® Scientifi c, Inc. Instruments for Science from Scientists J-KEM

Temperature Control

Reaction Automation

Custom Robotics

J-KEM Scientifi c 2009 Product Highlights Digital Temperature Controllers Precision Temperature Controllers for Research in • Regulate volumes from 100 µL to 22 L 2009 High Power & High Safety Controllers NEW • Reactors up to 100 L • USB standard on all 200-Series temperature Economy Temperature Controllers and vacuum controllers

• Free Windows control & Digital Vacuum Regulator data logging software

• Digital Control of Vacuum Pressure from 760 to 0.1 torr • 0.1o C Regulation • Regulate Vacuum to 0.1 torr with DVR-1000 < 1o C Over-shoot

Parallel Synthesis & Lab Automation Equipment Syringe Pumps Parallel Reaction Systems • Delivery rates from 1 µL/min • Solution phase & solid to 375 mL/min phase reaction systems

• Single & Multi- • PC control of: position pumps - Reagent delivery - Temperature • PC & stand - Pressure alone operation • Custom designs • Deliver any volume from any syringe Reaction Block Systems

• KEM-Lab Personal Reaction Blocks • Heat, cool, & refl ux

• Multiple vial sizes

• Custom designs • Multiple Temperature Zones Custom Robotic Workstations Robotic Solutions • Custom hardware and software • Weighing • Dissolution • Reformatting • Solid & Solution phase Synthesis • Cherry picking • Solid phase extraction User Programmable • All robots include the original source code

- Endeavour Robots NEW Capping/Uncapping priced from $6000 Station Index Adapters, Thermocouple 39 Personal Reaction Station 16 Temperature Controllers Automation Equipment Pressure Regulator, Digital 31 Research Controllers 32-37 Robotics 2-9 Reaction Blocks Multi-Channel 34 Fluid Delivery 10-15 Single Temperature Zone 18 Safety 35 Reactors 14-15, 25 Multi-Temperature Zone 22 High Power 35 Chiller, Circulating 24 Custom 20-21 Oil Bath Controller 36 Evaporators Shaker 19 Economy 36 KEM-Vap 27 Reaction Controller 14 Custom 25 Microtiter Plate 23, 27 Robotics Monitors 28 Reaction Block 18 Instruments 2-7 Safety Limit Controller 28 Custom 27 Accessories 8-9 Power Controller 29 Fraction Collector 9 Do-It-Yourself 7 Thermocouples & Accessories 38-39 Gas Heater 29 Safety Equipment Temperature Monitor 28 Glass Microtiter Plate 23 Lab Safety Controller 28 Thermocouples Heating Mantles 40 Water Flow Monitor 28 Single Element 38-39 Hand-Held Meters 29 Digital Temperature Monitor 28 Dual Element 35 KEM-Lab Reactors 23 Temperature Controllers 35 Glass Coated 38 KEM-Prep Reactor 17 Shakers Tefl on Coated 38-39 KEM-Vap Evaporator 27 Benchtop, Reaction Block 19 Hypodermic Needle Probe 39 Monitors KEM-Lab 23 Thin Wire 39 Temperature 28 Robotic 8 Cords and Accessories 38 Vacuum 30 Solid Phase Extraction Station 8 Trinity Power Controller 29 Water Flow 28 Solid Phase Synthesis Reactor 26 USB Network Extenders 37 Nitrogen Gas Heater 29 Solvent Evaporator 27 Vacuum Regulator, Digital 30 Oil baths, Instatherm 40 Stirrer, Miniature Overhead 25 Monitors 30 Over-Head Stirrer 25 Syringe Pump Precision 31 Parallel Synthesis Reactors Single and Multi-Channel 10-13 Variac, Solid State 29 Solution Phase 15-23 Custom 11-14 Water Flow Monitor 28 Solid Phase 26 Do-It-Yourself 11 Who We Are 41 Heating Profi le of J-KEM’s Temperature Control 200-Series Temperature Controllers

J-KEM’s patented power control computer makes this the only controller that can heat volumes under 100 µL with the safety of 0.1o C regulation. Actual heating data is shown at right. Model 210 controller shown with power control computer

Ordering Information The J-KEM® Guarantee All J-KEM products are guaranteed to be the highest quality and most accurate instruments available. Any J-KEM product ® not meeting your expectations can be J-KEM Scientifi c, Inc. returned within 30 days for a full refund. Phone: (314) 863-5536 Robert C. Elliott / President J-KEM Scientifi c, Inc. (800) 827-4849 6970 Olive Blvd. FAX: (314) 863-6070 Saint Louis, MO 63130 Email: [email protected] USA On-line Catalog: http://www.jkem.com Custom Laboratory Robotics

Eclipse With four robot styles and multiple software options, J-KEM is Workstation uniquely positioned to offer custom robotic solutions for virtually any lab automation need. J-KEM’s technology makes lab automation as Simple as 1, 2, 3.

1 Four Robotic Platforms to Choose From Key Features: • Fast • Positional accuracy • Affordable • Multiple Z-probes With four different robotic platforms, J-KEM can select the one that most effi ciently automates your unique application. Each platform has its own set of advantages including speed, positional accuracy, power, Phoenix Workstation and price that make it the preferred system for different applications.

Key Features: • Large deck size • Multiple Z-probes 2 Custom Solutions • Generates > 100 lb. of force in the Z- direction. J-KEM offers complete hardware and software solutions for almost any Voyager lab automation task. Every workstation is customized with the features Workstation and software needed to run your specifi c application. Workstations for: • Weighing • Dissolution • Synthesis • Sorting • Crystallization • Cherry picking • SPE • SPS • Spectroscopy

Key Features: • Fast • Optimized for microvial weighing and cherry picking applications 3 Do-It-Yourself Robotics Endeavour Workstation New in 2009 J-KEM offers each of its robotic systems with custom programming, professional installation, and user training. For most researchers, this is the service they both need and expect. For those research teams who prefer to do it themselves, J-KEM now offers each of its robotic systems as a fully confi gured and tested workstation, but with no pre-installed software. With complete systems starting under $6,000, this is a highly affordable way to introduce robotics to your workfl ow. Software options are available to support your custom development. Key Features: • Fast • Positional accuracy • Most affordable workstation available

Page 2 J-KEM Scientifi c Toll-free: (800) 827-4849 Fax: (314) 863-6070 www.jkem.com [email protected] Eclipse Robotic Workstations

The Eclipse workstation uses modular X- and Y-axis rails combined with a Value: From $20,000 wide selection of automated tools such as grippers, multi-position needles, and custom probes. The open design of the Eclipse provides easy access to the entire workstation deck.

Affordability: The affordable price of the Eclipse (starting under $20,000) creates new opportunities for lab automation. For example, a weighing station with bar code scanner and 0.01 mg resolution balance costs about $28,000.

Features: • Speed: 400 mm/sec • Positional Accuracy: ±0.02mm • Z-Axis Force: 10 pounds Examples of Eclipse Workstations

Test Tube • Bar code scanner • Analytical balance Plate Washer with Weighing Station • Excel output Heated Reaction Station

See the Eclipse in action at: www.jkem.com/robotics

• Multi-step synthesis program run in micro titer plate cells • Plate gripper Solid Phase • Temperature controlled reactor Extraction Station • 24 Columns developed in parallel • Controls fl ow rate in all columns • Solvent level in each column is optically monitored to stop solvent fl ow when the solvent front reaches the top of the packing.

Derivatization Station

Spectroscopy Robot

• Automated spectroscopic • Reagent addition to septum vials analysis of 200 samples • Heated reactor with mixing • Reaction mixture sampled at user set times to GC vials

J-KEM Scientifi c Toll-free: (800) 827-4849 Fax: (314) 863-6070 www.jkem.com [email protected] Page 3 Advantages of J-KEM Robotics

Custom Design While others start from an existing design, then try to make your application fi t their instrument, every J-KEM workstation is designed from scratch to implement your automation task effi ciently and with an eye towards future expandability. J-KEM’s experience in lab automation, including temperature control, reactor design, fl uid delivery, solid and solution phase synthesis is invaluable when optimizing the design of custom robotics.

Polymer Compounding Robot Modules: 4-Temperaure zone reaction block, balance, bar code reader, heated & cooled reagent block, cooled 4-position sonicator, precision syringe pump with 16 reagent ports, 6-zone temperature controller, and needle wash station. Custom Software You Own the Solution Custom software is written for every workstation to provide an J-KEM believes that you should not only own the instrument, but you intuitive user interface. The procedure’s setup, the way data is read should own the technology that created the instrument. That’s why into and out of the program, and the exact sequence of program steps we are the only company that releases the original source code with are all customized to make the operation of your robot both effi cient every robot. This gives you the power to change every aspect of the and user friendly. robot’s operation as your automation needs change.

Personal Service J-KEM is committed to personal service, offering any support that’s needed to assure the successful integration and productivity of our automation solutions. With one phone call, you can talk to the engineer who designed your robot, the engineer who installed it, and the software engineer who wrote the program. Value J-KEM’s custom robotics are often half the price of other companies’ “one-size-fi ts-all” alternative. While many of the modules on a workstation are standard J-KEM products, we also use the best available instruments like balances, bar code readers, and pumps to assemble the fi nal workstation in the most affordable and effi cient Why is it important to own the original source code? manner. Without the source code, you’re stuck with the robot you have It’s not really enough to own the code if it’s not easy to use. rather than the robot you need as your automation needs change. For example, suppose the robot’s original task was weighing and Written in VB.Net, the robotic For Vial = 1 to 96 dissolving samples to specifi c concentrations, but now you need it to software contains intuitive, Rack.MoveToCell(XY, Vial) add reagents to 4 mL septum vials in a temperature controlled reactor high level functions that make Gripper.PickUpVial() with mixing. In most cases you’d need to purchase a new robot. understanding or modifying Balance.Tare() Even for small changes, if you don’t own the original source code, your code easy. Consider the Balance.MoveToCell(XY, 1) then you’re 100% dependent on the company who does. J-KEM MyWeight = Balance.Weight() example to the right that weighs offers ongoing software support for all of our customers. But still, PutVialBack(Vial) every vial in a 96 vial rack. to own the tools that place you in control of your own workstation is Next invaluable.

Page 4 J-KEM Scientifi c Toll-free: (800) 827-4849 Fax: (314) 863-6070 www.jkem.com [email protected] Phoenix Robotic Workstations Phoenix workstations have three distinctive characteristics: 1. Large deck size that allows access to multiple racks and modules such as shakers, balances, and fi lter stations.

2. Multiple Z-probe tools. This robot has simultaneous access to three 2.5 mL disposable tip probes, three 200 µL disposable tip probes, a septum penetrating needle, a vial gripper, three stainless steel cannula, and a pressure plate to fi lter samples using positive pressure.

3. The Z-axis can develop over 100 pounds or force, enough to penetrate any septum or seal any reactor. Sample Dilution and Filtration Station

Examples of Phoenix Workstations Cherry Picking and Sample Reformatting Workstation Robot Modules Workstation Procedure • Deck fi ts fi ve Gilson racks In this application, samples arrive in a variety of formats, of any style including 4 mL, 8 mL, and 20 mL vials, three different • Disposable pipette tip probe size test tubes, 24, 48, and 96 well titer plates. This • Syringe pump with 8-port workstation reformats samples from the various tubes to selectable valve a single 96 well plate. From the master plate, a cherry picked plate is made based on the input from an Excel table.

Enzyme Specifi c Activity Workstation

Workstation Procedure Robot Modules Samples are transferred, • Analytical balance by weight, to 400 mL • 60-position high power magnetic stirrer beakers where they are • Syringe pump with 8-port selectable valve diluted 1200-fold. After mixing, diluted samples • Gripper for vial transport are dispensed to sample • Cannula for large volume dispenses (> 100 mL) vials for analysis. and analytical needle for microliter dispenses

Sample Dissolution and Daughter Plate Preparation Robot Modules • Syringe pump with 8-port Workstation Procedure selectable valve Dissolves solid samples to a standard concentration, • Analytical balance then adds additional liquid reagents. After mixing, transfers aliquots to HPLC vials with septum caps • Bar code station and to a titer plate cell. The identity of all vials • Gripper for vial transport are tracked by bar code, and the volume of reagents • Septum penetrating needle dispensed is verifi ed by weight.

J-KEM Scientifi c Toll-free: (800) 827-4849 Fax: (314) 863-6070 www.jkem.com [email protected] Page 5 Voyager Robotic Workstations

The Voyager workstation is optimized for weighing and sorting glass or plastic vials in 96 position tube racks. The Voyager integrates a Mettler balance with 10 µg resolution, an Opticon 2D bar code scanner, and high speed X, Y, & Z drives. Combining world-class hardware with intuitive software makes the Voyager the fi nest workstation for tube handling available.

See the Voyager in action at: www.jkem.com/robotics

Features: • Weighs up to 220 vials per hour • 0.00001 g (10 µg) balance • 2D bar code scanner decodes 2D and all 1D bar code symbologies • Gripper customized to individual vials Intuitive Software • Reads and writes to any data base Voyager’s software includes applications for weighing, scanning, sorting, and cherry picking • Liquid dispensing/transfer options tubes. Support for data input and output from a variety of fi le formats, including Excel, .CVS, and .TXT fi les is standard. Custom input/output fi le formats to access corporate data bases Applications: or to interface with other laboratory instruments is available. The Z-arm automatically adjusts to different tube heights and even supports different tube sizes in the same run. Various liquid • Tube identifi cation and weighing dispensing options are available for microliter to milliliter aspirate and dispense operations. • Tube sorting and re-arraying • Cherry picking

Voyager-12 Workstation The Voyager-12 has positions for 12 tube racks and 2 additional receiving racks for re-arraying or cherry picking. Includes a Mettler balance with 10 µg resolution and 2D bar code scanner. Specifi cations: Dimensions: 30” x 26” x 20” (DxWxH) Speed, X & Y-axis: 120mm/sec $19,950 Positional accuracy: 0.02mm Tube Heights: 0.5 to 2.5 inches Communications: Requires 1 USB port Power: 120 watts Voyager-24 Workstation The Voyager-24 has positions for 24 tube racks plus 2 additional receiving racks for re-arraying or cherry picking. Includes a Mettler balance with 10 µg resolution and 2D bar code scanner. Microtube above Specifi cations: balance pod Dimensions: 30” x 38” x 20” (DxWxH) Speed, X & Y-axis: 120mm/sec Positional accuracy: 0.02mm $21,600 Tube Heights: 0.5 to 2.5 inches Communications: Requires 1 USB port Power: 120 watts Optional Features The Voyager workstation • Stainless steel or Tefl on cannula for the addition of can be equipped with custom liquid reagents grippers to • Spectroscopic probes transport a variety of • Mixing tube styles, • Heated reaction stations including • Custom user modules centrifuge tubes.

Page 6 J-KEM Scientifi c Toll-free: (800) 827-4849 Fax: (314) 863-6070 www.jkem.com [email protected] Endeavour Robotic Workstations

The Endeavour is J-KEM’s most compact and affordable Starting system, an ideal choice when either bench space or budgets are limited. The Endeavour under $6000 is also a great starting point for researchers who want to develop their own automation instruments. In one compact enclosure, the Endeavour includes all the needed electronics, drivers, and power supplies. Combined with J-KEM’s software, the Endeavour can be programmed to run complex motion control programs, even 3-axis arc interpolations, in a matter of hours. The Endeavour is servo motor controlled to provide rapid and precise motions with positional accuracies of 0.02mm.

