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5. the Lives of Two Pioneering Medical Chemists.Indd
The West of England Medical Journal Vol 116 No 4 Article 2 Bristol Medico-Historical Society Proceedings The Lives of Two Pioneering Medical-Chemists in Bristol Thomas Beddoes (1760-1808) and William Herapath (1796-1868) Brian Vincent School of Chemistry, University of Bristol, Bristol, BS8 1TS. Presented at the meeting on Dec 12th 2016 ABSTRACT From the second half of the 18th century onwards the new science of chemistry took root and applications were heralded in many medical-related fields, e.g. cures for diseases such as TB, the prevention of epidemics like cholera, the application of anaesthetics and the detection of poisons in forensics. Two pioneering chemists who worked in the city were Thomas Beddoes, who founded the Pneumatic Institution in Hotwells in 1793, and William Herapath who was the first professor of chemistry and toxicology at the Bristol Medical School, located near the Infirmary, which opened in 1828. As well as their major contributions to medical-chemistry, both men played important roles in the political life of the city. INTRODUCTION The second half of the 18th century saw chemistry emerge as a fledgling science. Up till then there was little understanding of the true nature of matter. The 1 The West of England Medical Journal Vol 116 No 4 Article 2 Bristol Medico-Historical Society Proceedings classical Greek idea that matter consisted of four basic elements (earth, fire, water and air) still held sway, as did the practice of alchemy: the search for the “elixir of life” and for the “philosophers’ stone” which would turn base metals into gold. -
1 Travis Chi Wing Lau Dissertation Abstract Prophylactic Fictions
Travis Chi Wing Lau Dissertation Abstract Prophylactic Fictions: Immunity and Biosecurity traces a prehistory for inoculation insecurity, a term I use to capture the fluid responses in literary and scientific writings to the development of inoculation as a preventative health practice. The concept of immunity, from its Roman legal origins as immunitas (i.e. exemption from civic duty), has always been a political issue regarding the role of the citizen in relation to the state. However, throughout the eighteenth and nineteenth centuries, immunity became naturalized through developments in medical theory and practice, which increasingly insisted upon the relationship among healthy nations, healthy constitutions, and healthy citizens. Arguing that the “symbolic and material linchpin” of Western modernity is a paradigm of immunity, Roberto Esposito marks in this period a pivotal shift for immunity from a passive to an active condition. Resistance to or “security” from disease became achievable by the lancet. Yet the deliberate introduction of infectious matter into the body was by no means innocuous in the eyes of the public. The stakes of what matter and how that matter was administered became, for many, a matter of life and death. Prophylactic Fictions tracks how inoculation, alongside other preventative health projects, found its way into the burgeoning apparatuses of population security aimed at mitigating and preventing mounting risks to citizens’ wellbeing. Despite the historical interrelationship between inoculation and security, only recently has scholarship in security studies and in philosophy’s “immunological turn” begun to flesh out the implications of that interrelationship. Missing from this primarily presentist scholarship are perspectives from the history of medicine and literary studies. -
Humphry Davy, Nitrous Oxide, the Pneumatic Institution, and the Royal Institution
Am J Physiol Lung Cell Mol Physiol 307: L661–L667, 2014. First published August 29, 2014; doi:10.1152/ajplung.00206.2014. Perspectives Humphry Davy, nitrous oxide, the Pneumatic Institution, and the Royal Institution John B. West Department of Medicine, University of California San Diego, La Jolla, California Submitted 23 July 2014; accepted in final form 18 August 2014 West JB. Humphry Davy, nitrous oxide, the Pneumatic Institu- magnesium, boron, and barium. Davy is also well known as the tion, and the Royal Institution. Am J Physiol Lung Cell Mol Phy- person responsible for developing the miner’s safety lamp. siol 307: L661–L667, 2014. First published August 29, 2014; There is an extensive literature on Davy. A readable intro- doi:10.1152/ajplung.00206.2014.