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UCLA MEDICAL DEVICE PARTNERING CONFERENCE © 2016 Regents of the University of California Contents INDUSTRY INVENTORS INVESTORS ONFER ERING C ENCE RTN PA 4TH ANNUAL ICE EV D AL IC ED M A TUESDAY MARCH 8, 2016 L C CNSI—UCLA CAMPUS U #UCLAMedDevice Conference Program 9:30 am REGISTRATION/NETWORKING 9:45 am WELCOME—Emily Waldron Loughran MORNING SESSION 10:00 am INVESTOR PANEL J&J Innovation | Life Science Angels | TitanMed Capital | Seroba Life Sciences | Enterprise Ireland | WSGR 11:15 am FACULTY PRESENTATIONS Kalyanam Shivkumar | Reggie Edgerton | Nader Pouratian | Jeffrey Ardell | Itzhak Fried 12:30 pm LUNCH AFTERNOON SESSION 1:30 pm INDUSTRY PANEL St. Jude Medical | SetPoint Medical | Action Potential | Boston Scientific | Medtronic | Allergan | RCT Ventures 2:45 pm UCLA BUSINESS OF SCIENCE CENTER 3:05 pm NETWORKING BREAK 3:30 pm UCLA STARTUP PITCHES HyTek Medical | KASH Scientific | Hypothermia Devices 4:00 pm NETWORKING/EVENT CLOSE B UCLA MEDICAL DEVICE PARTNERING CONFERENCE © 2016 Regents of the University of California Contents Speaker Profiles 2 Startup Company Profiles 9 UCLA Available Medical Device Technologies 10 Neuromodulation and Recording Technologies 11 Cardiovascular Devices 13 Device Materials 14 Diagnostic Tools 16 Orthopedic Devices and Biomechanics 16 Radiation Therapy and Oncology 17 Sensors and Patient Monitoring Devices 17 Surgical Tools 19 Conference Sponsors and Partner Organizations 21 Contact Information 22 Michael Ackermann, Ph.D. Jeffrey L. Ardell, Ph.D., Anthony Arnold Vice President, Neurostimulation FAHA President and CEO Allergan, Plc Professor of Medicine/Cardiology SetPoint Medical Director, UCLA Neurocardiology Research Center of Excellence UCLA Cardiac Arrhythmia Center Michael is currently Vice President, Dr. Ardell is the founding Director of the Tony is President and CEO of SetPoint Neurostimulation for Allergan, Plc, UCLA Neurocardiology Research Center Medical, an early stage medical and most recently CEO of Oculeve, of Excellence and on faculty in the UCLA device company developing a novel Inc., which was acquired by Allergan Cardiac Arrhythmia Center. Previously, implantable bioelectronic medicine in August 2015. He has eleven years he was Professor of Biomedical Sciences therapy to improve the lives of patients of experience in medical technology at the Quillen College of Medicine in with debilitating inflammatory diseases development in both academic and Johnson City, Tennessee. Dr. Ardell such as Crohn’s and rheumatoid arthritis. industrial settings in the fields of received his doctorate at the University Tony brings 18 years of experience in ophthalmology, chronic pain and of Washington, with post-doctoral the development and commercialization movement disorders. He received a B.E. training at Michigan State University and of high-tech medical devices. Prior to degree, magna cum laude, in biomedical at Loyola University of Chicago. He is a joining SetPoint, he founded Synapse engineering from Vanderbilt University, fellow of the American Heart Association Strategy and provided consulting M.S. and Ph.D. degrees in biomedical and is one of the principal investigators services for leading device firms, FDA engineering from Case Western Reserve in the field of neurocardiology. Dr. Ardell and professional organizations to help University, is a graduate of the Stanford has served on multiple national research commercialize products, develop public University Biodesign fellowship, and and advisory committees for the National health campaigns, assess opportunities Vision Research Fellow at Stanford. Institutes of Health and the American and develop strategic plans. Prior He has numerous patents and peer- Heart Association. to Synapse, Tony served as VP of reviewed publications. His laboratory has been at the forefront Marketing for Boston Scientific where in defining the neural circuits of the he launched the Harmony® Bionic Ear. cardiac nervous system in normal Tony was also Director of Marketing at and pathological states and how Medtronic, responsible for the industry they regulate cardiac electrical and leading StealthStation® neuro-navigation mechanical function. Recent work platform. Prior to Medtronic, Tony held from his group has demonstrated a variety of positions in marketing and that targeting select elements within R&D with Smith + Nephew. this neural network, using bioelectric Tony holds a Bachelors in Mechanical therapies, can lead to efficacious Engineering and graduated the UCLA results in select cardiac disease states, Anderson School of Management including atrial arrhythmias, myocardial executive program for medical marketing. infarction, and congestive heart failure. 2 4TH ANNUAL UCLA MEDICAL DEVICE PARTNERING CONFERENCE Allen W. Burton, M.D. Rafael Carbunaru, Ph.D. Roy Doumani Medical Director of Neuromodulation, Vice President, Executive Director, Movement Disorders and Pain Research & Development UCLA Business of Science Center VP of Clinical Affairs Boston Scientific Neuromodulation Professor, UCLA David Geffen St. Jude Medical School of Medicine Dr. Allen W. Burton is a Board- Rafael Carbunaru leads the Research Roy Doumani is a professor at the Certified Anesthesiologist, with added and Development Neuromodulation David Geffen School of Medicine at the Certification in Pain Medicine. He was Division for Boston Scientific University of California, Los Angeles formerly the Chairman of the Department Corporation located in Valencia, CA. (UCLA) and Executive Director of the of Pain Medicine at the University of He is focused on developing a portfolio UCLA Business of Science Center. He Texas MD Anderson Cancer Center of neuromodulation products and serves as Co-Chairman of the Zhejiang from 2000–2011. He helped train technologies, and creating a culture California NanoSystems Institute in the many pain fellows during that time. of meaningful innovation and high People’s Republic of China (PRC) and He then spent 4 years with Houston performance. His team has developed is a Director of the first joint venture Pain Associates, where he directed breakthrough products in spinal cord bank in the PRC, Xiamen International clinical research and participated in stimulation for the treatment of chronic Bank of which he has an equity position. many clinical trials. Dr. Burton joined pain and deep brain stimulation for Mr. Doumani has been involved with St. Jude Medical in September of 2015 movement disorders. Rafael’s mission numerous financial institutions: Director as Medical Director of Neuromodulation, is to transform lives through innovative of First Los Angeles Bank, Chairman of Movement Disorders and Pain, and VP of medical technologies. First Interstate Bank of Hawaii, Chairman Clinical Affairs. of World Trade Bank, Los Angeles, Prior to this role, Rafael was the Executive Director of HonFed Bank, Dr. Burton obtained his Bachelor of Research & Development Director and a Founder of Agensys, Inc. He is Science at the University of Notre Dame, for Emerging Indications. He led the presently Chairman of Neural Analytics Medical Doctorate at Baylor College development of micro stimulation and and a Founder and Director of Kite of Medicine, and residency at Brigham MRI-compatible technologies as well as Pharma. He earned a degree from and Women’s Hospital, Harvard Medical supported clinical trials in migraine and UCLA in Business and Finance and School. Dr. Burton has published more overactive bladder, among others. a law degree from the University of than 50 peer-reviewed articles in Rafael holds a Ph.D. and M.Sc. in Southern California. the pain literature and authored two Biomedical Engineering (with emphasis in textbooks. Dr. Burton teaches and neurostimulation and electromagnetism) lectures nationally and internationally. from Case Western Reserve University He has served in leadership roles and an Electrical Engineering degree in pain societies, and serves on from Universidad Simon Bolivar many editorial boards. His practice (Venezuela). He currently holds over 50 includes the use of pharmacologic, U.S. and International patents. interventional, and behavioral pain management techniques. Dr. Burton is an active researcher and has started a pharmaceutical company in the pain space, Vapogenix (www.vapogenix.com). Dr. Burton lives with his wife and three sons in Houston. He spends his small amount of free time running, cycling, swimming, and watching sports. 4TH ANNUAL UCLA MEDICAL DEVICE PARTNERING CONFERENCE 3 V. Reggie Edgerton, Ph.D. Jeffrey Erb Itzhak Fried, M.D., Ph.D., Distinguished Professor, UCLA Senior Director of Strategy, FACS Neurosurgery, Integrative Biology and Business Development and Professor, UCLA Neurosurgery Physiology, and Neurobiology Alliance Management Professor, UCLA Psychiatry and Director, UCLA Neuromuscular Medtronic PLC, Neuromodulation Biobehavioral Sciences Research Laboratory Member, UCLA Brain Research Institute Dr. V. Reggie Edgerton received his Jeff Erb is Senior Director of Itzhak Fried is the Director of the Ph.D. in Exercise Physiology from Strategy, Business Development and Adult Epilepsy Surgery Program in Michigan State University, Masters from Alliance Management for Medtronic the Department of Neurosurgery at University of Iowa and B.S. from East Neuromodulation. Jeff is responsible UCLA as well as the Co-Director of Carolina University. He is the Director of for leading portfolio strategy including the Seizure Disorder Center. The the Neuromuscular Research Laboratory the annual strategic planning process; epilepsy surgery program at UCLA is and Distinguished Professor of the identifying, investing in and acquiring
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