An Epidemiologic Analysis of Co-Occurring Alcohol and Tobacco Use and Disorders

Total Page:16

File Type:pdf, Size:1020Kb

An Epidemiologic Analysis of Co-Occurring Alcohol and Tobacco Use and Disorders An Epidemiologic Analysis of Co-Occurring Alcohol and Tobacco Use and Disorders Findings From the National Epidemiologic Survey on Alcohol and Related Conditions Daniel E. Falk, Ph.D.; Hsiao-ye Yi, Ph.D.; and Susanne Hiller-Sturmhöfel, Ph.D. The 2001–2002 National Epidemiologic Survey on Alcohol and Related Conditions (NESARC) sought to determine the prevalence of drinking, smoking, and associated disorders in the general population. This survey, which includes a large representative sample of the adult population of the United States, found that drinking rates were highest among young adults and declined with increasing age. Rates of smoking and co-use of alcohol and tobacco were highest among the youngest respondents and declined thereafter. Similar patterns existed for the presence of alcohol use disorders (AUDs), nicotine dependence, and comorbidity between AUDs and nicotine dependence. Among ethnic/racial groups evaluated, Whites were most likely to drink and Native Americans/Alaskan Natives were most likely to smoke and to have an AUD, nicotine dependence, or comorbid AUD and nicotine dependence. Finally, the rates of tobacco use, daily tobacco use, and nicotine dependence increased with increasing levels of alcohol consumption and the presence of an AUD. These findings have important implications for the development of prevention and intervention approaches. KEY WORDS: Age differences; epidemiology; alcohol and other drug use disorders (AODD); racial differences; tobacco; nicotine; comorbidity; ethnic differences; gender differences umerous studies have demon- and society, it is important to understand the treatment outcome for dependence strated that excessive alcohol the mechanisms contributing to the use on the other substance. For example, Nconsumption and tobacco use and abuse of both substances. Many studies have begun to address the fol­ are independently associated with a studies into these mechanisms have lowing questions: Are alcohol-dependent plethora of health-related, social, and identified brain molecules, such as neu- patients who are also nicotine depen­ economic adverse consequences for the rotransmitters and nicotinic receptors, dent less likely to have successful alco­ consumers of these legal substances as that interact with alcohol and/or nico- holism treatment outcomes than those well as for society at large (Centers for tine and which mediate the effects of Disease Control and Prevention [CDC] these substances on the brain. Similar 2004, 2005a). Some of these detrimen- analyses also have identified mechanisms DANIEL E. FALK, PH.D., is a research tal effects can be exacerbated in people that mediate sensitivity to alcohol and/ analyst and HSIAO-YE YI, PH.D., is a who use and abuse both substances. For or nicotine, as well as the rewarding senior research analyst with the Alcohol example, the risk of certain cancers is properties of the two drugs. (For more Epidemiologic Data System of the greater for people who drink and smoke information on these mechanisms, see National Institute on Alcohol Abuse and than for people who use only one of the articles by Funk and colleagues, Alcoholism (NIAAA), which is operated these substances (National Institute on Davis and de Fiebre, and Grucza and by CSR, Incorporated, Arlington, Virginia. Alcohol Abuse and Alcoholism [NIAAA] Bierut in this issue.) 1998a). To prevent the harmful inter- Another large area of research is con- SUSANNE HILLER-STURMHÖFEL, PH.D., action of alcohol and tobacco use and cerned with how the use of or depen- is senior science editor for Alcohol ameliorate its impact on the individual dence on one of these substances affects Research & Health. 162 Alcohol Research & Health Co-Occurring Alcohol and Tobacco Use Disorders patients who are not nicotine dependent? • DiFranza and Guerrera (1990) is based on a comprehensive definition Should both dependencies be treated at found that 83 percent of alcoholics of tobacco use including all tobacco the same time or consecutively? And are were smokers, compared with 34 modalities, with all prevalence estimates special treatment approaches needed for percent of nonalcoholics. presented by gender, race/ethnicity, and patients who are dependent on both age. In addition, the present study rather than just one substance? This • Bobo and Husten (2000) showed expands upon the work of Anthony research already has yielded valuable that 37 percent of adults who were and Echeagaray-Wagner (2000) by insights. (For more information, see the classified as current drinkers were analyzing how tobacco use and nicotine articles by Foulds and colleagues, Gulliver also current smokers, compared dependence vary with levels of alcohol and colleagues, Ziedonis and colleagues, with 13 percent of abstainers. consumption and types of alcohol use and Kodl and colleagues in this issue.) disorders (AUDs). Although all of these avenues of • Other analyses indicated that smoking research are of the utmost importance, it