Progress Report Annual Report on Reactor Safety Research Projects
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Cannabinoids and Endocannabinoid System Changes in Intestinal Inflammation and Colorectal Cancer
cancers Review Cannabinoids and Endocannabinoid System Changes in Intestinal Inflammation and Colorectal Cancer Viktoriia Cherkasova, Olga Kovalchuk * and Igor Kovalchuk * Department of Biological Sciences, University of Lethbridge, Lethbridge, AB T1K 7X8, Canada; [email protected] * Correspondence: [email protected] (O.K.); [email protected] (I.K.) Simple Summary: In recent years, multiple preclinical studies have shown that changes in endo- cannabinoid system signaling may have various effects on intestinal inflammation and colorectal cancer. However, not all tumors can respond to cannabinoid therapy in the same manner. Given that colorectal cancer is a heterogeneous disease with different genomic landscapes, experiments with cannabinoids should involve different molecular subtypes, emerging mutations, and various stages of the disease. We hope that this review can help researchers form a comprehensive understanding of cannabinoid interactions in colorectal cancer and intestinal bowel diseases. We believe that selecting a particular experimental model based on the disease’s genetic landscape is a crucial step in the drug discovery, which eventually may tremendously benefit patient’s treatment outcomes and bring us one step closer to individualized medicine. Abstract: Despite the multiple preventive measures and treatment options, colorectal cancer holds a significant place in the world’s disease and mortality rates. The development of novel therapy is in Citation: Cherkasova, V.; Kovalchuk, critical need, and based on recent experimental data, cannabinoids could become excellent candidates. O.; Kovalchuk, I. Cannabinoids and This review covered known experimental studies regarding the effects of cannabinoids on intestinal Endocannabinoid System Changes in inflammation and colorectal cancer. In our opinion, because colorectal cancer is a heterogeneous Intestinal Inflammation and disease with different genomic landscapes, the choice of cannabinoids for tumor prevention and Colorectal Cancer. -
CZECH MYCOLOGY Formerly Česká Mykologie Published Quarterly by the Czech Scientific Society for Mycology
r 7|— I VOLUME 48 L ^ Z - t U M M A Y 1 9 9 5 My c o l o g y l CZECH SCIENTIFIC SOCIETY FOR MYCOLOGY PRAHA JSAYCU N l . o Clov J < M ^/\YCU ISSN 0009-0476 n§ ! r % . O o v J < Vol. 48, No. 1, May 1995 CZECH MYCOLOGY formerly Česká mykologie published quarterly by the Czech Scientific Society for Mycology EDITORIAL BOARD Editor-in-Chief ZDENĚK POUZAR (Praha) Managing editor ; JAROSLAV KLÁN (Praha) VLADIMÍR ANTONÍN (Brno) JIŘÍ KUNERT (Olomouc) OLGA FASSATIOVÁ (Praha) LUDMILA MARVANOVÁ (Brno) ROSTISLAV FELLNER (Praha) PETR PIKÁLEK (Praha) JOSEF HERINK (Mnichovo Hradiště) MIRKO SVRČEK (Praha) Czech Mycology is an international scientific journal publishing papers in all aspects of mycology. Publication in the journal is open to members of the Czech Scientific Society for Mycology and non-members. Contributions to: Czech Mycology, National Museum, Department of Mycology, Václavské nám. 68, 115 79 Praha 1, Czech Republic. Phone: 02/24230485 SUBSCRIPTION. Annual subscription is Kč 250,- (including postage). The annual sub scription for abroad is US $80,- (including postage). The annual membership fee of the Czech Scientific Society for Mycology (Kč 160,- or US $ 60,- for foreigners) includes the journal without any other additional payment. For subscriptions, address changes, pay ment and further information please contact The Czech Scientific Society for Mycology, P.O.Box 106, 11121 Praha 1, Czech Republic. Copyright © The Czech Scientific Society for Mycology, Prague, 1995 : No. 4 of the vol. 47 of Czech Mycology appeared in February 16, 1995 CZECH MYCOLOGY Publication of the Czech Scientific Society for Mycology Volume 48 May 1995 Number 1 Articles published in this number of Czech Mycology were presented at 7th International Congress of Mycology Division (IUMS - 94) in Prague, July 3 - 8, 1994. -
