The Jihe Expressway in Shandong Province
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Malaria Control and Prevention Towards Elimination: Data from an Eleven-Year Surveillance in Shandong Province, China
Kong et al. Malar J (2017) 16:55 DOI 10.1186/s12936-017-1708-0 Malaria Journal RESEARCH Open Access Malaria control and prevention towards elimination: data from an eleven‑year surveillance in Shandong Province, China Xiangli Kong1†, Xin Liu1†, Hong Tu3†, Yan Xu1, Jianbing Niu2, Yongbin Wang1, Changlei Zhao1, Jingxuan Kou1 and Jun Feng3* Abstract Background: Shandong Province experienced a declining malaria trend of local-acquired transmission, but the increasing imported malaria remains a challenge. Therefore, understanding the epidemiological characteristics of malaria and the control and elimination strategy and interventions is needed for better planning to achieve the over- all elimination goal in Shandong Province. Methods: A retrospective study was conducted and all individual cases from a web-based reporting system were reviewed and analysed to explore malaria-endemic characteristics in Shandong from 2005 to 2015. Annual malaria incidence reported in 2005–2015 were geo-coded and matched to the county-level. Spatial cluster analysis was performed to evaluate any identified spatial disease clusters for statistical significance. The space–time cluster was detected with high rates through the retrospective space–time analysis scanning using the discrete Poisson model. Results: The overall malaria incidence decreased to a low level during 2005–2015. In total, 1564 confirmed malaria cases were reported, 27.1% of which (n 424) were indigenous cases. Most of the indigenous case (n 339, 80.0%) occurred from June to October. However,= the number and scale of imported cases have been increased= but no significant difference was observed during months. Shandong is endemic for both Plasmodium vivax (n 730) and Plasmodium falciparum (n 674). -
Emperor's River: China's Grand Canal – Philipp Scholz Rittermann July 1
Emperor’s River: China’s Grand Canal – Philipp Scholz Rittermann July 1 – November 30, 2014 Harn Museum of Art -- Rubin Gallery Introduction In 2009 and 2010, photographer Philipp Scholz Rittermann traveled along China’s Grand Canal to capture the country’s booming economy, and rapidly changing landscape and social structure. Rittermann’s photographic interests are largely focused on the built environment, and the way people and the planet are transformed by it. He traveled to China first as an invited artist and then on succeeding trips to document this massive waterway. Having mastered, in previous projects, the digital panorama—a format hungry for information—he found his ideal subject in the People’s Republic of China. The number of bridges, boats, scooters, railways, and the subject of the series itself, the Grand Canal, speaks to Rittermann’s fascination with passage. This material manifestation of movement becomes symbolic of our collective human journey in the 21st century. Accelerated passage and progress are the means by which this particular culture, China, and subsequently the world, plunges headlong into the future. Rittermann wants to momentarily arrest these unprecedented changes to reflect on their ramifications. As we voyage out of one century into another, his photographs become lyrical topographical maps from which to chart the course of a brave new world. — Carol McCusker, Curator About the Artist & Series To make his photographs, Philipp Rittermann handholds a digital camera, panning across a scene, making exposures every few seconds, anticipating what is about to happen in each frame. The specific needs of each frame (light, perspective, focal separation) must be understood in a fraction of a second while shooting. -
Elevated Microrna-145 Inhibits the Development of Oral Squamous Cell Carcinoma Through Inactivating ERK/MAPK Signaling Pathway by Down-Regulating
