Information for Vermont Prescribers of Prescription Drugs

ALUNBRIG® (Brigatinib) Capsules

This list does not imply that the products on this chart are interchangeable or have the same efficacy or safety. Please refer to each product's FDA-approved label and indication for further information.

The prices listed below are Average Wholesale Prices ("AWP") as established and made available to the public by a third partypublisher or as calculated from data made available to the public by a third party publisher. The price paid by consumers may be higher or lower than the prices listedbelow. Information about AWP of these drugs is being provided to Vermont prescribers pursuant to Vermont law, to give you information about the relative prices of marketed drugs and other drugs in the same therapeutic class.

The prices listed here do not necessarily reflect price per dosage, price per course of treatment or the cost effectiveness, of all the products listed. For simplicity, only the smallest package sizes available for each product are included.

Price Comparison: Marketed product and lowest dosage of other products in same therapeutic class*

Marketed Product AWP Per Pill Alunbrig Oral Tablet 30 MG $227.00

Droxia Oral Capsule 200 MG $0.91 Hydroxyurea Oral Capsule 500 MG $1.10 Hydrea Oral Capsule 500 MG $1.64 Flutamide Oral Capsule 125 MG $1.91 Cyclophosphamide Oral Tablet 25 MG $3.54 Methotrexate Sodium Oral Tablet 2.5 MG $3.56 Mercaptopurine Oral Tablet 50 MG $6.15 Methotrexate Oral Tablet 2.5 MG $6.24 Siklos Oral Tablet 100 MG $6.30 Cyclophosphamide Oral Capsule 25 MG $8.50 Capecitabine Oral Tablet 150 MG $10.30 Lysodren Oral Tablet 500 MG $12.16 Melphalan Oral Tablet 2 MG $12.21 Venclexta Oral Tablet 10 MG $12.91 Alkeran Oral Tablet 2 MG $13.58 Temozolomide Oral Capsule 5 MG $13.84 Bicalutamide Oral Tablet 50 MG $15.91 Xeloda Oral Tablet 150 MG $16.27 Abiraterone Acetate Oral Tablet 250 MG $16.50 Trexall Oral Tablet 5 MG $19.32 Emcyt Oral Capsule 140 MG $19.34 Myleran Oral Tablet 2 MG $28.11 Tretinoin Oral Capsule 10 MG $30.32 Tabloid Oral Tablet 40 MG $30.33 Leukeran Oral Tablet 2 MG $31.82 Zelboraf Oral Tablet 240 MG $54.25 Lapatinib Ditosylate Oral Tablet 250 MG $60.14 Tykerb Oral Tablet 250 MG $66.83 Alecensa Oral Capsule 150 MG $79.29 Mektovi Oral Tablet 15 MG $82.92 Tazverik Oral Tablet 200 MG $82.93 Lumakras Oral Tablet 120 MG $89.50 Tafinlar Oral Capsule 50 MG $90.06 Koselugo Oral Capsule 10 MG $90.73 Yonsa Oral Tablet 125 MG $94.85 Erlotinib HCl Oral Tablet 25 MG $95.55 Tukysa Oral Tablet 50 MG $98.44 Etoposide Oral Capsule 50 MG $100.44 Tarceva Oral Tablet 25 MG $108.82 Zytiga Oral Tablet 250 MG $108.87 Gleostine Oral Capsule 10 MG $109.16 Inlyta Oral Tablet 1 MG $110.86 Gleevec Oral Tablet 100 MG $112.37 Nerlynx Oral Tablet 40 MG $116.75 Nubeqa Oral Tablet 300 MG $118.97 Hycamtin Oral Capsule 0.25 MG $120.59 Xtandi Oral Capsule 40 MG $122.76 Xtandi Oral Tablet 40 MG $122.76 Matulane Oral Capsule 50 MG $124.90 Braftovi Oral Capsule 75 MG $126.77 Erleada Oral Tablet 60 MG $128.33 Casodex Oral Tablet 50 MG $131.85 Cotellic Oral Tablet 20 MG $133.43 Brukinsa Oral Capsule 80 MG $134.91 Retevmo Oral Capsule 40 MG $137.33 Lynparza Oral Tablet 100 MG $144.49 Votrient Oral Tablet 200 MG $145.57 Mekinist Oral Tablet 0.5 MG $148.09

