Alexander Popov, Russia Giuliano Borrelli, Brazil Tew Hong Ho, Singapore Jaron Rabinovici, Israel Serdar Bulun, USA Kathy Huang, USA Yunyun Ren, China German Tan Cardoso, Philippines Khaleque Khan, Japan Peter Rogers, Australia Francisco Carmona, Spain Rosanne M. Kho, USA Juan L. Salgado, Puerto Rico Amphan Chalermchokcharoenkit, Thailand Chit Chong Khong, Singapore Pietro Santulli, France Cathryn Chan, Singapore Su-Yen Khong, Malaysia Kaiyin See Tho, Singapore Jerry Chan, Singapore Chong Kiat Khoo, Singapore Gamal Serour, Egypt Charles Chapron, France Sung Hoon Kim, Korea Sony Singh, Canada Miguel Angel Checa, Spain Chung Fai Koh, Singapore Edgardo Somigliana, Italy Jin-Yun Chen, China Alka Kriplani, India Elizabeth Stewart, USA Yi Jen Chen, Taiwan Philippe Y. Laberge, Canada Ann Tan, Singapore Zi-Jiang Chen, China Keen Whye Lee, Singapore Yew Ghee Tan, Singapore Bernard Chern, Singapore Jin Hua Leng, China Maruyama Tetsuo, Japan Vincent Cheung, Hong Kong Susan Logan, Singapore Jim Tsaltas, Australia Si Hyun Cho, Korea Anne-Elodie Millischer, France Peng-Hui Wang, Taiwan Kah Kiong Chow, Singapore Malcom Munro, USA Lip Kee Yap, Singapore Hilary Critchley, United Kingdom Suresh Nair, Singapore Eu-Leong Yong, Singapore Magrit Dueholm, Denmark Haider Najjar, Australia Scott Young, USA Yoke Fai Fong, Singapore Soon Chye Ng, Singapore Su Ling Yu, Singapore Hervé Fernandez, France Ying Woo Ng, Singapore Xin Mei Zhang, China

3 PROGRAM AT A GLANCE

WEDNESDAY, APRIL 5TH THURSDAY, APRIL 6TH 07:30

08:00 WELCOME DESK OPENING 08:30 Welcome coffee S 09:00 A 331 09:30 MYOMECTOMY WORKSHOPS SIMULTANEOUS ALGERIAN Myomectomy morning course LIVE SURGERIES SESSION 10:00 SPONSORED BY FROM NATIONAL UNIVERSITY HOSPITAL 10:30

11:00 Coffee break 328 331 333 A 11:30 JAPANESE CHINESE INDIAN SESSION SESSION SESSION 12:00 MYOMECTOMY WORKSHOPS

Myomectomy morning course S BENIGN 12:30 GYNAECOLOGICAL Cocktail lunch CONDITIONS… & exhibition visit 13:00 S Lunch OPENING CEREMONY 13:30 B S KEYNOTE LECTURE STATE OF THE ART Uterine fibroids: impact on women’s health 14:00 ON THE IMAGING A DIAGNOSIS OF ENDOMETRIOSIS S 14:30 AND ADENOMYOSIS SPONSORED BY PATHOGENESIS OF UTERINE FIBROIDS 15:00

15:30 MYOMECTOMY WORKSHOPS Coffee break Myomectomy hands-on session Coffee break & exhibition visit B 16:00

STATE OF THE ART S 16:30 ON THE IMAGING DIAGNOSIS OF ENDOMETRIOSIS AND ADENOMYOSIS 17:00 ADENOMYOSIS: WELCOME FROM DIAGNOSIS TO MODERN MANAGEMENT DESK OPENING 17:30 AT SUNTEC

18:00

18:30 Welcome reception & posters visit

19:00

A Venue: S Advanced Surgery Training Centre (ASTC) National University Hospital SUMMIT 1 (PLENARY ROOM) 327 328 … ROOMS 327, 328… B Venue: Seminar Room T12-03, National University Health System Tower Block Level 12 4 SEUD Congress RD 3 CONGRESS OF THE SOCIETY OF ENDOMETRIOSIS AND UTERINE DISORDERS 201 7

FRIDAY, APRIL 7TH SATURDAY, APRIL 8TH 07:30

S 08:00 328 S UTERINE FIBROIDS: 328 NEW THERAPEUTIC DEVELOPMENT 08:30 NEW TOOLS IN ENDOMETRIOSIS FIELDS LATIN SPONSORED BY RUSSIAN AMERICAN 09:00 SESSION SESSION

09:30 S KEYNOTE LECTURE Endometriosis management: time to reconsider the paradigm S KEYNOTE LECTURE 10:00 HMB, the symptom, the hormonal therapies and integral supplemental medication Coffee break & exhibition visit S 327 328 331 332 10:30

