Authors: Pallavi Subhraveti Ron Caspi Peter Midford Peter D Karp An online version of this diagram is available at BioCyc.org. Biosynthetic pathways are positioned in the left of the cytoplasm, degradative pathways on the right, and reactions not assigned to any pathway are in the far right of the cytoplasm. Transporters and membrane proteins are shown on the membrane. Ingrid Keseler Periplasmic (where appropriate) and extracellular reactions and proteins may also be shown. Pathways are colored according to their cellular function. Gcf_000010605Cyc: Streptomyces griseus griseus NBRC 13350 Cellular Overview Connections between pathways are omitted for legibility. Anamika Kothari lipid II (meso molybdate phosphate a dipeptide diaminopimelate phosphate phosphate α containing) D-gluconate leu N-acetyl- -D-glucosamine phosphate ethanolamine N,N'-diacetylchitobiose predicted predicted predicted ABC ABC ABC RS08280 RS15505 RS28310 RS07610 RS26715 SecE RS01035 RS23550 RS22715 RS22495 RS21885 RS13085 RS11270 RS05565 RS33195 RS20325 RS20000 RS10485 RS19275 RS32110 RS31955 RS02430 RS02425 FtsW RS31515 RS18000 RS31430 FtsY RS17615 RS09100 RS02210 RS04225 RS04220 RS17370 RS09005 RS09000 RS08995 RS30705 RS04105 RS17170 RS02130 RS30605 RS08820 RS03960 RS30375 RS16775 RS16670 YajC NhaA RS16430 RS29835 RS16140 RS08480 MurJ RS16435 RS08600 SecF RS29040 RS16780 MycP EccE RS04020 LeuE RS02135 RS04110 NgcE RS19510 RS19505 RS28165 RS30975 RS30980 RS09105 RS17655 RS31170 RS17960 RS04500 RS17990 RS02345 YidD RS09520 RS04690 RS02465 RS09710 RS04920 RS10355 RS19885 RS20230 RS10815 Eat RS11380 RS21485 RS11900 RS22585 RS22930 RS24045 RS06875 RS26120 RS27100 RS16915 RS07915 TatA transporter transporter transporter of molybdate of phosphate of a dipeptide lipid II (meso diaminopimelate N-acetyl-α-D-glucosamine phosphate phosphate D-gluconate ethanolamine containing) leu N,N'-diacetylchitobiose phosphate molybdate phosphate a dipeptide

RS03650 Cofactor, Carrier, and Vitamin Biosynthesis C1 Compound Utilization and Assimilation UDP-N-acetyl- undecaprenyl- a methylated UDP-N-acetyl-α-D- α ε a mature UDP-N-acetyl- (4R)-4-hydroxy- a (1->4)- + N ,N -diacetyl-lysyl- a ribonucleoside a D-tyrosyl- an L-cysteinyl- cob(II)yrinate a,c- Fatty Acid and Lipid Biosynthesis Carboxylate Degradation α adenosylcobinamide a purine 2-oxoglutarate nucleobase menadione NADH H α a lipid II leukotriene-D4 α pyridoxal 5'-phosphate biosynthesis II superpathway of coenzyme A biosynthesis I (bacteria) adenosylcobalamin 2-methyladeninyl adenosylcobamide benzimidazolyl adenosylcobamide Fermentation mixed acid fermentation glycolate and formaldehyde formaldehyde -D-glucosamine diphospho-N- muramoyl-L-alanyl- peptidoglycan -D-muramoyl- 2-oxoglutarate Tyr met Cys a protein -D-glucan F0F1 ATP cob(II)yrinate a,c-diamide [2Fe-2S] iron-sulfur biotin biosynthesis from adenosylcobinamide-GDP mycothiol biosynthesis pyruvate decarboxylation to acetyl CoA I pyruvate fermentation to acetate IV D-alanyl-D-alanine (n) diphosphate [tRNA ] [tRNA ] dGDP + + diamide biosynthesis I salvage from cobalamin glyoxylate propanoyl CoA ribonucleoside within DNA γ-D-glutamyl-meso- γ 1,4-alpha- H H RS30410 biosynthesis II (late cluster biosynthesis 8-amino-7-oxononanoate I salvage from cobinamide II biosynthesis from adenosylcobinamide-GDP biosynthesis from adenosylcobinamide-GDP pyruvate fermentation oxidation III oxidation V acetylmuramoyl- D-alanyl-D-alanine (meso-DAP L-alanyl- -D- vitamin B12- amino-acid N- ATP-dependent synthase (early cobalt insertion) degradation I γ 5'-triphosphate vitamin B12- glucan cobalt incorporation) 3-methyl-2- a 5,10- D-glucopyranose palmitate biosynthesis (type II fatty acid synthase) long-chain fatty degradation I a [pyruvate dehydrogenase (mycothiol-dependent) (bacillithiol-dependent) L-alanyl- -D- 2,6-diaminopimelate containing) glutamyl-meso-2,6- dependent acetyltransferase: Clp protease: aldehydo-D-ribose D-glyceraldehyde gln (8S)-8-amino-7- cob(I)alamin octanoyl-[acyl-carrier CDP-diacylglycerol phosphoenolpyruvate pyruvate to acetate II NADH-quinone D-alanyl-D-alanine D-alanyl-D-alanine bifunctional membrane dependent branching uroporphyrinogen-III oxobutanoate methylenetetrahydrofolate cob(II)inamide 6-phosphate 2-methyladenine benzimidazole 6 glutamyl-L-lysyl- alpha- diaminopimeloyl- ribonucleotide D-tyrosyl- SGR_RS20430 peptidyl-tRNA SGR_RS24530 uroporphyrinogen-III L-cysteine desulfurase 5-phosphate 3-phosphate oxononanoate protein] biosynthesis biosynthesis I acid activation glycolate propanoyl-CoA E2 protein] N -lipoyl-L-lysine formaldehyde formaldehyde bifunctional oxidoreductase carboxypeptidase/ carboxypeptidase/ 4-hydroxy-2- dipeptidase: ribonucleotide enzyme: bifunctional adenosylmethionine- pyruvate pyruvate pyruvate D-alanyl-D-alanine ketoglutarate- UDP-N- lytic murein D-alanyl-D-alanine reductase: tRNA(Tyr) hydrolase: SGR_RS24535 citrate RS28890 citrate bifunctional inositol-3- nicotinate-nucleotide-- nicotinate-nucleotide-- an acetoacetyl-[acp] (mitochondria, yeast) a long-chain acyl-CoA 3-oxoadipate UDP-N- adenosylcobinamide subunit NuoK: nuoK D-alanyl-D-alanine- D-alanyl-D-alanine- oxoglutarate SGR_RS22255 bifunctional reductase: glgB uroporphyrinogen-III 3-methyl-2-oxobutanoate -8-amino-7- cob(I)yrinic acid pyruvate kinase: pyk phosphoenolpyruvate pyruvate dehydrogenase pyruvate dependent acetylmuramoyl- transglycosylase: SGR_RS08385 deacylase: SGR_RS07165 clpX α RS09765 uroporphyrinogen-III cysteine pyridoxal 5'- phosphate dimethylbenzimidazole dimethylbenzimidazole DHAP fatty acid carboxylase: citrate degradation degradation acetylglucosamine- kinase/ endopeptidase: dacB endopeptidase: dacB aldolase/2- membrane glutamate N- SGR_RS08385 a (1,6)- -D- C-methyltransferase/ desulfurase: hydroxymethyltransferase: oxononanoate a,c-diamide synthase: cob(II)alamin an acetoacetyl-[acp] long-chain fatty pyruvate kinase: pyk carboxylase: ppc dehydrogenase: (acetyl- dehydrogenase: S-(hydroxymethyl) S-(hydroxymethyl) dioxygenase tripeptide--D- NADH-quinone SGR_RS27580 SGR_RS19720 acetyltransferase/ [+ 2 isozymes] glucosyl-(1,4) C-methyltransferase/ phosphate phosphoribosyltransferase: phosphoribosyltransferase: 3-oxoacyl-[acyl- glycerol-3- glyoxylate SGR_RS09560 -N-acetylmuramyl- adenosylcobinamide- penicillin- D-alanyl-D-alanine penicillin- dehydro-3-deoxy- dipeptidase: ribonucleoside- ATP-dependent uroporphyrinogen- SGR_RS27925 panB transaminase: adenosyltransferase: SGR_RS05410 3-oxoacyl-[acyl- acid--CoA ligase: SGR_RS06670 transferring), SGR_RS06670 an acetyl-holo mycothiol bacillithiol AlkB: alanyl-D- alanine oxidoreductase: nuoN [+ 3 isozymes] amino-acid ribonucleoside- -α-glucan acetate acetate uroporphyrinogen- synthase: superpathway of tetrahydrofolate biosynthesis cob(I)yrinic acid cobT cobT carrier-protein] phosphate SGR_RS09565 acetyl-CoA formate 3-oxoadipate (pentapeptide) phosphate binding carboxypeptidase/ binding phosphogluconate SGR_RS01670 diphosphate Clp protease III synthase: acyl carrier asp SGR_RS31400 SGR_RS10595 carrier-protein] SGR_RS20940 oxaloacetate glyoxylate dihydrolipoyl homodimeric acetyl-CoA [citrate lyase acyl- S-(hydroxymethyl) SGR_RS07515 ligase: murF SGR_RS14705 nuoK acetyltransferase diphosphate RS28290 III synthase: cysteine pdxS pdxT inositol-3- a,c-diamide reductase: fabG dehydrogenase: pyruvate [+ 2 isozymes] citrate 3-oxoadipate- S-(hydroxymethyl) pyrophosphoryl- guanylyltransferase: protein D-alanyl-D-alanine- protein aldolase: eda reductase: proteolytic SGR_RS20650 protein activation (7R,8S)-diaminononanoate cob(I)yrinic acid nicotinate-nucleotide-- nicotinate-nucleotide-- reductase: fabG carboligase: (S)-methylmalonyl- dehydrogenase: type: aceE SGR_RS14720 nuoI Tyr Cys reductase: a metal a metal desulfurase: 2-dehydropantoate phosphate 3-oxoacyl-ACP SGR_RS09430 [+ 10 isozymes] carrier protein] -succinyl-CoA mycothiol mycothiol undecaprenol N- SGR_RS26610 alpha- a mature GlcNAc-1,6- endopeptidase: dacB 2: mrdA SGR_RS11310 D-tyrosine a tRNA ArgJ: argJ cys a tRNA subunit: RS10295 SGR_RS20650 aspartate 1- a,c-diamide adenosyltransferase: dimethylbenzimidazole dimethylbenzimidazole a long-chain malate gcl CoA lpdA phosphate phosphate nuoH SGR_RS14735 2: mrdA SGR_RS11310 cation cation uroporphyrinogen-III SGR_RS09975 synthase: reductase 3-oxoacyl-ACP sn-glycerol [+ 4 isozymes] transferase dehydrogenase: dehydrogenase: acetylglucosamine ketoglutarate- UDP-N-acetyl-α-D- peptidoglycan anhMurNAc- leukotriene-E4 SGR_RS11315 N-acetyl-L- SGR_RS31445 acetate acetate an apo acyl- decarboxylase: GTP ATP-dependent SGR_RS10595 phosphoribosyltransferase: phosphoribosyltransferase: fatty acyl-CoA acetyltransferase: pta acetyltransferase: pta adenosyl- nuoF nuoE (n) penicillin- gly a 2'- SGR_RS11315 C-methyltransferase: uroporphyrinogen-III PLP adenosyltransferase: reductase 3-phosphate dehydrogenase: tartronate methylmalonyl- citrate lyase SGR_RS29055 SGR_RS29055 transferase: dependent γ methionine an S-sulfanyl-[L- carrier protein SGR_RS03725 dethiobiotin SGR_RS18230 cobT cobT FabG: fabG a [pyruvate dehydrogenase a [pyruvate dehydrogenase subunit B: cobinamide muramoyl-L-alanyl- SGR_RS14750 (meso-DAP L-Ala- -D-Glu- binding a N- glyoxylate pyruvate deoxyribonucleoside a peptide RS03465 C-methyltransferase: cobO cob(I)yrinic acid SGR_RS13380 CoA 6 subunit beta: α ε cobA holo-ACP FabG: fabG semialdehyde E2 protein] N - 6 SGR_RS06760 SGR_RS13195 dioxygenase γ-D-glutamyl-meso- N ,N -diacetyl- containing) DAP-D-Ala GDP a metal a metal cobA cysteine desulfurase] GTP synthetase a,c-diamide benzimidazole a (3R)-3- E2 protein] N -S- acetyl phosphate acetyl phosphate S-formylbacillithiol phosphate a purine SGR_RS14755 protein D-ala acetylglucosamine- 5'-diphosphate precorrin-1 synthase: [corrinoid Ins(3)P UDP-N-acetyl- a (3R)-3- 2-hydroxy-3- epimerase: mce dihydrolipoyl-L-lysine SGR_RS27305 3-oxoadipyl-CoA S-formylmycothiol AlkB: 2,6-diaminopimeloyl- lysyl-D-alanine D-ala acetate cation acetatecation precorrin-1 β-alanine cyclohydrolase BioD: bioD adenosyltransferase: adenosylcobinamide- ribotide hydroxybutanoyl-[acp] (R)-lactate (S)-malate acetyldihydrolipoyl-L-lysine undecaprenyldiphospho- ribonucleoside SGR_RS14765 2: mrdA -N-acetylmuramyl- RS20090 SGR_RS13775 (R)-pantoate adenosyltranferase]- α-D-glucosamine 2-methyladenine hydroxybutanoyl-[acp] formate acetyl-CoA oxopropionate (R)-methylmalonyl- pyruvate SGR_RS14400 D-alanyl-D-alanine a holo acyl- I FolE: folE cobO GDP phosphate a 1-acyl-sn acyl-CoA hydrolysis acetate kinase: a citryl-holo muramoylpentapeptide beta-N- 5'-diphosphate (tetrapeptide) RS08290 bifunctional dethiobiotin cob(II)inamide adenosylcobinamide- ribotide phosphate beta-hydroxyacyl- beta-hydroxyacyl- fumarate hydratase: reductase: CoA dehydrogenase: acetate kinase: a metal a metal uroporphyrinogen-III bifunctional carrier protein 7,8- cob(II)alamin- GDP tetrahydrofolate salvage from -glycerol 3- SGR_RS06670 SGR_RS10380 SGR_RS10380 [citrate lyase acyl- acetylglucosaminyltransferase: UDP-N- pyrophosphoryl- pantoate--beta- D-inositol-3-phosphate ACP ACP SGR_RS12220 SGR_RS06460 methylmalonyl- a nucleobase cation cation C-methyltransferase/ uroporphyrinogen-III an S-sulfanyl-[cysteine dihydroneopterin [corrinoid adenosylcobinamide- 5,10-methenyltetrahydrofolate phosphate a 2,3,4-saturated phosphate acetaldehyde citrate synthase/ carrier protein] murGditrans,octacis- UDP formaldehyde succinate NAD + menadiol D-ala acetylmuramoyl- undecaprenol alanine ligase: biotin synthase glycosyltransferase: dehydratase: dehydratase: class II fumarate CoA mutase within DNA uroporphyrinogen- C-methyltransferase/ desulfurase]-[disordered- 3'-triphosphate adenosyltranferase] adenosylcobinamide- GDP 1-acyl-sn-glycerol- fatty acyl CoA acetyltransferase: pta dehydrogenase methylcitrate acetate acetate citrate lyase formate formate undecaprenyldiphospho- L-alanyl-γ-D- RS29485 SGR_RS20395 BioB: bioB [corrinoid mshA a 5,10- SGR_RS16075 SGR_RS16075 acyl-CoA hydratase: D-glycerate small subunit: succinyl-CoA RS21395 III synthase: uroporphyrinogen- form scaffold GDP ribazoletransferase: 3-phosphate (acetylating): synthase: subunit beta: N-acetyl-(N-acetyl-β-D- glutamyl-meso-2,6- adenosyltranferase]- methenyltetrahydrofolate beta-hydroxyacyl- thioesterase: CO H SGR_RS12270 SGR_RS33690 III synthase: protein] complex 1-O-(2-acetamido- SGR_RS26590 bifunctional beta-hydroxyacyl- acyltransferase: 2 2 SGR_RS02680 SGR_RS08265 glycerate kinase: superpathway of acetate SGR_RS27305 glucosaminyl)muramoyl- diaminopimeloyl- SGR_RS20650 [cysteine desulfurase]-S- 9-mercaptodethiobiotin cob(I)inamide ribazoletransferase: ACP SGR_RS22305 acetyl phosphate acetyl-CoA SGR_RS20650 (R)-pantothenate 7,8- 2-deoxy-α-D- SGR_RS26590 methylenetetrahydrofolate ACP SGR_RS26835 citrate synthase: SGR_RS25505 [+ 2 isozymes] utilization and formation L-alanyl-γ-D-glutamyl-L- D-alanine uroporphyrinogen-III sulfanylcysteine:[acceptor cob(I)yrinic acid cob(I)alamin- Coα-[α- dehydratase: [+ 5 isozymes] fumarate oxaloacetate uroporphyrinogen-III dihydroneopterin biotin synthase glucopyranosyl)-1D-myo dehydrogenase/ dehydratase: [+ 7 isozymes] a 2,3,4-saturated SGR_RS24025 glycerate kinase: lysyl-D-alanyl-D-alanine C-methyltransferase: protein]-cysteine a,c-diamide [corrinoid (benzimidazolyl)]-Co SGR_RS16070 a 1,2-diacyl- acetate kinase: acetaldehyde succinyl-CoA C-methyltransferase: type III 3'-phosphate BioB: bioB -inositol 3-phosphate Coα-[α-(2- methenyltetrahydrofolate SGR_RS16070 fatty acid fumarate reductase/ SGR_RS05790 acetate RS14605 cobA sulfurtransferase: adenosyltransferase: adenosyltranferase] β-adenosylcobamide sn-glycerol SGR_RS10380 acetate--CoA RS15785 pantothenate methyladenin-9-yl)]-Co cyclohydrolase: succinate cobA SGR_RS09975 cob(I)yrinic acid a (2E)-but-2-enoyl-[acp] 2-phospho- UDP-N-acetyl- N-acetyl-muramoyl-(L- β β an unstable biotin RS24465 biotin kinase: biotin SGR_RS10595 β-adenosylcobamide 5'-phosphate SGR_RS13395 a (2E)-but-2-enoyl-[acp] 3-phosphate ATP citrate D-gluconate ligase: acs undecaprenyldiphospho- a [2-oxoglutarate dehydrogenase E2 a carboxy- a peptidoglycan an N-acetyl- - a [bis(guanylyl 3-benzyl-3,6 - methyl -D-glucoside a holo [D-alanyl O-phospho- L-malic dCDP precorrin-2 a [cysteine desulfurase]- adeninyl adenosylcobamide biosynthesis 10 dehydrogenase acetate kinase: α hydrogen selenide a uracil in DNA a,c-diamide acetate D-glycerate -D-glucosamine 6 alanyl-γ-D-glutamyl-L- D-ala cys RecA filament- precorrin-2 SGR_RS20410 cob(I)yrinic acid 5'-phosphate an N - phosphatidate biosynthesis degradation N-acetylmuramoyl-L- protein] N -dihydrolipoyl-L-lysine O-acetyl-L-serine adenylated- cys dimer (S. aureus) D-hexosaminide molybdopterin) cys bis(cysteinylglycine) 6-phosphate carrier protein] L-homoserine ATP roseoflavin semialdehyde dADP S-sulfanyl-[disordered- flavin biosynthesis I (bacteria and plants) adenosyltransferase: from adenosylcobinamide-GDP acyl-CoA/acyl-ACP aconitate hydratase flavoprotein: SGR_RS10380 γ vitamin B12- DNA complex precorrin-2 D-erythro-7,8- chorismate a,c-diamide 1-(2-acetamido- formyltetrahydrofolate enoyl-ACP cytidylyltransferase: Degradation/ alanyl- -D-glutamyl-meso 2-oxoglutarate lysyl-D-alanyl-D-alanine) [ThiS sulfur- cofactor - 6-(hydroxymethyl) 5'-phosphate aldehyde DNA form scaffold type I α SGR_RS10595 dehydrogenase: ethanol AcnA: acnA SGR_RS03375 dependent RS24975 dehydrogenase: precorrin-2 C(20)- dihydroneopterin 2-deoxy- -D- α α phosphoribosylglycinamide reductase SGR_RS09120 ADP D-gluconate Utilization/ -2,6-diaminopimeloyl- dehydrogenase, carrier protein] chaperone]- -diketopiperazine dehydrogenase vitamin B12- repair RS29395 protein] complex pantothenate adenosyltransferase: Co -[ - SGR_RS17850 SGR_RS03380 acetyl phosphate acetyl-CoA D-alanyl-D-alanine beta-N- uracil-DNA 6-phospho-beta- ribonucleotide cobA methyltransferase: cysteine aminodeoxychorismate/ cobO glucopyranosyl)- cob(I)yrinic acid adenine formyltransferase: FabI: fabI a CDP- F0F1 ATP gluconokinase: Assimilation - Other D-alanyl-D-alanine E2 component, cysteine synthase: D-alanyl-D-alanine acetylhexosaminidase: L-cysteine cysteine--1-D-myo- cystathionine (NADP(+)): dependent protein RS08100 kinase: dihydroneopterin Coα-[α-(2- (benzimidazolyl)]-Co [+ 7 isozymes] cis-aconitate carboxypeptidase/ glycosylase: glucosidase: reductase: SGR_RS18920 desulfurase: GTP anthranilate synthase menaquinol-9 biosynthesis 1D-myo-inositol a,c-diamide β SGR_RS13415 synthase: succinate SGR_RS29045 acrylonitrile dihydrolipoamide SGR_RS23035 inosityl 2-amino- gamma- bifunctional SGR_RS28055 ribonucleotide RecO: SGR_RS13815 aldolase: folB -adenosylcobamide diacylglycerol D-gluconate carboxypeptidase/ cysteine D-alanyl-D-alanine- SGR_RS22830 membrane SGR_RS31085 SGR_RS24255 SGR_RS08385 sirohydrochlorin SGR_RS27925 component II: adenosylcobinamide N-acetyl-1-D-myo- adenosyltransferase: methyladenin-7-yl)]-Co a butanoyl-[acp] SGR_RS10625 degradation I UDP-N- succinyltransferase: sucB bifunctional o- 2-deoxy-alpha-D- synthase: riboflavin kinase/ aldehyde reductase: recO precorrin-3A β nicotinate-nucleotide-- a butanoyl-[acp] aconitate hydratase Aromatic Compound Degradation D-alanyl-D-alanine- desulfurase: endopeptidase: dacB beta-N- cysteine dipeptidase: a stabilized bifunctional (R)-4'- 6-(hydroxymethyl) SGR_RS18425 inositol-2-amino- cobO -adenosylcobamide a tetrahydrofolate atpD 6-phosphate phosphate acetylglucosamine- acetylhomoserine/ uracil-DNA 6-phospho-beta- FAD synthetase: ribonucleoside- SGR_RS08385 RS25770 cysteine demethylmenaquinol-9 adenosylcobinamide dimethylbenzimidazole AcnA: acnA multifunctional oxoglutarate endopeptidase: dacB SGR_RS09975 penicillin- acetylglucosaminidase desulfurase: SGR_RS22255 glucopyranoside SGR_RS12715 dehydrogenase RecA filament- 3,4-dihydroxy- phosphopantothenate -7,8-dihydropterin 4-amino-4- 2-deoxy-alpha- D- adenosylcob(III) beta-ketoacyl- SGR_RS10635 acetyltransferase: pta -N-acetylmuramyl- o-acetylserine glycosylase: glucosidase: SGR_RS08855 diphosphate RS15735 desulfurase: demethylmenaquinone amidohydrolase: phosphoribosyltransferase: beta-ketoacyl- acrylonitrile decarboxylase/oxoglutarate penicillin-binding cysteine binding domain-containing SGR_RS09975 membrane ligase: (NADP(+)): ribonucleoside- DNA complex 2-butanone- bifunctional 2-amino-4-hydroxy-6- deoxychorismate glucopyranoside alamin-[corrinoid ACP synthase SGR_RS10640 phenylacetate (pentapeptide) sulfhydrylase: SGR_RS32490 SGR_RS05135 reductase: SGR_RS09975 methyltransferase: SGR_RS33210 cobT ACP synthase D-threo-isocitrate cinnamate and 3-hydroxycinnamate dehydrogenase thiamine protein 2: mrdA desulfurase: protein protein: SGR_RS24290 cysteine dipeptidase: SGR_RS29140 SGR_RS07975 diphosphate RS03125 cobalt- an S-sulfanyl-[cysteine 4-phosphate phosphopantothenoylcysteine hydroxymethyldihydropteridine (R)-1-amino- deacetylase: mshB adenosyltranferase] II: fabF SGR_RS10645 degradation I (aerobic) pyrophosphoryl- SGR_RS33225 roseoflavin SGR_RS11310 aminodeoxychorismate SGR_RS14790 II: fabF degradation to 2-hydroxypentadienoate pyrophosphate-binding SGR_RS27925 2: mrdA desulfurase: SGR_RS01670 L-cystathionine (S)-malate reductase: sirohydrochlorin desulfurase]-S- synthase/GTP decarboxylase/ diphosphokinase: folK 2-propanol O cob(I)yrinic acid nicotinate-nucleotide-- SGR_RS10650 undecaprenol N- β-D-glucose adenine SGR_RS11315 precorrin-3B lyase: SGR_RS29920 menaquinol-9 adenosylcobyrate NADP-dependent acrylamide