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MONITORAMENTO EM BIOTECNOLOGIA Desenvolvimento Científico E Tecnológico Foco – Brasil

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MONITORAMENTO EM BIOTECNOLOGIA Desenvolvimento Científico E Tecnológico Foco – Brasil MONITORAMENTO EM BIOTECNOLOGIA Desenvolvimento científico e tecnológico Foco – Brasil 2° Relatório Executor: Sistema de Informação sobre a Indústria Química (SIQUIM) Escola de Química (EQ) Universidade Federal do Rio de Janeiro (UFRJ) Janeiro / 2005 EQUIPE: Coordenação Geral: Profª Dra. Adelaide Antunes Coordenação Técnica: Dra. Claudia Canongia Pesquisadores: Simone Alencar Engenheira Química, Doutoranda EQ/UFRJ Nicomedes Déscio Pereira Neto Químico Industrial, Mestrando EQ/UFRJ Andressa Gusmão Estagiária, Escola de Química EQ/UFRJ Daniel Hoefle Estagiário, Escola de Química EQ/UFRJ Fernando Tibau Estagiário, Escola de Química EQ/UFRJ Max Arnor Estagiário, Ciências Atuariais IM/UFRJ SUMÁRIO Introdução ............................................................................................................. 5 1. Artigos em biotecnologia .......................................................................... 8 I - Artigos relacionados com a Amazônia ........................................ 10 1. TEMA: BIODIVERSIDADE/BIOPROSPECÇÃO...................................... 11 2. TEMA: DEFESA AGROPECUÁRIA........................................................... 13 3. TEMA: MUDANÇAS CLIMÁTICAS GLOBAIS......................................... 20 4. TEMA: PROGRAMAS DE DESCOBERTA ................................................ 21 II - Artigos relacionados com o Brasil .............................................. 23 1. TEMA: BIODIVERSIDADE/BIOPROSPECÇÃO ....................................... 24 2. TEMA: BIOECONOMIA.............................................................................. 26 3. TEMA: BIORREMEDIAÇÃO....................................................................... 26 4. TEMA: DEFESA AGROPECUÁRIA ............................................................ 27 5. TEMA: INTEGRAÇÃO: ALIMENTAÇÃO, NUTRIÇÃO E SAÚDE ............ 46 6. TEMA: MUDANÇAS CLIMÁTICAS GLOBAIS .......................................... 46 7. TEMA: PROGRAMAS DE DESCOBERTA.................................................. 47 8. TEMA: SEGURANÇA BIOLÓGICA ............................................................ 50 III - Artigos publicados por autores vinculados a instituições brasileiras .................................................................................................... 51 1. TEMA: BIODIVERSIDADE/BIOPROSPECÇÃO ....................................... 52 2. TEMA: BIOECONOMIA.............................................................................. 58 3. TEMA: BIOINDÚSTRIA ............................................................................. 58 4. TEMA: BIOINFORMÁTICA ........................................................................ 59 5. TEMA: BIORREMEDIAÇÃO....................................................................... 60 6. TEMA: CERTIFICAÇÃO DE QUALIDADE BIOLÓGICA .......................... 61 7. TEMA: DEFESA AGROPECUÁRIA ............................................................ 61 8. TEMA: FARMACOGENÉTICA .................................................................... 68 9. TEMA: FERTILIDADE E REPRODUÇÃO ANIMAL ................................... 68 10. TEMA: INTEGRAÇÃO: ALIMENTAÇÃO, NUTRIÇÃO E SAÚDE .......... 69 11. TEMA: MUDANÇAS CLIMÁTICAS GLOBAIS ........................................ 70 12. TEMA: PROGRAMAS DE DESCOBERTA ............................................... 73 13. TEMA: SEGURANÇA BIOLÓGICA.......................................................... 96 14. TEMA: SUSTENTABILIDADE AMBIENTAL ........................................... 98 2. Patentes em biotecnologia ......................................................................100 I. Patentes relacionadas com a Amazônia..................................... 101 1. TEMA: BIOINDÚSTRIA ............................................................................101 2. TEMA: INTEGRAÇÃO: ALIMENTAÇÃO, NUTRIÇÃO E SAÚDE ...........103 3. TEMA: PROGRAMAS DE DESCOBERTA.................................................106 4. TEMA: SUSTENTABILIDADE AMBIENTAL.............................................108 II. Patentes relacionadas com o Brasil................................... 111 1. TEMA: BIOINDÚSTRIA ............................................................................111 2. TEMA: BIORREMEDIAÇÃO......................................................................128 3. TEMA: INTEGRAÇÃO: ALIMENTAÇÃO, NUTRIÇÃO E SAÚDE ...........130 4. TEMA: PROGRAMAS DE DESCOBERTA.................................................139 5. TEMA: SUSTENTABILIDADE AMBIENTAL.............................................147 III. Patentes depositadas no Brasil ........................................... 