DOCSLIB.ORG

Furosemide 20Mg Tablets

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Furosemide 20Mg Tablets Furosemide 20mg tablets Read all of this leaflet carefully before you start Check with your doctor or pharmacist before taking taking this medicine. Furosemide tablets if you have: • Keep this leaflet. You may need to read it again. • low blood volume (hypovolaemia) or are at risk of developing low • If you have any further questions, ask your blood pressure doctor or pharmacist. • low levels of protein in the blood (hypoproteinaemia) as a result of kidney damage • This medicine has been prescribed for you. Do • liver congestion (slowed blood flow through the vessels) or other not pass it on to others. It may harm them, even liver problems if their symptoms are the same as yours. • kidney problems • If any of the side effects get serious, or if you • or may have diabetes. If you are taking insulin, your doctor may notice any side effects not listed in this leaflet, need to adjust your insulin dosage please tell your doctor or pharmacist. • are elderly, if you are on other medications which can cause the drop of blood pressure and if you have other medical conditions that are risks for the drop of blood pressure Index • prostate trouble or difficulty passing urine 1 What Furosemide tablets are and what • or have had gout • have an abnormal blood condition they are used for • are about to undergo any blood or urine tests 2 Before you take Your doctor will want to monitor you, and may take blood for 3 How to take testing while you are taking this medicine. Taking other medicines 4 Possible side effects Please tell your doctor or pharmacist if you are taking or have 5 How to store recently taken any other medicines, including medicines obtained without a prescription. Especially: 6 Further information • drugs to lower blood pressure, such as ACE inhibitors, renin inhibitors, alpha blockers, calcium channel blockers, diuretics, phenothiazines 1 What Furosemide tablets are and what they are • drugs to treat mental illness (e.g. pimozide, amisulpride, used for sertindole) Furosemide tablets is one of a group of medicines called diuretics • drugs for arrhythmias (e.g. sotalol, amiodarone, flecanide) (water tablets). • digoxin for your heart Your doctor has prescribed Furosemide tablets to treat a condition • moxisylte for Raynaud’s syndrome called oedema where there is too much water in your body. This • nitrates (for angina) could be due to problems with your heart, kidneys, liver, blood • lithium for depression or mania vessels or high blood pressure. Furosemide helps your kidneys to get • sucralfate for stomach ulcers rid of the extra water that is not needed in your body. • colestyramine or colestipol for high cholesterol • non-steroidal anti-inflammatory drugs (NSAIDs) e.g. ibuprofen or 2 Before you take naproxen Do not take Furosemide tablets if you: • aspirin for pain • are allergic (hypersensitive) to furosemide, other sulfonamide • antibiotics for infections that affect your kidneys or ears (e.g. related drugs or any of the other ingredients in Furosemide tablets cefaclor, colistin, gentamicin, vancomycin) (see section 6) • amphoterecin (to treat fungal infections) • have severe kidney damage which has stopped them working • chloral hydrate (to treat insomnia) properly and producing urine • antidepressants (e.g. monoamine oxidase inhibitors (MAOIs)) • have very low levels of potassium, sodium or other electrolytes • medicines to control diabetes such as insulin or tablets in your blood or low blood volume (your doctor will be able to • antiepileptics e.g. phenytoin or carbamazepine advise you) • corticosteroids or antihistamines (to treat allergic reactions) • are dehydrated • drugs for ADHD • have low blood pressure • drugs treating cancer e.g. aldesleukin • take potassium supplements or potassium sparing diuretics for • levodopa (for Parkinson’s disease) high blood pressure (e.g. amiloride or spironolactone) • oral contraceptives • have liver cirrhosis (tiredness, weakness, water retention, feeling or • alprostadil for erectile dysfunction being sick, loss of weight or appetite, yellowing skin or eyes, itch ) or • certain treatments for asthma such as theophylline or salbutamol liver encephalopathy (confusion, altered levels of consciousness • probenecid to prevent gout and coma as a