—Humphry Davy (1778–1829) has an duction is Hartley’s (8). The biography by Knight (10) is more interesting place in the history of respiratory gases because the detailed and contains useful citations to primary sources. Tre- Pneumatic Institution in which he did much of his early work signaled neer (17) wrote another biography with an emphasis on Davy’s the end of an era of discovery. The previous 40 years had seen relations with other people including his wife and also Faraday. essentially all of the important respiratory gases described, and the Partington (12) is authoritative on his chemical research. Institution was formed to exploit their possible value in medical Davy’s collected works are available (6). treatment. Davy himself is well known for producing nitrous oxide and demonstrating that its inhalation could cause euphoria and height- Early Years ened imagination. -
The Beast Within: the Imperial Legacy of Vaccination in History and Literature
The Beast Within: The Imperial Legacy of Vaccination in History and Literature Debbie Lee Washington State University Tim Fulford Nottingham Trent University Jenner and the Origins of Vaccination’s Empire Hands tell a lot about people. The hand pictured here (Figure 1), an engrav- ing published in Britain in 1798, seems especially telling. It appears today, just as it must have to viewers of that era, strangely embodied, as if one could tell from its graceful arch, its refined whiteness, and its seeming gesture, who it might belong to. In fact, to the British of the early nineteenth century, it would have been clear from the three marks, as round as little globes, that this was not the hand of a gentlewoman but that of a dairy maid who had been infected with the common disease called ‘cowpox’. This hand, in particular, belonged to Sarah Nelmes and, paradoxically, it carried both the blessing of world health and the curse of Western imperialism in its elegant grasp. Figure 1 The hand of Sarah Nelmes, printed in Edward Jenner’s 1798 An Inquiry into the Causes and Effects of the Variolae Vaccinae. By permission of the Jenner Museum, Berkeley. 1 Literature & History third series 9/1 Nelmes’s hand appeared in Edward Jenner’s 1798 treatise An Inquiry into The Causes and Effects of the Variolae Vaccinae, A Disease Discovered in Some of the Western Counties of England … and known by the name of The Cow Pox.1 Jenner’s Inquiry was beautiful in its simplicity. It came from the bodies of those who worked in the English countryside. -
Dr Thomas Beddoes and James Watt: Pneumatic Institute
Medical History, 1986, 30: 276-302. DR THOMAS BEDDOES AND JAMES WATT: PREPARATORY WORK 1794-96 FOR THE BRISTOL PNEUMATIC INSTITUTE by DOROTHY A. STANSFIELD* AND RONALD G. STANSFIELDt PART I. BEDDOES' THEORIES, HIS WORK, THE INTERVENTION OF JAMES WATT In 1793, Dr Thomas Beddoes moved from Oxford, where he had won a considerable reputation as Chemical Reader, and established himself as a physician in Bristol. This was not an easy period for him, since he had a reputation for being an active sympathizer with the French Revolution and was known to the Home Office as the author of anti-government pamphlets sufficiently subversive to merit investigation. Not surprisingly, the University authorities, on the advice ofthe Home Office, had felt obliged to abandon a proposal that Beddoes should remain in Oxford while a University Chair of Chemistry was established.' Beddoes had been prepared to postpone plans ofhis own, but in the changed circumstances he returned to the purpose which had originally led him to decide to leave Oxford. This was to test in practice the possibility that gases might be found useful in the treatment of, in particular, pulmonary tuberculosis, and he arrived in Bristol with a clear plan in mind. He settled near to the Hotwells, where many sufferers from tuberculosis were gathered in the hope ofa cure, and built up a practice that would support him, for he had undertaken not to derive any income from his work for the pneumatic project. In the same year (1793), he published three papers,2'3 which explained the scientific thinking behind pneumatic medicine, showed what had already been attempted, and endeavoured to allay fears that his experiments were dangerous and irresponsible. -
Gas and Poetry: Humphry Davy in Bristol, 1798-1801
1 17 September 2019 Gas and Poetry: Humphry Davy in Bristol, 1798-1801 Frank A.J.L. James University College London* http://orcid.org/0000-0002-0499-9291 This paper is a contribution, historically grounded, to current discussions about how best to understand the relations of science and literature as cultural and social practices. It examines, in some detail, Humphry Davy’s activities during the two and a half years, from the autumn of 1798 to the spring of 1801, that he worked at Thomas Beddoes’s Medical Pneumatic Institution in Bristol. The loose and ever- changing circle of creative individuals who formed around Beddoes and his Institution involved a formidable array of savants including members of the Watt and Wedgwood families as well as Romantics such as Southey, Coleridge and Wordsworth. The micro-chronological approach adopted here reveals the importance of print culture and sociability in the production of texts and knowledge, as well as the striking number and variety of projects proposed by the circle that never came to fruition. Nevertheless, those successful projects, such as Davy’s work on nitrous oxide and the second edition of Wordsworth’s Lyrical Ballads, contributed to making this period one of the key moments in English cultural history. Keywords: Humphry Davy, Thomas Beddoes, Robert Southey, Samuel Taylor Coleridge, William Wordsworth, Bristol, the Medical Pneumatic Institution, Jacobin Politics, Nitrous * Department of Science and Technology Studies, University College London, Gower Street, London, WC1E 6BT, England; The Royal Institution, 21 Albemarle Street, London, W1S 4BS, England. E-mail: [email protected]. An earlier version of this paper was presented at the “Robert Southey and Romantic-era literature, culture and science: 1797, 1817, a Bicentennial Conference” held during April 2016 in Clifton. -
Doctors, the State, and the Ethics of Political Medical Practice Dorothy Porter, Phd
Virtual Mentor American Medical Association Journal of Ethics December 2007, Volume 9, Number 12: 832-837. MEDICINE AND SOCIETY Doctors, the State, and the Ethics of Political Medical Practice Dorothy Porter, PhD The social institutions of medicine and the state have a complex history of interaction in which doctors have been the originators of political ideals, goals, and social change but have equally found themselves instruments of political authority. Here I briefly chart some significant moments in what might be termed the political history of medicine, looking at doctors both as actors structuring and as agents implementing the operations of modern democratic states. Idealists and Actors in Political and Social Change The 18th-century English physician and political radical Thomas Beddoes considered medicine and social morality to be inherently bound in an ethics of corporal existence. Without accurate ideas of the causes that affect the personal condition of mankind, how is it possible to conceive any progress in genuine morality? And will not every addition to this branch of knowledge necessarily tend to purify morals—that is, to introduce into the social compact covenants more beneficial to the parties? Physiology—or more strictly biology—by which I mean the doctrine of the living system in all its states, appears to be the foundation of ethics and pneumatology [1]. Beddoes’ link between the needs of the body natural and the social morality of the body politic has underwritten a moral justification for medicine’s playing a role in constructing modern democratic states since the 19th century [2]. In 1848, political reformer, medical doctor, and founder of cellular pathology, Rudolph Virchow, articulated that the moral goal of the political role of medicine was to become an active agent in eliminating social inequality [3]. -
Thomas Beddoes M.D. 1760-1808 Chemists and Chemistry
THOMAS BEDDOES M.D. 1760-1808 CHEMISTS AND CHEMISTRY A series of books devoted to the examination of the history and development of chemistry from its early emergence as a separate discipline to the present day. The series will describe the personalities, processes, theoretical and iechnical advances which have shaped our current understanding of chemical science. DOROTHY A. STANSFIELD THOMAS BEDDOES M.D. 1760-1808 Chemist, Physician, Democrat D. REIDEL PUBLISHING COMPANY A MEMBER OF THE KLUWER ACADEMIC PUBLISHERS GROUP DORDRECHT/BOSTON/LANCASTER Library of Congress Cataloging in Publication Data Stansfield, Dorothy A., 1914- Thomas Beddoes, M.D., 1760-1808. (Chemists and chemistry) Bibliography: p. Includes indexes. 1. Beddoes, Thomas, 1760-1808. 2. Chemists - England Biography. 3. Physicians - England - Biography. I. Title. II. Series. QD22.B263S83 1984 540'.92'4 [BI 84-8421 ISBN-13: 978-94-009-6305-4 e-ISBN-13:978-94-009-6303-0 DOl: 10.1007/978-94-009-6303-0 Published by D. Reidel Publishing Company. P.O. Box 17, 3300 AA Dordrecht, Holland. Sold and distributed in the U.S.A. and Canada by Kluwer Academic Publishers, 190 Old Derby Street, Hingham, MA 02043, U.S.A. In all other countries, sold and distributed by Kluwer Academic Publishers Group, P.O. Box 322, 3300 AH Dordrecht, Holland. All Rights Reserved. © 1984 by D. Reidel Publishing Company. Softcover reprint of the hardcover 1st edition 1984 No part of the material protected by this copyright notice may be reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording or by any information storage and retrieval system, without written permission from the copyright owner. -
Historical Group Occasional Paper 8
‘the first example … of an extensive scheme of pure scientific medical investigation’: Thomas Beddoes and the Medical Pneumatic Institution in Bristol, 1794 to 1799 Frank A.J.L. James Department of Science and Technology Studies, University College London, Gower Street, London, WC1E 6BT, England Royal Institution, 21 Albemarle Street, London, W1S 4BS, England [email protected] The Eighth Wheeler Lecture Royal Institution, 12 October 2015 RSCHG Occasional Paper No. 8, published November 2016 ISBN: 2050-0424 Series Editor: Dr Anna Simmons ORCID identification number (http://orcid.org/0000-0002-0499-9291) Acknowledgements I thank the following archives for permission to study manuscripts and other documents in their collections: Library of Birmingham (LoB), Cornwall Record Office (CRO), Wedgwood Museum (WM), The National Archives (TNA), Bristol Record Office (BRO), British Library (BL), National Library of Ireland (NLI), Bedfordshire and Luton Archive Service (BALAS), the Royal Institution (RI), Natural History Museum (NHM), the Royal Society of London, the Linnean Society, Bristol Central Library, McGill University, Chatsworth, Lambton Park and the Bodleian Library. Letters written by Humphry Davy are freely available on-line at <www.davy-letters.org.uk> as part of the project to publish them by the end of the decade. In the meantime, this paper cites their archival or printed locations. I thank the Research Group of the STS Department at University College London for many valuable comments on an earlier draft. Note to Readers Because of the tendency of the Wedgwood, Watt and Boulton families to use the same forenames in succeeding generations, both the fore and surnames of correspondents are given consistently in the notes. -
The Subversive Humphry Davy: Aristocracy and Establishing Chemical Research Laboratories in Late Eighteenth- and Early Nineteenth-Century England
View metadata, citation and similar papers at core.ac.uk brought to you by CORE provided by UCL Discovery The Subversive Humphry Davy: Aristocracy and Establishing Chemical Research Laboratories in Late Eighteenth- and Early Nineteenth-Century England Frank A.J.L. James* Introduction As other papers in this volume testify, chemistry, in all its multifarious guises throughout Europe, could be undertaken within a wide range of institutional, organisational and physical settings. This essay discusses the beginnings in England at the end of the eighteenth century of one type of setting, namely institutional laboratories funded by subscription that were either envisioned or came to be devoted to chemical research. Such laboratories required a number of material things before they could start to produce scientific knowledge: a building, building services (heating, lighting, water etc.) and apparatus. Furthermore appropriately trained staff including researchers, laboratory assistants and servants, also needed to be found. Less tangibly, it was important to have available retrievable recording methods and some access to disseminating