subunit/dihydrolipoyllysine- N-acetyl-muramoyl-(L- an apyrimidinic uracil SGR_RS11310 RS01235 sulfanyl-[disordered- (7,8-dihydropterin- -2-phosphate GlcN-Ins a,c-diamide dimethylbenzimidazole menaquinol-10 biosynthesis a 3-oxohexanoyl-[acp] atpE atpB Fatty Acid and Lipid Degradation coenzyme A phenylacetate acetylglucosamine an N-acetyl-β- SGR_RS27925 MeOH a D-alanyl- cyclohydrolase phosphopantothenate-- a 3-oxohexanoyl-[acp] isocitrate cinnamate residue succinyltransferase γ an alcohol site in DNA 6-phosphate dinucleotide CDP SGR_RS11315 RS01690 17 phosphoribosyltransferase: transferase: acetate alanyl- -D-glutamyl- D-ala a thiocarboxylated- a peptidoglycan D-hexosamine 3-benzyl-3,6 - [D-alanyl precorrin-3B (C )- form scaffold II: SGR_RS30430 cysteine ligase CoaBC: coaBC 6-yl)methyl 4-aminobenzoate adenosyltransferase: all-trans- dehydrogenase: amidase: subunit: SGR_RS10945 L-selenocysteine ADP 2,5-diamino-6- cysteine--1-D-myo- cobT 3-oxoacyl-[acyl- ATP oleate β-oxidation SGR_RS13195 L-lysyl-D-alanine) ala [ThiS sulfur- with D,D cross- D-ala a [bis(guanylyl bis(cysteinyl)- 6- gly carrier protein] methyltransferase: protein] complex (R)-4'- diphosphate SGR_RS10595 1,4-dihydroxy- 3-oxoacyl-[acyl- glyoxylate cycle SGR_RS05970 β SGR_RS06590 phenylacetate-- a [2-oxoglutarate dehydrogenase E2 AMP [cysteine desulfurase]-S- (5-phospho-D- inosityl 2-amino- decaprenyl carrier-protein] fatty acid -oxidation I (generic) carrier protein] link (S. aureus) ala molybdopterin) (hydroxymethyl) cobalt-factor III SGR_RS18920 phosphopantothenoyl- cob(I)yrinic acid 2-naphthoate carrier-protein] [+ 3 isozymes] CoA ligase: paaF bifunctional 3- undecaprenyldiphospho- protein] N 6 -S-succinyldihydrolipoyl-L-lysine TatA sulfanylcysteine:[acceptor ribosylamino) dihydropteroate adenosyl- 2-deoxy-alpha-D- adenine ribotide diphosphate reductase: fabG 2-oxoglutarate cofactor -diketopiperazine RS02610 L-cysteine a,c-diamide reductase: fabG oleate phenylpropionate/ muramoylpentapeptide beta-N- precorrin-4 protein]-cysteine pyrimidin- synthase: folP cobinamide glucopyranoside adenosylcobinamide- phosphate 3-oxoacyl-ACP succinate acetyl-CoA a (3Z)-alk-3- acrylate chaperone]-S- bifunctional NAD de novo biosynthesis adenosyltransferase: cinnamic acid acetylglucosaminyltransferase: RS07890 sulfurtransferase: 4(3H)-one phosphate ligase: GDP 5-methylbenzimidazolyl adenosylcobamide reductase 3-oxoacyl-ACP enoyl-CoA phenylacetyl-CoA 3-hydroxycinnamate sulfanyl-L-cysteine precorrin-4 C(11)- phosphopantothenoylcysteine dihydropteroate II (from tryptophan) cobO reductase glyoxylate long-chain fatty dioxygenase murG a [cysteine SGR_RS09975 bifunctional SGR_RS29140 biosynthesis from adenosylcobinamide-GDP FabG: fabG methyltransferase: decarboxylase/ synthase: folP bifunctional FabG: fabG malate synthase acid--CoA ligase: 2-phenylacetyl- ferredoxin subunit: desulfurase]-(S- diaminohydroxyphosphoribosylaminopyrimidine adenosylcobinamide- lipid II (meso cobalt-precorrin-3 cobM phosphopantothenate-- adenosylcobinamide trp deacetylmycothiol adenosylcobalamin DMKH2-10 a (3R)-3- A: SGR_RS06340 SGR_RS17830 CoA SGR_RS27915 UDP RS28745 sulfanyl) -[disordered- deaminase/5-amino-6-(5-phosphoribosylamino) 7,8- kinase/ GDP 5-methylbenzimidazole a (3R)-3- isocitrate lyase: aceA Respiration diaminopimelate RS14865 2 cysteine ligase CoaBC: coaBC tryptophan 2,3- hydroxyhexanoyl-[acp] malate synthase [+ 10 isozymes] a (2E)-2- epoxidase: form scaffold uracil reductase RibD: ribD mycothiol ribazoletransferase: demethylmenaquinone hydroxyhexanoyl-[acp] (2E)-3-(5,6- containing) RS14870 precorrin-5 dihydropteroate adenosylcobinamide- dioxygenase: A: SGR_RS08040 enoyl-CoA paaJ paaC chlorpyrifos degradation protein] complex 5-amino-6-(5- 4'-phosphopantetheine superpathway of thiamine diphosphate biosynthesis II synthase: SGR_RS26590 nicotinate-nucleotide-- methyltransferase: beta-hydroxyacyl- oleoyl-CoA dihydroxycyclohexa-1,3- bifunctional phosphate SGR_RS16905 beta-hydroxyacyl- 2-oxoisovalerate decarboxylation enoyl-CoA precorrin- phospho-D- N-Formyl-L- dimethylbenzimidazole SGR_RS14790 ACP a 2,3,4-saturated acyl-CoA/acyl-ACP paaB paaA dien-1-yl)prop-2-enoate folylpolyglutamate guanylyltransferase: mshD adenosylcobinamide-GDP α α ACP long-chain fatty a peptidoglycan dimer (meso γ a DNA containing an sn-glycero-3- a peptide with β-D-glucose (3R,5S)-3- 6A synthase ribosylamino)uracil D-ribulose pantetheine- kynurenine Co -[ -(adenin-9-yl)]- phosphoribosyltransferase: dehydratase: to isobutanoyl-CoA acyl-CoA/acyl-ACP hydratase: 2-(1,2-epoxy-1,2- 5-methoxy-6- L-alanyl- -D-glutamyl-L- chitin a [DNA]-3'- a 5'-phospho- phosphoenol RS28785 cobalt-precorrin-4 SGR_RS26610 β fatty acid acid--CoA ligase:dehydrogenase: a 2,3,4- chlorpyrifos 5-methoxybenzimidazole NaMN NaMN an apurinic/ KDGP phospho-N-(acyl) a [glutamine- O-ureido-L- bifunctional phosphate synthase/ cys mycothiol salvage from cobinamide I pyridoxal 5'-phosphate biosynthesis I Co -adenosylcobamide cobT menaquinol-10 SGR_RS16075 dehydratase: an [apo BCAA dehydrogenase: SGR_RS05945 dihydrophenyl) methylbenzimidazole -diaminopimelate containing) lysyl-D-alanyl-D-alanine ATP asp hydroxyl [DNA] dGDP pyruvate ala UDP-N-acetyl- an N-terminal glu ala 6-phosphate ATP hydroxy-1- (deacetylating): 5-phosphate kynurenine SGR_RS20940SGR_RS18500 saturated (3R)-3- phosphotriesterase: apyrimidinic site ethanolamine synthetase]- homoserine α inositol-3- RS27890 cobalt precorrin- a [cysteine desulfurase]- diaminohydroxyphosphoribosylaminopyrimidine adenylyltransferase: dihydrofolate adenosylcobinamide- 5'-phosphate SGR_RS16075 D-threo-isocitrate (S)-malate dehydrogenase SGR_RS17850 acetyl-CoA -D-muramate L-methionine biotin pyrroline-5- RS27950 SGR_RS05920 bifunctional formamidase: cob(II)inamide D-erythrose nicotinate-nucleotide-- beta-hydroxyacyl- alpha-ketoacid [+ 10 isozymes][+ 10 isozymes] a 2,3,4- hydroxyacyl-CoA SGR_RS34465 L-tyrosine phosphate 11 [scaffold protein- synthase: cysteine GDP beta-hydroxyacyl- 6 a 2,3,4-saturated carboxylatepyrroline-5- 4 (C )- deaminase/5-amino-6-(5-phosphoribosylamino) coaD a [ThiS sulfur- SGR_RS16895 dimethylbenzimidazole ACP E2 protein] N [+ 10 isozymes] saturated (3S)-3- nicotinate-nucleotide-- nicotinate-nucleotide-- D-alanyl-D-alanine D-alanyl-D-alanine beta-N- non- precorrin-6A (2Fe-2S)] complex 3,4-dihydroxy- SGR_RS24555 desulfurase: cob(I)yrinic acid 4-phosphate ACP dehydrogenase fatty acyl CoA 2,3-dihydroxy-trans-cinnamate diethylthiophosphate endonuclease bifunctional argininosuccinate type I methionyl glutamate-- synthase: carboxylate methyltransferase: uracil reductase RibD: ribD 3'-dephospho- carrier protein] phosphoribosyltransferase: dehydratase: -lipoyl-L-lysine (2E,9Z)- hydroxyacyl-CoA dimethylbenzimidazole dimethylbenzimidazole carboxypeptidase/ carboxypeptidase/ glycerophosphoryl acetylhexosaminidase: homologous UDP-N- 5-amino-6-(5- 2-butanone- SGR_RS27925 a,c-diamide dehydratase: subunit beta: III: nth 4-hydroxy-2- bifunctional [glutamine synthase: argG pyruvate aminopeptidase: cysteine ligase: SGR_RS05410 biotin-- reductase: RS28980 cobM CoA 7,8-dihydrofolate L-kynurenine Coα-[α-(adenin-7-yl)]- cobT SGR_RS16070 aconitate hydratase malate dehydrogenase: octadecenoyl-CoA 3-hydroxyacyl-CoA phosphoribosyltransferase: phosphoribosyltransferase: D-alanyl-D-alanine- D-alanyl-D-alanine- diester SGR_RS22830 end-joining acetylmuramate-- phospho-D- 4-phosphate adenosyltransferase: menaquinol-11 biosynthesis SGR_RS16070 SGR_RS18565 2-oxepin-2(3H)- oxoglutarate synthetase] kinase: pyk map SGR_RS30760 inositol-3- [acetyl-CoA- proC cobalt- monoglutamate cysteine Coβ-adenosylcobamide AcnA: acnA SGR_RS13380 enoyl-CoA dehydrogenase: cobT cobT endopeptidase: dacB endopeptidase: dacB bifunctional DNA- phosphodiesterase: beta-N- argininosuccinate DNA L-alanine ligase: ribitylamino)uracil synthase/GTP dephospho- SGR_RS10595 adenosylcobinamide- 5-methylbenzimidazole alpha-ketoacid ylideneacetyl-CoA aldolase/2- adenylyltransferase/ pyruvate phosphate carboxylase] Hyp RS27640 precorrin-5A a [co-chaperone]- desulfurase: kynurenine 3- 4-phospho- all-trans- a (2E)-hex-2-enoyl-[acp] hydratase: coenzyme A SGR_RS06765 penicillin-binding formamidopyrimidine SGR_RS24450 acetylglucosaminidase synthase: ligase: ligD SGR_RS07120 [+ 2 isozymes] [+ 2 isozymes] RS07475 cyclohydrolase CoA kinase: a carboxy- cob(I)yrinic acid GDP ribotide phosphate a (2E)-hex-2-enoyl-[acp] dehydrogenase (2Z,4E,7E)-2-hydroxy- nicotinate-nucleotide-- nicotinate-nucleotide-- penicillin-binding dehydro-3-deoxy- [glutamine synthetase]- kinase: pyk synthase: ligase: [scaffold protein- SGR_RS09975 monooxygenase: D-erythronate undecaprenyl 1,4-dihydroxy- SGR_RS05945 protein 2: mrdA glycosylase/ [+ 6 isozymes] domain-containing SGR_RS29770 precorrin-6B II: SGR_RS30430 SGR_RS27615 adenylated- an [L-cysteine a,c-diamide subunit beta: a 2,3,4-saturated a 2,3,4-saturated 6-oxonona-2,4,7- diethylphosphate dimethylbenzimidazole dimethylbenzimidazole protein 2: mrdA phosphogluconate adenylyl-L-tyrosine [+ 3 isozymes] SGR_RS18230 SGR_RS12895 RS01740 (2Fe-2S)] complex SGR_RS04345 diphosphate 2-naphthoate enoyl-ACP acetyl-CoA C- DNA-(apurinic protein: SGR_RS24290 UDP-N-acetyl- γ 1-deoxy-L- acyl-CoA/acyl-ACP cis-aconitate oxaloacetate dihydrolipoyl SGR_RS18650 (S)-3-hydroxy-(9Z) fatty acyl CoA 3-oxoacyl-CoA phosphoribosyltransferase: phosphoribosyltransferase: aldolase: eda phosphorylase: -L-glutamyl- precorrin-6y C5,15- coenzyme A a 7,8-dihydrofolate [ThiS sulfur- desulfurase]-S- adenosyltransferase: adenosylcobinamide- reductase acyltransferase: 3-oxo-5,6- triene-1,9-dioate or apyrimidinic α-D-muramoyl- met a peptide Ins(3)P glycero-tetrulose 3-hydroxy- dehydrogenase: dehydrogenase: -octadecenoyl-CoA cobT cobT a peptidoglycan with γ sn-glycerol an N- SGR_RS26295 pyruvate D-alanine cobalt- ARP carrier protein] sulfanyl-L-cysteine [corrinoid cobO GDP FabI: fabI an [apo BCAA an [apo BCAA dehydrogenase didehydrosuberyl- L-alanyl- -D-glutamyl- site) lyase: mutM canavaninosuccinate L-alanine biotinyl-5'- RS02555 methyltransferase 4-phosphate L-kynurenine (3R)-3-hydroxy-2-oxo- SGR_RS17850 aconitate hydratase lpdA 3-hydroxyacyl-CoA SGR_RS07225 D,D cross-links (meso- D-ala D-ala 3-phosphate acylethanolamine N-acetyl-D- [DNA] dGTP precorrin-5B dihydrofolate adenosyltranferase]- ribazoletransferase: dehydrogenase E2 protein] N 6 -S-[2- CoA semialdehyde L-lysyl-D-alanine D-glyceraldehyde chitin adenylate (decarboxylating) a [chaperone-ATP]- D-glyceraldehyde 4 phosphooxybutanoate D-glyceraldehyde AcnA: acnA dehydrogenase: phospholipases 5-methoxy-6- diaminopimelate containing) pyruvate glucosamine RS27040 cobalt-precorrin- reductase: cysteine kynureninase: cob(II)inamide pyruvate bis(guanylyl molybdopterin) SGR_RS26590 a hexanoyl-[acp] [+ 7 isozymes] citrate synthase/ E2 protein] N 6 - methylpropanoyl]dihydrolipoyl- 3-phosphate a [glutamine subunit CbiE: cbiE 6,7-dimethyl-8- 3-phosphate 3-phosphate 5-methoxybenzimidazole nicotinate nicotinate 5B (C(1))- [co-chaperone]- SGR_RS20710 desulfurase: kynU phosphoserine cofactor sulfurylation DMKH2-11 methylcitrate synthase: dihydrolipoyl-L-lysine L-lysine SGR_RS06765 a 1,2-diacyl- (2Z)-2-hydroxypenta- methylbenzimidazole a 3'-terminal a 5'-phospho- synthetase]-O [scaffold protein- ribityllumazine α α a hexanoyl-[acp] fumarate methyl parathion degradation ribotide phosphate ribotide phosphate unsaturated sugar [DNA] methyltransferase: precorrin-7 1-deoxy-D- SGR_RS27925 NAD de novo biosynthesis transaminase: Co -[ -(5- beta-ketoacyl- SGR_RS08265 3-oxo-(9Z)- a phosphatidylcholine sn-glycerol 2,4-dienoate 4 -(5'-adenylyl) (2Fe-2S)] complex synthase: thiamine diphosphate salvage II a tetrahydrofolate gly 1-deoxy-D- demethylmenaquinone 3-oxo-5,6- SGR_RS18910 xylulose-5- cysteine I (from aspartate) 3-hydroxyanthranilate serC cys methylbenzimidazolyl)]- ACP synthase citrate synthase: octadecenoyl-CoA 3-phosphate -L-tyrosine MscL SGR_RS30435 [corrinoid β methyltransferase: beta-ketoacyl- acetyl-CoA didehydrosuberyl- precorrin-6y C5,15- phosphate desulfurase: 4-phosphooxy- xylulose-5- Co -adenosylcobamide II: fabF acetyl-CoA C- methyl parathion cobalt- 4-amino-2-methyl-5- glycine adenosyltranferase]- SGR_RS14790 ACP synthase SGR_RS24025 CoA methyltransferase synthase: SGR_RS09975 L-threonine phosphate cysteine 5'-phosphate citrate acetyl-CoA acyltransferase: a 1-acyl-sn HtpX precorrin-6A (decarboxylating) 6,7-dimethyl-8-(1- pyrimidinemethanol oxidase asp cob(I)inamide synthase: a 3-oxooctanoyl-[acp] II: fabF 2-oxo acid a peptidoglycan sn-glycero-3- a [glutamine UDP-N-acetyl- (1E,4S,5E,7R)- DNA combined UDP a reduced SGR_RS07310 a phosphatidylcholine -glycero-3- L-threo-3- phosphoenol an L-asparaginyl- 34 cobalt-precorrin- D-ribityl)lumazine ThiO: thiO L-aspartate cob(I)yrinic acid desulfurase: menaquinol-11 dehydrogenase SGR_RS07225 phosphotriesterase: 5-hydroxybenzimidazole NaMN meso-diaminopimelate UDP-N-acetyl-α-D-muramoyl- dimer (E. faeciums) 2,3- a holo-[DhbB aryl- a ferrocytochrome stearoyl-CoA phospho-N- oxaloacetate synthetase]-O α D-glt a RNA-DNA hybrid germacra-1(10) with exogenous a cytidine lys subunit CbiE: cbiE a [chaperone- bifunctional 1-deoxy-D- a thiocarboxylated- 2-amino-3- SGR_RS07310 phosphocholine ITP -D-muramoyl- dADP pyruvate Asn factor 420 an [2Fe-2S] SGR_RS27925 carrier protein] b 4 phenylserine [tRNA ] Ile2 vitamin B12- 6A reductase: ADP]-[disordered- oxidase: a,c-diamide 3-oxoacyl-[acyl- a 3-oxooctanoyl-[acp] subunit E2: SGR_RS34465 L-alanyl-D-glutamate dihydroxybenzoate 5 (arachidonoyl) -(5'-adenylyl) L-alanine ,5-dien-11-ol DNA to form a in tRNA NADPH- RS26085 riboflavin hydroxymethylpyrimidine xylulose 5- 2-iminoacetate [ThiS sulfur- carboxymuconate- Coα-[α-(5- (7Z)-hexadecenoyl-CoA trans-2,3- parathion degradation dependent SGR_RS18915 precorrin-8x cluster protein form scaffold SGR_RS20400 adenosyltransferase: 3-amino-1- 1-deoxy-D- cysteine carrier-protein] SGR_RS18570 ethanolamine -L-tyrosine recombinational dependent synthase: kinase/ phosphate carrier protein] 6-semialdehyde methylbenzimidazolyl)]- a 2-acyl-sn dehydroadipyl-coA D-alanyl-D-alanine Holliday 2-iminosuccinate SGR_RS10595 hydroxyacetone xylulose 5- desulfurase: 3-oxoacyl-[acyl- Macromolecule Modification tRNA processing acyl-CoA/acyl-ACP nicotinate-nucleotide-- bifunctional junction ribonucleotide F420 cobalt- protein] complex SGR_RS30420 phosphomethylpyrimidine β reductase: fabG 2-oxo acid a phosphatidylcholine -glycero-3- UDP-N-acetylmuramoyl- carboxypeptidase/ (2,3- acyl-CoA UDP-N- low specificity germacradienol/ peptidyl-tRNA junction tRNA a sugar RS33005 a sugar precorrin-8X SGR_RS09975 Co -adenosylcobamide carrier-protein] dehydrogenase: enoyl-CoA parathion dimethylthiophosphate 4-nitrophenol dimethylbenzimidazole RNase H/acid reductase: precorrin-6B kinase: thiD thiazole cob(I)yrinic acid 1-phosphate phosphate factor 420 3-oxoacyl-ACP dehydrogenase phosphocholine L-alanyl-D-glutamate-- D-alanyl-D-alanine- dihydroxybenzoyl) desaturase: glycerophosphodiester phosphoenolpyruvate bifunctional [glutamine acetylmuramoyl- L-threonine pyruvate geosmin hydrolase: resolvase lysidine(34) reductase: methylmutase: riboflavin AIR quinolinate an [L-cysteine reductase: fabG SGR_RS17850 hydratase: phosphoribosyltransferase: phosphatase: SGR_RS08385 cobalt-precorrin- synthase: a,c-diamide polyglutamylation reductase a polycistronic subunit E2: 2, 6-diaminopimelate endopeptidase: dacB adenylate synthase: SGR_RS01625 phosphodiesterase: carboxykinase (GTP) synthetase] L-alanine--D- aldolase: kinase: pyk synthase: SGR_RS07165 RuvX: ruvX synthetase npdG SGR_RS18925 synthase desulfurase]-S- 3-oxoacyl-ACP SGR_RS05945 cobT SGR_RS26005 resolution of ribonucleoside- an oxidized RS25575 15 HMP-P SGR_RS26890 adenosyltransferase: FabG: fabG tRNA precursor SGR_RS18655 [+ 10 isozymes] phosphotriesterase: : SGR_RS12600 SGR_RS32570 pyruvate SGR_RS34160 TilS: tilS 6B (C )- an [Fe-S cluster bifunctional phosphomethylpyrimidine NadA: nadA quinolinate sulfanyl-L-cysteine reductase phospholipase C, (3S)- ligase: SGR_RS00835 penicillin-binding SGR_RS33620 acyl-CoA SGR_RS17900 adenylyltransferase/ glutamate ligase: [+ 2 isozymes] [+ 2 isozymes] recombinational[+ 3 isozymes] factor 420 a sugar RS04040 a sugar hydrogenobyrinate cobO oxidized (2E,7Z)- SGR_RS34465 nicotinate-nucleotide-- kinase: pyk diphosphate methyltransferase biosynthesis riboflavin kinase/ 5-(2-hydroxyethyl) bifunctional synthase ThiC: thiC cysteine a (3R)-3- FabG: fabG phosphocholine- hydroxyadipyl- UDP-N-acetylmuramoyl- protein 2: mrdA desaturase: [+ 6 isozymes] [glutamine synthetase]- SGR_RS27025 junction 2-[(2R,5Z)- quinolinate carboxylating pyridoxine factor 420-0 hexadecenoyl-CoA dimethylbenzimidazole reductase: [decarboxylating]: chaperone]-ATP FAD synthetase: -4-methylthiazole hydroxymethylpyrimidine desulfurase: coenzyme F420- specific: CoA L-alanyl-D-glutamate-- a 2,3- SGR_RS01955 adenylyl-L-tyrosine formation of two a lysidine 34 hydrogenobyrinate HMP-P 2-carboxy-4- nicotinate- adenosylcobinamide hydroxyoctanoyl-[acp] a (3R)-3- paraoxon degradation phosphoribosyltransferase: phosphoenolpyruvate benzaldehyde acetone (-)-geosmin SGR_RS11310 SGR_RS17475 5'-phosphate SGR_RS27925 0:L-glutamate enoyl-CoA 3-hydroxyacyl-CoA phosphorylase: a nucleoside 5'- gly Asn Ile2 a,c-diamide synthase: SGR_RS08855 kinase/ methylthiazol-5(2H carboxylating SGR_RS04285 diethylthiophosphate 4-nitrophenol cobT 2, 6-diaminopimelate a peptidoglycan tetramer dihydroxybenzoyl- IDP UDP-N-acetyl- DNA asn tRNA intact strands in tRNA SGR_RS11315 nucleotide bis(guanylyl ligase: beta-hydroxyacyl- hydroxyoctanoyl-[acp] a tRNA precursor hydratase: dehydrogenase: anandamide sn-glycerol SGR_RS26295 α monophosphate pyruvate predicted RS12800 SGR_RS28135 phosphomethylpyrimidine nicotinate- bifunctional pyridoxal 5'- cysteine ribonuclease D: ligase: SGR_RS27010 with a D,D cross-link D-ala [DhbB aryl- -D-muramoyl-L- dATP cobalt-precorrin-7 FMN bifunctional )-ylidene]ethyl diphosphorylase: molybdopterin) folate transformations III (E. coli) SGR_RS22360 ACP with a 5' extension SGR_RS05945 phospholipase C, SGR_RS06765 a ferricytochrome oleoyl-CoA 3-phosphate dUDP ABC kinase: thiD nucleotide adenosylcobinamide phosphate desulfurase: oxidized beta-hydroxyacyl- SGR_RS07220 paraoxon (Enterococcus faecium) carrier protein] alanyl-D-glutamate a sugar a sugar hydrogenobyrinate 4-methyl-5-(2- hydroxymethylpyrimidine phosphate SGR_RS20405 cofactor dehydratase: and a long 3' trailer phosphocholine- b transporter adenosylcobalamin biosynthesis kinase/ synthase: SGR_RS09975 ACP a tRNA precursor with (S)-3-hydroxy-(7Z) 5-hydroxybenzimidazole α 5 a [glutamine- bifunctional cobalt- a,c-diamide bifunctional phosphooxyethyl) kinase/ diphosphorylase: factor 420-1 SGR_RS16075 specific: 3-oxoadipyl-CoA nicotinate UDP-N-acetyl- -D-muramoyl-L-alanyl- of a sugar from adenosylcobinamide-GDP I HMP-PP a [bis(guanylyl dehydratase: a 5' extension and -hexadecenoyl-CoA ribotide phosphate γ ADP synthetase]- precorrin-7 (C(5))- riboflavin kinase/ thiazole molybdopterin biosynthesis phosphomethylpyrimidine SGR_RS20405 NaMN adenosylcobinamide- SGR_RS14965 a tetrahydrofolate F420-1:γ- SGR_RS09900 phosphotriesterase: -D-glutamyl-meso-2,6-diaminopimelate putative molybdopterin) beta-hydroxyacyl- SGR_RS16075 a short 3' extension a 1,2-diacyl- L-tyrosine methyltransferase/ FAD synthetase: kinase: thiD phosphate pyridoxamine glutamyl ligase: 3-hydroxyacyl-CoA