Iii. Administración Local
BOCM BOLETÍN OFICIAL DE LA COMUNIDAD DE MADRID Pág. 468 LUNES 21 DE MARZO DE 2011 B.O.C.M. Núm. 67 III. ADMINISTRACIÓN LOCAL AYUNTAMIENTO DE 17 MADRID RÉGIMEN ECONÓMICO Agencia Tributaria Madrid Subdirección General de Recaudación En los expedientes que se tramitan en esta Subdirección General de Recaudación con- forme al procedimiento de apremio, se ha intentado la notificación cuya clave se indica en la columna “TN”, sin que haya podido practicarse por causas no imputables a esta Administra- ción. Al amparo de lo dispuesto en el artículo 112 de la Ley 58/2003, de 17 de diciembre, Ge- neral Tributaria (“Boletín Oficial del Estado” número 302, de 18 de diciembre), por el presen- te anuncio se emplaza a los interesados que se consignan en el anexo adjunto, a fin de que comparezcan ante el Órgano y Oficina Municipal que se especifica en el mismo, con el obje- to de serles entregada la respectiva notificación. A tal efecto, se les señala que deberán comparecer en cualquiera de las Oficinas de Atención Integral al Contribuyente, dentro del plazo de los quince días naturales al de la pu- blicación del presente anuncio en el BOLETÍN OFICIAL DE LA COMUNIDAD DE MADRID, de lunes a jueves, entre las nueve y las diecisiete horas, y los viernes y el mes de agosto, entre las nueve y las catorce horas. Quedan advertidos de que, transcurrido dicho plazo sin que tuviere lugar su compare- cencia, se entenderá producida la notificación a todos los efectos legales desde el día si- guiente al del vencimiento del plazo señalado. -
Smiths Abound Discussion Document
Smiths Abound According to Wikipedia, Smith is the most common surname in the United Kingdom, Australia and the United States, and second only to Li in Canada. It is the fifth most common surname in Ireland. Worldwide there are about 5 million Smiths; data on how many live in the U.S.is conflicting, but at least 2.4 million. Therefore, it’s not surprising that people who bear the surname Smith have chosen to have their own holiday on January 6. The event seems to have been started by Adrienne Sioux Koopersmith in 1995, in part to find help in tracing her own genealogy. She chose January 6th because it was the birthday in 1580 of Captain John Smith, the English colonial leader who helped to settle Jamestown, Virginia in 1607, thereby bringing the name to North American shores. The word “smith” derives from the word “smite” or “strike,” and although there has been a suggestion that Smiths originally derived their name from the occupation of soldiers (smiting the enemy), most present day Smiths are probably descendants of blacksmiths who worked with black metals, such as iron. Related names include: • Whitesmith and Tinsmith for those who worked with tin • Coppersmith (or in Adrienne’s case) Koopersmith for those who worked with copper, and Brownsmith, Redsmith, and Greensmith for the color of copper when it oxidized • Silversmith and Goldsmith, obviously for those who worked with silver and gold In addition, of course, there are people named Smythe, Smithers, Smitherman, Smithson, or Smithwick, all related in one way or another to their laboring ancestors. -
