Annual Report
Total Page:16
File Type:pdf, Size:1020Kb
Load more
Recommended publications
-
Perillyl Alcohol Conjugate Downregulates O6-Methylguanin DNA Methltransferase Via Inducing Ubiquitination-De
Song et al. Cell Death and Disease (2018) 9:202 DOI 10.1038/s41419-017-0193-2 Cell Death & Disease ARTICLE Open Access Temozolomide–perillyl alcohol conjugate downregulates O6- methylguanin DNA methltransferase via inducing ubiquitination-dependent proteolysis in non-small cell lung cancer Xingguo Song1,LiXie1,2,MinghuiChang2,3,XinranGeng4,XingwuWang1,ThomasC.Chen5 and Xianrang Song 1,2 Abstract The DNA repair enzyme O6-methylguanin-DNA-methltransferase (MGMT) is able to remove products of alkylating agent such as O6-meG and emerges as a central determinant of cancer resistance to temozolomide (TMZ). Temozolomide–perillyl alcohol conjugate (TMZ–POH), a novel TMZ analog developed based on the conjugation of TMZ and POH, displayed strong anticancer potency in multiple cancer types, but seemed not to experience the chemoresistance even in cells with high MGMT expression unlike TMZ and other alkylating agents. In this study, we demonstrated TMZ–POH inhibited MGMT dependent on proteasomal pathway and this inhibition is a significant factor in its toxic effect in the non-small cell lung cancer (NSCLC) cells. 1234567890():,; 1234567890():,; Introduction such as O6-methyl-guanine (O6-meG), which trigger cell Nowadays, chemotherapy has been traditionally con- cycle-dependent DNA damage and cell death4. Although sidered as one of the standard treatment options for TMZ chemotherapy may enhance survival of cancer cancer patients, but the chemoresistance dramatically patients, intrinsic or acquired resistance to TMZ is also hinders its clinical application, especially for alkylating common and accounts for many treatment failures5, agents like temozolomide (TMZ)1. TMZ, an imidazote- because TMZ-induced DNA alkylation damage can be trazine derivative of the alkylating agent dacarbazine, was repaired by O6-methylguanin-DNA-methltransferase approved by the US FDA (Food and Drug Administration) (MGMT)6. -
Annual Report 2019 X
CHAPTER I Definition 2 CHAPTER XI Corporate Governance Report 102 CHAPTER II Risk Warnings 5 I. Overview of Corporate Governance 102 CHAPTER III Company Profile 6 II. General Meeting 102 I. Profile 6 III. Performance of the Directors 104 II. History 9 IV. Work Performance of Board of Directors and 111 III. Staff Profile 11 Special Committees IV. Brief Introduction of the Organs and Branches 12 V. Chairman and General Manager 123 V. Basic Information about the Industry in Which the 16 VI. Securities Transactions by the Directors, Supervisors and 125 Company Operates Senior Management VI. Business Briefings of the Company 16 VII. Performance of Duties by Independent Non-executive 125 VII. Briefings of our Subsidiaries 17 Directors VIII. Honours Awarded to the Company During the 18 VIII. Supervision on Risk Management and Internal Control 125 Reporting Period System CHAPTER IV Financial Summary 20 IX. Other Relevant Matters 128 I. Major Accounting Data of the Group 20 CHAPTER XII Internal Control 133 II. Major Financial Indexes of the Group 20 I. Establishment of Internal Control Structure 133 III. Net Capital of the Company and Relevant Risk Control 21 II. Implementation and Operation of Internal Control System 133 Indicators III. Supervision and Inspection of Internal Control 133 IV. Financial Conditions of the Group of the Latest Five Years 22 IV. Conclusion of the Assessment of Internal Control 134 CHAPTER V Chairman Statement 23 CHAPTER XIII Independent Auditor’s Report 135 CHAPTER VI Management Discussion and Analysis 25 CHAPTER XIV Notes to the Consolidated Financial 140 I. Economic and Futures Market Analysis during the 25 Statements Reporting Period Consolidated Statements of Comprehensive Income 140 II. -
