DOCSLIB.ORG

Trichoderma Reesei Strains for Production of Cellulases for the Textile Industry

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Trichoderma Reesei Strains for Production of Cellulases for the Textile Industry ESPOO 2004 VTT PUBLICATIONS 550 VTT PUBLICATIONS VTT PUBLICATIONS 550 529 Aikio, Janne K. Extremely short external cavity (ESEC) laser devices. Wavelength tuning and related optical characteristics. 2004. 162 p. 530 FUSION Yearbook. Association Euratom-Tekes. Annual Report 2003. Ed. by Seppo Karttunen & Karin Rantamäki. 2004. 127 p. + app. 10 p. 12345678901234567890123456789012123456789012345678901234567890121234567890123456 12345678901234567890123456789012123456789012345678901234567890121234567890123456 12345678901234567890123456789012123456789012345678901234567890121234567890123456 531 Toivonen, Aki. Stress corrosion crack growth rate measurement in high temperature water 12345678901234567890123456789012123456789012345678901234567890121234567890123456 12345678901234567890123456789012123456789012345678901234567890121234567890123456 using small precracked bend specimens. 2004. 206 p. + app. 9 p. 12345678901234567890123456789012123456789012345678901234567890121234567890123456 12345678901234567890123456789012123456789012345678901234567890121234567890123456 12345678901234567890123456789012123456789012345678901234567890121234567890123456 12345678901234567890123456789012123456789012345678901234567890121234567890123456 532 Moilanen, Pekka. Pneumatic servo-controlled material testing device capable of operating 12345678901234567890123456789012123456789012345678901234567890121234567890123456 12345678901234567890123456789012123456789012345678901234567890121234567890123456 12345678901234567890123456789012123456789012345678901234567890121234567890123456 at high temperature water and irradiation conditions. 2004. 154 p. 12345678901234567890123456789012123456789012345678901234567890121234567890123456 12345678901234567890123456789012123456789012345678901234567890121234567890123456 12345678901234567890123456789012123456789012345678901234567890121234567890123456 Trichoderma reesei 12345678901234567890123456789012123456789012345678901234567890121234567890123456 533 Pinto, Isabel. Raw material characteristics of maritime pine (Pinus pinaster Ait.) and their 12345678901234567890123456789012123456789012345678901234567890121234567890123456 12345678901234567890123456789012123456789012345678901234567890121234567890123456 12345678901234567890123456789012123456789012345678901234567890121234567890123456 influence on simulated sawing yield. 2004. 51 p. + app. 69 p. 12345678901234567890123456789012123456789012345678901234567890121234567890123456 12345678901234567890123456789012123456789012345678901234567890121234567890123456 12345678901234567890123456789012123456789012345678901234567890121234567890123456 534 Kallio, Päivi. Emergence of Wireless Services. Business Actors and their Roles in 12345678901234567890123456789012123456789012345678901234567890121234567890123456 12345678901234567890123456789012123456789012345678901234567890121234567890123456 12345678901234567890123456789012123456789012345678901234567890121234567890123456 Networked Component-based Development. 2004. 118 p. + app. 71 p. 12345678901234567890123456789012123456789012345678901234567890121234567890123456 12345678901234567890123456789012123456789012345678901234567890121234567890123456 12345678901234567890123456789012123456789012345678901234567890121234567890123456 12345678901234567890123456789012123456789012345678901234567890121234567890123456 535 Komi-Sirviö, Seija. Development and Evaluation of Software Process Improvement 12345678901234567890123456789012123456789012345678901234567890121234567890123456 12345678901234567890123456789012123456789012345678901234567890121234567890123456 12345678901234567890123456789012123456789012345678901234567890121234567890123456 Methods. 2004. 175 p. + app. 78 p. 12345678901234567890123456789012123456789012345678901234567890121234567890123456 12345678901234567890123456789012123456789012345678901234567890121234567890123456 12345678901234567890123456789012123456789012345678901234567890121234567890123456 12345678901234567890123456789012123456789012345678901234567890121234567890123456 536 Heinonen, Jaakko. Constitutive Modeling of Ice Rubble in First-Year Ridge Keel. 2004. 12345678901234567890123456789012123456789012345678901234567890121234567890123456 strains for production of cellulases for the textile industry strains for production 12345678901234567890123456789012123456789012345678901234567890121234567890123456 142 p. 12345678901234567890123456789012123456789012345678901234567890121234567890123456 12345678901234567890123456789012123456789012345678901234567890121234567890123456 12345678901234567890123456789012123456789012345678901234567890121234567890123456 12345678901234567890123456789012123456789012345678901234567890121234567890123456 537 Tillander, Kati. Utilisation of statistics to assess fire risks in buildings. 2004. 224 p. + app. 37 p. 12345678901234567890123456789012123456789012345678901234567890121234567890123456 12345678901234567890123456789012123456789012345678901234567890121234567890123456 12345678901234567890123456789012123456789012345678901234567890121234567890123456 12345678901234567890123456789012123456789012345678901234567890121234567890123456 538 Wallin, Arto. Secure auction for mobile agents. 2004. 102 p. 12345678901234567890123456789012123456789012345678901234567890121234567890123456 12345678901234567890123456789012123456789012345678901234567890121234567890123456 12345678901234567890123456789012123456789012345678901234567890121234567890123456 12345678901234567890123456789012123456789012345678901234567890121234567890123456 539 Kolari, Juha, Laakko, Timo, Hiltunen, Tapio, Ikonen, Veikko, Kulju, Minna, Suihkonen, 12345678901234567890123456789012123456789012345678901234567890121234567890123456 12345678901234567890123456789012123456789012345678901234567890121234567890123456 12345678901234567890123456789012123456789012345678901234567890121234567890123456 Raisa, Toivonen, Santtu & Virtanen, Tytti. Context-Aware Services for Mobile Users. 12345678901234567890123456789012123456789012345678901234567890121234567890123456 12345678901234567890123456789012123456789012345678901234567890121234567890123456 Technology and User Experiences. 2004. 167 p. + app. 3 p. 12345678901234567890123456789012123456789012345678901234567890121234567890123456 12345678901234567890123456789012123456789012345678901234567890121234567890123456 12345678901234567890123456789012123456789012345678901234567890121234567890123456 12345678901234567890123456789012123456789012345678901234567890121234567890123456 540 Villberg, Kirsi, Saarela, Kristina, Tirkkonen, Tiina, Pasanen, Anna-Liisa, Kasanen, Jukka- 12345678901234567890123456789012123456789012345678901234567890121234567890123456 12345678901234567890123456789012123456789012345678901234567890121234567890123456 12345678901234567890123456789012123456789012345678901234567890121234567890123456 Pekka, Pasanen, Pertti, Kalliokoski, Pentti, Mussalo-Rauhamaa, Helena, Malmberg, 12345678901234567890123456789012123456789012345678901234567890121234567890123456 12345678901234567890123456789012123456789012345678901234567890121234567890123456 12345678901234567890123456789012123456789012345678901234567890121234567890123456 Marjatta & Haahtela, Tari. Sisäilman laadun hallinta. 2004. 172 s. + liitt. 20 s. 12345678901234567890123456789012123456789012345678901234567890121234567890123456 12345678901234567890123456789012123456789012345678901234567890121234567890123456 12345678901234567890123456789012123456789012345678901234567890121234567890123456 541 Saloheimo, Anu. Yeast Saccharomyces cerevisiae as a tool in cloning and analysis of 12345678901234567890123456789012123456789012345678901234567890121234567890123456 12345678901234567890123456789012123456789012345678901234567890121234567890123456 12345678901234567890123456789012123456789012345678901234567890121234567890123456 fungal genes. Applications for biomass hydrolysis and utilisation. 2004. 84 p. + app. 12345678901234567890123456789012123456789012345678901234567890121234567890123456 12345678901234567890123456789012123456789012345678901234567890121234567890123456 12345678901234567890123456789012123456789012345678901234567890121234567890123456 52 p. 12345678901234567890123456789012123456789012345678901234567890121234567890123456 12345678901234567890123456789012123456789012345678901234567890121234567890123456 12345678901234567890123456789012123456789012345678901234567890121234567890123456 12345678901234567890123456789012123456789012345678901234567890121234567890123456 542 Pulkkinen, Pekka. Mapping C++ Data Types into a Test Specification Language. 2004. 89 p. + 12345678901234567890123456789012123456789012345678901234567890121234567890123456 12345678901234567890123456789012123456789012345678901234567890121234567890123456 app. 13 p. 12345678901234567890123456789012123456789012345678901234567890121234567890123456 543 Holopainen, Timo P. Electromechanical interaction in rotordynamics of cage induction motors. 2004. 64 p. + app. 81 p. 544 Sademies, Anni. Process Approach to Information Security Metrics in Finnish Industry Arja Miettinen-Oinonen and State Institutions. 2004. 89 p. + app. 2 p. 545 DairyNET - hygiene control in Nordic dairies. Gun Wirtanen & Satu Salo (eds.). 2004. 253 p. + app. 63 p. Trichoderma reesei strains for 547 Hänninen, Saara & Rytkönen, Jorma. Oil transportation and terminal development in the Gulf of Finland. 2004. 141 p. + app. 6 p. production of cellulases for 548 Nevanen, Tarja K. Enantioselective antibody fragments. 2004. 92 p. + app 41 p. 550 Miettinen-Oinonen, Arja. Trichoderma reesei strains for production of cellulases for the the textile industry textile industry.
Load more

Recommended publications
  • Direct Ethanol Production from Cellulose by Consortium Of
    Spec. Matrices 2019; 7:1–19 Research Article Open Access Kazumasa Nomura* and Paul Terwilliger Green Process Synth 2019; 8: 416–420 Self-dual Leonard pairs Yingjie Bu, Bassam Alkotaini, Bipinchandra K. Salunke, Aarti R. Deshmukh, Pathikrit Saha and Beom Soo Kim* https://doi.org/10.1515/spma-2019-0001 Received May 8, 2018; accepted September 22, 2018 Direct ethanol productionAbstract: Let F denote from a eld and cellulose let V denote a vector by space over F with nite positive dimension. Consider a pair A, A∗ of diagonalizable F-linear maps on V, each of which acts on an eigenbasis for the other one in an consortium of Trichodermairreducible tridiagonal fashion. reesei Such a and pair is called Candida a Leonard pair. We consider the self-dual case in which molischiana there exists an automorphism of the endomorphism algebra of V that swaps A and A∗. Such an automorphism is unique, and called the duality A A∗. In the present paper we give a comprehensive description of this ↔ duality. In particular, we display an invertible F-linear map T on V such that the map X TXT− is the duality https://doi.org/10.1515/gps-2019-0009 waste are attractive alternatives to fossil fuels [1]. New → A A∗. We express T as a polynomial in A and A∗. We describe how T acts on ags, decompositions, Received August 13, 2018; accepted October 09,↔ 2018. technologies to convert plant biomass into alternative and 24 bases for V. biofuels, such as bioethanol, are being developed [2]. Abstract: Industrial cellulosic ethanol production is a Fermentation-derived ethanol can be produced from challenge due to the high cost of cellulasesKeywords: for Leonardhydroly- pair, tridiagonal matrix, self-dual sugar, starch, or lignocellulosic biomass.
    [Show full text]
  • Parallel Molecular Evolution of Catalases and Superoxide Dismutases—Focus on Thermophilic Fungal Genomes
    antioxidants Article Parallel Molecular Evolution of Catalases and Superoxide Dismutases—Focus on Thermophilic Fungal Genomes Katarína Chovanová 1, Miroslav Böhmer 2 , Andrej Poljovka 1, Jaroslav Budiš 2, Jana Harichová 1, Tomáš Szemeš 2 and Marcel Zámocký 1,3,* 1 Laboratory for Phylogenomic Ecology, Institute of Molecular Biology, Slovak Academy of Sciences, Dúbravska cesta 21, SK-84551 Bratislava, Slovakia; [email protected] (K.C.); [email protected] (A.P.); [email protected] (J.H.) 2 Department of Molecular Biology, Faculty of Nat. Sciences, Science Park of Comenius University, Comenius University, Ilkoviˇcova8, SK-84104 Bratislava, Slovakia; [email protected] (M.B.); [email protected] (J.B.); [email protected] (T.S.) 3 Department of Chemistry, Institute of Biochemistry, BOKU, University of Natural Resources and Life Sciences, Muthgasse 18, A-1190 Vienna, Austria * Correspondence: [email protected] Received: 24 September 2020; Accepted: 22 October 2020; Published: 27 October 2020 Abstract: Catalases (CAT) and superoxide dismutases (SOD) represent two main groups of enzymatic antioxidants that are present in almost all aerobic organisms and even in certain anaerobes. They are closely interconnected in the catabolism of reactive oxygen species because one product of SOD reaction (hydrogen peroxide) is the main substrate of CAT reaction finally leading to harmless products (i.e., molecular oxygen and water). It is therefore interesting to compare the molecular evolution of corresponding gene families. We have used a phylogenomic approach to elucidate the evolutionary relationships among these two main enzymatic antioxidants with a focus on the genomes of thermophilic fungi. Distinct gene families coding for CuZnSODs, FeMnSODs, and heme catalases are very abundant in thermophilic Ascomycota.
    [Show full text]
  • Trichoderma Genome to Genomics: a Review
    g in Geno nin m i ic M s ta & a P Srivastava et al., J Data Mining Genomics Proteomics 2014, 5:3 D r f o Journal of o t e l DOI: 10.4172/2153-0602.1000162 o a m n r i c u s o J ISSN: 2153-0602 Data Mining in Genomics & Proteomics Review Article Open Access Trichoderma Genome to Genomics: A Review Mukesh Srivastava*, Mohammad Shahid, Sonika Pandey, Anuradha Singh, Vipul Kumar, Shyamji Gupta and Manoj Maurya Biocontrol Laboratory, Department of Plant Pathology, Chandra Shekhar Azad University of Agriculture & Technology, Kanpur, Uttar Pradesh, India Abstract Trichoderma species are widely used in agriculture as biopesticides. These fungi reproduce asexually by production of conidia and chlamydospores and in wild habitats by ascospores. Trichoderma species are well known for their production of enzymes called Cell Wall Degrading Enzymes (CWDEs). All living organisms are made up of genes that code for a protein which performs the particular function. Some genes that play an important role in the biocontrol process are known as the biocontrol genes. These genes send some signals which help in secretion of proteins and enzymes that degrade the plant pathogens. These biocontrol genes can be cloned in huge amounts and can be used on large scale for commercial production. Some Trichoderma genes are also helpful in providing resistance to the biotic and abiotic stresses such as heat, drought and salt .The major biocontrol processes include antibiosis, mycoparasitism and providing plant nutrition. Keywords: Trichoderma; Biocontrol genes; Cell wall degrading have been preserved from this study. No further morphological enzymes differentiation of the anamorphs was attempted by Doi and Doi.
    [Show full text]
  • Thermophilic Fungi: Taxonomy and Biogeography
    Journal of Agricultural Technology Thermophilic Fungi: Taxonomy and Biogeography Raj Kumar Salar1* and K.R. Aneja2 1Department of Biotechnology, Chaudhary Devi Lal University, Sirsa – 125 055, India 2Department of Microbiology, Kurukshetra University, Kurukshetra – 136 119, India Salar, R. K. and Aneja, K.R. (2007) Thermophilic Fungi: Taxonomy and Biogeography. Journal of Agricultural Technology 3(1): 77-107. A critical reappraisal of taxonomic status of known thermophilic fungi indicating their natural occurrence and methods of isolation and culture was undertaken. Altogether forty-two species of thermophilic fungi viz., five belonging to Zygomycetes, twenty-three to Ascomycetes and fourteen to Deuteromycetes (Anamorphic Fungi) are described. The taxa delt with are those most commonly cited in the literature of fundamental and applied work. Latest legal valid names for all the taxa have been used. A key for the identification of thermophilic fungi is given. Data on geographical distribution and habitat for each isolate is also provided. The specimens deposited at IMI bear IMI number/s. The document is a sound footing for future work of indentification and nomenclatural interests. To solve residual problems related to nomenclatural status, further taxonomic work is however needed. Key Words: Biodiversity, ecology, identification key, taxonomic description, status, thermophile Introduction Thermophilic fungi are a small assemblage in eukaryota that have a unique mechanism of growing at elevated temperature extending up to 60 to 62°C. During the last four decades many species of thermophilic fungi sporulating at 45oC have been reported. The species included in this account are only those which are thermophilic in the sense of Cooney and Emerson (1964).