And Oxidative Stress in the Differentiation of SH-SY5Y Cells
Hernandez-Martinez, Juan-Manuel (2015) Role of kynurenines and oxidative stress in the differentiation of SH-SY5Y cells. PhD thesis. http://theses.gla.ac.uk/6133/ Copyright and moral rights for this thesis are retained by the author A copy can be downloaded for personal non-commercial research or study, without prior permission or charge This thesis cannot be reproduced or quoted extensively from without first obtaining permission in writing from the Author The content must not be changed in any way or sold commercially in any format or medium without the formal permission of the Author When referring to this work, full bibliographic details including the author, title, awarding institution and date of the thesis must be given Glasgow Theses Service http://theses.gla.ac.uk/ [email protected] Role of Kynurenines and Oxidative Stress in the Differentiation of SH-SY5Y Cells Juan-Manuel Hernandez-Martinez B.Sc. (UNAM) A thesis submitted in fulfilment of the requirements for the Degree of PhD Institute of Neuroscience and Psychology College of Medical, Veterinary and Life Sciences University of Glasgow September 2014 Abstract Neuroblastoma is the most common solid extracranial tumour in children. The neuroblastoma SH-SY5Y cell line is a third successive subclone established from a metastatic bone tumour biopsy. It can be induced to differentiate (regress) into a neuronal phenotype when treated with any of several molecules including retinoic acid (RA). This characteristic has been exploited in several studies that use the SH-SY5Y cell line as a neuronal model. These studies have had far- reaching implications in shaping our understanding of certain key aspects of neurotoxicity and neurodevelopment yet their genuine relevance becomes evident when approached from an oncological point of view, as they provide information about the process underlying tumour regression which in turn can lead to the development of better therapies for the clinical management of this malignancy. -
Magazin Wirtschaft
www.stuttgart.ihk.de 07.2013 Stuttgart - Böblingen - Esslingen-Nürtingen - Göppingen - Ludwigsburg - Rems-Murr Magazin Wirtschaft Ein Service der IHK für Unternehmen in der Region Stuttgart Fachkräfte finden zwischen Alb und Gäu Seite 6 wer hat schon ein ganzes kabinett nur für diewirtschaft? Selbstverständlich wir. Damit die Betriebe gute Rahmenbedingungen haben, sind in unseren Gremien ausschließlich Wirtschaftexperten vertreten. www.stuttgart.ihk.de oder Infoline 0711 2005-0 EDITORIAL Handelskriege kennen keine Gewinner Ähnlich dem Frühjahrswetter in diesem weit kommen? China ist die zweitgrößte Wirt- Jahr ziehen nun auch Wolken über dem schaftsmacht der Welt. Daher sollte das Land Parkett des internationalen Handels beginnen, sich an internationale Spielregeln auf. Auslöser ist die vorläufige Erhebung von zu halten. Globalisierung benötigt faire Wett- EU-Strafzöllen auf chinesische Solarmodule. bewerbsbedingungen, an die sich China zu- China kontert mit einem Anti-Dumping-Ver- weilen jedoch nicht hält. Belegte Fälle von fahren gegen europäischen Wein. Immer Wettbewerbsverstößen gibt es genug. mehr Produkte treten in den Fokus der Dum- ping-Diskussion. Vernünftige Handelspolitik Die EU muss schnellstens sieht anders aus. Mangels Deeskalation wird Verhandlungen aufnehmen die Situation für China und Europa immer tassilo zywietz unangenehmer. Ein Handelskrieg droht. Europa darf davor die Augen nicht ver- Geschäftsführer International Globalisierung erfordert jedoch gegensei- schließen. Nachgiebigkeit ist keine Erfolg ver- der IHK Region Stuttgart tige Rücksichtnahme und Handeln im Sinne sprechende Strategie – damit würde die EU der immer stärker miteinander verbundenen erpressbar. Lässt man China gewähren, kann Volkswirtschaften: China und die EU haben die Methode künftig in der Chemiebranche letztes Jahr Waren und Dienstleistungen in und irgendwann im Autobau angewendet Höhe von über 400 Milliarden Euro ausge- werden. -