Software Support Two software packages are available for the Endeavour robot. Endeavour.dll exposes high level functions, like those shown in the example below, that handle all of the low-level tasks associated with serial communications and motor control. Endeavour.dll exposes functions for every motion parameter including acceleration, positioning, homing an axis, and I/O support. Endeavour.dll is included at no charge with all orders. J-KEM also offers its AutoKem software written in Microsoft’s Visual Studio 2008.Net in the Visual Basic language. AutoKem provides the user with a feature rich application having classes for racks, balances, syringe pumps, bar code readers, and many other instruments so they can be added to an application with only a few lines of code. The original source code for AutoKem is provided to further support Examples of Robot Commands from Endeavour.dll custom programming. Command Description HOME(X) Home the X axis. MOVE(Y,127.40) Move on the Y axis to position 127.40 mm. J-KEM MOVE(X,100.0, Y,235.0, Z,25.5) Perform a simultaneous 3-axis manufactures move to the specifi ed coordinates. custom OUTPUT(12,ON) Turn user I/O output 12 on. modules INPUT(7) Returns 0 if the input is low, 1 if high. for the Z Two Axis Endeavour plate of the Endeavour Endeavour-22020 Catalog # Price robot. Two Axis Endeavour Robot Provides 200mm of addressable space on both the EN22020 $5,995.00 X- and Y-axes. Y-axis supports 9 pounds. Dim: 320 x 405 x 320 mm (W x D x H). Two Axis Endeavour Robot Provides 400mm of addressable space on both the EN24040 7,995.00 · Grippers X- and Y-axes. Y-axis supports 9 pounds. Dim: 520 x 605 x 320 mm (W x D x H). · Needles Three Axis Endeavour Robot Provides 200mm of addressable space on both the EN32020 7,640.00 · Syringes X- and Y-axes and 100mm of stroke length in the Z-dimension. Z axis supports up to 4.5 pound loads. Dimensions: 330 x 405 x 420 mm (W x D x H). · Disposable tips Three Axis Endeavour Robot Provides 400mm of addressable space on both the EN34040 9,340.00 X- and Y-axes and 100mm of stroke length in the Z-dimension. Z axis supports up to 4.5 pound loads. Dimensions: 530 x 605 x 420 mm (W x D x H). Endeavour Software Catalog # Price Endeavour.dll Software support for the Endeavour robot. N. C. AutoKem Software Source code in VB.Net 2008 for the Endeavour robot. AutoKem $795.00 Call J-KEM for complete function list. Specifi cations for all Endeavor Robots Call for drill guides and additional specifi cations. Speed: 1-300 mm/sec Positional Accuracy: 0.02 mm I/O: 16 general purpose optically isolated logic level inputs and 16 open collector optically isolated outputs (100 mA). +24 V & Gnd. Communications: USB and RS232 Power: 110 - 240 Vac input; 200 watts

J-KEM Scientifi c Toll-free: (800) 827-4849 Fax: (314) 863-6070 www.jkem.com [email protected] Page 7 Robotic Workstation Accessories Robotic Shaker Specially designed for robotic applications, this low profi le shaker is less than 5” tall. The key feature of the RS2000 is its ability to home to an absolute X- and Y-coordinate when stopped with accuracies better than 0.1mm in both the X and Y dimensions. Homing to a known coordinate allows the robot to reliably access modules attached to the shaker’s mounting plate. Triple eccentric drives provide vigorous mixing of loads up to 60 pounds.

Specifi cations: Dimensions: 12.25” x 20” x 4.75” (WxDxH) Rotational speeds: 40 - 525 rpm Maximum load: 60 pounds Shaking motion: Orbital or linear Catalog # Price Orbital radius: 0.4” Can be customized RS2000 $5,840.00 Communications: USB, RS232, RS485, binary, manual

Solid Phase Extraction Station The KEE-100 automates 24-positions of solid phase extraction. The KEE-100 works by Optical regulating the solvent fl ow rate and optically sensors monitoring the position of the solvent front Tefl on above the top of the column packing in each valve column individually. When the solvent front reaches the top of the packing, a Tefl on valve 24-microcontrollers closes preventing the packing from going Inside the dry. Individual control of solvent fl ow rate KEE-100 Specifi cations: and position ensure reproducible results. SPE 24 Positions columns can be developed either by vacuum or Column diameter: 1/8 to 1” positive pressure. Solvent compatibility: Organic & aqueous Flow rates: 0.05 to 4mL/min Includes: SPE station and computer controller KEE-100 Price: $25,200 Multi-Position Syringe Pumps

Custom syringe pumps with 4 to 48 glass and Tefl on syringes. Syringe pump controller (included) regulates the rate and volume of dispense and fi ll cycles and automatically refi lls syringes when needed. Dispenses from one or all syringes in parallel. Syringe sizes from 10 µL to 50 mL.

8-Position pump: From $8,240 Prices 16-Position pump: From 10,480 See page 10 for additional varies depending on syringe size and features 32-Position pump: From 14,960 syringe pump options 48-Position pump: From 19,440 Custom Modules J-KEM’s engineers Custom Fluid Heated and Cooled Reactors for design whatever is Dispensing Options incubations and crystallizations needed to effi ciently automate your laboratory task

4-Position Sonicater

Florescence Probe on Z-arm Temp. Controlled Filter Station Page 8 J-KEM Scientifi c Toll-free: (800) 827-4849 Fax: (314) 863-6070 www.jkem.com [email protected] Capping & Uncapping Station

J-KEM’s capping module automates the removal and replacement of caps from sample vials. The capper removes, then replaces one cap at a time eliminating the possibility of cross contamination. The top and bottom grippers automatically adjust to caps with diameters from 8 mm to 26 mm (2 mL to 20 mL vials) with no tooling changes, and can be adjusted for cap diameters up to 35 mm and vial heights of 125 mm. Thread pitch, the number of turns needed to remove a cap, and recapping torque are all software programmable. Available with RS232 or USB.

Capping Station Features: Price $12,750 · Automatically adjusts for - Cap diameter - Vial height - Thread pitch Adjustable capping force The capping station mounted · to a J-KEM weighing robot · No limit on the number of turns Fraction Collectors

J-KEM manufactures custom fraction collectors for any research application, from a simple 2 axis to a sophisticated 3 axis instrument running a custom, user specifi ed, program. Features: · External inputs & outputs for tube advance · Collect to a single or multiple racks · Fractions taken as a function of: - Time - Input voltage - User specifi ed parameter Custom fraction collector · Custom inputs/outputs to interface with other instruments holds 12 microtiter plates

The Endeavour’s affordable price makes it a perfect “intelligent fraction collector.” The Endeavour can be programmed to collect fractions based on any input parameter and according to any pattern.

For example: 1) Place the fi rst 40% and the last 40% of any peak in one common test tube, but put the middle 20% in a GC vial for analysis.

2) Collect each peak to a single tube. After the fractionation process is done, go back and transfer 1mL of each collected peak to a GC vial for analysis.

This is great stuff, but what I really need is......

J-KEM welcomes the opportunity to work with you on any automation project. Put our experience in robotics, reactor design, fl uidics, and custom programming to work for you.

J-KEM Scientifi c Toll-free: (800) 827-4849 Fax: (314) 863-6070 www.jkem.com [email protected] Page 9 Programmable Syringe Pumps Model SYR-1200 Single Position Dual Position Syringe Pump Syringe Pump • Flow rates from 0.75 µL/min to 375 mL/min

• Syringe automatically refi lls to deliver any volume from any syringe

• PC control and data logging with KEM-Commander software

The SYR-1200 syringe pump automates the addition of reagents at user entered rates. A programmable Ordering information distribution valve allows the system to dispense to and withdraw from up to 8 reagent bottles or reactors in any for the SYR-1200 and sequence. In addition to the standard programs pre-loaded in the controller (see below), J-KEM offers custom accessories is on programming at no additional charge to automate virtually any fl uid delivery task. Additionally, KEM-Commander page 13. PC software allows the user to build sophisticated delivery programs with an intuitive drag-n-drop interface. Standard Syringe Pump Programs Standard programs are permanent and pre-loaded in the syringe pump controller Program controlled distribution valve Program 1. Timed Addition Sequentially adds up to 16 reagents fi lls and dispenses from up to 8 ports to a single or multiple reactors at user specifi ed rates. The syringe automatically primes and refi lls with the active reagent as needed. Glass and Tefl on syringe Example (pump fi tted with a 5 mL syringe): 1) Add 12mL of reagent A at a rate of 3 mL/min Delivery rates from 2) Add 2.5mL of reagent B at a rate of 0.025 mL/min 0.75 µL/min to 375mL/min 3) Delay 1 hour 4) Add 10mL of reagent C at a rate of 60 mL/min Up to 16 pumps can be combined into a single system Program 2. Program Loader Use KEM-Commander PC software (included) to construct a custom syringe pump program in a drag-n- drop visual environment. Program Loader then uploads that program to nonvolatile memory in the syringe pump controller. Once stored in the controller, the program can be run at any time with no PC needed. KEM-Commander Software Construct programs for parallel reactions, fi lling titer plates, washing, or any custom application.

Program 3. PC Control Places all functions of the syringe pump KEM-Commander is under PC control. Useful for robotic applications or when part of a standard with every larger automated reaction system. pump and allows the user to construct sophisticated syringe Program 4. Custom At no additional charge, the user can specify pump programs in a custom syringe pump program. This program is written by J-KEM an intuitive drag-n- and stored as one of the permanent programs. drop environment. Programs can then Program 5. Update Manager Allows new or updated programs, be run/saved/recalled from the PC or available from J-KEM (via E-mail or web site), to be uploaded into uploaded to the pump. permanent memory.

Program 6. Concurrent Addition (SYR-2200 only) Adds two Program 7. Serial Dilution (SYR-2200 only) Repeatedly reagents in parallel to a common reaction at two independent rates. dispenses two reagents in a user specifi ed ratio.

For a comparison of the features of the SYR-1200 and the SYR-1400, see page 12.

Page 10 J-KEM Scientifi c Toll-free: (800) 827-4849 Fax: (314) 863-6070 www.jkem.com [email protected] NEW Model SYR-1400 Syringe Pump The SYR-1400 is the most versatile syringe pump available. The SYR-1400 is operated from a PC running J-KEM’s KEM-Pump software. KEM-Pump implements all the programs of the SYR-1200 plus additional programs for serial and multi-reactor reagent additions. Unlike any other syringe pump, KEM-Pump is an open source code application that allows researchers with programming experience to create their own applications without limitations (see blue insert below). Demo software at: www.jkem.com\syringepumps

Ordering information for the SYR-1400 and accessories is on page 13.

The SYR-1400 system includes both the syringe pump and KEM-Pump software. KEM-Pump is open source, graphical software that includes both pre-written applications and the original source code, in VB.Net, to allow users to create their own custom applications. KEM-Pump is a bold advance in laboratory automation that provides the user unprecedented control over how the syringe pump operates. KEM-Pump handles the low level tasks, like serial communications, then exposes high level functions for virtually any syringe pump action, greatly simplifying the effort needed to write new applications. For example, the code block below fully implements dispensing any volume of reagent at a user specifi ed rate; syringe refi lls are handled automatically. The list of functions and a complete programmer’s manual is available at jkem.com.

Public Sub StartTimedAddition(ByVal Exp as RunData, Byval PumpAddress as Int32) ‘Start a timed addition experiment. Data is contained in the RunData structure

Me.mnuStart.Enabled = False Me.mnuAbort.Enabled = True Pump.TimedAddition(Exp, PumpAddress, False) ‘Start the experiment and return immediately Do Pump.DrawPump(CurrentVolume) ‘Draw a graphical representation of the pump Me.txbAddedVolume.Text = Format(CurrentVolume, “0.000”) While Pump.IsRunning Me.mnuStart.Enabled = True Me.mnuAbort.Enabled = False End Sub Pre-written applications include: Timed Addition - Adds a single reagent (any volume) to a single reactor at a user specifi ed rate Multi-Step Timed Addition - Adds up to 16 different reagents, independent volumes and rates to a single reactor Multi-Reactor Addition - Adds a single reagent to 1-7 different reactors at independent rates and volumes Program Builder - A drag-n-drop application, for non-programmers, to build sophisticated pump programs Custom Syringe Pump Applications Sixteen pump system provides continuous delivery of 8 reagents in any volume and at independent rates. Custom Windows software, operator and administrator levels of program control, and data storage.

Pump with 4 independent temperature controllers. Maintains the temperature and pH in 4 independent reactions. Custom software with data logging, program storage and recall. Four Position Temperature and pH Controller 16-Position with half-sized pumps

J-KEM Scientifi c Toll-free: (800) 827-4849 Fax: (314) 863-6070 www.jkem.com [email protected] Page 11 Comparing the Features of the SYR-1200 and the SYR-1400 Syringe Pump Systems J-KEM’s two syringe pump systems, the SYR-1200 (page 10) and the SYR-1400 (page 11) share many of the same features, but differ in several important ways that may make one system better suited for your application. The key differences between the SYR-1200 and the SYR-1400 are 1) the SYR-1200 has its own syringe pump controller allowing it to be used as a stand-alone instrument while the SYR-1400 requires a PC for operation, and 2) the SYR-1400 is substantially more versatile, taking advantage of the power of a PC.

The SYR-1200 Both the SYR-1200 and The SYR-1400 the SYR-1400 use the same pump module. This means that both systems provide identical performance in regards to fl ow rate range and accuracy. It also means that both system use the same syringes, distribution valves and other accessories.

Controller Controller The SYR-1200 is operated from its own The SYR-1400 is operated from your PC. computer controller which means that a PC Programs are stored and recalled, and the is not required for operation. The controller experiment’s progress is displayed on the PC. stores and recalls the various programs and has a keypad for user input and a screen to display Standard Programs the experiment’s progress. The SYR-1400 comes with KEM-Pump graphical control software that runs the syringe Standard Programs pump module. KEM-Pump implements all of The syringe pump controller has the most the standard programs of the SYR-1200 plus common and useful pump applications loaded several others. into permanent memory (see page 10). Syringe • Sizes: 10 µL to 50 mL Custom Programs • Glass & Tefl on wetted J-KEM offers to write one custom program Custom Programs parts J-KEM offers to write one custom program and and add it to your copy of KEM-Pump at no • Dispense resolution is additional charge. load it into permanent memory at no additional 1/48,000 of the syringe charge. size in use • Easily interchangeable Creating New Programs Creating New Programs With the SYR-1400, new programs are created The SYR-1200 comes with a free PC Valve by adding your code to J-KEM’s open source application called KEM-Commander. With • With 3 to 8 program syringe pump application, KEM-Pump, written KEM-Commander, sophisticated script- selectable ports in Microsoft’s VB.Net. For researchers with style programs can be built in a drag-n-drop • All wetted Tefl on parts programming experience, the versatility of the environment that can then be run from the PC. syringe pump system is limited only by your KEM-Commander programs can be thousands Optional I/O imagination. KEM-Pump contains high level of commands long. Examples of program • Use external inputs to functions that provide intuitive access to every script commands are shown below. start/stop fl ow, change syringe pump feature. Using these functions, fl ow rate, or port virtually any syringe pump program can be Port(1) Go to valve port 1 position. created in a matter of hours. For researchers Fill() Fill the syringe • Control external valves without programming experience, one of the Rate(12.0) Set rate to 12 mL/min or other devices under screens in KEM-Pump builds new syringe Dispense(100.0) Dispense 100 µl program control. pump programs by dragging commands to a DelayMS(500) Delay 500 ms script-style command list. KEM-Pump also Withdraw(2500.0) Withdraw 2.5 mL Motor has an intuitive graphical interface that displays Home() Empty the syringe • Stall detector the status of a running experiment in real-time.