Source: Medi-Span Price Rx, 07/06/2021 Page 1 of 2 Marketed Product AWP Per Pill Zolinza Oral Capsule 100 MG $150.10 Zykadia Oral Tablet 150 MG $152.20 Ukoniq Oral Tablet 200 MG $159.00 Bosulif Oral Tablet 100 MG $164.57 Sprycel Oral Tablet 20 MG $168.24 Tasigna Oral Capsule 50 MG $168.71 Rubraca Oral Tablet 200 MG $173.70 Imatinib Mesylate Oral Tablet 100 MG $178.87 Gavreto Oral Capsule 100 MG $192.43 Rydapt Oral Capsule 25 MG $202.75 Tabrecta Oral Tablet 150 MG $202.90 Turalio Oral Capsule 200 MG $202.95 Talzenna Oral Capsule 0.25 MG $205.14 NexAVAR Oral Tablet 200 MG $207.60 Lonsurf Oral Tablet 15-6.14 MG $215.07 Vitrakvi Oral Capsule 25 MG $218.67 Inrebic Oral Capsule 100 MG $219.45 Nilutamide Oral Tablet 150 MG $225.24 Alunbrig Oral Tablet 30 MG $227.00 Rozlytrek Oral Capsule 100 MG $230.72 Zydelig Oral Tablet 100 MG $235.41 Lorbrena Oral Tablet 25 MG $236.02 Bexarotene Oral Capsule 75 MG $237.93 Sutent Oral Capsule 12.5 MG $242.51 Cometriq (60 MG Daily Dose) Oral Kit 20 MG $257.13 Stivarga Oral Tablet 40 MG $267.82 Verzenio Oral Tablet 50 MG $279.82 Calquence Oral Capsule 100 MG $281.28 Jakafi Oral Tablet 5 MG $295.08 Targretin Oral Capsule 75 MG $298.50 Zejula Oral Capsule 100 MG $304.87 Caprelsa Oral Tablet 100 MG $308.58 Iressa Oral Tablet 250 MG $311.56 Copiktra Oral Capsule 15 MG $320.67 Kisqali (200 MG Dose) Oral Tablet Therapy Pack 200 MG $323.89 Xospata Oral Tablet 40 MG $324.45 Nilandron Oral Tablet 150 MG $328.16 Balversa Oral Tablet 3 MG $354.83 Xalkori Oral Capsule 200 MG $371.73 Daurismo Oral Tablet 25 MG $373.20 Gilotrif Oral Tablet 20 MG $403.30 Tepmetko Oral Tablet 225 MG $417.97 Qinlock Oral Tablet 50 MG $447.60 Odomzo Oral Capsule 200 MG $498.48 Erivedge Oral Capsule 150 MG $504.25 Temodar Oral Capsule 100 MG $546.72 Vizimpro Oral Tablet 15 MG $546.84 Tibsovo Oral Tablet 250 MG $567.60 Everolimus Oral Tablet 2.5 MG $589.70 Imbruvica Oral Capsule 70 MG $596.81 Tagrisso Oral Tablet 40 MG $608.34 Truseltiq (50MG Daily Dose) Oral Capsule Therapy Pack 25 MG $614.29 Afinitor Disperz Oral Tablet Soluble 2 MG $640.34 Iclusig Oral Tablet 10 MG $716.52 Ibrance Oral Tablet 75 MG $746.96 Piqray (200 MG Daily Dose) Oral Tablet Therapy Pack 200 MG $749.88 Lenvima (4 MG Daily Dose) Oral Capsule Therapy Pack 4 MG $787.48 Cabometyx Oral Tablet 20 MG $866.51 Revlimid Oral Capsule 2.5 MG $956.81 Pomalyst Oral Capsule 1 MG $1,089.13 IDHIFA Oral Tablet 50 MG $1,129.84 Ayvakit Oral Tablet 25 MG $1,342.72 Fotivda Oral Capsule 0.89 MG $1,380.00 Pemazyre Oral Tablet 4.5 MG $1,457.14 Inqovi Oral Tablet 35-100 MG $1,798.80 Onureg Oral Tablet 200 MG $1,813.55 Farydak Oral Capsule 10 MG $2,816.50 Ninlaro Oral Capsule 2.3 MG $4,358.60 Xpovio (40 MG Once Weekly) Oral Tablet Therapy Pack 40 MG $6,923.40

*Prices shown are for the lowest dosage of each product. Prices for multi-source products have been averaged. Multiple forms of the same product (e.g. tabs and caps) have been considered one product, and the prices have been averaged. Chewable forms of the product are not included.

For additional price comparison information, see: http://takeda.info/Alunbrig-VT-LF

Source: Medi-Span Price Rx, 07/06/2021 Page 2 of 2