DOCSLIB.ORG

Redalyc. a Closer Look at the History and Genetics of Tourette Syndrome

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Redalyc. a Closer Look at the History and Genetics of Tourette Syndrome Salud Mental Instituto Nacional de Psiquiatría Ramón de la Fuente [email protected] ISSN (Versión impresa): 0185-3325 MÉXICO 2008 Adriana Díaz Anzaldúa / Guy A. Rouleau A CLOSER LOOK AT THE HISTORY AND GENETICS OF TOURETTE SYNDROME Salud Mental, marzo-abril, año/vol. 31, número 002 Instituto Nacional de Psiquiatría Ramón de la Fuente Distrito Federal, México pp. 103-110 Red de Revistas Científicas de América Latina y el Caribe, España y Portugal Universidad Autónoma del Estado de México http://redalyc.uaemex.mx Salud Mental 2008;31:103-110 History and genetics of Tourette syndrome A closer look at the history and genetics of Tourette syndrome Adriana Díaz-Anzaldúa,1 Guy A. Rouleau2 Artículo original SUMMARY functioning of the patients. With respect to the age of onset, the ICD- 10 Classification of Mental and Behavioural Disorders describes the Tourette syndrome (TS) was named after Georges Albert Edouard onset almost always in childhood or adolescence, and in this way it Brutus Gilles de la Tourette, who made its first formal description at would no longer exclude cases with later onset. Numerous studies the end of the 19th century. Nevertheless, some evidence indicates the confirmed in the 20th century that genetics plays an important role in disorder may have been recognised at least two thousand years ago. the etiology of TS. Family studies proved that the disease runs in Tic like behaviours were recorded by Aretaeus of Cappadocia and families. First-degree relatives of TS patients are indeed in greater several centuries later by Sprenger and Kraemer, followed by other risk for TS than the general population. Twin and adoption studies descriptions. The English writer Samuel Johnson, author of the first demonstrated that genes have an important role in the etiology of TS, English Language Dictionary, showed repetitive body twitches, facial and as much as 90% of the vulnerability to this syndrome could be grimaces, barks and grunts, among other tics. He was observed in affected by genes. In addition, environmental, epigenetic and even situations such as going in or out at a door using a certain number of stochastic factors may affect the susceptibility to TS. steps, from a certain point, which indicated he had also obsessive- At the molecular level, linkage in families and association in compulsive behaviour. There was some evidence of features of TS as unrelated TS subjects have been the main methods used to search for well as co-morbid conditions such as hyperactivity, obsessive- vulnerability genes. Sequencing of almost the entire human genome compulsive behaviour or rage attacks in other famous artists and world made it possible to assess the gene expression of thousands of genes leaders. Some authors have even proposed that the creative, on a single chip; recent studies reported a preliminary specific profile determined, competitive, and persistent nature of certain people may in the blood of TS patients. If confirmed, this finding could be useful in be related to the presence of TS. the identification of genetic factors related with TS. Clinicians have observed that some patients are particularly Given the multi-factorial nature of TS, a thorough clinical sensitive to the feelings and experiences of others, and more prone to description in large samples should be considered; besides association, outside stimuli. In this way, empathy could be a common quality in linkage and sequencing studies, possible gene-gene and gene- these patients. In 1825, Jean Marc Gaspard Itard made the first known environment interactions would also need to be analysed, as well as medical description of TS based on two cases, one of which was later epigenetic factors, and gene expression patterns. followed by Jean-Martin Charcot. In 1885 Gilles de la Tourette put together information from previous fragmented reports and wrote a Key words: Tourette syndrome, Gilles de la Tourette syndrome, complete and formal description, thus establishing a novel clinical Georges Gilles de la Tourette, genetics of Tourette syndrome, tic entity. Behavioural abnormalities such as obsessions, compulsions, disorder. inattentiveness and hyperactivity, commonly observed in TS patients, were considered mental tics at the time. Current diagnostic criteria are very similar to Gilles de la Tourette’s description. TS is characterized RESUMEN by the presence of multiple motor and one or more vocal tics. In this disorder, tics are not caused by the direct physiologic effects of a El síndrome de Gilles de la Tourette (SGT) se nombró asi en honor de substance or a general medical condition. Tic symptomatology is Georges Albert Edouard Brutus Gilles de la Tourette, alumno de persistent for over a year, and in this period, tics are not absent for Charcot, quien realizó la primera descripción formal de esta entidad more than three consecutive months. clínica a finales del siglo XIX. Sin embargo, hay evidencias que indican There is no exact consensus between the DSM-IV and the Tourette que probablemente el trastorno se había identificado de alguna Syndrome Classification Study Group of whether the age of onset manera desde hace por lo menos dos mil años. Areteo de Capadocia should be prior to 18 or 21 years of age, how cases of onset after 21 registró conductas similares a los tics, también descritas por Sprenger years should be diagnosed, and if marked distress or significant y Kraemer en el siglo XV y más adelante por otros. El escritor inglés impairment caused by tics is necessary to define the condition as Samuel Johnson, autor del primer Diccionario de la Lengua Inglesa, definite TS. However, the text revision of the DSM-IV (TR) no longer mostraba contorsiones en todo el cuerpo, muecas, ladridos y gruñidos, specifies that TS symptoms have to cause distress or impair the entre otros tics. Se le observaba entrando o saliendo por una puerta 1 Departamento de Genética, Instituto Nacional de Psiquiatría Ramón de la Fuente, Calz. México-Xochimilco 101, San Lorenzo Huipulco, Tlalpan, 14370, México, D. F. E-mail Adriana Díaz Anzaldúa [email protected], Fax: 5513-3722. 2 Guy A. Rouleau, M.D., Ph.D., F.R.C.P.(C). Centre for the Study of Brain Diseases,CHUM Research Centre Notre Dame Hospital, J.A. de Sève Pavillion, Room Y-3633, 1560 Sherbrooke Street East, Montreal, QC H2L 4M1, Canada. Recibido: 9 de octubre de 2007. Aceptado: 5 de diciembre de 2007. Vol. 31, No. 2, marzo-abril 2008 103 Díaz Anzaldúa y Rouleau con un número determinado de pasos a partir de un punto dado, lo incapacidad en el funcionamiento diario de los pacientes. En cuanto cual indica que también presentaba conducta obsesivo- compulsiva. a la edad de inicio, si la Clasificación de los Trastornos Mentales y de Además, otros artistas y líderes mundiales han presentado la Conducta (CIE-10) describe que la edad de inicio casi siempre es características del SGT y de padecimientos comórbidos como el en la niñez o adolescencia, de esta manera ya no excluye la posibilidad trastorno por déficit de atención e hiperactividad, el trastorno obsesivo- de edades de inicio más avanzadas. compulsivo o ataques de ira. Un grupo de autores ha llegado a Gracias a diversos estudios, durante el siglo XX se pudo confirmar considerar que la naturaleza creativa, determinada, competitiva y que la genética es decisiva en la etiología del SGT. Por medio de estudios persistente en ciertas personas podría relacionarse con el SGT. Algunos en familias se confirmó que el trastorno se concentra particularmente especialistas del área médica han observado que ciertos pacientes en ciertas familias. Los parientes en primer grado de un paciente con con SGT son particularmente sensibles a los sentimientos y SGT se encuentran en mayor riesgo de presentar el trastorno que la experiencias de otras personas y más propensos a los estímulos población en general. Estudios realizados en pares de gemelos y externos. Por lo tanto, la empatía podría ser una cualidad común en personas adoptadas confirmaron que los genes tienen un peso estos pacientes. importante en el aumento de la susceptibilidad al SGT. Se ha estimado En 1825, Jean Marc Gaspard Itard realizó la primera descripción que hasta 90% de la vulnerabilidad al trastorno podría estar afectada médica conocida del SGT, basándose en dos casos, uno de los cuales por los genes. Aunados a estos factores hereditarios que dependen fue estudiado más adelante por Charcot. En 1885, Gilles de la Tourette directamente de la secuencia del ADN de nuestras células nucleadas, reunió fragmentos de información de reportes previos y redactó una se encuentran otros factores que afectan en cierto grado la susceptibilidad descripción formal y completa del trastorno, con lo que estableció al SGT, como los de tipo ambiental, epigenético o aleatorio. una nueva entidad clínica. Las anormalidades del tipo de obsesiones, A nivel molecular, los principales diseños para el estudio del compulsiones, inatención e hiperactividad se consideraban tics SGT y la búsqueda de genes de susceptibilidad han sido el enlace mentales en esa época. Los criterios diagnósticos actuales del SGT genético (linkage) en familias y los estudios de asociación en pacientes son muy similares a los publicados por Gilles de la Tourette. El SGT no emparentados. La secuenciación de prácticamente todo el genoma se caracteriza sobre todo por la presencia de dos o más tics motores humano ha permitido, entre otras cosas, identificar la expresión de y uno o más tics fónicos. En este trastorno, los tics no son causados miles de genes en un solo chip. De acuerdo con estudios preliminares por el efecto fisiológico directo de una droga o por una affeción recientes, podría haber un patrón específico de expresión en sangre médica general. La sintomatología de los tics persiste por más de un de pacientes con SGT. Si esto se llegara a confirmar, los hallazgos año y en este periodo los tics no se ausentan por más de tres meses podrían emplearse para facilitar la identificación de factores genéticos consecutivos.