result of liver failure) • laxatives used over a long period of time • have Addison’s disease (low levels of corticosteroid hormones • medicines or foods containing liquorice secreted) • if you are about to undergo a procedure where curariform muscle • have digitalis poisoning (feeling or being sick, high levels of relaxants (e.g. vercuronium) or anaesthetics may be used, tell your potassium in the blood, slow, fast or irregular heart beats). anaesthetist/dentist or healthcare professional • are breast-feeding Furosemide and alcohol You should avoid drinking alcohol while taking Furosemide tablets as this may lower your blood pressure further. Continued top of next column Continued over page 148x210 Leaflet Reel Fed Profile (BST) Furosemide Tablets 20mg x 28’s (UK) Furosemide 20mg 28 Tablets PIL - UK JDE No.: 50970662 approved for print/date Dimensions: 148x210 (Reel Fed) Item number: BBBA5260 Colours Non Printing Colours 1. Black 1. Profile Originator: T. Hull Dimensions: 148x210 Component: Leaflet for Blisters Origination Date: 20.06.2019 Min Body Text Size: 7pt 2. 2. Revision Date: 06.12.2019 Supplier: Accord Barnstaple 3. 3. Pharmacode: 6913 Revised By: T. Hull 4. 5. Proof Round Date Sent: 13/06/19 Technical Date sent: n/a 6. 4 Approval Date received: n/a Technologist: T. Hull [email protected] Technically Approved FMD info NA (not a carton) £ No £ Yes £ Details * Please note that only Artwork Studio is permitted to make changes to the above artwork. Version 2 No changes are permitted by any 3rd party other than added notes and mark ups for required changes. 01.11.2017 Pregnancy and breast-feeding • Light-headedness, sensations of pressure in the head, headache, Speak to your doctor before you take Furosemide tablets if you are drowsiness, weakness, changes in vision, dry mouth, dizziness when pregnant, thinking of getting pregnant, or breast-feeding. standing. • Irregular heartbeat Driving and using machines • Muscle cramps or weakness Do not drive or operate machinery if you feel less alert after taking • Changes in the amount or need to urinate Furosemide tablets. • Tiredness Important information about some of the ingredients in Furosemide • Dry mouth, thirst, feeling or being sick, changes in bowel movements tablets including diarrhoea and constipation Your medicine contains lactose; do not take Furosemide tablets if you • Deafness (sometimes irreversible) have been told by your doctor that you have an intolerance to a sugar Rare: may affect up to 1 in 1,000 people called lactose. • Changes in blood cells such as amount of white blood cells, reduction 3 How to take of platelets causing a rash fever, sweating, tiredness, and weight loss. Your doctor will perform regular blood tests to ensure no changes have Always take Furosemide tablets exactly as your doctor has told you. occurred. If you are not sure, check with your doctor or pharmacist. • Psychiatric disorder NOC causing delusions, hallucinations, disorganized Swallow the tablets with a glass of water. speech • Feeling ‘pins and needles’ or tingling sensation Doses: • Confusion, headache, tiredness, generally feeling unwell, fever • Adults and children over 12 years: • ‘Ringing’ in the ears, loss of hearing usually reversible Water retention: the usual starting dose is 40mg in the morning, then • Symptoms of shock such as changes in heart rate, breathlessness, cool 20mg a day or 40mg on alternate days. Up to 80mg a day may be given. clammy skin High blood pressure: 20-40mg twice a day. • Inflammation of the pancreas causing pains in your abdomen or back • Elderly: may be reduced in this age group. and nausea • Children under 12 years: 1-3mg per kg of bodyweight. A more suitable • Changes in the liver causing yellowing of the skin or whites of the eyes) dosage form e.g. oral solution, may be appropriate. • Skin rashes Dosage adjustment may be necessary in patients with: • hypoproteinaemia Very rare: may affect up to 1 in 10,000 people • liver congestion/dysfunction • Involuntary movements of the muscle • Inflammation or failure of the kidney which may cause back pain or If you take more than you should changes in the amount or need to urinate If you take more medicine than your doctor has told you to, contact a doctor or your nearest hospital casualty department immediately and Not known: frequency cannot be estimated from the available