    [Show full text]
  • Genetic Engineering of Fungal Cells-Margo M
    BIOTECHNOLOGY- Vol III - Genetic Engineering of Fungal Cells-Margo M. Moore GENETIC ENGINEERING OF FUNGAL CELLS Margo M. Moore Department of Biological Sciences, Simon Fraser University, Burnaby, Canada Keywords: filamentous fungi, transformation, protoplasting, Agrobacterium, promoter, selectable marker, REMI, transposon, non-homologous end joining, homologous recombination Contents 1. Introduction 1.1. Industrial importance of fungi 1.2. Purpose and range of topics covered 2. Generation of transforming constructs 2.1. Autonomously-replicating plasmids 2.2. Promoters 2.2.1. Constitutive promoters 2.2.2. Inducible promoters 2.3. Selectable markers 2.3.1. Dominant selectable markers 2.3.2. Auxotropic/inducible markers 2.4. Gateway technology 2.5. Fusion PCR and Ligation PCR 3. Transformation methods 3.1. Protoplast formation and CaCl2/ PEG 3.2. Electroporation 3.3. Agrobacterium-mediated Ti plasmid 3.4. Biolistics 3.5. Homo- versus heterokaryotic selection 4. Gene disruption and gene replacement 4.1. Targetted gene disruption 4.1.1. Ectopic and homologous recombination 4.1.2. Strains deficient in non-homologous end joining (NHEJ) 4.1.3. AMT and homologous recombination 4.1.4. RNA interference 4.2. RandomUNESCO gene disruption – EOLSS 4.2.1. Restriction enzyme-mediated integration (REMI) 4.2.2. T-DNA taggingSAMPLE using Agrobacterium-mediated CHAPTERS transformation (AMT) 4.2.3. Transposon mutagenesis & TAGKO 5. Concluding statement Glossary Bibliography Biographical Sketch Summary Filamentous fungi have myriad industrial applications that benefit mankind while at the ©Encyclopedia of Life Support Systems (EOLSS) BIOTECHNOLOGY- Vol III - Genetic Engineering of Fungal Cells-Margo M. Moore same time, fungal diseases of plants cause significant economic losses.
    [Show full text]
  • Trichoderma: the “Secrets” of a Multitalented Biocontrol Agent
    plants Review Trichoderma: The “Secrets” of a Multitalented Biocontrol Agent 1, 1, 2 3 Monika Sood y, Dhriti Kapoor y, Vipul Kumar , Mohamed S. Sheteiwy , Muthusamy Ramakrishnan 4 , Marco Landi 5,6,* , Fabrizio Araniti 7 and Anket Sharma 4,* 1 School of Bioengineering and Biosciences, Lovely Professional University, Jalandhar-Delhi G.T. Road (NH-1), Phagwara, Punjab 144411, India; [email protected] (M.S.); [email protected] (D.K.) 2 School of Agriculture, Lovely Professional University, Delhi-Jalandhar Highway, Phagwara, Punjab 144411, India; [email protected] 3 Department of Agronomy, Faculty of Agriculture, Mansoura University, Mansoura 35516, Egypt; [email protected] 4 State Key Laboratory of Subtropical Silviculture, Zhejiang A&F University, Hangzhou 311300, China; [email protected] 5 Department of Agriculture, University of Pisa, I-56124 Pisa, Italy 6 CIRSEC, Centre for Climatic Change Impact, University of Pisa, Via del Borghetto 80, I-56124 Pisa, Italy 7 Dipartimento AGRARIA, Università Mediterranea di Reggio Calabria, Località Feo di Vito, SNC I-89124 Reggio Calabria, Italy; [email protected] * Correspondence: [email protected] (M.L.); [email protected] (A.S.) Authors contributed equal. y Received: 25 May 2020; Accepted: 16 June 2020; Published: 18 June 2020 Abstract: The plant-Trichoderma-pathogen triangle is a complicated web of numerous processes. Trichoderma spp. are avirulent opportunistic plant symbionts. In addition to being successful plant symbiotic organisms, Trichoderma spp. also behave as a low cost, effective and ecofriendly biocontrol agent. They can set themselves up in various patho-systems, have minimal impact on the soil equilibrium and do not impair useful organisms that contribute to the control of pathogens.
