Recombinant Human S100A4

PA1374 OriGene Technologies Inc. OriGene EU

Acris Antibodies GmbH 9620 Medical Center Drive, Ste 200 Schillerstr. 5 Rockville, MD 20850 32052 Herford UNITED STATES GERMANY Phone: +1-858-888-7900 Phone: +49-5221-34606-0 Fax: +1-858-888-7904 Fax: +49-5221-34606-11 [email protected] [email protected]

Recombinant Human S100A4 Alternate names: CAPL, Calvasculin, FSP-1, FSP1, Fibroblast marker, Fibroblast specific protein-1, MTS1, Metastasin, Placental Calcium-Binding Protein, S100 Calcium-Binding Protein A4, S100-A4 Catalog No.: PA1374 Quantity: 2 µg Concentration: 0.1 mg/ml Background: S100A4 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 belongs to the family of calcium binding proteins such as calmodulin and troponin C. S100A is composed of an alpha and beta chain whereas S100B is composed of two beta chains. S100 protein is also expressed in the antigen presenting cells such as the Langerhans cells in skin and interdigitating reticulum cells in the paracortex of lymph nodes. S100 proteins are localized either in the cytoplasm or the nucleus of a wide range of cells. S100 proteins are involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100A4 may function in motility, invasion, and tubulin polymerization. There are at least 13 members in the S100 gene family, which are located as a cluster on chromosome 1q21. Chromosomal rearrangements and altered expression of the S100A4 gene have been implicated in tumor metastasis. Uniprot ID: P26447 NCBI: NP_002952.1 GeneID: 6275 Species: Human Source: E. coli Format: State: Liquid (sterile filtered) purified Protein Buffer System: 50mM Tris-Acetate, pH7.5, 1mM EDTA, 20% Glycerol without BSA and Sodium Azide Applications: ELISA. Inhibition Assays. Western Blotting. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user. Description: S100A4 Human Recombinant full length protein expressed in E.coli is antibody reactive. S100A4 is fused to a GST tag. The S100A4 is purified by proprietary chromatographic techniques. Storage: Store the protein at -20°C to -80°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

For research and in vitro use only. Not for diagnostic or therapeutic work. OG/20121030 Material Safety Datasheets are available at www.acris-antibodies.com or on request. Acris Antibodies is now part of the OriGene family. Learn more at www.origene.com 1 / 1