Page 12 J-KEM Scientifi c Toll-free: (800) 827-4849 Fax: (314) 863-6070 www.jkem.com [email protected] Syringe Pump Ordering Information

Programmable Syringe Pump, SYR-1200, with Computer Controller Description Cat # Price Single position syringe pump with stand-alone computer controller (shown on p.10). 120 Vac version SYR-1200 $2640.00 System requires the selection of one syringe and valve (below) for operation. 230Vac, CE approved SYR-1240 2660.00 Dual position syringe pump with stand-alone computer controller (shown on p. 10). 120 Vac version SYR-2200 4150.00 System requires the selection of two syringes and valves (below), one for each pump. 230Vac, CE approved SYR-2240 4170.00 Programmable Syringe Pump, SYR-1400, with KEM-Pump Software Single position syringe pump with KEM-Pump software for PC control (shown on p.11). 120 Vac version SYR-1400 $2180.00 System requires the selection of one syringe and valve (below) for operation. 230Vac, CE approved SYR-1440 2190.00 Dual position syringe pump with KEM-Pump software for PC control (shown on p.11). 120 Vac version SYR-2400 3695.00 System requires the selection of two syringes and valves (below), one for each pump. 230Vac, CE approved SYR-2440 3710.00 Syringe Pump Options Built-in digital temperature controller. Controls the temperature of an attached piece of equipment to 0.1o C. SYR-DTC $520.00 Data logging, PC control, 120 V, 1200 watts I/O Package. Includes 3 high current outputs (170 mA, 24 Vdc), 3 digital TTL inputs, 1 analog input (8 bits, 0-5 Vdc). SYR-I/O 390.00 Control solenoid valves or read input sensors, all under program control. Includes internal power supply. Programmable 120 V outlet. Turns equipment On/Off under program control. 3 amps @ 120 Vac (12 amp available) SYR-120V 155.00 Syringes (one needed for each syringe module) Custom Syringe Pumps Description Cat # Price 10 µL glass syringe with Tefl on plunger SPGS-10 $196.50 Program controlled 25 µL glass syringe with Tefl on plunger SPGS-25 112.50 distribution valve provides 32 selectable ports of 50 µL glass syringe with Tefl on plunger SPGS-50 112.50 reagent or reactor access. 100 µL glass syringe with Tefl on plunger SPGS-100 102.50 250 µL glass syringe with Tefl on plunger SPGS-250 102.50 500 µL glass syringe with Tefl on plunger SPGS-500 102.50 1.0 mL glass syringe with Tefl on plunger SPGS-1000 102.50 1.25 mL glass syringe with Tefl on plunger SPGS-1250 102.50 2.5 mL glass syringe with Tefl on plunger SPGS-2500 102.50 5 mL glass syringe with Tefl on plunger SPGS-5000 102.50 10 mL glass syringe with Tefl on plunger SPGS-10000 102.50 25 mL glass syringe with Tefl on plunger SPGS-25000 157.50 50 mL glass syringe with Tefl on plunger SPGS-50000 196.50 Tefl on Distribution Valves (one needed for each syringe module) 3-Port distribution valve (syringe + 3 addressable ports) SPDV-3 $132.50 4-Port distribution valve (syringe + 4 addressable ports) SPDV-4 150.00 6-Port distribution valve (syringe + 6 addressable ports) SPDV-6 180.00 8-Port distribution valve (syringe + 8 addressable ports) SPDV-8 196.50 Tefl on Tubing & Fittings Startup Kit. 20 feet 1/8” OD tubing, 12 nuts & ferrules SP-SK1 $120.00 System sequentially delivers 20 reagents and solvents, or mixture of any combination of reagents. PC Startup Kit. 100 feet 1/8” OD tubing, 24 nuts & ferrules SP-SK2 380.00 Heated syringe software runs 1024 unattended experiments with data Startup Kit. 20 feet 1/16” OD tubing, 12 nuts & ferrules SP-SK3 92.00 logging and fl ushing of the reactor cell. Startup Kit. 100 feet 1/16” OD tubing, 24 nuts & ferrules SP-SK4 290.00 Dimensions: SYR1200 12”x3.5”x13” (HxWxD) Flow rates: 0.75 µL/min to 375 mL/min SYR2400 12”x7”x13” (HxWxD) Accuracy: 0.33% CV, full stroke Pressure Limit: 80 psi Precision: 0.007% full stroke

Microfl uidic reaction system provides continuous delivery of 24 reagents and Eight independent half-size Custom pump drives 4-48 syringes in solvents to a heated reactor. PC control automates 1000 reaction combinations syringe pumps parallel. See page 8.

J-KEM Scientifi c Toll-free: (800) 827-4849 Fax: (314) 863-6070 www.jkem.com [email protected] Page 13 Reaction Controller Automate the addition of reagents based on: • Time • Temperature • pH • Pressure

The Reaction Controller has all the features and runs all of the programs of the model SYR-1200 syringe pump (page 10). In addition, the Reaction Controller has integrated thermocouple and pH inputs expanding its capabilities to add reagents not just as a function of time, but also, temperature, and pH. Common applications include maintaining a constant solution pH during the course of a reaction, or adjusting the addition rate of a reagent as a function of reaction temperature. J-KEM also offers custom programming at no additional charge to meet the unique requirements of your application.

Let J-KEM design a fully automated reaction system for your lab. We automate reaction setups involving Custom.... weighing, reagent delivery, temperature control, mixing, pressure control, and any other feature. Combined with custom Windows software, J-KEM can make the perfect reaction system for your research needs.

Programmable Reaction Controller Description Cat # Price Reaction Controller with Thermocouple Input INF-RC-T $3460.00 Syringe pump with thermocouple input adds multiple reagents as a function of time and temperature. Logs all reaction parameters to internal memory or PC. Requires the selection of one syringe and valve from page 13 for operation. Reaction Controller with Thermocouple and pH Input INF-RC-TP 3520.00 Syringe pump with thermocouple and pH inputs adds multiple reagents as a function of time, temperature and/or pH. Logs all reaction parameters to internal memory or PC. Requires the selection of one syringe and valve from page 13. Options Digital Temperature Controller Channel SYR-DTC $520.00 Digital temperature controller built into the Reaction Controller regulates the temperature of the addition reaction. Digital Pressure Monitor SYR-PSI 600.00 Monitors the pressure of the addition process. Use to add reagents as a function of pressure or to stop addition if pressure reaches a user set safe limit. Selectable pressure ranges. Contact J-KEM for pressure range options. Examples of Custom Reactors

Catalyst Testing Station Controller prepares and charges reactor with substrate and reagents to Four place, sequentially run Titer Point Device independently heated 1000 unattended and cooled reaction reactions Automatically fi nds the testing catalyst titer point of fatty acids. system. PC control with data logging. longevity. Controls 4 independent reactions: · 0.01o C resolution Catalyst activity o Temperature range: -20 · Temperature (-20 to 100 C) · Programmable heating to 100o C is determined by · Stir rate and torque and cooling rates the addition rate · Addition sequence and rate of · Range: -20 to 100o C of base needed 12 reagents to maintain a · PC control and data logging constant pH.

Page 14 J-KEM Scientifi c Toll-free: (800) 827-4849 Fax: (314) 863-6070 www.jkem.com [email protected] From the beginning, J-KEM has worked to be part of the research community, rather than Something just a supplier to the research community. That’s why J-KEM offers substantial Academic discounts on every item we sell, because we believe that supporting the next generation of researcher is part of our corporate responsibility. J-KEM’s Continuous Flow Reactor unusual continues that commitment by supplying the high quality instruments that are needed for from a scientifi c research today. At the time this catalog was printed, our continuous fl ow reactor was still in development, but even in development, its performance and features so signifi cantly exceeded instrument company those of any other fl ow reactor that we decided to provide a preview of what’s coming. Continuous Flow Reactor J-KEM’s continuous fl ow reactor can be confi gured to operate in either of two modes, reaction discovery mode or preparative synthesis mode. In discovery mode, a homogeneous mixture of reaction materials are loaded into a sample injection loop which are then injected into the fl ow reactor. The reactants fl ow through the reactor being pushed forward by a continuous stream of clean solvent. While the reactants from the fi rst injection are in the reactor, the reactants for a second injection are being measured out and mixed by a robotic workstation that both prepares reactants for injection and acts as a fraction collector for the reaction products as they elute. Up to 128 reactions can be fully automated without requiring operator intervention. In discovery mode, 50 - 100 mg of products are typically produced in each experiment.

Fully automated operation runs up to 128 unattended reactions • Prepares reactant mixtures and loads the sample loop • Controls timing of reactant injections and product collection • Program control of fl ow rate and reactor temperature

J-KEM’s continuous fl ow reactor can also be confi gured to run in preparative mode to produce gram quantities of reactants. In prep mode, the reactants are continuously pumped into the reactor in the desired ratios by adjusting the fl ow rate of the two reactant pumps. This method was used to run the reaction shown at the left, which resulted in the preparation of 1.94 g of the aryl amine during a 3.5 hour run.

Reactor Features • Multiple reactor options: - Stainless steel, Inconel, PEEK, PTFE - Tube OD’s of 1/16” and 1/8” - Tube ID’s from 0.02” to 0.14” - Reactor volumes from 1 mL to 20 mL • Flow rates from 0.01 to 5.0 mL/min • High pressure (4000 psi) pump • Temperature range from RT to 300o C • Back pressure regulators from 100 to 1000 psi • Manual or fully automated operation

J-KEM Scientifi c Toll-free: (800) 827-4849 Fax: (314) 863-6070 www.jkem.com [email protected] Page 15 Personal Reaction Station MedChem Heat, Cool, Refl ux Built-in Synthesis in a Parallel • Add reagents Magnetic Format • Sample reactions Stirring in an inert atmosphere The Personal Reaction Station has every feature needed for lead development and high throughput applications. The reactor provides precise temperature control, powerful magnetic stirring, and an inert atmosphere for each reaction tube. Reactions Remove individual reactions are run in 50 mL glass without disturbing the atmosphere in any other tube tubes that fi t inside a heated and cooled reactor base. Six built-in magnetic stirrers provide uniform stirring even for viscous and heterogeneous reactions. A refl ux condenser plate surrounds the midsection of each reaction tube providing for a continuous refl ux with no cross contamination or solvent loss. Reactors connect to an inert gas manifold through separate needle valves and quick disconnect fi ttings, allowing individual reactors to be removed without disturbing the atmosphere in other reactor. All reactors have Tefl on septum needle ports for adding reagents and for sampling the reactor content.

Custom reactor with inputs for For reaction volumes from 0.5 to 8 thermocouple and mL, J-KEM offers a limited volume reagent addition reactor and heat transfer ring. tube for each Provides homogeneous heating and reactor. refl ux for small volume reactions.

Personal Reaction Station Description Cat # Price Personal Reaction Station Includes reactor with built-in magnetic stirrers, twelve 50 mL 120 Vac version: PRS-120R $2385.00 glass reaction tubes, six Tefl on reactor plugs, septum fi ttings and magnetic stirring bars. Requires Model PRS-T digital temperature/stirring controller. 230 Vac version, CE: PRS-230R 2395.00 Digital Temperature and Stir Rate Controller for Personal Reaction Station. Controller adjusts 120 Vac version: PRS-T-120 684.00 both the stirring rate and reaction temperature. Digital controller provides precise temperature regulation (±0.1o C), temperature ramping, and J-KEM enhanced RS232 serial communications for remote controller and data logging applications. 230 Vac version, CE: PRS-T-230 694.00 Reduced Volume Kit Tapered glass reaction tubes for solution volumes from 0.5 to 8 mL. Reduced volume tube fi ts PRS-RDK 230.00 in a heat transfer ring for homogeneous heating. Includes six glass reaction tubes and six heat transfer rings. 50 mL Glass Reaction Tubes Glass reaction tubes with Tefl on lined caps. (Package of 36) KPS50-GT 147.50 10 mL Glass Reaction Tubes Reduced volume glass reaction tubes with Tefl on lined caps. (Package of 6) PRS10-GT 187.50 Evaporator Head for Personal Reaction Station Evaporator injects streams of nitrogen gas into each reaction tube. PRS-VAP 680.00 External Temperature Probe Insert Tefl on probe into one reactor to regulate solution temperature. PRS-RTD 122.00 Replacement Tefl on Septa Septa for syringe injection port. (Package of 48) PRS-SEP 32.00 Replacement Septum Fittings Threaded fi tting secures Tefl on septum into reaction head. (Package of 12) PRS-SF 28.50 Replacement Reactor Plug Tefl on plug fi ts inside reaction tube forming an air tight seal. Includes cap PRS-TP 45.00 Replacement Inert Gas Lines Inert gas delivery lines and quick connect fi ttings. (Package of 6) PRS-IL 15.00 Tefl on Stirring Bars Tefl on coated ‘star’ stirring bar optimized for PRS tubes. (Package of 6) PRS-MSB 58.50

o o Reactor Specifi cations: Temperature range: -80 to 130 C Temperature variation: ±0.5 C Stirring speed: 60-1000 rpm Condenser effi ciency: 2% loss of CH2Cl2 after 7 days at refl ux

Page 16 J-KEM Scientifi c Toll-free: (800) 827-4849 Fax: (314) 863-6070 www.jkem.com [email protected] · Glass reactors KEM-Prep Parallel Reactor · Inert atmosphere Heat, Cool, Refl ux Add reagents - Sample reactions - in an inert atmosphere · Temperature range: -80 to 130o C · Built-in condenser refl uxes 24 reactions · Inert gas swept interior

KEM-Prep reactor shown with model KLS-150/T temperature controller

KEM-Prep Jr. Classical Synthesis in a Parallel Format The KEM-Prep and KEM-Prep Jr. reactors are ideally suited for lead development or high throughput applications. Reactions are run in either 25 or 50 mL glass reaction tubes which fi t inside the heated and cooled reactor base. A refl ux condenser plate surrounds the midsection of each tube enabling a continuous refl ux with no cross contamination or solvent loss. Reactors are maintained in an inert atmosphere while reagents are added through a Tefl on septa port. Mixing is achieved by mounting the reactor on J-KEM’s bench top shaker. The KEM-Prep reactor holds 24 KEM-Prep reactor shown with reaction tubes while the KEM-Prep Jr. holds 6 tubes. optional solvent evaporator

KEM-Prep Reactors Description Cat # Price KEM-Prep Reactor for 25 mL reaction Tubes. Includes 24-position KEM-Prep reactor, 36 glass reaction tubes, and KPS25-120R $2990.00 Tefl on septum sheet. Requires a KLS temp. controller (see below). 120 V. Available for 230 V, CE approved KEM-Prep Reactor for 50 mL reaction Tubes. Includes 24-position KEM-Prep reactor, 36 glass reaction tubes, and KPS50-120R 2990.00 Tefl on septum sheet. Requires a KLS temp. controller (see below). 120 V. Available for 230 V, CE approved KEM-Prep Jr. Reactor for 25 mL reaction Tubes. Includes 6-position KEM-Prep Jr. reactor, 12 glass reaction tubes, KPJ25-120R 2380.00 and Tefl on septum sheet. Requires a KLS temp. controller (see below). 120 V. Available for 230 V, CE approved KEM-Prep Jr. Reactor for 50 mL reaction Tubes. Includes 6-position KEM-Prep Jr. reactor, 12 glass reaction tubes, KPJ50-120R 2380.00 and Tefl on septum sheet. Requires a KLS temp. controller (see below). 120 V. Available for 230 V, CE approved Temperature Controllers Digital Temperature Controller for KEM-Prep Reactor. Temperature ramping and 0.1o C regulation. RS232 optional KLS-150 $520.00 Digital Temperature Controller with 100 Hour Timer for KEM-Prep Reactor. Temperature ramping and 0.1o C KLS-150/T 678.00 regulation. 100 Hour timer turns heating On/Off at user set time. RS232 serial port for PC control is optional. Accessories Evaporation Head for KEM-Prep Reactor Evaporator fi ts on top of reactor base and directs a jet of nitrogen gas into KPS-VAP $1480.00 each of the 24 reactors through a stainless steel needle. Needle height above solvent front is adjustable. Evaporation Head for KEM-Prep Jr. Reactor Evaporator fi ts on top of reactor base and directs a jet of nitrogen gas KPJ-VAP 680.00 into each of the 6 reactors through a stainless steel needle. Needle height above solvent front is adjustable. Replacement Tefl on Septum Sheet for KEM-Prep reactor. KPS-SEP 59.25 Replacement Tefl on Septum Sheet for KEM-Prep Jr. reactor. KPJ-SEP 37.25 25 mL Glass Reaction Tubes. Package of 36 tubes with Tefl on lined caps. KPS25-GT 147.50 50 mL Glass Reaction Tubes. Package of 36 tubes with Tefl on lined caps. KPS50-GT 147.50 Shakers and Mounting Plates Digital Bench Top Shaker for mixing KEM-Prep reactor (see p. 19). Requires KPS-MP or KPJ-MP mounting plate. BTS-3500 $1985.00 Analog Bench Top Shaker for mixing KEM-Prep reactor (see p. 19). Requires KPS-MP or KPJ-MP mounting plate. BTS-1500 1495.00 KEM-Prep Shaker Mounting Plate. Secures the reactor to the bench top shaker platform for mixing. KPS-MP 120.00 KEM-Prep Jr. Shaker Mounting Plate. Secures the reactor to the bench top shaker platform for mixing. KPJ-MP 120.00

J-KEM Scientifi c Toll-free: (800) 827-4849 Fax: (314) 863-6070 www.jkem.com [email protected] Page 17 Reaction Blocks Three Styles of Reaction Blocks to choose from: Reaction Block Index Single temperature zone blocks p. 18 Multi-temperature zone blocks p. 22 Custom reaction blocks p. 20 Reaction block accessories p. 19

Heated Heated & Cooled Refl ux Built-in internal heater Built-in heater and Three layer block. for rapid and internally milled Heated bottom layer, homogeneous heating coolant fl ow path cooled top layer, and surrounding every vial. insulating middle layer. Cooling is provided by Cooled top (condenser) a circulating chiller. maintains refl ux in a capped vial. Cooling can be added to the heated bottom layer (optional) to provide heating, cooling, and Reaction Block refl ux in the same Evaporators block.

