Proceedings OF THE National Academy of Sciences OF THE UNITED STATES OF AMERICA

May 1987 Volume 84, Number 10 pp. 3081-3536 Table of Contents

AUTHOR INDEX vii

Physical Sciences

CHEMISTRY Phytotoxins from the pathogenic fungi Drechslera maydis and Drechslera F. Sugawara, G. Strobel, R. N. Strange, 3081 sorghicola J. N. Siedow, G. D. Van Duyne, and J. Clardy Accessible surface areas as a measure of the thermodynamic parameters of Tatsuo Ooi, Motohisa Oobatake, George 3086 hydration of peptides Ndmethy, and Harold A. Scheraga Discrete wave mechanics: Multidimensional systems Frederick T. Wall 3091

MATHEMATICS Algebraic K-theory of discrete subgroups of Lie groups F. T. Farrell and L. E. Jones 3095

Biological Sciences BIOCHEMISTRY Specific inhibition of Trypanosoma cruzi neuraminidase by the human plasma R. P. Prioli, I. Rosenberg, and M. E. A. 3097 glycoprotein "cruzin" Pereira Regulation of actomyositl ATPase activity by troponin-tropomyosin: Effect of Lois E. Greene, David L. Williams, Jr., 3102 the binding of the myosin subfragment 1 (S-1) ATP complex and Evan Eisenberg

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Deduced amino acid sequence of bovine retinal Go.,: Similarities to other Krisa P. Van Meurs, C. William Angus, 3107 guanine nucleotide-binding proteins Sukadev Lavu, Hsiang-Fu Kung, Susanne K. Czarnecki, Joel Moss, and Martha Vaughan Cloning and DNA sequence of the mercuric- and organomercurial-resistance Hugh G. Griffin, Timothy J. Foster, 3112 determinants of plasmid pDU1358 Simon Silver, and Tapan K. Misra Sequences from a prokaryotic or the mouse dihydrofolate reductase Alison Baker and Gottfried Schatz 3117 gene can restore the import of a truncated precursor protein into yeast mitochondria Thyroid hormone regulates expression of a transfected a-myosin heavy-chain Thomas A. Gustafson, Bruce E. 3122 fusion gene in fetal heart cells Markham, Joseph J. Bahl, and Eugene Morkin Properties of the duplex DNA-dependent ATPase activity of Escherichia coli Stephen C. Kowalczykowski, Jennifer 3127 RecA protein and its role in branch migration Clow, and Renee A. Krupp Crystal structure of a snake venom cardiotoxin B. Rees, J. P. Samama, J. C. Thierry, 3132 M. Gilibert, J. Fischer, H. Schweitz, M. Lazdunski, and D. Moras Insulin stimulates phosphorylation of a 120-kDa glycoprotein substrate (ppl20) Nicola Perrotti, Domenico Accili, 3137 for the receptor-associated protein kinase in intact H-35 hepatoma cells Bernice Marcus-Samuels, Robert W. Rees-Jones, and Simeon I. Taylor Properties of a genetically engineered G domain of elongation factor Tu Andrea Parmeggiani, Guido W. M. 3141 Swart, Kim K. Mortensen, Michael Jensen, Brian F. C. Clark, Luciana