a phosphatidylcholine diethylphosphate SGR_RS34465 RS14405 cobaltochelatase: 2-(2-carboxy-4- [bis-MGD cofactor ACP ribonuclease sn-glycerol predicted cobalt-precorrin- 5,6-dimethylbenzimidazole SGR_RS08855 thiamine NaMN nicotinate-nucleotide guanylyltransferase: 5'-phosphate cofactor methionine SGR_RS22360 beta-hydroxyacyl- dehydrogenase: SGR_RS28145 methylthiazol-5- adenylyltransferase: chaperone]- chaperone]-S- dehydratase: ribonuclease D: P protein ABC 6B (C(15))- phosphate ATP cys HMP-PP SGR_RS26610 oxidase: pdxH synthase: metH ACP ribonuclease D: SGR_RS06765 di-trans,octa-cis UDP-N-acetyl- a mature peptidoglycan an N-formyl-L- a 2'- N-acetyl-β-D- an N-terminal- a glucosylated a sugar a sugar cobaltochelatase nicotinate-nucleotide-- FAD yl)ethyl phosphate nicotinate-nucleotide SGR_RS24750 bis-MGD sulfanyl-L-cysteine oxidized SGR_RS16070 SGR_RS07220 component: a 1-phosphatidyl- diethylphosphate 4-nitrophenol sn-glycerol a CDP- a holo-[EntB aryl- sn-glycero-3- hydrogen a reduced O-succinyl-L- pyridoxamine an L-cysteinyl- transporter methyltransferase: synthase: dehydratase: SGR_RS07220 3-oxo-(7Z)- a 1,2-diacyl- succinyl-CoA -undecaprenyl α-D-muramoyl- (meso-diaminopimelate 2,3- methionylaminoacyl- deoxyribonucleoside glucosaminyl-(1 L-allo-threonine L-methionyl-L- urea-1-carboxylate a glycyl-[tRNA Ala ] NADH glycogenin subunit CobN: cobN dimethylbenzimidazole adenylyltransferase: adenosyl-cobinamide methionine synthase: factor 420-2 rnpA 1D-myo-inositol 3-phosphate diacylglycerol [DNA] phosphoethanolamine peroxide 5'-phosphate [tRNA Pro ] of a sugar SGR_RS17475 cysteine nicotinate adenine PLP SGR_RS16070 hexadecenoyl-CoA sn-glycerol γ carrier protein] thioredoxin homoserine 1,4-alpha- phosphoribosyltransferase: SGR_RS26920 molybdopterin- thiamine SGR_RS24750 phosphate dihydrofolate SGR_RS09940 a (2E)-oct-2-enoyl-[acp] ribonuclease 4,5-bisphosphate fatty acid β-oxidation II (plant peroxisome) phosphatephospho-N- L-alanyl- -D- containing) dihydroxybenzoate tRNA 5'-triphosphate -> 4)-N-acetyl- alanyl-[protein] pyridoxal 5'- cob(II)yrinate synthase desulfurase: dinucleotide reductase: a tRNA precursor with acetyl-CoA C- acetylmuramoyl- β glucan RS24030 cobT phosphate nicotinate adenine serine PH: rph glutamyl-meso-2,6- -D-muramate phosphate predicted cobalt-precorrin-8 a,c-diamide adenylyltransferase: SGR_RS27925 bifunctional SGR_RS20710 a (2E)-oct-2-enoyl-[acp] a short 3' extension acyltransferase: pentapeptide- glycerophosphoryl thioredoxin- allophanate NAD(+) branching thiamine synthase: dinucleotide NAD+ synthase: sulfo-bis(guanylyl hydroxymethyltransferase: enoyl-ACP polyribonucleotide diaminopimeloyl- lytic murein CDP-diacylglycerol-- (2,3- peptide DNA polymerase cystathionine low specificity type I methionyl D-tyrosyl- synthase: Cys- ABC nicotinate-nucleotide-- moeZ cysteine GTP thiamine diphosphate adenosylcobinamide a 7,8-dihydrofolate a 5-methyltetrahydrofolate SGR_RS07225 a (2E)-2-enoyl-CoA transferase: diester dependent hydrolase diphosphatase: enzyme: a sugar a sugar phosphate SGR_RS26920 SGR_RS26225 molybdopterin) SGR_RS10065 reductase a tRNA precursor nucleotidyltransferase: D-alanyl-D-alanine transglycosylase: glycerol-3-phosphate 3- dihydroxybenzoyl) deformylase: III subunit beta-N- gamma- L-threonine aminopeptidase: tRNA(Tyr) SGR_RS14965 tRNA(Pro) transporter dimethylbenzimidazole a carboxy- desulfurase: biosynthesis I (E. coli) NAD+ synthase: NAD+ synthase: kinase/ glycine cleavage system acyl-CoA/acyl-ACP SGR_RS27020 phosphodiesterase: thiol subunit 1: nudC glgB cofactor FabI: fabI with a 5' extension SGR_RS08740 long-chain fatty SGR_RS27580 phosphatidyltransferase: adenylate synthase: def gamma and tau: acetylhexosaminidase: synthase: aldolase: map deacylase: pyridoxamine deacylase: of a sugar phosphoribosyltransferase: thiamine- adenylated SGR_RS26225 SGR_RS26225 + adenosylcobinamide- [+ 2 isozymes] aminomethyltransferase dehydrogenase: (5Z)-tetradecenoyl-CoA SGR_RS24450 SGR_RS15795 SGR_RS09975 GTP 3',8- 2-[(2R,5Z)- NAD heme a biosynthesis ribonuclease ribonuclease D: acid--CoA ligase: acyl-CoA pgsA SGR_RS19085 peroxidase: SGR_RS12715 SGR_RS32570 SGR_RS19720 ybaK a glycogen RS23165 cobT phosphate [small subunit of an [L-cysteine thiamine phosphate GcvT: gcvT a (6S)-5-formyltetrahydrofolate SGR_RS17850 [+ 3 isozymes] SGR_RS33620 peptide SGR_RS22830 [+ 2 isozymes] reduced β- 5'-phosphate NAD salvage pathway I (PNC VI cycle) cyclase 2-carboxy-4- an octanoyl-[acp] PH: rph SGR_RS07220 a 2,3,4-saturated SGR_RS20940 oxidase: enoyl-CoA [+ 6 isozymes] bcp predicted cobyrinate kinase: molybdopterin desulfurase]-S- phosphate NAD + guanylyltransferase: acyl-CoA/acyl-ACP deformylase: [+ 17 isozymes] beta-N- nicotinamide D- oxidase: pdxH adenosylcobinamide- α-ribazole MoaA: methylthiazol-5(2H dipyrromethane [+ 7 isozymes] ribonuclease SGR_RS33175 hydratase: 1-(3-sn- AMP SGR_RS09410 synthase] sulfanyl-L-cysteine SGR_RS26610 protoheme 5-formyltetrahydrofolate dehydrogenase: fatty acid [+ 10 isozymes] a mature peptidoglycan a mature peptidoglycan CMP a 2,3- def acetylglucosaminidase ammonium CO ribonucleotide PLP ABC 5'-phosphate moaA thiamine- )-ylidene]ethyl cofactor biosynthesis beta-ketoacyl- P protein SGR_RS05945 an N-terminal L- 2 a sugar a sugar cobyrinate GDP + HMP-PP phosphatidyl) succinate acetaldehyde Ala Pro transporter NAD (8S)-3',8-cyclo-7,8- phosphate protoheme IX molybdenum cofactor biosynthesis methylenetetrahydrofolatecyclo-ligase: an octanoyl-[acp] SGR_RS18500 acyl-CoA undecaprenyldiphospho- UMP with (L-alanyl-γ-D- strand (non- dihydroxybenzoyl- ethanolamine sn-glycerol domain-containing an oxidized H O L-homocysteine gly met a tRNA gly cys a tRNA A,C-diamide thiamine phosphate adenosylcobinamide- methylenetetrahydrofolate ACP synthase component: -sn-glycerol [DNA] 2 alanyl-[protein] of a sugar molybdopterin dihydroguanosine kinase: di-trans,poly-cis an apo-[hydroxymethylbilane farnesyltransferase: dehydrogenase: SGR_RS21340 [+ 10 isozymes] a 2,3,4-saturatedoxidase: a 2,3,4-saturated (3S N-acetylmuramoyl-L- glutamyl-meso-2,6- reducing terminus) [EntB aryl- 3-phosphate protein: SGR_RS24290 thioredoxin synthase: adenosylcobinamide- diphosphate GDP reductase [NAD(P)H]: metF II: fabF rnpA 3-phosphate a L-methionylaminoacyl- RS13525 NAD(+) synthase 5'-triphosphate SGR_RS09410 -undecaprenyl synthase]-L-cysteine SGR_RS27875 SGR_RS13395 (2E,5Z)- fatty acyl CoASGR_RS00660 )-3-hydroxyacyl-CoA alanyl-γ-D-glutamyl-meso diaminopimeloyl-D- carrier protein] formate SGR_RS28135 GDP NAD+ synthase: thiamine molybdate a 5,10-methylenetetrahydrofolate a 5,10-methenyltetrahydrofolate 3-hydroxyacyl-CoA tRNA diphosphatase: sulfurtransferase: cyclic pyranopterin phosphate biosynthesis ferroheme o a 3-oxodecanoyl-[acp] tetradecenoyl-CoA triacylglycerol -2,6-diaminopimeloyl- alanine) tetrapeptide predicted ribazoletransferase: SGR_RS26225 thiamine phosphate dehydrogenase: N-acetyl-D- cob(II)yrinate NAD+ synthase: nudC moeZ monophosphate (2E,6E)-farnesyl a [hydroxymethylbilane predicted degradation D-alanyl-D-alanine GlcNAc ABC SGR_RS26590 diphosphate synthase: NAD salvage pathway III IPP molybdopterin bifunctional fatty acid elongation -- saturated SGR_RS06765 muramate a sugar a sugar a,c-diamide SGR_RS26225 synthase diphosphate synthase] ES intermediate heme A synthase: ABC 3-oxoacyl-[acyl- ∆ 3 -cis-∆ 2 -trans- enoyl-CoA transporter SGR_RS26920 2 methylenetetrahydrofolate nicotinate adenine a thiocarboxylated MoaC: moaC (to nicotinamide riboside) cytidylyl molybdenum SGR_RS27885 an uncharged tRNA hydratase: a triacyl-sn of a sugar S-adenosyl-L-methionine salvage II NMN glutathione hydroxymethylbilane transporter molybdopterin dehydrogenase/ carrier-protein] enoyl-CoA RS22710 adenosylcobalamin dinucleotide [small subunit of cyclic cofactor sulfurylation -glycerol a ring-opened 7- 10 a [DNA]-3'- a 5'-phospho- a 2'- (S)-2-oxo-4- a [protein]- an N-terminal- biosynthesis + isoprenyl of molybdate: adenylyltransferase: reductase: fabG an acetoacetyl-[acp] isomerase: SGR_RS05945 triacylglycerol an L-methionyl- an N - + + O-succinyl-L- a D-tryptophanyl- a D-aspartyl- acetylxylan thiamine NADP synthase: hemC methenyltetrahydrofolate NAD NAD(P)H a plastoquinone H a (6S)-5- serotonin MoO - carbonic acid sec molybdopterin pyranopterin ferroheme i folate polyglutamylation methylguanine glu deoxyribonucleoside cys hydroxy-4-carboxy- 2 Trp L-methionyl-L- a mercapturate asp ser a tRNA a protein predicted 5'-phosphate nicotinate-nucleotide transferase: cytidylyl molybdenum modA modB SGR_RS21360 cyclohydrolase: 3-oxoacyl-ACP SGR_RS04815 lipase: a 2,3,4-saturated a 2,3,4-saturated [initiator tRNA Met ] formyltetrahydrofolate hydroxyl [DNA] [DNA] homoserine L-glutamine ATP [tRNA ] [tRNA ] synthase] phosphate phosphate a [hydroxymethylbilane in DNA formyltetrahydrofolate 5'-triphosphate 5-ureidoimidazoline molybdopterin seryl-[protein] snapalysin: ABC SAH adenylyltransferase: cys glu SGR_RS24995 cofactor (trioxo) molybdopterin SGR_RS13395 reductase (S)-3-hydroxy-(5Z) SGR_RS01155 fatty acyl CoA 3-oxoacyl-CoA 2-oxo-4-hydroxy- cofactor a sugar a sugar bis(guanylyl molybdenum thiamine- synthase] ES intermediate heme A synthase: molybdate a 1,2-diacyl- acetylxylan snpA transporter SGR_RS24750 [+ 2 isozymes] 3 adenine dinucleotide a tetrahydrofolate FabG: fabG (3E,5Z)-tetradeca- -tetradecenoyl-CoA ATP-dependent NAD(P)H-quinone 4-carboxy-5- transglutaminase carbonic adenosylhomocysteinase: phosphate NAD + SGR_RS27885 10 lipoprotein posttranslational modification sn-glycerol DNA polymerase cystathionine D-tyrosyl- D-tyrosyl- of a sugar RS22580 cofactor) biosynthesis hydroxymethylbilane an N -formyltetrahydrofolate 3,5-dienoyl-CoA 3-hydroxyacyl-CoA bifunctional DNA- methionyl-tRNA DNA ligase: dehydrogenase: bifunctional ureidoimidazoline domain-containing type I methionyl acylase: esterase: anhydrase: serine- snapalysin: SGR_RS22425 kinase: an [MCD cofactor a (3R)-3- III subunit gamma- molybdenum cofactor tRNA(Tyr) tRNA(Tyr) adenosylcobalamin NaMN nicotinamide glutamate-- MoO - NAD(+) di-trans,octa-cis synthase: hemC hydroxyferroheme i molybdopterin acyl-CoA dehydrogenase: formamidopyrimidine formyltransferase: SGR_RS31590 SGR_RS12935 folylpolyglutamate decarboxylase: protein: aminopeptidase: SGR_RS34010 SGR_RS32125 SGR_RS26990 -tRNA snpA L-homocysteine 2 SGR_RS09410 chaperone]-MCD serine bifunctional hydroxydecanoyl-[acp] a [prolipoprotein]- gamma and tau: synthase: guanylyltransferase: deacylase: deacylase: predicted nicotinamidase: cysteine ligase: molybdopterin molybdopterin diphosphatase: -undecaprenyl molybdotransferase a 3-oxoacyl-[acp] 3-oxoacyl- thioesterase: SGR_RS06765 acetyl-CoA C- glycosylase/ SGR_RS33505 [+ 3 isozymes] synthase/ SGR_RS13250 SGR_RS26975 map [+ 3 isozymes] [+ 3 isozymes] ligase: a peptide molybdopterin a [hydroxymethylbilane cysteine hydroxymethyltransferase: folylpolyglutamate L-cysteine NAD(P)H:quinone SGR_RS19085 SGR_RS12715 SGR_RS18575 SGR_RS19720 SGR_RS19720 ABC SGR_RS22985 SGR_RS30760 cofactor thiamine nudC diphosphate MoeA: SGR_RS18580 beta-hydroxyacyl- ACP SGR_RS22305 3-oxo-(5Z)- acyltransferase: DNA-(apurinic methionyl-tRNA dihydrofolate [+ 2 isozymes] serS a sugar a sugar 5-methyltetrahydropteroyltriglutamate- synthase] ES intermediate desulfurase: 10 SGR_RS10065 oxidoreductase: 2-oxo-4-hydroxy- undecaprenyl- 4 an N - synthase/ reductase prolipoprotein a 2-acylglycerol SGR_RS07225 or apyrimidinic synthase: [+ 16 isozymes] transporter [+ 2 isozymes] diphosphate ACP [+ 5 isozymes] tetradecenoyl-CoA formyltransferase: wrbA 4-carboxy-5- 6 acetate an L-cysteine- RS00690 - homocysteine S- nicotinate thioredoxin molybdenum cofactor diphosphate hydroxymethylbilane SGR_RS27925 molybdopterin formyltetrahydrofolate [+ 2 isozymes] dihydrofolate FabG: fabG diacylglyceryl site) lyase: mutM SGR_RS24555 a [protein] N - adenylyl acetate xylan of a sugar NMN dehydratase: SGR_RS30275 [DNA] NMN ureidoimidazoline an N-terminal S-conjugate CO H O methyltransferase: metE phosphoribosyltransferase: pathway molybdotransferase synthase: transferase: (3E,5Z)- acetyl-CoA C- succinate [(5-hydroxy-1H- molybdenum Trp asp 2 2 an L-seryl- menaquinol-7 biosynthesis γ guanylyltransferase: phosphatase: synthase: hemC cysteine ferroheme a bifunctional SGR_RS16075 AMP L-cystathionine D-tryptophan a tRNA tRNA D-aspartate -L-glutamyl- 3-oxoacyl- tetradecadienoate Carbohydrate Degradation decarboxylase: uraD met L-seryl-[protein] sec [+ 2 isozymes] SGR_RS22990 SGR_RS18575 5'-nucleotidase: SGR_RS31165 desulfurase: MoeA: SGR_RS21350 a 5,10- SGR_RS24555 SGR_RS27300 acyltransferase: [DNA] indol-3-yl)ethyl]- cofactor [tRNA ] predicted all-trans- nicotinate L-cysteine lipoate biosynthesis an oxidized a holo-[hydroxymethylbilane folylpolyglutamate demethylmenaquinol- beta-hydroxyacyl- beta- [acyl-carrier- SGR_RS07225 a [DNA]- a 5'-phospho- 2,6-diamino-4- an N-formyl- a plastoquinol NAD(P) + a (6S)-5- (S)-(+)-allantoin L-glutamine SGR_RS32860 di-trans,octa-cis SGR_RS09975 methylenetetrahydrofolate a [prolipoprotein]- 4-oxo-2-pentenal a tetrahydrofolate ABC met heptaprenyl 1,4-dihydroxy- and incorporation I thioredoxin synthase] MoO -molybdopterin synthase/ 8 biosynthesis II ACP ketoacyl- protein] glycerol D-galactose degradation I (Leloir pathway) nucleotide- [DNA] hydroxy-5-(N-methyl) L-methionyl- formyltetrahydrofolate a sugar a sugar β -undecaprenyl a [cytidylyl molybdenum 2 S-1,2-diacyl-sn- (3Z)-dodec- bis(molybdenum 1-( -D dihydrofolate bifunctional reductase: chitin degradation II (Vibrio) glycogen degradation II 3'-phosphate formamidopyrimidine met transporter RS11880 diphosphate 2-naphthoate phosphate cofactor chaperone]- cofactor a tetrahydrofolate all-trans- dehydratase: ACP glyceryl-L-cysteine 3-enoyl-CoA 2-deoxy-D-ribose degradation II [initiator tRNA ] cofactor) ribofuranosyl) synthase: folylpolyglutamate fabG of a sugar methionine an octanoyl-[acp] cytidylyl molybdenum 1,4-dihydroxy- octaprenyl SGR_RS16070 synthase ∆ ∆ β-D-galactopyranose bis(guanylyl tungstenpterin) molybdenum cofactor nicotinamide SGR_RS24555 synthase/ a (3R)-3- 3, 2-enoyl- 2-deoxy-β-D- chitin a glycogen adenosyltransferase: glutathione lipoyl(octanoyl) thioredoxin- cofactor (sulfo-dioxo) 6-naphthoate diphosphate a 2,3,4-saturatedII: fabF signal a 7,8-dihydro- β α 7,8-didemethyl- 3-(D-glyceryl) a 1-acyl-2- DNA with adenine:7,8- an N-terminal- an N-terminal- a negatively a peptide with cofactor biosynthesis hydroxyacyl-[acyl- CoA isomerase: -D-ManNAc-(1->4)- -D- + α a sugar RS05325 a sugar SGR_RS30260 disulfide guanylyltransferase: 10 dihydrofolate a (2E)-dec-2-enoyl-[acp] galactose ribopyranose CDP-glycerol MoO - phylloquinone NAD(P)H H a ribonucleoside a single H O a dipeptide (2E,6E)-farnesyl -amylose menaquinol-6 biosynthesis transferase an N - fatty acyl-[acp] peptidase II: 8-oxoguanine 2 8-hydroxy-5- -diphospho- arachidonoyl- dihydro-8- L-methionyl-L- 2 L-methionyl-L- an N-terminal a protein SGR_RS18575 synthase: carrier protein]beta-hydroxyacyl- SGR_RS04815 chitinase: GlcNAc-PP-undecaprenol GTP triphosphate GTP GTP 2-phospho- supercoiled DNA diphosphate LipB: lipB reductase: formyltetrahydrofolate menaquinone SGR_RS27085 mutarotase: in DNA molybdopterin molybdopterin deazariboflavin 5'-guanosine stranded DNA sn-glycerol oxoguanine mismatch cysteinyl-[protein] valyl-[protein] DNA L-alanine membrane 1,4-alpha- RS11700 SAM demethylmenaquinol-7 a [lipoyl-carrier protein] bis(guanylyl SGR_RS24555 enoyl-ACP ACP (2E)-dodec- SGR_RS33595 L-lactate squalene alpha-lytic GTP 6 trxB biosynthesis SGR_RS25440 cofactor 3-phosphate CTP topoisomerase dipeptidase: glucan bis(tungstenpterin) demethylmenaquinol-6 N -octanoyl-L-lysine molybdopterin) NADP dehydratase: 2-enoyl-CoA [+ 2 isozymes] synthase protease a 5,10- decarboxylase: reductase an (S-diacyl-sn- a lipoprotein [+ 2 isozymes] 2-deoxy-ribono- α bifunctional glycosyltransferase NAD(P)H-quinone IV subunit A: SGR_RS22255 branching a sugar RS05440 a sugar demethylmenaquinone cofactor demethylmenaquinone cofactor biosynthesis SGR_RS16070 an -limit dextrin bifunctional DNA- 2-phospho- bifunctional A/G-specific type I methionyl type I methionyl aminopeptidase HpnC: hpnC prodomain- guanylyl molybdenum lipoyl methylenetetrahydrofolate SGR_RS20865 FabI: fabI glyceryl)-L-cysteinyl- signal peptide enoyl-CoA 1,5-lactone a chitodextrin family 2 protein/CDP- molybdenum cofactor dehydrogenase: GTPase 2-phospho-L-lactate SGR_RS08255 enzyme: methyltransferase: methyltransferase: beta-hydroxyacyl- α-D-galactopyranose formamidopyrimidine L-lactate DNA primase/ phosphatidate adenine aminopeptidase: aminopeptidase: N: pepN membrane containing cofactor biosynthesis synthase: lipA a reduced menaquinol-8 biosynthesis [apolipoprotein] hydratase: 4-alpha- glycerol:glycerophosphate guanylyltransferase: SGR_RS12935 ObgE: obgE guanylyltransferase: presqualene glgB SGR_RS14790 molybdenum cofactor SGR_RS14790 a [lipoyl-carrier NAD + a decanoyl-[acyl-carrier protein] ACP apolipoprotein N- SGR_RS05945 glycosylase/ transferase: polymerase: cytidylyltransferase: glycosylase: map map type I DNA [+ 2 isozymes] dipeptidase: diphosphate protein: MoO - thioredoxin glucanotransferase: glycerophosphotransferase: SGR_RS18575 NAD(P)H:quinone [+ 7 isozymes] cofC amylopectin RS21475 2 guanylyltransferase: menaquinol-6 6 demethylmenaquinol-8 dehydratase: galactokinase: DNA-(apurinic SGR_RS22365 SGR_RS35740 SGR_RS09120 SGR_RS20485 [+ 2 isozymes] [+ 2 isozymes] topoisomerase: SGR_RS01670 SGR_RS20150 a sugar RS11215 a sugar molybdopterin menaquinol-7 protein]-N -[(R)- NAD kinase: acyltransferase: lnt (S)-3- malQ SGR_RS22600 oxidoreductase: synthase SGR_RS18575 dihydrolipoyl]-L-lysine demethylmenaquinol-8 SGR_RS28505 beta-ketoacyl- SGR_RS16075 galK 2-deoxy- or apyrimidinic [+ 8 isozymes] topA a proteinogenic HpnD: hpnD cofactor molybdenum cofactor [+ 2 isozymes] hydroxydodecanoyl-CoA a debranched [+ 2 isozymes] wrbA H + a peptide demethylmenaquinone + ACP synthase acyl-CoA/acyl-ACP a trans-2- an N-acyl-(S-diacyl- a chitodextrin site) lyase: mutM bis(guanylyl a CDP-1-acyl- phosphate L-lactyl-2- a relaxed DNA amino acid guanylyltransferase: NADP a 2,3,4-saturated a peptide 3-hydroxyacyl-CoA α-D-galactose D-ribonate α-limit dextrin oxidized 3PG- an apurinic site an N-terminal L- GDP an N-terminal ala a peptide squalene bis(guanylyl methyltransferase: II: fabF dehydrogenase: enoyl-[acyl- sn-glyceryl)-L- α molybdopterin) 2-arachidonoyl- diphospho- guanylyl fatty acyl-[acp] UDP- -D-glucose factor 420-0 GMP ssDNA/pppN(pN) adenine within DNA met cysteinyl-[protein] met L-valyl-[protein] a sugar RS00680 a sugar SGR_RS18575 tungstenpterin) cofactor SGR_RS14790 SGR_RS18500 carrier protein] cysteinyl-[lipoprotein] dehydrogenase: 1-phosphate CMP Gro-P-ManNAc-GlcNAc- cofactor glycerol 5'-guanosine molybdenum a [DNA]- a 5'-phospho- 7,8-dihydro- NAD(P) + phylloquinol hybrid RS13075 menaquinol-8 a 3-oxododecanoyl-[acp] [+ 7 isozymes] SGR_RS06765 4-oxo-2-pentenal PP-undecaprenol n -1 cofactor 2-deoxy- nucleotide- [DNA] 8-oxoguanine α 3-oxododecanoyl-CoA 3-dehydro- -D- 3'-phosphate 3-oxoacyl-[acyl- beta-N- D-glucopyranose a sugar RS22625 a sugar enoyl-ACP D-ribonate glucopyranose carrier-protein] periplasmic disulfide bond formation acetyl-CoA C- acetylglucosaminidase reductase 1-phosphate a nascent peptidoglycan a [prokaryotic 7,8-didemethyl- enolpyruvoyl- an N-terminal- cyclic UDP-N-acetyl- an N-terminal- (9Z,12Z)-15,16- a (1->4)- reductase: fabG