MRGPRX4 Is a Novel Bile Acid Receptor in Cholestatic Itch Huasheng Yu1,2,3, Tianjun Zhao1,2,3, Simin Liu1, Qinxue Wu4, Omar
bioRxiv preprint doi: https://doi.org/10.1101/633446; this version posted May 9, 2019. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under aCC-BY-NC-ND 4.0 International license. 1 MRGPRX4 is a novel bile acid receptor in cholestatic itch 2 Huasheng Yu1,2,3, Tianjun Zhao1,2,3, Simin Liu1, Qinxue Wu4, Omar Johnson4, Zhaofa 3 Wu1,2, Zihao Zhuang1, Yaocheng Shi5, Renxi He1,2, Yong Yang6, Jianjun Sun7, 4 Xiaoqun Wang8, Haifeng Xu9, Zheng Zeng10, Xiaoguang Lei3,5, Wenqin Luo4*, Yulong 5 Li1,2,3* 6 7 1State Key Laboratory of Membrane Biology, Peking University School of Life 8 Sciences, Beijing 100871, China 9 2PKU-IDG/McGovern Institute for Brain Research, Beijing 100871, China 10 3Peking-Tsinghua Center for Life Sciences, Beijing 100871, China 11 4Department of Neuroscience, Perelman School of Medicine, University of 12 Pennsylvania, Philadelphia, PA 19104, USA 13 5Department of Chemical Biology, College of Chemistry and Molecular Engineering, 14 Peking University, Beijing 100871, China 15 6Department of Dermatology, Peking University First Hospital, Beijing Key Laboratory 16 of Molecular Diagnosis on Dermatoses, Beijing 100034, China 17 7Department of Neurosurgery, Peking University Third Hospital, Peking University, 18 Beijing, 100191, China 19 8State Key Laboratory of Brain and Cognitive Science, CAS Center for Excellence in 20 Brain Science and Intelligence Technology (Shanghai), Institute of Biophysics, 21 Chinese Academy of Sciences, Beijing, 100101, China 22 9Department of Liver Surgery, Peking Union Medical College Hospital, Chinese bioRxiv preprint doi: https://doi.org/10.1101/633446; this version posted May 9, 2019.
[Show full text]