data take your Furosemide tablets with you. Symptoms of an overdose include • Worsening of conditions where there is already balances of fluid or dehydration, changes in the levels of certain chemicals in the blood and chemicals in the body low blood pressure. • Acute generalised exanthematous pustulosis (AGEP) (acute febrile drug eruption) If you forget to take the tablets • Dizziness, fainting and loss of consciousness (caused by symptomatic If you forget to take a dose, take another as soon as you remember. Then hypotension) take your next dose at the normal time. Do not take double the amount to • Decreased levels of potassium in the body make up for a forgotten dose. Additional side effects in children If you stop taking Furosemide tablets • Increased risk or persistence of patent ductus arteriosus in premature Speak to your doctor before you stop taking Furosemide tablets. infants. • Kidney stones in infants
Load more

Recommended publications
  • 268 Part 522—Implantation Or Injectable Dosage Form
    § 520.2645 21 CFR Ch. I (4–1–18 Edition) (ii) Indications for use. For the control 522.82 Aminopropazine. of American foulbrood (Paenibacillus 522.84 Beta-aminopropionitrile. larvae). 522.88 Amoxicillin. 522.90 Ampicillin injectable dosage forms. (iii) Limitations. The drug should be 522.90a Ampicillin trihydrate suspension. fed early in the spring or fall and con- 522.90b Ampicillin trihydrate powder for in- sumed by the bees before the main jection. honey flow begins, to avoid contamina- 522.90c Ampicillin sodium. tion of production honey. Complete 522.144 Arsenamide. treatments at least 4 weeks before 522.147 Atipamezole. main honey flow. 522.150 Azaperone. 522.161 Betamethasone. [40 FR 13838, Mar. 27, 1975, as amended at 50 522.163 Betamethasone dipropionate and FR 49841, Dec. 5, 1985; 59 FR 14365, Mar. 28, betamethasone sodium phosphate aque- 1994; 62 FR 39443, July 23, 1997; 68 FR 24879, ous suspension. May 9, 2003; 70 FR 69439, Nov. 16, 2005; 73 FR 522.167 Betamethasone sodium phosphate 76946, Dec. 18, 2008; 75 FR 76259, Dec. 8, 2010; and betamethasone acetate. 76 FR 59024, Sept. 23, 2011; 77 FR 29217, May 522.204 Boldenone. 17, 2012; 79 FR 37620, July 2, 2014; 79 FR 53136, 522.224 Bupivacaine. Sept. 8, 2014; 79 FR 64116, Oct. 28, 2014; 80 FR 522.230 Buprenorphine. 34278, June 16, 2015; 81 FR 48702, July 26, 2016] 522.234 Butamisole. 522.246 Butorphanol. § 520.2645 Tylvalosin. 522.275 N-Butylscopolammonium. 522.300 Carfentanil. (a) Specifications. Granules containing 522.304 Carprofen. 62.5 percent tylvalosin (w/w) as 522.311 Cefovecin.
    [Show full text]
  • Sample Chapter
    LCMS_Chap09 (JB-D) 8/5/06 3:14 pm Page 193 9 LC-MS in doping control Detlef Thieme Introduction adjacent fields with similar analytical prospects, like veterinary residue control (predominantly dealing with identification of growth promoters Definition of doping in various matrices), forensic sciences (the major- ity of doping-relevant substances are scheduled Doping analysis comprises a diversity of sub- as controlled substances in most countries), stance classes with different pharmaceutical and environmental analysis (e.g. steroids in waste chemical properties. Therefore, the discussion of water) or clinical chemistry (e.g. due to the the suitability of liquid chromatography-mass increasing relevance of steroid hormone replace- spectrometry (LC-MS) in doping analysis needs ment therapy). to distinguish various categories. This chapter describes the key fields of appli- According to its formal definition, a doping cation of LC-MS in routine doping control (i.e. violation in sports can be caused by various screening analysis, confirmation and quantifica- events, e.g.: tion of positive results) extra to particular • the detection of a prohibited substance or research activities. The latter are focused on the metabolites or markers of that substance (as intended technical improvements (e.g. extension defined by the recent document [1] of the of detection time windows, reduction of turn- World Anti-Doping Agency [WADA]) in the around times and costs) of conventional analyti- athlete’s specimen cal procedures and, in particular, on the detection • the use of prohibited substances or methods of prohibited substances that cannot be ade- • possession or trafficking prohibited substances quately identified so far (e.g.
    [Show full text]
  • DIURETICS Diuretics Are Drugs That Promote the Output of Urine Excreted by the Kidneys
    DIURETICS Diuretics are drugs that promote the output of urine excreted by the Kidneys. The primary action of most diuretics is the direct inhibition of Na+ transport at one or more of the four major anatomical sites along the nephron, where Na+ reabsorption takes place. The increased excretion of water and electrolytes by the kidneys is dependent on three different processes viz., glomerular filtration, tubular reabsorption (active and passive) and tubular secretion. Diuretics are very effective in the treatment of Cardiac oedema, specifically the one related with congestive heart failure. They are employed extensively in various types of disorders, for example, nephritic syndrome, diabetes insipidus, nutritional oedema, cirrhosis of the liver, hypertension, oedema of pregnancy and also to lower intraocular and cerebrospinal fluid pressure. Therapeutic Uses of Diuretics i) Congestive Heart Failure: The choice of the diuretic would depend on the severity of the disorder. In an emergency like acute pulmonary oedema, intravenous Furosemide or Sodium ethacrynate may be given. In less severe cases. Hydrochlorothiazide or Chlorthalidone may be used. Potassium-sparing diuretics like Spironolactone or Triamterene may be added to thiazide therapy. ii) Essential hypertension: The thiazides usually sever as primary antihypertensive agents. They may be used as sole agents in patients with mild hypertension or combined with other antihypertensives in more severe cases. iii) Hepatic cirrhosis: Potassium-sparing diuretics like Spironolactone may be employed. If Spironolactone alone fails, then a thiazide diuretic can be added cautiously. Furosemide or Ethacrymnic acid may have to be used if the oedema is regractory, together with spironolactone to lessen potassium loss. Serum potassium levels should be monitored periodically.
    [Show full text]
  • Uniform Classification Guidelines for Foreign Substances and Recommended Penalties Model Rule
    DRUG TESTING STANDARDS AND PRACTICES PROGRAM. Uniform Classification Guidelines for Foreign Substances And Recommended Penalties Model Rule. January, 2018 (V.13.4) Ó ASSOCIATION OF RACING COMMISSIONERS INTERNATIONAL – 2018. Association of Racing Commissioners International 1510 Newtown Pike, Lexington, Kentucky, United States www.arci.com Page 1 of 61 Preamble to the Uniform Classification Guidelines of Foreign Substances The Preamble to the Uniform Classification Guidelines was approved by the RCI Drug Testing and Quality Assurance Program Committee (now the Drug Testing Standards and Practices Program Committee) on August 26, 1991. Minor revisions to the Preamble were made by the Drug Classification subcommittee (now the Veterinary Pharmacologists Subcommittee) on September 3, 1991. "The Uniform Classification Guidelines printed on the following pages are intended to assist stewards, hearing officers and racing commissioners in evaluating the seriousness of alleged violations of medication and prohibited substance rules in racing jurisdictions. Practicing equine veterinarians, state veterinarians, and equine pharmacologists are available and should be consulted to explain the pharmacological effects of the drugs listed in each class prior to any decisions with respect to penalities to be imposed. The ranking of drugs is based on their pharmacology, their ability to influence the outcome of a race, whether or not they have legitimate therapeutic uses in the racing horse, or other evidence that they may be used improperly. These classes of drugs are intended only as guidelines and should be employed only to assist persons adjudicating facts and opinions in understanding the seriousness of the alleged offenses. The facts of each case are always different and there may be mitigating circumstances which should always be considered.
    [Show full text]
  • Mechanisms of Sevoflurane-Induced Myocardial Preconditioning In
    Anesthesiology 2003; 99:27–33 © 2003 American Society of Anesthesiologists, Inc. Lippincott Williams & Wilkins, Inc. Mechanisms of Sevoflurane-induced Myocardial Preconditioning in Isolated Human Right Atria In Vitro Alexandra Yvon, B.Sc.,* Jean-Luc Hanouz, M.D, Ph.D.,† Benoît Haelewyn, B.Sc.,* Xavier Terrien, B.Sc.,* Massimo Massetti, M.D.,‡ Gérard Babatasi, M.D., Ph.D.,‡ André Khayat, M.D.,§ Pierre Ducouret, Ph.D.,࿣ Henri Bricard, M.D.,# Jean-Louis Gérard, M.D., Ph.D.** Background: The authors examined the role of adenosine postischemic contractile function,5–7 and metabolic triphosphate–sensitive potassium channels and adenosine A 7 1 function. Although the mechanisms involved in anes- receptors in sevoflurane-induced preconditioning on isolated thetic preconditioning remain incompletely understood, human myocardium. Methods: The authors recorded isometric contraction of hu- protein kinase C, adenosine triphosphate–sensitive po- man right atrial trabeculae suspended in oxygenated Tyrode’s tassium (KATP) channels, and adenosine A1 receptors Downloaded from http://pubs.asahq.org/anesthesiology/article-pdf/99/1/27/408853/0000542-200307000-00008.pdf by guest on 02 October 2021 solution (34°C; stimulation frequency, 1 Hz). In all groups, a seem to play a key role.1,2,5,6 However, recent studies 30-min hypoxic period was followed by 60 min of reoxygenation. suggest that volatile anesthetic–induced myocardial pre- Seven minutes before hypoxia reoxygenation, muscles were ex- posed to 4 min of hypoxia and 7 min of reoxygenation or 15 min conditioning may be dependent on species and experi- 5,8 of sevoflurane at concentrations of 1, 2, and 3%. In separate mental models.
    [Show full text]
  • FAST FACTS and CONCEPTS #20 OPIOID DOSE ESCALATION in END-OF-LIFE CARE David E Weissman MD, Andrew Kamell MD Background a Comm
    FAST FACTS AND CONCEPTS #20 OPIOID DOSE ESCALATION IN END-OF-LIFE CARE David E Weissman MD, Andrew Kamell MD Background A common question from trainees is “How fast, and by how much, can opioids be safely dose escalated in terminally ill patients?” Consider the analogy of furosemide (Lasix) when discussing this topic. An increase in Lasix from 10 mg to 11 mg is unheard of, yet that is precisely what often happens with opioids, especially parenteral infusions. For example, increasing a morphine infusion from 1 to 2 mg/hr is a 100% does increase; while going from 5 to 6 mg/hr is only a 20% increase. Yet, many orders are written, “increase drip by 1 mg/hr, titrate to comfort.” Some hospitals and nursing units even have this as a standing order or nursing policy. Such titration orders are unlikely to lead to be effective. Key clinical considerations for appropriate opioid escalation: 1. Is an opioid dose escalation appropriate? To answer that question, clinicians need to consider: a. Is the patient tolerating opioids well with little adverse effects? b. Is the pain or dyspnea expected to continue at a similar or progressive pattern (particularly relevant for scheduled medications or infusions) or might it be temporary? c. Is the source of discomfort opioid responsive? d. Is there evidence of hyperalgesia or neurotoxicity from opioids? See Fast Facts #57,58, and 142. e. Is the pain related to a chronic, non-malignant source in which the patient has an extended prognosis? If so, then aggressive opioid titrations may not be the best long-term solution.
    [Show full text]
  • Drug and Medication Classification Schedule
    KENTUCKY HORSE RACING COMMISSION UNIFORM DRUG, MEDICATION, AND SUBSTANCE CLASSIFICATION SCHEDULE KHRC 8-020-1 (11/2018) Class A drugs, medications, and substances are those (1) that have the highest potential to influence performance in the equine athlete, regardless of their approval by the United States Food and Drug Administration, or (2) that lack approval by the United States Food and Drug Administration but have pharmacologic effects similar to certain Class B drugs, medications, or substances that are approved by the United States Food and Drug Administration. Acecarbromal Bolasterone Cimaterol Divalproex Fluanisone Acetophenazine Boldione Citalopram Dixyrazine Fludiazepam Adinazolam Brimondine Cllibucaine Donepezil Flunitrazepam Alcuronium Bromazepam Clobazam Dopamine Fluopromazine Alfentanil Bromfenac Clocapramine Doxacurium Fluoresone Almotriptan Bromisovalum Clomethiazole Doxapram Fluoxetine Alphaprodine Bromocriptine Clomipramine Doxazosin Flupenthixol Alpidem Bromperidol Clonazepam Doxefazepam Flupirtine Alprazolam Brotizolam Clorazepate Doxepin Flurazepam Alprenolol Bufexamac Clormecaine Droperidol Fluspirilene Althesin Bupivacaine Clostebol Duloxetine Flutoprazepam Aminorex Buprenorphine Clothiapine Eletriptan Fluvoxamine Amisulpride Buspirone Clotiazepam Enalapril Formebolone Amitriptyline Bupropion Cloxazolam Enciprazine Fosinopril Amobarbital Butabartital Clozapine Endorphins Furzabol Amoxapine Butacaine Cobratoxin Enkephalins Galantamine Amperozide Butalbital Cocaine Ephedrine Gallamine Amphetamine Butanilicaine Codeine
    [Show full text]
  • 2021 Formulary List of Covered Prescription Drugs
    2021 Formulary List of covered prescription drugs This drug list applies to all Individual HMO products and the following Small Group HMO products: Sharp Platinum 90 Performance HMO, Sharp Platinum 90 Performance HMO AI-AN, Sharp Platinum 90 Premier HMO, Sharp Platinum 90 Premier HMO AI-AN, Sharp Gold 80 Performance HMO, Sharp Gold 80 Performance HMO AI-AN, Sharp Gold 80 Premier HMO, Sharp Gold 80 Premier HMO AI-AN, Sharp Silver 70 Performance HMO, Sharp Silver 70 Performance HMO AI-AN, Sharp Silver 70 Premier HMO, Sharp Silver 70 Premier HMO AI-AN, Sharp Silver 73 Performance HMO, Sharp Silver 73 Premier HMO, Sharp Silver 87 Performance HMO, Sharp Silver 87 Premier HMO, Sharp Silver 94 Performance HMO, Sharp Silver 94 Premier HMO, Sharp Bronze 60 Performance HMO, Sharp Bronze 60 Performance HMO AI-AN, Sharp Bronze 60 Premier HDHP HMO, Sharp Bronze 60 Premier HDHP HMO AI-AN, Sharp Minimum Coverage Performance HMO, Sharp $0 Cost Share Performance HMO AI-AN, Sharp $0 Cost Share Premier HMO AI-AN, Sharp Silver 70 Off Exchange Performance HMO, Sharp Silver 70 Off Exchange Premier HMO, Sharp Performance Platinum 90 HMO 0/15 + Child Dental, Sharp Premier Platinum 90 HMO 0/20 + Child Dental, Sharp Performance Gold 80 HMO 350 /25 + Child Dental, Sharp Premier Gold 80 HMO 250/35 + Child Dental, Sharp Performance Silver 70 HMO 2250/50 + Child Dental, Sharp Premier Silver 70 HMO 2250/55 + Child Dental, Sharp Premier Silver 70 HDHP HMO 2500/20% + Child Dental, Sharp Performance Bronze 60 HMO 6300/65 + Child Dental, Sharp Premier Bronze 60 HDHP HMO
    [Show full text]
  • 218 Part 522—Implantation Or Injectable Dosage Form
