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Advances in Biochemical Engineering/Biotechnology SOFTbank E-Book Center Tehran, Phone: 66403879,66493070 For Educational Use. www.ebookcenter.ir 114 Advances in Biochemical Engineering/Biotechnology Series Editor: T. Scheper Editorial Board: W. Babel · I. Endo · S.-O. Enfors · M. Hoare ·W.-S. Hu B.Mattiasson · J. Nielsen · G. Stephanopoulos U. von Stockar · G. T. Tsao · R. Ulber · J.-J. Zhong SOFTbank E-Book Center Tehran, Phone: 66403879,66493070 For Educational Use. www.ebookcenter.ir Advances in Biochemical Engineering/Biotechnology Series Editor: T. Scheper Recently Published and Forthcoming Volumes Engineering of Stem Cells Tissue Engineering II Volume Editor: Martin, U. Basics of Tissue Engineering and Tissue Vol. 114, 2009 Applications Volume Editors: Lee, K., Kaplan, D. Biotechnology in China I Vol. 103, 2007 From Bioreaction to Bioseparation and Bioremediation Tissue Engineering I Volume Editors: Zhong, J.J., Bai, F.-W., Scaffold Systems for Tissue Engineering Zhang, W. Volume Editors: Lee, K., Kaplan, D. Vol. 113, 2009 Vol. 102, 2006 Bioreactor Systems for Tissue Engineering Cell Culture Engineering Volume Editors: Kasper, C., van Griensven, M., Volume Editor: Hu,W.-S. Poertner, R. Vol. 101, 2006 Vol. 112, 2008 Biotechnology for the Future Food Biotechnology Volume Editor: Nielsen, J. Volume Editors: Stahl, U., Donalies, U. E. B., Vol. 100, 2005 Nevoigt, E. Vol. 111, 2008 Gene Therapy and Gene Delivery Systems Protein – Protein Interaction Volume Editors: Schaffer, D.V., Zhou,W. Volume Editors: Seitz, H., Werther, M. Vol. 99, 2005 Vol. 110, 2008 Sterile Filtration Biosensing for the 21st Century Volume Editor: Jornitz, M.W. Volume Editors: Renneberg, R., Lisdat, F. Vol. 98, 2006 Vol. 109, 2007 Marine Biotechnology II Biofuels Volume Editors: Le Gal, Y., Ulber, R. Volume Editor: Olsson, L. Vol. 97, 2005 Vol. 108, 2007 Marine Biotechnology I Green Gene Technology Volume Editors: Le Gal, Y., Ulber, R. Research in an Area of Social Conflict Vol. 96, 2005 Volume Editors: Fiechter, A., Sautter, C. Vol. 107, 2007 Microscopy Techniques Volume Editor: Rietdorf, J. White Biotechnology Vol. 95, 2005 Volume Editors: Ulber, R., Sell, D. Vol. 105, 2007 Analytics of Protein-DNA Interactions Volume Editor: Seitz, H. Vol. 104, 2007 SOFTbank E-Book Center Tehran, Phone: 66403879,66493070 For Educational Use. www.ebookcenter.ir Engineering of Stem Cells Volume Editor: Ulrich Martin With contributions by M. Amit · A. Bosio · S. Donath · M. Geraerts · S. Gerecht I. Gruh · U.A.O. Heinlein · P. Hennemann · V. Huppert · J. Itskovitz-Eldor · R.-K. Li · E. Luong · M. Malchow U. Martin · S. Mitalipov · C.M. Verfaillie · R.D. Weisel D. Wolf · J. Wu · F. Zeng · R. Zweigerdt SOFTbank E-Book Center Tehran, Phone: 66403879,66493070 For Educational Use. www.ebookcenter.ir Editor Professor Dr. Ulrich Martin Hannover Medical School Leibniz Research Laboratories for Biotechnology and Artificial Organs Carl-Neuberg-Str. 1 30625 Hannover Germany [email protected] ISSN 0724-6145 e-ISSN 1616-8542 ISBN 978-3-540-88805-5 e-ISBN 978-3-540-88806-2 DOI: 10.1007/978-3-540-88806-2 Springer Heidelberg Dordrecht London New York Library of Congress Control Number: 2009933990 Springer-Verlag Berlin Heidelberg 2009 This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, roadcasting, reproduction on microfilm or in any other way, and storage in data banks. Duplication of this publication or parts thereof is permitted only under the provisions of the German Copyright Law of September 9, 1965, in its current version, and permission for use must always be obtained from Springer. Violations are liable to prosecution under the German Copyright Law. The use of general descriptive names, registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. Cover design: WMXDesign GmbH, Heidelberg, Germany Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com) SOFTbank E-Book Center Tehran, Phone: 66403879,66493070 For Educational Use. www.ebookcenter.ir Series Editor Prof. Dr. T. Scheper Institute of Technical Chemistry University of Hannover Callinstraße 3 30167 Hannover, Germany [email protected] Volume Editor Dr. Ulrich Martin Hannover Medical School Leibniz Research Laboratories for Biotechnology and Artificial Organs Carl-Neuberg-Str. 1, 30625 Hannover Germany [email protected] Editorial Board Prof. Dr.W. Babel Prof. Dr. S.