S 327 328 331 332 333 FREE FREE FREE FREE Coffee break CELEBRATING WOMEN, VIDEOS COM. COM. COM. COM. 11:00 TRANSFORMING LIVES SESSION 10 11 12 13 FREE FREE FREE FREE FREE COM. COM. COM. COM. COM. Coffee break & exhibition visit 11:30 S 1 2 3 4 5 NEW MODALITIES S 331 IN HAEMOSTASIS DEBATE 12:00 DEBATE Medical treatment of uterine Infertility and DIE: surgery first or ART? fibroids as first line therapy: yes or no? 12:30 S 331 DEBATE 328 DEBATE The world should just ignore S Fresh the FDA advisory and carry on with 13:00 versus frozen transfer UTERINE FIBROIDS AND INFERTILITY morcellation of fibroids / large uteri APAGE SPONSORED BY SESSION S BREAKING DOWN 13:30 THE PATHWAY TO PAIN MANAGEMENT IN ENDOMETRIOSIS Cocktail lunch & exhibition visit 14:00 SPONSORED BY S AWARDS & CLOSING CEREMONY 14:30 S SEUD ASSEMBLY 15:00 S 327 331 332 333 328 331 332 TRUCLEAR / A MINIMALLY INVASIVE OPTION FREE FREE FREE FREE CANADIAN 15:30 FOR ADDRESSING… COM. COM. COM. COM. SESSION 6 7 8 9 SPONSORED BY PATIENTS SESSION 16:00 Coffee break & exhibition visit 16:30 S 327 17:00

ABNORMAL UTERINE BLEEDING (AUB): MIDDLE EAST HOW “PALM-COEIN” HELPS US MANAGE OUR PATIENTS SESSION 17:30

18:00

SEUD social evening at the Gardens by the Bay (shuttle departure) 18:30

SPONSORED BY

19:00

5 SCIENTIFIC PROGRAM

WEDNESDAY, APRIL 5TH

PRE-COURSES (compulsory registration)

08:30 Myomectomy workshops SPONSORED BY 13:00 State of the art SPONSORED BY 17:00 Organizer: Yoke Fai Fong (Singapore) 17:30 on the imaging diagnosis Venue: Advanced Surgery Training Centre (ASTC) of endometriosis and adenomyosis National University Hospital Chairs: Mauricio Abrao (Brazil) 08:30 Registration & breakfast & Arijit Biswas (Singapore) 09:00 Myomectomy morning course Venue: National University Health System NUHS Tower Block Welcome address, Yoke Fai Fong (Singapore) 13:00 Registration & lunch - How to reduce bleeding at myomectomy? 13:30 Welcome address, Mauricio Abrao (Brazil) Yoke Fai Fong (Singapore) & Arijit Biswas (Singapore) - Atypical locations: cervical and broad - TVS US versus MRI for the diagnosis ligament fibroids, Alexander Popov (Russia) of endometriosis: which is the best method? - Laparoscopic myomectomy and risk of uterine rupture, Anne-Elodie Millischer (France) Vincent Cheung (Hong Kong) - TVS in diagnosis of DIE at different locations, - Different methods of specimen retrieval, Scott Young (USA) Francisco Carmona (Spain) - Interpretation of MRI for DIE, - Laparoscopic myomectomy for large fibroids, Anne-Elodie Millischer (France) Masaaki Andou (Japan) - Imaging modalities for adenomyosis - Questions & answers (2D TVS, 3D TVS, MRI), Giuliano Borrelli (Brazil) 10:40 Coffee break - Questions & answers - Surgical treatment of adenomyosis / adenomyoma: 15:20 Coffee break tips and tricks, Yoshiaki Ota (Japan) - Use of imaging to guide surgical approach (US), - Video masterclass: laparoscopic hysterectomy Juan L. Salgado (Puerto Rico) for huge fibroids, Masaaki Andou (Japan) - Use of imaging to guide surgical approach (MRI), - Video masterclass: tips and tricks on how to manage Kathy Huang (USA) multiple myomas, Wachyu Hadisaputra (Indonesia) - Use of Imaging for surveillance of endometriosis, - Video masterclass: hysteroscopic resection, Mauricio Abrao (Brazil) Peng-Hui Wang (Taiwan) Live scanning demonstration - Video masterclass: tips & tricks, Chair: Rosanne M. Kho (USA) Francisco Carmona (Spain) - Live scanning, Scott Young (USA) - Questions & answers 16:30 Welcome desk opening at SUNTEC 13:00 Lunch 18:00 Onsite registration 14:00 Myomectomy hands-on session SUNTEC and receipt of badges. - In bag morcellation with rotocut - In bag morcellation with coldknife - Haemostasis with advanced energy - 2D versus 3D suturing - Hysteroscopic resection - Intrauterine Bigatti Shaver (IBS) - Knotless Tissue Control - Trophyscope for hysteroscopy