    [Show full text]
  • A Novel Application Potential of GH6 Cellobiohydrolase Ctcel6 From
    INTERNATIONAL JOURNAL OF AGRICULTURE & BIOLOGY ISSN Print: 1560–8530; ISSN Online: 1814–9596 16–768/2017/19–2–355–362 DOI: 10.17957/IJAB/15.0290 http://www.fspublishers.org Full Length Article A Novel Application Potential of GH6 Cellobiohydrolase CtCel6 from Thermophilic Chaetomium thermophilum for Gene Cloning, Heterologous Expression and Biological Characterization Qinzheng Zhou, Jianchao Jia, Peng Ji and Chao Han* Department of Mycology, Shandong Agricultural University, Taian, Shandong 271018, China *For correspondence: [email protected] Abstract Chaetomium thermophilum is a thermophilic fungus expressed a series of glycoside hydrolases. Genome sequence analysis of C. thermophilium revealed that ctcel6 gene encoded a putative cellobiohydrolase which composed of 397 amino acid residues including a predicted signal peptide sequence. Ctcel6 gene was cloned, heterologously expressed in Pichia pastoris and purified by Ni2+ affinity chromatography. Sequence alignment indicated that CtCel6 enzyme belonged to glycoside hydrolase family 6 (GH6) and the molecular mass of purified recombinant enzyme CtCel6 was 42 kDa by SDS-PAGE analysis. Characterization of recombinant CtCel6 exhibited high hydrolysis activity and excellent thermostability. The optimum reaction temperature and pH was 70oC and pH 5, respectively. The bivalent metallic cations Mg2+ and Ca2+ significantly enhanced the activity of CtCel6. The specific activity of CtCel6 enzyme was 1.27 U/mg and Km value was 0.38 mM on β-D- glucan. The substrate specificity and hydrolysis products insisted that CtCel6 was an exo-/endo-type cellobiohydrolase. The biochemical properties of recombinant CtCel6 made it potentially effective for bioconversion of biomass and had tremendous potential in industrial applications such as enzyme preparation industry and feed processing industry.
    [Show full text]
  • Screening Assessment of Trichoderma Reesei Strain ATCC 74252
    Screening assessment of trichoderma reesei strain ATCC 74252 Environment and Climate change Canada Health Canada February 2018 Cat. No.: En14-318/2018E-PDF ISBN 978-0-660-25249-0 Information contained in this publication or product may be reproduced, in part or in whole, and by any means, for personal or public non-commercial purposes, without charge or further permission, unless otherwise specified. You are asked to: • Exercise due diligence in ensuring the accuracy of the materials reproduced; • Indicate both the complete title of the materials reproduced, as well as the author organization; and • Indicate that the reproduction is a copy of an official work that is published by the Government of Canada and that the reproduction has not been produced in affiliation with or with the endorsement of the Government of Canada. Commercial reproduction and distribution is prohibited except with written permission from the author. For more information, please contact Environment and Climate Change Canada’s Inquiry Centre at 1-800-668-6767 (in Canada only) or 819-997-2800 or email to [email protected]. © Her Majesty the Queen in Right of Canada, represented by the Minister of the Environment and Climate Change, 2018. Aussi disponible en français ii Synopsis Pursuant to paragraph 74(b) of the Canadian Environmental Protection Act, 1999 (CEPA), the Minister of the Environment and the Minister of Health have conducted a screening assessment of Trichoderma reesei ATCC1 74252. Trichoderma reesei (T. reesei) strain ATCC 74252 is a fungus that has characteristics in common with other species of the genus Trichoderma and other strains of the same species.