-O. Enfors Section of Environmental Microbiology Department of Biochemistry` Leipzig-Halle GmbH and Biotechnology Permoserstraße 15 Royal Institute of Technology 04318 Leipzig, Germany Teknikringen 34, [email protected] 100 44 Stockholm, Sweden [email protected] Prof. Dr. I. Endo Prof. Dr. M. Hoare Saitama Industrial Technology Center Department of Biochemical Engineering 3-12-18, Kamiaoki Kawaguchi-shi University College London Saitama, 333-0844, Japan Torrington Place [email protected] London, WC1E 7JE, UK [email protected] Prof. Dr.W.-S. Hu Prof. Dr. G. T. Tsao Chemical Engineering Professor Emeritus and Materials Science Purdue University University of Minnesota West Lafayette, IN 47907, USA 421Washington Avenue SE [email protected] Minneapolis, MN 55455-0132, USA [email protected] [email protected] SOFTbank E-Book Center Tehran, Phone: 66403879,66493070 For Educational Use. www.ebookcenter.ir vi Editorial Board Prof. Dr. B. Mattiasson Prof. Dr. Roland Ulber Department of Biotechnology FB Maschinenbau und Verfahrenstechnik Chemical Center, Lund University Technische Universität Kaiserslautern P.O. Box 124, 221 00 Lund, Sweden Gottlieb-Daimler-Straße [email protected] 67663 Kaiserslautern, Germany [email protected] Prof. Dr. J. Nielsen Prof. Dr. C.Wandrey Center for Process Biotechnology Institute of Biotechnology Technical University of Denmark Forschungszentrum Jülich GmbH Building 223 52425 Jülich, Germany 2800 Lyngby, Denmark [email protected] [email protected] Prof. Dr. G. Stephanopoulos Prof. Dr. J.-J. Zhong Department of Chemical Engineering Bio-Building #3-311 Massachusetts Institute of Technology College of Life Science & Biotechnology Cambridge, MA 02139-4307, USA Key Laboratory of Microbial Metabolism, [email protected] Ministry of Education Shanghai Jiao Tong University 800 Dong-Chuan Road Minhang, Shanghai 200240, China [email protected] Prof. Dr. U. von Stockar Laboratoire de Génie Chimique et Biologique (LGCB) Swiss Federal Institute of Technology Station 6 1015 Lausanne, Switzerland [email protected] Honorary Editors Prof. Dr. A. Fiechter Prof. Dr. K. Schügerl Institute of Biotechnology Institute of Technical Chemistry Eidgenössische Technische Hochschule University of Hannover, Callinstraße 3 ETH-Hönggerberg 30167 Hannover, Germany 8093 Zürich, Switzerland [email protected] [email protected] SOFTbank E-Book Center Tehran, Phone: 66403879,66493070 For Educational Use. www.ebookcenter.ir Advances in Biochemical Engineering/ Biotechnology Also Available Electronically Advances in Biochemical Engineering/Biotechnology is included in Springer’s eBook package Chemistry and Materials Science. If a library does not opt for the whole package the book series may be bought on a subscription basis. Also, all back vol- umes are available electronically. For all customers who have a standing order to the print version of Advances in Biochemical Engineering/Biotechnology, we offer the electronic version via SpringerLink free of charge. If you do not have access, you can still view the table of contents of each volume and the abstract of each article by going to the SpringerLink homepage, clicking on “Chemistry and Materials Science,” under Subject Collection, then “Book Series,” under Content Type and finally by selecting Advances in Biochemical Bioengineering/Biotechnology You will find information about the – Editorial Board – Aims and Scope – Instructions for Authors – Sample Contribution at springer.com using the search function by typing in Advances in Biochemical Engineering/Biotechnology. Color figures are published in full color in the electronic version on SpringerLink. vii SOFTbank E-Book Center Tehran, Phone: 66403879,66493070 For Educational Use. www.ebookcenter.ir viii Advances in Biochemical Engineering/Biotechnology Aims and Scope Advances in Biochemical Engineering/Biotechnology reviews actual trends in modern biotechnology. Its aim is to cover all aspects of this interdisciplinary technology where knowledge, methods and expertise are required for chemistry, biochemistry, micro- biology, genetics, chemical engineering and computer science. Special volumes are dedicated to selected topics which focus on new biotechno- logical products and new processes for their synthesis and purification. They give the state-of-the-art of a topic in a comprehensive way thus being a valuable source for the next 3-5 years. It also discusses new discoveries and applications. In general, special volumes are edited by well known guest editors. The series editor and publisher will however always be pleased to receive suggestions and supplementary information. Manuscripts are accepted in English. In references Advances in Biochemical Engineering/Biotechnology is abbrevi- ated as Adv. Biochem. Engin./Biotechnol. and is cited as a journal. Special volumes are edited
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