6 SEUD Congress RD 3 CONGRESS OF THE SOCIETY OF ENDOMETRIOSIS AND UTERINE DISORDERS 201 7

THURSDAY, APRIL 6TH

07:45 Welcome desk opening - Is mesosalpinx important for ovarian blood supply? 08:30 Onsite registration and receipt of badges. Learning from our experiences in ovarian reserve after surgery for endometriosis and salpingectomy, 08:30 Simultaneous live surgeries Akira Iwase (Japan) 12:00 from National University Hospital - Estrogen actions that contribute to develop SUMMIT 1 First operating theater endometriosis, Taisuke Mori (Japan) - Long endometriosis case - Lipopolysaccharide promotes the development Surgeon: Arnaud Wattiez (France) of murine endometriosis-like lesions via the nuclear Second operating theater factor-kappa B pathway, Fuminori Taniguchi (Japan) - Single port myomectomy - Epigenetically repressed microRNAs promote Surgeon : Yoke Fai Fong (Singapore) the pathogenesis of endometriosis, Kaei Nasu (Japan) - Simple hysterectomy - Research platform focusing on endometriotic Surgeon: Masaaki Andou (Japan) epithelial cells, Tetsuya Hirata (Japan) 08:30 1st part 11:00 Chinese session Chairs: Mauricio Abrao (Brazil), 12:30 Chairs: Hua Duan & Chii-Ruey Tzeng (Taiwan) Keen Whye Lee (Singapore) & Jim Tsaltas (Australia) ROOM 331 (English-speaking session)

nd - The relationship between the epigenetics 10:30 2 part of eutopic endometrium and endometriosis-associated Chairs: Rosanne M. Kho (USA), Haider Najjar (Australia) ovarian cancer, Danbo Wang (Shenyang, China) & Kaiyin See Tho (Singapore) - Peritoneal fluid: an important sign for management 09:00 Algerian session of infertile women with endometriosis, 10:30 Chair: Mourad Bounif (Algeria) Shun-Jen Tan (Taipei, Taiwan) ROOM 331 (French-speaking session) - New insights into macrophages in endometriosis: - Imaging in adenomyosis, Abdenour Youcef Khodja differentiation and function, Xiaoyong Zhu (Algeria) (Shanghai, China) - Adenomyosis management in infertility, - Assessment of a panel of serum cytokines Nefissa Lakhdara & Amel Dammene Debbih (Algeria) and chemokines as potential markers - Myomectomy by hysteroscopy without energy by HEOS of endometriosis, Ya-Ching Chou (Taipei, Taiwan) Algerian experience, Farid Benaibouche - Gene regulation in endometriosis, Qing Xue & Nefissa Lakhdara (Algeria) (Beijing, China) - Management of submucous myomectomy - Tubal endometriosis and its impact on fertility, our experience, Farid Benaibouche Jian Zhang (Shanghai, China) & Nefissa Lakhdara (Algeria) 11:00 Indian session - Endometriosis in all its forms in the maternity 12:30 Videos session (Sidi belabbes experience), ROOM 333 (English-speaking session) Fadlallah Aboubekr & Yacine Benmoumen (Algeria) - Complications of surgery for severe endometriosis, - Does laparoscopy useful in infertility management? Vidya Bhat (India) Mokrane Medjtoh (Algeria) - Conservative surgical management of adenomyosis, - Dysfunctionel uterine bleeding evaluation Rekha Kurien (India) of two therapeutics SIU LNG Vs TCRE (140 cases), - Laparoscopic management Yacine Benmoumen & Fadlallah Aboubekr (Algeria) of severe endometriosis, Vivek Marwari (India) - Management of the adenomyosis, Racim Khodja (Algeria) - Surgery for AUB, Kunju Mohideen (India) - Results of 6 years of laparoscopic surgery 11:50 Panel discussion (Blida experience), Ismail Larbi & Nouhad Belilet (Algeria) on uterine disorders and endometriosis 11:00 Japanese session Chairs: Kanthi Banzal & T. Ramani Devi (India) 12:30 Chairs: Tasuku Harada & Yutaka Osuga (Japon) Speakers: Kalpana Balamurugan, Santhanagopalan Chitra, ROOM 328 (English-speaking session) Tejas Dave, Sampath Kumari, Sripriya Pragasam - Hypoxia induces hypoxia inducible factor-1α (HIF-1α) & Nita Thakre (India) and its related gene expression in uterine leiomyoma, Hiroshi Ishikawa (Japan) 7 SCIENTIFIC PROGRAM

