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KOBE Biomedical Innovation Cluster Start in Kobe. Innovate in Kobe. KOBE Biomedical Innovation Cluster Business Launch Support Guide Foundation for KOBE Biomedical Innovation Cluster Biomedical Research and Innovation at Kobe (FBRI) The City of Kobe launched the Kobe Biomedical Innovation Cluster (KBIC) as a recovery project to rebuild the As a core support organization of Kobe Biomedical Innovation Center, FBRI aims to create economy of Kobe, which was severely damaged by the Great Hanshin-Awaji Earthquake that occurred on January 17, groundbreaking medical technologies and innovations by promoting collaboration and integration 1995. Since 1998, the City of Kobe has developed an R&D hub for advanced medical technology on Port Island, an among industries, universities and the governmental and life science sectors, to become Asia’s artificial island, and through collaboration among industries, universities and the governmental and medical sectors, it leading biomedical cluster. Dr. Tasuku Honjo, President has built up a cluster of medical-related industries that will be the growth engine for the life sciences industry in the 21st century. To date, it has grown to become Japan's largest biomedical cluster with a concentration of about 370 Organizations cutting-edge research institutes, highly specialized hospitals, medical-related companies and universities. Institute of Biomedical Translational Research Research and Center for Cluster Research and Center for Medical Development Center Development and Innovation(IBRI) Innovation(TRI) for Cell Therapy (RDC) Coordination (CCD) Creation of new medical seeds with Support for the development of Global standardization of regenera- Providing one-stop services to respond a focus on "immunology R&D," new medical seeds in Japan and tive medicine from Kobe through to a wide range of support needs in a "R&D, for the aging" and "regenera- overseas, with a focus on the the development of a next-genera- centralized manner, from the identifica- tive medicine R&D” research and development seeds tion cell cultivation systems, etc. tion of seeds to intellectual property, Clusters Aimed at Creating Innovation of FBRI pharmaceutical consultations, and sales channel development A concentration of about 370 companies and organizations Business Incubation and Research Division Practical Application Promotion Division Collaboration Liaison Office ● Research institutes, hospitals, and companies are concentrated in a compact area, creating a variety of innovations through collaboration ● A concentration of contract research organizations, contract testing organizations, CROs, CMOs, and animal breeding and experimentation facilities to respond to a variety of research and development needs ● The Translational Research Informatics Center (TRI) supports clinical research and collaborates with nine highly specialized hospital clusters to create an environment conducive to clinical research Full support system Companies/organizations: 369 (Feb. 2020) ● Expanding support for startups by providing, among others, various incubation facilities and acceleration programs Company and Organization Number of employees: About 11,000 (Mar. 2019) ● Kobe City staff, together with dedicated coordinators, provide support for the commercialization for expanding businesses and support for individual company matching Shift in employee numbers Breakdown of companies/ ● PMDA Pharmaceutical Affairs Strategic Consultation is available for company and organization organizations As of end of Feb. 2020 12000 400 352 11000 IT & software Clinical 5.1% 336 350 Logistics Medical institutions Basic Research Institutions 10000 Number of employees 2.2% 2.7% Number of companies/ 9000 organizations 300 271 Other 8000 7.6% Research Hospitals 250 institutes 7000 Medical devices 203 27.1% INNOVATION 6000 200 R&D support 5000 16.3% Foundation for Biomedical Kobe City 150 Pharmaceutical / Research and Innovation (FBRI) Medical Center General Hospital 4000 125 Biotechnology Institute of Biomedical Research 15.2% and Innovation (IBRI) 3000 100 Kobe City Eye Hospital 73 Translational Research Center for Universities & Medical Innovation (TRI) 2000 10,000 Industrialization 11,000 Academic groups 4,300 2,200 1,600 7,50 0 50 Research & Development Center for Kobe Proton Center 3.5% Cell Therapy (RDC) 1000 18 Regenerative 200 Nursing care & Healthcare medicine Nishi Memorial 0 0 rehabilitation 7.6% RIKEN Port Island Rehabilitation Hospital 2001 2004 2007 2010 2013 2016 2018 4.1% 8.7% RIKEN Center for Companies Biosystems Dynamics Research (BDR) International Clinical Cancer RIKEN Center for Research Center List of foreign companies Computational Science (R-CCS) United States Germany Pharmaceutical and Biomedical Child Chemo House Nihon Medi-Physics, Bay Biosciences, Johnson & Johnson, Nippon Boehringer Ingelheim, Kobe University Progenicyte Japan, Zimmer Biomet, Simco Japan, Siemens Japan, IQVIA Services Japan, Double Helix International Bayer Yakuhin, Dürr Dental Japan University of Hyogo Regenerative medicine Kobe Minimally Invasive Cancer Center Konan University Medical devices Italy China Belgium Korea Kobe Gakuin University Hyogo Prefectural Copan Japan BGI Japan IBP Technologies Dexcowin Japan Kobe Children’s Hospital Hyogo University of Health Sciences Nursing care and welfare Switzerland United Kingdom Kobe Women’s University / SKANJAPAN, Electrosuisse Japan, Fischer Connectors Spectris, Freeman Technology Kobe Women’s Junior College Healthcare Anshin Hospital 1 2 Enhanced Business Environment ～Initiatives at KBIC to support commercialization～ Business Support for KBIC Companies and Organizations Platform to 45 examples of 4 programs Promote Medical commercialization Drug Discovery implemented Device Commercialization Innovation Program One-stop service ● Support for development projects (accompanied or spot consultations) Supporting one-stop drug discovery and development by coordinating the ● Medical device business seminars researchers, surrounding facilities and clinical environment necessary for A dedicated coordinator serves as a guide to provide ● Study sessions about pharma and device laws, and more drug development. comprehensive support for the market research, R&D, pharmaceutical affairs, and developing sales channels Promoting Development/Introduction Healthcare Service of Nursing and Development Unfamiliar with Medical Robots Support Support Business the rules because with various 2,283 ● Cooperation with nursing care facilities ● Advice on development and improvement no connections in the Accompanied support by dedicated coordinators options citizen supporters ▲ ▲ ▲ Development subsidies for nursing/medical robots Matching companies and researchers medical community Insufficient Pharmaceutical Medical devices Healthcare ● ● (as of Feb. 2020) knowledge about ▲ Startups ▲ International expansion ● Comprehensive support desk for nursing/medical robots ● Healthcare citizen support system No marketing pharma regulations ▲ Industry-university cooperation capability at clinical environment Kobe Recruiting new members! Industrial Use of the Research Complex Program Supercomputer (Fugaku, FOCUS) KBIC Liaison Office The aim is to create a healthcare ecosystem in Kobe by gathering healthcare Achieving simulation of innovative medical technology by promoting spread Consulting party Dedicated coordinators offer consultations about, among other things, seeds and needs from across the country with a focus on the "Health Function" companies / of large-scale, high-accuracy analysis and technology advancement. organizations the practical application and commercialization of your R&D seeds. and "Data HUB" projects, and supporting companies’ commercialization through joint creation among industry-university-government-funded projects. ▲ New participating companies ▲ Medical device-related companies Research Hospital ▲ Market Bioresource Center, Pharma & regeneration medicine-related research Accompanied consultation starts! Kobe University International Clinical companies Cancer Research Center (ICCRC) Kobe University Hospital ▲ Seeds & needs Clinicians & researchers As a place for joint research between medical professionals and matching Creates evidence for the development of therapeutics, diagnostics and companies/researchers, this research base can be used as a base for medical devices through the use of bioresources (human specimens developing new medical devices by both large companies and start-up companies. +clinical information). Cooperation/ Business Support for Startups consultation desk with medical institutions Provide optimal support for your startup needs. A consultation/cooperation desk for companies, research institutes, and Concept universities for collaboration with medical institutions located at KBIC. design Consultations about clinical trials, clinical research and joint R&D. Focused support the early stages Experts, including patent lawyers Seed Early Expansion Later Development Clinicians & researchers & Testing PMDA Strategic Consultation & Cooperation Center ・Regulatory science strategic consultation by PMDA staff Accompanied coordinators provide necessary support 2017 8 Drug 201 Conduct comprehensive regulatory science consultation 9 201 ・ approval ・Pre-consultation handling of various issues and topics Acceleration program KOBE Medtech Grand Prix KOBE application PMDA staff People Lab Money Human Resources Activity Base Subsidies Sales Development ● Incubation Lab (CLIK, 2nd Fl.) ● Kobe Life Science Gap Fund Real-time PCR, all-in-one fluorescence microscope,
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