Reaction blocks are an effi cient way to provide uniform heating and cooling for multiple reactions. Evaporators fi t on top of the reaction block directing jets of nitrogen gas Temperature homogeneity of ±1o C into each individual vial. Heating and · gently shaking the block evaporates Temperature range: -80 to 130o C · solvents in a fraction of the time needed · Effi cient mixing, even for heterogeneous mixtures by other methods.

Heated Reaction Blocks Description Cat # Price Heated block for 2 mL vial size (12 x 32 mm vial). 96 vial positions in an 8 x 12 array RB-2 $845.00 Heated block for 4 mL vial size (15 x 45 mm vial), 1 dram. 96 vial positions in an 8 x 12 array RB-4 845.00 Heated block for 8 mL vial size (17 x 60 mm vial), 2 dram. 96 vial positions in an 8 x 12 array RB-8 845.00 Heated block for 20 mL vial size (28 x 61 mm vial). 63 vial positions in a 7 x 9 array RB-20 845.00 Heated and Cooled Reaction Blocks Heated and Cooled block for 2 mL vial size (12 x 32 mm vial). 96 vial positions in a 8 x 12 array RBC-2 $1194.00 Heated and Cooled block for 4 mL vial size (15 x 45 mm vial), 1 dram. 96 vial positions in a 8 x 12 array RBC-4 1194.00 Heated and Cooled block for 8 mL vial size (17 x 60 mm vial), 2 dram. 96 vial positions in a 8 x 12 array RBC-8 1194.00 Heated and Cooled block for 20 mL vial size (28 x 61 mm vial). 63 vial positions in a 7 x 9 array RBC-20 1194.00 Refl ux Reaction Blocks Note: The vial used with a refl ux block is twice the size of the block itself. For example, the 4 mL refl ux block (RBR-4) uses an 8 mL vial to provide 4 mL sample volume and 4 mL head space for condensation. Refl ux block for 2 mL vial size (15 x 45 mm vial). 96 vial positions in a 8 x 12 array RBR-2 $1960.00 Refl ux block for 4 mL vial size (17 x 60 mm vial), 1 dram. 96 vial positions in a 8 x 12 array RBR-4 1960.00 Refl ux block for 8 mL vial size (21 x 70 mm vial), 2 dram. 63 vial positions in a 7 x 9 array RBR-8 1960.00 Refl ux block for 20 mL vial size (28 x 95 mm vial). 63 vial positions in a 7 x 9 array RBR-20 1960.00 Optional cooling channels added to heated bottom layer. To order, add the suffi x “-BCP”. Example: “RBR-8-BCP” -BCP 475.00 Evaporators for Reaction Blocks Evaporator for 96 position blocks. Fits RB-2, RB-4, RB-8, RBC-2, RBC-4, RBC-8, RBR-2, RBR-4 RBV-96 $965.00 Evaporator for 63 position blocks. Fits RB-20, RBC-20, RBR-8, RBR-20 RBV-63 965.00 Reaction blocks for custom vial sizes or confi gurations are available. Contact J-KEM for information.

Page 18 J-KEM Scientifi c Toll-free: (800) 827-4849 Fax: (314) 863-6070 www.jkem.com [email protected] The Complete Reaction Block System Consists of:

+ + +

1) Any style reaction block 2) Bench top shaker 3) Reaction block thermocouple 4) Temperature controller

J-KEM offers both a digital and analog shaker specifi cally designed to handle the high temperatures and Rotary Shakers weights of our reactions blocks. 10% discount on shakers when ordered with a reaction block Rotary Bench Top Shakers Description Cat # Price Digital bench top shaker for reaction blocks. Digital speed control. BTS-3500 $2295.00 Continuous operation or 100 hr. timer, unbalance sensor. 120 V Analog bench top shaker for reaction blocks. Rotational speed set via BTS-1500 1635.00 front panel dial. Continuous operation or 1 hr. timer. 120 V Analog bench top shaker. Same as BTS-1500, 230 V, CE approved BTS-1524 1635.00

Specifi cations: BTS-3500 BTS-1500 Rotational speed: 15-500 rpm 40-400 rpm Digital BTS-3500 Orbital diameter: 0.75” 0.75” Load capacity: 35 pounds 35 pounds Timer duration: 100 hr. 1 hr. 5 year Unbalance sensor: Automatic stop None RS232 serial interface: Yes No warranty Certifi cations: UL, cUL, CE UL, cUL, CE Dimensions: 17.4” x 13.5” x 6.4” Weight: 35 lb. Analog BTS-1500

All J-KEM controllers precisely regulate reaction block temperatures. The 200-Series controllers Temperature (page 32) are always a good choice providing 0.1o C regulation of any heater, including reaction blocks. Controllers The Model 150 controller is an affordable alternative which also provides 0.1o C regulation of reaction blocks. The Model 150 is available with or without a 100 hr. timer to turn heating On/Off at a user set time. Optional RS232 serial communications for PC control and data logging (page 36).

Digital Temperature Controllers. Model 150 Description Thermocouple Range (oC) Cat # Price Model 150 temperature controller with ramp-to-setpoint Type T -200 to 250 150-T $512.00 digital meter. 120 V, 1200 watts. Type J 0 to 800 150-J 512.00 Type K -50 to 1200 150-K 512.00 Model 150/Timer temperature controller with 100 hr. timer Type T -200 to 250 150/Timer-T 660.00 to turn heating On/Off at user set time. Ramp-to-setpoint Type J 0 to 800 150/Timer-J 660.00 digital meter. 120 V, 1200 watts. Type K -50 to 1200 150/Timer-K 660.00

Reaction Block Thermocouple Recirculating Chillers Circulating chillers attach to the cooling Reaction Block Thermocouples ports on cooled Description Cat # Price reaction blocks to Spring loaded bayonet RBTC-T 64.00 provide the cooling to thermocouple connects to RBTC-J 64.00 run chilled reactions. mating port on the reaction Temperature as low block providing continuous RBTC-K 64.00 o and reliable temperature as -90 C. readings of shaking blocks. See page 24 for a complete selection.

J-KEM Scientifi c Toll-free: (800) 827-4849 Fax: (314) 863-6070 www.jkem.com [email protected] Page 19 Custom Reaction Blocks

J-KEM makes custom reaction blocks for virtually any application. Examples of custom blocks from J-KEM.

Features include: · Built-in stirring · Multiple temperature zones · High temperatures · Multiple vial sizes

Three temperature zone block (240o C) secured to a low profi le shaker. Used to test the effectiveness of surfactants for oil/water separations

250 mL Erlenmeyer fl ask block

KEM-Lab Reactor (see p. 23) with insert Two temperature zone block blocks for 4 vial sizes for multiple vial sizes

Large block for 15 quart jars

See-through block for crystallization studies in glass titer plates. High temperature High temperature block (300o C) in insulating frame inside insulated frame

Six temperature zone block for SPS synthesis columns

Two temperature zone block for heating & cooling inside insulating frame

Heated & cooled reaction block with High temperature block inside insulating inserts to fi t a selection of vial sizes frame with inert gas cover

Page 20 J-KEM Scientifi c Toll-free: (800) 827-4849 Fax: (314) 863-6070 www.jkem.com [email protected] Custom Solutions for Demanding Chemistry Even more to feed the imagination

Block on hotplate stirrer Refl ux block for multiple vial sizes High temperature see-through block for 4 mL for organic chem lab vials. Heated & cooled design.

Four temperature zone Peltier regulated block for 125 mL bottles

Heater with built-in digital controller for DNA hybridization

Two heated & cooled pockets built into Gilson rack

Oven for Half liter block with four deep digital over-head stirrer Saponifi cation reactor with high pressure stainless well titer and digital controller for steel reaction tubes. Insulated reactor inside plates. formulations testing explosion resistant housing Cover not shown

Heated Heated & cooled block to block inside mate with insulating multi- frame position 16-position microtiter plate heater stirrer

J-KEM Scientifi c Toll-free: (800) 827-4849 Fax: (314) 863-6070 www.jkem.com [email protected] Page 21 Multi-Temperature Zone Reaction Blocks

Multi-zone reaction blocks allow independent temperature control of each block position. Each block can be a different style (heated, cooled, refl ux) and can fi t different size vials. Multi-zone reaction blocks are an indispensable tool for parallel synthesis, process development, and formulations research.

6-Position reaction block with 6-position temperature controller 4-Zone block heats 4 titer plates each · 2, 4, or 6 Independent temperature zones 4-position block with 3 vial sizes · Heat, cool, and refl ux capability · Multiple vial sizes 6-zone block for 2 vial sizes. Four heated/cooled positions and 2 heated only positions Ordering a Multi-Zone Reaction Block There are literally hundreds of confi gurations for 2, 4, and 6-position 1) Do you want a block with 2-, 4-, or 6-temperature zones? reaction block systems. For this reason, it’s necessary to request a quote 2) What size vial does each block (temperature zone) fi t? that assigns a unique product number to your unique block. To receive 3) What style (heated, heated/cooled, refl ux) is each block position? a quote, call or e-mail a description that answers these questions: 4) Any custom features? Vial spacing, hole depth, special shapes? E-mail: [email protected] Phone: (800) 827-4849 or (314) 863-5536 Fax: (314) 863-6070 Prices The price of a multi-zone block depends on the block style selected for each of the temperature zones (the vial size does not matter). The price of a Number of Vial Positions in Each Zone of a block can be calculated from this price list. Multi-Zone The number of vials that fi t in each Reaction Block Multi-Temperature Zone Reaction Blocks temperature zone depends on the vial Description Price size and the block style selected. Two zone reaction block Base price for two heated zones: $1620.00 Vial Size: 2 mL 4 mL 8 mL 20 mL For each cooled zone add: 320.00 2-Zone Heated style 96 72 48 32 For each refl ux zone add: 820.00 Reaction Cooled style 96 48 48 24 Four zone reaction block Base price for four heated zones: 2425.00 Block Refl ux style 48 48 24 24 For each cooled zone add: 230.00 Heated style 72 42 42 12 For each refl ux zone add: 650.00 4-Zone Reaction Cooled style 72 42 24 12 Six zone reaction block Base price for six heated zones: 2765.00 Block Refl ux style 24 24 12 12 For each cooled zone add: 230.00 For each refl ux zone add: 650.00 6-Zone Heated style 45 28 28 9 Reaction Cooled style 25 19 19 6 Multi-Position Temperature Controllers Block Refl ux style 19 19 8 6 Two zone digital temperature controller. Ramp-to-setpoint, USB $925.00 Four zone digital temperature controller. Ramp-to-setpoint, USB 1820.00 Six zone digital temperature controller. Ramp-to-setpoint, USB 2475.00

Multi-Temperature Pocket Blocks Multi-temperature zone pocket blocks fi t aluminum inserts that fi t various vial sizes and microtiter plates. · Transfer inserts between a robotic deck and the heated pocket block. · Purchase insert blocks for any vial size.

Page 22 J-KEM Scientifi c Toll-free: (800) 827-4849 Fax: (314) 863-6070 www.jkem.com [email protected] KEM-Lab Parallel Reactors Compact * Convenient * Precise Temperature Control KEM-Lab reactors are an ideal addition to a research laboratory. The perfect tool for synthesis, formulations, and incubations · Compact design minimizes the bench space needed · Temperature ramping for both heating and cooling · Temperature range: -80 to 130o C · Multiple styles: heating, cooling, and refl ux

KEM-Lab shaker provides vigorous mixing for KEM-Lab reactors.

KEM-Lab Reactors for: Titer plates * Vials * Custom racks Three styles of reactors to choose from: Heated * Heated & Cooled * Refl ux Heated KEM-Lab Reactors Heated & Cooled KEM-Labs Refl ux KEM-Labs Reactor Reactor Reactor fi ts (vial dim.) (# of vials) fi ts (# of vials ) fi ts (# of vials) Description Cat # Price Cat # Price Cat # Price 2 mL vial (12 x 32 mm) (24) KLS-2-H $725.00 2 mL vial (24) KLS-2-C $980.00 2 mL vial (18) KLS-2-R $1320.00 4 mL vial (15 x 45 mm) (24) KLS-4-H 725.00 4 mL vial (24) KLS-4-C 980.00 4 mL vial (16) KLS-4-R 1320.00 8 mL vial (17 x 60 mm) (20) KLS-8-H 725.00 8 mL vial (20) KLS-8-C 980.00 8 mL vial (12) KLS-8-R 1320.00 16 mL vial (21 x 70 mm) (15) KLS-16-H 725.00 16 mL vial (15) KLS-16-C 980.00 20 mL vial (28 x 61 mm) (12) KLS-20-H 725.00 20 mL vial (12) KLS-20-C 980.00 20 mL vial (6) KLS-20-R 1320.00 Shallow well titer plate (1 plate) KLS-SW-H 725.00 Shallow (1 plate) KLS-SW-C 980.00 Deep well titer plate (1 plate) KLS-DW-H 725.00 Deepwell (1 plate) KLS-DW-C 980.00 All reactors are for 120 V use. J-KEM’s glass titer plate (1 plate) KLS-GP-H 725.00 Glass (1 plate) KLS-GP-C 980.00 230 V reactors available on request. KEM-Lab Reactor Shaker & Accessories KEM-Lab bench top shaker Provides vigorous mixing for KEM-Lab reactors. Specifi cations: 100 to 2000 rpm. KLS-HD $1845.00 Continuous and pulsed shaking modes. Weight limit: 4 pounds. 120 V. Dimensions: 16” x 7” x 8.75” (WxDxH) Septum cover plate provides an air-tight seal and needle access port for each vial in the reactor to add reagents or KLS-SC-# 210.00 sample reactions. Includes a Tefl on faced septum sheet. To specify the cover, replace the ‘#’ in the catalog number with the number of vial positions in the block. Example: KLS-SC-12 fi ts the KLS-20-H, KLS-20-C, and KLS-8-R reactors. Replacement septum sheet Tefl on faced sheet for septum cover. KLS-SEP 32.80 Digital Temperature Controllers Digital temperature controller for KEM-Lab reactors. Controller provides 0.1o C KLS-150 $520.00 regulation of any KEM-Lab reactor. 120 V Optional RS232 communications. Digital temperature controller with 100 hour timer. Same as KLS-150 but includes a KLS-150/T 678.00 100 hour timer to turn heating Off (or On) at a user set time. Optional RS232 port. Replacement power cable between reactor and KLS controller. KLS-Cable 85.00 KEM-Lab Reactor Evaporators Glass Plates for KLS-GP Reactors Evaporation head Fits on top of the J-KEM’s glass plates are individual tubes reactor to direct a jet of nitrogen gas held rigidly in a polypropylene holder. Ideal into each vial. Apply mild heating for compound storage or chemical syntheses from the reactor to rapidly evaporate that require the chemical resistance of glass. even high boiling point solvents. To The KLS-GP reactor has milled positions specify the evaporator, replace the surrounding each tube providing outstanding ‘#’ in the catalog number with the vial temperature homogeneity. Volume discounts. positions in the block. Example: KLS-VAP-20 fi ts KLS-8-H and Plate with 0.5 mL reactors GP1 $45.95 KLS-8-C reactors. Plate with 1.0 mL reactors GP2 45.95 Tefl on cap mat. Solid plug in each tube for air tight seal KLS-CM 25.50 Cat # KLS-VAP-’#’ Price: $860.00 Tefl on cap mat. Hollow plug for needle penetration KLS-CMX 25.50 Circulating Chillers/Heaters

J-KEM’s circulating chiller/heaters are optimized for use with J-KEM’s reaction blocks and parallel equipment. With both pressure and suction pumps, these circulators generate higher pumping pressures to provide rapid heating and cooling of attached equipment. All circulators have digital temperature entry, PID control for 0.05o C regulation, and over-temperature protection. Models with RS232 serial ports allow PC data logging and control of temperature ramps.

Quality · Dual pressure & suction pumps provide high in the Details coolant fl ow rates for rapid cooling · Inert gas purge fi tting blankets the cooling fl uid to prevent condensation build-up · Easy temperature entry · Large digital display

-40.0o C chiller with J-KEM’s KEM-Prep Programmable Digital Standard reactor Controller Controller Controller

Programmable - Stores 10 programs of 50 steps each Yes No No Remote temperature probe option Yes No No Graphic LCD readout Yes Yes No Dual display of set point and actual bath temperature Yes Yes No Serial communications (RS232) Yes Yes No Includes PC control software (data logging, temp. ramps) Yes Yes No Dual pressure and suction pumps Yes Yes No Temperature stability 0.01o C 0.01o C 0.05o C Circulating Chillers Temperature Cooling power at: Pressure and Flow Bath Circulator Series Range (o C) 0o -10o -30o Suction Pumps Rate Capacity Weight Cat # Price Model 9100 Standard -20 to 150 140 100 -- No 15 lpm 6 liters 60 lb. 9100-E $2379.00 Digital -20 to 200 watts Yes 30 lpm 9100-SC 3042.00 Programmable -20 to 200 Yes 30 lpm 9100-P 3771.00 Model 9500 Standard -30 to 150 480 360 100 No 15 lpm 13 liters 140 lb. 9500-E 2784.00 Digital -30 to 200 watts Yes 30 lpm 9500-SC 3319.00 Programmable -30 to 200 Yes 30 lpm 9500-P 4048.00 Model 9700 Standard -40 to 150 450 380 160 No 15 lpm 13 liters 150 lb. 9700-E 3369.00 Digital -40 to 200 watts Yes 30 lpm 9700-SC 3904.00 Programmable -40 to 200 Yes 30 lpm 9700-P 4633.00 Circulating Chillers Accessories Heat Transfer Fluid. Dynatherm is a low viscosity fl uid with a high heat capacity for rapid heat transfer. Dynatherm $125.00 Compatible with water condensation that contaminates other transfer fl uids. Range: -50 to 218o C. 4 L bottle. Cryogenic Transfer Hose. Flexible cryogenic transfer hose connects chiller to external equipment. Length: 5 feet. RC-CTH 570.00 Temperature range: -90 to 300o C. Terminal fi tting: 1/8” NPTM (same as reaction blocks). Price for 1 pair. Quick Connect Fittings. Stainless steel fi ttings for rapid connection of cryogenic hose to equipment. Includes a set of RC-QCC 294.00 4 fi ttings (1 each on the ends of the inlet and outlet hoses, and 1 each on the inlet and outlet of the equipment). Chiller Specifi cations The heat transfer fl uid used with the chiller Dimensions Power Fluid Tech Note is as important as the chiller itself. A good Series (LxWxH) (@ 120 V) Connections transfer fl uid must remain non-viscous at 9100 16.8” x 8.3” x 22.5” 1100 watts 1/4 NPTF the lowest possible temperature for effi cient cooling. J-KEM’s 9500 17” x 15.5” x 24.8” 1100 watts 1/4 NPTF Dynatherm retains its low viscosity even at -50o C. 9700 17” x 15.5” x 24.8” 1100 watts 1/4 NPTF

Page 24 J-KEM Scientifi c Toll-free: (800) 827-4849 Fax: (314) 863-6070 www.jkem.com [email protected] Miniature Overhead Stirrer Power - More power than stirrers 10 times its size and weight!

- Weighs less than 1 pound! Convenience - Hand-sized · The light weight of the motor makes it easy to assemble and align the stirrer with the reaction fl ask · Side mount clamp on digital speed controller

- Sparkless - Sealed housing Safety - 14 Vdc motor

Compare the Value Manufacturer Model Max Torque Weight Price J-KEM OHS-1 91 in-oz 0.95 pounds $955.00 Cole-Parmer Servodyne (R-50003-20) 70 in-oz 11 pounds 1,980.00 Arrow Agitator 40 in-oz 10 pounds 836.00 Effi cient stirring of a 5 L fl ask IKA Eurostar 85 in-oz 9 pounds 1,775.00 Glas-Col HST30N 101 in-oz 20 pounds 2,052.00

Overhead Stirrer Description Cat # Price Specifi cations Complete System. Includes the motor, digital speed controller, and chuck for OHS-1 $955.00 Input voltage: 100-120 Vac 10 mm stirring rod. Voltage to motor: 14 Vdc max Motor only for OHS-1 stirrer. Includes 10 mm stirring rod chuck. OHS-1M 640.00 Maximum torque: 91 in-oz Digital speed controller only for miniature OHS-1 motor. OHS-DSC 320.00 Rotational speed: 10 - 380 rpm Replacement inserts to secure 10 mm stirring rods in motor chuck. (Package of 6) OHS-P10 12.50 Rotational control: 1 rpm Chuck for 6 mm stirring rods. Chuck replaces the standard 10 mm chuck. OHS-6C 43.40 Custom Laboratory Controllers

We’re glad to work with our customers to make one-of-a-kind instruments for temperature and pressure control. Shown are examples of recent projects.

Six position temperature controller with three independent digital vacuum regulators

Four position temperature controller designed to fi t on the front face of a Sixteen position temperature controller research hood

J-KEM Scientifi c Toll-free: (800) 827-4849 Fax: (314) 863-6070 www.jkem.com [email protected] Page 25 Solid Phase Synthesis Reactor No Fully Automated SPS Reactor Mechanical Valves Solvent is held in the reactor by computer controlled nitrogen back pressure. Single key stroke commands provide the functionality to: · Set up a new reaction · Mix the reactants and resin · Filter & wash the resin · Cleave and collect fi nal products

The SPS reactor works by pressurizing the reactor base with nitrogen gas until it exactly offsets the pull of gravity. In this way, solvent can be added to a single reactor with none of it dropping through the frit. As reactors are sequentially fi lled, the SPS computer regulator precisely controls the fl ow of nitrogen to maintain the reactor’s back pressure to +-0.001 psi. Using nitrogen back pressure to hold solvent in the reaction tube eliminates the need for Gas coming up through mechanical valves or other mechanical devices which prevents automation of the SPS process. Reactions are the bottom frit to mixed by placing the reactor on a bench top shaker, or by increasing the pressure in the base to cause continuous promote mixing or intermittent bubbling up through the frit mixing the resin and reactants. Reaction setup, mixing, washing, and fi ltration are accomplished by a single key stroke on the computer pressure regulator. Can be combined with J-KEM’s Eclipse robot for fully automated, multi-step SPS reactions.

Automation Ready See J-KEM’s solid phase synthesis robot on page 3.

Solid Phase Synthesis Reactor. Basic Components Description Cat # Price Reactor Base. Polypropylene base fi ts collection block and secures reactor top plate. SPS-TB $2450.00 Reactor Support Plate with luer fi ttings to secure 48 SPS reactors. SPS-SP48 748.00 Reactor Support Plate with lure fi ttings to secure 96 SPS reactors SPS-SP96 940.00 Sample Collection Block positions sample collection tubes beneath reaction tube outlets. SPS-CB 750.00 Collection blocks are customized to fi t your vial or tube. Contact J-KEM with specifi cations. SPS Pressure Regulator. Computerized controller regulates the back pressure applied to SPS-REG 2750.00 SPS reactor with reactor the reaction tubes. Automates reaction setup, resin washing, and sample collection. refl ux heater and digital temperature controller Pressure Proportioning Valve for SPS pressure regulation. For 48 position reactor. PSV-5 485.00 Pressure Proportioning Valve for SPS pressure regulation. For 96 position reactor. PSV-5TEK 987.00 Waste Valve fi lters reaction tubes and sweeps wash and reaction solvents to waste. SPS-WV 285.00 Inlet Gas Pressure Regulator. High fl ow rate nitrogen gas inlet pressure regulator. SPS-HCR 130.00 SPS Reactors Fritted SPS Reactor, 6 mL capacity, PP column with 20 µm PE frit. (Package of 100) SPS-RX6 $122.50 Fritted SPS Reactor, 12 mL capacity, PP column with 20 µm PE frit. (Package of 100) SPS-RX12 145.00 Fritted SPS Reactor, 35 mL capacity, PP column with 20 µm PE frit. (Package of 100) SPS-RX35 161.25 Reactor Refl ux Heater surrounds each reactor Fritted SPS Reactor, 60 mL capacity, PP column with 20 µm PE frit. (Package of 100) SPS-RX60 193.50 to provide heating to the reaction solvent and cooling Optional SPS Components to the top half of the reactor. Reactor Refl ux Heater. Heats the bottom half of each reaction tube, and cools the top half SPS-RB $1880.00 with a chilled condenser plate to create a sustained refl ux inside the reaction tubes. Reactor Port Plugs. Male luer plug seals unused reactor positions. (Package of 12) SPS-PP 59.90 Replacement O-ring for reactor base. Tefl on impregnated AFLAF. SPS-ORING 56.00 Short Reactor Base. Useful for robotic systems to minimize height of reactor. SPS-SB 1720.00 Inert Gas Reactor Cover. Creates an inert atmosphere for all reactors, septum port access. SPS-EC 1680.00 SPS Concentrator Components Concentrator for 48-position SPS system directs a jet of N2 gas into each collection tube. SPS-CC48 $1350.00 Sample concentrator cover Concentrator for 96-position SPS system directs a jet of N2 gas into each collection tube. SPS-CC96 1390.00 Nitrogen Gas Heater warms the N2 to promote faster evaporation. Includes controller (p. 29) NGH-120 2220.00

Page 26 J-KEM Scientifi c Toll-free: (800) 827-4849 Fax: (314) 863-6070 www.jkem.com [email protected] KEM-Vap Solvent Evaporator Evaporate solvents from: · Deepwell plates · Vial racks · Gilson racks · Custom Racks

Evaporates both volatile and nonvolatile solvents

Acetone • DMSO • TFA Fast DMF • Water Effi cient Solvent Evaporation

The KEM-Vap Solvent Evaporator uses heated nitrogen gas and variable vacuum pressures to rapidly evaporate volatile and nonvolatile solvents in the same evaporator. The evaporator cover directs a jet of nitrogen gas into each cell of a titer plate or vial in a vial rack for uniform and SC4 Gilson rack evaporator consistent evaporations. For nonvolatile solvents, a combination of vacuum and heated nitrogen removes solvents in a fraction of the time needed when vacuum or heated gas is used alone. Made from stainless steel and ultra high density polypropylene the evaporator is not harmed by organic or aqueous solvents. Custom evaporators made on request.

KEM-Vap SOLVENT EVAPORATOR Description Cat # Price SC5 Single plate evaporator Solvent concentrator base for 4 deep well SC1 $2285.00 plates. Solvent concentrator base for 4 shallow well SC3 1115.00 Nitrogen gas heater plates. Solvent concentrator base for 1 Gilson rack. SC4 2380.00 Solvent concentrator base for 1 deep well plate. SC5 1115.00 Need Custom Solvent Evaporators? Insert blocks for SC1 to elevate shallow well SC-IN1 325.00 plates for evaporation. (Set of 4) Solvent evaporator cover for SC1 & SC3. SC10 1640.00 For 96-position titer plates. Solvent evaporator cover for SC1 & SC3. SC11 1640.00 For 48-position titer plates. Solvent evaporator cover for SC1 & SC3. SC12 1640.00 For 24-position titer plates. Contact J-KEM KEM-Lab Solvent evaporator cover for SC4. SC13 1640.00 to design evaporators Solvent evaporator cover for SC5. SC15 970.00 a solvent on page 23 For 96-position titer plates. evaporator for High capacity vacuum solvent trap. Dry ice SC20 185.00 any rack or trap with 1000mL receiving fl ask. application Reaction block Nitrogen gas heater. Includes digital NGH-120 2220.00 evaporators on p. 18 temperature controller. See p. 29 for details.

J-KEM Scientifi c Toll-free: (800) 827-4849 Fax: (314) 863-6070 www.jkem.com [email protected] Page 27 Laboratory Safety Instruments

The Lab Safety Controller combines all the features of J-KEM’s Digital Temperature Lab Safety Controller Monitor and Water Flow Monitor, then adds a temperature limit controller into a single versatile instrument. Plug any piece of equipment into the monitor, USB Communications & then if the water fl ow rate falls below the user set level, or the reaction GLP/GMP software temperature goes above or below the set limits, outlet power is turned off NEW until the controller is manually reset. The controller also disconnects power following recovery from a power failure. USB communications and free KEM-Net software provide GLP/GMP data and alarm logging.

Description TC Type Cat # Price Lab Safety Controller. 120 V, 1800 watts. T LS-120T $595.00 Requires a fl ow sensor. J LS-120J 595.00 KLS-120K 595.00 Lab Safety Controller. 230 V, 2300 watts. LS-230K 615.00 Flow sensor. Flow rate: 0.1 to 2.5 L/min WFM-01 220.00 Flow sensor. Flow rate: 1 to 10 L/min WFM-02 230.00 Flow sensor. Flow rate: 2 to 30 L/min WFM-03 230.00 Protects against: • Coolant fl ow failure Water shut off valve. Turns off fl ow during an alarm 250WV 158.50 • Over-temperature condition Digital Alarm Outlet. Open collector (170 ma) outlet WFM-OC 32.00 • Under-temperature condition - Protects against fl ask breaking or TC falling out of the fl ask. Specifi cations: Dim. 3.25” x 5.25” x 7.25” (H x W x D). USB 2.0

Digital Temperature Monitor Monitors and displays the temperature of an attached piece of equipment on a bright LED display. Built-in USB 2.0 serial communications and free KEM-Net data logging software (page 37) provides remote USB Communications & temperature monitoring and records time & temperature data to a GLP/GMP compliant NEW GLP/GMP software log fi le. Kem-Net provides email notifi cation of an over or under-temperature condition. Large digital display 0.1o C Resolution Optional audible alarm

Description TC Type Range (o C) Cat # Price Digital Temperature Monitor T -200 to 250 DM120-T $375.00 120 Vac input. USB communications J 0 to 800 DM120-J 375.00 with KEM-Net data logging software K -50 to 1200 DM120-K 375.00 Digital Temperature Monitor T -200 to 250 DM230-T 385.00 230 Vac input. USB communications J 0 to 800 DM230-J 385.00 with KEM-Net data logging software K -50 to 1200 DM230-K 385.00 Specifi cations: 120 or 230 Vac input, 50 watts USB 2.0 Dim. 2.5” x 3.75” x 5.4” (H x W x D)

Precisely monitors the fl ow rate of water through a condenser, water bath, or other piece of Water Flow Monitor equipment. If the fl ow rate falls below the minimum rate set by the user (i.e. loss of pressure, broken hose), power is turned off to the monitor’s output receptacle and any equipment plugged into it. Power remains off until being manually reset. The optional water shut off valve stops water fl ow during an alarm condition preventing a fl ooded lab. With safety as its primary goal, the J-KEM Water Flow Monitor measures the actual water fl ow rate, rather than back pressure as in commonly measured by lower quality instruments. • Digital sensor measures • Optional audible actual coolant fl ow rate and digital alarms

Description Cat # Price Water fl ow monitor. 120 V, 1800 watts. Requires a fl ow sensor. WFM-120 $345.00 Water fl ow monitor. 230 V, 2300 watts. Requires a fl ow sensor. WFM-230 365.00 Flow sensor. Flow rate: 0.1 to 2.5 L/min WFM-01 220.00 Flow sensor. Flow rate: 1 to 10 L/min WFM-02 230.00 Flow sensor. Flow rate: 2 to 30 L/min WFM-03 230.00 Water shut off valve. Turns off water fl ow during an alarm. 250WV 158.50 Prevents heating accidents Audible Alarm. Alarm (70 dB) sounds during under fl ow condition. WFM-AA 65.00 due to water fl ow failures Digital Alarm Outlet. High current (170 ma) open collector output. WFM-OC 32.00 Specifi cations: Dimensions: 2.5” x 3.75” x 5.4” (H x W x D)

Page 28 J-KEM Scientifi c Toll-free: (800) 827-4849 Fax: (314) 863-6070 www.jkem.com [email protected] Laboratory Safety Instruments

