Efficacy and Safety of TOBI Podhaler in Pseudomonas Aeruginosa-Infected Bronchiectasis Patients: Ibest Study
ORIGINAL ARTICLE BRONCHIECTASIS Efficacy and safety of TOBI Podhaler in Pseudomonas aeruginosa-infected bronchiectasis patients: iBEST study Michael R. Loebinger1,2, Eva Polverino3, James D. Chalmers4, Harm A.W.M. Tiddens5,6, Herman Goossens7, Michael Tunney8, Felix C. Ringshausen 9, Adam T. Hill10, Rashidkhan Pathan11, Gerhild Angyalosi12, Francesco Blasi 13,14, Stuart J. Elborn2,15,16 and Charles S. Haworth17,18 on behalf of the iBEST-1 Trial Team Affiliations: 1Host Defence Unit, Royal Brompton Hospital and Harefield NHS Foundation Trust, London, UK. 2Imperial College London, London, UK. 3Respiratory Disease Department, Vall d’ Hebron University Hospital – VHIR, Barcelona, Spain. 4Scottish Centre for Respiratory Research, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK. 5Dept of Paediatric Pulmonology and Allergology, Erasmus Medical Centre Sophia Children’s Hospital, Rotterdam, The Netherlands. 6Dept of Radiology and Nuclear Medicine, Erasmus Medical Centre, Rotterdam, The Netherlands. 7Dept of Clinical Microbiology, University Hospital Antwerp, Antwerp, Belgium. 8Halo Research Group, School of Pharmacy, Queen’s University Belfast, Belfast, UK. 9Dept of Respiratory Medicine, Hannover Medical School, and Biomedical Research in End-stage and Obstructive Lung Disease Hannover (BREATH), German Center for Lung Research (DZL), Hannover, Germany. 10Dept of Respiratory Medicine, Royal Infirmary of Edinburgh, and University of Edinburgh, Edinburgh, UK. 11Novartis Healthcare Private Limited, Hyderabad, India. 12Novartis Pharma AG, Basel, Switzerland. 13Internal Medicine Dept, Respiratory Unit and Adult Cystic Fibrosis Center, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milan, Italy. 14Dept of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy. 15Halo Research Group, Centre for Experimental Medicine, Queen’s University Belfast, Belfast, UK. 16Imperial College and Royal Brompton Hospital and Harefield NHS Foundation Trust, London, UK.
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