    [Show full text]
  • GRAS Notice 756, Endo-1,4-Beta-Glucanase from Trichoderma Reesei
    GRAS Notice (GRN) No. 756 https://www.fda.gov/Food/IngredientsPackagingLabeling/GRAS/NoticeInventory/default.htm AB Enzymes AB Enzymes GmbH - Feldbergstrasse 78, D-64293 Darmstadt January 5, 2018 Office of Food Additive Safety (HFS-255), Center for Food Safety and Applied Nutrition, Food and Drug Administration, 5100 Paint Branch Parkway, College Park, MD 20740. RE: GR GRAS Notification for an endo-1,4-13- glucanase from a genetically modified Trichoderma reesei AB Enzymes GmbH, we are submitting for FDA review, Form 3667, one paper copy, and the enclosed CD, free of viruses, containing a GRAS notification for endo-1,4-13- glucanase. The attached documentation contains the specific information that addresses the safe human food uses for the subject notified substances as discussed in GRAS final rule, 21 CFR Part 170.30 (a)(b), subpart E. Please contact the undersigned by telephone or email if you have any questions or additional information is required. We look forward to your feedback. Candice Cryne Regulatory Affairs Manager 1 647-919-3964 Candi [email protected] Form Approved: 0MB No. 0910-0342 ; Expiration Date: 09/30/2019 (See last page for 0MB Statement) FDA USE ONLY GRN NUMBER DATE OF,~ CEIPT ~(!)t:) "76@ I '2..11-J 2o g DEPARTMENT OF HEAL TH AND HUMAN SERVICES ESTIMATED DAILY INTAKE INTENDED USE FOR INTERNET Food and Drug Administration GENERALLY RECOGNIZED AS SAFE - NAME FOR INTERNET (GRAS) NOTICE (Subpart E of Part 170) KEYWORDS Transmit completed form and attachments electronically via the Electronic Submission Gateway (see Instructions); OR Transmit completed form and attachments in paper format or on physical media to: Office of Food Additive Safety (HFS-200), Center for Food Safety and Applied Nutrition, Food and Drug Administration,5001 Campus Drive, College Park, MD 20740-3835.
    [Show full text]
  • Cellulases Production by a Trichoderma Sp. Using Food Manufacturing Wastes
    applied sciences Article Cellulases Production by a Trichoderma sp. Using Food Manufacturing Wastes Felipe Gordillo-Fuenzalida 1, Alex Echeverria-Vega 2 , Sara Cuadros-Orellana 1, Claudia Faundez 1, Thilo Kähne 3 and Rodrigo Morales-Vera 1,4,* 1 Centro de Biotecnología de los Recursos Naturales (CENBIO), Facultad de Ciencias Agrarias y Forestales, Universidad Católica del Maule, Avda. San Miguel 3605, Talca 3480112, Chile 2 Centro de Investigación en Estudios Avanzados del Maule (CIEAM), Vicerrectoría de Investigación y Postgrado, Universidad Católica del Maule, Avda. San Miguel 3605, Talca 3480112, Chile 3 Institute of Experimental Internal Medicine, Otto-von-Guericke University, Magdeburg 39120, Germany 4 Facultad de Ingeniería, Ciencias y Tecnología, Universidad Bernardo O’Higgins, Santiago 8370993, Chile * Correspondence: [email protected]; Tel.: +56-71-2203505 Received: 9 August 2019; Accepted: 16 October 2019; Published: 18 October 2019 Abstract: The cost of cellulase enzymes is a main contributor to the operational cost of a biorefinery producing ethanol from lignocellulosic material. Therefore, onsite production of enzymes using low-value substrates might be an option to make a bio-based facility more economical, while improving environmental sustainability. Food manufacturing wastes (FMWs), such as olive mill solids, tomato pomace, and grape pomace, are some of the main wastes produced by the food industry in Chile. FMWs are mostly composed of lignocellulosic material, which is primarily made of cellulose. A fungal strain obtained from olive stones was identified as a Trichoderma sp. and characterized by molecular and morphological techniques. This strain was able to grow on three FMWs in both liquid and solid cultures. In liquid cultures, cellulase and β-glucosidase activities from the culture supernatants were quantified.