biotin-carboxyl carrier acyltransferase: a purine base D-cellobiose 37 4-methyl-3- RS33645 FabI: fabI domain-containing ROK family an adenosine succinyl-CoA glycerophosphoserine α a DNA segment α a [DsbB protein] a [DsbA protein] two reduced SGR_RS07225 lesion in DNA (meso-DAP containing) ubiquitin-like protein] 8-hydroxy-5- 2-diphospho- 6'-phosphate DMAPP oxoadipate L-methionyl-L- dehypoxanthine -D-glucosamine L-methionyl- epoxyoctadeca- ethylphosphate a protein asp -D-glucan Aromatic Compound Biosynthesis 3-oxoacyl-ACP protein assembly an electron- protein: SGR_RS24290 alpha-D-glucose glucokinase: a [protein]-L-lysine in tRNA a sugar RS34340 a sugar Secondary Metabolite Biosynthesis with reduced L- carrying a cysteine residues C-terminal L-glutamate deazariboflavin 5'-guanosine threonyl-[protein] futalosine UDP-N- glycyl-[protein] 9,12-dienoate alkaline DDE-type zinc-dependent 1,4-alpha- reductase transfer quinone beta-N- phosphate-specific SGR_RS06215 epoxide bifunctional a [biotin carboxyl- cysteine residues disulfide bond in a protein decanoyl-CoA acetylglucosamine phosphatase: integrase/ metalloprotease: glucan FabG: fabG D-glyceroyl-CoA acetoacetate acetylhexosaminidase: phosphoglucomutase: bifunctional DNA- lytic murein 6-phospho-beta- 3-oxoadipate- hydrolase: aspartate streptorubin B biosynthesis chorismate biosynthesis I 2,3-dihydroxybenzoate carrier protein]-L-lysine ROK family 2-phospho- tRNA (adenosine(37)-N6) glycerophosphoryl 1,4-dihydroxy- 2-epimerase (non- SGR_RS29630 transposase/ SGR_RS20275 branching platensimycin biosynthesis methylerythritol phosphate pathway I acyl-CoA/acyl-ACP SGR_RS22830 SGR_RS33600 formamidopyrimidine transglycosylase: Pup--protein glucosidase: -succinyl-CoA type I methionyl type I methionyl SGR_RS23995 transaminase/ echinomycin and triostin A biosynthesis biosynthesis a (3R)-3- biotin--[acetyl- N,N'- N,N',N''- glucokinase: L-lactate -dimethylallyltransferase diester 6-naphthoate hydrolyzing): wecB recombinase: enzyme: a sugar RS22820 a sugar RS33520 D-erythrose dehydrogenase: acetoacetate- glycosylase/ SGR_RS27580 ligase: pafA SGR_RS24255 transferase aminopeptidase: aminopeptidase: epoxide bifunctional zinc-dependent aspartate 4- Amine and Polyamine Biosynthesis hydroxydodecanoyl-[acp] CoA-carboxylase] diacetylchitobiose triacetylchitotriose [+ 2 isozymes] SGR_RS26815 transferase: MiaA: miaA phosphodiesterase: synthase: UDP-N- SGR_RS35105 glgB acetyl-CoA D-glyceraldehyde 4-phosphate SGR_RS17850 -CoA ligase: DNA-(apurinic [+ 3 isozymes] subunit B: map map hydrolase: RNase H/acid metalloprotease: decarboxylase: GGPP pyruvate chorismate ligase: beta-N- 6-phospho-beta- SGR_RS24450 SGR_RS15710 acetylglucosamine [+ 2 isozymes] a glycogen 3-phosphate 3-deoxy-7- beta-hydroxyacyl- SGR_RS30655 or apyrimidinic SGR_RS22365 SGR_RS06760 [+ 2 isozymes] [+ 2 isozymes] (9Z,12Z)-15,16-SGR_RS02980 phosphatase: a DNA segment SGR_RS11450 SGR_RS23555 ATP quinoxaline- SGR_RS12895 [+ 10 isozymes] acetylhexosaminidase: N6-([prokaryotic glucosidase: 6 [+ 6 isozymes] 2-epimerase (non- ketoacyl-ACP ectoine biosynthesis spermidine biosynthesis III phosphoheptulonate isochorismate ACP UDP-glucose:α- D-glycerate site) lyase: mutM a mature peptidoglycan a nascent peptidoglycan N -(3-methylbut- dihydroxyoctadeca- SGR_RS26005 in reverse a peptide ala a sugar RS06435 a sugar synthase III: 2-carboxylate putrescine synthase class synthase DhbC: dhbC dehydratase: a [biotin carboxyl-carrier UDP-glucose acetoacetyl-CoA SGR_RS22830 ubiquitin-like protein]- SGR_RS05135 2-en-1-yl)- hydrolyzing): wecB 1-deoxy-D- (2E)-dec-2-enoyl-CoA D-galactose- with (L-alanyl-γ-D-glutamyl- (meso-DAP containing) α 9,12-dienoate ethanol orientation biosynthesis I 6 4-epimerase ribose γ dehydro 37 an N-terminal L- 1,4-dihydroxy- an unknown UDP-N-acetyl- - an N-terminal RS33385 SGR_RS25465 3-deoxy- II: SGR_RS26860 isochorismate SGR_RS16075 protein]-N -biotinyl-L-lysine 1-phosphate glycerate kinase: beta-N- -L-glutamyl)- adenosine 4-methyl-3- sn-glycerol xylulose-5- asp GalE: galE SGR_RS25505 acetyl-CoA C- phosphorylation a [DNA]- meso-2,6-diaminopimeloyl- with GlcNAc terminus factor 420-0 GMP succinate ser met threonyl-[protein] 6-naphthoate compound D-mannosamine met glycyl-[protein] [+ 2 isozymes] arg SAM D-arabino- beta-hydroxyacyl- enoyl-CoA uridylyltransferase: acetylglucosaminidase a 5'-phospho- a modified [protein]-L-lysine D-glucopyranose in tRNA oxoadipyl-CoA 3-phosphate (-)-ent-copalyl phosphate aspartate kinase: [+ 3 isozymes] acyltransferase: nucleotide- 4-oxo-2-pentenal D-alanine) tetrapeptide D-glucopyranose arg heptulosonate isochorismatase: ACP hydratase: α galT glycerate kinase: domain-containing β [DNA] nucleobase 6-phosphate a sugar RS23575 a sugar diphosphate synthase: SGR_RS16690 -D-glucopyranose α SGR_RS07225 -D-ribopyranose 3'-phosphate an acetoacetyl-[acp] quinoxaline-2- 7-phosphate SGR_RS33610 dehydratase: SGR_RS05945 UDP- -D-galactose SGR_RS05790 protein: SGR_RS24290 D-ribose SGR_RS07310 aspartate kinase: a [biotin carboxyl- 1-phosphate [+ 6 isozymes] D-glucopyranose RS20555 carboxyl adenylate 3-dehydroquinate (2S,3S)-2,3-dihydroxy- SGR_RS16070 carrier-protein dimer]- DsbA family (S)-3- 2-phospho- N-acetyl-D- pyranase: SGR_RS21110 6-phosphate 5-amino-5-(4- a [TusE sulfur 7,8-didemethyl- L-lactyl-2- α (12Z,15Z)-9,10- a (1->4)- 3-oxoacyl- 1-deoxy-D-xylulose acyl carrier agmatine synthase: 2,3-dihydrobenzoate N 6 -biotinyl-L-lysine oxidoreductase: hydroxydecanoyl-CoA alpha-D-glucose D-glycerate acetyl-CoA glucosamine rbsD 3-phospho- an NDP- - a [DNA]-3'- a sugar RS00945 a sugar L-aspartyl- palmitoyl-CoA a uridine 34 in tRNA H O an N-acylated- (S)-2- protoheme 4-hydroxy- oxaloacetate citrate β-D-allopyranose α [acyl-carrier- agmatine dAdoMet SGR_RS30165 a (2E)-dodec-2-enoyl-[acp] SGR_RS28065 3-hydroxyacyl-CoA hydroxybenzyl)- SAM a ferrocytochrome b carrier protein]-S 8-hydroxy-5- diphospho- D-glucose diphosphate 2 glu a type IV prepilin epoxyoctadeca- asp -D-glucan (16R)-ent- 5-phosphate protein: 4-phosphate acetyl-CoA a [DsbB protein] a [DsbA protein] phosphate-specific D-ribose 5 D-glycerate hydroxyl 2,3-dihydro-2,3- an electron- an intra- chitobiose degradation 6-(D-ribitylimino) -sulfanylcysteine deazariboflavin 5'-guanosine D-amino acid aminobutanoate L-threonine 12,15-dienoate citrate synthase/ D-ribose 1,4-alpha- protein] kauran-16-ol SGR_RS25460 agmatinase: carboxylase biotin carrying a with reduced L- dehydrogenase: phosphoglucomutase: pyranase: epoxide bifunctional 1-deoxy-D-xylulose- 3-dehydroquinate dihydroxybenzoate transfer quinol protein disulfide pyranase: glucan reductase: aspartate- speB enoyl-ACP disulfide bond cysteine residues SGR_RS06765 SGR_RS33600 -5,6-dihydrouracil hydrolase: methylcitrate 5-phosphate [+ 4 isozymes] polyamine dehydrogenase: dhbA subunit beta: carboxylase: N,N'-diacetylchitobiose rbsD glucosyl-3- exodeoxyribonuclease deferrochelatase/ citrate lyase aspartate rbsD branching a sugar RS24265 a sugar RS20370 fabG a quinoxaline-2- semialdehyde reductase [+ 2 isozymes] D-xylose β acyl-CoA desaturase: tRNA 2- 2-phospho- inorganic D-aminoacylase: glutamate-- prepilin low specificity SGR_RS23995 synthase: reductoisomerase: aminopropyltransferase: type II 3- SGR_RS23695 SGR_RS15300 3-oxodecanoyl-CoA 6'-phosphate -D-ribofuranose phosphoglycerate III: xth peroxidase EfeB: efeB subunit beta: transaminase/ enzyme: 3-oxoacyl- dehydrogenase: putrescine 2,3-dihydroxybenzoate FabI: fabI degradation I fructose degradation SGR_RS01625 thiouridine(34) L-lactate diphosphatase: SGR_RS20985 cysteine ligase: peptidase: L-threonine SGR_RS08265 D-ribose SGR_RS08940 ala carboxyl-[aryl- ser SGR_RS16945 dehydroquinate [+ 2 isozymes] D-glucopyranose bifunctional FO synthase: exodeoxyribonuclease ferrochelatase: epoxide SGR_RS27305 aspartate 4- glgB ACP (16R)-ent- carrier protein] SGR_RS16685 biosynthesis acyl-CoA desaturase: synthase transferase: SGR_RS20265 D-aminoacylase: SGR_RS30760 SGR_RS12365 aldolase: citrate pyranase: dehydratase: aroQ a dodecanoyl-[acp] a [carboxyl-carrier acetyl-CoA C- 6-phosphate β-D-fructofuranose SGR_RS15980 III: xth SGR_RS08175 hydrolase: decarboxylase: kauran-16,19-diol 1 Cell Structure Biosynthesis peptidoglycan maturation (meso-diaminopimelate containing) 6 6 37 N-monoacetylchitobiose D-xylose [+ 2 isozymes] synthase 2: rbsD starch reductase MEP aspartate- N -(3- protein dimer]-N - N -L-threonylcarbamoyladenosine acyltransferase: protein CofGH: SGR_RS01955 MnmA: mnmA SGR_RS22365 SGR_RS12555 [+ 2 isozymes] SGR_RS32570 (12Z,15Z)-9,10-SGR_RS02980 SGR_RS23555 a sugar RS06925 a sugar 3-dehydroshikimate 6'-phosphate xylose 1-phosphate SGR_RS15220 β FabG: fabG semialdehyde aminopropyl) carboxybiotinyl-L-lysine Glycolysis -modified tRNA biosynthesis SGR_RS07225 1-phosphofructokinase: SGR_RS21035 dihydroxyoctadeca- acetate oxaloacetate oxaloacetate -D-allofuranose RS33075 lipid II (meso isomerase: D-ribofuranose 2-O-(α-D- a [DNA]-3'- a 2'- a cleaved type (2S,3S)-2- a (3R)-3- 2-C-methyl-D- dehydrogenase: agmatine 6-phospho-beta- pfkB 34 a nucleoside 2+ a peptide beta-ketoacyl- + γ Fe protoporphyrin IX 12,15-dienoate diaminopimelate containing) shikimate octanoyl-CoA xylA β-D-fructose 1,6- a 2-thiouridine a [TusE sulfur carrier oxidized glucopyranosyl) hydroxyl deoxyribonucleoside H -L-glutamyl-(S)- IV prepilin glycolaldehyde methylcitrate hydroxybutanoyl- (16R)-hydroxy- erythritol 4-phosphate a quinoxaline- SGR_RS24340 ACP synthase thr glucosidase: ribokinase: 7,8-didemethyl- palmitoleoyl-CoA a ferricytochrome b diphosphate phosphate a carboxylate a D-amino acid gly peptidoglycan dehydrogenase: glycolysis III (from glucose) D-xylulose bisphosphate 5 in tRNA protein]-L-cysteine factor 420-0 GMP -3-phospho- 5'-monophosphate 2-aminobutanoate a sugar RS26315 a sugar [acp] ent-kauran- cytidylyltransferase: 2-carboxyl-D- spermidine 3-(4-hydroxyphenyl) II: fabF threonylcarbamoyl-AMP SGR_RS24255 SGR_RS00695 5'-deoxyadenosine 8-hydroxy-5- met beta-hydroxyacyl- L-aspartate 4- glycosyltransferase: SGR_RS30155 acyl-CoA/acyl-ACP D-glycerate 19-oate SGR_RS19905 seryl-L-alanyl- biosynthesis I pyruvate laurate synthase: SGR_RS01400 6-phospho-beta- xylulokinase: [+ 2 isozymes] deazariboflavin ACP semialdehyde ftsW fatty acid biosynthesis D-glucopyranose dehydrogenase: RS33015 4-(cytidine 5'- cys [non-ribosomal val spermidine shikimate biosynthesis glucosidase: xylB D-ribofuranose dehydratase: diaminobutyrate- a nascent peptidoglycan threonylcarbamoyl-AMP SGR_RS17850 diphospho)-2-C- peptide synthase] SAM a 3-oxotetradecanoyl-[acp] long-chain fatty initiation (type II) SGR_RS05135 5-phosphate predicted SGR_RS16075 -2-oxoglutarate with (L-alanyl-γ-D-glutamyl- tyr acid--CoA ligase: ROK family synthase: SGR_RS10685 [+ 10 isozymes] D-xylulose a [ribosomal a 2-oxo a DNA containing a mycothiol (9Z,15Z)-12,13- 3''-O-acetyl- a supercoiled [4-(6-methyloctanoyl) methyl-D-erythritol shikimate kinase: (L-threonylcarbamoyl)adenylate N-acetyl-D-glucosamine a sulfurated a sulfurated [CysO sulfur- 3-phospho- ADP-α-D-glucose an N-modified S-methyl-L- ABC (11S,16S)-ent transaminase: ectB meso-2,6-diaminopimeloyl-D- glucokinase: 5-phosphate protein S12] ala a pimeloyl-[acp] DL-allothreonine glycerophosphoglycerol carboxylate L-ornithine L-homocysteine cys L-homocysteine epoxy-octadeca- ADP-ribose -5-oxo-2H-furan-3- 5-MTR-1-P a protein a sugar a sugar beta-hydroxyacyl- 4-(cytidine 5'- SGR_RS30165 bifunctional 3-oxoacyl-[acyl- SGR_RS17830 acetyl-CoA 6-phosphate [sulfur carrier] carrier protein] D-glycerate aminoacyl-[tRNA] methionine a mismatch S-conjugate duplex DNA transporter -kauran-11,16- SGR_RS06215 (2E)-oct-2-enoyl-CoA [sulfur carrier] L-aspartate 89 9,15-dienoate UvrD-helicase yl]methyl phosphate ACP diphospho)- L-2,4- alanyl-D-alanine) pentapeptide aspartate carrier-protein] [+ 10 isozymes] acetyl-CoA tRNA (adenosine(37)-N6)- epoxide butenolide S-methyl-5- of a sugar epoxy-19-oate shikimate 3- ROK family domain- RS32900 dehydratase: 2-C-methyl-D- myo-inositol diaminobutanoate transaminase/ reductase: fabG carboxylase subunit threonylcarbamoyltransferase enoyl-CoA hydrolase: O-acetyl- phosphate thioribose-1- proteasome triostin A dithiol penicillin-binding phosphate lauroyl-CoA glucokinase: glucosyl-3- glycerophosphodiester ornithine- G/U mismatch- mycothiol containing SGR_RS16070 erythritol kinase: biosynthesis D-alanyl-D-alanine aspartate 4- beta: SGR_RS23695 complex: tsaD tsaB tsaE hydratase: 30S ribosomal 8-amino-7- adenylyltransferase/ serine peptidyl-tRNA homocysteine S- cystathionine SGR_RS23995 ADP-ribose reductase phosphate ATPase: arca sugar RS15900 a sugar diaminobutyrate putrescine dAdoMet protein 2: 3-oxoacyl-ACP SGR_RS26815 phosphoglycerate phosphodiesterase: -oxo-acid specific DNA conjugate protein: SGR_RS21645 carboxypeptidase/ 3-phosphoshikimate 1- decarboxylase: [+ 2 isozymes] SGR_RS05945 protein S12 oxononanoate sulfurtransferase hydroxymethyltransferase: hydrolase: methyltransferase: beta-synthase: deacetylase: [(3S,4R)-4-(6-BprA: bprA isomerase: a (2E)-but- D-glucopyranose acetyltransferase: SGR_RS21020 a mature peptidoglycan with reductase an N 6 -L-threonylcarbamoyladenine 37 in tRNA synthase: SGR_RS17900 transaminase: glycosylase: amidase epoxide SGR_RS22775 an unfolded (7S,11S,16S)- 2-phospho-4-(cytidine D-alanyl-D-alanine- carboxyvinyltransferase: 3-(4- SGR_RS23555 malonyl-CoA D-glucopyranose methylthiotransferase synthase: MoeZ: moeZ SGR_RS10065 SGR_RS07165 mmuM SGR_RS22120 SGR_RS05860 methyloctanoyl)- S-methyl-5-mtnA 2-enoyl-[acp] 6-phosphate ectA (L-alanyl-γ-D-glutamyl-meso- FabG: fabG (S)-3- SGR_RS15980 [+ 6 isozymes] rocD mug Mca: mca hydrolase: protein 7-hydroxy-ent 5'-diphospho)-2-C- inositol-3- fused MFS/ endopeptidase: dacB [+ 4 isozymes] aroA hydroxyphenyl) 6-phosphate RimO: rimO SGR_RS31410 [+ 2 isozymes] [+ 2 isozymes] [+ 7 isozymes] 5-oxooxolan-3- thio-D-ribulose RS10540 2,6-diaminopimeloyl-D-alanyl- ACP S- hydroxyoctanoyl-CoA (9Z,15Z)-12,13-SGR_RS02980 a single a sugar RS09320 a sugar enoyl-ACP -kauran-11,16- methyl-D-erythritol phosphate (2S)-4-acetamido- spermidine penicillin-binding 3-phosphoshikimate 1- pyruvate a (3R)-3- glucose-6- selenate reduction Inorganic Nutrient Metabolism a [CysO sulfur- yl]methyl phosphate 1-phosphate 2-C-methyl-D- triostin A 2-aminobutanoate a nascent peptidoglycan D-alanine) pentapeptide hydroxytetradecanoyl-[acp] malonyltransferase: 3-hydroxyacyl-CoA assimilatory urea cycle an unsulfurated 2-O-(α-D- an apyrimidinic uracil dihydroxyoctadeca- ADP-D-ribose stranded DNA reductase epoxy-19-oate synthase: synthase: protein 2: mrdA carboxyvinyltransferase: stearate biosynthesis phosphate polyphosphate a [ribosomal carrier protein]- glycerol sn-glycerol a proteinogenic L-glutamate-5- met L-cystathionine GlcN-Ins acetate erythritol 2,4- with D,D cross-links (meso- SGR_RS25470 dehydrogenase: sulfate reduction IV (8S)-8-amino-7- [sulfur carrier] ADP glucopyranosyl) an uncharged site in DNA a mercapturate 9,15-dienoate FabI: fabI SGR_RS05410 ectoine SGR_RS23535 aroA beta-hydroxyacyl- II (bacteria and plants) isomerase: pgi metabolism 5'-deoxyadenosine protein S12]-3- an unsulfurated acyl-carrier protein thiocarboxylate acetaldehyde 3-phosphate amino acid semialdehyde an N-modified cyclodiphosphate a nascent peptidoglycan diaminopimelate containing) [+ 2 isozymes] SGR_RS06765 selenate met oxononanoate -3-phospho- gly tRNA synthase: [+ 4 isozymes] 5-enolpyruvoyl- ACP arg methylsulfanyl- [sulfur carrier] amino acid a sugar RS12530 a sugar synthase: inositol-3- with (L-alanyl-γ-D-glutamyl- F6P sulfate sulfate long chain D-glycerate RS10460 a butanoyl-[acp] SGR_RS28095 shikimate 3- dehydratase: 3-oxooctanoyl-CoA 89 (11S,16S)- phosphate meso-2,6-diaminopimeloyl- a palmitoyl-[acp] a malonyl-[acp] adenylyltransferase sulfate polyphosphate L-aspartate SGR_RS19910 echinomycin phosphate SGR_RS16075 sulfate activation beta- 7-oxo-ent- synthase: ectoine spermidine D-alanine) tetrapeptide beta-ketoacyl- 6-phosphofructokinase: TCA cycle TCA cycle IV (2-oxoglutarate decarboxylase) acetyl-CoA C- subunit CysD: cysD adenylyltransferase asp 2-C-methyl-D-erythritol- a mature peptidoglycan chorismate adenosine 5'- assimilatory for sulfonation glycine glycine ketoacyl- kauran-11,16- SGR_RS18230 beta-hydroxyacyl- ACP synthase ketoacyl-ACP SGR_RS31520 acyltransferase: subunit CysD: cysD sulfate reduction III (1S,2R)-1- an N-acylated 2''-O-acetyl- RS22915 with D,D cross-links (meso- synthase: phosphoselenate a [protein]- a DNA methyl a D-aminoacyl- + a dipetide with an N- 5-deoxy-D- betaine betaine epoxy-19-oate 2,4-cyclodiphosphate Ins(3)P L,D-transpeptidase: L,D-transpeptidase: ACP II: fabF synthase III: 6-phosphofructokinase: APS polyphosphate cob(II)inamide pyruvate 2,3- a holo-[VibB aryl- pimeloyl-CoA aci-nitroethane malonyl-CoA H vernolate salicyl-CoA acetyl-CoA ACP aspartate kinase: diaminopimelate containing) aroC a 3-oxooctadecanoyl- oxaloacetate citrate synthase/ SGR_RS07225 sulfate ATP 2,3-dihydroxybenzoate aryl-carrier protein L-cysteine phosphotriester ser C-(indol-3- ala [tRNA] aliphatic-L- terminal L-aspartate ADP-ribose IMP glucuronate flavodoxin- SGR_RS13740 SGR_RS13740 dehydratase: SGR_RS25465 SGR_RS10370 ammonium kinase 2: ppk2 dihydroxybenzoate carrier protein] epoxide RS10235 synthase SGR_RS16690 [acp] sphingomyelin metabolism methylcitrate synthase: sulfate sulfate yl)glycerol amino acid bifunctional acetyl-CoA 5-deoxy- II: fabF dependent inositol a nascent peptidoglycan with a mature peptidoglycan chorismate SGR_RS16070 [+ 2 isozymes] β-D-fructose 1,6- hexanoyl-CoA adenylyl-sulfate sulfate [+ 2 isozymes] 3-phosphate hydrolase: salicylyl-CoA carboxylase glucuronate aspartate kinase: Other Biosynthesis SGR_RS08265 argininosuccinate glutamine- adenylyltransferase O-acetyl- (E)-4-hydroxy- monophosphatase: a nascent peptidoglycan (L-alanyl-γ-D-glutamyl-meso- a nascent peptidoglycan with (L-alanyl-γ-D-glutamyl- 3-oxoacyl- bisphosphate kinase: cysC adenylyltransferase pyruvate, methylated-DNA-- nitronate type III dipeptidase SGR_RS23995 5-hydroxylase/ subunit beta: 5'-nucleotidase: isomerase:a purine RS06380 a purine SGR_RS21110 (7R,11S,16S)- γ an N-acyl- citrate synthase: acyl-CoA/acyl-ACP selenite lyase: argH subunit CysD: cysD cob(I)yrinic acid a,c-diamide (2,3-dihydroxybenzoyl) (2,3- 8-amino-7- D-tyrosyl- ADP-ribose a 3-oxohexanoyl- 3-methylbut- SGR_RS05870 with L,D cross links (meso- with (L-alanyl- -D-glutamyl- a (2E)-tetradec-2-enoyl-[acp] [acyl-carrier- an acetoacetyl-[acp] hydrolyzing phosphate [protein]-cysteine S- tryptophan monooxygenase: acylase: polyketide SGR_RS32860 7-hydroxy-ent 2,6-diaminopimelate) tripeptide meso-2,6-diaminopimeloyl- sphingosylphosphorylcholine SGR_RS24025 dehydrogenase: L-arginino- subunit CysD: cysD APS adenosyltransferase: cobO adenylate synthase: dihydroxybenzoyl) oxononanoate tRNA(Tyr) PepE: pepE epoxide deacetylase: oxidoreductase: SGR_RS23695 5-dehydro-iolB [acp] L-aspartyl- 2-enyl- L-dopa and L- diaminopimelate containing) meso-2,6-diaminopimeloyl- protein] PAPS L-ornithine carbamoyl- APS long chain dikinase: methyltransferase: synthase: trpB SGR_RS24895 SGR_RS34010 synthase: -kauran-11,16- inositol D-alanine) tetrapeptide class II fructose- SGR_RS17850 succinate cob(I)yrinic acid a,c-diamide SGR_RS33620 adenylate synthase: synthase: deacylase: hydrolase: SGR_RS05860 SGR_RS07670 [+ 2 isozymes] 2-deoxy-D- RS19125 4-phosphate diphosphate dopachrome glycine) tetrapeptide