Isoquinoline Alkaloids in Diets for Young Growing Pigs Improve Nutrient Digestibility and Gut Health
ISOQUINOLINE ALKALOIDS IN DIETS FOR YOUNG GROWING PIGS IMPROVE NUTRIENT DIGESTIBILITY AND GUT HEALTH BY CARLY MARIE RUNDLE THESIS Submitted in partial fulfillment of the requirements for the degree of Master of Science in Nutritional Sciences in the Graduate College of the University of Illinois at Urbana-Champaign, 2018 Urbana, Illinois Master’s Committee: Associate Professor Ryan N. Dilger, Chair Professor Hans H. Stein, Director Of Research Professor Carl M. Parsons ABSTRACT Three experiments were conducted to evaluate the effects of isoquinoline alkaloids (IQ) in corn-soybean meal (SBM) diets fed to young growing pigs on growth performance, gut health, energy and nutrient digestibility, and digestible energy (DE) and metabolizable energy (ME) concentrations in the diets. In the first experiment, 32 ileal cannulated barrows (12.19 ± 1.38 kg) were allotted to 4 diets with 8 replicate pigs per diet to determine effects of dietary inclusion of IQ on apparent ileal digestibility (AID) of amino acids (AA), crude protein (CP), starch, and acid hydrolyzed ether extract (AEE). The corn-soybean meal basal diet was supplemented with 0, 90, 180, or 360 mg IQ/kg complete feed. Diets were fed for 27 d and ileal digesta were collected on d 13 and 14 (period 1) and d 26 and 27 (period 2). Results indicated that dietary inclusion of IQ resulted in a quadratic increase (P < 0.05) in the AID of starch, Thr, Trp, Val, Pro, and Tyr in period 1. Additionally, the AID of starch was greater (P < 0.05) in period 1 than in period 2. The AID of CP, Arg, His, Ile, Leu, Met, Phe, Thr, Trp, Val, Pro, and Tyr in period 2 was greater (P < 0.05) than in period 1.
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