rates and the number of cigarettes smoked increase with increasing is equally critical to obtain a solid under­ Methods alcohol consumption (e.g., Friedman standing of the scope of the problem. et al. 1991). Thus, it is important to know the rates Data of alcohol and tobacco use and co-use in Although data such as these strongly the general population and whether certain point to an association between drinking The present study is based on data from demographic subgroups are particularly and smoking, the existing studies often the first wave of the NIAAA-sponsored at risk of using both alcohol and tobacco have characteristics that, while making NESARC, which was conducted in or being dependent on both substances. them useful for addressing specific 2001–2002. NESARC is among the Studies of this nature are rare in the research questions, limit their generaliz­ largest nationally representative comor­ literature. In a previous issue of Alcohol ability to the general population. These bidity surveys ever conducted and Research & Health, Anthony and characteristics include the use of treatment includes extensive questions on alcohol Echeagaray-Wagner (2000) presented samples, local community samples, or and tobacco (as well as other substance) an epidemiologic analysis of alcohol and special subpopulation samples rather use and related disorders. The NESARC tobacco use and co-use using national than nationally representative samples. sample includes 43,093 respondents data collected before 1997. This analysis Moreover, most comorbidity studies ages 18 and older, representing the found that the prevalence of co-occurring focused on smoking or cigarette smok­ civilian, noninstitutionalized adult alcohol and tobacco use and disorders ing as the measure of tobacco use (e.g., population of the United States, includ­ was lowest among young adolescents, Dawson 2000; Anthony and Echeagaray- ing residents of all 50 States and the peaked among young adults, and Wagner 2000; Friedman et al. 1991), District of Columbia. Military personnel declined thereafter. The peak rate of ignoring other modalities of tobacco living off base and persons living in alcohol and tobacco co-use among young use (e.g., the use of snuff and chewing noninstitutionalized group-quarter adults ranged from 35 to 45 percent, tobacco). In addition, many of the housing, such as boarding houses, shelters, and dormitories, also were included (Grant and the peak rate of co-dependence was existing studies were based on surveys et al. 2003). The sampling frames for approximately 10 percent. conducted in the 1980s and have used housing units and group-quarter units In addition to determining the diagnostic criteria that are no longer current. Particularly with the preva­ were derived from the Census 2000/ prevalence of co-occurring alcohol and 2001 Supplementary Survey and the tobacco use and disorders in the general lence of tobacco use declining dramati­ cally in the United States in recent Census 2000 Group Quarters Inventory, population and for certain demographic decades (Marks et al. 1997; CDC 2005b), respectively. NESARC oversampled subgroups, it is important to understand epidemiological studies based on current Blacks, Hispanics, and young adults how rates of tobacco use and nicotine national data are needed to provide (ages 18–24) to allow for more reliable dependence vary among people with updated estimates of alcohol and tobacco estimates of these groups. Data were col­ different characteristics of alcohol con­ co-use in the general population. lected via face-to-face, computer-assisted sumption. Over the last 20 years or more, This article addresses these issues interviews in household settings. From accumulating evidence has indeed by updating the findings presented by each household, one adult was selected pointed to a dose-response relationship Anthony and Echeagaray-Wagner for interview. The overall response rate between alcohol and tobacco use: (2000) using data from the 2001–2002 for NESARC was 81 percent. National Epidemiologic Survey on • Dawson (2000) reported that peo­ Alcohol and Related Conditions Measures ple who abuse or are dependent (NESARC). The main objective is to on alcohol are more likely to use present data on the prevalence and Alcohol Measures. All alcohol mea­ tobacco and are heavier users than pattern of alcohol and tobacco use and sures reflect consumption and diagnos­ people who abstain from alcohol. co-use in the United States. This analysis tic status during the past year (i.e., the Vol. 29, No. 3, 2006 163 12 months
Recommended publications
  • Smoking Cessation Treatment at Substance Abuse Rehabilitation Programs
    SMOKING CEssATION TREATMENT AT SUBSTANCE ABUSE REHABILITATION PROGRAMS Malcolm S. Reid, PhD, New York University School of Medicine, Department of Psychiatry; Jeff Sel- zer, MD, North Shore Long Island Jewish Healthcare System; John Rotrosen, MD, New York University School of Medicine, Department of Psychiatry Cigarette smoking is common among persons with drug and alcohol n Nicotine is a highly use disorders, with prevalence rates of 80-90% among patients in sub- addictive substance stance use disorder treatment programs. Such concurrent smoking may that meets all of produce adverse behavioral and medical problems, and is associated the criteria for drug with greater levels of substance use disorder. dependence. CBehavioral studies indicate that the act of cigarette smoking serves as a cue for drug and alcohol craving, and the active ingredient of cigarettes, nicotine, serves as a primer for drug and alcohol abuse (Sees and Clarke, 1993; Reid et al., 1998). More critically, longitudinal studies have found tobacco use to be the number one cause of preventable death in the United States, and also the single highest contributor to mortality in patients treated for alcoholism (Hurt et al., 1996). Nicotine is a highly addictive substance that meets all of the criteria for drug dependence, and cigarette smoking is an especially effective method for the delivery of nicotine, producing peak brain levels within 15-20 seconds. This rapid drug delivery is one of a number of common properties that cigarette smok- ing shares with hazardous drug and alcohol use, such as the ability to activate the dopamine system in the reward circuitry of the brain.
    [Show full text]
  • Alcohol, Tobacco, and Prescription Drugs: the Relationship with Illicit Drugs in the Treatment of Substance Users
    Macquarie University ResearchOnline This is the author version of an article published as: Teesson, M., Farrugia, P., Mills, K., Hall, W., & Baillie, A. (2012). Alcohol, tobacco, and prescription drugs: The relationship with illicit drugs in the treatment of substance users. Substance use & misuse, Vol. 47, Issue 8-9, p. 963-971. Access to the published version: http://doi.org/10.3109/10826084.2012.663283 Copyright: Copyright the Publisher 2012. Version archived for private and non- commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher. Comorbidity 1 Alcohol, tobacco and prescription drugs: The relationship with illicit drugs in the treatment of substance users. Maree Teesson, Philippa Farrugia, Katherine Mills 1 Wayne Hall2, Andrew Baillie3. 1. National Drug and Alcohol Research Centre, University of New South Wales, Sydney, New South Wales 2052 Australia, 2. University of Queensland Centre for Clinical Research, 3. Centre for Emotional Health, Department of Psychology, Macquarie University. * Corresponding author: Maree Teesson National Drug and Alcohol Research Centre University of New South Wales, Sydney New South Wales 2052 Australia Tel: +61 2 9385 0333; fax: +61 2 9385 0222; email: [email protected] Abstract Alcohol, tobacco, prescription drug and illicit drug use frequently co-occur. This paper reviews the extent of this co-occurrence in both general population samples and clinical samples, and its impact on treatment outcome. We argue that the research base for understanding comorbidity between tobacco, alcohol, prescription and illicit drugs needs to be broadened. We specifically advocate for: 1) more epidemiological studies of relationships between alcohol, tobacco and other illicit drug use; and 2) increased research on treatment options that address the problematic use of all of these drugs.
    [Show full text]
  • Concurrent Alcohol and Tobacco Dependence
    Concurrent Alcohol and Tobacco Dependence Mechanisms and Treatment David J. Drobes, Ph.D. People who drink alcohol often also smoke and vice versa. Several mechanisms may contribute to concurrent alcohol and tobacco use. These mechanisms include genes that are involved in regulating certain brain chemical systems; neurobiological mechanisms, such as cross-tolerance and cross-sensitization to both drugs; conditioning mechanisms, in which cravings for alcohol or nicotine are elicited by certain environmental cues; and psychosocial factors (e.g., personality characteristics and coexisting psychiatric disorders). Treatment outcomes for patients addicted to both alcohol and nicotine are generally worse than for people addicted to only one drug, and many treatment providers do not promote smoking cessation during alcoholism treatment. Recent findings suggest, however, that concurrent treatment for both addictions may improve treatment outcomes. KEY WORDS: comorbidity; AODD (alcohol and other drug dependence); alcoholic beverage; tobacco in any form; nicotine; smoking; genetic linkage; cross-tolerance; AOD (alcohol and other drug) sensitivity; neurotransmitters; brain reward pathway; cue reactivity; social AODU (AOD use); cessation of AODU; treatment outcome; combined modality therapy; literature review lcohol consumption and tobacco ers who are dependent on nicotine Department of Health and Human use are closely linked behaviors. have a 2.7 times greater risk of becoming Services 1989). The concurrent use of A Thus, not only are people who alcohol dependent than nonsmokers both drugs by pregnant women can drink alcohol more likely to smoke (and (e.g., Breslau 1995). Finally, although also result in more severe prenatal dam- vice versa) but also people who drink the smoking rate in the general popula­ age and neurocognitive deficits in their larger amounts of alcohol tend to smoke tion has gradually declined over the offspring than use of either drug alone more cigarettes.