Load more

Recommended publications
  • Neurosurgical Strategies for Gilles De La Tourette's Syndrome
    REVIEW Neurosurgical strategies for Gilles de la Tourette’s syndrome Karim Mukhida1,2 Abstract: Tourette’s syndrome (TS) is a neurological disorder characterized by motor and vocal Matthew Bishop2 tics that typically begin in childhood and often are accompanied by psychiatric comorbidities. Murray Hong2 Symptoms of TS may be socially disabling and cause secondary medical complications. Pharma- Ivar Mendez2 cological therapies remain the mainstay of symptom management. For the subset of patients in whom TS symptoms are medically recalcitrant and do not dissipate by adulthood, neurosurgery 1Division of Neurosurgery, University of Toronto, Toronto, may offer an alternative treatment strategy. Greater understanding of the neuroanatomic and Ontario, Canada; 2Departments pathophysiologic basis of TS has facilitated the development of surgical procedures that aim of Anatomy and Neurobiology to ameliorate TS symptoms by lesions or deep brain stimulation of cerebral structures. Herein, and Surgery (Neurosurgery), Dalhousie University, Halifax, the rationale for the surgical management of TS is discussed and neurosurgical experiences Nova Scotia, Canada since the 1960s are reviewed. The necessity for neurosurgical strategies to be performed with appropriate ethical considerations is highlighted. Keywords: tourette’s syndrome, neurosurgery, deep brain stimulation, thalamus Introduction Historical perspective In 1825, Jean-Marc Gaspard Itard, the Chief Physician at the National Institute for Deaf Mutes in Paris, provided careful clinical observations of stereotypic movements and vocalizations in the 26-year-old Marquise de Dampierre: [she] began to have convulsive contractions in her hand and arm muscles, which manifested themselves especially at the moments in which this [woman as a] child tried to write as she spread her hand over the characters that she traced.
    [Show full text]
  • Behavioral Therapies for Tourette Syndrome
    Psychological Disorders Tourette Syndrome PD Autism_F.indb 1 9/23/09 12:27:16 PM Psychological Disorders Addiction Alzheimer's Disease and Other Dementias Anxiety Disorders Attention-Deficit/Hyperactivity Disorder Autism Child Abuse and Stress Disorders Cutting and Self-Harm Depression and Bipolar Disorders Eating Disorders Impulse Control Disorders Personality Disorders Schizophrenia Sleep Disorders Suicide Tourette Syndrome PD Autism_F.indb 2 9/23/09 12:27:19 PM Psychological Disorders Tourette Syndrome M. Foster Olive, Ph.D. Series Editor Christine Collins, Ph.D. Research Assistant Professor of Psychology Vanderbilt University Foreword by Pat Levitt, Ph.D. Director, Vanderbilt Kennedy Center for Research on Human Development PD Autism_F.indb 3 9/23/09 12:27:23 PM Tourette Syndrome Copyright © 2010 by Infobase Publishing All rights reserved. No part of this book may be reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, or by any information storage or retrieval systems, without permission in writing from the publisher. For information contact: Chelsea House An imprint of Infobase Publishing 132 West 31st Street New York NY 10001 Library of Congress Cataloging-in-Publication Data Olive, M. Foster. Tourette syndrome / M. Foster Olive ; consulting editor, Christine Collins ; foreword by Pat Levitt. p. cm. — (Psychological disorders) Includes bibliographical references and index. ISBN-13: 978-1-60413-426-1 (hardcover : alk. paper) ISBN-10: 1-60413-426-7 (hardcover : alk. paper) ISBN-13: 978-1-4381-3072-9 (e-book) 1. Tourette syndrome. I. Collins, Christine E. (Christine Elaine) II. Title. III. Series. RC375.O45 2010 616.8’3—dc22 2009024427 Chelsea House books are available at special discounts when purchased in bulk quantities for businesses, associations, institutions, or sales promotions.