Distribution of Phthalate Esters in Topsoil: a Case Study in the Yellow River Delta, China
Environ Monit Assess (2013) 185:8489–8500 DOI 10.1007/s10661-013-3190-7 Distribution of phthalate esters in topsoil: a case study in the Yellow River Delta, China Yang Hongjun & Xie Wenjun & Liu Qing & Liu Jingtao & Yu Hongwen & Lu Zhaohua Received: 21 August 2012 /Accepted: 4 April 2013 /Published online: 24 April 2013 # The Author(s) 2013. This article is published with open access at Springerlink.com Abstract TheYellowRiverDelta(YRD)isatypical anthropogenic activities areas (such as the urbanization agricultural and petrochemical industrial area of China. and industrialization), and agriculture influence district, To assess the current status of phthalate esters (PAEs) of which mainly originated from construction waste, mu- soil residues, soil samples (0∼20 cm) (n=82) were col- nicipal sewage, agricultural waste and pesticide, lected in Bincheng District, at the geographic center of discarded plastic effusion and atmospheric depositions. the YRD. PAEs were detected in all topsoil samples Concentrations of PAEs were weakly positivity correlat- analyzed, which indicated that PAEs are ubiquitous en- ed with soil organic carbon content and pH, which vironmental contaminants. Concentrations of 11 PAEs suggested both of them can affect the distribution of are in the range of 0.794∼19.504 μgg−1,withanaverage PAEs. The concentration of di (2-ethylhexyl) phthalate value of 2.975 μgg−1. It was presented that PAEs pollu- and di-n-butyl phthalate dominated in the 11 PAEs, with tion in this area was weak and monotonously increasing the average values of 0.735 and 1.915 μgg−1, respec- along the rural–urban gradient. Higher concentrations tively, and accounted for 92.1 % of the whole PAEs’ were observed from roadsides (and/or gutters), densely concentrations. -
Spatial Optimization and Mode Analysis of Primary Industry Structure in Yellow River Delta Ping Yang, Yujian Yang
Spatial Optimization and Mode Analysis of Primary Industry Structure in Yellow River Delta Ping Yang, Yujian Yang To cite this version: Ping Yang, Yujian Yang. Spatial Optimization and Mode Analysis of Primary Industry Structure in Yellow River Delta. 6th Computer and Computing Technologies in Agriculture (CCTA), Oct 2012, Zhangjiajie, China. pp.150-160, 10.1007/978-3-642-36137-1_19. hal-01348227 HAL Id: hal-01348227 https://hal.inria.fr/hal-01348227 Submitted on 22 Jul 2016 HAL is a multi-disciplinary open access L’archive ouverte pluridisciplinaire HAL, est archive for the deposit and dissemination of sci- destinée au dépôt et à la diffusion de documents entific research documents, whether they are pub- scientifiques de niveau recherche, publiés ou non, lished or not. The documents may come from émanant des établissements d’enseignement et de teaching and research institutions in France or recherche français ou étrangers, des laboratoires abroad, or from public or private research centers. publics ou privés. Distributed under a Creative Commons Attribution| 4.0 International License Spatial Optimization and Mode Analysis of Primary Industry Structure in Yellow River Delta Ping Yang, Yujian Yang* 1 The institute of sustainable development of Shandong Agricultural Science Academy 2S & T Information Engineering Technology Center of Shandong Academy of Agricultural Science, Information center of agronomy College of Shandong University *Corresponding author, Address: S&T Information Engineering Research Center, Number 202 Gongye North Road, -
ATTACHMENT 1 Barcode:3800584-02 C-570-107 INV - Investigation
ATTACHMENT 1 Barcode:3800584-02 C-570-107 INV - Investigation - Chinese Producers of Wooden Cabinets and Vanities Company Name Company Information Company Name: A Shipping A Shipping Street Address: Room 1102, No. 288 Building No 4., Wuhua Road, Hongkou City: Shanghai Company Name: AA Cabinetry AA Cabinetry Street Address: Fanzhong Road Minzhong Town City: Zhongshan Company Name: Achiever Import and Export Co., Ltd. Street Address: No. 103 Taihe Road Gaoming Achiever Import And Export Co., City: Foshan Ltd. Country: PRC Phone: 0757-88828138 Company Name: Adornus Cabinetry Street Address: No.1 Man Xing Road Adornus Cabinetry City: Manshan Town, Lingang District Country: PRC Company Name: Aershin Cabinet Street Address: No.88 Xingyuan Avenue City: Rugao Aershin Cabinet Province/State: Jiangsu Country: PRC Phone: 13801858741 Website: http://www.aershin.com/i14470-m28456.htmIS Company Name: Air Sea Transport Street Address: 10F No. 71, Sung Chiang Road Air Sea Transport City: Taipei Country: Taiwan Company Name: All Ways Forwarding (PRe) Co., Ltd. Street Address: No. 268 South Zhongshan Rd. All Ways Forwarding (China) Co., City: Huangpu Ltd. Zip Code: 200010 Country: PRC Company Name: All Ways Logistics International (Asia Pacific) LLC. Street Address: Room 1106, No. 969 South, Zhongshan Road All Ways Logisitcs Asia City: Shanghai Country: PRC Company Name: Allan Street Address: No.188, Fengtai Road City: Hefei Allan Province/State: Anhui Zip Code: 23041 Country: PRC Company Name: Alliance Asia Co Lim Street Address: 2176 Rm100710 F Ho King Ctr No 2 6 Fa Yuen Street Alliance Asia Co Li City: Mongkok Country: PRC Company Name: ALMI Shipping and Logistics Street Address: Room 601 No. -
Air-Insulated Medium-Voltage Switchgear Nxairs, 24Kv
Air-insulated Medium-Voltage Switchgear NXAirS, 24kV siemens.com.cn/energy-management Air-insulated Medium-Voltage Switchgear NXA irS,24kV Contents Application Types Application Circuit-breaker switchgear NXAirS, is factory-assembled, type-tested, Types metal-enclosed and metal-clad switchgear for indoor installation accoording Typical uses to GB3906, DL404 and IEC 62271-200.. Classification Loss of service continuity category LSC2B (Metal clad) Partition class PM(Metal) Requirements Internal arc classification IAC A FLR ISC≤31.5kA Customer benefits and features arc duration=1s Technical Data Electrical data and dimensions Design data Transportation and packing Primary Solution NXAirS 24kV Design Design of switchgear Components Vacuum circuit-breaker Standards Standards, specifications, guidelines NXAirS panel Maxium rating 24kV/31.5kA/3150A 2 Air-insulated Medium-Voltage Switchgear NXA irS,24kV Air-insulated Medium-Voltage Switchgear NXAirS,24kV Contents Application Application Types Application Typical uses Classification Application Circuit-breaker switchgear NXAirS, is factory-assembled, type-tested, NXAirS circuit-breaker switchgear is used in NXAirS switchgear correspond to the following classifications according to GB3906, Types metal-enclosed and metal-clad switchgear for indoor installation accoording Typical uses substations and distribution system, mainly at the DL404 and IEC62271-200. to GB3906, DL404 and IEC 62271-200.. Classification primary distribution level. E.g. Loss of service continuity category Loss of service continuity -