    [Show full text]
  • Barriers and Solutions to Addressing Tobacco Dependence in Addiction Treatment Programs
    Barriers and Solutions to Addressing Tobacco Dependence in Addiction Treatment Programs Douglas M. Ziedonis, M.D., M.P.H.; Joseph Guydish, Ph.D., M.P.H.; Jill Williams, M.D.; Marc Steinberg, Ph.D.; and Jonathan Foulds, Ph.D. Despite the high prevalence of tobacco use among people with substance use disorders, tobacco dependence is often overlooked in addiction treatment programs. Several studies and a meta-analytic review have concluded that patients who receive tobacco dependence treatment during addiction treatment have better overall substance abuse treatment outcomes compared with those who do not. Barriers that contribute to the lack of attention given to this important problem include staff attitudes about and use of tobacco, lack of adequate staff training to address tobacco use, unfounded fears among treatment staff and administration regarding tobacco policies, and limited tobacco dependence treatment resources. Specific clinical-, program-, and system-level changes are recommended to fully address the problem of tobacco use among alcohol and other drug abuse patients. KEY WORDS: Alcohol and tobacco; alcohol, tobacco, and other drug (ATOD) use, abuse, dependence; addiction care; tobacco dependence; smoking; secondhand smoke; nicotine; nicotine replacement; tobacco dependence screening; tobacco dependence treatment; treatment facility-based prevention; co-treatment; treatment issues; treatment barriers; treatment provider characteristics; treatment staff; staff training; AODD counselor; client counselor interaction; smoking cessation; Tobacco Dependence Program at the University of Medicine and Dentistry of New Jersey obacco dependence is one of to the other. The common genetic vul­ stance use was considered a potential the most common substance use nerability may be located on chromo­ trigger for the primary addiction.
    [Show full text]
  • Evidence-Based Guidelines for the Pharmacological Management of Substance Abuse, Harmful Use, Addictio
    444324 JOP0010.1177/0269881112444324Lingford-Hughes et al.Journal of Psychopharmacology 2012 BAP Guidelines BAP updated guidelines: evidence-based guidelines for the pharmacological management of substance abuse, Journal of Psychopharmacology 0(0) 1 –54 harmful use, addiction and comorbidity: © The Author(s) 2012 Reprints and permission: sagepub.co.uk/journalsPermissions.nav recommendations from BAP DOI: 10.1177/0269881112444324 jop.sagepub.com AR Lingford-Hughes1, S Welch2, L Peters3 and DJ Nutt 1 With expert reviewers (in alphabetical order): Ball D, Buntwal N, Chick J, Crome I, Daly C, Dar K, Day E, Duka T, Finch E, Law F, Marshall EJ, Munafo M, Myles J, Porter S, Raistrick D, Reed LJ, Reid A, Sell L, Sinclair J, Tyrer P, West R, Williams T, Winstock A Abstract The British Association for Psychopharmacology guidelines for the treatment of substance abuse, harmful use, addiction and comorbidity with psychiatric disorders primarily focus on their pharmacological management. They are based explicitly on the available evidence and presented as recommendations to aid clinical decision making for practitioners alongside a detailed review of the evidence. A consensus meeting, involving experts in the treatment of these disorders, reviewed key areas and considered the strength of the evidence and clinical implications. The guidelines were drawn up after feedback from participants. The guidelines primarily cover the pharmacological management of withdrawal, short- and long-term substitution, maintenance of abstinence and prevention of complications, where appropriate, for substance abuse or harmful use or addiction as well management in pregnancy, comorbidity with psychiatric disorders and in younger and older people. Keywords Substance misuse, addiction, guidelines, pharmacotherapy, comorbidity Introduction guidelines (e.g.
