OSR1 (phospho Thr185) Antibody Cat. No.: 79-859

OSR1 (phospho Thr185) Antibody

Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using OSR1 (Phospho-Thr185) antibody (left) or the same antibody preincubated with blocking peptide (right).

Specifications

HOST SPECIES: Rabbit

SPECIES REACTIVITY: Human, Mouse

OSR1 (phospho Thr185) antibody was raised against a peptide sequence around IMMUNOGEN: phosphorylation site of threonine185 (R-K-T (p)-F-V) derived from Human OSR1.

TESTED APPLICATIONS: IHC, WB

APPLICATIONS: Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

The antibody detects endogenous levels of OSR1 only when phosphorylated at threonine SPECIFICITY: 185.

PREDICTED MOLECULAR 65 kDa WEIGHT:

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PURIFICATION: Antibodies were purified by affinity-chromatography using epitope-specific peptide.

CLONALITY: Polyclonal

ISOTYPE: IgG

CONJUGATE: Unconjugated

PHYSICAL STATE: Liquid

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM BUFFER: NaCl, 0.02% sodium azide and 50% glycerol.

CONCENTRATION: 1 mg/mL

STORAGE CONDITIONS: Store antibody at -20˚C for up to one year.

Additional Info

OFFICIAL SYMBOL: OXSR1

ALTERNATE NAMES: OXSR1, kinase OSR1, Oxidative-stress responsive 1

ACCESSION NO.: NP_005100.1

PROTEIN GI NO.: 4826878

GENE ID: 9943

Background and References

Oxidative-stress responsive 1 is located in the vicinity of three others - GOLGA4, ITGA9 and HYA22 on 3. These four genes are considered to be BACKGROUND: candidate tumor suppressors. Oxidative-stress responsive 1 has similarity to human Ste20/oxidant stress response kinase-1 and is thought to be involved in the response to oxidative stress

REFERENCES: 1) Tamari M., J. Hum. Genet. 44:116-120(1999).

2) Kikuno R., DNA Res. 6-197-205(1999).

3) The MGC Project Team; Genome Res. 14:2121-2127(2004).

ANTIBODIES FOR RESEARCH USE ONLY.

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