    [Show full text]
  • Sexual Development in the Industrial Workhorse Trichoderma Reesei
    Sexual development in the industrial workhorse Trichoderma reesei Verena Seidl, Christian Seibel, Christian P. Kubicek, and Monika Schmoll1 Research Area Gene Technology and Applied Biochemistry, Institute of Chemical Engineering, Vienna University of Technology, Getreidemarkt 9/166–5, 1060 Vienna, Austria Edited by Arnold L. Demain, Drew University, Madison, NJ, and approved June 30, 2009 (received for review May 5, 2009) Filamentous fungi are indispensable biotechnological tools for the ings, as have been established for the model fungi Aspergillus production of organic chemicals, enzymes, and antibiotics. Most of nidulans or Neurospora crassa, are unavailable. the strains used for industrial applications have been—and still The genus Trichoderma/Hypocrea contains several hundred are—screened and improved by classical mutagenesis. Sexual species, some of which only occur as teleomorphs, i.e., in their crossing approaches would yield considerable advantages for sexual form, whereas others have so far only been observed as research and industrial strain improvement, but interestingly, asexually propagating anamorphs (5). In the last decade, the use industrially applied filamentous fungal species have so far been of DNA-based molecular phylogenetic approaches has suc- considered to be largely asexual. This is also true for the ascomy- ceeded in the identification of anamorph-teleomorph relation- cete Trichoderma reesei (anamorph of Hypocrea jecorina), which is ships for several fungi (including Trichoderma spp.) that were so used for production of cellulolytic and hemicellulolytic enzymes. In far believed to occur only in an asexual form. However, only few this study, we report that T. reesei QM6a has a MAT1-2 mating type of these could be mated under laboratory conditions (6).
    [Show full text]
  • Genome Sequence of Trichoderma Lixii MUT3171, a Promising Strain for Mycoremediation of PAH-Contaminated Sites
    microorganisms Article Genome Sequence of Trichoderma lixii MUT3171, A Promising Strain for Mycoremediation of PAH-Contaminated Sites Francesco Venice 1, Domenico Davolos 2, Federica Spina 3 , Anna Poli 3, Valeria Paola Prigione 3, Giovanna Cristina Varese 3,* and Stefano Ghignone 1 1 Institute for Sustainable Plant Protection (IPSP)–SS Turin—National Research Council (CNR), Viale Mattioli 25, 10125 Turin, Italy; [email protected] (F.V.); [email protected] (S.G.) 2 Department of Technological Innovations and Safety of Plants, Products and Anthropic Settlements (DIT), INAIL, Research Area, Via R. Ferruzzi 38/40, 00143 Rome, Italy; [email protected] 3 Department of Life Sciences and System Biology, University of Turin, Viale Mattioli 25, 10125 Turin, Italy; [email protected] (F.S.); [email protected] (A.P.); [email protected] (V.P.P.) * Correspondence: [email protected]; Tel.: +39-011-670-5984 Received: 14 July 2020; Accepted: 17 August 2020; Published: 20 August 2020 Abstract: Mono- and polycyclic aromatic hydrocarbons (PAHs) are widespread and recalcitrant pollutants that threaten both environmental and human health. By exploiting the powerful enzymatic machinery of fungi, mycoremediation in contaminated sites aims at removing a wide range of pollutants in a cost-efficient and environmentally friendly manner. Next-generation sequencing (NGS) techniques are powerful tools for understanding the molecular basis of biotransformation of PAHs by selected fungal strains, allowing genome mining to identify genetic features of biotechnological value. Trichoderma lixii MUT3171, isolated from a historically PAH-contaminated soil in Italy, can grow on phenanthrene, as a sole carbon source.
    [Show full text]