THURSDAY, APRIL 6TH FRIDAY, APRIL 7TH

12:00 Benign gynaecological 08:00 Uterine fibroids: SPONSORED BY 13:00 conditions: ironing 09:30 new therapeutic development SUMMIT 1 out the iron deficiency SUMMIT 1 Chairs: Susan Logan (Singapore) (lunch boxes will be provided) & Elizabeth Stewart (USA) Chairs: Ian Fraser (Australia) & James Isbister (Australia) - Distinguishing uterine fibroids from adenomyosis: - Welcome, Ian Fraser & James Isbister (Australia) sonographic features of myometrium / uterine - Total management of women suffering from gynecological masses - MUSA Consensus (Morphological conditions, Jason Abbott (Australia) Uterus Sonographic Assessment (MUSA) group, - What does “Patient Blood Management” have to offer Magrit Dueholm (Denmark) for women with with abnormal uterine bleeding (AUB)? - The utility of ultrasonic elastography Axel Hofmann (Austria) in diagnosing adenomyosis and uterine fibroids: - Questions & answers theory and clinical practice, Yunyun Ren (China) - Stem cell of uterine fibroids and bioengineering 12:00 Cocktail lunch & exhibition visit uterine tissue for repair, Maruyama Tetsuo (Japan) 13:00 Opening Ceremony - Is MRgFUS a good option for women with uterine 13:30 Speakers: Charles Chapron (France) fibroids desiring pregnancy? Jaron Rabinovici (Israel) SUMMIT 1 & Yoke Fai Fong (Singapore) 08:00 Russian session 13:30 Keynote lecture 10:00 Chairs: Vera Balan & Alexandr Popov (Russia) 14:00 Chairs: Charles Chapron (France) ROOM 328 (Russian-speaking session) SUMMIT 1 & Yoke Fai Fong (Singapore) - Pharmacological therapy of uterine fibroids: realities Uterine fibroids: impact on women’s health, and perspectives, Mariya Yarmolinskaya (Russia) Elizabeth Stewart (USA) - UAE and MRgFUS: pro and con - What a doctor should know, Yulia Kurashvili (Russia) 14:00 Pathogenesis of uterine fibroids - The experience of 1500 myomectomy cases: 15:30 Chairs: Yutaka Osuga (Japan) the failures of laparoscopic myomectomy and how SUMMIT 1 & Eu-Leong Yong (Singapore) to overcome them, Konstantin Puchkov (Russia) - Sex steroids hormones and uterine fibroids, - The principles of prophylaxis of obstetric Serdar Bulun (USA) complications in laparoscopic myomectomy, - Modulation of neoangiones is in uterine fibroids, Vitaly Bezenar (Russia) Sarah Holdsworth-Carson (Australia) - Uterus myoma and reproduction, - Extracellular matrix and uterine fibroids, Yulia Dobrohotova (Russia) Felice Petraglia (Italy) - Questions & answers - Efficacy and safety of the new Progesterone Receptor Modulator vilaprisan – data from the phase 2 program, 09:30 Keynote lecture Sony Singh (Canada) 10:00 Chairs: Tasuku Harada (Japan) & Felice Petraglia (Italy) SUMMIT 1 Endometriosis management: time to reconsider 15:30 Coffee break & exhibition visit the paradigm, Charles Chapron (France) 16:00 Adenomyosis: from diagnosis 10:00 Coffee break & exhibition visit 18:00 to modern management SUMMIT 1 Chairs: Hilary Critchley (United Kingdom) 10:30 Celebrating women, & Sun-Wei Guo (China) 11:30 transforming lives - Diagnosis optimization with imaging process, SUMMIT 1 Chairs: Raman Subramaniam (Malaysia), Mauricio Abrao (Brazil) Su Ling Yu (Singapore), Hervé Fernandez (France), - Pain and bleeding management for adenomyotic Bernard Chern (Singapore), & Yi Jen Chen (Taiwan) st patients, Tasuku Harada (Japan) - Celebrating with the 1 oral therapy for smptomatic - Adenomyosis related infertility: modern treatment, uterine fibroids, Hervé Fernandez (France) Zi-Jiang Chen (China) - Questions & answers - HIFU treatment for adenomyosis, Jin-Yun Chen (China) - Panel discussion on experiences with Esmya 18:00 Welcome reception & posters visit