Zion Lutheran's Surname List
Zion Lutheran Church Records 1861–1961, Belleville, Illinois—surnames of families found in this book. © 2011 St. Clair County Genealogical Society, P.O. Box 431, Belleville, IL 62222-0431. Early records of this church—translated from German—include 4200 baptisms with parents named, 2700 confirmation entries, 1268 marriages, 1360 burials, witnesses and sponsors. A CDRom publication is planned by the SCCGS. Interested in a copy? Contact the Society via one of the website www.stclair-ilgs.org links posted there. _EIMAND ANDRECK BAEHR BARTHELHEIMER BEIRAND BETTERTSCH ABEL ANDREGG BAETTGER BARTLING BEISER BETZ ABENDROTH ANDRES BAEUERLE BARTON BEISSWINGERT BEUDA ABERLE ANDREW BAEUMER BARTS BEITERMANN BEURMANN ABRAHAMSON ANDREWS BAGNAUER BARTTELBORT BEITHAUS BEUSE ACHISON ANDRO BAGNET BARTZ BELCOUR BEUTENBACH ACHS ANDRUSHAT BAGSHAW BATER BELINSKI BEUTNAGEL ACKER ANNA BAHORCE BATMAN BELKER BEVIART ACKERMANN ANSTETTE BAHORICH BATRIE BELKERS BEWART ACOEN ANTEROPP BAHR BATSSTE BELL BEYER ADAMS ANTHES BAIER BATTELBORD BELLEVILLE BEYERLEY ADAMSON ANTHONY BAIL BATTOE BELLOFF BICKEL ADELMANN ANTON BAILEY BAUCHER BELMKE BIEBEL ADEN APEL BAKER BAUER BENDE BIEBER ADKINS APPERSON BALAICH BAUMAN BENDER BIEBN ADLER AREY BALARCH BAUMANN BENDIN BIEDERMANN ADRIAN ARING BALARICK BAUMGARTEN BENDINGER BIEHL AGLES ARL BALDEN BAUMGARTNER BENEDICK BIEHLHORN AGNE ARMANNO BALDWIN BAUMUNCH BENEDICT BIEN AHLEMEYER ARMANNS BALKE BAYER BENING BIERERLY AHLERS ARMBRUST BALL BAZ BENNIKE BIERLENBACH AHLERSMEIER ARMBRUSTER BALLHAUS BEAN BENNING BIERMANN AHLERSMEYER ARMENO BALSEKER -
Marriage Certificates
GROOM LAST NAME GROOM FIRST NAME BRIDE LAST NAME BRIDE FIRST NAME DATE PLACE Abbott Calvin Smerdon Dalkey Irene Mae Davies 8/22/1926 Batavia Abbott George William Winslow Genevieve M. 4/6/1920Alabama Abbotte Consalato Debale Angeline 10/01/192 Batavia Abell John P. Gilfillaus(?) Eleanor Rose 6/4/1928South Byron Abrahamson Henry Paul Fullerton Juanita Blanche 10/1/1931 Batavia Abrams Albert Skye Berusha 4/17/1916Akron, Erie Co. Acheson Harry Queal Margaret Laura 7/21/1933Batavia Acheson Herbert Robert Mcarthy Lydia Elizabeth 8/22/1934 Batavia Acker Clarence Merton Lathrop Fannie Irene 3/23/1929East Bethany Acker George Joseph Fulbrook Dorothy Elizabeth 5/4/1935 Batavia Ackerman Charles Marshall Brumsted Isabel Sara 9/7/1917 Batavia Ackerson Elmer Schwartz Elizabeth M. 2/26/1908Le Roy Ackerson Glen D. Mills Marjorie E. 02/06/1913 Oakfield Ackerson Raymond George Sherman Eleanora E. Amelia 10/25/1927 Batavia Ackert Daniel H. Fisher Catherine M. 08/08/1916 Oakfield Ackley Irving Amos Reid Elizabeth Helen 03/17/1926 Le Roy Acquisto Paul V. Happ Elsie L. 8/27/1925Niagara Falls, Niagara Co. Acton Robert Edward Derr Faith Emma 6/14/1913Brockport, Monroe Co. Adamowicz Ian Kizewicz Joseta 5/14/1917Batavia Adams Charles F. Morton Blanche C. 4/30/1908Le Roy Adams Edward Vice Jane 4/20/1908Batavia Adams Edward Albert Considine Mary 4/6/1920Batavia Adams Elmer Burrows Elsie M. 6/6/1911East Pembroke Adams Frank Leslie Miller Myrtle M. 02/22/1922 Brockport, Monroe Co. Adams George Lester Rebman Florence Evelyn 10/21/1926 Corfu Adams John Benjamin Ford Ada Edith 5/19/1920Batavia Adams Joseph Lawrence Fulton Mary Isabel 5/21/1927Batavia Adams Lawrence Leonard Boyd Amy Lillian 03/02/1918 Le Roy Adams Newton B. -
Surname Index to Schenectady Births 1940-1953
Grems-Doolittle Library Schenectady County Historical Society 32 Washington Ave. Schenectady, NY 12305 Surname Index to Schenectady Births 1940-1953 Abare Abele Ackley Abba Abele Ackroyd Abbale Abeles Ackroyd Abbale Abeles Ackroyd Abbale Abell (probably Abeel) Ackroyd Abbatiello Abelone (probably Acord Abbatiello Abelove) Acree Abbatiello Abelove Acree (probably Abbatiello Aberbach or Aberback Aeree) Abbato Aberback Acton Abbato Abercrombie Acton Abbato Aboudara Acucena Abbe Abraham Adack Abbott Abrahamson (not - Adack or Adach Abbott nson) Adair Abbott Abrams Adair Abbott Abrams Adair Abbott Abramson Adair Abbott Abrofsky Adair Abbott Abt Adair Abbott Aceto Adam Abbott Aceto Adamczak Abbott Aceto Adamec Abbott Aceto Adamec Abbott Acken Adamec Abbott Acker Adamec Abbott Acker Adamek Abbott Acker Adamek Abbzle = ? spelling Acker Adamkiewicz unclear Acker Adamkiewicz Abeel Ackerle Adams Abeel Ackerman Adams Abeel Ackerman Adams Abeel Ackerman Adams Abeel Ackerman Adams Abel Ackley Adams Grems-Doolittle Library Schenectady County Historical Society 32 Washington Ave. Schenectady, NY 12305 Surname Index to Schenectady Births 1940-1953 Adams Adamson Ahl Adams Adanti Ahles Adams Addis Ahman Adams Ademec or Adamec Ahnert Adams Adinolfi Ahren Adams Adinolfi Ahren Adams Adinolfi Ahrendtsen Adams Adinolfi Ahrendtsen Adams Adkins Ahrens Adams Adkins Ahrens Adams Adriance Ahrens Adams Adsit Aiken Adams Aeree Aiken Adams Aernecke Ailes = ? Adams Agans Ainsworth Adams Agans Aker (or Aeher = ?) Adams Aganz (Agans ?) Akers Adams Agare or Abare = ? Akerson Adams Agat Akin Adams Agat Akins Adams Agen Akins Adams Aggen Akland Adams Aggen Albanese Adams Aggen Alberding Adams Aggen Albert Adams Agnew Albert Adams Agnew Albert or Alberti Adams Agnew Alberti Adams Agostara Alberti Adams Agostara (not Agostra) Alberts Adamski Agree Albig Adamski Ahave ? = totally Albig Adamson unclear Albohm Adamson Ahern Albohm Adamson Ahl Albohm (not Albolm) Adamson Ahl Albrezzi Grems-Doolittle Library Schenectady County Historical Society 32 Washington Ave. -
Participant List
Participant List 10/20/2019 8:45:44 AM Category First Name Last Name Position Organization Nationality CSO Jillian Abballe UN Advocacy Officer and Anglican Communion United States Head of Office Ramil Abbasov Chariman of the Managing Spektr Socio-Economic Azerbaijan Board Researches and Development Public Union Babak Abbaszadeh President and Chief Toronto Centre for Global Canada Executive Officer Leadership in Financial Supervision Amr Abdallah Director, Gulf Programs Educaiton for Employment - United States EFE HAGAR ABDELRAHM African affairs & SDGs Unit Maat for Peace, Development Egypt AN Manager and Human Rights Abukar Abdi CEO Juba Foundation Kenya Nabil Abdo MENA Senior Policy Oxfam International Lebanon Advisor Mala Abdulaziz Executive director Swift Relief Foundation Nigeria Maryati Abdullah Director/National Publish What You Pay Indonesia Coordinator Indonesia Yussuf Abdullahi Regional Team Lead Pact Kenya Abdulahi Abdulraheem Executive Director Initiative for Sound Education Nigeria Relationship & Health Muttaqa Abdulra'uf Research Fellow International Trade Union Nigeria Confederation (ITUC) Kehinde Abdulsalam Interfaith Minister Strength in Diversity Nigeria Development Centre, Nigeria Kassim Abdulsalam Zonal Coordinator/Field Strength in Diversity Nigeria Executive Development Centre, Nigeria and Farmers Advocacy and Support Initiative in Nig Shahlo Abdunabizoda Director Jahon Tajikistan Shontaye Abegaz Executive Director International Insitute for Human United States Security Subhashini Abeysinghe Research Director Verite -
Sports Figures Price Guide
SPORTS FIGURES PRICE GUIDE All values listed are for Mint (white jersey) .......... 16.00- David Ortiz (white jersey). 22.00- Ching-Ming Wang ........ 15 Tracy McGrady (white jrsy) 12.00- Lamar Odom (purple jersey) 16.00 Patrick Ewing .......... $12 (blue jersey) .......... 110.00 figures still in the packaging. The Jim Thome (Phillies jersey) 12.00 (gray jersey). 40.00+ Kevin Youkilis (white jersey) 22 (blue jersey) ........... 22.00- (yellow jersey) ......... 25.00 (Blue Uniform) ......... $25 (blue jersey, snow). 350.00 package must have four perfect (Indians jersey) ........ 25.00 Scott Rolen (white jersey) .. 12.00 (grey jersey) ............ 20 Dirk Nowitzki (blue jersey) 15.00- Shaquille O’Neal (red jersey) 12.00 Spud Webb ............ $12 Stephen Davis (white jersey) 20.00 corners and the blister bubble 2003 SERIES 7 (gray jersey). 18.00 Barry Zito (white jersey) ..... .10 (white jersey) .......... 25.00- (black jersey) .......... 22.00 Larry Bird ............. $15 (70th Anniversary jersey) 75.00 cannot be creased, dented, or Jim Edmonds (Angels jersey) 20.00 2005 SERIES 13 (grey jersey ............... .12 Shaquille O’Neal (yellow jrsy) 15.00 2005 SERIES 9 Julius Erving ........... $15 Jeff Garcia damaged in any way. Troy Glaus (white sleeves) . 10.00 Moises Alou (Giants jersey) 15.00 MCFARLANE MLB 21 (purple jersey) ......... 25.00 Kobe Bryant (yellow jersey) 14.00 Elgin Baylor ............ $15 (white jsy/no stripe shoes) 15.00 (red sleeves) .......... 80.00+ Randy Johnson (Yankees jsy) 17.00 Jorge Posada NY Yankees $15.00 John Stockton (white jersey) 12.00 (purple jersey) ......... 30.00 George Gervin .......... $15 (whte jsy/ed stripe shoes) 22.00 Randy Johnson (white jersey) 10.00 Pedro Martinez (Mets jersey) 12.00 Daisuke Matsuzaka .... -
2017 Annual Report
2017 Annual Report Celebrating 113 Years ~ Serving Sailors, Marines, and their families 2017 OUR MISSION TABLE OF CONTENTS To provide, in partnership with the Navy and Marine Corps, financial, educational and other assistance to Greetings from the Secretary of the Navy ...............3 members of the Naval Service of the United States, their A Message from the Commandant of the eligible family members and survivors when in need; Marine Corps ...........................................................4 and to receive and manage funds to administer these programs. A Message from the Chief of Naval Operations ......5 President’s Year in Review......................................6 VISION Report of the Relief Committee ...............................7 As a non-profit, volunteer service organization, we Report of the Finance Committee............................8 use both financial and non-financial resources to Financial Position and Summary of Operations ......9 identify solutions to meet emerging needs. We help clients improve personal financial skills and encourage Financial Highlights ...............................................10 individual financial responsibility. A Comparison of Financial Assistance to Contributions .........................................................11 GUIDING PRINCIPLES Financial Assistance & Active Duty Fund Drive Results .................................................12 – 13 We provide effective client service in a consistent, compassionate, and non-judgmental manner. Volunteer Recognition ...........................................14