Quiz Questions on Anemia

WJOA

Anemia, the commonest blood disorder still poorly Q7. Which of the following is not an etiology of Fe understood, is prevalent from newborn, to adolescents, deficiency anemia? in pregnancy, and till menopause! A small quiz may give a. Chronic blood loss some answers. b. Increased requirement Q1. Which of the following is NOT a cause of microcytic c. Infection anemia? d. Malabsorption a. Thalassemia e. Decreased intake b. Anemia of chronic disease Q8. TIBC increases in iron deficiency anemia because c. Iron deficiency anemia a. Inflammatory response to deficiency d. Pancytopenia b. Compensation by other factors e. Lead poisoning c. Ability to absorb increases Q2. The lab reports for a patient with low mean cell Q9. Pica, a clinical presentation for Fe deficiency volume show high serum ferritin and low total iron anemia, is binding capacity. What is the most likely cause for a. Itchiness this patient’s anemia? b. ED a. Fe deficiency c. Desire to eat weird things b. Anemia secondary to inflammation d. A small woodland creature c. Thalassemia d. Hemoglobinopathy Q10. Which lab investigations would you order if you suspect Fe deficiency anemia? (check all that apply) Q3. Fe is absorbed in the a. CBC a. Stomach b. Blood smear b. Duodenum c. Serum iron c. Jejunum d. Serum ferritin d. Ileum e. TIBC f. All of the above Q4. Where is most nonheme iron found in the body? a. Bound to IF Q11. Where is beta-thalassemia most common? (check b. Bound to transferrin all that apply) c. Free in plasma a. West Africa d. Stored in liver b. Mediterranean c. Arabian Peninsula Q5. Select the following that enhance Fe absorption d. South East Asia (select all that apply) e. Canada a. Citric acid Q12. What is the difference between beta-thalassemia b. Polyphenols (tea) major and beta-thalassemia minor? c. Phytate (bran) a. Homozygous vs heterozygous d. Calcium b. Acute vs chronic e. Ascorbic acid c. Legal drinking age

Q6. What is the most important test for Fe stores? Q13. Heinz bodies are made of: a. Serum iron a. Excess gamma chains b. TIBC b. Excess alpha chains c. Serum ferritin c. Excess beta chains d. Excess ketchup

69 Maninder Ahuja

Q14. Beta-thalassemia, unlike alpha-thalassemia, pres- Q19. Aplastic anemia can be acquired (more common) ents at approximately 6 months of age. and inherited. What are some of the ways it can be a. True acquired? b. False a. Postviral infection b. Pregnancy Q15. Which would you expect to see on a blood smear c. Ionizing radiation for beta-thalassemia? (select all that apply) d. Drugs and chemicals a. Heinz bodies e. Idiopathic b. Multinucleated neutrophils f. All of above c. Target cells d. Hypochromic microcytic cells Q20. Aside from the gradual onset signs of anemia, what e. Hyperchromic microcytic cells other clinical presentations would you see with aplastic anemia? Q16. What is the treatment for beta-thalassemia minor? a. Koilonychias, “spoon nails” a. Blood transfusions b. Associated thrombocytopenia, e.g., history of b. Iron chelation bleeding from the gums c. Bone marrow transplant c. Neutropenia, e.g., repeated bacterial infections d. None of the above d. Purpura e. Pica Q17. Decreased or stopped production of alpha-globin chains results in HbH (4 gamma chains together) Q21. How would you diagnose aplastic anemia? and Hb Barts (4 beta chains together) a. Blood smear a. True b. Bone marrow biopsy b. False c. Spleen biopsy d. CBC Q18. On a CBC for alpha-thalassemia, you would see e. Liver biopsy anemia and reticulocytosis. On the blood smear, you would see Heinz bodies, hypochromic micro- Q22. Select treatment options for aplastic anemia cytic cells, and occasional target cells. Select the a. IV equine ATG others that you would see increase: b. Bone marrow transplant a. LDH c. Splenectomy b. Unconjugated bilirubin d. Immune suppression c. Conjugated bilirubin d. Urine urobilinogen e. Urine hemosiderin

Maninder Ahuja Vice President FOGSI

(2013–2014)

21(b), 22(a, b, d) b, 22(a, 21(b),

12(a), 13(b), 14(a), 15(a, c, d), 16(d), 17(b), 18(a, b, d, e), 19(f), 20(b, c, d), d), c, 20(b, 19(f), e), d, b, 18(a, 17(b), 16(d), d), c, 15(a, 14(a), 13(b), 12(a),

1(d), 2(b), 3(b), 4(b), 5(a, e), 6(c), 7(c), 8(c), 9(c), 10(f), 11(b, c, d), d), c, 11(b, 10(f), 9(c), 8(c), 7(c), 6(c), e), 5(a, 4(b), 3(b), 2(b), 1(d), Answers: