The NIDA CTN New England Consortium CTN New Englander newsletter

Winter 2014 Volume 4, Issue 1

Winter 2014

Study Updates CTN-0047 Screening, Motivational Assessment, Referral, and Treatment in Emergency Departments (SMART-ED). Study results were shared with the participating sites on Octo- ber 30, 2013.

CTN-0049 Project HOPE. Study recruitment & enrollment complete! This study is being conducted locally at Boston University-Boston Medical Center. Research staff affiliated with the Boston Medical Center’s Center for Infectious Diseases are conducting the study. Boston Medical Center started recruiting and enrolling study partici- IN THIS ISSUE pants in August 2012. The BU Medical Center site randomized the 800th par- ticipant in the study on January 30, 2014. As of February 2, 2014, 801 were Node News 1 randomized into the study overall with 94 randomized/enrolled at the BU Medi- Protocol Updates cal Center site. Treatment exposure remains high at 84% and the site is at 100% for the availability of primary outcome data trial performance metric. News from Field 2

CTN-0050 START Follow-Up Study. Lead Investigator, Yih-Ing Hser is conducting a long Research News term follow-up of participants from the original START protocol (CTN 0027). Two sites from Publications, 3 the former New England Node, Connecticut Counseling Centers and Hartford Dispensary Presentations and participated in CTN0027. The Hartford Dispensary and the research team from the Yale Upcoming Meetings RRTC are participating in CTN 0050. As of Sunday January 12, 2014, 130 participants have been enrolled from Harford Dispensary and 95 participants have been recruited from the Connecticut Counseling Center and have achieved high rates for the availability of primary outcome data: 100% (Hartford Dispensary) and 99% (CT Counseling Ctr.). The Connecticut sites are finished with data collection and data cleaning.

Upcoming CTN Studies in the New England Consortium CTN-0051 X: BOT Study. This study being led by John Rotrosen, M.D. from the Greater New York Node and the New York University School of Medicine will take place locally at Stanley Street Treatment & Resources, Inc. (SSTAR) in Fall River, Massachusetts.

CTN-0053 ACCENT Study. This study being led by Kevin Gray, M.D., from the Southern Consortium Node and the Medical University of South Carolina will take place locally at The APT Foundation in Connecticut. The pre-initiation site visit by the CTN Clinical Coordinating Center is scheduled for January 31, 2014.

The New Englander

2013 Nyswander/Dole “Marie” Award John Hamilton, LMFT, CEO of Recovery Network of Programs, Inc. (Connecticut) was one of 8 recipients of the 2013 Nyswander/Dole “Marie” Award. Awardees are nominated and selected by their peers for outstanding service and ongoing commitment to making advances in opioid treatment in the community. The awards were presented at the 2013 American Association for the Treatment of Opioid Dependence, Inc. (AATOD) Conference in Phila- delphia on November 12, 2013. Dr. Vincent Dole and Dr. Marie Nyswander were the first recipients of this Award in 1983. The Association has been responsible for bestowing this honor since the first Regional Conference of 1984 in New York.

2014 Visionary Leadership Award from the National Council for Behavioral Health

Nancy Paull, CEO of SSTAR was recently selected as an honoree for a 2014 Visionary Leadership Award from the National Council for Behavioral Health. The award recognizes the impact of organizations and leaders in the behav- ioral health field, committed to providing community-based treatment for indi- viduals with mental illnesses and substance use disorders.

CTN Research Abraham AJ, Knudsen HK, Roman PM. The relationship between Clinical Trial Network protocol involve- ment and quality of substance use disorder treatment. J Subst Abuse Treat. 2014 Feb;46(2):232-7. doi: 10.1016/j.jsat.2013.08.021. Epub 2013 Sep 27.

Abstract

The National Institute on Drug Abuse's Clinical Trials NetworkNetwork (CTN) is a practice-based research network that partners academic researchers with community based substance use disorddisorderer (SUD) treatment pro- grams designed primarily to conduct effectiveness trials of promising interventions. A secondary goal of the CTN is to widely disseminate results of these trials and thus improve the qualityquality of SUD treatment in the US. Drawing on data from 156 CTN programs, this study examines the association between involve- ment in CTN protocols and overall treatment quality measurmeasureded by a comprehensive indexindex of 35 treatment services. Negative binomial regression models show that treatment programs participatiparticipatinngg in a greater number of CTN protocols had significantly higher levels of treatment quality, an assoassociationciation that held after controlling for key organizational characteristics. These findings contribute to the growing body of research on the role of practice-based research networks in promoting health care quality.

Samuel Ball, PhD to lead the National Center on Addiction & Substance Abuse (CASA) Dr. Ball from School of Medicine and the APT Foundation was recently named the presi- dent and chief executive officer of the National Center on Addiction and Substance Abuse (CASA). CASA was established in 1992 at Columbia University. Congratulations, Dr. Ball!

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The New Englander

PRESENTATIONS:  SF Greenfield. presented at the Advisory Council on Services for Women (ACSW) for the Substance Abuse and Mental Health Services Administration (SAMHSA) on "Gender Specific Treatment for Women with Substance Use Disorders: The Women's Recovery Group Study" in August, 2013.

 Connery, H. Presented findings from CTN-0010 & CTN-0030 to the McLean Hospital National Council, October 23 & 24, 2013.

 Griffin M, Dodd D, Rice, L, Weiss R. Characteristics and Treatment Outcomes in Prescription Opioid- Dependent Patients with and without Co-Occurring Psychiatric Disorder. III International Congress Dual Disorders, October 25, 2013, Barcelona, Spain.

 Weiss, RD. Treatment of Prescription Opioid Dependence. Boston University School of Medicine. De- cember 12, 2013.

PUBLICATIONS:  Griffin ML, Dodd DR, Potter JS, Rice LS, Dickinson W, Sparenborg S, Weiss RD. Baseline characteristics and treatment outcomes in prescription opioid dependent patients with and without co-occurring psychiatric disorder. Am J Drug Alcohol Abuse, 2013 Nov 12. [Epub ahead of print].  Hser YI, Saxon AJ, Huang D, Hasson A, Thomas C, Hillhouse M, Jacobs P, Teruya C, McLaughlin P, Wiest K, Cohen A, Ling W. Treatment retention among patients randomized to buprenorphine/naloxone compared to in a multi-site trial. Addiction. 2013 Aug 20. doi: 10.1111/add.12333. [Epub ahead of print]  Meade CS, Bevilacqua LA, Moore ED, Griffin ML, Gardin JG 2nd, Potter JS, Hatch-Maillette M, Weiss RD. Concurrent substance abuse is associated with sexual risk behavior among adults seeking treatment for prescription opioid dependence. Am J Addict. 2014 Jan-Feb;23(1):27-33. doi: 10.1111/j.1521- 0391.2013.12057.x. Epub 2013 Jul 29. PMID: 24313238 [PubMed - in process]  Schuman-Olivier Z, Connery H, Griffin ML, Wyatt SA, Wartenberg AA, Borodovsky J, Renner JA Jr, Weiss RD. Clinician beliefs and attitudes about buprenorphine/naloxone diversion. Am J Addict. 2013 Nov-Dec;22(6):574- 80. doi: 10.1111/j.1521-0391.2013.12024.x. Epub 2013 Apr 11

UPCOMING MEETINGS/CONFERENCES:  McLean Hospital/Harvard Medical School—Addictions in 2014. Royal Sonesta Hotel. Cambridge, MA. May 16-17, 2014. http://www.hms-cme.net/3424353/#faculty  Massachusetts NASW Symposium. Sheraton Framingham Hotel and Executive Conference Center. April 3-4, 2014.

Substance Use Issues and Treatment in the Media

An article in the Boston Sunday Globe (January 19, 2014), “On the long trail back to hope” profiles the scourge of in Vermont.

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