    [Show full text]
  • Opioid and Nicotine Use, Dependence, and Recovery: Influences of Sex and Gender
    Opioid and Nicotine: Influences of Sex and Gender Conference Report: Opioid and Nicotine Use, Dependence, and Recovery: Influences of Sex and Gender Authors: Bridget M. Nugent, PhD. Staff Fellow, FDA OWH Emily Ayuso, MS. ORISE Fellow, FDA OWH Rebekah Zinn, PhD. Health Program Coordinator, FDA OWH Erin South, PharmD. Pharmacist, FDA OWH Cora Lee Wetherington, PhD. Women & Sex/Gender Differences Research Coordinator, NIH NIDA Sherry McKee, PhD. Professor, Psychiatry; Director, Yale Behavioral Pharmacology Laboratory Jill Becker, PhD. Biopsychology Area Chair, Patricia Y. Gurin Collegiate Professor of Psychology and Research Professor, Molecular and Behavioral Neuroscience Institute, University of Michigan Hendrée E. Jones, Professor, Department of Obstetrics and Gynecology; Executive Director, Horizons, University of North Carolina at Chapel Hill Marjorie Jenkins, MD, MEdHP, FACP. Director, Medical Initiatives and Scientific Engagement, FDA OWH Acknowledgements: We would like to acknowledge and extend our gratitude to the meeting’s speakers and panel moderators: Mitra Ahadpour, Kelly Barth, Jill Becker, Kathleen Brady, Tony Campbell, Marilyn Carroll, Janine Clayton, Wilson Compton, Terri Cornelison, Teresa Franklin, Maciej Goniewcz, Shelly Greenfield, Gioia Guerrieri, Scott Gottlieb, Marsha Henderson, RADM Denise Hinton, Marjorie Jenkins, Hendrée Jones, Brian King, George Koob, Christine Lee, Sherry McKee, Tamra Meyer, Jeffery Mogil, Ann Murphy, Christine Nguyen, Cheryl Oncken, Kenneth Perkins, Yvonne Prutzman, Mehmet Sofuoglu, Jack Stein, Michelle Tarver, Martin Teicher, Mishka Terplan, RADM Sylvia Trent-Adams, Rita Valentino, Brenna VanFrank, Nora Volkow, Cora Lee Wetherington, Scott Winiecki, Mitch Zeller. We would also like to thank those who helped us plan this program. Our Executive Steering Committee included Ami Bahde, Carolyn Dresler, Celia Winchell, Cora Lee Wetherington, Jessica Tytel, Marjorie Jenkins, Pamela Scott, Rita Valentino, Tamra Meyer, and Terri Cornelison.
    [Show full text]
  • A Molecular Basis for Nicotine As a Gateway Drug
    The new england journal of medicine special article shattuck lecture A Molecular Basis for Nicotine as a Gateway Drug Eric R. Kandel, M.D., and Denise B. Kandel, Ph.D. From the Howard Hughes Medical Insti- n the historic occasion of the 122nd Shattuck Lecture and tute (E.R.K.), Kavli Institute for Brain Sci- the 200th anniversary of the New England Journal of Medicine, we chose to ad- ence (E.R.K.), and the Departments of Neuroscience (E.R.K.) and Psychiatry Odress a topic that is at once scientific and personally historic. In recent (E.R.K., D.B.K.), College of Physicians debates over legalizing marijuana, from all-out acceptance in Colorado to narrow and Surgeons, and Mailman School of decriminalization in Maryland, the scientific question of the role of marijuana as a Public Health (D.B.K.), Columbia Univer- sity, and the New York State Psychiatric gateway drug (i.e., a drug that lowers the threshold for addiction to other agents) Institute (D.B.K.) — all in New York. Ad- has loomed large. Both opponents and proponents of legalization have distorted dress reprint requests to Dr. E. Kandel at what science does and does not tell us — and both sides have overlooked the im- the Department of Neuroscience, Col- lege of Physicians and Surgeons, Colum- portance of nicotine as a gateway drug. bia University, 1051 Riverside Dr., Unit Epidemiologic studies have shown that nicotine use is a gateway to the use of 87, New York, NY 10032, or at erk5@ marijuana and cocaine in human populations.
    [Show full text]
  • Opioid Antagonists for Smoking Cessation (Review)
    Opioid antagonists for smoking cessation (Review) David SP, Lancaster T, Stead LF, Evins AE, Cahill K This is a reprint of a Cochrane review, prepared and maintained by The Cochrane Collaboration and published in The Cochrane Library 2009, Issue 4 http://www.thecochranelibrary.com Opioid antagonists for smoking cessation (Review) Copyright © 2009 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd. TABLE OF CONTENTS HEADER....................................... 1 ABSTRACT ...................................... 1 PLAINLANGUAGESUMMARY . 2 BACKGROUND .................................... 2 OBJECTIVES ..................................... 3 METHODS ...................................... 3 RESULTS....................................... 4 Figure1. ..................................... 6 DISCUSSION ..................................... 7 AUTHORS’CONCLUSIONS . 8 ACKNOWLEDGEMENTS . 8 REFERENCES ..................................... 8 CHARACTERISTICSOFSTUDIES . 11 DATAANDANALYSES. 26 Analysis 1.1. Comparison 1 Naltrexone versus placebo (single pharmacotherapy or adjunct to NRT), Outcome 1 Abstinence atlongestfollowup. 26 WHAT’SNEW..................................... 27 HISTORY....................................... 27 CONTRIBUTIONSOFAUTHORS . 27 DECLARATIONSOFINTEREST . 28 SOURCESOFSUPPORT . 28 INDEXTERMS .................................... 28 Opioid antagonists for smoking cessation (Review) i Copyright © 2009 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd. [Intervention Review] Opioid antagonists for smoking cessation
    [Show full text]
  • GENETIC of ADDICTION: COMMON and UNCOMMON FACTORS Giada Juli1 & Luigi Juli2 1Catanzaro, Italy 2Mental Health Department, Catanzaro, Italy
    Psychiatria Danubina, 2015; Vol. 27, Suppl. 1, pp 383–390 Conference paper © Medicinska naklada - Zagreb, Croatia GENETIC OF ADDICTION: COMMON AND UNCOMMON FACTORS Giada Juli1 & Luigi Juli2 1Catanzaro, Italy 2Mental Health Department, Catanzaro, Italy SUMMARY Epidemiological studies strongly suggest that genetic factors operate at all steps of addictions, including vulnerability to initiation, continued use, and propensity to become dependent. Several studies have been popular to investigate the relative contributions of genetic and environmental factors, including the availability of and exposure to a substance, and shared and unique environments. The genetic influence on addiction has proved to be substantial, and heritabilities for most addictive disorders are moderate to high. In this work we evaluate the current status of data that analyzed genetic contribution in addictions. Key words: addictions- genetic factors-dependence * * * * * INTRODUCTION have analyzed alcohol addiction (or alcohol depen- dence) but the genetic influence have been evaluated Addiction is characterized by a compulsion to take a also for the susceptibility of tobacco addiction (or substance, with goal-directed behavior toward excessive dependence), cannabis, opioids and other psychoactive substance intake and a loss of control in limiting intake. substances. The aim of this review is to summarize the Recently, the Addictive Disorders have been enri- available literature that underly common and un- ched not only by synthetic substances of use/abuse, but common factors in genetic of addictions. also by behaviors capable to promote psychopatho- logical states which are disabling and serious. In fact, ALCOHOL DEPENDENCE (AD) apart from alcohol, tobacco, cocaine, cannabis, heroin and other substances, science has identified new addic- It is known that alcohol dependence (AD) can be tions such as Eating Disorders (Juli 2014), Gambling considered as a familiar trait with well characterized Addiction, Internet and Sex Addiction.