enoyl-ACP reductase: phosphate polyphosphate SGR_RS25155 SGR_RS27705 SGR_RS27290 [+ 2 isozymes] SGR_RS33090 3-oxoacyl- epoxy-19-oate monophosphatase: sphingomyelin bisphosphate malate dehydrogenase: phosphoadenylyl- adenylyl-sulfate adenosyltransferase: SGR_RS33620 SGR_RS31410 SGR_RS19720 SGR_RS02980 gentisyl-CoA malonyl-CoA inosine gluconate a purine RS06390 a purine synthase: ispG biosynthesis reductase fabG [+ 10 isozymes] argininosuccinate synthase: phosphoadenylyl- [+ 2 isozymes] (9Z)-12,13- [acyl-carrier- aspartate- SGR_RS08170 a mature peptidoglycan with phosphodiesterase: aldolase: fbaA (S)-malate SGR_RS13380 citrate sulfate reductase: kinase: cysC SGR_RS10595 a proteinogenic (E)-4-hydroxy-3- FabI: fabI 3-oxoacyl- synthase: argG carA carB sulfate reductase: glyphosate D-glyceraldehyde an aliphatic a carboxylate asp dihydroxyoctadeca- protein] a mature peptidoglycan γ selenodiglutathione phosphoenol + a 2,3-dihydroxybenzoyl- amino acid ADP-D-ribose semialdehyde tyr (L-alanyl- -D-glutamyl-meso- sph (2E)-hexenoyl-CoA SGR_RS06810 SGR_RS06810 degradation II H a 2,3- 3-phosphate trp acetaldehyde nitrite octoketide 9-enoate acetate reductase: methylbut-2-en- myo-inositol with L,D cross-links (meso- a mature peptidoglycan ACP sphingosylphosphorylcholine fumarate hydratase: argininosuccinate carbamoyl PAPS pyruvate diphosphate [aryl-carrier protein] (8S)-8-amino-7- an uncharged L-amino acid dehydrogenase: 2,6-diaminopimelate) tripeptide a myristoyl-[acp] AMP dihydroxybenzoyl- a [protein]-S- coenzyme A a D-amino acid 2+ 2+ fabG (7R,11S,16S 1-yl diphosphate tyrosinase: diaminopimelate containing) with (L-alanyl-γ-D-glutamyl- Metabolic Regulator Biosynthesis reductase triose-phosphate SGR_RS12220 enoyl-CoA sulfite synthase: phosphate adenosylcobinamide [DNA] oxononanoate tRNA Co CbiQ Co RS04915 SGR_RS16685 4-hydroxy-3- a sphingosine aconitate hydratase ornithine sulfite triphosphate [VibB] methyl-L-cysteine )-7-hydroxy- SGR_RS02500 meso-2,6-diaminopimeloyl- FabG: fabG isomerase: hydratase: SGR_RS29770 glyphosate 3-oxoacyl- methylbut-2-enyl beta-ketoacyl- ceramide class II fumarate AcnA: acnA carbamoyltransferase: aspartate- ent-kauran- dopaquinone glycine) tetrapeptide a (3R)-3- SGR_RS27805D-glyceraldehyde SGR_RS05945 octaheme sulfite assimilatory sulfite ACP diphosphate ppGpp metabolism ACP synthase DHAP hydratase: SGR_RS12270 argF semialdehyde 11,16-epoxy- mannosylglucosylglycerate trehalose trehalose biosynthesis V hydroxyoctadecanoyl- 3-phosphate (S)-3- glutathioselenol reductase: reductase (NADPH) glycine reductase: trehalose biosynthesis II II: fabF 6 sulfite RS04255 sulfite reductase dehydrogenase: 19-oyl-AMP biosynthesis I biosynthesis IV [acp] fumarate cis-aconitate SGR_RS06800 phosphate an (S-diacyl-sn- an O - a peptide with SGR_RS12175 type I hydroxyhexanoyl-CoA L-citrulline : SGR_RS06800 oxidase an L-1- a [protein]- an (S)-2- a [protein]- DNA containing a (2E,4E)-2,4- a [protein]-L- FabG: fabG SGR_RS24340 4-hydroxy-3- pppGpp a glycogen beta-hydroxyacyl- aconitate hydratase acquisition cob(II)alamin glyceryl)-L-cysteinyl- 3-methylbutanoate methylguanine a [protein]-L-lysine an N-terminal a tRNA precursor oxaloacetate sarcosine RNA aminomalonate a 28S rRNA a protein RS32055 a (3R)-3- 2-methylisoborneol 3-phospho- D-glucopyranose a 3-oxohexadecanoyl-[acp] glyceraldehyde- 3-hydroxyacyl-CoA hydrogen sulfide ThiO: thiO ATP phosphatidylethanolamine L-cysteine ATP halocarboxylate L-glutamine a base with lesion dienoyl-CoA methionine methylbut-2-enyl IPP bifunctional (p)ppGpp UDP-α-D-glucose α-maltose glycogen debranching ADP-α-D-glucose ACP succinate dehydrogenase/ AcnA: acnA hydrogen sulfide [apolipoprotein] in DNA a tRNA precursor L-proline citrate synthase/ bifunctional NADPH- RICIN domain- peptide- hydroxyhexanoyl- L-aspartate 4- biosynthesis D-glycerate 6-phosphate 3-phosphate dehydrogenase: a phosphate CTP Co 2+ Co 2+ diphosphate leucodopachrome synthetase/guanosine- maltose alpha-D- protein GlgX: glgX dehydratase: fumarate reductase methylcitrate aspartate dependent 2,4- containing methionine RS11665 [acp] semialdehyde (7R,11S,16S 3-oxoacyl-[acyl- dehydrogenase: iron-sulfur subunit: SGR_RS06765 monoester (aminomethyl) acetate- HAD family transglutaminase G/U mismatch- proteasome: Mg 2+ Mg 2+ reductase: geranyl 3',5'-bis(diphosphate) 3'- glucosyltransferase: glycogen debranching SGR_RS16075 hydrogen selenide bifunctional glyoxylate apolipoprotein methylated-DNA-- synthase: ribonuclease transaminase/ dienoyl-CoA protein: (S)-S-oxide beta-hydroxyacyl- )-7-hydroxy- isopentenyl- glucosyl-3- trehalose-6- carrier-protein] gap SGR_RS03375 phosphonate cob(I)yrinic acid a,c-diamide -CoA hydrolase: domain-containing specific DNA prolyl ribonuclease D: glycine oxidase prcB prcA 2-amino-4, 5- SGR_RS12175 diphosphate pyrophosphohydrolase: treS protein GlgX: glgX 3-oxohexanoyl-CoA RNase H/acid acyltransferase: [protein]-cysteine S- CCA tRNA SGR_RS08265 PH: rph aspartate 4- reductase: SGR_RS33360 reductase predicted ACP ent-kauran- diphosphate geranyl phosphoglycerate α α phosphate reductase: fabG beta-hydroxyacyl- adenosyltransferase: ligase: acs glycosylase: SGR_RS07220 dihydroxy-6-oxo- SGR_RS30080 , -trehalose a maltodextrin glyceraldehyde- [+ 2 isozymes] phosphatase: SGR_RS06015 methyltransferase: nucleotidyltransferase: SGR_RS20580 protein: aminopeptidase: pip citrate synthase: ThiO: thiO decarboxylase: SGR_RS03975 [+ 3 isozymes] MsrA: msrA ABC dehydratase: 11,16-epoxy- Delta- guanosine 3'- synthase: synthase: ACP succinate D-threo-isocitrate SGR_RS10595 mug a protein-L- a peptide Co 2+ Co 2+ ectoine ectoine 7-(phosphonooxy) diphosphate 2-C- 3-oxoacyl-ACP 3-phosphate acetyl-CoA C- SGR_RS27705 SGR_RS18240 [+ 9 isozymes] SGR_RS26975 SGR_RS23555 a (2E)-2- a 28S rRNA CorA transporter 19-oyl-CoA L-dopachrome bifunctional (p)ppGpp diphosphate 5'- SGR_RS15980 SGR_RS15985 dehydratase: NADP-dependent SGR_RS26005 [+ 2 isozymes] SGR_RS24025 2+ 2+ SGR_RS16075 heptanoate isomerase: idi methyltransferase: malto-oligosyltrehalose reductase dehydrogenase: acetyltransferase: cob(I)yrinic acid a,c-diamide 1,2- a nucleoside enoyl-CoA fragments methionine- Mg Mg of ectoine synthetase/guanosine- triphosphate 3'- SGR_RS16070 isocitrate dehydrogenase: phosphate 3-methylbutanoyl- [+ 2 isozymes] RNA beta-hydroxyacyl- synthase: griI (E)-2- SGR_RS06195 synthase: treY FabG: fabG SGR_RS04535 succinate-semialdehyde SGR_RS06745 adenosyltransferase: cobO an N-acyl-(S-diacyl- diphosphate a protein with an a DNA containing a nucleoside 5'- dihydroxypropane- glyoxylate methylamine diphosphate gly (S)-S-oxide 3',5'-bis(diphosphate) 3'- diphosphatase: 2-O-(α-D- α,α-trehalose SGR_RS05970 a 2-acyl-1-lyso- AMP CoA a tRNA a (2R)-2- a modified a peptide pro a tRNA ACP 2-amino-4,5- methylgeranyl a (2E)-octadec- dehydrogenase (NADP(+) a halide anion 6 γ an apurinic/ monophosphate 1,2,3-tricarboxylate DMAPP SGR_RS30080 glucopyranosyl) 6-phosphate a (3R)-3- [+ 6 isozymes] phosphatidylethanolamine sn-glyceryl)-L- a [protein]-S- containing a hydroxy fatty acid N -( -glutamyl)- nucleobase RS09640 dehydratase: dihydroxy-6-oxo- diphosphate pyrophosphohydrolase: a maltooligosyl-trehalose 2-enoyl-[acp] 13-DPG ): SGR_RS13575 Amino Acid Degradation adenosylcobalamin a guanine in DNA apyrimidinic site 2+ 2+ (4S)- -3-phospho- GDP-α-D- hydroxyhexadecanoyl-[acp] cysteinyl-[lipoprotein] 3' CCA end L-lysine crosslink Mg RS11680 Mg SGR_RS16070 7-(phosphooxy) 2-methylisoborneol SGR_RS08440 trehalose- butanoyl-CoA triphosphate methyl-L-cysteine homoplatensicyl- D-glycerate mannose enoyl-ACP heptanoate CoA synthase: malto-oligosyltrehalose phosphatase: beta-hydroxyacyl- phosphoglycerate L-valine degradation I a (2E)-hex- a sulfur-carrier reductase succinate semialdehyde 2-oxoglutarate acyl-CoA/acyl-ACP L-isoleucine degradation I L-leucine degradation I L-arginine degradation V L-aspartate 3-amino-4- SGR_RS06200 trehalohydrolase: treZ otsB ACP kinase: L-arginine degradation L-threonine degradation I 2-enoyl-[acp] glucosylglycerate FabI: fabI (arginine deiminase pathway) degradation I 2+ 2+ protein with a C- dehydratase: dehydrogenase: XIII (reductive 4 Mg MgtA Mg hydroxybenzoic biosynthesis I α α SGR_RS27800 UDP-N-acetyl-α-D-muramoyl- a 2-oxo an O - N-acetyl-D- an [amino-group an N-hydroxy- a triacyl-sn a protein-L- RS09605 terminal Gly-Gly methylerythritol phosphate pathway II 2-methylisoborneol α,α-trehalose , -trehalose SGR_RS16075 SGR_RS17850 di-trans,octa-cis- coenzyme A an apo [peptidyl- a [protein]- hop-22(29)-ene an (R)-2- an alkylated DNA N-ethylglycine a (2E,4Z)-2,4- squalene enoyl-ACP acid a stearoyl-[acp] val ile Stickland reaction) L-alanyl-γ-D-glutamyl-L- carboxylate methylthymine SAM a PII protein galactosamine carrier protein]- arylamine Ins(1)P -glycerol a protein methionine- homoplatensic- GTP ppGpp 2-[2-O-(α-D- 3-phospho- trehalose biosynthesis I 3-phospho-D-glycerate leu thr arg undecaprenyl phosphate carrier protein] L-cysteine halocarboxylate dienoyl-CoA reductase synthase: griH α beta-hydroxyacyl- [+ 10 isozymes] asp lysyl-D-alanyl-D-alanine in DNA UTP 6-phosphate C-terminal-γ-(L- arylamine N- NADPH- (R)-S-oxide squalene D-glyceraldehyde mannopyranosyl) D-glycerate GDP- -D-glucose multifunctional oxoglutarate branched-chain arg threonine inositol ATP- peptide- FabI: fabI 4-enyl-CoA pyruvate ACP phosphatidylserine and branched-chain bifunctional glutamyl)-L-glutamateacetylglutamate acetyltransferase: dependent 2,4- synthase a metal a metal 3-amino-4- 3-phosphate -(1->2)-α-D- D-glucopyranose phosphoglyceromutase: decarboxylase/oxoglutarate crotonyl-CoA branched-chain amino acid arginine ammonia-lyase: arginine 2-oxoacid:ferredoxin HAD family DNA-3- monophosphatase: triacylglycerol glycine dependent zinc methionine RS17365 a carboxy- enoyl-CoA UDP-α-D-glucose dehydratase: phosphatidylethanolamine amino acid aspartate phospho-N- holo-ACP methylated-DNA-- adenosyl- N-acetylglucosamine- kinase: SGR_RS24815 dienoyl-CoA HpnC: cation cation a hexanoyl-[acp] hydroxybenzoate glucopyranosyl]- glucosyl-3- 6-phosphate SGR_RS19870 dehydrogenase thiamine amino acid aminotransferase: deiminase: SGR_RS12660 deiminase: oxidoreductase hydrolase: methyladenine [protein-PII] SGR_RS05870 lipase: oxidase metalloprotease (R)-S-oxide CrgA adenylated hydratase: SGR_RS16070 biosynthesis I enoyl-CoA aminotransferase: (2Z)-2-aminobut- transaminase/ acetylmuramoyl- synthase: [protein]-cysteine S- hopene 6-phosphate SGR_RS17235 arylamine N- reductase: hpnC 1-deoxy-D- nucleoside- 3-phospho- phosphoglycerate pyrophosphate-binding aminotransferase: SGR_RS09750 SGR_RS07695 SGR_RS07695 subunit beta: SGR_RS20580 glycosylase: uridylyltransferase: inositol SGR_RS01155 ThiO: thiO FtsH: ftsH reductase [sulfur-carrier SGR_RS05945 bifunctional (p)ppGpp stearate hydratase: SGR_RS09750 4-methyl-2- 2-enoate aspartate 4- pentapeptide- SGR_RS13775 methyltransferase: transferase deacetylase: nagA acetylglutamate acetyltransferase: SGR_RS03975 presqualene beta- xylulose-5- diphosphate D-glycerate synthase: trehalose-6- a CDP-diacylglycerol 2-phospho-D-glycerate subunit/dihydrolipoyllysine- SGR_RS09750 L-citrulline SGR_RS14495 SGR_RS28445 SGR_RS09285 an [amino-group carrier monophosphatase: a peptide MsrB: msrB protein with a C- (3S)-3-hydroxy- synthetase/guanosine- a (2E)-hexadec-2-enoyl-[acp] CDP-diacylglycerol--serine SGR_RS05945 3-methyl-2- oxopentanoate decarboxylase: transferase: SGR_RS27705 HpnH: hpnH [+ 8 isozymes] kinase: argB SGR_RS12585 a (2E)-2- a [protein]-L- diphosphate a metal RS04725 a metal ketoacyl- phosphate kinase: ndk GDP SGR_RS15980 phosphate residue succinyltransferase (3S)-3-methyl-2- L-citrulline protein]-C-terminal- SGR_RS08170 terminal Gly-Gly] 3-amino-2,4- homoplatensic- 3',5'-bis(diphosphate) 3'- long-chain fatty O-phosphatidyltransferase: phosphopyruvate (S)-3- oxobutanoate SGR_RS23555 SGR_RS27020 [+ 2 isozymes] an N- a diacyl-sn enoyl-CoA methionine cation cation ACP synthase: pyrophosphokinase: synthase: NADPH repair (prokaryotes) subunit: SGR_RS10945 oxopentanoate ornithine 3',5'-ADP a holo [peptidyl- D-galactosamine γ-(5-phospho-L- myo-inositol a fatty acid ethylamine glyoxylate Peptide RS22225 Peptide dihydroxybenzoate CoA pyrophosphohydrolase: enoyl-ACP acid--CoA ligase: pssA hydratase: eno hydroxybutanoyl-CoA oxaloacetate a reduced a (2R)-2- an alkylated a DNA containing a uridylylated acetate acetoxyarylamine -glycerol synthase 3-hydroxyacyl-CoA SGR_RS07310 SGR_RS30080 2-O-(α-D- SGR_RS15985 a 3-sn-phosphatidyl- carbamoyltransferase: an acyl-CoA CO H + carrier protein] adenosyl hopane a halide anion 6-phosphate glutamyl)-L-glutamate 2-[2-O-(α-D- reductase SGR_RS17830 2 ferredoxin [iron- met an apurinic/ PII protein SGR_RS30080 glucopyranosyl) phosphopyruvate 3-hydroxyacyl-CoA 3-methylbutanoyl- argF 2-iminobutanoate ornithine undecaprenyl-diphospho-N- a [protein]-S- hydroxy fatty acid nucleobase II: fabF dehydrogenase: mannopyranosyl) FabI: fabI [+ 10 isozymes] L-serine NADPH UMP sulfur] cluster a thymine in DNA apyrimidinic site a metal a metal 2+ 2+ a thiocarboxylated bifunctional (p)ppGpp -3-phospho- α α hydratase: eno dehydrogenase: CoA carbamoyltransferase: acetylmuramoyl-L-alanyl-γ-D- methyl-L-cysteine RS18665 Ni RS03100 Ni SGR_RS06765 1-deoxy-D-xylulose -(1->2)-α-D- , -trehalose phosphatidylserine cation cation a 3-oxooctanoyl- [sulfur-carrier 3-amino-2,4- 3-oxo- synthetase/guanosine- D-glycerate Pentose Phosphate Pathways SGR_RS06765 isobutanoyl-CoA (2S)-2- L-ornithine argF glutamyl-L-lysyl- D-alanyl-D-alanine 5-phosphate glucopyranosyl]- 6-phosphate a palmitoyl-[acp] stearoyl-CoA decarboxylase: phosphoenolpyruvate isovaleryl-CoA [acp] protein with a C- dihydroxybenzoyl- homoplatensic- 3',5'-bis(diphosphate) 3'- methylbutanoyl-CoA 1-deoxy-D-xylulose- D-glycerate trehalose- SGR_RS05725 acetoacetyl-CoA dehydrogenase: ornithine- potassium- terminal Gly-Gly] CoA CoA pyrophosphohydrolase: pyruvate pentose phosphate pathway carbamoyl 3-oxoacyl- 5-phosphate phosphatase: an L-1- SGR_RS23680 -oxo-acid 2-oxobutanoate UDP-N-acetyl-α-D- a pentaglycine cross- lysine within 3-aci- a peptidoglycan 3-amino-4- D-sedoheptulose 6-O-trans- (4-octanoyl-5- cytidine phosphoenol a metal a metal K + transporting K + acetyl-CoA C- SGR_RS08440 kinase: pyk phosphate L-ornithine di-trans,octa-cis- a protein with methanethiol O-succinyl-L- isobutanal adenosylcobinamide a nucleoside ammonium NAD + H O L-cysteate RS10010 [acyl-carrier- 2-O-(α-D- otsB acetyl-CoA C- 3-methylcrotonyl- muramoyl-L-alanyl-γ-D- an octanoyl-[acp] dimer (generic) RNA 2 Ins(2)P 1-phosphate methoxy-mycolyl- oxo-2H-furan-3-yl) cation cation reductoisomerase: phosphatidylethanolamine (R)-NADPHX D-glucopyranose transaminase: L-histidine degradation II undecaprenyl phosphate bridge of peptidoglycan LAXTG motif gcv protein H nitropropanoate homoserine triphosphate hydroxybenzoate nucleoside pyruvate ATPase protein] acyltransferase: GDP glucopyranosyl) pyruvate bifunctional acyltransferase: CoA glutamyl-L-lysyl-D-alanine bifunctional arylamine N- bifunctional trehalose 6- methyl phosphate pyruvate SGR_RS08940 α α 6-phosphate methylacrylyl-CoA (E)-2- rocD glutamine- inositol butenolide deaminase: reductase: SGR_RS07225 -D-glycerate , -trehalose palmitate kinase: pyk ADP-dependent SGR_RS07225 adenosylcobinamide acetyltransferase: aspartate phosphate kinase: pyk an anion RS25510 an anion methylcrotonoyl-CoA acetyl/propionyl/ hydrolyzing acetaldehyde lytic murein nitrite monophosphatase: class II fructose- trehalose- phosphate SGR_RS17525 fabG 3-amino-2,4- MEP NAD(P)H-hydrate glucose-6- [+ 6 isozymes] enoyl-CoA L-glutamate-5- class E sortase: lipoyl(octanoyl) nitronate cystathionine kinase/ RNA polymerase: SGR_RS12585 transaminase/ pyruvate a metal a metal platensicyl-CoA pyruvate enoyl-CoA methylcrotonyl- carbamoyl- his phospho-N- dehydrogenase transglycosylase: reductase: SGR_RS05870 bisphosphate phosphatase: reductase RS05995 dihydroxybenzoylsulfanide long-chain fatty dehydratase/ phosphate hydratase: semialdehyde propanoyl-CoA SGR_RS18415 transferase monooxygenase: gamma- adenosylcobinamide- SGR_RS12700 arylamine N- aspartate 4- cytidine kinase: pyk cation cation 3-oxoacyl- hydratase: CoA carboxylase phosphate histidine acetylmuramoyl- (acetylating): SGR_RS27580 nirD nirB inositol aldolase: fbaA otsB [(3S,4R)-4-(octanoyl)BprA: bprA 2-C-methyl-D- acid--CoA ligase: NAD(P)H-hydrate dehydrogenase: acetyl-CoA SGR_RS05945 [+ 3 isozymes] LipB: lipB SGR_RS24895 synthase: phosphate [+ 3 isozymes] acetyltransferase: decarboxylase: trehalose- deaminase: allantoin RS05635 allantoin ACP SGR_RS05945 subunit alpha: synthase: ammonia- pentapeptide- [+ 3 isozymes] monophosphatase: -5-oxooxolan-3- pyruvate erythritol 4-phosphate SGR_RS17830 epimerase: SGR_RS27860 phosphate [+ 2 isozymes] SGR_RS12715 SGR_RS02680 guanylyltransferase: trans-methoxy- SGR_RS13065 reductase (S)-3-hydroxy- SGR_RS23690 carA carB lyase: hutH transferase: SGR_RS24815 SGR_RS08170 SGR_RS23555 yl]methyl phosphate cytidylyltransferase: [+ 10 isozymes] SGR_RS13770 6-phospho (2S,3S)-3-hydroxy-2- propionyltransferase: pta a protein with LAXT a [glycine-cleavage SGR_RS26610 3-acetylamino-4- mono-mycolate uridine a metal a metal FabG: fabG isobutanoyl-CoA urocanate SGR_RS27020 a peptide with an nitrite DHAP D-erythrose 3-sulfopyruvate hemin RS11145 hemin SGR_RS19905 (S)-NADPHX D-glucono- methylbutanoyl-CoA 3-methylglutaconyl- (S)-1-pyrroline- carbamate carboxyl end attached acyl-carrier protein complex H protein] [unspecified GlcNAc-1,6- adenosyl-cobinamide RNA hydroxybenzoate myo-inositol cation cation a (3R)-3- 3-hydroxyisobutyryl- propanoyl + a lipid II thioplatensimycin palmitoyl-CoA NADH repair (prokaryotes) CoA 5-carboxylate urocanate N-terminal glycine N 6 -octanoyl-L-lysine 3-oxopropanoate nitrite succinate isobutanoyl-CoA NADH H anhydro-MurNAc- RS01865 hydroxyoctanoyl- streptomycin biosynthesis 4-(cytidine 5'- glutaminyl-tRNA gln Aminoacyl-tRNA Charging 1,5-lactone to a pentaglycine cross- degradation met phosphate bifunctional CoA hydrolase: phosphate hydratase: undecaprenyl-diphospho-N UMP pentapeptide ala ala [acp] diphospho)-2-C- biosynthesis via transamidation 6-phosphogluconolactonase: SGR_RS05935 pyrroline-5- γ bridge of peptidoglycan products] Na + RS16360 Na + tRNA charging ADP-dependent SGR_RS22170 -acetylmuramoyl-L-alanyl- - beta-hydroxyacyl- myo-inositol methyl-D-erythritol NADH pgl carboxylate acetate kinase: a metal a metal 4-(cytidine 5'- NAD(P)H-hydrate (S)-3-hydroxy- 2-methylacetoacetyl-CoA D-glutamyl-L-lysyl- D-alanine RS22420 ACP glu D-gluconate reductase: SGR_RS10380 4-imidazolone- cation cation diphospho)- dehydratase/ isobutanoate HMG-CoA CO dehydratase: Trp proC 2 5-propanoate nitrate RS22750 nitrate platensimycin phe a tRNA Phe trp a tRNA NAD(P)H-hydrate 6-phosphate 6 SGR_RS16075 2-C-methyl-D- 3-hydroxyisobutyrate propanoate N -(3-methylbut- 3-[(1-carboxyvinyl) an [amino-group carrier protein]- an N 3 -methyladenine a dietary all- (S)-4-hydroxy- hydrogen D-sedoheptulose pro a tRNA Pro glu a tRNA glu elongator tRNA Met met initiator tRNA Met met cys a tRNA Cys lys a tRNA Lys val a tRNA Val leu a tRNA Leu gly a tRNA Gly ile a tRNA Ile tyr a tRNA Tyr thr a tRNA Thr his a tRNA His epimerase: decarboxylating 6- dehydrogenase: acetyl-CoA C- hydroxymethylglutaryl- imidazolonepropionase: a 5-L-glutamyl- a homogalacturonan γ a peptide with a NADP + FMNH an arylamine A(H2) L-threonine 3- digallate squalene erythritol