    [Show full text]
  • El Trastorno De Tourette a Lo Largo De La Historia Revista De La Asociación Española De Neuropsiquiatría, Vol
    Revista de la Asociación Española de Neuropsiquiatría ISSN: 0211-5735 [email protected] Asociación Española de Neuropsiquiatría España CARMONA FERNÁNDEZ, CRISTINA; ARTIGAS PALLARÉS, JOSEP El trastorno de Tourette a lo largo de la historia Revista de la Asociación Española de Neuropsiquiatría, vol. 36, núm. 130, julio-diciembre, 2016, pp. 347-362 Asociación Española de Neuropsiquiatría Madrid, España Disponible en: http://www.redalyc.org/articulo.oa?id=265048580004 Cómo citar el artículo Número completo Sistema de Información Científica Más información del artículo Red de Revistas Científicas de América Latina, el Caribe, España y Portugal Página de la revista en redalyc.org Proyecto académico sin fines de lucro, desarrollado bajo la iniciativa de acceso abierto R . A . E. N . ; ():- : ./S- El trastorno de Tourette a lo largo de la historia Tourette’s disorder in history CRISTINA CAR MONA F ERNÁNDEZ a,b , J OSEP ARTIGAS PALLARÉS a (a) Centre Mèdic Psyncron, Sabadell, Barcelona, España (b) Fundació Tourette, Barcelona, España. Correspondencia: Cristina Carmona Fernández ([email protected]) Recibido: 10/12/2015; aceptado con modificaciones: 31/05/2016 Resumen: El término trastorno de Tourette emerge en el campo de la psiquiatría con la aparición de la tercera edición del Manual Diagnóstico y Estadístico de Trastornos Menta - les (DSM-III) en el año 1980. Sin embargo, el hecho de que se consensuaran sus criterios diagnósticos por el grupo de expertos responsable de la elaboración de dicha versión del DSM no implica que previamente no existieran múltiples referencias a su sintomatología. El objetivo de este trabajo es recoger aportaciones de la historia de la neurología y de la psiquiatría que permitan comprender cómo se ha ido configurando el concepto operativo de trastorno de Tourette tal como es aceptado en la actualidad por una gran parte de la comunidad científica.
    [Show full text]
  • TOURETTE's Kathleen Weatherspoon [email protected]
    Murray State's Digital Commons Integrated Studies Center for Adult and Regional Education Fall 2017 TOURETTE'S kathleen weatherspoon [email protected] Follow this and additional works at: https://digitalcommons.murraystate.edu/bis437 Recommended Citation weatherspoon, kathleen, "TOURETTE'S" (2017). Integrated Studies. 115. https://digitalcommons.murraystate.edu/bis437/115 This Thesis is brought to you for free and open access by the Center for Adult and Regional Education at Murray State's Digital Commons. It has been accepted for inclusion in Integrated Studies by an authorized administrator of Murray State's Digital Commons. For more information, please contact [email protected]. Running head: TOURETTES 1 Tourette’s Kathleen Weatherspoon Murray State University TOURETTES 2 Table of Contents A. Introduction B. When and where Tourette’s was found in the United States. C. Diagnosis 1. Medicines 2. Male or Female and Age of Onset 3. Therapy 4. Treatment D. Different Types of Tic’s 1. Motor 2. Vocal E. Tests F. Bullying G. Clinic’s H. Famous People with Tourette’s I. Conclusion TOURETTES 3 Introduction What is Tourette’s and how does it affect the people? I will be talking about the different things that come along with Tourette’s and how it can be treated and what tics someone might have if diagnosed with Tourette’s. Tourette’s is a problem with the nervous system that causes people to make sudden movements or sounds, which are called tics that they can’t control in the body. Tics that come along with having Tourette’s can be serve and painful but can also be mild at times.