    Pt. 522 21 CFR Ch. I (4–1–07 Edition) by Mycoplasma gallisepticum sensitive 522.82 Aminopropazine fumarate sterile so- to tylosin. lution injection. (iii) Limitations. Do not use in layers 522.84 Beta-aminopropionitrile fumarate. 522.88 Sterile amoxicillin trihydrate for sus- producing eggs for human consump- pension. tion; administer from 2 to 5 days as 522.90 Ampicillin implantation and sole source of drinking water; treated injectible dosage forms. turkeys should consume enough medi- 522.90a Ampicillin trihydrate sterile suspen- cated drinking water to provide 60 mil- sion. ligrams of tylosin per pound of body 522.90b Ampicillin trihydrate for sterile sus- weight per day; prepare a fresh solu- pension. tion every 3 days; when sinus swelling 522.90c Ampicillin sodium for aqueous injec- tion. is present, inject the sinus with tylosin 522.144 Arsenamide sodium aqueous injec- injectable simultaneously with the tion. drinking water treatment; do not ad- 522.147 Atipamezole. minister within 5 days of slaughter. 522.150 Azaperone injection. (3) Swine—(i) Amount. 0.25 gram per 522.161 Betamethasone acetate and gallon. betamethasone disodium phosphate aque- (ii) Indications for use. For the control ous suspension. 522.163 Betamethasone dipropionate and and treatment of swine dysentery betamethasone sodium phosphate aque- (bloody scours) caused by pathogens ous suspension. sensitive to tylosin. 522.204 Boldenone. (iii) Limitations. As only source of 522.234 Butamisole hydrochloride. drinking water for 3 to 10 days, depend- 522.246 Butorphanol tartrate injection. ing on the severity of the condition 522.275 N-Butylscopolammonium bromide. being treated: mix fresh solution daily; 522.311 Carfentanil citrate injection.
    [Show full text]
  • These Highlights Do Not Include All the Information Needed to Use PRASTERA® Safely and Effectively
    PRASTERA- prasterone and ibuprofen Health Science Funding, LLC Disclaimer: This drug has not been found by FDA to be safe and effective, and this labeling has not been approved by FDA. For further information about unapproved drugs, click here. ---------- HIGHLIGHTS OF PRESCRIBING INFORMATION These highlights do not include all the information needed to use PRASTERA® safely and effectively. See full prescribing information for PRASTERA® . PRASTERA® prasterone oral softgels 200mg are for oral use only. Initial U.S. Approval INDICATIONS AND USAGE PRASTERA® prasterone 200 mg oral softgels is indicated in female patients with mild to moderate, active (SLEDAI ≥2) systemic lupus erythematosus (SLE) to restore serum 5-dehydroandrosterone sulfate to levels typical of women without SLE. In Phase III clinical trials in female patients with mild to moderate active SLE, prasterone 200 mg was associated with reduced risk of auto-immune flare, reduced risk of breast cancer and reduced risk of death from any cause. (§§1, 6.2, 6.4, 6.5) DOSAGE AND ADMINISTRATION The recommended dose is one (1) softgel daily. (§2) DOSAGE FORMS AND STRENGTHS 200mg oral softgel capsules supplied in a convenience package with ibuprofen oral tablets 400mg. (§3) CONTRAINDICATIONS Known hypersensitivity to any of its ingredients. (§4) Undiagnosed abnormal genital bleeding. (§4) Known, suspected or history of breast cancer. (§4, §6.5) History of, or known, deep vein thrombosis, pulmonary embolism, arterial thromboembolic disease (e.g., stroke, myocardial infarction). (§4) Hypercholesterolemia or ischemic heart disease. (§4, §7.2.4) Hepatic or renal impairment (pharmacokinetic data lacking). (§4, §7.2) Breast-feeding or known or suspected pregnancy.
