Post-Genomic Regulation Dictates Venom Profiles of Medically
bioRxiv preprint doi: https://doi.org/10.1101/2020.12.15.422536; this version posted December 16, 2020. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under aCC-BY-ND 4.0 International license. 1 A wolf in another wolf’s clothing: Post-genomic regulation dictates 2 venom profiles of medically-important cryptic kraits in India 3 4 Kartik Sunagar1@†, Suyog Khochare1†, R R Senji Laxme1, Saurabh Attarde1, Paulomi 5 Dam1, Vivek Suranse1, Anil Khaire2, Gerard Martin3 and Ashok Captain4 6 7 1. Evolutionary Venomics Lab. Centre for Ecological Sciences, Indian Institute of 8 Science, Bangalore 560012, Karnataka, India. 9 2. Indian Herpetological Society, 7/47, Pune Satara Road, Pune 411009, 10 Maharashtra, India. 11 3. The Liana Trust. Survey #1418/1419 Rathnapuri, Hunsur 571189, Karnataka, 12 India. 13 4. 3/1 Boat Club Road, Pune 411001, Maharashtra, India. 14 15 † Equal contribution 16 @Corresponding author Page | 1 bioRxiv preprint doi: https://doi.org/10.1101/2020.12.15.422536; this version posted December 16, 2020. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under aCC-BY-ND 4.0 International license. 17 Abstract 18 The Common Krait (Bungarus caeruleus) shares a distribution range with many other 19 ‘phenotypically-similar’ kraits across the Indian subcontinent. Despite several reports of 20 fatal envenoming by other Bungarus species, commercial Indian antivenoms are only 21 manufactured against B.
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