    [Show full text]
  • Chapter 1: the Nature of Tics and Habits: a Cognitive
    9 1 The Nature of Tics and Habits ­Overview of the Nature of Tics and Habits History The first references to tics go back to medieval times. In the fifteenth century, two Dominican monks reported the case of a priest who could not help but gri- mace and emit vocalizations, whenever he was praying (Kramer and Sprenger, 1948). Later in 1825, Jean-Marc Gaspard Itard described tics in a sys- tematic way for the first time (Itard, 1825). The latter reports the case of a 26-year-old French noblewoman, the Marquise de Dampierre, who presented involuntary convulsive spasms and contortions at the level of the shoulders, neck, and face. Shortly afterwards, he also reported the presence of “spasms affecting the organs of voice and speech,” and notes the presence of strange screams and senseless words in the absence of a circumscribed mental disorder. The Gilles de la Tourette syndrome is named after the French neurologist Georges Gilles de la Tourette, who, in 1885, described again the condition of the Marquise de Dampierre, now aged 86 years old, who continued to make abrupt movements and sounds also known as tics. The same year, Tourette described eight other patients with motor and vocal tics, some of whom had echo phenom- ena (a tendency to repeat things said to them) and coprolalia (utterances of obscene phrases) (Gilles de la Tourette, 1885) which was consistent with similar observations from American clinicians 1 year later (see Dana & Wilkin, 1886). In a doctoral dissertation published under the supervision of Tourette and Charcot, Jacques Catrou, documented 26 other cases (Catrou, 1890) with more details.
    [Show full text]
  • 淺談妥瑞（土瑞/杜雷特）症候群（Tourette Syndrome）
    淺談妥瑞（土瑞/杜雷特）症候群 （Tourette Syndrome） 羅湘敏 國立屏東師範學院特殊教育學系副教授 「班卡爾時不時會伸手向下一戮，或 婚時，她已經出現強迫性誓語（swear 是往上一刺，臉部肌肉常常不由自主 words）的行為，這種行為讓她難以被 地抽搐著，是個典型的杜氏症患者； 她社交圈的朋友接受，因此她終其一 彷彿受到鬼怪附身一般，病魔促使他 生都隱居某處（Carroll & Robertson, 必須立即釋放心中的衝動；令人驚訝 2000；Walter & Carter, 1997）。但一直 的是，他竟是一位優秀的，頗受病人 到 1885 年妥瑞醫生（Gilles de la 愛戴的外科醫生。許多杜氏症患者只 Tourette）在神經醫學雜誌 Archives de 想自人群中退縮，隱匿，班卡爾卻不 Neurologie 發表文章，描述了九位妥瑞 斷與心魔搏鬥，勇敢地面對人生，擁 症個案，其中六位是他自己的病患， 抱人群。除了穩穩掌握住手術刀，他 三位是其他醫師的病例(包括 Marquise 甚至能夠開飛機，在無盡的穹蒼中遨 de Dampierre)，這些患者主要徵狀為多 遊，活出開闊的自我。」（趙永芬譯， 重抽動（multiple tics）、迴語 民 85，104 頁） （echolalia）、和穢語（coprolalia）， 由 於妥瑞醫生的研究，遂以他的姓氏 妥瑞症是一種神經性疾病，主要 （Tourette）命 名（ Carroll & Robertson, 徵狀是不自主的動作/運動(movement) 2000）。 和聲語/發聲(voice)tic，tic 是一種突發 的、快速的、重複發生的、非韻律性 壹、出現率 的、刻板的動作和/或發聲（孔繁鐘, 民 86）。早在十五世紀時，Sprenger 和 從妥瑞醫師 1885 年發表文章後到 Kraemer 描述了一位有動作和聲語 tic 1960 年代間，文獻上妥瑞症的病例不 的牧師被成功驅魔的記載（Shapiro & 到百位，因此早期認為妥瑞症是一種 Shapiro, 1982）。而音樂神童莫扎特的 罕見病症。但從 1970 年代起，越來越 行為舉止和書信中猥褻的辭句也讓人 多妥瑞症病患被診斷出來（Walter & 認為他是妥瑞症（Simkin, 1992）。 一 八 Carter, 1997）。但是由於多數輕度和中 二五年有特殊教育之父之稱的伊達醫 度妥瑞症患者可能忽略而未被診斷， 生（ Jean Marc Gaspard Itard）報告了一 有些患者也可能被診斷為其他病症， 位法國貴婦 Marquise de Dampierre，她 如注意力缺陷過動症、強迫症等，因 在七歲時就出現了 tics 的症狀，當她結 此實際的盛行率可能仍然偏低。一般 1 言，妥瑞症的出現率在 些活動時又可能不出現。在某時出現 1/10,000~12/10,000 間（Bagheri, 某些 tics，隔段時間後又出現其他 Kerbeshian, & Burd, 1999; King & tics(Bronheim, 1991)。目前精神醫學上 Ollendick, 1984; Walter & Carter, 的診斷也以 tic 為主要的診斷參考標 1997），美國精神醫學學會心智疾患診 準，如美國精神醫學心智疾患診斷與 斷與統計手冊第四版估計每萬人中約 統計手冊第四版對妥瑞症的診斷標準 有四至五患者（孔繁鐘, 民 86）， 但 也 如下： 有研究顯示青少年的出現率可能高達 一、在發病期間，同期間出現多種動 31/1,000~157/1,000（Hornsey, Banerjee, 作和一種或一種以上聲語的
    [Show full text]
  • An Epidemiological Study of Adolescent Psychopathology and Gilles De La Tourette Syndrome in West Essex
