Integrating Machine Learning and Multiscale Modeling: Perspectives, Challenges, and Opportunities in the Biological, Biomedical, and Behavioral Sciences
Integrating Machine Learning and Multiscale Modeling: Perspectives, Challenges, and Opportunities in the Biological, Biomedical, and Behavioral Sciences Mark Alber, Mathematics, University of California, Riverside Adrian Buganza Tepole, Mechanical Engineering, Purdue University William Cannon, Computational Biology, Pacific Northwest National Lab Suvranu De, Mechanical, Aerospace and Nuclear Engineering, Rensselaer Polytechnic Institute Salvador Dura-Bernal, Physiology & Pharmacology, State University of New York Krishna Garikipati, Mechanical Engineering and Mathematics, University of Michigan George Karniadakis, Division of Applied Mathematics, Brown University William W. Lytton, Physiology & Pharmacology, State University of New York and Kings County Hospital, Brooklyn Paris Perdikaris, Mechanical Engineering, University of Pennsylvania Linda Petzold, Computer Science and Mechanical Engineering, University of California, Santa Barbara Ellen Kuhl, Mechanical Engineering and Bioengineering, Stanford University Abstract. Fueled by breakthrough technology developments, the biological, biomedical, and behavioral sciences are now collecting more data than ever before. There is a critical need for time- and cost-efficient strategies to analyze and interpret these data to advance human health. The recent rise of machine learning as a powerful technique to integrate multimodality, multifidelity data, and reveal correlations between intertwined phenomena presents a special opportunity in this regard. However, machine learning alone ignores the
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