kinase: pro a sulfurated [sulfur carrier] 2-en-1-yl)- an amino acid oxy]benzoate SAM C-terminal- -(L-glutamate 5- in DNA 2 trans-retinyl ester 2-oxopentanoate peroxide 1,7-bisphosphate purine cys a metal a metal beta-hydroxyacyl- ser asp Arg Ala acyltransferase: SGR_RS22185 37 [peptide] leader sequence RS23735 scyllo-inosose SGR_RS21645 gln ser a tRNA tRNA asp arg a tRNA a tRNA ala SGR_RS13770 phosphogluconate mmsB CoA lyase: adenosine in tRNA semialdehyde-2-yl)-L-glutamate arylamine N- O-phosphate tannase/feruloyl squalene- cation cation thiamine RS09110 thiamine ACP phenylalanine- asn tRNA Asn gln a tRNA Gln tryptophan-- (R)-NADHX SGR_RS07225 N-acetyl-gamma- threonine- 2-phospho-4-(cytidine dehydrogenase: gnd (S)-methylmalonate- SGR_RS23685 acetyltransferase: xanthine cystathionine esterase family -hopene dehydratase: an L-glutamyl- -tRNA proline-- glutamate-- tRNA ligase: trpS methionine-- methionine-- cysteine-- lysine-- valine-- leucine-- glycine-- isoleucine-- tyrosine-- threonine-- histidine-- bifunctional NADPH N-formimino- pectate lyase: glutamyl-phosphate DNA-3- flavin reductase: triacylglycerol 4-hydroxy-2- catalase/ class II fructose- phosphate 5'-diphospho)-2-C- NADP-dependent semialdehyde L-glutamate aminofutalosine SGR_RS24815 dehydrogenase beta-synthase: alpha/beta cyclase: [tRNA Gln ] imidazole ADP-dependent acetoacetate L-glutamate tRNA (N6-isopentenyl SGR_RS00975 reductase: argC signal lipase: oxovalerate peroxidase bisphosphate SGR_RS16070 methyl-D-erythritol ligase: pheS tRNA ligase: tRNA ligase: tryptophan-- serine--tRNA aspartate--tRNA tRNA ligase: tRNA ligase: tRNA ligase: arginine--tRNA tRNA ligase: tRNA ligase: tRNA ligase: tRNA ligase: tRNA ligase: tRNA ligase: tRNA ligase: tRNA ligase: alanine--tRNA degradation VI gamma- synthase methyladenine SGR_RS02900 molybdopterin decarboxylase: SGR_RS22120 hydrolase: shc glycerol NAD(P)H-hydrate phosphogluconate acetyl-CoA propanoyl-CoA adenosine(37)-C2)- peptidase I: lepB arylamine N- 2+ 2+ Asp-tRNA(Asn) SGR_RS29495 SGR_RS08915 SGR_RS09505 tRNA ligase: trpS ligase: serS ligase: aspS SGR_RS18770 SGR_RS18770 SGR_RS19940 ligase: argS SGR_RS20760 SGR_RS24550 SGR_RS24785 SGR_RS25020 SGR_RS27075 SGR_RS28315 SGR_RS29985 SGR_RS30100 ligase: alaS (to pyruvate) formimidoylglutamate glutamyltransferase: ggt MqnE: mqnE pectate lyase: N-acetyl-gamma- glycosylase I: [+ 2 isozymes] SGR_RS01155 aldolase: dmpG HPI: katG aldolase: fbaA (R)-1-amino-SGR_RS28125 Zn RS34980 Zn RS31890 a (2E)-oct- 2-C-methyl-D- phosphate dehydratase/ dehydrogenase: gndA CoA-acylating L-tryptophan methylthiotransferase [+ 4 isozymes] acetyltransferase: binding lanthionine SGR_RS05820 hop-22(29)-ene 1-amino-1-deoxy- /Glu-tRNA(Gln) deiminase: SGR_RS00985 glutamyl-phosphate SGR_RS11730 2-propanol O 2-enoyl-[acp] erythritol 2,4- synthase: NAD(P)H-hydrate D-ribulose methylmalonate- degradation I MiaB: miaB SGR_RS12585 subunit: xdhB gallate scyllo-inositol glu SGR_RS22180 α reductase: an N- D-erythrose -2-phosphate cyclodiphosphate amidotransferase: Phe Asn Gln Pro Glu Trp ser asp an L-methionyl- an L-methionyl- Cys Arg Lys Val Leu Gly Ile Tyr Thr His Ala semialdehyde an -(5-L- 6-amino-6- 8-hydroxypurine enoyl-ACP hisH hisF an L-phenylalanyl-[tRNA ] an L-asparaginyl-[tRNA ] an L-glutaminyl-[tRNA ] an L-prolyl-[tRNA ] an L-glutamyl-[tRNA ] an L-tryptophanyl-[tRNA ] an L-seryl-[tRNA ] an L-aspartyl-[tRNA ] an L-cysteinyl-[tRNA ] an L-arginyl-[tRNA ] an L-lysyl-[tRNA ] an L-valyl-[tRNA ] an L-leucyl-[tRNA ] a glycyl-[tRNA ] an L-isoleucyl-[tRNA ] an L-tyrosyl-[tRNA ] an L-threonyl-[tRNA ] an L-histidyl-[tRNA ] an L-alanyl-[tRNA ] epimerase: 5-phosphate (via anthranilate) + all-trans-retinol a fatty acid acetaldehyde pyruvate A H O DHAP gatB gatA gatC [elongator tRNA Met ] [initiator tRNA Met ] (S)-3-amino-2- N-formyl- met an unsaturated an [amino-group carrierSGR_RS29740 protein]- FMN NADPH H acetylarylamine 2 4-phosphate 2+ 2+ synthase: dehydrogenase: 6 glutamyl)- a peptide deoxyfutalosine a homogalacturonan an apurinic site Zn RS25015 Zn reductase a 5-phosphooxy- [+ 10 isozymes] SGR_RS13770 methylpropanoate N -(3-methylbut-2-en- pectate C-terminal-γ-(5-phospho- 3-methyladenine a leader sequence a peptide SGR_RS19910 (S)-NADHX ribulose- ribose-5- mmsA glycine cleavage trp L-glutamate 5'-deoxyadenosine an unsulfurated amino acid within DNA RS09610 FabI: fabI L-glutamyl- 1-yl)-2-(methylsulfanyl) met oligosaccharide L-glutamyl)-L-glutamate 1-amino-1-deoxy- ammonium tryptophan 2,3- N-formylglutamate 37 [sulfur carrier] 2-C-methyl-D-erythritol- Gln phosphate 3- phosphate adenosine in tRNA an octanoyl-[acp] scyllo-inositol [tRNA ] bifunctional a [glycine-cleavage dioxygenase: amidohydrolase: thr thr 2,4-cyclodiphosphate epimerase: isomerase: 6 (2S, 3S)-3- 4-phosphate ADP-dependent propanoyl-CoA complex H protein] N glycine cleavage system SGR_RS16905 RS20260 Asp-tRNA(Asn) rpe SGR_RS24480 N-Formyl-L- methylaspartate SGR_RS05305 serine serine beta- inosamine-phosphate flavodoxin- NAD(P)H-hydrate -[(R)-lipoyl]-L-lysine aminomethyltransferase a [2-oxoglutarate- dehypoxanthine an apo-[LYS2 L- β-D-fructofuranose an N-acyl-D- a [lipoyl-carrier an organic /Glu-tRNA(Gln) kynurenine a sulfurated coenzyme A 2-methylbutanoate + uroporphyrinogen-III carbamoyl + [DNA] tributyrin L(or D)-O- histidinol amidinotransferase: dependent dehydratase/ GcvT: gcvT glu dehydrogenase SAM 2-aminoadipyl- H hydrogencarbonate L-ornithine FMN NADH H glucosamine protein]-N 6 -[(R) gly RS18600 ketoacyl- D-xylulose D-ribose 5- glycine cleavage system kynurenine SAM futalosine 1-phosphate hypoxanthine hydroperoxide SGR_RS29605 (E)-4-hydroxy- amidotransferase: NAD(P)H-hydrate [sulfur carrier] 6 phosphate phosphoserine ACP 5-phosphate phosphate aminomethyltransferase aminomethyl- E2 protein] N - carrier-protein] uroporphyrinogen-III C- 6-phosphateputative N- DNA polymerase -dihydrolipoyl]- histidinol thioredoxin- 1-guanidino- 3-methylbut- gatB gatA gatC epimerase: formamidase: methyltransferase: cobA III subunit phosphoserine glycine thiol CydD thiol synthase GcvT: gcvT transferring octanoyl-L-lysine acetylmannosamine- L-lysine dihydrolipoyl xanthine dehydrogenase: dependent 1-deoxy-scyllo 2-enyl- Tetrapyrrole Biosynthesis SGR_RS13770 L-cysteine SGR_RS16895 dehypoxanthine holo-ACP acetate- carbonic flavin reductase: class II fructose- gamma and tau: triacylglycerol phosphatase oxidase II: fabF transketolase: dihydrolipoyl glycine mesaconate bifunctional ornithine 6-phosphate dehydrogenase: dehydrogenase hisD thiol -inositol 4- diphosphate an L-glutaminyl- degradation II lipoyl futalosine synthase: -CoA anhydrase: SGR_RS02900 bisphosphate SGR_RS19085 lipase: SerB: serB ThiO: thiO SGR_RS04460 dehydrogenase: dehydrogenase: L-kynurenine uroporphyrinogen-III carbamoyltransferase: 2-epimerase: lpdA molybdopterin peroxidase: a 3-oxodecanoyl- phosphate synthase: ispG Gln NADH synthase: cyclase: mqnC ligase: acs SGR_RS26990 [+ 2 isozymes] aldolase: fbaA SGR_RS01155 a [lipoyl-carrier RS32050 [tRNA ] tetrapyrrole biosynthesis [+ 3 isozymes] gcvP L-threonine degradation IV L-glutamine SGR_RS13775 C-methyltransferase/ argF α SGR_RS32150 [+ 10 isozymes] binding his bcp glyoxylate [acp] lpdA an N-acyl- -D- a 2'- 6 serine (E)-4-hydroxy-3- siroheme biosynthesis tetrapyrrole biosynthesis cys a [glycine-cleavage lipA [+ 3 isozymes] protein]-N -[(R subunit: xdhB RS22670 I (from glutamate) a [glycine-cleavage degradation II uroporphyrinogen-III mannosamine deoxyribonucleoside 6,8- an alcohol methylbut-2-en- complex H protein] N 6 - kynureninase: cyclic a holo-[LYS2 L- (2S)-2- )-lipoyl]-L-lysine 3-oxoacyl- II (from glycine) D-sedoheptulose D-glyceraldehyde cystathionine 6 synthase: SGR_RS20650 D-glyceraldehyde complex H protein] N kynU a [2-oxoglutarate 5'-deoxyadenosine dehypoxanthine 3',5'-ADP methylbutanoyl- diphosphate FMNH NAD + DHAP 6-phosphate 5'-monophosphate butanoate 1,2-dibutyrin dihydroxypurine [acyl-carrier- 1-guanidino- 1-yl diphosphate gamma-lyase: aminomethyldihydrolipoyl- (S)-citramalate thr an unsulfurated met 2-aminoadipyl- AMP 2 4-hydroxy-3- glu uroporphyrinogen-III 7-phosphate 3-phosphate -dihydrolipoyl-L-lysine gln 5'-deoxyadenosine met dehydrogenase futalosine CoA CO H O precorrin-2 L-citrulline protein] 1-deoxy- SGR_RS18125 L-lysine [sulfur carrier] carrier-protein] 2 2 RS18825 methylbut-2-enyl superpathway of L- Amino Acid Biosynthesis glutamate-- bifunctional gly 2-aminoprop- anthranilate glutamate E2 protein] N 6 reductase: scyllo-inositol superpathway of branched chain amino acid biosynthesis superpathway of L-serine diphosphate isoleucine biosynthesis I L-histidine biosynthesis L-arginine biosynthesis I (via L-ornithine) L-lysine biosynthesis I L-arginine biosynthesis II (acetyl cycle) L-arginine L-cysteine biosynthesis V (mycobacteria) tRNA ligase: uroporphyrinogen-III 5-aminolevulinate transaldolase: tal 2-enoate citramalate low specificity synthase large -lipoyl-L-lysine fabG reductase: and glycine biosynthesis I degradation I C-methyltransferase/ synthase: RS06320 an L-glutamyl-SGR_RS09505 synthase: hemA L-threonine subunit: gltB SGR_RS12175 (arginase pathway) uroporphyrinogen-III SGR_RS09735 3-oxoacyl- 4-hydroxy-3- oxaloacetate pyruvate O-phospho- Glu 5-aminolevulinate D-erythrose L-serine degradation aldolase: glu PRPP glu asp thr N-acetylglutamyl-phosphate 3-phospho-D-glycerate a [CysO sulfur- [tRNA ] F6P glycine cleavage system L-threonine a 7-aminomethyl-7- an [HPr]- phosphoenol 34 a thiocarboxylated 3-amino-4- 2251 D-glyceraldehyde IPP synthase: SGR_RS20650 a uridine an (R)-2- + guanosine ACP D-1-guanidino-1- methylbut-2-enyl bifunctional L-serine 4-phosphate SGR_RS32570 34 coenzyme A AsbD acyl- futalosine FMN NAD(P)H H D-alanyl-D-alanine enterobactin aspartate kinase: acetolactate phosphoglycerate arg carrier protein]- glutamyl-tRNA aminomethyltransferase degradation II deazaguanosine SAM L-histidine pyruvate in tRNA [SAMP] C- halocarboxylate a tRNA precursor hydroxybenzaldehyde in 23S rRNA GTP ATP 3-phosphate repressor LexA D-ala RS10025 reductase deoxy-3-dehydro- diphosphate aspartate ATP uroporphyrinogen-III C- porphobilinogen transketolase: 2-iminopropanoate L-arginine carrier protein D-alanyl- GTP amino-acid N- SGR_RS16690 threonine synthase amino-acid N- N-acetyl-gamma- dehydrogenase: thiocarboxylate reductase: ser GcvT: gcvT acetate pyruvate in tRNA terminal glycine arylamine N- 23S rRNA (5-formylfuran- FabG: fabG scyllo-inositol reductase: transaminase/ phosphoribosyltransferase: methyltransferase: cobA synthase: hemB SGR_RS04460 degradation D-alanine transcriptional enterochelin glycine isopentenyl- acetyltransferase: aspartate kinase: ammonia-lyase: large subunit: acetyltransferase: glutamyl-phosphate SGR_RS09820 SGR_RS20640 L-serine thr acetaldehyde acetyltransferase: (guanosine(2251) adenylate/guanylate adenylate/guanylate 3-yl)methyl diguanylate a (3R)-3- SGR_RS12175 aspartate 4- SGR_RS30445 precorrin-1 III (arginine gly phosphoenolpyruvate- HAD family futalosine FMN reductase: dipeptidase: repressor esterase: fes oxidase diphosphate SGR_RS20430 SGR_RS21110 SGR_RS12660 SGR_RS31020 SGR_RS20430 reductase: argC phosphoglycerate adenylyltransferase/ porphobilinogen [+ 3 isozymes] ammonia-lyase: L-threonine 3- S-adenosylmethionine:tRNA holo-ACP tRNA 2- SGR_RS24815 -2'-O)- cyclase domain- cyclase domain- phosphate cyclase: RS22920 hydroxydecanoyl- decarboxylase: 1-(5-phospho- L-ornithine (S)-4-amino-5- decarboxylase/ L-glutamate -protein hydrolase: ribonuclease Z: hydrolase: SGR_RS18845 SGR_RS30640 LexA: lexA ThiO: thiO Delta- bifunctional L-aspartyl-4-phosphate (2Z)-2-aminobut- dehydrogenase: sulfurtransferase bifunctional D-glyceraldehyde SGR_RS10070 dehydrogenase: acetaldehyde ribosyltransferase- synthase: thiouridine(34) arylamine N- methyltransferase containing protein: containing protein: synthase: N-(2,3- SGR_RS20110 [acp] SGR_RS23555 β-D-ribosyl)-ATP acetolactate bifunctional glutamate N-acetyl-gamma- oxopentanoate 2-aminoprop- agmatinase pathway) degradation I phosphotransferase: ptsP SGR_RS20580 SGR_RS24910 SGR_RS15705 [+ 2 isozymes] RS05100 beta-hydroxyacyl- D-1-guanidino- isomerase: idi glutamate N- 2-enoate acetylglutamate SGR_RS16040 MoeZ: moeZ uroporphyrinogen-III hydroxymethylbilane 3-phosphate pyruvate tdh dehydrogenase isomerase: SGR_RS28380 SGR_RS13775 synthase acetyltransferase: RlmB: rlmB SGR_RS12890 SGR_RS12890 D-ala SGR_RS32000 cleaved dihydroxybenzoyl) [+ 2 isozymes] pyruvate synthase: ilvN N-acetyltransferase/ glutamyl-phosphate ornithine- glutamate-1- 2-enoate L-glutamine L-2-amino-3- arg [+ 8 isozymes] 2-O- cyclic-GMP cyclic-AMP (5-formylfuran- 3-amino- asp phosphoribosyl- a [CysO sulfur- L-glutamate (acetylating): MnmA: mnmA SGR_RS12585 2251 repressor LexA -L-serine c-di-GMP ACP acetyltransferase/ aspartate- SGR_RS09835 amino-acid kinase: SGR_RS17235 reductase: 3-phosphooxypyruvate -oxo-acid C-methyltransferase/ synthase: hemC degradation I an [HPr protein]- methylguanosine 3-yl)methyl 1,3-dideoxy- ATP L-isoleucine a [CysO sulfur- carrier protein]- semialdehyde oxobutanoate degradation IX (via SGR_RS02680 glu dehypoxanthine 3-acetylamino-4- dehydratase: amino-acid semialdehyde acetyltransferase acetylglutamate SGR_RS29740 transaminase: uroporphyrinogen-III 34 π pyruvate a holo-[AsbD acyl- a single-stranded FMNH NAD(P) + in 23S rRNA phosphate biosynthesis IV carrier protein]- 2,1- an epoxyqueuosine N -phospho- 3',5'-ADP 34 2 hydroxybenzaldehyde SGR_RS16075 scyllo-inositol DMAPP aspartate kinase: diphosphatase: acetyltransferase (S)-2-acetolactate phosphoserine Gly-NH-CH - synthase: SGR_RS20650 preuroporphyrinogen glycine C- 4-aminobutanoate) NAD-glutamate carrier protein] a [SAMP] C- a 2-thiouridine an (S)-2- mature tRNA oligoribonucleotide futalosine hypoxanthine RS23020 dehydrogenase: ArgJ: argJ kinase: argB rocD Gly-Gly-adenylate 2 aminomutase: gln agmatine acetyl-CoA adenine met in tRNA L-histidine a halide anion SGR_RS16690 SGR_RS30440 ArgJ: argJ 2-iminobutanoate glu transaminase: serC C(O)-S-L-cysteine acetyltransferase: dehydrogenase: terminal glycine in tRNA hydroxycarboxylate RS19635 beta-hydroxyacyl- SGR_RS16685 N-acetyl-L-glutamate N-acetyl-L-glutamate 5-semialdehyde propanoate L-glutamate-5- hemL uroporphyrinogen-III C- 2-iminopropanoate imidazole glycerol glu tunicamycin biosynthesis aspartate kinase: 1-(5-phospho-β- ketol-acid bifunctional L-asparagine SGR_RS07060 SGR_RS22555 ACP N-acetyl-L- aspartate- long-chain fatty semialdehyde methyltransferase: cobA phosphate agmatinase: glutamate 2-oxoglutarate D-glucopyranose SGR_RS21110 D-ribosyl)-AMP reductoisomerase: acetylornithine O-phospho-L-serine uroporphyrinogen-III degradation I dehydratase: 1 semialdehyde 5-aminolevulinate synthase: hisH hisF N -amidinostreptamine 6-phosphate UDP-N-acetyl- glutamate ilvC gln acid--CoA ligase: precorrin-2 C-methyltransferase/ gly speB decarboxylase: phosphoribosyl- transaminase: L-glutamate adenylyltransferase/ 2503 an [amino-group carrier SGR_RS16070 6-phosphate α-D-glucosamine L-aspartyl- dehydrogenase: (2R)-2,3- SGR_RS17830 uroporphyrinogen- [+ 10 isozymes] SGR_RS20235 adenine a single an (S)-2- a peptide with an L-aspartyl- an L-glutamyl- (S)-1-pyrroline- alpha-D-glucose AMP acetylglutamate SGR_RS29755 gamma- sulfurtransferase porphobilinogen asn L-alanine coenzyme A an apo-[aryl- isobutanoate coenzyme A 2-oxoglutarate ectoine canavaninosuccinate protein]-C-terminal-γ- MeOH an unfolded 1 UTP 4-phosphate SGR_RS24340 dihydroxy-3- bifunctional glutamate phosphoserine glu putrescine 4-aminobutanoate in 23S rRNA stranded DNA halocarboxylate VibB an N-terminal Asn Gln his 5-carboxylate L-ornithine a (2E)-dec- dTDP-β-L- L-arginine:N - phosphate-specific kinase: 2-oxobutanoate glutamine-hydrolyzing [+ 10 isozymes] semialdehyde precorrin-2 III synthase: carrier protein] [tRNA ] [tRNA ] protein RS23055 RS05250 cyclohydrolase: methylbutanoate N-acetyltransferase/ propanoyl-CoA phosphatase SerB: serB MoeZ: moeZ synthase: hemB asparaginase: pyruvate degradation IV Xaa-L-proline (L-ornithyl)-L-glutamate Asp-tRNA(Asn) Asp-tRNA(Asn) L-glutamate catalase/ chaperonin 2-enoyl-[acp] rhamnose amidinostreptamine phosphoglucomutase: nucleoside triphosphate aspartate- SGR_RS17235 L-aspartate 4- carbamoyl-phosphate dehydrogenase: [CysO sulfur- dehydrogenase: cobA SGR_RS20650 acetylornithine L-histidine N(alpha) ornithine hisI acetolactate amino-acid SGR_RS19730 /Glu-tRNA(Gln) /Glu-tRNA(Gln) gamma- peroxidase GroEL: groL amidinotransferase: SGR_RS33600 pyrophosphohydrolase: β semialdehyde dihydroxy-acid synthase: carA carB carrier protein] 23S rRNA exodeoxyribonuclease HAD family ectoine transaminase: enoyl-ACP UDP-6-deoxy-5,6-ene- semialdehyde 1-(5-phospho- -D-ribosyl)- acetylglutamate acetyltransferase 2-oxoacid:ferredoxin ser pruA porphobilinogen uroporphyrinogen- holo-ACP acetate--CoA holo-ACP argininosuccinate -methyltransferase: semialdehyde cyclodeaminase: HPI: katG SGR_RS29605 synthase dehydratase: sirohydrochlorin asp ala VII: SGR_RS12185 leucyl hydroxylase: amidotransferase: amidotransferase: chaperonin reductase [+ 2 isozymes] N-acetyl-D-glucosamine SGR_RS22025 dehydrogenase: 5-[(5-phosphoribosylamino) kinase: argB 4-hydroxy- L-ornithine ArgJ: argJ oxidoreductase III synthase: (adenine(2503)-C(2) synthase: ligase: acs hydrolase: synthase: lyase: argH SGR_RS29755 egtD dehydrogenase: SGR_RS07940 [+ 3 isozymes] large subunit: ilvD carbamoyl phosphate alanine SGR_RS12190 aminopeptidase: thpD an [amino-group carrier gatB gatA gatC gatB gatA gatC GroEL: groL FabI: fabI dTDP-L- streptidine α-D- UMP SGR_RS16685 methylideneamino]imidazole- tetrahydrodipicolinate subunit beta: serine glu hydroxymethylbilane SGR_RS22755 )-methyltransferase SGR_RS13775 SGR_RS20580 SGR_RS13775 an L-asparaginyl- an L-glutaminyl- pruA N-acetylglutamyl- SGR_RS31020 3-methyl-2- sirohydrochlorin dehydrogenase: ald SGR_RS26585 protein]-C-terminal-γ-(L- hercynine pro formaldehyde a protein RS19925 dihydrostreptose 6-phosphate glucopyranose aspartate- 4-carboxamide synthase: dapA SGR_RS14495 hydroxymethyltransferase: synthase: hemC RlmN: rlmN [+ 8 isozymes] [tRNA Asn ] [tRNA Gln ] RS12455 a decanoyl-[acyl- 5'-nucleotidase: phosphate acetolactate oxobutanoate N-acetyl-L-ornithine chelatase: SGR_RS25230 uroporphyrinogen-III pyruvate glutamate 5-semialdehyde- glu 1-phosphate UDP-N- semialdehyde bifunctional 1-(5- SGR_RS10065 a single-stranded carrier protein] SGR_RS32860 4-hydroxy- synthase: ilvN preuroporphyrinogen sirohydrochlorin a ribonucleoside a holo-[aryl- isobutanoyl-CoA diphosphate a holo-[VibB aryl- a peptide with 5-hydroxyectoine succinate L-canavanine fumarate 2-yl)-L-glutamate holomycin biosynthesis N-acetyl- 2-oxobutanoate Amine and Polyamine Degradation 2503 3',5'-ADP AMP 3',5'-ADP dTDP-dihydrostreptose-- acetylgalactosamine- dehydrogenase: phosphoribosyl)-5-((5- tetrahydrodipicolinate [+ 2 isozymes] uracil degradation chelatase: SGR_RS06850 a 2-methyladenine 5'-monophosphate oligodeoxyribonucleotide carrier protein] an (S)-2- carrier protein] a proteinogenic beta- uridine gamma- SGR_RS09835 isopropylmalate branched-chain 5'-deoxyadenosine met a halide anion an N-terminal streptidine-6-phosphate 5,6-ene SGR_RS24340 phosphoribosylamino) synthase: dapA I (reductive) bifunctional Secondary Metabolite Degradation in 23S rRNA hydroxycarboxylate amino acid ketoacyl- glutamyl- (S)-2-aceto-2- synthase: amino acid ornithine acetolactate siroheme L-proline RS33010 dihydrostreptosyltransferase: strH CDP-α-D-glucose methylideneamino)imidazole- (2S,4S)-4- gly L-methionine biosynthesis III uroporphyrinogen-III superpathway of N-acetylglucosamine, ACP cys L-aspartate 4- phosphate hydroxybutanoate SGR_RS17215 aminotransferase: carbamoyltransferase: synthase uracil allantoin degradation superpathway of semialdehyde 4- carboxamide isomerase/ hydroxy-2,3,4,5- argF large subunit: C-methyltransferase/ N-acetylmannosamine and N- allantoin degradation anhydromuropeptides recycling I RS00925 synthase O-1,4-α-L- phosphoribosylanthranilate reductase: tetrahydrodipicolinate ketol-acid 2-isopropylmalate SGR_RS09750 glycine to ureidoglycolate II 4-aminobutanoate to ureidoglycolate SGR_RS31020 uroporphyrinogen- acetylneuraminate degradation an 1-acyl-2- a [protein]-S- a uridine 34 a [protein] N-terminal- a [release factor]- an [RNA]-3'- II: fabF dihydrostreptosyl- UDP-N-acetyl- homoserine isomerase PriA: priA argC dihydrodipicolinate reductoisomerase: synthase: leuA biosynthesis IV L-homoserine (ammonia producing) degradation I (urea producing) GlcNAc-1,6- Reactive Blue 5 a proteinogenic leukotriene-C4 CDP-choline 5-aminolevulinate succinate a sphingomyelin D-glucopyranose DNA with lesion long chain ethanol III synthase: N-acetylneuraminate arachidonoyl- sulfanyl-L-cysteine in tRNA formyl-L-methionine L-glutamine ribonucleoside- L-homocysteine cys a protein a 3- streptidine CDP-N-methyl- tunicaminyl-uracil dehydrogenase: N-acetyl- reductase: ilvC acetolactate 5,6-dihydrouracil anhMurNAc- amino acid polyphosphate phosphoribulosylformimino- val homoserine O- SGR_RS20650 (S)-(+)-allantoin 4-aminobutanoate (S)-(+)-allantoin sn-glycerol peptide chain 2',3'- glucose 1- excinuclease polyphosphate catalase/ RS33070 oxododecanoyl- 6-phosphate L-glucosamine an L-cysteinyl-[HlmE SGR_RS10725 gamma-glutamyl- SGR_RS02240 (R)-2,3-dihydroxy- (2S)-2- thr synthase: ilvN L-Ala-γ-D-Glu- homocysteine S- cysteine AICAR-phosphate acetyltransferase: allantoinase 4-aminobutyrate- allantoinase release factor cyclophosphate dehydrogenase: ABC subunit kinase 2: ppk2 peroxidase endopeptidase [acp] non-ribosomal phosphate 3-methylpentanoate isopropylmalate low specificity SGR_RS09835 dihydropyrimidinase: uroporphyrinogen- N-acetyl-D- DAP-D-Ala Dyp-type tRNA 2- ADP-forming peptide sphingomyelin RNA 2',3'-cyclic methyltransferase: dioxygenase: L-homoserine 4-hydroxy- superpathway SGR_RS33220 AllB: allB -2-oxoglutarate AllB: allB chloramphenicol acyl--CoA ligase: N(5)-glutamine SGR_RS00240 UvrA: polyphosphate HPI: katG La: lon 3-oxoacyl- peptide synthetase] reductase: 3-isopropylmalate L-citrulline L-threonine (S)-2-aceto-2- hydA III synthase: mannosamine peroxidase: gamma- thiouridine(34) succinate--CoA deformylase: def phosphodiesterase: phosphodiesterase: mmuM SGR_RS08520 SecY [acyl-carrier- N-acetyl- imidazole tetrahydrodipicolinate dihydroxy-acid of L-threonine SGR_RS22755 allantoate transaminase: allantoate phosphotransferase SGR_RS21205 methyltransferase: [+ 2 isozymes] SGR_RS23765 kinase 2: ppk2 [+ 3 isozymes] SGR_RS29740 dehydratase: aldolase: hydroxybutanoate O-acetyl-L- SGR_RS35275 glutamyltransferase: ggt synthase ligase: sucD sucC peptide sph an [RNA]-3'-thpR D-glucono- protein] tunicaminyl-uracil homoserine glycerol reductase: dehydratase: biosynthesis 3-ureidopropanoate gabT CPT: cpt prmC met 3-sulfino-L-alanine [+ 3 isozymes] long chain acetaldehyde a peptide N-acetyl-L- leuD leuC argininosuccinate SGR_RS32570 2-aceto-2-hydroxy- homoserine hydrogen sulfide succinate [+ 2 isozymes] MnmA: mnmA deformylase: def a [release factor]-N 5 ribunucleoside- DNA without dihydrostreptomycin kinase: SGR_RS08730 ilvD uroporphyrinogen-III allantoate allantoicase: alc 1,5-lactone polyphosphate RS20345 reductase: phosphate glutamate 5- oxaloacetate synthase: argG gly butanoate semialdehyde N-acetyl-β-D- L-alanyl-γ-D- a 1-acyl-2- 5-aminolevulinyl- -methyl-L-glutamine 2'-phosphate lesion 6-phosphate a (2E)-2-amino-3- SGR_RS10715 (3S)-3-methyl-2- β-ureidopropionase: N-acetyl-D- amidohydrolase: α γ CMP fabG synthase: semialdehyde (S)-2,3,4,5- 2-isopropylmaleate bifunctional argininosuccinate succinate- allantoicase: alc an -( -L-glutamyl) diphosphate ADP phosphate succinyl-CoA a ceramide phosphocholine sulfanylprop-2-enoyl- isomeroreductase: O-acetylhomoserine SGR_RS06015 mannosamine SGR_RS22175 glucosamine-1,6- glutamyl-meso-2,6- 3-[(4-amino-6-chloro- leukotriene-D4 arachidonoyl- AMP CoA a [protein]- a 2-thiouridine 34 N-acetyl-D- O-phospho- hisH hisF acetylornithine tetrahydrodipicolinate oxopentanoate aspartate synthase: 2,2'-disulfonyl -L-amino acid an N-terminal L- 3-oxoacyl- [HlmE non-ribosomal 3-isopropylmalate ilvC sulfhydrylase: 6-phosphate semialdehyde anhydro-N-acetyl- diaminopimeloyl- 1,3,5-triazin-2-yl) phthalate phosphatidylcholine L-cysteine in tRNA formate MreD glucosaminyl-N-acetyl- L-homoserine hydrogencarbonate transaminase: 2,3,4,5- branched-chain transaminase/ SGR_RS29770 (S)-ureidoglycine (S)-ureidoglycolate azobenzene methionyl-[protein] ACP dehydratase: (R)-2,3-dihydroxy- SGR_RS33225 β putative N- dehydrogenase β-D-muramate D-alanine amino]benzenesulfonate peptide synthetase] D-erythro-1- tetrahydropyridine- amino acid aspartate 4- -alanine RS20465 reductase pro tunicaminyl-uracil threonine AICAR glutamine- SGR_RS29755 leuD leuC 3-methylpentanoate acetylmannosamine- (NADP(+)): beta-N- streptomycin (imidazol-4- 2,6-dicarboxylate N- aminotransferase: decarboxylase: L-arginino-succinate FabG: fabG 6-phosphate synthase: hydrolyzing N-acetyl-L- 6-phosphate SGR_RS13575 acetylhexosaminidase: a (3R)-3- yl)-glycerol succinyltransferase: SGR_RS09750 (2R,3S)-3- SGR_RS23555 dihydroxy-acid putrescine degradation I a 1-acyl,2-oleoyl- (S)-5-amino-3- a single- a 3,5,7,9,11,13,15- a uracil 1498 6,8- 6-O-cis-methoxy- SGR_RS12115 carbamoyl- ornithine isopropylmalate argininosuccinate L-homocysteine 2-epimerase: putrescine degradation IV SGR_RS22830 L-alanyl-γ-D- tyr SAM ARP a proteinogenic glutathione CDP-choline coenzyme A [EntB aryl- acetyl-CoA fumarate asp 3'-ketolactose a holo [PedN acyl- hepta-oxo- D-glucopyranose a uridine in tRNA mycolyl-trehalose crotonyl-CoA hydroxydodecanoyl- streptomycin streptomycin-6- a (2E)-2-[(2E)-2- 3-phosphate dapD dehydratase: ilvD succinate sn-glycerol oxohexanoate stranded RNA in 16S rRNA dihydroxypurine cys urea RS04100 urea N-acetyl-D-glucosaminyl- [+ 2 isozymes] imidazoleglycerol- phosphate asp lyase: argH SGR_RS32150 urea beta-N- glutamyl-meso- amino acid carrier protein] carrier protein] hexadecanoyl-[PKS-acp] 16S rRNA glucose 1- tRNA xanthine 6-phosphate crotonyl-CoA [acp] 6-kinase: phosphatase: azanidyl-3-sulfanylprop- ile 3-isopropylmalate (3S)-3-methyl-2- (S)-ureidoglycolate ACP S- aldo/keto an L-prolyl- tunicaminyl-uracil phosphate synthase: N-succinyl-2-amino- methionine N-acetyl-D- putrescine putrescine degradation II acetylglucosaminidase diaminopimelate (uracil(1498)-N(3))- dehydrogenase: dihydrouridine dehydrogenase trehalose- carboxylase/ cystathionine SecD beta-hydroxyacyl- SGR_RS29600 SGR_RS29630 2-enamido]-3-[HlmE dehydrogenase: L-tryptophan biosynthesis oxopentanoate 5-methyltetrahydropteroyltriglutamate- beta-glucosidase: malonyltransferase: reductase: [RedO prolyl- thr dehydratase carA carB 6-ketopimelate aspartate kinase: synthase: glucosamine domain-containing chloramphenicol holo-ACP 3-keto-5- polyribonucleotide L-aspartate methyltransferase: SGR_RS35355 synthase molybdopterin phosphatase: reductase: beta-synthase: ACP non-ribosomal SGR_RS09755 arg - homocysteine S- bifunctional FO SGR_RS01745 fabD SGR_RS19330 carrier protein] HisB: hisB succinyldiaminopimelate SGR_RS16690 branched-chain metH 6-phosphate urea protein: SGR_RS24290 gamma- phosphotransferase synthase: aminohexanoate nucleotidyltransferase: oxidase: SGR_RS24900 [+ 2 isozymes] DusB: dusB binding otsB ccrA SGR_RS22120 dehydratase: streptomycin peptide synthetase] carbamoyl (2S)-2-isopropyl- methyltransferase: metE biosynthesis protein [+ 5 isozymes] [+ 2 isozymes] [+ 17 isozymes] an N 3 - trehalose- threonine 3-(imidazol-4- L-ornithine transaminase: dapC aspartate kinase: gln amino acid methionine N-acetylglucosamine- 4-aminobutanal urease: glutamyltransferase: ggt CPT: cpt SGR_RS13775 cleavage protein: SGR_RS08740 SGR_RS20400 a malonyl[PedN 9-hydroxy-3,5,7,11,13,15- D-glucono- a 5,6-dihydrouridine subunit: xdhB (2S)- RS06845 SGR_RS16075 phosphate 3-oxosuccinate chorismate 1,6-anhydro-N- CofGH: SGR_RS21035 methyluracil 1498 cis-methoxy- ser ammonia-lyase: yl)-2-oxopropyl SGR_RS21110 aminotransferase: synthase: [+ 2 isozymes] 6-phosphate SGR_RS01080 SGR_RS33240 acyl-carrier hexaoxohexadecanoyl- 1,5-lactone in tRNA ethylmalonyl-CoA a tunicamycin N-succinyl-L,L-2,6- acetyl-β-muramate β in 16S rRNA urate mono-mycolate beta-hydroxyacyl- SGR_RS12660 phosphate SGR_RS09750 SGR_RS09940 deacetylase: nagA 4-aminobutanal gamma- 4-aminobutanoate ureB a 1-acyl-2-oleoyl- CMP a single- 3-keto- -D- protein] [PKS-acp] RS33515 a 1H-pyrrole- ornithine diaminopimelate L-aspartyl- an α-(γ-L-glutamyl) a holo-[EntB aryl- a nucleoside 2-iminosuccinate succinate D-glucopyranose ACP IM-2 type γ- 4-amino-2- (2Z)-2-aminobut- histidinol- anthranilate D-glucosamine aminobutyraldehyde degradation III SGR_RS01085 D-glucarate 5-amino-5-(4-hydroxybenzyl)-6- L-cysteinylglycine sn-glycero-3- 3',5'-ADP stranded RNA galactose 2-carbonyl- carbamoyltransferase: succinyl- 4-phosphate 5'-deoxyadenosine 2-iminoacetate met -L-amino acid carrier protein] (S)-3- diphosphate dehydratase: butyrolactones (methanethioyl)-5-oxo- 2-enoate phosphate 4-methyl-2- synthase component ile met ammonia assimilation cycle III 6-phosphate dehydrogenase: degradation I (D-ribitylimino)-5,6-dihydrouracil phosphocholine acetoacetate [RedO prolyl- argF diaminopimelate L-proline gamma- 4-aminobutanoate [+ 2 isozymes] aminobutanoyl-CoA SGR_RS16070 biosynthesis 3-sulfanylpyrrolidine- transaminase: oxopentanoate aspartate- I: SGR_RS27255 SGR_RS09015 ammonium N-acetyl-D- carrier protein] desuccinylase: biosynthesis I aminobutyraldehyde 4-aminobutyrate- muramate 6- RS06870 a (2E)-dodec- 2-carboxyl-[HlmE hisC semialdehyde gamma- D-glucarate DHAP SGR_RS11750 (from L-glutamate) branched-chain ammonium dehydrogenase: -2-oxoglutarate phosphate RS13010 non-ribosomal dehydrogenase: superpathway of L-cysteine glucarate UDP-N-acetyl- decaprenyl-diphospho-N- RNase III mRNA a 1-(1-alkenyl) N-acetyl-β- 527 6-O-trans-keto- 2-enoyl-[acp] malonyl-CoA 2-oxo-3- A-factor γ- histidinol- asp L-citrulline amino acid anthranilate PRPP α-D-glucosamine SGR_RS09015 1-pyrroline aminobutyraldehyde 1,2-dipalmitoyl- [EntF L-seryl- a holo [PedD acyl- a guanine a [protein] (L-serine/L- peptide synthetase] geosmin biosynthesis SGR_RS16685 biosynthesis (mammalian) transaminase: N-acetylmuramic dehydratase: α-D-glucosamine acetylmuramoyl-pentapeptide glutathione CDP-choline coenzyme A processing -sn-glycero-3- 3-phenylpropanoate neuraminate CTP 3-oxopropanoate D-ala roseoflavin mycolyl-trehalose CAIR trp enoyl-ACP (phosphooxy) butyrolactone 2-iminobutanoate phosphate L,L-diaminopimelate glu aminotransferase: 2-oxoglutarate glu 6-phosphate dehydrogenase: hypoglycin A sn-glycerol carrier protein] carrier protein] in 16S rRNA threonine) phosphate a [RedX acyl- NADP-specific gamma- gabT acid 6- SGR_RS28995 substrate phosphocholine 16S rRNA malonic bifunctional 6-phosphate 5-(carboxyamino) reductase propyl 3- biosynthesis transaminase: glutamate SGR_RS09750 aspartate- glutamine SGR_RS09050 succinate 5-dehydro-4- bifunctional 3- ACP S- protein carrier protein]- (2E,6E)-farnesyl anthranilate L-cysteine biosynthesis I glutamate glucosamine- aminobutyraldehyde phosphate (guanine(527)-N(7) semialdehyde D-alanine--D- riboflavin kinase/ trehalose- imidazole tryptophan 7- FabI: fabI oxoalkanoate SGR_RS27185 argininosuccinate diaminopimelate 5-kinase: semialdehyde met synthetase: semialdehyde deoxy-D-glucarate undecaprenyldiphospho- chloramphenicol phenylpropionate/ N-acylneuraminate malonyltransferase: phosphatase: (1H-pyrrole- DHAP diphosphate phosphoribosyltransferase: trpD dehydrogenase: gdhA 6-phosphate dehydrogenase: 4-aminobutanoate etherase: murQ holo-ACP )-methyltransferase reductase: alanine ligase: FAD synthetase: phosphatase: ribonucleotide halogenase: RS25185 synthase: 4-amino-2- germacradienol/ synthase: argG epimerase: γ-L-glutamylSGR_RS24710 leu dehydrogenase: SGR_RS32350 N-acetyl-D- muramoylpentapeptide beta-N- phosphotransferase cinnamic acid cytidylyltransferase: fabD SGR_RS34270 RS11425 2-carbonyl) 2-oxo-3- L-histidinol methionine deaminase: SGR_RS09050 gamma- synthase: ribonuclease III: lysoplasmalogenase: RsmG: rsmG SGR_RS12195 SGR_RS09425 SGR_RS08855 otsB mutase: purE SGR_RS30910 a dodecanoyl-[acp] a malonyl-[RedN] SGR_RS34400 (methanethioyl)-5-oxo- geosmin argininosuccinate SGR_RS08445 SGR_RS24340 ser glutamate synthase [+ 2 isozymes] acetylglucosaminyltransferase: dioxygenase SGR_RS13115 [+ 2 isozymes] an N 7 - [+ 2 isozymes] trehalose- malonyl-CoA -L-cysteine a 2-oxo-3- (phosphonooxy) 2-oxobutanoate phosphate 5-phosphate nagB glucosamine glutamyltransferase: ggt CPT: cpt SGR_RS13775 SGR_RS09360 SGR_RS28270 a malonyl- roseoflavin 7-chloro-L- synthase: synthase: adenosyltransferase: large subunit: gltB murG ferredoxin subunit: 527 3-hydroxypropanoate D-alanyl-D-alanine trans-keto- AIR (phosphooxy)propyl propyl 8-methyl- 3-sulfanylpyrrolidine- glutamate-5- L-asparagine L-aspartate 4- N-(5-phosphoribosyl)-anthranilate 6-phosphate [PedD acyl- methylguanine a [protein] Ser/Thr 5'-phosphate tryptophan 2-carboxylate (1E,4S,5E,7R)-SGR_RS34160 histidinol- SGR_RS29770 meso-diaminopimelate SGR_RS30260 serine F6P 4-aminobutanoate succinate tartronate SGR_RS27915 CMP-N-acetyl- in 16S rRNA mono-mycolate 3-oxoalkanoate 3-oxononanoate acetolactate semialdehyde biosynthesis I semialdehyde N-acetylglucosamine- 1,2-dipalmitoyl- CMP a holo-[EntF 3-(5,6-dihydroxycyclohexa- carrier protein] lantibiotic germacra-1(10) phosphatase: bifunctional 1-(5- acetyltransferase: imidazole glycerol semialdehyde decaprenyl-pyrophosphoryl- RNase III sn-glycero-3- β-neuraminate synthase: synthase dehydrogenase: homoserine SAM ammonium gln 6-phosphate UDP hypoglycin B L-cysteinylglycine sn-glycero-3- 3',5'-ADP L-seryl-carrier an mRNA fragment a fatty aldehyde 1,3-dien-1-yl)propanoate RS21465 biosynthesis ,5-dien-11-ol hisN diaminopimelate phosphoribosyl)-5-((5- SGR_RS33220 phosphate 2-hydroxy-3- (N-acetylglucosamine)-N- processing phosphocholine RS25435 a malonyl-[RedL a dodecanoyl- a 3-oxo-3-(1H SGR_RS34400 large subunit: L-arginino- SGR_RS24720 L-phenylalanine asp dehydrogenase: deacetylase: nagA phosphocholine protein] 2-oxo-3-(phosphooxy) protein: germacradienol/ L-tyrosine decarboxylase: phosphoribosylamino) synthase: hisH hisF oxopropionate acetylmuramyl-(pentapeptide) product mRNA polyketide [RedQ acyl- -pyrrol-2-yl) a (4-alkanoyl-5- SGR_RS31020 histidinol succinate biosynthesis I asparagine SGR_RS10725 D-glucosamine propyl 8-methyl- SGR_RS21920 geosmin biosynthesis I SGR_RS03715 L-glutamate-5- methylideneamino)imidazole- O-acetyl-L-serine hydrogen sulfide reductase: synthase] carrier protein] propanoyl-[RedN] oxo-2H-furan-3-yl) (5E)-3-amino- acetolactate argininosuccinate synthase [+ 10 isozymes] 6-phosphate 3-oxononanoate synthase: histidinol [+ 2 isozymes] semialdehyde chorismate 4- carboxamide isomerase/ Nucleoside and Nucleotide Degradation SGR_RS06460 4-sulfanyl-5- synthase: ilvN (glutamine- L-homoserine a [glycine-cleavage all-trans- 10 966 6-O-α-mycolyl- methyl phosphate SGR_RS34160 dehydrogenase: lyase: argH chorismate phosphoribosylanthranilate phosphoglucosamine a 1-arachidonoyl- a 1-palmitoyl-2- a peptidoglycan an N - 7,8-dihydroneopterin a holo [BryP acyl- a guanine (2S)- a [protein]-L- a [protein]- butenolide (sulfanylmethylidene) SGR_RS09835 chorismate hydrolyzing) a sulfurated [sulfur carrier] SAM complex H protein] CDP-choline CDP-choline octaprenyl coenzyme A (S)-5-hydroxyisourate precorrin-6B ω trehalose 6- ser RS11640 (8S,9S,10S)- hisD chorismate lys isomerase PriA: priA SAH cysteine synthase: superpathway of pyrimidine mutase: SGR_RS13830 D-glycerate 2-acyl-sn-glycerol acyl-sn-glycerol 4-hydroxybenzoate formyltetrahydrofolate 2',3'-cyclic phosphate carrier protein] in 16S rRNA ethylmalonyl-CoA proline ( = 180) L-histidine pyrrolidin-2-one mutase: : asnB homoserine purine nucleotides degradation II (aerobic) N 6 -octanoyl-L-lysine diphosphate 16S rRNA precorrin-6y C5,15- peptidylprolyl phosphate RS25760 4-hydroxy- phosphate 8,10-dimethyl- (S)-2-aceto-2- arg SGR_RS23035 glu superpathway of purine deoxyribonucleosides degradation α polyprenol ACP S- methylmalonyl- histidine kinase: a 3-oxotetradecanoyl- [4-(6-methylheptanoyl) mutase: SGR_RS13560 asn kinase: 1-(2-carboxyphenylamino)-1- deoxyribonucleosides degradation -D-glucosamine glycerate kinase: (guanine(966)-N(2) hydroxyisourate methyltransferase isomerase: trehalose- L-serine 2,2'-bipyrrole- reductase 1-octalin hydroxybutanoate histidinal bifunctional o- chloramphenicol lysozyme: phosphomannose- malonyltransferase: CoA SGR_RS21785 [RedL polyketide -5-oxo-2H-furan-3- SGR_RS13560 (S)-1-pyrroline- [+ 2 isozymes] SGR_RS10715 deoxy-D-ribulose 5-phosphate adenosylhomocysteinase: 1-phosphate SGR_RS25505 chloramphenicol CoA pyrophosphatase: formyltetrahydrofolate )-methyltransferase hydrolase: uraH (decarboxylating) SGR_RS18395 phosphatase: ammonia-lyase: 5-methanol BprA: bprA germacradienol/ ketol-acid acetylhomoserine/ 2'-deoxycytidine phosphotransferase SGR_RS23985 4-hydroxybenzoate dependent alpha 1,6 fabD epimerase: mce [+ 5 isozymes] synthase] a [(3S,4R)-4-alkanoyl- yl]methyl phosphate histidinol [+ 2 isozymes] 5-carboxylate prephenate indole-3-glycerol SGR_RS22425 bifunctional UDP-N- lipoyl phosphotransferase SGR_RS16495 deformylase: purU RsmD: rsmD (S)-2-oxo-4- subunit CbiE: cbiE a [protein]- otsB SGR_RS10070 (5E)-3-imino-4-sulfanyl- geosmin reductoisomerase: O-phospho- o-acetylserine AMP 2'-deoxyguanosine glycerate kinase: CPT: cpt [+ 2 isozymes] octaprenyltransferase: mannosyltransferase [+ 2 isozymes] an N 2 - (2R)- [+ 6 isozymes] α α RS22080 5-oxooxolan-3- butenolide dehydrogenase: prephenate pyrroline-5- phosphate acetylglucosamine synthase: lipA CPT: cpt a malonyl- hydroxy-4-carboxy- a [protein]-L- N-phospho- , '-trehalose 5-(sulfanylmethylidene) synthase: ilvC prephenate L-homoserine sulfhydrylase: nucleoside SGR_RS05790 SGR_RS20870 MptB: mptB methylguanine 966 precorrin-8x ethylmalonyl-CoA α pyruvate yl]methyl phosphate phosphate hisD carboxylate synthase TrpC: trpC L-homocysteine ser 2'-deoxyadenosine diphosphorylase/ 7,8-dihydroneopterin [BryP acyl- 5-ureidoimidazoline proline (ω = 0) L-histidine 6- -mycolate reductase pyrrolidin-2-one SGR_RS34160 (R)-2,3-dihydroxy- prephenate dehydratase: threonine SGR_RS33225 deaminase: 2-phospho- N-acetyl-D- a N-acetylmuramoyl- carrier protein] in 16S rRNA RS25965 4-hydroxy-2,2'- L-alanine reductase: 5'-nucleotidase: glucosamine-1- a [glycine-cleavage a 1-arachidonoyl-2-acyl-sn CMP CMP a 1-palmitoyl-2- 2'-phosphate 5-undecyl-1,2- BprA: bprA 3-methylpentanoate dehydrogenase: pheA alanine synthase: (1S,2R)-1-C-(indol-3- SGR_RS17525 thymidine D-glycerate glucosamine pentapeptide- 3',5'-ADP 4'-phosphopantetheine formate a tetrahydrofolate bipyrrole-5- biosynthesis III proC SGR_RS32860 phosphate N- 5'-deoxyadenosine 6 an unsulfurated acyl-sn-glycero-3- 4-hydroxy-3- dihydropyrrol- [(3S,4R)-4-(6- (-)-geosmin