the knowledge produced. These components did not appear of their own volition, but required substantial financial support, to be organised and governed, all through human agency. Even today none of this is straightforward, but when no appropriate models were available that could be followed to achieve the desired aims, the difficulties became manifold. Inevitably under such circumstances a strong tendency existed to underdefine and underspecify what a laboratory required, particularly in terms of management, and to start with the familiar. That all left ample scope for unintended consequences, the idiosyncrasies of individual agency and the subversion of original aims. -
Industrial Revolution, Series III, Parts 1 to 3
Industrial Revolution, Series III, Parts 1 to 3 INDUSTRIAL REVOLUTION: A DOCUMENTARY HISTORY Series Three: The Papers of James Watt and his Family formerly held at Doldowlod House, now at Birmingham Central Library Part 1: Correspondence, Papers & Business Records, 1687-1819 Part 2: Correspondence, Papers & Business Records, 1736-1848 Part 3: Correspondence, Papers & Business Records, 1736-1848 Contents listing INTRODUCTION BY NICHOLAS KINGSLEY PUBLISHER'S NOTE TECHNICAL NOTE CONTENTS OF REELS - PART 1 DETAILED LISTING - PART 1 CONTENTS OF REELS - PART 2 DETAILS LISTING - PART 2 CONTENTS OF REELS - PART 3 DETAILED LISTING - PART 3 LETTER BOOK INDEX NOTES ON INDIVIDUALS INDEX OF NAMED INDIVIDUALS CONSPECTUS OF BUNDLE NUMBERS AND REELS NUMBERS Industrial Revolution, Series III, Parts 1 to 3 Introduction by Nicholas Kingsley, to the Papers of James Watt and his family These documents were purchased from Lord Gibson-Watt, Doldowlod House,Llandundod Wells, Powys, in June 1994, with the assistance of the National Heritage Memorial Fund, Victoria and Albert Purchase Grant Fund and may other donors. They are now housed in the Archives Division of Birmingham Central Library with the shelfmark JWP (ACC 94/69) James Watt James Watt (1736-1819), surveyor, engineer, mathematical and musical instrument maker, chemist and inventor, is famous for his invention in 1765 of the separate condenser, the crucial refinement of Thomas Newcomen's steam engine. The steam engine as improved by Watt was probably the most important technological advance of the industrial revolution; with the fuel economies of the separate condenser, steam engines could operate anywhere. Later improvements included a new coupling so that the engine could work in both directions, rotative motion, and a governor for safety. -
Dr Thomas Beddoes and James Watt: Preparatory Work 1794-96 for the Bristol Pneumatic Institute
Medical History, 1986, 30: 276-302. DR THOMAS BEDDOES AND JAMES WATT: PREPARATORY WORK 1794-96 FOR THE BRISTOL PNEUMATIC INSTITUTE by DOROTHY A. STANSFIELD* AND RONALD G. STANSFIELDt PART I. BEDDOES' THEORIES, HIS WORK, THE INTERVENTION OF JAMES WATT In 1793, Dr Thomas Beddoes moved from Oxford, where he had won a considerable reputation as Chemical Reader, and established himself as a physician in Bristol. This was not an easy period for him, since he had a reputation for being an active sympathizer with the French Revolution and was known to the Home Office as the author of anti-government pamphlets sufficiently subversive to merit investigation. Not surprisingly, the University authorities, on the advice ofthe Home Office, had felt obliged to abandon a proposal that Beddoes should remain in Oxford while a University Chair of Chemistry was established.' Beddoes had been prepared to postpone plans ofhis own, but in the changed circumstances he returned to the purpose which had originally led him to decide to leave Oxford. This was to test in practice the possibility that gases might be found useful in the treatment of, in particular, pulmonary tuberculosis, and he arrived in Bristol with a clear plan in mind. He settled near to the Hotwells, where many sufferers from tuberculosis were gathered in the hope ofa cure, and built up a practice that would support him, for he had undertaken not to derive any income from his work for the pneumatic project. In the same year (1793), he published three papers,2'3 which explained the scientific thinking behind pneumatic medicine, showed what had already been attempted, and endeavoured to allay fears that his experiments were dangerous and irresponsible.