8 SEUD Congress RD 3 CONGRESS OF THE SOCIETY OF ENDOMETRIOSIS AND UTERINE DISORDERS 201 7

FRIDAY, APRIL 7TH

10:30 Free communications - Periperative management of myoma type I and II 12:30 Free communications 1 in infertile women; an Algerian retrospective experience, ROOM 327 Chairs: Miguel Angel Checa (Spain) & Ann Tan (Singapore) Farid Benaibouche (Algeria) - Extra genital endometriosis, 3 cas reports, - Influence of adenomyosis on pregnancy outcome an Algerian teaching hospital retrospective experience, and first and second trimester markers of impaired Nefissa Lakhdara (Algeria) placentation in women with endometriosis, - Co-morbidity, inter-current infections and hormonal Ferrero Simone (Italy) differences among women with and without intra-uterine - Endometriosis and obstetric outcomes among adhesions seeking assisted reproduction in Nigeria, nulliparous women: an unicentric retrospective cohort Abayomi Ajayi (Nigeria) study, Louis Marcellin (France) - Uterine fibroid surgery – impact on reproduction, - Reproductive effects of endometriosis Alexander Popov (Russia) in the spontaneous abortion model of CBA/J×DBA/2 - Influence of ovarian endometriosis mice, Louis Marcellin (France) on ovarian-responsiveness to hyperstimulation: - Not having been breastfed may be a potential an AMH-matched controlled study, Jade Raad (France) protective factor against developing deep infiltrating - Benefice of hysteroscopy for implantation failure endometriosis among Chinese women: results from with endometrial scratch and biopsy prior to ART a subgroup analysis of the Feeling study, Yi Dai (China) second attempt, an Algerian retrospective experience, - Arteriovenous malformation of the uterus – 4 case Nefissa Lakhdara (Algeria) reports, Jiri Hanacek (Czech Republic) - Endometrial preparation:impact of estrogen duration of administration before frozen-thawed blastocyst ROOM 331 Free communications 3 Chairs: Ying Woo Ng (Singapore) & Xin Mei Zhang (China) transfer on live birth rate, Pietro Santulli (France) - Live birth rate following frozen-thawed embryo - Bioinformatic analysis of transcriptomic data identifies transfer is higher for day 5 than day 6 blastocysts, miRNAS relevant for endometriosis pathogenesis, Bruno Borghese (France) Pietro Santulli (France) - Dienogest cycle synchronization for in vitro fertilization - Methylome genomewide analysis unveils the role in women with deep infiltrating endometriosis, of estrogen-related genes in ovarian endometrioma, Bruno Borghese (France) Claudia Tosti (Italy) - One-year follow-up of serum antimüllerian hormone - Low plasma soluble TNFR1 levels in symptomatic levels in patients with laparoscopic ovarian women with endometriosis, Fernando M. Reiz (Brazil) cystectomy, Yan Ding (China) - Gene and protein expression of HLA-G in deep - Successive fertility following optimized perfusion endometriosis, Maurício Simões Abrão (Brazil) and cryopreservation of whole ovary - Evaluating the impact of chronic pelvic pain and allotransplantation in a premature ovarian failure on women’s lives:what we learned from focus group Ooi Thye Chong (United Kingdom) rat model, Yan Ding (China) discussions, - A case if deep infiltrating endometriosis requiring - Comparative proliferative activity of ectopical endometrial ureteric resection, psoas hitch and ureteric cells in patients with primary and recurrent Svetlana Dubrovina (Russia) preimplantation, Harvard Lin (Singapore) endometriomas, - Impact of peritoneal fluid ceramides on endometriosis ROOM 328 Free communications 2 associated infertility (EAI), Lee Yie Hou (Singapore) Chairs: Cathryn Chan (Singapore) - Neurokinin 1 receptor (NK1R) Antagonism suppresses & Vincent Cheung (Hong Kong) the development of endometriosis, Dingmin Yan (China) - First live birth following removal of super giant myoma - Infliximab effect on immune response and intravenous leiomatosis, Ali Farid Mohamed Ali (Egypt) in endometriosis model rats sprague dawley, - Laparoscopic niche correction – reproductive results, Syarief Thaufik Hidayat (Indonesia) Anton Fedorov (Russia) - Role of matrix metalloproteinases and their tissue - Preconceptional cervical cerclage after second and third inhibitors in spread of endometriosis, trimester pregnancy loss, Anton Fedorov (Russia) Maryia Paulouskaya (Belarus) - Pregnancy outcome in infertile women with previous - Surgical conservative management for treatment laparoscopic myomectomy, Arif Tunjungseto (Indonesia) of adenomyosis: conservative adenomyomectomy, - Uterine fibroids and prematurity: a retrospective cohort Gracia Meritxell (Spain) study, Louis Marcellin (France) 9 SCIENTIFIC PROGRAM

FRIDAY, APRIL 7TH

ROOM 332 Free communications 4 - Impact of the SPRM ulipristal acetate upon Chairs: Chong Kiat Khoo (Singapore) & Resad Pasic (USA) endometrial gene expression and cell proliferation, - Follow-up of MRI deep infiltrative endometriotic Lucy Whitaker (United Kingdom) lesions before and after pregnancy: does it change - Influence of diet on development of fibroids something? Anne-Elodie Millischer (France) and endometiosis, analysis of the National health - Laparoscopic management of multiple site intestinal and nutrition examination survey, Olga Bougie (Canada) endometriosis, Ichikawa Fuyuki (Japan) - New regimen options using ulipristal acetate - A randomized double blind placebo controlled study for symptomatic fibroids: impact of age non the effect of claritrhomycin on clonics on the indication of the regimen, Paula Fabra (Spain) and paraclinics of paients with severe endometriosis - Symptomatology and Patient preferences among after laparoscopic surgery, Saeed Alborzi (Iran) canadian women presenting with symptomatic uterine - What is the best medication to prevent post-operative fibroids, Philippe Laberge (Canada) recurrence of endometrioma in the long term? - Efficacy and safety of the new progesterone receptor Yoshiaki Ota (Japan) modulator vilaprisan – data from the phase 2 program, - Caloric restriction dramatically hinders the lesion Sony Singh (Canada) growth in mouse with experimentally induced - Peritoneal fluid 13-HODE as a potential angiogenesis endometriosis, Bo Yin (China) regulating oxylipin in endometriosis, Lee Yie Hou (Singapore) - Acetate UPA in infertile women’s management with endometriosis and adenomyosis, 11:30 New modalities Jean-Philippe Estrade (France) 12:30 in haemostasis - Effectiveness of prolonged use of dienogest SUMMIT 1 - Good clinical pratice for TLH in myoma uteri, 2 mg in patients with endometriosis, Amphan Chalermchokcharoenkit (Thailand) Maria Yarmolinskaya (Russia) - The technical background of argon - Rapid and sustained improvement in dysmenorrhea plasma coagulation (APC), Fritz Maier (Singapore) and non-menstrual pelvic pain with elagolix treatment - APC in gynecology surgery, Yoke Fai Fong (Singapore) in women with endometriosis-associated pain, 12:30 Debates Maurício Simões Abrão (Brazil) 13:15 (simultaneous sessions) - A study of the clinical impact of a three month SUMMIT 1 Chairs: Anupriya Agarwal (Singapore) pre-operative course of ulipristal acetate in subjects & Andon Hestiantoro (Indonesia) with known pelvic endometriosis, Paul D. Simpson Fresh versus frozen transfer (United Kingdom) - Edgardo Somigliana (Italy) - Long-term treatment dienogest - Miguel Angel Checa (Spain) in adolescent endometriosis associated pain, ROOM 331 Chairs: Amphan Chalermchokcharoenkit (Thailand) Syarief Thaufik Hidayat (Indonesia) & Su-Yen Khong (Malaysia) ROOM 333 Free communications 5 The world should just ignore the FDA advisory Chairs: Caroline Gargett (Australia) and carry on with morcellation of fibroids / large uteri & Yew Ghee Tan (Singapore) - Rosanne M. Kho (USA) - Difficulties of laparoscopic myomectomy and ways - Kathy Huang (USA) to overcome them, Puchkov Konstantin (Russia) 12:30 - Ulipristal acetate: a recently approved medical APAGE session 14:00 Chairs: Angela Aguilar (Philippines) treatment for fibroids, Amani Harris (Australia) - Clinical experience in the follow-up of patients ROOM 328 & Wachyu Hadisaputra (Indonesia) with symptomatic uterine fibroid treated with ulipristal (English-speaking session) - The spirit of MIS in endometriosis, Chyi-Long Lee (Taiwan) acetate: is it an alternative to surgery? Mariona Rius (Spain) - Clinical outcomes of using ulipristal acetate - Laparoscopic reconstructive surgery for ureteral in patients with symptomatic uterine fibroids and Intestinal endometriosis, Masaaki Andou (Japan) with or without concommitant adenomyosis: - The fertility consideration and laparoscopic myomectomy, Chih-Feng Yen (Taiwan) preliminary study, Gracia Meritxell (Spain) - Ulipristal acetate in women with symptomatic uterine miomes in a real-worl clinical setting, Pilar Lafuente (Spain) 10 SEUD Congress RD 3 CONGRESS OF THE SOCIETY OF ENDOMETRIOSIS AND UTERINE DISORDERS 201 7