Bioscience Reports (2019) 39 BSR20182214 https://doi.org/10.1042/BSR20182214 Research Article Elevated microRNA-145 inhibits the development of oral squamous cell carcinoma through inactivating ERK/MAPK signaling pathway by down-regulating HOXA1 Downloaded from http://portlandpress.com/bioscirep/article-pdf/39/6/BSR20182214/846268/bsr-2018-2214.pdf by guest on 01 October 2021 Junhai Ding1,*, Dubin Sun2,* and Pengfeng Xie3 1Department of Stomatology, Affiliated Hospital of Jining Medical University, Jining 272100, P.R. China; 2Department of Stomatology, Zoucheng People’s Hospital, Zoucheng 273500, P.R. China; 3Special Functions Section, Jinan Stomatological Hospital, Jinan 250001, P.R. China Correspondence: Pengfeng Xie ([email protected]) Background: Oral cancer is one of the most frequent solid cancers worldwide, and oral squamous cell carcinoma (OSCC) constitutes approximately 90% of oral cancers. The dis- covery of reliable prognostic indicators would be a potential strategy for OSCC treatment. In the present study, we aim to explore the underlying mechanism by which microRNA-145 (miR-145) affected OSCC. Methods: Forty-eight patients diagnosed with OSCC were en- rolled to obtain the OSCC tissues and adjacent normal tissues. The targeting relationship between miR-145 and Homeobox A1 (HOXA1) was verified. In order to assess the effects of miR-145 in OSCC and the detailed regulatory mechanism, the SCC-9 cell line was adopted, in which expression of miR-145 and HOXA1 were altered by transfection. Then, a series of in vitro and in vivo experiments were performed to evaluate the cell viability, migration, in- vasion, and tumor growth. Results: miR-145 was poorly expressed and HOXA1 was highly expressed in OSCC. -
Original Article the Improvement Strategies of Psychological
Int J Clin Exp Med 2019;12(10):12257-12263 www.ijcem.com /ISSN:1940-5901/IJCEM0099360 Original Article The improvement strategies of psychological intervention nursing on the anxiety and living quality of patients with gynecologic malignancies during postoperative chemotherapy Shurong Guan1*, Cuihua Li2*, Jiping Ge3 1Department of Oncology, Yantai Yuhuangding Hospital, Yantai, Shandong, China; 2Department of Nursing, Yantai Yantaishan Hospital, Yantai, Shandong, China; 3No.3 Oncology Department, Tengzhou Central People’s Hospital, Tengzhou, Zaozhuang, Shandong, China. *Equal contributors and co-first authors. Received July 7, 2019; Accepted September 4, 2019; Epub October 15, 2019; Published October 30, 2019 Abstract: Objective: To explore the effect of psychological intervention on the anxiety and living quality of patients with gynecologic malignancies during postoperative chemotherapy. Methods: A total of 100 patients with gyneco- logic malignancies admitted to our hospital were selected as the study subjects. They were randomly included in study group and received routine nursing combined with psychological intervention (n=50), but the control group received only routine nursing (n=50). Self-rating depression scale (SDS) and self-rating anxiety scale (SAS) scores were compared before treatment (T0), 1 week after treatment (T1), 1 month after treatment (T2), and 2 months after treatment (T3). The heart rates of the two groups were recorded. After the treatment, a nursing satisfaction survey was performed among the patients. A 5-year prognostic follow-up and the 5-year overall survival rates of the two groups were recorded. Results: At T1, T2 and T3, the SDS and SAS scores of the study group were lower than those of the control group (P < 0.001). -
New Public Service Mode in Conventional Agricultural Areas: in the Case of Heze in Shandong Province
NEW PUBLIC SERVICE MODE IN CONVENTIONAL AGRICULTURAL AREAS: IN THE CASE OF HEZE IN SHANDONG PROVINCE UBC School of Community Regional Planning Mengying Li April 20, 2018 TABLE OF CONTENTS NEW PUBLIC SERVICE MODE IN Mode 7 CONVENTIONAL AGRICULTURAL AREAS: 4 RECOMMENDATIONS 8 IN THE CASE OF HEZE IN SHANDONG PROVINCE 1 4.1 Basic Public Service 8 TABLE OF CONTENTS 2 4.1.1 Major Towns Selection 9 EXECUTIVE SUMMARY 3 4.1.2 Basic Public Service Mode 10 1. CONTEXT 1 4.2 Developing Public Service 12 1.1 background 1 5. REFERENCE 13 1.2 Study Site (Client) 2 6. APPENDIX 14 2. RESEARCH QUESTIONS AND METHODS 3 Major town selections 14 2.1 Research Methods 3 2.1.1 Best Practice and Literature Review 3 2.2.2 Quantitative and Qualitative Analysis 3 2.2.3 Public Engagement with Stakeholders 3 3. ANALYSIS 4 3.1 principles 5 3.2 Framework of the Basic Public Service Mode 6 3.2.1 Vertical Structure of the New Mode 6 3.2.2 Horizontal Structure of the New Mode 6 3.3 Framework of the developing Service 2 EXECUTIVE SUMMARY Heze City faces some challenges in the This data-driven study offers Proper public service recommendations on how the process of urbanization: low level of urbanization, migration-urbanization principles: Heze City can have proper public phenomenon, and improper public service service mode to meet residents’ mode. Principle 1: A proper public service needs and local development. METHOD facilities mode can match with the The author used three methods including spatial pattern of urbanization and best practice and literature review, help to redistribute population, and BACKGROUND quantitative and qualitative analysis, and improve equity of public service public engagement with stakeholders, to During the new era of “13th Five-year”, China develp new public service mode. -