    [Show full text]
  • Early Refill Drug Utilization Review Drugs
    Early Refill Drug Utilization Review Drugs Published: 05/01/2012 Point-of-Sale Drug Authorization and Policy Drug Name Effective Date Override Override Center Override Acarbose X 11/8/2008 Acebutolol hydrochloride X 11/8/2008 acetaminophen X 11/8/2008 acetazolamide X 11/8/2008 acetazolamide sodium X 11/8/2008 acetylcholine X 11/8/2008 acetylcysteine X 11/8/2008 Acitretin X 11/8/2008 Acrivastine X 11/8/2008 activated charcoal X 11/8/2008 adalimumab X 11/8/2008 Adapalene X 11/8/2008 Adenosine X 11/8/2008 albumin human X 11/8/2008 Albuterol X 11/8/2008 albuterol sulfate X 11/8/2008 alclometasone dipropionate X 11/8/2008 aldesleukin X 11/8/2008 alendronate sodium X 11/8/2008 alfentanil hydrochloride X 11/8/2008 aliskiren hemifumarate X 11/8/2008 Alitretinoin X 11/8/2008 almotriptan malate X 11/8/2008 alosetron hydrochloride X 11/8/2008 Alprazolam X 1/6/2010 Aluminum X 11/8/2008 aluminum sulfate X 11/8/2008 amantadine hydrochloride X 11/8/2008 amcinonide X 11/8/2008 amino acids X 11/8/2008 aminophylline X 11/8/2008 amiodarone hydrochloride X 11/8/2008 amitriptyline hydrochloride X 11/8/2008 amlodipine besylate X 11/8/2008 Ammonium X 11/8/2008 Ammonium chloride X 11/8/2008 amobarbital X 1/6/2010 Point-of-Sale Drug Authorization and Policy Drug Name Effective Date Override Override Center Override Amoxicillin trihydrate X 11/8/2008 amphetamine X 1/6/2010 amyl nitrite X 11/8/2008 Amylase X 11/8/2008 apraclonidine hydrochloride X 11/8/2008 arformoterol tartrate X 11/8/2008 Arginine X 11/8/2008 arginine hydrochloride X 11/8/2008 aripiprazole X
    [Show full text]
  • Presented By: Dr. Joohee Pradhan Assistant Professor Department of Pharmaceutical Sciences, MLSU, Udaipur
    Presented By: Dr. Joohee Pradhan Assistant Professor Department of Pharmaceutical Sciences, MLSU, Udaipur OUTLINE • Introduction and Definition • Relevant Physiology of Urine Formation • Classification: different ways • Carbonic anhydrase inhibitors: Acetazolamide*, Methazolamide, Dichlorphenamide. • Thiazides: Chlorthiazide*, Hydrochlorothiazide, Hydroflumethiazide, Cyclothiazide, • Loop diuretics: Furosemide*, Bumetanide, Ethacrynic acid. • Potassium sparing Diuretics: Spironolactone, Triamterene, Amiloride. • Osmotic Diuretics: Mannitol 2 Introduction and Definition • Diuretics (natriuretics) are drugs which cause a net loss of Na+ and water in urine and hence increase the urine output (or) urine volume. • The primary action of most diuretics is the direct inhibition of Na+ reabsorption (increased excretion) at one or more of the four major sites along the nephron. • An increased Na+ excretion is accompanied by anion like Cl- Since NaCl is the major determinant of extracellular fluid volume; Diuretics reduce extracellular fluid volume (decrease in oedema) by decreasing total body NaCl content. 3 Introduction and Definition • Diuretics are very effective in the treatment of conditions like: o chronic heart failure o nephrotic syndrome o chronic hepatic diseases o hypertension o Pregnancy associated oedema o Cirrhosis of the liver. 4 Relevant Physiology of Urine Formation • Kidneys are the organs responsible for urine formation. Two important functions of the kidney are: o To maintain a homeostatis balance of electrolytes and water. o To excrete water soluble end products of metabolites. • Each kidney contains approximately one million nephrons and is capable of forming urine independently. • Urine formation starts from glomerular filtration (g.f.) in a prodigal way. • Normally, about 180 L of fluid is filtered everyday: all soluble constituents of blood minus the plasma proteins (along with substances bound to them) and lipids, are filtered at the glomerulus.
    [Show full text]