Wednesday April 10, 2019 11.30 – 12.30 Registration 12.30 – 12.45 Introduction Laurent Kaiser Head of Division of Infectious Diseases, University Hospital Geneva, Faculty of Medicine University of Geneva, Switzerland

Henri Bounameaux Dean of the Faculty of Medicine University of Geneva, Switzerland Session I: Arbovirus Emergence in Europe

Chairs: Shindo Nahoko (World Health Organization), Pascal Cherpillod (University Hospital Geneva)

12.45 – 12.55 A Case of Autochthonous CCHF Jose Arribas Transmission in Spain Hospital Universitario La Paz, Madrid, Spain 12.55 – 13.15 CCHF in Europe – Lessons from Tom Fletcher Turkey Liverpool School of Tropical Medicine, Liverpool, UK 13.15 – 13.35 Mayaro, Usutu, West Nile - the Jonas Schmidt-Chanasit Next Emerging Arbovirus? Bernhard-Nocht-Institute Hamburg, Germany 13.35 – 13.50 Discussion 13.50 – 14.20 Coffee Break Session II: Yellow Fever Virus – Old Virus, New Challenges

Chairs: François Chappuis (Faculty of Medicine University of Geneva and Geneva University Hospitals), Amadou Sall (Institute Pasteur Dakar)

14.20 – 14.30 A Case of Imported Yellow Fever Annelies Zinkernagel in Switzerland University Hospital Zurich, Switzerland 14.30 – 14.50 Severe Yellow Fever – Clinical Ho Yeh Li Experience from Brazil University of Sao Paulo, Brazil 14.50 – 15.10 Epidemiology & Ecology of the Jan Felix Drexler YFV Outbreak – why now? Charité Berlin, Germany 15.10 – 15.25 Discussion 15.25 – 15.50 Break Evening Lectures 15.50 – 16.10 Welcome Note Isabella Eckerle Geneva Centre for Emerging Viral Diseases, Geneva, Switzerland

Bertrand Levrat General Director, University Hospital Geneva 16.15 - 16.45 Snakebite: From Research to François Chappuis Public Health Interventions University Hospital Geneva, Switzerland 16.45 -17.15 Crisis Management in Emergency Esperanza Martinez Situations International Committee of the Red Cross, Geneva, Switzerland Social Program 18.00 Guided Tour of the International Red Cross Museum & Apero

1 Thursday April 11, 2019 Session I: Vaccines for Emerging Viruses – the Long and Winding Road to Protection

Chairs: Olivia Keiser (Institute of Global Health Geneva), Ana Rita Gonçalves Cabecinhas (University Hospital Geneva) 08.30 – 8.50 The Ups and Downs of Dengue Annelies Wilder-Smith Vaccination Initiative for Vaccine Research, WHO, Geneva, Switzerland 08.50 - 09.10 Evolutionary Dynamics of Colin Russell Influenza Viruses Academic Medical Center of the University of Amsterdam, The Netherlands 09.10 – 9.25 Discussion Session II: Emerging Virus of Global Relevance: Measles, HIV and Enteric Viruses

Chairs: Klara Posfay-Barbe (Faculty of Medicine University of Geneva and Geneva University Hospitals), Volker Thiel (University Bern) 09.30 - 09.50 Measles Epidemiology – Sabine Santibanez Drawbacks and Current Robert Koch Institute, Germany Challenges 09.50 – 10.10 HIV Control : Unresolved and Alexandra Calmy Emerging Issues Faculty of Medicine University of Geneva and Geneva University Hospitals, Switzerland 10.10 – 10.30 The Rapidly Evolving World of Marion Koopmans Enteric Viruses Erasmus Medical Centre, Rotterdam, The Netherlands 10.30 – 10.45 Discussion 10.45 – 11.15 Coffee break Session III: Novel Approaches to Tackle Emerging Viruses

Chairs: Manuel Schibler (University Hospital Geneva), Noël Tordo (Institute Pasteur Guinea)

11.20 – 11.30 A Mobile Laboratory for Outbreak Rudi Pauwels Situations Praesens Foundation, Belgium 11.30 - 11.50 Precision Global Health – Antoine Flahault Forecasting Outbreaks? Institute of Global Health, Faculty of Medicine University of Geneva, Switzerland 11.50 – 12.05 Discussion Session IV: Ebola - Recent Challenges and New Approaches

Chairs: Olivier Engler (Federal Office for Civil Protection Switzerland), Daniel Bausch (London School of Tropical Medicine and Hygiene) 12.10 – 12.20 Ebola in DRC – a clinical point of Pauline Vetter view University Hospital Geneva, Switzerland 12.20 - 12.40 Challenges of the current Ebola Pierre Formenty outbreak in DRC World Health Organisation, Geneva, Switzerland 12.40 – 12.55 Discussion 12.55 - 14.30 Lunch Venue: Foyer, Campus Biotech

2 Session V: Emerging Rodent-borne Viruses: Lassa and Hantaviruses

Chairs: Gary Kobinger (University Laval), Stefan Kunz (University Hospital Lausanne) 14.30 – 14.40 A Case of Imported New World Cornelia Staehelin Hantavirus Infection to University Hospital Bern, Switzerland Switzerland 14.40 – 14.50 A Case of Imported Lassa Virus Timo Wolf Case to Germany Goethe University Frankfurt, Germany 14.50 – 15.10 Lassa – Lessons from the Field Daniel Bausch London School of Tropical Medicine & Hygiene, London, UK 15.10 – 15.30 Novel Diagnostics for Lassa Virus Stephan Günther in the Field Bernhard Nocht Institute Hamburg, Germany 15.30 – 15.45 Discussion 15.45 – 16.15 Coffee break Keynote Lectures: Virus Discovery – the Anticipation of the Next Pandemic?

Chairs: Antoine Flahault (Institute of Global Health), Isabella Eckerle (University Hospital Geneva)

16.10 - 16.45 Expansion of the RNA Virosphere Edward Holmes University of Sydney, Australia 16.45 - 17.15 Microbial Discovery, Surveillance, W. Ian Lipkin and Diagnostics Columbia University, New York, USA 17.15 – 17.45 PREDICT and the Global Virome Peter Daszak project Ecohealth Alliance, New York, USA 17.45 – 18.15 Anticipation of the next pandemic Plenary Discussion – How can we do better? Social program 19.30 Conference Dinner Restaurant Vieux-Bois

Friday April 12, 2019 Session I: Emerging Viruses and the Brain

Chairs: Philip Le Mercier (Swiss Institute of Bioinformatics), Samuel Cordey (University Hospital Geneva)

08.30 - 08.50 The South East Asian Marc Lecuit Encephalitis Project Pasteur Institute Paris, France

08.50 – 09.10 Rabies Risk in Europe and Hervé Bourhy Beyond Pasteur Institut Paris, France 09.10 – 09.25 Discussion Session II: Emerging Viruses from Africa

Chairs: Pauline Vetter (University Hospital Geneva), Cassandra Kelly (Foundation for Innovative New Diagnostics) 09.30 - 09.50 Imported Monkeypox to the UK Michael Jacobs Royal Free Hospital, London, UK 09.50 – 10.10 Arboviruses in Africa – Lessons Amadou Sall from Senegal Pasteur Institute Dakar, Senegal

3 10.10 – 10.25 Discussion 10.25 – 10.55 Coffee break Session III: Climate Change and the Impact on Emerging Viruses

Chairs: Rafael Ruiz de Castañeda (Institute of Global Health Geneva), Micaela Serafini (Médecins Sans Frontières) 11.00 - 11.20 Climate Change and Health in Rainer Sauerborn Poor Countries Institute of Public Health, Heidelberg, Germany 11.20 – 11.40 Rift-Valley-fever Outbreak Assaf Anyamba Assessment by Satellite-based University Space Research Association & NASA, Land Surface Analysis Goddard Space Flight Center, USA 11.40 – 11.55 Discussion Session IV: Febrile Illness – the Clinical Approach

Chairs: Jérôme Pugin (Faculty of Medicine University of Geneva and Geneva University Hospitals), Marylyn Addo (University Hospital Hamburg) 11.55 – 12.15 Febrile Illnesses - What if it is not Daniel Paris a Virus? Swiss TPH, Basle, Switzerland Award lecture 12.15 – 12.30 Award Ceremony Laurent Kaiser Faculty of Medicine University of Geneva and Geneva University Hospitals, Switzerland 12.30 – 13.00 Emerging pathogens then and Pierre Rollin, now - Three decades of hunting Formerly Centers for Disease Control and deadly viruses Prevention, Atlanta, USA 13.00-13.30 A Research Journey through Gary Kobinger Emerging Viruses University Laval, Quebec, Canada 13.30 - 13.45 Closing Remarks & Farewell Laurent Kaiser Head of Division of Infectious Diseases, Faculty of Medicine University of Geneva and Geneva University Hospitals Switzerland

Isabella Eckerle Geneva Centre for Emerging Viral Diseases, Faculty of Medicine University of Geneva and Geneva University Hospitals, Switzerland

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