Anti-TNFAIP1 (internal region) polyclonal antibody (DPABH-27067) This product is for research use only and is not intended for diagnostic use.
PRODUCT INFORMATION
Antigen Description Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(BACURD2) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration. Its interaction with RHOB may regulate apoptosis. May enhance the PCNA-dependent DNA polymerase delta activity.
Immunogen Synthetic peptide corresponding to the internal region of Human TNFAIP1.
Isotype IgG
Source/Host Rabbit
Species Reactivity Human
Purification Immunogen affinity purified
Conjugate Unconjugated
Applications WB
Format Liquid
Size 100 μg
Buffer pH: 7.40; Constituents: 49% PBS, 50% Glycerol, 0.88% Sodium chloride. Note: PBS is without Mg2+ and Ca2+
Preservative 0.02% Sodium Azide
Storage Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
GENE INFORMATION
Gene Name TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial) [ Homo sapiens ]
Official Symbol TNFAIP1
Synonyms TNFAIP1; tumor necrosis factor, alpha-induced protein 1 (endothelial); EDP1; BTB/POZ domain-
45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]
Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved containing adapter for CUL3-mediated RhoA degradation protein 2; B12; B61; MGC2317; BTB/POZ domain-containing protein TNFAIP1; hBACURD2;
Entrez Gene ID 7126
Protein Refseq NP_066960
UniProt ID Q13829
Chromosome Location 17q22-q23
Function GTP-Rho binding; protein binding; contributes_to ubiquitin-protein ligase activity; voltage-gated potassium channel activity;
45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]
Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved