ISSN: 2475-5435

Case Rport International Journal of Gilles De La : A Case and A Brief Review of the Early Documentation of the Syndrome in The Literature

Aamir Jalal Al Mosawi* Senior Advisor Doctor, Baghdad Medical City, Head, Iraq Headquarter *Corresponding author of Copernicus Scientists International Panel, Baghdad, Iraq. Aamir Jalal Al Mosawi, Senior Advisor Doctor, Baghdad Medical City , Head, Iraq Headquarter of Copernicus Scientists International Panel, Baghdad, Iraq. Submitted: 12 Oct 2020; Accepted: 15 Nov 2020; Published: 26 Nov 2020

Abstract Background: Gilles de la Tourette syndrome is a neuro-psychiatric condition associated with rather bizarre manifestations and generally affects children with normal intelligence. The condition has the potential to make an intelligent child a victim of the disorder, and unfavorably affects his/her school performance and lead to social rejection and isolation. Awareness by the community, educators, and also medical practitioners is useful and help in avoiding the loss of such children who have the potential to be a talented person. The aim of this paper is to present a case and to provide a brief account on the early documentation of syndrome in the literature. Patients and Methods: The case of a ten-year old boy with Gilles de la Tourette syndrome is described and the relevant literatures were reviewed to outline the early documentation of the disorder in the literature. Results: A.Y was first seen at the pediatric psychiatric clinic of the Children Teaching Hospital of Baghdad Medical City at the age of ten years because they were saying at school that the boy is crazy because of his abnormal behaviors. The boy’s abnormal behaviors mentioned by his mother included shrugging his shoulders, shrugging his hips with unusual movements of the legs as if he was dancing, unusual facial grimace and lip licking, rubbing his chin, licking the back of his hand, producing abnormal sounds from his throat, and . Review of the earliest relevant literature revealed that the condition was first described in a book entitled “Malleus Maleficarum” which means “Witch’s hammer”. , a French doctor described the first case of Tourette syndrome in 1825. Conclusion: Awareness of this condition by the community, educators, and also medical practitioners is useful and help in avoiding the loss of such children who have the potential to be a talented person.

Keywords: Awareness, Early documentation, Gilles de la Tourette Patients and Methods syndrome, Literature. The case of a ten-year old boy with Gilles de la Tourette syndrome is described and the relevant literatures were reviewed to outline Introduction the early documentation of the disorder in the literature. Gilles de la Tourette syndrome is a pediatric neuro-psychiatric condition generally affecting children with normal intelligence, Results and may affect also talented children. The rather bizarre A.Y was first seen at the pediatric psychiatric clinic of the Children manifestations of the syndrome including involuntary movements Teaching Hospital of Baghdad Medical City at the age of ten years and utterances may make an intelligent child a victim of the because they were saying at school that the boy is crazy because of disorder, and unfavorably affects his/her school performance and his abnormal behaviors. The parents were unrelated. The father lead to social rejection and isolation. Awareness of this condition was a forty-year old porter, and his education was limited to by the community, educators, and also medical practitioners is finishing fifth grade of primary school. The mother aged thirty and useful and help in avoiding the loss of such children who have the her education was limited to finishing third grade of intermediate potential to be talented persons [1, 2]. The aim of this paper is to school. The boy had an older healthy sister aged fifteen years and present a case and to provide a brief account on the early an older healthy brother aged thirteen, they were studying at third documentation of syndrome in the literature. grade and first grade of intermediate school respectively. Int J Psychiatry 2020 www.opastonline.com Volume 5 | Issue 3 | 1 The boy was studying at 4th grade of primary school and his Review of the earliest relevant literature revealed that the condition school performance was considered acceptable. At the pediatric was first described in a book entitled “Malleus Maleficarum” psychiatry clinic, the mother the child was whispering to the (Figure 2) which means “Witch’s hammer”. mother asking her not to say certain things, and the mother appeared to hide some embarrassing behaviors of her son. The book was written by Jakob Sprenger and Heinrich Kraemer, However, the boy’s abnormal behaviors mentioned by his mother and was published in the late 15th century. The book described a included: priest whose were considered to be related to possession by the devil”. Shrugging his shoulders. Jean Marc Gaspard Itard (Figure 3), a French doctor described the Shrugging his hips with unusual movements of the legs as if he first case of Tourette syndrome in 1825. He described a female was dancing. patient, Marquise de Dampierre who was a distinguished woman Unusual facial grimace and lip licking. of nobility in her time. Rubbing his chin. Licking the back of his hand. Producing abnormal sounds from his throat. Echolalia which is repeating some words he was hearing.

The parent was reproaching the boy and asking him to stop doing these behaviors, but in vain. The child was obviously embarrassed from these behaviors and was trying to avoid talking about them, but he confirmed that he cannot stop them. The boy has been experiencing these abnormal behaviors for more than one year.