Federal Register/Vol. 83, No. 221/Thursday, November 15, 2018
Federal Register / Vol. 83, No. 221 / Thursday, November 15, 2018 / Notices 57421 with regard to this program, which had Public Comment DEPARTMENT OF COMMERCE the lowest rate in the Preliminary Determination among the programs Case briefs or other written comments International Trade Administration may be submitted to the Assistant alleged to be inconsistent with the SCM [A–570–073] Agreement. In so doing, we intend to Secretary for Enforcement and limit the corresponding offset to the Compliance no later than seven days Antidumping Duty Investigation of dumping margin (if one is found) in the after the date on which the last Common Alloy Aluminum Sheet From companion antidumping duty verification report is issued in this the People’s Republic of China: investigation, which best fulfills our investigation. Rebuttal briefs, limited to Affirmative Final Determination of statutory mandate ‘‘to ensure that the issues raised in case briefs, may be Sales at Less-Than-Fair Value party does not obtain a more favorable submitted no later than five days after result by failing to cooperate than if it the deadline date for case briefs.20 AGENCY: Enforcement and Compliance, had cooperated fully,’’ 18 and induce Pursuant to 19 CFR 351.309(c)(2) and International Trade Administration, future cooperation by companies in (d)(2), parties who submit case briefs or Department of Commerce. investigations where the petitioners rebuttal briefs in this investigation are SUMMARY: The Department of Commerce allege the existence of programs encouraged to submit with each (Commerce) determines that common potentially inconsistent with the SCM argument: (1) A statement of the issue; alloy aluminum sheet (common alloy Agreement. -
UAV Lidar Point Cloud Segmentation of a Stack
1 UAV LiDAR Point Cloud Segmentation of A Stack Interchange with Deep Neural Networks Weikai Tan, Student Member, IEEE, Dedong Zhang, Lingfei Ma, Ying Li, Lanying Wang, and Jonathan Li, Senior Member, IEEE Abstract—Stack interchanges are essential components of capturing the complicated structure of interchanges due to transportation systems. Mobile laser scanning (MLS) systems limitations of flying altitudes or road surfaces [4]. Unmanned have been widely used in road infrastructure mapping, but accu- aerial vehicle (UAV) is a thriving platform for various sensors, rate mapping of complicated multi-layer stack interchanges are still challenging. This study examined the point clouds collected including Light Detection and Ranging (LiDAR) systems, by a new Unmanned Aerial Vehicle (UAV) Light Detection and with the flexibility of data collection. However, there are Ranging (LiDAR) system to perform the semantic segmentation more uncertainties in point clouds collected by UAV systems, task of a stack interchange. An end-to-end supervised 3D deep such as point registration and calibration, due to less stable learning framework was proposed to classify the point clouds. moving positions than aeroplanes and cars. To capture features The proposed method has proven to capture 3D features in complicated interchange scenarios with stacked convolution and from the massive amounts of unordered and unstructured the result achieved over 93% classification accuracy. In addition, point clouds, deep learning methods have outperformed con- the new low-cost semi-solid-state LiDAR sensor Livox Mid- ventional threshold-based methods and methods using hand- 40 featuring a incommensurable rosette scanning pattern has crafted features in recent years [5]. -
Circrna LRIG3 Knockdown Inhibits Hepatocellular Carcinoma Progression by Regulating Mir-223-3P and MAPK/ERK Pathway
CircRNA LRIG3 knockdown inhibits hepatocellular carcinoma progression by regulating miR-223-3p and MAPK/ERK pathway Type Research paper Keywords hepatocellular carcinoma, miR-223-3p, circ_LRIG3, MAP2K6, MAPK/ERK pathway Abstract Introduction Emerging evidence suggests that circular RNAs (circRNAs) play critical roles in tumorigenesis. However, the roles and molecular mechanisms of circRNA leucine-rich repeat immunoglobulin domain-containing protein 3 (circ_LRIG3) in hepatocellular carcinoma (HCC) has not been investigated. Material and methods The expression levels of circ_LRIG3, miR-223-3p, and mitogen-activated protein kinase kinase 6 (MAP2K6) were determined by qRT-PCR. Flow cytometry was applied to determine the cell cycle distribution and apoptosis. Cell proliferation, migration and invasion were assessed by MTT, colony formation, and transwell assays. Western blot assay was employed to measure the protein levels of the snail, E-cadherin, MAP2K6, mitogen-activated protein kinase (MAPK), phospho-MAPK (p- MAPK), extracellular signal-regulated kinases (ERKs), and phospho-ERKs (p- ERKs). The relationship between miR-223-3p and circ_LRIG3 or MAP2K6 was predicted by bioinformatics tools and verified by dual-luciferase reporter assay. A xenograft tumor model was established to confirm the functions of circ_LRIG3 in vivo. Results Preprint Circ_LRIG3 and MAP2K6 expression were enhanced while miR-223-3p abundance was reduced in HCC tissues and cells. Knockdown of circ_LRIG3 inhibited cell proliferation, metastasis, and increasing apoptosis. MiR-223-3p was a target of circ_LRIG3, and its downregulation reversed the inhibitory effect of circ_LRIG3 knockdown on the progression of HCC cells. Moreover, MAP2K6 could bind to miR-223-3p, and MAP2K6 upregulation also abolished the suppressive impact of circ_LRIG3 interference on progression of HCC cells. -
(LTA) Evaluation of the Baton Rouge Urban Renewal and Mobility Plan
Louisiana Transportation Authority (LTA) Evaluation of the Baton Rouge Urban Renewal and Mobility Plan (BUMP) to Develop the Project as a Public Private Partnership (P3) October 20, 2015 – Final (With Redactions) TABLE OF CONTENTS EXECUTIVE SUMMARY ............................................................................................................ 1 Proposal Overview .................................................................................................................... 1 Construction Cost...................................................................................................................... 1 Tolling ....................................................................................................................................... 1 Traffic and Revenue (T&R) ...................................................................................................... 2 Feasibility .................................................................................................................................. 2 Findings..................................................................................................................................... 3 1.0 CHAPTER ONE – State & Federal Legislation Summary ................................................... 4 1.1 Louisiana State Legislation .............................................................................................. 4 1.2 Federal Legislation .......................................................................................................... -
Hydrochemical Characteristics and Formation Mechanism of Groundwater in West Zoucheng City, Shandong Province, China
Hydrochemical Characteristics and Formation Mechanism of Groundwater in West Zoucheng City, Shandong Province, China Hao Chen North-West University Jiading Wang ( [email protected] ) Northwest University Fei Zhang Shandong Provincial Lunan Geology and Exploration Institute Yaxing Zhou Shandong Provincial Lunan Geology and Exploration Institute Chunying Xia Shandong Provincial Lunan Geology and Exploration Institute Wenliang Zhang Shandong Provincial Lunan Geology and Exploration Institute Xianzhou Meng Shandong Provincial Lunan Geology and Exploration Institute Jia Meng Shandong Provincial Lunan Geology and Exploration Institute Research Article Keywords: Karst groundwater, Hydrochemical characteristics, Formation mechanism, Principal component analysis, Zoucheng city Posted Date: July 20th, 2021 DOI: https://doi.org/10.21203/rs.3.rs-722323/v1 License: This work is licensed under a Creative Commons Attribution 4.0 