    AN EPIDEMIOLOGICAL STUDY OF ADOLESCENT PSYCHOPATHOLOGY AND GILLES DE LA TOURETTE SYNDROME IN WEST ESSEX Heatha Amanda Karen Hornsey Thesis submitted for the degree of Doctor of Philosophy to the Faculty of Clinical Science, University of London Department of Psychiatry and Behavioural Sciences University Coiiege London 2003 ProQuest Number: U644013 All rights reserved INFORMATION TO ALL USERS The quality of this reproduction is dependent upon the quality of the copy submitted. In the unlikely event that the author did not send a complete manuscript and there are missing pages, these will be noted. Also, if material had to be removed, a note will indicate the deletion. uest. ProQuest U644013 Published by ProQuest LLC(2016). Copyright of the Dissertation is held by the Author. All rights reserved. This work is protected against unauthorized copying under Title 17, United States Code. Microform Edition © ProQuest LLC. ProQuest LLC 789 East Eisenhower Parkway P.O. Box 1346 Ann Arbor, Ml 48106-1346 Abstract ABSTRACT The principal aims of this study were threefold. Firstly, the study set out to estimate the prevalence of mental health problems in a population of 13-14 year old adolescents attending mainstream secondary schools in West Essex. Using a cross-sectional methodology, standardised screening questionnaires were used to identify the presence of specific disorders, based on information from parents, teachers and adolescents. Comparisons were made between those who were and were not referred for treatment. Secondly, a three-stage ascertainment procedure was embedded in the study methodology to determine the prevalence of Gilles de la Tourette Syndrome (TS) in the same population.
    [Show full text]
  • Gilles De La Tourette Syndrome: a Case and a Brief Review of the Early Documentation of the Syndrome in the Literature
    ISSN: 2475-5435 Case Rport International Journal of Psychiatry Gilles De La Tourette Syndrome: A Case and A Brief Review of the Early Documentation of the Syndrome in The Literature Aamir Jalal Al Mosawi* Senior Advisor Doctor, Baghdad Medical City, Head, Iraq Headquarter *Corresponding author of Copernicus Scientists International Panel, Baghdad, Iraq. Aamir Jalal Al Mosawi, Senior Advisor Doctor, Baghdad Medical City , Head, Iraq Headquarter of Copernicus Scientists International Panel, Baghdad, Iraq. Submitted: 12 Oct 2020; Accepted: 15 Nov 2020; Published: 26 Nov 2020 Abstract Background: Gilles de la Tourette syndrome is a neuro-psychiatric condition associated with rather bizarre manifestations and generally affects children with normal intelligence. The condition has the potential to make an intelligent child a victim of the disorder, and unfavorably affects his/her school performance and lead to social rejection and isolation. Awareness by the community, educators, and also medical practitioners is useful and help in avoiding the loss of such children who have the potential to be a talented person. The aim of this paper is to present a case and to provide a brief account on the early documentation of syndrome in the literature. Patients and Methods: The case of a ten-year old boy with Gilles de la Tourette syndrome is described and the relevant literatures were reviewed to outline the early documentation of the disorder in the literature. Results: A.Y was first seen at the pediatric psychiatric clinic of the Children Teaching Hospital of Baghdad Medical City at the age of ten years because they were saying at school that the boy is crazy because of his abnormal behaviors.
    [Show full text]
  • El Trastorno De Tourette a Lo Largo De La Historia
    Rev. Asoc. Esp. Neuropsiq. 2016; 36(130):347-362 doi: 10.4321/S0211-57352016000200004 El trastorno de Tourette a lo largo de la historia Tourette’s disorder in history CRISTINA CARMONA FERNÁNDEZa,b, JOSEP ARTIGAS PALLARÉSa (a) Centre Mèdic Psyncron, Sabadell, Barcelona, España (b) Fundació Tourette, Barcelona, España. Correspondencia: Cristina Carmona Fernández ([email protected]) Recibido: 10/12/2015; aceptado con modificaciones: 31/05/2016 Resumen: El término trastorno de Tourette emerge en el campo de la psiquiatría con la aparición de la tercera edición del Manual Diagnóstico y Estadístico de Trastornos Menta- les (DSM-III) en el año 1980. Sin embargo, el hecho de que se consensuaran sus criterios diagnósticos por el grupo de expertos responsable de la elaboración de dicha versión del DSM no implica que previamente no existieran múltiples referencias a su sintomatología. El objetivo de este trabajo es recoger aportaciones de la historia de la neurología y de la psiquiatría que permitan comprender cómo se ha ido configurando el concepto operativo de trastorno de Tourette tal como es aceptado en la actualidad por una gran parte de la comunidad científica. En la última década, merced a los estudios de asociación de todo el genoma, se han producido importantes avances en la identificación de variantes comu- nes y variantes raras implicadas en la etiología del trastorno de Tourette. La conclusión más relevante que se desprende de esta revisión es poner al descubierto la crisis del modelo categórico kraepeliniano del trastorno. Palabras clave: síndrome de Tourette, trastorno de Tourette, enfermedad de Gilles de la Tourette, Manual Diagnóstico y Estadístico de los Trastornos Mentales (DSM), tics, CIE (Clasificación Internacional de Enfermedades).
    [Show full text]
  • School Psychologists' Training and Knowledge of Tourette Syndrome
    Chapman University Chapman University Digital Commons Educational Studies Dissertations Summer 8-2015 School Psychologists’ Training and Knowledge of Tourette Syndrome Leticia Cornejo Chapman University, [email protected] Follow this and additional works at: https://digitalcommons.chapman.edu/ces_dissertations Part of the Accessibility Commons, Child Psychology Commons, Educational Assessment, Evaluation, and Research Commons, Educational Psychology Commons, Other Psychology Commons, and the School Psychology Commons Recommended Citation Cornejo, L. (2015). School psychologists’ training and knowledge of Tourette syndrome (Doctoral dissertation). https://doi.org/10.36837/chapman.000028 This Dissertation is brought to you for free and open access by Chapman University Digital Commons. It has been accepted for inclusion in Educational Studies Dissertations by an authorized administrator of Chapman University Digital Commons. For more information, please contact [email protected]. School Psychologists’ Training and Knowledge of Tourette Syndrome A Dissertation by Leticia H. Cornejo Chapman University Orange, CA College of Educational Studies Submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy in Education: School Psychology August 2015 Committee in charge: Randy T. Busse, Ph.D., Committee Chair John Brady, Ph.D. Dawn Hunter, Ph.D. School Psychologists’ Training and Knowledge of Tourette Syndrome Copyright © 2015 by Leticia H. Cornejo iii ACKNOWLEDGEMENTS I have been very blessed to have met so many wonderful people at Chapman University. I am grateful to have been taught by Dr. Brady, Dr. Busse, Dr. Cardinal, Dr. Colbert, Dr. Hass, and Dr. Hunter, who love what they do and genuinely care for their students. I would like to thank Dr. Brady for agreeing to be a part of my dissertation committee.
