UC San Diego UC San Diego Previously Published Works Title Comparative genomic analysis of integral membrane transport proteins in ciliates. Permalink https://escholarship.org/uc/item/3g98s19z Journal The Journal of eukaryotic microbiology, 62(2) ISSN 1066-5234 Authors Kumar, Ujjwal Saier, Milton H Publication Date 2015-03-01 DOI 10.1111/jeu.12156 Peer reviewed eScholarship.org Powered by the California Digital Library University of California The Journal of Published by the International Society of Eukaryotic Microbiology Protistologists Journal of Eukaryotic Microbiology ISSN 1066-5234 ORIGINAL ARTICLE Comparative Genomic Analysis of Integral Membrane Transport Proteins in Ciliates Ujjwal Kumar & Milton H. Saier Jr Division of Biological Sciences, University of California at San Diego, La Jolla, California Keywords ABSTRACT Channels; evolution; genome analyses; secondary carriers. Integral membrane transport proteins homologous to those found in the Transporter Classification Database (TCDB; www.tcdb.org) were identified and Correspondence bioinformatically characterized by transporter class, family, and substrate speci- M. H. Saier Jr, Division of Biological ficity in three ciliates, Paramecium tetraurelia (Para), Tetrahymena thermophila Sciences, University of California at San (Tetra), and Ichthyophthirius multifiliis (Ich). In these three organisms, 1,326 of Diego, La Jolla, CA 92093-0116, USA 39,600 proteins (3.4%), 1,017 of 24,800 proteins (4.2%), and 504 out of 8,100 Telephone number: +858-534-4084; proteins (6.2%) integral membrane transport proteins were identified, respec- FAX number: +858-534-7108; tively. Thus, an inverse relationship was observed between the % transporters e-mail:
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