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Information provided by Sutter Health’s MyLifeStages and management specialist Pain Comparison Chart Karen Pantazis, M.D.

Painkillers are among the most commonly used in the United States. Deciding which to use deserves careful consideration. Use this quick comparison chart to COMMON SENSE help guide a conversation with your doctor about which CONSIDERATIONS are best and safest for you. • Talk with your doctor about dosage and possible contraindications. • Never take any drugs when you are pregnant without first consulting your doctor. • caution with sensitive groups such as children, the elderly and those with serious health conditions. OVER THE COUNTER

Classification Brand Name Generic Name Best Used For Common Warnings

Bayer Minor aches and , • GI bleeding • May contribute to Bufferin reduction and • Increased bleeding macular degeneration anti-inflammatory • Ulcers • Risk of Reyes syndrome in children Ascriptin and teens Aspirin Ecotrin • Do not combine with blood thinner Family St. Joseph’s medication • Can cause tinnitus in high doses • Can cause kidney problems

Tylenol Acetaminophen Pain and fever • Itching/swelling • Liver damage possible if you take reduction (especially of the face/ more than recommended dose or you tongue/throat) drink alcohol. Acetaminophen • Rash • OTC and flu products contain • Dizziness acetaminophen. It can add up quickly. • Bloody stools Limit total dose per day to 2000 mg. • Stomach bleeding

Advil , Pain, fever reduction and • • May increase risk of Motrin – also known as non anti-inflammatory • Nausea cardiac events and stroke steroidal • Rash • Increases risk of GI bleeding and Aleve NSAIDs • Dizziness perforation • Stomach pain • Can cause kidney problems OVER THE COUNTER [con’t] Classification Brand Name Generic Name Best Used For Common Side Effects Warnings

Midol Preps Combinations of For , • Dizziness • Consider all warnings for aspirin, acet- acetaminophen, bloating, fatigue and • GI bleeding aminophen and NSAIDs like ibuprofen, , naproxen, menstrual symptoms • GI upset since combination drugs may combine Combination aspirin • Irritability one or more classes. Drugs • Nervousness

Vanquish Combination For headaches, • Irritation of stomach or of aspirin, , headaches, intestines Painkillers acetominophen and muscle aches, • Nervousness combining one caffeine menstrual aches, or • Nausea or more classes other minor aches and • Taste problems of OTC drugs. pains due to sinusitis, • Trouble sleeping arthritis, or colds • Ulcer from stomach acid

Excedrin Combinations of pain • Dizziness Migraine acetaminophen, • GI bleeding caffeine and • GI upset ibuprofen • Irritability • Nervousness

PRESCRIPTION

Classification Brand Name Generic Name Best Used For Common Side Effects Warnings

Vicodin and Moderate to • Constipation, nausea, respiratory • Do not overtake these medications! Norco acetaminophen Severe Pain depression in high doses or when Take ONLY as prescribed. mixed with other meds or alcohol, Lortab / Lorcet • Can lead to from respiratory can lead to death depression if overtaken or mixed with other sedatives, including alcohol. Oxycodone Severe Pain • Can lead to dependence and tolerance, Percocet Oxycodone and which are different than addiction. acetaminophen MS ER / Kadian • Can lead to addiction, especially in high risk individuals Methadone Dilaudid Opana Duragesic Patch Patch

Neuropathic Pain Medication Moderate to • Dizziness • Do not stop medication suddenly Severe Pain • Nausea Neurontin Non- Ultram Opioid Lyrica Pregabalin Cymbalta Duloxetine Analgesics Topamax Topiramate Pamelor Nortriptylline

Opioid Agonist / Antagonists Butrans Bupronorphene Patch