FRIDAY, APRIL 7TH

13:15 Breaking down the pathway - Borderline sero papillary tumor on endometrioma, 14:15 to pain management in endometriosis Julien Bakenga (France) SUMMIT 1 (lunch boxes will be provided) - Unsuspected uterine sarcomas undergoing morcellation: - Challenges in assessing pain in endometriosis, a retrospective multicenter study, Oshri Barel (Australia) Sanjay Agarwal (USA) - Clinical analysis of ovarian epithelial carcinoma - Mechanisms of pain in endometriosis: in women with ovarian endometriosis aged 45 years from pathways to patients, Serdar Bulun (USA) and older in China, Zheng-Xing He (China) - Advancing pain management and control ROOM 332 Free communications 8 in endometriosis, Nicholas Leyland (USA) Chairs: Saeed Alborzi (Iran) 13:15 Cocktail lunch & exhibition visit & Kaiyin See Tho (Singapore) - An experience of surgical treatment for urogenital 14:30 SEUD Assembly endometriosis, Alexander Popov (Russia) 15:00 TRUCLEAR / A minimally - Alternative graft colpopexy, John Missanelli (USA) 16:00 invasive option for addressing: abnormal - A comparison between reduced-port robotic surgery SUMMIT 1 uterine bleeding and intrauterine pathology for myomectomy and multiport robot-assisted Chair: Keen Whye (Lee Singapore) laparoscopic myomectomy, Kim Woo Young (Korea) - Abnormal uterine bleeding - Asia prevalence - Influence of race/ethnicity on route of hysterectomy and management strategy, Toh Lick Tan (United Kingdom) and inpatient surgical complications, - My experience with TRUCLEAR in hysteroscopic Olga Bougie (Canada) removal of polyps and fibroids in an outpatient - Advantages of bilateral occlusion of uterine arteries “clinic/office”, Justin Clark (United Kingdom) during laparoscopic myomectomy, Pietro Litta (Italy) - Questions & answers ROOM 333 Free communications 9 15:00 Free communications Chairs: Sarah Holdsworth-Carson (Australia) 16:00 Free communications 6 & Malcom Munro (USA) ROOM 327 Chairs: Anne-Elodie Millischer (France) - Safety and efficacy of the selective progesterone & Eng Hseon Tay (Singapore) receptor modulator asoprisnil for heavy menstrual - Ultrasound changes of adenomyosis during hormonal bleeding with uterine fibroids: pooled analysis contraceptives, Angelo Cagnacci (Italy) of two 12-month, placebo-controlled, randomized - Transvaginal sonoelastographic diagnosis trials, Kristof Chwalisz (USA) of adenomyosis: a comparison with the B-mode - Effective and rapid control of bleeding with elagolix ultrasonography and its association with clinical with or without add-back therapy in women with heavy features, Ding Ding (China) menstrual bleeding associated with uterine fibroids, - Long-term outcomes of high-intensity focused Charlotte Owens (USA) ultrasound ablation for adenomyosis: a retrospective - Adenomyosis arising in 20-year-old woman cohort study, Jinyun Chen (China) after uterine perforation –Study on the possible - Classification of adenomyosis by MR image analysis pathogenesis, Ritsuo Honda (Japan) and pathology, Ota Ikuko (Japan) - Efficacy and safety of ultrasound-guided - Three-dimensional ultrasound of adenomyosis: high-intensity focused ultrasound in the treatment morphological findings, their diagnostic value of uterine fibroids: a prospective cohort study, and their correlation with MRI and histopathology, Vincent Y.T. Cheung (Hong Kong) Tina Tellum (Norway) - Research of gestrinone - related abnormal uterine bleeding and the intervention in the treatment: ROOM 331 Free communications 7 a multi-center, randomized, controlled clinical trial, Chairs: Tew Hong Ho (Singapore) & Sung Hoon Kim (Korea) Wang Sha (China) - The incidence of polycystic ovarian syndrome is not decreased in women suffering from endometriosis, Chloe Tran (France) - A five-year prevalence and characteristics of polycystic ovary syndrome (PCOS) in Filipino women diagnosed with endometrial cancer, Genevieve M. Ortega (Philippines) 11 SCIENTIFIC PROGRAM