Trinity Power Controller Replace an existing electrical outlet • Convenience of a built-in variac Solid state electronics makes this variac the perfect instrument for research, and is especially useful in teaching labs. Safety features include sparkless solid state regulation of voltage for oil • Frees up bench space baths, heating mantles, heat lamps, and many other devices. Offered in two confi gurations, the • Solid state design Trinity-1 replaces an existing receptacle for installation directly in hoods or other outlets. The • Affordable price Trinity-2 comes in its own case with an attached power cord. Both the Trinity-1 and Trinity-2 are offered with and without a built in analog voltage meter. Trinity Power Controller Installs Built-in in Hood Meter Cat # Price* Yes** Yes Trinity-1M $138.00 Yes** No Trinity-1P 118.00 No Yes Trinity-2M 148.00 No No Trinity-2P 128.00 Specifi cations: 120vac, 5 amps, 600 watts Installs * Academic and volume discounts Trinity-1 in hood Trinity-2 ** Requires 1.625” junction box depth

Nitrogen Gas Heater Maximum Gas Temperature as a Function of Flow Rate J-KEM’s Nitrogen Gas Heater regulates the temperature of nonfl ammable gases providing Maximum Temperature (oC) an intrinsically safe heat source for safety critical laboratory applications. An ideal Air Flow Voltage: 120 V 230 V instrument for solvent evaporation or for any heating application where a traditional heater (L/min) 700 watts 900 watts 2000 watts is unsafe or inconvenient to use. Includes a digital temperature controller for 50 820 820 820 0.5o C regulation of outlet gas temperature. A minimum fl ow rate of 1 liter/minute must 75 590 660 820 be maintained when power is applied to the heater. To avoid burning out the heater 150 330 400 820 element, an optional fl ow switch can be built into the heater to turn power off when gas 225 230 280 570 fl ow falls below the minimum safe level. 375 150 175 350 Intrinsically safe heating, even for fl ammable substances

Nitrogen Gas Heater Description Cat # Price Heater with digital controller, 120 Vac. 700 watt heater core. NGH-120 $2220.00 Heater with digital controller, 120 Vac. 900 watt heater core. NGH-130 2250.00 Heater with digital controller, 230 Vac. 2000 watt heater core. NGH-230 2275.00 Accessories Flow switch turns heating off if air fl ow falls below a minimum safe rate. NGH-FS 610.00 Specifi cations: Temperature range: See chart above Minimum fl ow range: 1 liter per minute Fittings: 3/8” female NPT

Handheld Meter & These versatile meters provide convenient temperature readings from a variety of Data Logger thermocouples. Features include two thermocouple inputs, large dual temperature displays, data logging and automatic MIN/MAX temperature storage. Data can be transferred in real-time or after a run is complete on the optional PC interface.

Feature HHM-20 HHM-40 Hand Held Temperature Meters Thermocouples T, J, K, E T, J, K, E Description Cat # Price o o Resolution 0.1 0.1 Dual channel hand held meter HHM-20 $185.00 Data points stored 25 1000 Dual channel meter with extended Optional printer No Yes memory to store 1000 data points HHM-40 260.00 Scale oF and o C Yes Yes Automatic MIN/Max Yes Yes Hand Held Meter Options Built-in stand Yes Yes RS232 interface for PC data logging HHM-232 125.00

J-KEM Scientifi c Toll-free: (800) 827-4849 Fax: (314) 863-6070 www.jkem.com [email protected] Page 29 Digital Vacuum Regulator Features: * No Mercury

· 100% digital pressure entry and control · Wetted parts are 100% stainless steel and Tefl on · Vacuum ramping feature eliminates bumping · USB port and free software for PC control

Resists: · All organic solvents · Acids · Bases · Water

The Digital Vacuum Regulator is an ideal instrument for laboratory vacuum regulation. Connect the regulator to any vacuum pump or vacuum source and then to any piece of equipment to regulate pressure in most cases to ± 1 torr. A pressure ramp feature (standard) evacuates equipment at a user defi ned rate to eliminate bumping due to solvent degassing or over-evacuation. The vacuum regulator is ideally suited for large volume distillations, rotary evaporators and vacuum chambers. The DVR-200 is not recommended for small volume distillations or applications which involve a continuous purge with gas. These are better performed by J-KEM’s Precision Vacuum Regulator, the DVR-1000. Two Styles of Regulator to Choose From Recover > 99% of solvent DVR-200 The DVR-200 is designed for continuous vacuum sources, such as from rotary evaporators oil-fi lled vacuum pumps, aspirators, or systems that are “always on”, like in-house vacuum systems. The DVR-200 regulates pressure by opening and closing a valve that separates the vacuum DVR Pressure Solvent Time to Percent source from the system being evacuated. In most cases, the Solvent (mm Hg) Volume Dryness Recovery DVR-200 is the best choice. Ether 475 torr 340 mL 14.6 min 99.6% CH2Cl2 300 torr 360 mL 21.9 min 99.8% DVR-280 CH2Cl2 100 torr 255 mL 5.9 min 99.5% The DVR-280 is designed for use with diaphragm vacuum EtOAc 90 torr 316 mL 17.0 min 99.9% pumps. In some systems, pressure is regulated by turning on and Toluene 50 torr 273 mL 15.7 min 99.4% off the vacuum pump itself. The DVR-280 extends the life of diaphragm pumps by not exposing the diaphragm to full vacuum A Note About Quality pressures when starting, which increases pump life by 100%. J-KEM uses the highest quality components available. For example, most vacuum controllers use a silicone fi lled vacuum transducer (because they cost less), but J-KEM uses a stainless steel diaphragm transducer. Also, rather than a standard vacuum valve NEW!! USB + with Viton seals, J-KEM uses a custom stainless steel valve with Tefl on seals. These, Free KEM-Net software. (see p. 37) and other enhancements provide the chemical resistance needed in chemistry laboratories.

Digital Vacuum Regulators and Monitors Description Cat # Price Vacuum Regulator, Model DVR-200. Includes built-in SS transducer. 120V DVR-200 $1175.00 Vacuum Regulator, Model DVR-300. Same as DVR-200 but for 230V. CE Approved. DVR-300 1195.00 Vacuum Regulator, Model DVR-280. SS transducer and pump controller. 120V DVR-280 1280.00 Vacuum Regulator, Model DVR-380. Same as DVR-280 but for 230V. CE Approved. DVR-380 1295.00 Vacuum Regulator with large capacity valve for large volume equipment. Call 1560.00 Digital Vacuum Monitor. Continuous display of system pressure, no regulation. 120V DVM-100 920.00 Digital Vacuum Monitor. Same as DVM-100 but for 230V. CE Approved. DVM-140 940.00 Vacuum Regulator Accessories Stainless Steel Needle Valve. Improves regulation in small pieces of equipment. DVR-PNV $108.50 Analog pressure output. External 0-20 mV analog output. Useful for data logging. DVR-JH 95.00 Condenser body for dry ice condenser. 35/25 joint. JCE-1000 268.00 Dry ice trap Condenser receiving fl ask. 1000 mL fl ask with 35/25 joint. MTE-1000 65.00 JCE-1000 Condenser receiving fl ask. 2000 mL fl ask with 35/25 joint. MTE-2000 72.00 Specifi cations: 120 & 230 Vac @ 100 watts. Vacuum fi ttings: 1/8” NPTM. Dim. 3.4” x 5.4” x 7.4” (HxWxD) * Academic discounts. Warranty: Electronics: 2 yr; transducer and vacuum valve: 6 mo., but void if due to chemical buildup. Page 30 J-KEM Scientifi c Toll-free: (800) 827-4849 Fax: (314) 863-6070 www.jkem.com [email protected] Precision Vacuum & Pressure Regulators

Precise regulation of ±0.1 torr of volumes as small as 1 mL · Perfect for vacuum distillations Automatically compensates for leaks in the · equipment under test Maintains constant precise pressure, even in · systems with a continuous gas purge

Standard Features: · 16-Step programmable pressure ramp Serial communication for PC control and · logging

Custom Features: 0.1 Torr Regulation - No Mercury Custom programming to meet any research · requirement J-KEM’s computer (built-in) controlled vacuum and pressure regulators maintain · Add a temperature control channel. pressure to 0.1 torr in test instruments with volumes as small as 1 mL. Built Add User programmable digital and analog · inputs and outputs from J-KEM’s Infi nity Computer, this series of instruments can be customized to Use the built-in Infi nity computer to automate automate virtually any laboratory or quality control task involving the regulation · a complex test sequence or any process of vacuum or pressure. The DVR-1000 regulates vacuums, the DPR-1100 involving pressure control regulates positive pressures, and the DDR-1200 regulates both vacuum and positive pressures.

Precision Vacuum and Pressure Regulators Description Cat # Price Digital Vacuum Regulator. Precise regulation of vacuum pressures in the range of DVR-1000 $2980.00 0.1 to 760.0 torr (atm pressure). Requires the selection of one PSV valve (below) Digital Pressure Regulator. Precise regulation of positive pressures in the range DPR-1100-# 3145.00 of 0 psi (atm pressure) to 50 psi. The maximum pressure of the controller is user Specifi cations: selectable. Replace the ‘#’ in ‘DPR-1100-#’ with the selected maximum pressure. Ranges: 1, 5, 15, 30, 50 psi. Requires the selection of one PSV valve (below). Gage Transducer transducer is standard, but absolute is available on request. Diaphragm: Stainless steel Dual Range Vacuum & Pressure Regulator. Precisely controls both vacuum and DDR-1200-# 3615.00 Accuracy: DVR-1000: 0.1% positive pressures. The DDR-1200 is built with a dual range pressure transducer DPR-1100: 0.25% capable of accurately measuring pressures from full vacuum to the pressure limit of DDR-1200: 0.25% the transducer selected. The maximum pressure of the controller is user selectable. Proof Pressure: 200% Replace the ‘#’ in ‘DDR-1200-#’ with the selected maximum pressure above ATM. Ranges: 15 and 35 psi. Requires the selection of two PSV valves (below), one for Controller vacuum and one for pressure regulation. Contains an absolute pressure transducer. Regulation: 0.015% of range Back-Fill Option. The DVR-1000 and DPR-1100 can be equipped to operate a OPT-DV 220.00 Resolution: 0.1 torr or 0.01 psi second valve used to back fi ll the evacuated or pressurized reactor. Requires the selection of a second PSV valve (below). Vapor Path Materials: Stainless steel and Tefl on Stainless Steel Proportioning Valves Ramp Rates: The optimal PSV value depends on the exact conditions of the procedure. The volume guides below are helpful 100 torr/sec to 0.1 torr/hr. for closed systems. For applications with a continuous purge of gas, call J-KEM for assistance. Serial Communications: RS232 Proportioning Valve. Microfl ow proportioning valves, call to discuss your application. PSV-Micro Call (RS485 or USB on request) Proportioning Valve. For reactor volumes: 1 mL to 2 L Cv: 0.033 Orifi ce: 0.040” PSV-2 $485.00 Power: 100 watts. Proportioning Valve. For reactor volumes: 25 mL to 4 L Cv: 0.055 Orifi ce: 0.055” PSV-3 485.00 Proportioning Valve. For reactor volumes: 100mL to 22L Cv: 0.068 Orifi ce: 0.063” PSV-4 485.00 Fittings 1/4” SS Compression fi ttings Proportioning Valve. For reactor volumes: 1 L to 50 L. Cv: 0.12 Orifi ce: 0.093” PSV-5 485.00 Proportioning Valve. Large capacity valve. Cv: 0.37 Orifi ce: 0.147” PSV-5TEK 987.00 Warranty: Proportioning Valve. Large capacity valve. Cv: 0.7 Orifi ce: 0.234” PSV-6 1097.00 Electronics: 2 years. Transducer and proportioning Proportioning Valve. Large capacity valve. Cv: 1.3 Orifi ce: 0.316” PSV-7 1097.00 valve is 6 mo. but void if failure Proportioning Valve. Large capacity valve. Cv: 2.0 Orifi ce: 0.375” PSV-8 1097.00 is due to chemical buildup.

J-KEM Scientifi c Toll-free: (800) 827-4849 Fax: (314) 863-6070 www.jkem.com [email protected] Page 31 Digital Temperature Controllers

The Model 210 is J-KEM’s most compact, research-grade controller, yet packed with 1200 watts of power. Model 210 Suffi cient for heating mantles up to 5 L in size and most laboratory ovens, hot plates, reaction blocks and other heaters. Contains J-KEM’s patented power control computer which provides 0.1o C regulation of anything. NEW!! 230VAC, CE approved USB port and Free — 0.1o C Regulation & Display — · NIST traceable KEM-Net data logging Model 310 available · Advanced PID algorithm & control software Controller Only Complete System § Thermocouple Temperature o Cat # Price* Cat # Price* Type Range ( C) 210-T $840.00 210-T-S $925.00 T -200 to 250 210-J 840.00 210-J-S 925.00 J 0 to 800 210-K 840.00 210-K-S 925.00 K -50 to 1200 210-Pt 850.00 210-Pt-S 995.00 RTD -200 to 400 Specifi cations: 120vac, 10 amps, 1200 watts. Dim. 3.25” x 5.25” x 7.4” (HxWxD) * Academic and volume discounts available. 2 Year warranty § Complete system includes: controller, Tefl on TC, TC cord, and adapter (see p. 33)

Same power and versatility as the Model 210, but also contains a 100 hour digital timer to turn Model 210/Timer heating OFF (or ON) at a user specifi ed time. A new safety feature automatically disconnects power from the heater following recovery from a power failure. Contains J-KEM’s patented power control computer which provides 0.1o C regulation of anything. NEW!! NIST traceable USB port and Free o · KEM-Net data logging — 0.1 C Regulation & Display — · Advanced PID algorithm & control software Controller Only Complete System § Thermocouple Temperature o Cat # Price* Cat # Price* Type Range ( C) 210/Timer-T $935.00 210/Timer-T-S $1020.00 T -200 to 250 210/Timer-J 935.00 210/Timer-J-S 1020.00 J 0 to 800 210/Timer-K 935.00 210/Timer-K-S 1020.00 K -50 to 1200 210/Timer-Pt 945.00 210/Timer-Pt-S 1090.00 RTD -200 to 400 Specifi cations: 120vac, 10 amps, 1200 watts. Dim. 3.25” x 6.7” x 6” (HxWxD) * Academic and volume discounts available. 2 Year warranty § Complete system includes: controller, Tefl on TC, TC cord, and adapter (see p. 33)

1. Power Regulation J-KEM’s original power control computer is replaced by a next generation New in 2009 microprocessor. The power control computer is J-KEM’s patented technology that adjusts power to the heater 2048 times per second resulting in 0.1o C regulation.

At the heart of J-KEM’s 200-Series 2. USB Communications PC communications and free controllers is a new, high KEM-Net software enables remote PC control, GLP/GMP compliant data speed microprocessor that collection, and multi-temperature ramps built in an Excel-like table. performs 3 functions: 3. Upgradable Programming Software modules can be uploaded to the processor, at no charge, adding new capabilities to the controller. For example, automatic detection of exothermic reactions. You may not see the exotherm in this plot (and it was a big one), but the microprocessor does. You can’t see it because as it occurred, the temperature controller stopped powering the heater to compensate for the heat being generated by the reaction.