Table of Codes for Each Court of Each Level
Table of Codes for Each Court of Each Level Corresponding Type Chinese Court Region Court Name Administrative Name Code Code Area Supreme People’s Court 最高人民法院 最高法 Higher People's Court of 北京市高级人民 Beijing 京 110000 1 Beijing Municipality 法院 Municipality No. 1 Intermediate People's 北京市第一中级 京 01 2 Court of Beijing Municipality 人民法院 Shijingshan Shijingshan District People’s 北京市石景山区 京 0107 110107 District of Beijing 1 Court of Beijing Municipality 人民法院 Municipality Haidian District of Haidian District People’s 北京市海淀区人 京 0108 110108 Beijing 1 Court of Beijing Municipality 民法院 Municipality Mentougou Mentougou District People’s 北京市门头沟区 京 0109 110109 District of Beijing 1 Court of Beijing Municipality 人民法院 Municipality Changping Changping District People’s 北京市昌平区人 京 0114 110114 District of Beijing 1 Court of Beijing Municipality 民法院 Municipality Yanqing County People’s 延庆县人民法院 京 0229 110229 Yanqing County 1 Court No. 2 Intermediate People's 北京市第二中级 京 02 2 Court of Beijing Municipality 人民法院 Dongcheng Dongcheng District People’s 北京市东城区人 京 0101 110101 District of Beijing 1 Court of Beijing Municipality 民法院 Municipality Xicheng District Xicheng District People’s 北京市西城区人 京 0102 110102 of Beijing 1 Court of Beijing Municipality 民法院 Municipality Fengtai District of Fengtai District People’s 北京市丰台区人 京 0106 110106 Beijing 1 Court of Beijing Municipality 民法院 Municipality 1 Fangshan District Fangshan District People’s 北京市房山区人 京 0111 110111 of Beijing 1 Court of Beijing Municipality 民法院 Municipality Daxing District of Daxing District People’s 北京市大兴区人 京 0115 -
Study on Spatial Model and Service Radius of Rural Areas And
Study on Spatial Model and Service Radius of Rural Areas and Agriculture Information Level in Yellow-river Delta Yujian Yang1, Guangming Liu2, Xueqin Tong1, Zhicheng Wang1 1.S & T Information Engineering Technology Center of Shandong Academy of Agricultural Science, Information center of agronomy College of Shandong University Jinan 250100, P. R. China 2. Institute of Soil Science, Chinese Academy of Sciences, Nanjing 210008, P. R. China 1 Corresponding author, Address: S&T Information Engineering Research Center, Number 202 Gongye North Road, Licheng District of Jinan, 250100, Shandong Province, P. R. China, Tel: +86-531-83179076, Fax:+86-531-83179821, Email:[email protected] Abstract. Based on the evaluation methods and systems of information measurement level, and according to the principles of agriculture information subject, the study constructed 13 indices system for the measurement of the rural areas and agriculture information level in Yellow-river Delta in 2007. Spatial autocorrelation model of rural areas and agriculture information of 19 country units showed that the comprehensive information level of Hanting, Shouguang, Guangrao, Bincheng, Huimin, Wudi and Yangxin country unit is very significant, has the obvious spatial agglomeration and homogeneity characteristics, but information level agglomeration of Kenli country and Zouping city has the significant heterogeneity, and information level agglomeration characteristics of other 10 country units is not significant. The radius surface of the complicated information level from radial basis function model indicated that rural areas and agriculture information service has a certain service radius, the distance of service radius in theory is 30Km, the gradient and hierarchy is obvious. According to it, the comprehensive service node should be established in Bincheng district and the secondary service node should be set up in Wudi country for improving the service efficiency. -