155 1. TEMA: BIODIVERSIDADE/BIOPROSPECÇÃO ......................................156 2. TEMA: BIOECONOMIA.............................................................................156 3. TEMA: BIOINDÚSTRIA ............................................................................157 4. TEMA: BIORREMEDIAÇÃO......................................................................173 5. TEMA: CERTIFICAÇÃO DE QUALIDADE BIOLÓGICA .........................173 6. TEMA: FERTILIDADE E REPRODUÇÃO ANIMAL ..................................174 7. TEMA: INTEGRAÇÃO: ALIMENTAÇÃO, NUTRIÇÃO E SAÚDE ...........175 8. TEMA: PROGRAMAS DE DESCOBERTA.................................................181 9. TEMA: SEGURANÇA BIOLÓGICA ...........................................................195 10. TEMA: SUSTENTABILIDADE AMBIENTAL ..........................................195 5 Introdução Este relatório tem como objetivo apresentar os títulos de artigos e patentes, do período de 1994-2004, que contém no título ou no resumo os temas e respectivos termos solicitados pelo CGEE e estão relacionados com a Amazônia e Brasil. Desta forma tem-se três sub-conjuntos de artigos e patentes: • Relacionados com a Amazônia • Relacionados com o Brasil • Artigos publicados por autores de instituições brasileiras e patentes depositadas no Brasil. As fontes bibliográficas para este estudo foram a Web of Science para identificação de artigos científicos e Derwent Innovation Index para identificação de patentes. As pesquisas foram realizadas a partir dos temas e termos propostos pelos especialistas em biotecnologia e entregue pelo Prof. Sérgio Salles (UNICAMP representando o CGEE), apresentados na tabela a seguir. Tabela – Temas e termos de busca para monitoramento em biotecnologia BIOTECNOLOGIA TEMAS TERMOS Bancos de germoplasma Herbários e demais formas de conservação ex situ Legislação ágil e eficiente Plantas/Animais e Microbiota Biodiversidade marinha 1.Biodiversidade/ Bioprospecção Acesso ao patrimônio Genético Conhecimento tradicional Mercado de produtos da floresta Propriedade intelectual Fitomedicamentos Mercado Nacional e Internacional Patentes Cadeia produtiva 2. Bioeconomia Inovação tecnológica Projetos pré-competitivos Produtos orgânicos 3. Bioindústria Cadeia produtiva Produtos pré-competitivos Valor agregado Bioprodutos Produtos com alta, média e baixa incorporação de (bio)tecnologia Marketing de Biotecnologia Branding 6 BIOTECNOLOGIA TEMAS TERMOS Designing Redes Software 4. Bioinformática Gestão do conhecimento Aplicações para Genomas, proteomas e biodiversidade Meio ambiente 5. Biorremediação Indústrias com passivo ambiental alto Microorganismos Legislação 6. Bioterrorismo Capacitação de pessoal Inteligência Coleções certificadas 7. Certificação de qualidade biológica Qualidade industrial Microorganismos 8. Competitividade da Economia Nacional Fertilidade e Reprodução Animal Controle de pragas Espécies invasoras Normas internacionais Infra-estrutura para biossegurança Normas de qualidade 9. Defesa Agropecuária Capacidade Antecipativa Leitura de Cenários Capacidade de Integração de Orgãos e Arcabouços Legais Sistemas Efetivos de Monitoramento Recursos Humanos Fármacos Fitomedicamentos 10. Farmacogenética Custo/benefício Genoma de populações Melhoria genômica Competitividade 11. Fertilidade e reprodução animal Clonagem Células tronco Novos fármacos Capital de risco Eficiência das agências públicas 12. Financiamento Formas ágeis de avaliação Capitalização das empresas Espaço para micro-empresas Bancos de dados Propriedade da informação Pessoal qualificado 13. Gestão de Informação Biológica Desenvolvimento de software Integração de Sistemas Redes Cooperativas Nutracêuticos (Alimentos Funcionais) Novas formulações Alimentos especiais para populações especiais Qualidade de vida 14. Integração: alimentação, nutrição e Bem estar saúde Produtos orgânicos Organismos Geneticamente Modificados Produção de Vacinas em Plantas e Animais Produção de Hormônios 7 BIOTECNOLOGIA TEMAS TERMOS Informação 15. Inteligência Quarentenária Espécies invasoras Qualidade agropecuária Ver Biodiversidade/ Bioprospecção 16. Metagenômica/ Prospecção Gênica Remediação ambiental Monitoramento Mudanças nos padrões de produção Processos Evolutivos 17. Mudanças climáticas globais Vetores de Transformação Gênica Expressão Gênica e Ambiente Erradicação de sensibilidade a fotoperíodo Incentivos de P&D voltado para produtos Novas formas de abordagens do material biológico Clonagem Stem Cells Genômica Funcional Farmacogenética 18. Programas de Descoberta Engenharia Genética Nanobiotecnologia Proteômica Evolução direcionada In silico biology Biologia de sistemas Informação Banco de dados Níveis de segurança Laboratórios existentes 19. Segurança Biológica Normas internacionais Pessoal qualificado Qualidade da Segurança Biológica Fluxo Gênico Percepção Pública OGMs Biodisponibilidade de Nutrientes 20. Sustentabilidade
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