Page 32 J-KEM Scientifi c Toll-free: (800) 827-4849 Fax: (314) 863-6070 www.jkem.com [email protected] The Model 250 has both heating and cooling outlets for maximum versatility. Two heating outlets supply Model 250 1800 watts of power for large equipment and heating mantles up to 22 L. The third outlet (1800 watts), normally used for cooling, is programmable to supply power below, above, or at the setpoint. Contains J-KEM’s patented power control computer which provides 0.1o C regulation of anything. NEW!! NIST traceable USB port and Free o · KEM-Net data logging — 0.1 C Regulation & Display — · Advanced PID algorithm & control software Controller Only Complete System § Thermocouple Temperature o Cat # Price* Cat # Price* Type Range ( C) 250-T $935.00 250-T-S $1025.00 T -200 to 250 250-J 935.00 250-J-S 1025.00 J 0 to 800 250-K 935.00 250-K-S 1025.00 K -50 to 1200 250-Pt 945.00 250-Pt-S 1095.00 RTD -200 to 400 Model 250 Accessories Coolant valve turns On/Off fl ow in cooling applications. Cat# 250WV $142.50 Specifi cations: 120vac, 15 amps, 1800 watts. Dim. 3.5” x 7.75” x 9.25” (HxWxD) * Academic and volume discounts available. 2 Year warranty § Complete system includes: controller, Tefl on TC, TC cord, and adapter (see p. 33)

Designed for processes requiring an extra measure of safety. The Model 260/Timer Model 260/Timer disconnects outlet power if the process temperature exceeds the setpoint by a user specifi ed amount, or following recovery from a power failure. Power remains off until the controller is manually reset. Over temperature is signalled by both an indicator lamp and an audible alarm. Contains a 100 hour digital timer to turn heating OFF (or ON) when the time expires. The Model 260 has two power outlets (1800 watts) for large equipment or heating mantles up to 22 L. Contains J-KEM’s patented power control computer which provides 0.1o C regulation of anything. NEW!! — 0.1o C Regulation & Display — 230VAC, CE approved NIST traceable USB port and Free · KEM-Net data logging Model 360 available · Advanced PID algorithm & control software

Controller Only Complete System § Thermocouple Temperature o Cat # Price* Cat # Price* Type Range ( C) 260/Timer-T $1175.00 260/Timer-T-S $1265.00 T -200 to 250 260/Timer-J 1175.00 260/Timer-J-S 1265.00 J 0 to 800 260/Timer-K 1175.00 260/Timer-K-S 1265.00 K -50 to 1200 260/Timer-Pt 1185.00 260/Timer-Pt-S 1335.00 RTD -200 to 400 Specifi cations: 120vac, 15 amps, 1800 watts. Dim. 3.5” x 7.75” x 9.25” (HxWxD) * Academic and volume discounts available. 2 Year warranty § Complete system includes: controller, Tefl on TC, TC cord, and adapter (see p. 33)

The Complete System

1. Temperature Types T & K 2. Thermocouple 3. Tefl on Probe 4. Tefl on Coated have the best Controller corrosion resistance Extension Cord Adapter Thermocouple (14/20 joint)

J-KEM Scientifi c Toll-free: (800) 827-4849 Fax: (314) 863-6070 www.jkem.com [email protected] Page 33 Multi-Channel Controllers

Features two temperature controllers in a single cabinet to regulate two independent reactions. The Gemini is among Gemini J-KEM’s most versatile controllers featuring high power outlets and a 100 hour digital timer (on channel 1) to turn heating OFF (or ON) at a user entered time. Features include: over-temperature protection circuits with audible alarms, dual temperature displays, selectable operating modes, double fused, and 100% solid state design. Contains J-KEM’s patented power control computer which provides 0.1o C regulation of anything. Gemini controls TWO independent reactions! NEW!! USB port and Free 230VAC, CE approved NIST traceable KEM-Net data logging — 0.1o C Regulation & Display — · Gemini-CE available · Advanced PID algorithm & control software

Controller Only Complete System § Thermocouple Temperature o Cat # Price* Cat # Price* Type Range ( C) Gemini-T $1365.00 Gemini-T-S $1540.00 T -200 to 250 Gemini-J 1365.00 Gemini-J-S 1540.00 J 0 to 800 Gemini-K 1365.00 Gemini-K-S 1540.00 K -50 to 1200 Gemini-Pt 1375.00 Gemini-Pt-S 1680.00 RTD -200 to 400 Specifi cations: 120vac, 15 amps, 1800 watts total, 1200 watts maximum per channel. Dim. 3.5” x 7.75” x 9.25” (HxWxD) * Academic and volume discounts available. 2 Year warranty § Includes: controller, plus two each of: Tefl on TC, TC cord, and adapter (see p. 33)

Features two independent temperature controllers in a single cabinet to regulate two reactions at the same time. Each Apollo temperature controller channel has a high power outlet and a 100 hour digital timer to turn heating OFF (or ON) at a user set time. Features include: over-temperature protection circuits, dual temperature displays, selectable operating modes, double fused, and 100% solid state design. Contains J-KEM’s patented power control computer which provides 0.1o C regulation of anything. Controls TWO independent reactions! NEW!! USB port and Free — 0.1o C Regulation & Display — · NIST traceable KEM-Net data logging · Advanced PID algorithm & control software Controller Only Complete System § Thermocouple Temperature o Cat # Price* Cat # Price* Type Range ( C) Apollo-T $1515.00 Apollo-T-S $1695.00 T -200 to 250 Apollo-J 1515.00 Apollo-J-S 1695.00 J 0 to 800 Apollo-K 1515.00 Apollo-K-S 1695.00 K -50 to 1200 Apollo-Pt 1535.00 Apollo-Pt-S 1825.00 RTD -200 to 400 Specifi cations: 120vac, 15 amps, 1800 watts total, 1200 watts maximum per channel. Dim. 4” x 8.2” x 9” (HxWxD) * Academic and volume discounts available. 2 Year warranty § Includes: controller, plus two each of: Tefl on TC, TC cord, and adapter (see p. 33)

Because we’ve never met a chemist with too much bench space, the Quad packs four independent temperature The Quad controllers into a single compact unit. Each of the four controller channels has 1200 watts of power, an independent display, and an over-temperature protection circuit. Contains J-KEM’s patented power control o computer which provides 0.1 C regulation of anything. Think of the Quad as a Model 210 on steroids NEW!! USB port and Free 0.1o C Regulation · NIST traceable KEM-Net data logging and Display · Advanced PID algorithm & control software Controller Only Complete System § Thermocouple Temperature o Cat # Price* Cat # Price* Type Range ( C) Quad-T $2355.00 Quad-T-S $2695.00 T -200 to 250 Quad-J 2355.00 Quad-J-S 2695.00 J 0 to 800 Quad-K 2355.00 Quad-K-S 2695.00 K -50 to 1200 Quad-Pt 2355.00 Quad-Pt-S 2955.00 RTD -200 to 400 Specifi cations: 120vac, 15 amps, 1800 watts total, 1200 watts maximum per channel. Dim. 5.25” x 7” x 7.5” (HxWxD) * Academic and volume discounts available. 2 Year warranty § Includes: controller, plus four each of: Tefl on TC, TC cord, and adapter (see p. 33)

Page 34 J-KEM Scientifi c Toll-free: (800) 827-4849 Fax: (314) 863-6070 www.jkem.com [email protected] High Safety Controllers Designed for processes requiring uncompromised safety. The only temperature controller available with a Model 270 built-in, independent, backup controller to guard against heating accidents from equipment failure. The desired temperature is entered into the main temperature controller which regulates heating, and then a high temperature cut-off is entered into the backup limit controller. If the reaction reaches the high temperature limit or a thermocouple breaks, power is turned off to the heater until the controller is manually reset. Both meters independently monitor the reaction temperature. In the event that one meter fails, the other takes over to prevent a heating accident. J-KEM’s design provides independent, 100% redundant control. Contains J-KEM’s patented power control computer which provides 0.1o C regulation of anything. NEW!! USB port and Free * * 0.1o C Regulation & Display * * · NIST traceable KEM-Net data logging · Advanced PID algorithm & control software Controller Only Complete System § Thermocouple Temperature o Cat # Price* Cat # Price* Type Range ( C) 270-T $1530.00 270-T-S $1680.00 T -200 to 250 270-J 1530.00 270-J-S 1680.00 J 0 to 800 270-K 1530.00 270-K-S 1680.00 K -50 to 1200 Specifi cations: 120vac, 15 amps, 1800 watts. Requires a dual element Dim. 3.4” x 7.75” x 9.25” (HxWxD) thermocouple (see below) * Academic and volume discounts available. 2 Year warranty § Includes: controller, dual element Tefl on TC, TC cord, and adapter (see p. 33) High Power Controllers

USB port and Free KEM-NEt data logging NEW!! & control software Three Models of HCC to choose from

HCC 130 Voltage: 110-120 V Power: 30 amps; 3600 watts Description Cat # Price Model HCC-130 controller only. HCC-130-T $1865.00 Requires a dual element thermocouple and HCC-130-J 1865.00 thermocouple extension cord (see below). HCC-130-K 1865.00 HCC 215 Voltage: 208-240 V Power: 15 amps; 3600 watts Model HCC-215 controller only. The line of HCC controllers are HCC-215-T $1890.00 Model HCC designed to power large scale Requires a dual element thermocouple and HCC-215-J 1890.00 equipment with volumes up to 100 L. Built with the same thermocouple extension cord (see below). HCC-215-K 1890.00 uncompromising commitment to safety as our Model 270, the HCC is HCC 230 Voltage: 208-240 V Power: 30 amps; 7200 watts available in 3 models for 120 and 230 volt operations. In addition to Model HCC-215 controller only. HCC-230-T $1985.00 the features of the Model 270, these high power controllers incorporate Requires a dual element thermocouple and HCC-230-J 1985.00 a 100 hour timer to turn heating OFF (or ON) at a user set time. The thermocouple extension cord (see below). HCC-230-K 1985.00 HCC is readily customized to meet unique research or additional safety Dimensions: Temperature range T -200 to 250o C needs. Call for details. Contains J-KEM’s patented power control 5.5” x 12” x 12.5” of all HCC J 0 to 800o C computer which provides 0.1o C regulation of anything. (HxWxD) controllers K -50 to 1200o C Thermocouples for Model 270 and HCC Controllers

Dual element thermocouples contain two independent thermocouples in a single probe. Model 270 and HCC controllers require either 1 dual-element or 2 single-element thermocouples. Tefl on Coated Dual Element Thermocouples Dual Element Thermocouple Extension Cords Probe Thermocouple Diameter (in.) Length (in.) Cat # Price Length Cat # Price Probes listed are 1/8 12 TC270-(*)-18T12 $103.00 10 ft. EXT-10-270-(*) $45.00 Tefl on coated. 1/4 12 TC270-(*)-14T12 115.00 25 ft. EXT-25-270-(*) 70.00 Stainless steel and 1/4 24 TC270-(*)-14T24 137.00 glass probes are * Specify thermocouple type T, J, or K also available. 1/4 36 TC270-(*)-14T36 151.00 Probes of any length are available. * Specify thermocouple type T, J, or K J-KEM Scientifi c Toll-free: (800) 827-4849 Fax: (314) 863-6070 www.jkem.com [email protected] Page 35 Variable Oil Bath Controller Voltage Output The Model 410 is designed for heaters that cannot be operated at 120 Vac, such as some styles of oil baths. The Model 410 maximum output voltage of the Model 410 is selected using the Power Output knob on the front of the controller. Selectable output voltage limits provide precise power and temperature control while protecting low voltage heaters. Contains J-KEM’s patented power control computer which provides 0.1o C regulation of anything. NEW!! USB port and Free — 0.1o C Regulation & Display — Output Voltages of: · NIST traceable KEM-Net data logging 10, 20, 40, 60, 120 Vac · Advanced PID algorithm & control software Controller Only Complete System § Thermocouple Temperature o Cat # Price* Cat # Price* Type Range ( C) 410-T $815.00 410-T-PKG $885.00 T -200 to 250 410-J 815.00 410-J-PKG 885.00 J 0 to 800 410-K 815.00 410-K-PKG 885.00 K -50 to 1200 410-Pt 825.00 410-Pt-PKG 915.00 RTD -200 to 400 Specifi cations: 120vac, 10 amps, 1200 watts. Dim. 3.25” x 5.25” x 7.25” (HxWxD) * Academic and volume discounts available. 2 Year warranty § Complete system includes: controller, stainless steel TC, and TC cord (see p. 33) Economy Temperature Controllers An ideal controller for applications that don’t require the precise regulation of J-KEM’s 200-Series controllers. Model 150 This compact unit packs 1200 watts of power, suffi cient for 5 L heating mantles, many ovens, and other devices. Built with J-KEM’s state-of-the-art PID process controller, but does not contain J-KEM’s power control computer. See comparison below.

· NIST traceable Controller Only Complete System § Thermocouple Temperature o · Advanced PID algorithm Cat # Price* Cat # Price* Type Range ( C) · Ramp-to-setpoint feature standard 150-T $512.00 150-T-S $598.00 T -200 to 250 150-J 512.00 150-J-S 598.00 J 0 to 800 150-K 512.00 150-K-S 598.00 K -50 to 1200 Model 150 Options Cat # Price RS232 Serial Port for PC control and data logging. add “-RS232” $110.00 High Power Output. 1800 watts @ 120 Vac add “-HC” 85.00 Specifi cations: 120vac, 10 amps, 1200 watts. Dim. 2.5” x 3.75” x 5.4” (HxWxD) * Academic and volume discounts available. 2 Year warranty § Complete system includes: controller, Tefl on TC, TC cord, and adapter (see p. 33)

Same power and versatility as the Model 150, but also contains a 100 hour digital timer to turn Model 150/Timer heating OFF (or ON) at a user set time. See comparison to the 200-Series at bottom of page.

· NIST traceable Controller Only Complete System § Thermocouple Temperature o · Advanced PID algorithm Cat # Price* Cat # Price* Type Range ( C) · Ramp-to-setpoint feature standard 150/Timer-T $660.00 150/Timer-T-S $746.00 T -200 to 250 150/Timer-J 660.00 150/Timer-J-S 746.00 J 0 to 800 150/Timer-K 660.00 150/Timer-K-S 746.00 K -50 to 1200 Model 150 Options Cat # Price RS232 Serial Port for PC control and data logging. add “-RS232” $110.00 High Power Output. 1800 watts @ 120 Vac add “-HC” 85.00 Specifi cations: 120vac, 10 amps, 1200 watts. Dim. 2.5” x 4.75” x 5.5” (HxWxD) * Academic and volume discounts available. 2 Year warranty § Complete system includes: controller, Tefl on TC, TC cord, and adapter (see p. 33)

What’s the difference Feature 200-Series 150-Series o o between J-KEM’s 200-Series Temperature regulation 0.1 C 1 C controller and the 150-Series? Smallest regulated volume 0.01 mL 250 mL USB port & software Free Optional J-KEM’s 200-Series controllers have our patented power control computer with technology that provides 0.1o C regulation of any instrument or volume as small as 100 µL. The 150-Series combines a state-of-the-art PID process controller with solid state circuitry to provide unparalleled performance in its price range. The 150-series is ideal for equipment such as reaction blocks, ovens, or heating mantles 500 mL or larger.

Page 36 J-KEM Scientifi c Toll-free: (800) 827-4849 Fax: (314) 863-6070 www.jkem.com [email protected] Serial Communications, PC Control, Data Logging & The J-KEM Advantage

The J-KEM Advantage PC Control with Free Research grade temperature (200-Series) and vacuum regulators contain KEM-Net Software two next-generation FLASH programmable microprocessors.

Processor 1 The Power Control Computer The patented power control computer is the heart of every J-KEM temperature controller. The computer adjusts power to the heater 2048 times per second resulting in 0.1o C regulation of any reaction and virtually eliminates overshoot of the entered setpoint on initial warming.

Processor 2 USB Communications KEM-Net software is included with all USB enabled controllers. The communications Features: processor, new in · Run 16-step temperature and vacuum ramps 2009, implements PC Easy setup using an Excel-like table input control, data logging, and our new web based FLASH Modules. FLASH · Enter setpoints and controller parameters remotely Modules are programs that can be downloaded from J-KEM’s web site to · Real-time graphical display and data logging to Excel your controller at no charge. An example of a FLASH module is the Exo/ · Encrypted data fi le is tamper-proof, meeting GLP and Endo module that automatically quantifi es, then alerts the user when an GMP requirements exothermic reaction is detected. · E-mail alerts of over- & under-temperature alarms PC Control, serial communications, networking, and data logging explained..... J-KEM supports three serial communications standards: USB, RS-232, and RS-485. Each has advantages and limitations.

J-KEM USB This is the standard port on 200-Series temperature controllers and the Digital Vacuum Regulator. Controllers connect to the PC’s USB ports or a USB hub. The advantage of USB is that it’s present on all PCs and supports connecting multiple controllers to a single PC. The only limitation of USB is that cable lengths cannot be longer than 15 feet without using a USB extender (offered below).

RS-232 A hardware RS-232 port is available, but usually not needed. J-KEM’s USB port includes a virtual RS-232 port driver that operates with software utilizing RS-232 communications.

RS-485 has the unique advantage that cable lengths between the instrument and PC can be as long as 4000 feet. For lab USB to RS485 arrangements that require long cable runs, RS-485 is a valuable converter alternative. Contact J-KEM for ordering assistance. J-KEM’s KEM-Comm software is required for RS-485 communications.