Shandong Dezhou Investment Delegation to ASEAN
Shandong Dezhou Investment Delegation to ASEAN CONTENTS Social and Economic Survey of Dezhou………………………………………………………………………….2 Competitive Industry of Dezhou....…………………………………………………………………………………4 CCPIT Dezhou Branch & CCIOC Dezhou Chamber…………………………………………………………..9 Shandong Dexing Group Construction Engineering Co., Ltd…………………………………………..11 Shandong Huahai Group Co., Ltd…………………………………………………………………………………13 Shandong Xin jiekou Culturaland Creative Industrial Zone …………………………………………..15 Shandong K.D.L. Textile Co., Ltd…..………………………………………………………………………………17 Dezhou Liyuan International Co.,Ltd……………………………………………………………………………19 Dezhou Huaqiang Trade Co. Ltd.………………………………………………………………………………….21 Shandong Dexing Group Gear Logistics Co., Ltd……………………………………………………………23 Hebei Dongfang Iron Tower Co., Ltd…………………….………………………………………………………25 LiuShun Automation Equipment Co., Ltd.………………………………………………………………….....27 Dezhou Huizhong Automobile Sales Co. Ltd. ………………………………………………………………..29 Leling Derum Health Food Co., Ltd…………………………………………………………………………........31 Shandong Yichang Lighting Technology Co, Ltd……………………………………………………….......33 Shandong Jitai Welding Materials Co., Ltd……………………………………………………………………35 Shandong Derun New Material Technology Co., Ltd…………………………………….……………….37 Shandong Fuyang Biotechnology Co., Ltd ……………………………………………………………………39 Ji'nan Hua Kaiyuan Co., Ltd………………………………………………………………………………………...41 Shandong HuaQiang New Material Co., Ltd………………………………………………………………….43 China Huayang Economic and Trade Group Co., Ltd. (HuayangGroup)……………………………………………………………………………………………………….45 1 Social -
List of Main Production Facilities of ALDI Nord's Suppliers for Apparel
List of Main Production Facilities of ALDI Nord‘s Suppliers for Apparel, Home Textiles and Shoes Version: April 2021 Produktionsstättenliste | März 2018 | Seite 0/17 Name Address Number of Employees Commodity Group Bangladesh AB Apparels Ltd. 225, Singair Road, Tetuljhora, Hemayetpur 2001 - 5000 Garment textiles Ador Composite Ltd. 1, C & B Bazar, Gilarchala, Sreepur 1001 - 2000 Garment textiles AKH Eco Apparels Ltd. 495, Balitha, Shahbelishwar, Dhamrai 5001 - 10000 Garment textiles Angshuk Ltd. 133-134, Hamayetpur, Savar 501 - 1000 Garment textiles Apparels Village Ltd. Khagan, Birulia, Savar 2001 - 5000 Garment textiles Aspire Garments Ltd. 491, Dhalla, Singair 2001 - 5000 Garment textiles B.H.I.S. Apparels Ltd. 671, Datta Para, Hossain Market, Tongi 2001 - 5000 Garment textiles Blue Planet Knitwear Ltd. Mulaid, P.O.: Tengra, Sreepur 1001 - 2000 Garment textiles Chaity Composite Ltd. Chotto Silmondi, Tripurdi, Sonargaon 5001 - 10000 Garment textiles Chantik Garments Ltd. Kumkumari, Gouripur, Ashulia, Savar 2001 - 5000 Garment textiles Chorka Textile Ltd. Kajirchor, Danga Bazar, Polash 2001 - 5000 Garment textiles Citadel Apparels Ltd. Joy Bangla Road, Kunia, K.B. Bazar, Gazipur Sadar 501 - 1000 Garment textiles Cotton Dyeing & Finishing Mills Ltd. Vill: Amtoli, Union: 10 No. Habirbari, P.O-Seedstore Bazar, P.S.-Valuka 1001 - 2000 Garment textiles Crossline Factory (Pvt) Ltd. 25, Vadam, Uttarpara, Nishatnagar, Tongi 1001 - 2000 Garment textiles Plot No. 45, 48, 49, 51 & 52; Holding No.: 3/C, Vadam, P.O.: Crossline Knit Fabrics Ltd. 1001 - 2000 Garment textiles Nishatnagar, Tongi, Gazipur-1711, Gazipur Crown Exclusive Wears Ltd. Mawna, Sreepur 2001 - 5000 Garment textiles Crown Fashion & Sweater Industries Ltd. Plot No. 781-782, Vogra, Joydebpur, Gazipur-1704 2001 - 5000 Garment textiles Denim Fashions Ltd. -