FRIDAY, APRIL 7TH SATURDAY, APRIL 8TH

15:00 Canadian session SPONSORED BY 07:45 New tools in endometriosis fields 16:30 Fibroids: fertility sparing strategies 09:45 Chairs: Jerry Chan (Singapore) & Khaleque Khan (Japan) ROOM 328 Chair: Philippe Y. Laberge (Canada) SUMMIT 1 - Understanding endometriosis: genetic approaches, (English-speaking session) Peter Rogers (Australia) - Introduction, Philippe Y. Laberge (Canada) - Role of stem cells in endometriosis, - CAPTURE: a Canadian patient registry study, Caroline Gargett (Autralia) Philippe Y. Laberge (Canada) - Diagnostic and therapeutic potentials of microRNA - Hysteroscopic removal of fibroids: in endometriosis, Si Hyun Cho (Korea) state of the art, Claude Fortin (Canada) - Ovarian endometriomas and DIE: are they the same - Fibroids in the young woman: strategies for uterine disease entity or different? Sun-Wei Guo (China) preservation, Ally Murji (Canada) - Efficacy and safety of long-term dienogest treatment - Surgical management of fibroids in pregnancy, in Asian patients with endometriosis: data Sony Singh (Canada) from Korean multicenter study, Sung Hoon Kim (Korea) - Wrap-up, Philippe Y. Laberge (Canada) 08:00 Latin American session 16:00 Coffee break & exhibition visit 09:45 Chair: Juan L. Salgado (Puerto Rico) 16:30 Abnormal uterine bleeding (AUB): ROOM 328 (Spanish-speaking session) 18:00 how “PALM-COEIN” helps us - Double stappler technique for bowel endometriosis: how and why? Thiers Raymundo (Brazil) SUMMIT 1 manage our patients Chairs: Si Hyun Cho (Korea) & Gamal Serour (Egypt) - Conservative surgical treatment of adenomyosis, - Why are we getting the AUB classification all wrong? Francisco Carmona (Spain) Hilary Critchley (United Kingdom) - Transvaginal sonography with bowel prep: - Novel technique for correction of obstructive Can predict complexity of surgery for DIE? Juan L. Salgado (Puerto Rico) mullerian abnormalities, wYoke Fai Fong (Singapore) - AUB: managing iron deficiency anaemia, - Surgical and practical anatomy to endometriosis: Luiz Flavio Fernandes (Brazil) Alka Kriplani (India) tips and tricks, - Endometrial ablation: trends and troubles in 2017, 09:45 Keynote lecture Philippe Y. Laberge (Canada) 10:15 Chairs: Angela Aguilar (Philippines) 16:30 Middle East session SUMMIT 1 & Philippe Y. Laberge (Canada) 18:00 Arab endometriosis session HMB, the symptom, the hormonal therapies and integral supplemental medication, ROOM 327 Chair: Ghassan Lotfi (UAE) (English-speaking session) Ian Fraser (Australia) - Minimally invasive surgery in the management 10:15 Videos session of adenomyosis, Afaf Ismail (Egypt) 11:21 Chairs: Kah Kiong Chow (Singapore) & Kathy Huang (USA) - Approach to endometrioma infertility patients: SUMMIT 1 - Effect of total pelvic peritonectomy (including DIE facts and strategies, Hesham Arab (Saudi Arabia) lesion) in cases of deep infiltrative endometriosis (DIE) - Pre-and postoperative hormonal therapy: with intractable pain, Dogyun Kim (Korea) evidence for indications, Maryam Al Shukri (Oman) - The resurrection of the laparoscopic burch - Primary atypical dysmenorrhea in adolescents: colposuspension, Harvard Lin (Singapore) can survey be the path for future screening - Operative management of endometriosis with large of endometriosis? Moamar Al Jefout (UAE) bowel involvement at a large tertiary referral unit, 17:15 Current state of endometriosis Hugh O’Connor (Australia) in the region: panel discussion - Laparoscopic primary repair after the diaphragmatic - Presentation from each representative endometriosis resection, Joong Sub Choi (Korea) of six Arab countries: UAE, Saudi Arabia, Egypt, - Tips for safe and complete laparoscopic myomecotmy, Kuwait, Oman, Jordan Dogyun Kim (Korea)