At the clinic the child was cooperative and responsive, but he was obviously trying to avoid talking about his abnormal behaviors because of embarrassment. The child was convinced to show some of the abnormal movements and he showed how the involuntary movements of rubbing his chin (Figure-1).

Figure 2: The syndrome was first described in a book entitled “Malleus Maleficarum”

Figure 1: At the clinic the child was cooperative and responsive, ad was convinced to show some of the abnormal movements, and he showed how the involuntary movements of rubbing his chin

As Haloperidol was the most commonly used medication to treat Gilles de la Tourette syndrome (Bixby,1970; Healy,1970; Nishiura and Hirota,1970; Shapiro, 1970) [1], the child was treated with haloperidol in initial dose of 0.5 mg daily, increased to 1mg daily within a week. Haloperidol was successful in reducing the child s Figure 3: Jean Marc Gaspard Itardm (1774-1838), a French symptoms. physician who

Int J Psychiatry 2020 www.opastonline.com Volume 5 | Issue 3 | 2 During the years 1984, 1885, and 1899, Georges Gilles de la In fact, Jean-Martin Charcot who was influential French physician Tourette (Figure-4), [Gilles de la Tourette. Arch, de Neur, 1884; assigned himself his resident Georges Albert Édouard Brutus Gilles de la Tourette. Arch, de Neur, 1885; Gilles de la Tourette. Gilles de la Tourette, the duty of studying the patients at the Semaine Medicale, 1899] described nine patients having sporadic Hospital universities Pitié-Salpêtrière. Their aim was to define the condition Maladie des tics convulsifs.” condition and make it distinctive from hysteria and from chorea [1, 3].

One of the patients described by Gilles de la Tourette’s description was a seven-year old child who exhibited a series of tics. The twitches were initially confined to the facial musculature with later appearance of vocal tics as expiratory laryngeal noises such as hems and ahs and gradually the abnormal movements involved the shoulders and arms. Gilles de la Tourette emphasized that the manifestation of the disorder may be limited to abnormal facial movements for several months or years before the development of the inarticulate laryngeal sounds [1-3].

In 1968, Arthur K Shapiro, treated a patient having Gilles de la Tourette syndrome with haloperidol, and published a paper criticizing the psychoanalytic approach. The contributions of Shapiro improved the understanding of the syndrome, and completely changed the prevailing view of the condition [4].

Figure 4: Georges Albert Édouard Brutus Gilles de la Tourette Discussion (1857-1904), a French physician and neurologist Children with Gilles de la Tourette syndrome can be faster than the average for their age group on timed tests of motor coordination. Jean-Martin Charcot (Figure-5), a French neurologist and authored a book with Ali Benjamin entitled “The professor trained Gilles de la Tourette. He called the condition Keeper: A Life of saving goals and achieving them”. He described Tourette syndrome after his resident, Georges Gilles de la Tourette his career and his life with Gilles de la Tourette syndrome. Howard and suggested that a new clinical category should be defined [1, 3]. thought that his neurological structure gave him an enhanced perception and ability to hyper-focus that contributed to his success on the field of football.

Conclusion Awareness of this condition by the community, educators, and also medical practitioners is useful and help in avoiding the loss of such children who have the potential to be a talented person.

Acknowledgement 1. The author would like to express his gratitude for the patient of the patient for willingly accepting publishing his photos. 2. Some of the sketches were included in some of the author’s publications, but the author has their copyright.

References 1. Gilles de la Tourette G, Goetz CG, Llawans HL, trans (1982) Étude sur une affection nerveuse caractérisée par de l’incoordination motrice accompagnée d’echolalie et de coprolalie. In: Friedhoff AJ, Chase TN, eds. Advances in Figure 5: Jean-Martin Charcot (1825-1893), a French Neurology, Gilles de la Tourette syndrome. New York: Raven neurologist Press 35: 1-16.

Int J Psychiatry 2020 www.opastonline.com Volume 5 | Issue 3 | 3 2. Al Mosawi AJ (2018) Gilles de La Tourette syndrome. 1st ed., 4. Shapiro AK, Shapiro E (1968) Treatment of Gilles de la Saarbrücken; LAP Lambert Academic Publishing: 2018 Tourette’s Syndrome with haloperidol. Br J Psychiatry 114: (ISBN: 978-613-9-84376-3). 345-350. 3. Teive HA, Chien HF, Munhoz RP, Barbosa ER (2008) Charcot’s contribution to the study of Tourette’s syndrome. Arq Neuropsiquiatr 66: 918-921. PMID: 19099145.

Copyright: ©2020 Aamir Jalal Al Mosawi. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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