    [Show full text]
  • Charcot's Contribution to the Study of Tourette's
    Arq Neuropsiquiatr 2008;66(4):918-921 Historical note CHARCOT’S CONTRIBUTION TO THE STUDY OF TOURETTE’S SYNDROME Hélio A.G. Teive1, Hsin Fen Chien2, Renato Puppi Munhoz1, Egberto Reis Barbosa2 Abstract – We review the history of Tourette syndrome, emphasizing the contribution of Jean-Martin Charcot. Key Words: Tourette syndrome, Gilles de la Tourette, Jean-Martin Charcot, tics, coprolalia. A Contribuição de Charcot para o estudo da síndrome de Tourette Resumo – revisamos a história da síndrome de Tourette, com ênfase a contribuição de Jean-Martin Charcot. PAlAvrAs-ChAve: síndrome de Tourette, Gilles de la Tourette, Jean-Martin Charcot, tiques, coprolalia. Tourette’s syndrome (Ts) is a chronic neuropsychiatric have been presented to the public in the book “Malleus disorder characterized by multiple motor tics associated maleficarum”, or “Witch’s hammer”, by Jakobs prenger and with the presence of one or more phonic tics, with wax- heinrich Kraemer, published in 1489. The book includes ing and waning course and severity1,2. The estimated prev- a description of a priest who had motor and vocal tics, alence of the disease ranges from 1 to 10 per 1000 children which at that time was believed to be related to posses- and adolescents, being associated with various comorbid- sion by the devil, witchcraft and exorcism, as well as with ities such as attention deficit and obsessive-compulsive the inquisition10. disorders1,2. These comorbidities have been reported in other important contributions to the description of various series of Brazilian patients in the literature3-5. It is Ts include that by Armand Trousseau (1801–1867), a fa- believed nowadays that Ts has significant genetic determi- mous 19th century French physician.
    [Show full text]
  • Clinical and Organizational Applications of Applied Behavior Analysis Clinical and Organizational Applications of Applied Behavior Analysis
    CLINICAL AND ORGANIZATIONAL APPLICATIONS OF APPLIED BEHAVIOR ANALYSIS CLINICAL AND ORGANIZATIONAL APPLICATIONS OF APPLIED BEHAVIOR ANALYSIS Edited by HENRY S. ROANE Upstate Medical University, Syracuse, New York, USA JOEL L. RINGDAHL Rehabilitation Institute, Southern Illinois University, Carbondale, Illinois, USA TERRY S. FALCOMATA Department of Special Education, The University of Texas at Austin, Austin, Texas, USA AMSTERDAM • BOSTON • HEIDELBERG • LONDON NEW YORK • OXFORD • PARIS • SAN DIEGO SAN FRANCISCO • SINGAPORE • SYDNEY • TOKYO Academic Press is an imprint of Elsevier Academic Press is an imprint of Elsevier 125 London Wall, London, EC2Y 5AS, UK 525 B Street, Suite 1800, San Diego, CA 92101-4495, USA 225 Wyman Street, Waltham, MA 02451, USA The Boulevard, Langford Lane, Kidlington, Oxford OX5 1GB, UK First published 2015 Copyright © 2015 Elsevier Inc. All rights reserved. No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, recording, or any information storage and retrieval system, without permission in writing from the publisher. Details on how to seek permission, further information about the Publisher’s permissions policies and our arrangement with organizations such as the Copyright Clearance Center and the Copyright Licensing Agency, can be found at our website: www.elsevier.com/permissions This book and the individual contributions contained in it are protected under copyright by the Publisher (other than as may be noted herein). Notices Knowledge and best practice in this field are constantly changing. As new research and experience broaden our understanding, changes in research methods, professional practices, or medical treatment may become necessary. Practitioners and researchers must always rely on their own experience and knowledge in evaluating and using any information, methods, compounds, or experiments described herein.
    [Show full text]