Serial Communication Options and Accessories Description Cat # Price USB Extender, 50-Foot. Amplifi er extends USB communications to 50 feet. Includes extender and 50’ cable. USBC-50 $94.00 USB Extender, 100-Foot. Amplifi er extends USB communications to 100 feet. Includes extender and 100’ cable. USBC-100 118.00 USB Extender, 150-Foot. Amplifi er extends USB communications to 150 feet. Includes extender and 150’ cable. USBC-150 142.00 USB 4-Port Hub. Used to connect multiple controllers to a single PC USB port USBH 32.00 RS-232 Port. Physical RS-232 port substituted for the USB port. Add as a suffi x to any controller, Ex: 210-T-RS232 RS232 120.00 RS-485 Port. Physical RS-485 port substituted for the USB port. Add as a suffi x to any controller, Ex: 210-T-RS485 RS485 150.00 USB to RS-485 Converter. Converts a PC USB port to RS-485 with the proper connector style for J-KEM controllers USB-485 140.00 KEM-Comms Software. PC control and data logging software for RS-232 and RS-485 ports. Not needed for USB KEM-Comm 159.00 J-KEM Scientifi c Toll-free: (800) 827-4849 Fax: (314) 863-6070 www.jkem.com [email protected] Page 37 Thermocouples & Accessories NEW! Glass over-coated thermocouples

Note: To read temperatures accurately, the type of the Thermocouple Probe Outer Thermocouple Probe Length thermocouple must match the controller’s type. On a new Type Diameter (in.) Overcoating1 (inches) controller, the type is the letter immediately following the model number: 210 - K - S T ($0) 1/16 ($33.00) Uncoated ($0) 6 ($0) J ($0) 1/8 ($34.00) Tefl on2 ($30.00) 12 ($0) On an existing controller, the thermocouple type is indicated K ($0) 1/4 ($38.00) Glass3 ($40.00) 18 ($11) by the color of the thermocouple receptacle on the front. If the receptacle is: Pt/100 ($60.00) 24 ($15) 36 ($28) BLUE - - - - - you must order a type T thermocouple 1- All sensors are housed in 304 stainless steel sheaths. YELLOW - - you must order a type K thermocouple 2- PFA coating over SS probe. Probes of any BLACK - - - you must order a type J thermocouple Probes are color coded length are 3- Borosilicate glass. Available as 1/4” probe only. available WHITE - - - you must order a type Pt/100 sensor

To determine the Catalog Number of a probe: To determine the Price of a probe: 1. Enter the thermocouple type (T, J, K, Pt/100) Total the dollar value associated with each 2. Enter the outer diameter of the probe (1/16, 1/8, or 1,4) selection made from all four columns 3. Enter the probe over coating (U= Uncoated, T= Tefl on, G= Glass) 4. Enter the length of the probe in inches. Examples: T-1/8-U-12 ...... Price: $0 + 34.00 + 0 + 0 = $34.00 ‰ - ‰ - ‰ - ‰ K-1/4-G-18 ...... Price: $0 + 38.00 + 40.00 + 11.00 = $89.00

Thermocouple Calibration J-KEM offers thermocouple calibration in standard and extended temperature ranges. Calibrated at three points in the stated range with NIST traceable standards and supplied with a certifi cate of calibration. Additional calibration points available on request. Description # of Points Temp. Range Cat # Price Thermocouple calibration, standard temperature range 3 0o C to 150o C STCC $105.00 Additional calibration points in Thermocouple calibration, extended temperature range 3 0o C to 300o C ETCC 150.00 stated range are $35.00 each. Thermocouple calibration, low temperature range 3 -195o C to 300o C LTCC 240.00 Thermocouple Extension Cords Coiled Cord Coiled Thermocouple Cords (see type and connectors below) Catalog Number Extended Length Price Retractable coiled cord saves CC-10-(type)-(connector) 10 feet $26.00 space in crowded hoods. CC-20-(type)-(connector) 20 feet 44.00 26 gauge multi strand wire with PVC insulation. Straight Thermocouple Cords (see type and connectors below) EXT-10-(type)-(connector) 10 feet $17.00 EXT-20-(type)-(connector) 20 feet 30.00 Select a connector Select a connector type style Type Connector Select plug style: SMP or OST Straight Cord Select type: T, J, K, or Pt/100 The cord, controller, and thermocouple Tefl on insulated wire must all be of the same type. for superior chemical Specify: T for a blue plug resistance. 24 gauge J for a black plug single stranded wire. K for a yellow plug Pt/100 for a white plug Ordering Examples: CC-10-T-SMP Style SMP Style OST EXT-20-K-OST Fits all controllers Fits 250, 260,270, HCC

Page 38 J-KEM Scientifi c Toll-free: (800) 827-4849 Fax: (314) 863-6070 www.jkem.com [email protected] Flexible yet rugged thermocouples measure diffi cult to reach spots such as inside Thin Wire Thermocouples heating mantles, ovens, or around curved surfaces. Also useful to measure volumes as small as 100 µL. Thin wire thermocouples adhere to equipment to measure surface temperatures of hot plates, HPLC columns, photolysis or other reactors.

Tefl on Coated Tefl on Coated Thin Wire Thermocouple Thin wire thermocouple (30 gauge; 36” long) completely Description Cat # Price sealed in Tefl on for submersion in solution. Excellent for Type T Tefl on embedded TEF-30-T $89.20 use with small volumes (<100 µL). Inserts through rubber Type K Tefl on embedded TEF-30-K 89.20 septum for airtight seal. Extremely fl exible. Exposed Junction Thin Wire Thermocouple Type T exposed junction TWT-T 28.00 Exposed Junction Type K exposed junction TWT-K 28.00 Tefl on wire (30 gauge; 72” long) exposed junction is Type J exposed junction TWT-J 28.00 ideal for rapid temperature measurement of solids, air, or heating mantles. Not suitable for continuous liquid Longer lengths and other diameters are contact. available on request. Needle Tip Thermocouples

Hypodermic needle thermocouples (17 gauge) are ideal to measure and control the temperature of small volumes and inert reactions. Temperature measuring end of the thermocouple is at the tip, so only the fi rst 2 mm of the probe must have liquid contact for accurate temperature measurement. Forms an air tight seal when inserted through a septum. Needles are sealed on the end for liquid tight applications. Thermocouple Needle Tefl on Coated Needles Uncoated Needles Type Length Catalog # Price Catalog # Price Available in 3.5” and 7” lengths. These stainless steel needles are T 3.5” HN-3.5-T-TEF $93.00 HN-3.5-T $73.00 also available with Tefl on coating. 7.0” HN-7-T-TEF 98.00 HN-7-T 78.00 Each comes with 72 inches of K 3.5” HN-3.5-K-TEF 93.00 HN-3.5-K 73.00 attached Tefl on extension wire. 7.0” HN-7-K-TEF 98.00 HN-7-K 78.00 Tefl on coated J 3.5” HN-3.5-J-TEF 93.00 HN-3.5-J 73.00 NEW needle thermocouples! 7.0” HN-7-J-TEF 98.00 HN-7-J 78.00 Reaction Block Thermocouple

Armored cable thermocouple has a spring loaded bayonet style Thermocouple Type Cat # Price connector for rapid and secure connection to reaction blocks. Type T RBTC-T $64.00 Flexible cable is designed for the constant shaking of reaction Type K RBTC-K 64.00 blocks. Type J RBTC-J 64.00

Thermocouple Adapters Thermocouple OST Male SMP Male Type SMP Female OST Female Price Adapters enable plugging thermocouples with an SMP Type T ADP-T ADA-T $9.75 (small fl at pins) or OST (larger round pins) plug into Type K ADP-K ADA-K 9.75 controllers with the opposite receptacle style. Type J ADP-J ADA-J 9.75

Thermocouple Adapters Tefl on Probe Adapters Probe Joint Replacement O-Rings for Thermocouple Probes Diameter Size Cat # Price Probe Viton (Pk of 12) Kalrez (Each) TEV* (Each) 1/16” 10/18 1016 $32.75 Dia. Cat # Price Cat # Price Cat # Price 1/16” 14/20 1416 34.75 1/16” 1610R $9.00 1/16” 24/40 2416 39.75 1/8” 1810R 9.00 1810RK $40.00 Tefl on probe 1/16” 29/42 2916 43.85 1/4” 1410R 9.00 1410RK 52.00 1410RT $21.00 adapters form 1/8” 10/18 1018 30.75 Replacement Adapter External O-Rings air tight seals 1/8” 14/20 1418 24.95 Joint Viton (Pk of 12) Kalrez (Each) TEV* (Each) between 1/8” 19/22 1918 49.95 thermocouple Size Cat # Price Cat # Price Cat # Price 1/8” 24/40 2418 24.95 probes and 14/20 1420E $9.00 1420EK $46.00 1420ET $21.00 1/8” 29/42 2918 43.85 standard taper 24/40 2440E 9.00 2440EK 56.00 2440ET 22.15 joints. 1/4” 14/20 1414 22.45 29/42 2942E 9.00 2942EK 67.00 2942ET 23.20 Not suitable for 1/4” 24/40 2414 24.95 high vacuums 1/4” 29/42 2914 43.85 * Viton O-ring encapsulated in Tefl on over coating

J-KEM Scientifi c Toll-free: (800) 827-4849 Fax: (314) 863-6070 www.jkem.com [email protected] Page 39 Research Heaters Heating Mantles Series-TM heating mantles Heating mantles are the Series-OS heating have a self-supporting safest method of laboratory mantles can be aluminum shell. The heating because they avoid placed directly on TM mantle is stable on the burn hazards associated top of magnetic bench tops, and with extra with other styles of heaters. stirrers insulation, the exterior Heating mantles uniformly providing remains cool to touch. heat glassware and remain vigorous Maximum internal cool to the touch, even at mixing temperature of 450o C. internal temperatures using a stirring Not suitable for magnetic > 300o C. bar. stirrers.

Heating Mantle 120 Vac Mantles 230 Vac Mantles 120 Vac Mantles 230 Vac Mantles Size (mL) Catalog # Price Catalog # Price Catalog # Price Catalog # Price Wattage 5 OS-5 $116.00 Not available - Not available - Not available - 12 10 OS-10 116.00 Not available - Not available - Not available - 20 25 OS-25 127.00 Not available - Not available - Not available - 30 50 OS-50 122.00 Not available - TM-50 $185.00 Not available - 60 100 OS-100 135.00 Not available - TM-100 190.00 TM-100/230 $196.00 80 250 OS-250 149.00 OS-250/230 $161.00 TM-250 181.00 TM-250/230 201.00 180 500 OS-500 168.00 OS-500/230 179.00 TM-500 218.00 TM-500/230 229.00 270 1,000 OS-1000 188.00 OS-1000/230 199.00 TM-1000 233.00 TM-1000/230 244.00 380 2,000 OS-2000 205.00 OS-2000/230 216.00 TM-2000 242.00 TM-2000/230 253.00 500 3,000 OS-3000 228.00 OS-3000/230 238.00 TM-3000 288.00 TM-3000/230 299.00 500 5,000 OS-5000 278.00 OS-5000/230 290.00 TM-5000 358.00 TM-5000/230 366.00 600 12,000 OS-12000 561.00 OS-12000/230 573.00 TM-12000 668.00 TM-12000/230 678.00 2@650 22,000 OS-22000 665.00 OS-22000/230 680.00 TM-22000 768.00 TM-22000/230 780.00 2@770 50,000 Not available - Not available - TM-50000 1216.00 TM-50000/230 1227.00 3@1000 72,000 Not available - Not available - Not available - TM-72000/230 1387.00 2@2000

® Instatherm Oil Baths * Accommodates a variety of vessel sizes and shapes The intelligent design of the Instatherm oil bath, from Ace Glass, includes features that make it the safest and most reliable oil bath for laboratory use. The metal alloy * Suitable for magnetic stirrers heating element is fused directly to the surface of the glass bath and then covered with a tough silicone rubber layer and a glass insulation layer which serves as both Glass a thermal barrier and protects against physical shock. The bottom of the Electrical connections Instatherm is not heated so the bath can be placed on magnetic stirrers. The Fused-to-glass Instatherm bath can be operated up to Conductive heating fi lm 250o C. Includes power cord. Integral outer Insulation

For maximum versatility, J-KEM recommends the INS-150 and INS-190 oil baths. These baths can be used with any 200-Series temperature controller, which can also be used with any heating mantle (above). Thus, the same controller can be used with either heating mantles or oil baths.

Bath Size Max. Applied Voltage (Dia. x Hght.) Cap., mL (Volts/Amps) Cat # Price Temperature Controller Compatibility 70 x 50 mm 160 mL 20V/5A INS-70 $342.00 Low voltage bath compatible with Model 410 (p. 36) and Trinity controller (p. 29) 100 x 50 mm 340 mL 40V/6A INS-100 379.00 Low voltage bath compatible with Model 410 (p. 36) and Trinity controller (p. 29) 125 x 65 mm 700 mL 40V/8A INS-125 388.00 Low voltage bath compatible with Model 410 (p. 36) and Trinity controller (p. 29) 150 x 75 mm 1200 mL 120V/5A INS-150 424.00 Can be used with any J-KEM Digital Controller. 190 x 100 mm 2600 mL 120V/10A INS-190 490.00 Can be used with any J-KEM Digital Controller. - - - INS-PC 27.00 Replacement power cord for Instatherm oil bath

Page 40 J-KEM Scientifi c Toll-free: (800) 827-4849 Fax: (314) 863-6070 www.jkem.com [email protected] The Road We’re On (together) 1988 Incorporated as J-KEM Electronics. Offering one product, the Model 260 temperature controller, we fi nish our fi rst year with sales of $784.00. 1989 Flush with cash from its fi rst year sales, J-KEM doubles its product line and begins offering the Model 210. Attended the Fall ACS meeting, exhibiting all four of the controllers we owned, then spent sleepless nights worrying how we’d fi ll orders if they came in. J-KEM Scientifi c’s employees gathered around the fi re pole of our fi rst facility, the fi re house. 1990 J-KEM’s fi rst major customer was Dr. James J-KEM appreciates the relationship we’ve had with all of our Zeller of Parke Davis. J-KEM expands its customers. It’s more than just the obvious fact that without you, J-KEM manufacturing area 400% by moving from would not be in business. We appreciate the friendships and the just the corner to occupy the entire basement ideas we’ve received from world class scientists, that without, many (sorry girls about your play house). of our best products wouldn’t exist. Don Korte gave us the idea for the miniature overhead stirrer, Martyn Fordham, the Personal Reaction 1992 Station, Dr. Bruce Hamper the Solid Phase Synthesis Regulator, and the First international sale. Model 210 to Italy. unknown chemist from Abbott who came to our booth at the ACS show to say “I don’t need a temperature controller, I need a vacuum regulator 1993 that works”. This resulted in our Digital Vacuum Regulator. Moved to our fi rst commercial building. Hired our fi rst full time employee (Li, above). Built the fi rst power control computer (8 bits, 4 MHz!!).

1994 - Incorporated as J-KEM Scientifi c 20 Years of Innovation 1995 - Purchased our fi rst building, a 1930’s fi re house.

1998 - First years sales >$1,000,000.

- First robot sold to Dr. Glass 1999 40 MHz microprocessor enables of Zenica. * Exo & Endotherm analysis * USB communications 2000+ - Emphasis in lab automation, * Enhanced safety parallel reactors, and robotics. Pictured are the original 2008 - Staying abreast with advances in (left) and new (right) Model technology: 210-Timer circuit boards In 2008, J-KEM completed the redesign and • Third generation power control The fi rst temperature controller computer implementation of the 3rd generation of its made by J-KEM, sold to Dr. power control computer. The new design • Second generation Syringe Pumps Kurt Moedritzer of Monsanto uses a FLASH programmable microprocessor • Two new robotic designs (Dr. Moedritzer also purchased controller #2. Our fi rst loyal that can be updated with new controller • Custom lab automation features from J-KEM’s web site. instruments and software customer!!) ® KEM Scientifi c Instruments for Science from Scientists

J-KEM Scientifi c, Inc. 6970 Olive Blvd. St. Louis, MO 63130 USA Phone (314) 863-5536 (800) 827-4849 Fax (314) 863-6070 Email [email protected] Web www.jkem.com