Dente, and Riccardo Cortese Secretin stimulates cyclic AMP and inositol trisphosphate production in rat E. R. Trimble, R. Bruzzone, T. J. Biden, 3146 pancreatic acinar tissue by two fully independent mechanisms C. J. Meehan, D. Andreu, and R. B. Merrifield Synchrotron x-ray diffraction studies of actin structure during polymerization Paul Matsudaira, Joan Bordas, and 3151 M. H. J. Koch Cotranslational insertion of selenocysteine into formate dehydrogenase from F. Zinoni, A. Birkmann, W. Leinfelder, 3156 Escherichia coli directed by a UGA codon and A. Bock Temporal and tissue-specific expression of mouse ets genes Narayan K. Bhat, Robert J. Fisher, 3161 Shigeyoshi Fujiwara, Richard Ascione, and Takis S. Papas Apparent lack of discrimination in the reading of certain codons in Tore Samuelsson, Youssef S. Guindy, 3166 Mycoplasma mycoides Florentyna Lustig, Tomas Boren, and Ulf Lagerkvist Aberrant splicing events that are induced by proviral integration: Implications Dan Rosson, Debbie Dugan, and E. 3171 for myb oncogene activation Premkumar Reddy Reaction of argininosuccinase with bromomesaconic acid: Role of an essential C. J. Lusty and S. Ratner 3176 lysine in the active site A nonsense causes hereditary goitre in the Afrikander cattle and M. H. Ricketts, M. J. Simons, J. Parma, 3181 unmasks alternative splicing of thyroglobulin transcripts L. Mercken, Q. Dong, and G. Vassart Role of DNA topoisomerase I in the transcription of supercoiled rRNA gene Lalit C. Garg, Susan DiAngelo, and 3185 Samson T. Jacob Endonuclease IV of Escherichia coli is induced by paraquat Emily Chan and Bernard Weiss 3189 Identification and synthesis of a recognition signal for the attachment of Mario A. Bourdon, Tom Krusius, Steven 3194 glycosaminoglycans to proteins Campbell, Nancy B. Schwartz, and Erkki Ruoslahti lac repressor blocks in vivo transcription of lac control region DNA Marguerite A. Sellitti, Pamela A. Pavco, 3199 and Deborah A. Steege RNA from an immediate early region of the type 1 herpes simplex virus Anne M. Deatly, Jordan G. Spivack, 3204 genome is present in the trigeminal ganglia of latently infected mice Ehud Lavi, and Nigel W. Fraser Rat cellular retinol-binding protein: cDNA sequence and rapid David R. Sherman, R. Stephen Lloyd, 3209 retinol-dependent accumulation of mRNA and Frank Chytil Purification, properties, and immunocytochemical localization of human liver M. Kumudavalli Reddy, Nobuteru 3214 peroxisomal enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase Usuda, M. Narahari Reddy, Edward R. Kuczmarski, M. Sambasiva Rao, and Janardan K. Reddy Isolation of a cytochrome aa3 gene from Bradyrhizobium japonicum Mark R. O'Brian and Robert J. Maier 3219 ii Contents

Partial amino acid sequence of apolipoprotein(a) shows that it is homologous to Dan L. Eaton, Gunther M. Fless, 3224 plasminogen William J. Kohr, John W. McLean, Qin-Tu Xu, Chad G. Miller, Richard M. Lawn, and Angelo M. Scanu

BIOPHYSICS Single acetylcholine receptor channel currents recorded at high hydrostatic S. H. Heinemann, W. Stuhmer, and F. 3229 pressures Conti

CELL BIOLOGY Expression of p21mS in normal and malignant human tissues: Lack of Pilar Garin Chesa, Wolfgang J. Rettig, 3234 association with proliferation and malignancy Myron R. Melamed, Lloyd J. Old, and Henry L. Niman The very late family of heterodimers is part of a superfamily of Yoshikazu Takada, Jack L. Strominger, 3239 molecules involved in adhesion and embryogenesis and Martin E. Hemler Immunoglobulin A stimulates growth of the extrahepatic bile duct in BALB/c Sheila Fallon-Friedlander, Jeffrey R. 3244 mice Boscamp, Rachel Morecki, Frank Lilly, Marshall S. Horwitz, and Joy H. Glaser Cytoskeletal association of human a--receptor complexes in Lawrence M. Pfeffer, Nowell Stebbing, 3249 interferon-sensitive and -resistant lymphoblastoid cells and David B. Donner An insulin-like growth factor (IGF) binding protein enhances the biologic R. G. Elgin, W. H . Busby, Jr., and 3254 response to IGF-I D. R. Clemmons Periodic crosslinking of microtubules by cytoplasmic microtubule-associated Gregory T. Bramblett, Sulie Chang, and 3259 and microtubule-corset proteins from a trypanosomatid Martin Flavin Firefly luciferase is targeted to peroxisomes in mammalian cells Gilbert-Andre Keller, Stephen Gould, 3264 Marlene Deluca, and Suresh Subramani Functional epithelial cell line cloned from rat parathyroid glands Kazushige Sakaguchi, Arthur Santora, 3269 Mark Zimering, Francesco Curcio, Gerald D. Aurbach, and Maria Luisa Brandi Differential regulation of colony-stimulating factors and interleukin 2 M. Bickel, H. Tsuda, P. Amstad, V. 3274 production by cyclosporin A Evequoz, S. E. Mergenhagen, S. M. Wahl, and D. H. Pluznik Coinduction of glucose-regulated proteins and doxorubicin resistance in J. Shen, C. Hughes, C. Chao, J. Cai, C. 3278 Chinese hamster cells Bartels, T. Gessner, and J. Subjeck Growth factor(s) produced during infection with an adenovirus variant Margaret P. Quinlan, Neil Sullivan, and 3283 stimulates proliferation of nonestablished epithelial cells Terri Grodzicker Protein import into chloroplasts requires a chloroplast ATPase Debkumar Pain and Gunter Blobel 3288 A high molecular weight component of the human tumor necrosis factor Abla A. Creasey, Ralph Yamamoto, and 3293 receptor is associated with cytotoxicity Charles R. Vitt Chemical carcinogen-induced decreases in genomic 5-methyldeoxycytidine Vincent L. Wilson, Ruth A. Smith, Jim 3298 content of normal human bronchial epithelial cells Longoria, Mary Anne Liotta, Cynthia M. Harper, and Curtis C. Harris

DEVELOPMENTAL BIOLOGY Cell patterning in pigment-chimeric eyes in Xenopus: Germinal cell transplants R. Kevin Hunt, Jerry S. Cohen, and 3302 and their contributions to growth of the pigmented retinal epithelium Barbra J. Mason

EVOLUTION A molecular phylogeny of the hominoid primates as indicated by David Goldman, P. Rathna Giri, and 3307 two-dimensional protein electrophoresis Stephen J. O'Brien Geographic dialects in blind mole rats: Role of vocal communication in active Eviatar Nevo, Giora Heth, Avigdor 3312 speciation Beiles, and Eliezer Frankenberg i*i Contents

GENETICS Homology between the DNA-binding domain of the GCN4 regulatory protein Peter K. Vogt, Timothy J. Bos, and 3316 of yeast and the carboxyl-terminal region of a protein coded for by the Russell F. Doolittle oncogene jun A family of short, interspersed repeats is associated with tandemly repetitive Brion Mermer, Mark Colb, and 3320 DNA in the human genome Theodore G. Krontiris Random cloning of genes from mouse chromosome 17 Masanori Kasahara, Felipe Figueroa, and 3325 Jan Klein Structure and expression of human dihydropteridine reductase Jean Lockyer, Richard G. Cook, Sheldon 3329 Milstien, Seymour Kaufman, Savio L. C. Woo, and Fred D. Ledley Gene tandem-mediated selection of coliphage X-receptive Agrobacterium, Robert A. Ludwig 3334 Pseudomonas, and Rhizobium strains Detection of human DNA polymorphisms with a simplified denaturing gradient Walter W. Noll and Mary Collins 3339 gel electrophoresis technique Expression of retrovirally transduced genes in primary cultures of adult rat Jon A. Wolff, Jiing-Kuan Yee, Harold F. 3344 hepatocytes Skelly, Jane C. Moores, James G. Respess, Theodore Friedmann, and Hyam Leffert Comparative anatomy of the human APRT gene and enzyme: Nucleotide Thomas P. Broderick, Dennis A. Schaff, 3349 sequence divergence and conservation of a nonrandom CpG dinucleotide Amy M. Bertino, Michael K. Dush, arrangement Jay A. Tischfield, and Peter J. Stambrook Sequence analysis of spontaneous in a shuttle vector gene integrated Charles R. Ashman and Richard L. 3354 into mammalian chromosomal DNA Davidson Molecular cloning and characterization of esterase-6, a serine hydrolase of J. G. Oakeshott, C. Collet, R. W. Phillis, 3359 Drosophila K. M. Nielsen, R. J. Russell, G. K. Chambers, V. Ross, and R. C. Richmond Measurement of low levels of x-ray mutagenesis in relation to human disease Charles Waldren, Laura Correll, 3364 (Correction) Marguerite A. Sognier, and Theodore T. Puck

IMMUNOLOGY Molecular cloning of the CD2 antigen, the T-cell erythrocyte receptor, by a Brian Seed and Alejandro Aruffo 3365 rapid immunoselection procedure Biosynthesis, glycosylation, and partial N-terminal amino acid sequence of the Hans Reiser, John Coligan, Baruj 3370 T-cell-activating protein TAP Benacerraf, and Kenneth L. Rock Resistance of cytotoxic T lymphocytes to lysis by a clone of cytotoxic T David M. Kranz and Herman N. Eisen 3375 lymphocytes Regulation of murine class I genes by is controlled by regions Bette Korber, , and Iwona 3380 located both 5' and 3' to the transcription initiation site Stroynowski la,25-Dihydroxyvitamin D3 inhibits v-interferon synthesis by normal human Helmut Reichel, H. Phillip Koeffler, 3385 peripheral blood lymphocytes Andreas Tobler, and Anthony W. Norman Complete suppression of in vivo growth of human cells by specific Hideki Hara and Ben K. Seon 3390 immunotoxins: Nude mouse models Lymphocyte major histocompatibility complex-encoded class II structures may Ellyn R. Ashida and Virginia L. Scofield 3395 act as sperm receptors Working principles in the immune system implied by the "peptidic self' model Philippe Kourilsky, Gdrard Chaouat, 3400 Chantal Rabourdin-Combe, and Jean-Michel Claverie

MEDICAL SCIENCES Interferon y induces lung colonization by intravenously inoculated B16 K. Taniguchi, M. Petersson, P. Hoglund, 3405 melanoma cells in parallel with enhanced expression of class I major R. Kiessling, G. Klein, and K. Karre histocompatibility complex iv Contents

Recognition of tau by anti-neurofilament that bind to Hanna Ksiezak-Reding, Dennis W. 3410 Alzheimer neurofibrillary tangles Dickson, Peter Davies, and Shu-Hui Yen Recognition of Alzheimer paired helical filaments by monoclonal neurofilament Nobuyuki Nukina, Kenneth S. Kosik, 3415 antibodies is due to crossreaction with tau protein and Dennis J. Selkoe Purification and characterization of rat liver nuclear thyroid hormone receptors Kazuo Ichikawa and Leslie J. DeGroot 3420 Development of a monoclonal specifically reactive to gastrointestinal M. Vecchi, S. Sakamaki, B. Diamond, 3425 goblet cells A. B. Novikoff, P. M. Novikoff, and K. M. Das Linkage of the Wiskott-Aldrich syndrome with polymorphic DNA sequences Monica Peacocke and Katherine A. 3430 from the human X chromosome Siminovitch Glucagon-like peptide I stimulates insulin gene expression and increases cyclic Daniel J. Drucker, Jacques Philippe, 3434 AMP levels in a rat islet cell line Svetlana Mojsov, William L. Chick, and Joel F. Habener Chimeric mouse-human IgG1 antibody that can mediate lysis of cancer cells Alvin Y. Liu, Randy R. Robinson, Karl 3439 Erik Hellstrom, E. David Murray, Jr., C. Paul Chang, and Ingegerd Hellstrom Androstenedione may organize or activate sex-reversed traits in female spotted Stephen E. Glickman, Laurence G. 3444 hyenas Frank, Julian M. Davidson, Erla R. Smith, and P. K. Siiteri Monoclonal antibodies to the human insulin receptor that activate glucose John R. Forsayeth, Jose F. Caro, 3448 transport but not insulin receptor kinase activity Madhur K. Sinha, Betty A. Maddux, and Ira D. Goldfine Epstein-Barr virus nuclear antigen 2 specifically induces expression of the F. Wang, C. D. Gregory, M. Rowe, 3452 B-cell activation antigen CD23 A. B. Rickinson, D. Wang, M. Birkenbach, H. Kikutani, T. Kishimoto, and E. Kieff Tissue distribution and clearance kinetics of non-transferrin-bound iron in the C. M. Craven, J. Alexander, M. 3457 hypotransferrinemic mouse: A rodent model for hemochromatosis Eldridge, J. P. Kushner, S. Bernstein, and J. Kaplan MICROBIOLOGY Isolation and characterization of the a-sialyl-,-2,3-galactosyl-specific adhesin Thomas Moch, Heinz Hoschutzky, Jorg 3462 from fimbriated Escherichia coli Hacker, Klaus-D. Kroncke, and Klaus Jann