    [Show full text]
  • The Coâ•'Occurring Use and Misuse of Cannabis and Tobacco: a Review
    bs_bs_banner HORIZONS REVIEW doi:10.1111/j.1360-0443.2012.03837.x The co-occurring use and misuse of cannabis and tobacco: a reviewadd_3837 1221..1233 Arpana Agrawal1, Alan J. Budney2 & Michael T. Lynskey1 Department of Psychiatry,Washington University School of Medicine, Saint Louis, MO, USA1 and Department of Psychiatry, University of Arkansas for Medical Sciences, Little Rock, AR, USA2 ABSTRACT Aims Cannabis and tobacco use and misuse frequently co-occur. This review examines the epidemiological evidence supporting the life-time co-occurrence of cannabis and tobacco use and outlines the mechanisms that link these drugs to each other. Mechanisms include (i) shared genetic factors; (ii) shared environmental influences, including (iii) route of administration (via smoking), (iv) co-administration and (v) models of co-use. We also discuss respiratory harms associated with co-use of cannabis and tobacco, overlapping withdrawal syndromes and outline treatment implica- tions for co-occurring use. Methods Selective review of published studies. Results Both cannabis and tobacco use and misuse are influenced by genetic factors, and a proportion of these genetic factors influence both cannabis and tobacco use and misuse. Environmental factors such as availability play an important role, with economic models suggesting a complementary relationship where increases in price of one drug decrease the use of the other. Route of administration and smoking cues may contribute to their sustained use. Similar withdrawal syndromes, with many symptoms in common, may have important treatment implications. Emerging evidence suggests that dual abstinence may predict better cessation outcomes, yet empirically researched treatments tailored for co-occurring use are lacking.
    [Show full text]
  • Dependence Nicotine
    Nicotine Dependence Program 1 2 Contents Welcome . 4 Benefits of Quitting . 5 Dangerous Chemicals . 6 Carbon Monoxide . 7 Risks . 8 Health Problems . 9 Nicotine Addiction . 10 Nicotine Withdrawal . 11 Think About Making a Change . 12 Motivation . 13 Self-Care . 14 Preparing to Quit . 16 Medication Options . 18 Quit Day . 20 Appendix . 21 Triggers and Solutions . 22 Coping Strategies . 24 SMART Goals for Nutrition and Exercise . 25 Helpful Resources . 26 Tobacco Log . 27 3 Welcome! Welcome to Community Health Network’s Nicotine Dependence Program . We are glad you are here and eager to support your quit journey . Quitting is not easy and most people will need support . In the Nicotine Dependence Program we have individuals who have specialized training to help create an individualized plan specific to your needs and desire . We understand that there is not one way to quit and we desire to partner with you to create a unique quit plan that will work for you . What to expect We are here to support you and never judge you . We want to be your personal coach and guide you through your quit journey . The program will consist of 8 sessions over 16 weeks . 4 Benefits of Quitting Within 20 minutes of quitting… Within 20 minutes after your last cigarette your body begins a series of changes that will continue for many years . ➽ 20 minutes after ➽ 1 to 9 months after quitting, your heart quitting, your coughing rate drops . and shortness of breath ➽ 12 hours after quitting, decrease . the carbon monoxide ➽ 1 year after quitting, your level in your blood added risk of coronary drops to normal .
    [Show full text]
  • Opioid and Nicotine Use, Dependence, and Recovery: Influences of Sex and Gender
    Opioid and Nicotine Use, Dependence, and Recovery: Influences of Sex and Gender Health Policy, Research, Professional Education, and Clinical Care September 27-28, 2018 FDA White Oak Campus, Bldg. 31, Great Room Opioid and Nicotine Use, Dependence, and Recovery: Influences of Sex and Gender A INTRODUCTION Sex differences may influence susceptibility to substance use disorders, which could have implications for optimal prevention and treatment. Gender influences also impact public health by influencing prescription rates, care, and treatment-seeking behaviors. To identify and treat at-risk women, researchers, educators, and clinicians must be able to recognize and consider sex and gender differences in substance use, misuse, and recovery. The U.S. Food and Drug Administration’s Office of Women’s Health, in collaboration with the Center for Drug Evaluation and Research and Center for Tobacco Products, presents this 2-day meeting, Scientific Conference — Opioid and Nicotine Use, Dependence, and Recovery: Influences of Sex and Gender, to address this important issue. This conference will include presentations by experts in the fields of opioid and tobacco research, professional education, and clinical care on the biological (sex) and sociological (gender) influences on use, misuse, and recovery. LEARNING OBJECTIVES In relation to the sex and gender differences associated with opioid and nicotine use, dependence, and recovery, meeting participants will: Appreciate the sex and gender interactions in outcomes across the lifespan; understand the unique role of Health & Human Services (HHS) and other federal stakeholders; recognize research gaps and emerging therapeutic areas for drugs, devices, and behavioral approaches; recognize the necessity of a comprehensive, integrative approach to the treatment of addiction.
    [Show full text]