International License. Read Full License Page 1/16 Abstract The groundwater in the western part of Zoucheng is an important water source for domestic, industrial and agricultural use in Zoucheng. Understanding its hydrochemical characteristics and formation mechanism is of great signicance to the sustainable development and utilization of groundwater. In this study, 36 water samples were collected during wet and dry seasons, and the hydrochemical components K+, Na+, Ca2+, Mg2+, Cl-, 2- - - - SO4 , HCO3 , NO3 , F , TH and TDS were analyzed. Graphic method, correlation analysis and principal component analysis were applied to explore the hydrochemical characteristics and evolution mechanism of groundwater in the study area. The results show that: (1) The orders of the anion and 2+ + 2+ + - 2- - - - cation concentrations of karst groundwater and pore groundwater are Ca >Na >Mg >K and HCO3 >SO4 >Cl >NO3 >F . -
Federal Register/Vol. 81, No. 141/Friday, July 22, 2016/Notices
47754 Federal Register / Vol. 81, No. 141 / Friday, July 22, 2016 / Notices Fees are set taking into account the whose data they process, which would (‘‘Department’’) pursuant to the CIT’s operational costs borne by ITA to use more government resources remand of the final determination in the administer and supervise the Privacy dedicated to administering and antidumping duty investigation on Shield program. The Privacy Shield overseeing Privacy Shield. For example, certain new pneumatic off-the-road tires program will require a significant if a company holds more data it could (‘‘OTR tires’’) from the People’s commitment of resources and staff. The reasonably produce more questions and Republic of China (‘‘PRC’’). This case Privacy Shield Framework includes complaints from consumers and the arises out of the Department’s final commitments from ITA to: European Union’s Data Protection determination in the antidumping duty • Maintain a Privacy Shield Web site; Authorities (DPAs). ITA has committed (‘‘AD’’) investigation on OTR tires from • verify self-certification to facilitating the resolution of the PRC. See Certain New Pneumatic requirements submitted by individual complaints and to Off-The-Road-Tires from the People’s organizations to participate in the communicating with the FTC and the Republic of China: Final Affirmative program; DPAs regarding consumer complaints. Determination of Sales at Less Than Fair • expand efforts to follow up with Lastly, the fee increases between the Value and Partial Affirmative organizations that have been removed tiers are based in part on projected Determination of Critical from the Privacy Shield List; program costs and estimated Circumstances, 73 FR 40485 (July 15, • search for and address false claims participation levels among companies 2008), as amended by Certain New of participation; • within each tier. -
Chinacoalchem
ChinaCoalChem Monthly Report Issue May. 2019 Copyright 2019 All Rights Reserved. ChinaCoalChem Issue May. 2019 Table of Contents Insight China ................................................................................................................... 4 To analyze the competitive advantages of various material routes for fuel ethanol from six dimensions .............................................................................................................. 4 Could fuel ethanol meet the demand of 10MT in 2020? 6MTA total capacity is closely promoted ....................................................................................................................... 6 Development of China's polybutene industry ............................................................... 7 Policies & Markets ......................................................................................................... 9 Comprehensive Analysis of the Latest Policy Trends in Fuel Ethanol and Ethanol Gasoline ........................................................................................................................ 9 Companies & Projects ................................................................................................... 9 Baofeng Energy Succeeded in SEC A-Stock Listing ................................................... 9 BG Ordos Started Field Construction of 4bnm3/a SNG Project ................................ 10 Datang Duolun Project Created New Monthly Methanol Output Record in Apr ........ 10 Danhua to Acquire &