Peach John Co., Ltd. Partner Factory List 「株式会社ピーチ・ジョン」の製造委託先工場リスト
As of 30 June 2019/ 2019年6月30日時点 Peach John Co., Ltd. Partner Factory List 「株式会社ピーチ・ジョン」の製造委託先工場リスト No. Country Factory Name Factory Address 4F, 51 Qingxia Road, Yuhuangling Industrial Park, Chengyang 1 China B.BLOSSOM FASHION CO.,LTD. District, Qingdao, China BINYANG XINBAOFENG GARMENT Third Floor, Standard Workshop 4, Shigu Ling Industrial Park B 2 China CO.,LTD. uilding, Litang Industrial Park, Guangxi Binyang County, China BINZHOUSHI RUIYI GARMENT 3 China Bincheng District Bingzhou, Shandong, China CO.,LTD. CHAOZHOU XIANGQIAO HENG HONG Fl 1/4, Workshop Of Lan Hua San St, Garden Development Zone, 4 China DA ART & CRAFT CLOTHES Chaozhou, China MANUFACTORY 5 China DALIAN AILIDA GARMENT CO.,LTD. Beihai Industrial Zone, Maoyingzi, Ganjingzi District, Dalian, China 6 China DALIAN IVY FASHION CO.,LTD. No.646 Hongcheng Road, Ganjingzi District, Dalian, China 7 China DALIAN MODA FASHION CO.,LTD. Xisosi Village, Xinhua Street, Zhuangue City, Dalian, China 8 China DALIAN SHUYA FASHION CO.,LTD. Tangli Industrial Park, Hongqizhen Ganjingzi District, Dalian, China No.65 Xinyi, Street Xinzhaizi Town, Ganjingzi District, Dalian, 9 China DALIAN TIANAI FASHION CO.,LTD. China No.552 Dongshanhou Cun, Sanshilipu Town, Jinzhou New District, 10 China DALIAN YOU LAN GARMENTS CO.,LTD. Dalian, China Lingwu Industrial Complex, Gaobu Town, Dongguan City, 11 China DONGGUAN TANI APPAREL CO.,LTD. Guangdong, China Xian Yuan Pu Industrial Area, Da Li Village Qing Xi Town, 12 China IDEAL GARMENTS CO.,LTD. Dongguan City, Guangdong, China Xiaoguo Road, Economic Development Zone, Lingbi, Suzhou, 13 China LING BI XIAN YILU GARMENT CO.,LTD. Anhui, China NANTONG DONG FANG STAR 14 China No.388 Guo Qiang Road, Gan Zha Q Nantong, China GARMENT FACTORY LIMITED NANTONG SAITA INTERNATIONAL Xuean Industrial Park, Dongchen Town, Rugao, Nantong, 15 China TRADE CO.,LTD. -
2012 Annual Report 2017-10-17
www.cs.ecitic.com (a joint stock limited company incorporated in the People’s Republic of China with limited liability) (STOCK CODE : 6030) 2012 ANNUAL REPORT This annual report is printed on environmental paper. IMPORTANT NOTICE The Board and the supervisory committee of the Company and the Directors, Supervisors and Senior Management warrant the truthfulness, accuracy and completeness of the report and that there is no false representation, misleading statement contained herein or material omission from this report, and for which they will assume joint and several liabilities. This report was considered and approved at the 11th Meeting of the 5th Session of the Board of the Company. All Directors of the Company attended the meeting. No Director or Supervisor submitted any objection to this report. The Company’s 2012 profi t distribution proposal considered by the Board is a cash dividend of RMB3.00 for every 10 shares (tax inclusive), and is subject to the approval of the general meeting of the Company. The domestic and international annual fi nancial reports of the Company were audited by Ernst & Young Hua Ming LLP and Ernst & Young respectively, and auditor’s reports with standard unqualifi ed audit opinions were issued accordingly. Mr. WANG Dongming, Chairman of the Company, and Mr. GE Xiaobo, the person-in-charge of accounting affairs and the head of the Company’s fi nancial department, warrant that the fi nancial statements set out in this annual report are true, accurate and complete. There was no appropriation of funds of the Company by connected parties for non-operating purposes.