NEUROBIOLOGY Cholinergic phosphatidylinositol modulation of inhibitory, G protein-linked, Paul F. Worley, Jay M. Baraban, 3467 neurotransmitter actions: Electrophysiological studies in rat hippocampus Madeline McCarren, Solomon H. Snyder, and Bradley E. Alger Neurofilament gene expression: A major determinant of axonal caliber Paul N. Hoffman, Don W. Cleveland, 3472 John W. Griffin, Phillip W. Landes, Nicholas J. Cowan, and Donald L. Price Calcium-dependent effect of the thymic polypeptide thymopoietin on the Frederic Revah, Christophe Mulle, 3477 desensitization of the nicotinic acetylcholine receptor Christian Pinset, Tapan Audhya, Gideon Goldstein, and Jean-Pierre Changeux Monoclonal antibody analysis of keratin expression in the central nervous Maryellen C. Franko, Clarence J. Gibbs, 3482 system Jr., Dorothy A. Rhoades, and D. Carleton Gajdusek Multiple neuropeptides in cholinergic motor neurons of Aplysia: Evidence for Elizabeth C. Cropper, Philip E. Lloyd, 3486 modulation intrinsic to the motor circuit William Reed, Renata Tenenbaum, Irving Kupfermann, and Klaudiusz R. Weiss Quinolinic acid phosphoribosyltransferase: Preferential glial localization in the Christer Koihler, Etsuo Okuno, Per R. 3491 rat brain visualized by immunocytochemistry Flood, and Robert Schwarcz Activation of a potassium current by rapid photochemically generated step Alison M. Gurney, Roger Y. Tsien, and 3496 increases of intracellular calcium in rat sympathetic neurons Henry A. Lester

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t-Aminobutyric acid exerts a local inhibitory action on the axon terminal of Masao Tachibana and Akimichi Kaneko 3501 bipolar cells: Evidence for negative feedback from amacrine cells Identification and purification of an irreversible presynaptic neurotoxin from Chauncey W. Bowers, Heidi S. Phillips, 3506 the venom of the spider Hololena curta Pamela Lee, Yuh Nung Jan, and Lily Y. Jan Neuropeptide Y-like immunoreactivity in rat cranial parasympathetic neurons: Gabrielle G. Leblanc, Barry A. Trimmer, 3511 Coexistence with vasoactive intestinal peptide and choline acetyltransferase and Story C. Landis Cloning and sequence analysis of cDNA for the canine Paul R. Dobner, Diane L. Barber, Lydia 3516 neurotensin/neuromedin N precursor Villa-Komaroff, and Colleen McKiernan Correlation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity with Rajesh N. Kalaria, Mary Jo Mitchell, 3521 blood-brain barrier monoamine oxidase activity and Sami I. Harik Human immunodeficiency virus can productively infect cultured human glial Cecilia Cheng-Mayer, James T. Rutka, 3526 cells Mark L. Rosenblum, Thomas McHugh, Daniel P. Stites, and Jay A. Levy

Social Sciences PSYCHOLOGY Initial localization of the acoustic conditioned stimulus projection system to the Joseph E. Steinmetz, Christine G. 3531 cerebellum essential for classical eyelid conditioning Logan, Daniel J. Rosen, Judith K. Thompson, David G. Lavond, and Richard F. Thompson

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