18:00 SEUD social evening SPONSORED BY - A case of tubal reanastomosis, Li Ma (Singapore) at the Gardens by the Bay - Ressection of sciatic endometriosis nodule: (shuttle departure) report of 2 cases, Mariona Rius (Spain) - Surgical tips for robot-assisted isthmocele repair, 12 Seong Seok Ju (Korea) SEUD Congress RD 3 CONGRESS OF THE SOCIETY OF ENDOMETRIOSIS AND UTERINE DISORDERS 201 7

SATURDAY, APRIL 8TH

- Single port laparoscopic treatment of rectal - A four-year experience with bowel endometriosis, endometriosis, Yoon Soon Lee (Korea) Saeed Alborzi (Iran) - Laparoscopic shaving for deep endometriosis nodule, Jean-Philippe Estrade (France) ROOM 332 Free communications 13 - Stepwise approach to the rectovaginal nodule, Chairs: Chung Fai Koh (Singapore) & Jin Hua Leng (China) Olga Bougie (Canada) - Experience in the use of agonists GnRH in the chronic pelvic pain syndrome caused by adenomyosis, 10:15 Free communications Marina Khamoshina (Russia) 11:15 Free communications 10 - Does NETosis in endometriosis depend on the stage ROOM 327 Chairs: Chit Chong Khong (Singapore) of endometriosis progression? Yunlei Cao (China) & Yoshiaki Ota (Japan) - Higher prevalence of fibromyalgia in deep infiltrating - Vaginal bromocriptine improves pain and bleeding endometriosis patients, Francisco Carmona (Spain) in women with adenomyosis, Johanna Andersson (Sweden) - Epigenetic regulation of endometriosis-associated - Dysmenorrhea in patients with adenomyosis: pain, Nalini Santanam (USA) a clinical and demographic study, Qing Li (China) - Multiple histeroscopic miomectomy in adenomiotic uterus - Evaluation of the therapeutic effects of different after ulipristal acetate treatment, Mariona Rius (Spain) low doses of mifepristone on adenomyosis women 11:15 Coffee break & exhibition visit with dysmenorrhea, Xinmei Zhang (China) - Neutralization of TGF-β1 signaling reduces myometrial 11:45 Debates infiltration and alleviates generalized hyperalgesia 12:30 (simultaneous sessions) in mice with induced adenomyosis, Xishi Liu (China) SUMMIT 1 Chairs: Suresh Nair (Singapore) & Sony Singh (Canada) - Study on the efficacy of a gossypol acetate-loaded Infertility and DIE: surgery first or ART? intrauterine contraceptive device on experimental - Surgery, Francisco Carmona (Spain) adenomyosis, Zhu Libo (China) - ART, Pietro Santulli (France)

ROOM 328 Free communications 11 ROOM 331 Chairs: Serdar Bulun (USA) & Alexander Popov (Russia) Chairs: Peter Rogers (Australia) & Su Ling Yu (Singapore) Medical treatment of uterine fibroids - Impact of dienogest on endometriomas ultrasonographic as first line therapy: yes or no? features and painful symptoms, Lucia Lazzeri (Italy) - Resad Pasic (USA) - A study of the histopathological changes - Hervé Fernandez (France) within ectopic endometrial tissue, in subjects 12:30 SPONSORED BY with known pelvic endometriosis following treatment Uterine fibroids 14:00 and infertility with ulipristal acetate, Paul D. Simpson (United Kingdom) - Combined treatment of gestrinone with histone SUMMIT 1 Chairs: Francisco Carmona (Spain) deacetylase inhibitors for the treatment of deep & Edgardo Somigliana (Italy) - Uterine fibroid and endometrial receptivity: the molecular endometriosis-associated pain, Hugo Maia Jr. (Brazil) - Endometriosis and the human microbiome, basis for reduced endometrial receptivity in uterine fibroids and polyps, Jim Tsaltas (Australia) Giuliano Borrelli (Brazil) - Activated platelets induce hypoxia-inducible - Uterine contraction: possibility of tailored medicine factor-1alpha (HIF-1 ) expression through TGF- 1 for intramural fibroids, Yutaka Osuga (Japan) β β - Uterine fibroids and infertility: where is the clinical in human endometrial stromal cells, Qiuming Qi (China) evidence? Paola Piomboni (Italy) ROOM 331 Free communications 12 - ART and uterine fibroids, Gamal Serour (Egypt) Chairs: Pietro Santulli (France) & Lip Kee Yap (Singapore) 14:00 - Genitourinary involvement in deep infiltrating Awards SUMMIT 1 & Closing ceremony SPONSORED BY endometriosis, Olga Bougie (Canada) - Urological deep infiltrating endometriosis patient 15:00 Patients characteristics : from ureter to bladder, 17:00 session Wirawan Florencia (Indonesia) ROOM - The more effective incision method for extracting large 331/332 uterine fibroids in laparoscopic myomectomy, Ryo Nimura (Japan) 13 PARTNERS

DIAMOND SPONSORS

GOLD SPONSORS

SILVER SPONSORS

BRONZE SPONSOR