his SGR_RS28625 yl)glycerol 3-phosphate cytidine purine-nucleoside met complex H protein] N -glycero-3-phosphocholine carbaldehyde dihydroxy-acid 3-phenyl-2- racemization SGR_RS12115 cystathionine thymidine acetyltransferase [sulfur carrier] phosphocholine diphosphoundecaprenol octaprenylbenzoate 3-one an A-factor type methylheptanoyl) 3-(4- cys deaminase: adenosine deaminase: phosphorylase: -[(R)-lipoyl]-L-lysine RS22235 dehydratase: pro oxopropanoate [+ 2 isozymes] beta-synthase: phosphorylase: GlmU: glmU γ-butyrolactone -5-oxooxolan-3- dithioholothin cys hydroxyphenyl) tryptophan synthase: SGR_RS13065 adenosine SGR_RS09030 SGR_RS12945 ilvD ala SGR_RS22120 SGR_RS13060 purine-nucleoside α yl]methyl phosphate cysteine pyruvate bifunctional trpB SGR_RS27290 L-glutamate biosynthesis III [+ 3 isozymes] N-acetyl- -D- thr phosphorylase: GDP-α-D- trans,octacis a 2,3,4-saturated p-nitrophenyl- 46 4-methoxy- (3S)-3-methyl-2- desulfurase: bifunctional aspartate alanine glucosamine D-glucarate 5-amino-4- a β-D-galactoside a 1,2-diacyl- 4-fumaryl- 7,8-dihydroneopterin a holo [BryU acyl- a guanine an insertion sequence a ribonucleoside a phosphate RS26205 ser 2'-deoxyuridine thymine adenosine SGR_RS12945 mannose -decaprenyl PRPP CDP-choline 1,2-diacyl-sn- β-D-galactoside a folate 15-cis-phytoene 2-chloroacetate cys 2,2'-bipyrrole- oxopentanoate SGR_RS27925 aspartate transaminase/ racemase: indole purine-nucleoside 1-phosphate imidazolecarboxyamide sn-glycerol acetoacetate 2',3'-cyclic phosphate in tRNA element IS30 5'-monophosphate monoester 2-undecylpyrrole L-cystathionine deaminase: IMP degradation II phosphate glycerol 3-phosphate CTP carrier protein] tRNA phytoene haloacid RS06225 5-carbaldehyde an IM-2 type γ- branched-chain cysteine transaminase/ aspartate 4- SGR_RS12550 2-oxoglutarate phosphorylase: bifunctional UDP-N- polyprenol ACP S- transposase: dihydrofolate alkaline 2-isocapryloyl-3R NADP-specific glutamate SGR_RS09030 2'-deoxyinosine (guanosine(46)-N7) 5'-nucleotidase: desaturase: dehalogenase cystathionine aspartate 4- decarboxylase: [+ 2 isozymes] SGR_RS12945 acetylglucosamine beta-glucosidase: beta-glucosidase: phosphomannose- malonyltransferase: SGR_RS19970 reductase: phosphatase: butyrolactone -hydroxymethyl- amino acid desulfurase: tryptophan synthase: [+ 3 isozymes] GMP IMP D-glucarate polyprenol adenine chloramphenicol fumarylacetoacetase: -methyltransferase SGR_RS32860 SGR_RS00300 type II: gamma-lyase: holothin dithioholomycin SGR_RS23555 D-ala cystathionine gamma- dehydrogenase: gdhA uracil glucarate SGR_RS01745 phosphatidate SGR_RS01745 dependent alpha 1,6 fabD [+ 5 isozymes] SGR_RS20710 γ aminotransferase: SGR_RS09975 decarboxylase: trpB SGR_RS27290 dehydrogenase: diphosphorylase/ monophosphomannose phosphoribosyltransferase: phosphotransferase SGR_RS29630 SGR_RS18125 -butyrolactone lyase: SGR_RS18125 glutamate synthase phosphorylase: 2-deoxy-α-D-ribose 1-phosphate cytidylyltransferase: fahA mannosyltransferase 7 TrmB: trmB an insertion [+ 2 isozymes] SGR_RS12395 SGR_RS09750 ala SGR_RS23555 inosine glucosamine-1- dehydratase: synthase: SGR_RS30515 SGR_RS30075 [+ 5 isozymes] CPT: cpt [+ 5 isozymes] a malonyl-[+ 2 isozymes] an N - a 7,8-dihydrofolate 9,15,9'-tri-cis RS07315 guaB 46 sequence IS30 with a ribonucleoside an alcohol pyruvate phe large subunit: gltB SGR_RS13060 5'-nucleotidase: phosphate N- SGR_RS28995 SGR_RS09120 MptB: mptB methylguanine glycolate undecylprodigiosin phosphopentomutase: 5-dehydro-4- 7,8-dihydroneopterin [BryU acyl- integrated transposon -ζ-carotene RS00740 ile tyr trp cys glu SGR_RS32860 acetyltransferase trans,octacis- carrier protein] in tRNA purine-nucleoside XMP SGR_RS34450 deoxy-D-glucarate D-galactopyranose a non galactosylated CMP D-galactopyranose acetoacetate fumarate 3'-phosphate GlmU: glmU decaprenylphospho- AICAR a phosphatidylcholine a CDP-2,3,4-saturated- 4-nitrophenol phosphorylase: 5-dehydro-4- GDP galactose acceptor holomycin uracil 2-deoxy-α-D- guanosine β-D-mannose diacylglycerol SGR_RS12945 2-deoxy-D-ribose 5-phosphate UDP-N-acetyl- deoxyglucarate ribose 1-phosphate 5'-nucleotidase: α-D-glucosamine Carbohydrate Biosynthesis dehydratase: RS07460 streptorubin B purine-nucleoside SGR_RS32860 RS13520 phosphopentomutase: hypoxanthine deoxyribose-phosphate UDP-N-acetylglucosamine SGR_RS28015 XLXG xyloglucan 3D-(3,5/4)- 1518 an N-terminal L- 37 SGR_RS34450 phosphorylase: 1-carboxyvinyltransferase: a 1-O-(alk-1-enyl)-sn-glycero- 7,8-dihydrofolate + adenine / guanine (2R,3S)-3- Nucleoside and Nucleotide Biosynthesis gluconeogenesis I aldolase: deoC 2,5- methylmalonate semialdehyde glycyl-glycine glutathione NADPH H dihydroxyacetone an acyl phosphate homogentisate acryloyl-CoA Fe 2+ acetamide UDP-α-D-galactose glycogen biosynthesis III (from α-maltose 1-phosphate) GDP-mannose biosynthesis α SGR_RS12945 SGR_RS07385 3-phosphoethanolamine oligosaccharide monoglutamate trihydroxycyclohexane- adenine 1519 in 16S rRNA alanyl-[S18 protein in tRNA Phe isopropylmalate thr UDP- -D-glucose 2-deoxy-D-ribose xanthosine deoxyribose-phosphate dioxopentanoate dihydroxyacetone biosynthesis 1,2-dione 3D-(3,5/4)- 16S rRNA of 30S ribosome]ribosomal protein tRNA 3-isopropylmalate homogentisate crotonyl-CoA amidase: biosynthesis 5-phosphate xanthine aldolase: deoC UDP-N-acetylglucosamine kinase: dhaL dhaK L-threonine 3- superpathway of pyrimidine (S)-malate D-glucopyranose guanine beta-glucosidase: trihydroxycyclohexane- (adenine(1518)-N(6)/ S18-alanine N- (guanosine(37)-N1) acylphosphatase: dehydrogenase: 1,2-dioxygenase: carboxylase/ bacterioferritin: bfr SGR_RS06590 superpathway of superpathway of guanosine superpathway of pyrimidine 5-aminoimidazole ribonucleotide biosynthesis I α ADP-α-D-glucose D-glucopyranose 6-phosphate dehydrogenase 1-carboxyvinyltransferase: CoA-acylating dihydrofolate dehydrogenase: RS23050 ribonucleotides de novo biosynthesis inosine-5'-phosphate biosynthesis I guanine and guanosine salvage guanine and guanosine salvage II UDP- -D-glucose 6-phosphate D-glucopyranose gamma- lysoplasmalogenase: adenine(1519)-N(6))- dihydroxyacetone acetyltransferase: -methyltransferase SGR_RS09335 SGR_RS09755 SGR_RS28875 reductase: RS07615 adenosine nucleotides nucleotides de novo biosynthesis I nucleobases salvage deoxyribose- molybdopterin purine-nucleoside murA methylmalonate- SGR_RS01745 reductase: 1,2-dione acylhydrolase tdh [+ 3 isozymes] UDP-glucose glucose-6-phosphate 6-phosphate glutamyltransferase: ggt SGR_RS28270 dimethyltransferase kinase: 1 TrmD: trmD ccrA alpha-D-glucose acetaldehyde D-glyceraldehyde 3-phosphate α [+ 5 isozymes] (decyclizing): iolD an N-terminal N-acetyl-rimI an N - 4-methyl-2- 4-maleyl- 3+ de novo biosynthesis I PRPP malate isomerase: pgi phosphate binding phosphorylase: UDP-N-acetyl- - 2-oxoglutarate semialdehyde SGR_RS20710 5-deoxy-D- RsmA: rsmA SGR_RS03730 dhaL a carboxylate (R)-methylmalonyl- Fe acetate AIR uracil 4-epimerase 6 1518 37 aminoacetone gln hydrogencarbonate dehydrogenase: phosphate-specific aldolase: subunit: xdhB SGR_RS12945 D-glucosamine- dehydrogenase: mmsA N -dimethyladenine L-alanyl-[S18 protein methylguanine oxopentanoate acetoacetate CoA guanosine uracil guanosine GalE: galE F6P acetaldehyde glucuronate 6 1519 Phe IMP SGR_RS13380 phosphoglucomutase: γ XXXG xyloglucan /N -dimethyladenine DHAP of 30S ribosome] in tRNA IMP asp 5-(carboxyamino) purine-nucleoside amidophosphoribosyltransferase: deoC 5'-deoxyadenosine dehydrogenase (acetylating) enolpyruvate -L-glutamyl- sn-glycero-3- 5,6,7,8- phosphoribosyltransferase: upp [+ 3 isozymes] SGR_RS33600 L-cysteinylglycine a fatty aldehyde D-galactopyranose NADP + in 16S rRNA RS06545 imidazole ribonucleotide phosphorylase: SGR_RS19190 UDP-α-D-galactose trehalose-6- bifunctional glucose-6- deoxyribose- degradation I : SGR_RS02680 UDP-N- glycylglycine phosphoethanolamine oligosaccharide tetrahydrofolate glutamine- IMP bifunctional pyr operon xanthine + pyruvate phosphate phosphate/mannose-6- α [+ 2 isozymes] acetylmuramate hydrogencarbonate NADH propanoyl-CoA H RS28155 hydrolyzing dehydrogenase: synthase: SGR_RS22245 SGR_RS12945 transcriptional regulator/uracil 5-phospho-β- gly oxaloacetate -D-glucopyranose phosphate thymine degradation adenylosuccinate synthase: phosphate isomerase: 5'-deoxyadenosine acetyl-CoA dehydrogenase: carbamoyl- guaB guanine phosphoribosyltransferase D-ribosylamine guanine 1-phosphate aldolase: xanthine synthase: N5-CAIR SGR_RS15985 SGR_RS22410 SGR_RS14240 phosphate PyrR: pyrR phosphoenolpyruvate UTP--glucose- deoC dehydrogenase S-methyl-5'- thymine SGR_RS16855 mannose-6-phosphate UDP-N-acetyl- a [pyruvate dehydrogenase E2 α a plant soluble XXLG xyloglucan D-threo-7,8- a [2-oxoglutarate a cytidine 1402 a guanine 37 (2R,3S)-3- a monocarboxylic an organic RS12650 synthase: XMP UMP phosphoribosylamine- synthase: ppsA alpha-D-glucose 1-phosphate accessory protein thioadenosine UDP-N-acetyl- -D-muramoyl- D-alanyl-D-alanine D-glucopyranose acetaldehyde 1-aminocyclopropane- sn-glycerol an aryl sulfate citrate 5-(carboxyamino)imidazole hypoxanthine hypoxanthine α a sulfurated [sulfur carrier] SAM 6 heteroglycan oligosaccharide dehydrogenase E2 protein] thr -glycine ligase: purD phosphate-specific isomerase, class I: manA uridylyltransferase D-glyceraldehyde XdhC: xdhC -D-muramate protein] N -octanoyl-L-lysine L-alanyl-γ-D-glutamyl-L-lysine dihydroneopterin 1-carboxylate in 16S rRNA in tRNA 3-phosphate isopropylmalate acid amide hydroperoxide carA carB ribonucleotide mutase: purE phosphoribosyltransferase: hpt phosphoribosyltransferase: hpt acetaldehyde phosphorylase: aldehyde dehydrogenase N 6 -dihydrolipoyl-L-lysine 16S rRNA tRNA alkyl 3-phosphate 5,6-dihydrothymine 1-aminocyclopropane- L-glyceraldehyde 3-isopropylmalate amidase: aconitate RS07775 adenylo-succinate glutamine- UMP kinase: SGR_RS09130 phosphoenolpyruvate phosphoglucomutase: D-mannopyranose 6-phosphate GalU: galU xanthine SGR_RS21310 (NADP(+)): SGR_RS07975 dihydrolipoyl (cytidine(1402)-2'-O) (guanosine(37)-N1) threonine hydroperoxide sulfatase: asp SGR_RS33600 α,α-trehalose dehydrogenase dihydropyrimidinase: 4-alpha- beta-glucosidase: 1-carboxylate 3-phosphate dehydratase: SGR_RS06590 hydratase hydrolyzing GMP CAIR GAR α acetaldehyde α UDP-N-acetylmuramoyl- dihydroneopterin dehydrogenase: -methyltransferase: -methyltransferase ammonia-lyase: reductase: SGR_RS04365 carbamoyl asp GMP UDP GMP phosphopyruvate phosphomannomutase/ UDP- -D-glucose 5-deoxy- -D- hydA glucanotransferase: SGR_RS01745 aldehyde dehydrogenase deaminase: reductase: mgrA leuD leuC [+ 3 isozymes] AcnA: acnA adenylosuccinate synthase: guaA [+ 2 isozymes] 6-phosphate dehydrogenase molybdopterin UDP-N-acetyl- tripeptide--D-alanyl-D- aldolase: folB lpdA rsmI TrmD: trmD SGR_RS12660 SGR_RS12325 RS12995 phosphate UDP-N-acetyl-D- ribose 1-phosphate lipoyl synthase: lipA malQ (NADP(+)): SGR_RS28055 SGR_RS14615 a [2-oxoglutarate a 2'-O- an N 1 - L-glyceraldehyde (2S)-2- lyase: nucleoside- phosphoribosylglycinamide hydratase: eno trehalose- phosphoglucomutase: (acetylating): binding 3-(carbamoylamino)- α alanine ligase: murF [+ 5 isozymes] a monocarboxylate a phenol D-threo-isocitrate glucosamine biosynthesis I -D-muramoyl- acetate 1402 37 2-oxobutanoate an alcohol SGR_RS05675 phosphoribosylaminoimidazolesuccinocarboxamide formyltransferase: phosphopyruvate SGR_RS22400 SGR_RS02680 subunit: xdhB S-methyl-5- 2-oxobutanoate dehydrogenase E2 methylcytidine methylguanine 3-phosphate isopropylmalate GMP diphosphate kinase: ndk phosphatase: 2-methylpropanoate L-alanyl-γ-D- 6 3+ 3+ aspartate synthase: SGR_RS19105 hydratase: eno D-glucopyranose thioribose-1- a plant soluble XXXG xyloglucan protein] N -lipoyl-L-lysine in 16S rRNA in tRNA Fe FhuB Fe adenylosuccinate SGR_RS13415 otsB α purine ribonucleosides degradation β glutamyl-meso-2,6- UDP-N-acetyl-α-D-muramoyl-L-alanyl- maltose 6-(hydroxymethyl) glycolaldehyde carbamoyltransferase UTP 6-phosphate -D-mannose 1-phosphate acetyl-CoA urate -ureidopropionase: a [pyruvate dehydrogenase heteroglycan D-galactopyranose lyase: glucose-6- phosphate diaminopimelate 5'-deoxyadenosine γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine oligosaccharide -7,8-dihydropterin catalytic subunit: guanylate CTP synthase: FGAR 2-phospho-D-glycerate α,α-trehalose isomerase: mtnA SGR_RS06015 met E2 protein] N 6 -lipoyl-L-lysine an unsulfurated [sulfur carrier] RS01125 SGR_RS31355 SAICAR phosphate SGR_RS30205 kinase: gmk SGR_RS28540 isomerase: pgi maltose alpha-D- adenosine 5-deoxy-D-ribulose (R)-3-amino-2- adenylosuccinate pyrimidine deoxyribonucleotides de novo biosynthesis III phosphoribosylformylglycinamidine RS15420 AMP CTP synthase: purS purQ purL F6P glucosyltransferase: 1-phosphate methylpropanoate lyase: SGR_RS05675 GDP-α-D-mannose α undecaprenyl-diphospho-N XLLG xyloglucan 1402 6-O-cis-keto- N-carbamoyl- GDP treS adenosine deaminase: UDP-N-acetyl- -D-glucosamine D-glucopyranose maltopentaose D-glucopyranose maltotetraose maltotriose a glucan a single a cytidine (R)-3- adenosyl-cob(III) a double adenylosuccinate UDP CTP α-D- -acetylmuramoyl-L-alanyl-γ- oligosaccharide an aldehyde hydantoin a [protein] Ser/Thr L-carnitine mycolyl-trehalose wound RNA propionamide L-aspartate FGAM 3-phospho-D-glycerate glutamine-- SGR_RS09030 stranded DNA in 16S rRNA hydroxybutanoate yrinate a,c-diamide stranded DNA lyase: SGR_RS31355 glucopyranose α aldehyde dehydrogenase serine/threonine 6-phosphate RS25960 adenylate kinase: ribonucleoside-diphosphate fructose-6- ADP-α-D-glucose -maltose [+ 3 isozymes] D-glutamyl-L-lysyl- D-alanine 16S rRNA 3-hydroxybutyrate L-carnitine cobyric acid ATP- amidase: dihydroorotase: 1-phosphate UTP and CTP dephosphorylation I (NADP(+)): SGR_RS28055 deoxyribonuclease dihydropyrimidinase: protein kinase: trehalose- DNA: SGR_RS13895 reductase: SGR_RS11310 phosphoribosylformylglycinamidine phosphoglycerate phosphate undecaprenyldiphospho- 4-alpha- 4-alpha- beta-glucosidase: 4-alpha- (cytosine(1402)-N(4) dehydrogenase: dehydrogenase: synthase: dependent SGR_RS06590 SGR_RS30210 nucleoside- ribonucleoside- AICAR CDP IV: SGR_RS26880 hydA SGR_RS18370 phosphatase: gyrB gyrA SGR_RS11315 cyclo-ligase: SGR_RS19195 kinase: transaminase maltokinase: xanthosine adenosine inosine guanosine acetaldehyde DHAP pyrimidine deoxyribonucleotides muramoylpentapeptide beta-N- glucanotransferase: glucanotransferase: SGR_RS01745 glucanotransferase: aldehyde dehydrogenase )-methyltransferase SGR_RS05825 SGR_RS33235 SGR_RS28150 RNA helicase [+ 3 isozymes] RS15730 ADP diphosphate diphosphate UTP dephosphorylation (NADP(+)): SGR_RS07975 RsmH: rsmH [+ 13 isozymes] otsB HrpA: hrpA bifunctional vitamin B12-dependent ribonucleoside-diphosphate SGR_RS27800 (isomerizing) SGR_RS10320 acetylglucosaminyltransferase: malQ malQ [+ 5 isozymes] malQ an N 4 - a negatively (S)-dihydroorotate kinase: ndk reductase: a 5'-phosphooligonucleotide N-carbamoylglycine a [protein] (L-serine/L- acetoacetate 3-dehydrocarnitine adenosylcobyrate trehalose-cis-keto- propanoate phosphoribosylaminoimidazolecarboxamide ribonucleotide reductase: reductase: SGR_RS11310 AIR : glmS GDP-L-fucose biosynthesis nucleoside triphosphate murG a carboxylate methylcytidine 1402 an unwound RNA supercoiled DNA RS01255 vitamin B12- SGR_RS11310 13-DPG CTP synthase: threonine) phosphate mono-mycolate formyltransferase/IMP cyclohydrolase: purH SGR_RS08385 SGR_RS11315 glutamine-- α-maltose 1- I (from GDP-D-mannose) pyrophosphohydrolase: in 16S rRNA quinone- dependent SGR_RS11315 purine-nucleoside purine-nucleoside purine-nucleoside purine-nucleoside SGR_RS28540 maltose maltotetraose maltose maltotriose XXXG xyloglucan a glucan D-glucopyranose dUDP vitamin B12-dependent superpathway of pyrimidine deoxyribonucleoside salvage fructose-6- phosphate SGR_RS22025 ditrans,octacis-undecaprenyldiphospho- UDP D-galactopyranose dependent ribonucleotide GTP FAICAR type I GDP-α-D- phosphorylase: phosphorylase: phosphorylase: phosphorylase: UDP dCTP dCMP oligosaccharide vitamin B12- nucleoside- ribonucleotide reductase: phosphate pseudouridine N-acetyl-(N-acetylglucosaminyl)muramoyl- dihydroorotate reductase: glyceraldehyde- alpha-1,4-glucan-- β mannose SGR_RS12945 SGR_RS12945 SGR_RS12945 SGR_RS12945 CTP γ RS15840 dependent diphosphate kinase: ndk SGR_RS08385 2'-deoxycytidine transaminase dTDP- -L-rhamnose GDP- degradation L-alanyl- -D-glutamyl-L-lysyl-D-alanine dehydrogenase: SGR_RS08385 bifunctional 3-phosphate maltose-1-phosphate RarD ribonucleotide (isomerizing) biosynthesis mannose 4,6- dUTP diphosphatase: dut SGR_RS30230 phosphoribosylaminoimidazolecarboxamide dUTP dCDP dehydrogenase: maltosyltransferase: α pseudouridine ribonucleoside- reductase: nucleoside dehydratase: -D-ribose-1-phosphate nucleoside triphosphate 3-(4- 967 PRPP formyltransferase/IMP cyclohydrolase: purH : glmS SGR_RS10310 α-D-glucopyranose UMP 4a-hydroxy-L- α a long-linear a cytosine 7,8-dihydro- orotate diphosphate SGR_RS08385 dUTP diphosphatase: dut nucleoside- deaminase: gap dethiobiotin a sulfurated D-glucopyranose maltohexaose a sialyloligosaccharide -D-glucopyranose α uroporphyrinogen-III protoporphyrinogen IX trans-aconitate 2-hydroxyisobutyramide 4-nitrocatecholsulfate N-ethylmaleimide NaMN D-glucopyranose adenine and adenosine salvage III D-glucosamine a (1->4)- 1-phosphate GDP-4-dehydro-gmd S-methyl-5'- CDP pyrophosphohydrolase: SAM erythro-5,6,7,8- -D-glucan hydroxyphenyl) in 16S rRNA L-homoserine 8-oxoguanine reductase: diphosphate kinase: ndk SGR_RS17525 glyceraldehyde- glucose-1-phosphate phosphopentomutase: 5'-nucleotidase: SGR_RS22025 [sulfur carrier] pyruvate a reduced nucleoside triphosphate dCMP 6-phosphate α-D-glucan α-D-rhamnose thioadenosine tetrahydrobiopterin4a-hydroxytetrahydrobiopterin rRNA cytosine-C5- trans-aconitate 2- amidase: alkene 8-oxoguanine xylose orotate SGR_RS11310 IMP pyrophosphohydrolase: cytidine deaminase: 3-phosphate thymidylyltransferase SGR_RS34450 pseudouridine SGR_RS32860 dUTP dUMP uroporphyrinogen protoporphyrinogen sulfatase: 5'-nucleotidase: cystathionine isomerase: H O c-type dCTP GDP-L-fucose degradation II 4-alpha- dehydratase: SGR_RS17540 4-alpha- 4-hydroxyphenylpyruvate methyltransferase: methyltransferase: SGR_RS06590 reductase: deaminase: 2 cytochrome RS02625 phosphoribosyltransferase: SGR_RS11315 (d)CMP kinase: triose-phosphate dehydrogenase: phosphoglucosamine 1,4-alpha- RfbA: rfbA 5'-phosphate exo-alpha-sialidase: decarboxylase: hemE oxidase: hemG SGR_RS04365 SGR_RS32860 gamma-lyase: cytochrome dGDP xanthine and SGR_RS22025 SGR_RS13065 adenine synthase: S-methyl-5'- D-ribose 5-phosphate uridine biotin glucanotransferase: glucanotransferase: dioxygenase: hppD SGR_RS30280 SGR_RS21735 [+ 3 isozymes] SGR_RS28080 SGR_RS06385 xylA c oxidase an oxidized SGR_RS16930 SGR_RS00880 isomerase: SGR_RS04535 mutase: SGR_RS13830 glucan CMP SGR_RS32130 4a-hydroxytetrahydrobiopterin SGR_RS18125 xanthosine salvage glucose-1-phosphate thioadenosine pseudouridine- synthase malQ malQ a 5-methylcytosine 967 (E)-3- 2-hydroxy-2- β-D- O c-type dUMP (d)CMP kinase: purine-nucleoside branching SGR_RS07540 S-methyl-5'- 5-hydroxy-CTP 5-hydroxy-CMP dehydratase: SGR_RS05510 keto-D-fructose 2 nucleoside- 2'-deoxyuridine SGR_RS27805 D-glyceraldehyde α-D-glucosamine thymidylyltransferase: 5'-nucleotidase: BioB: bioB (6R)-L-erythro-6,7- homogentisate coproporphyrinogen III protoporphyrin IX (methoxycarbonyl) 4-nitrocatechol N-ethylsuccinimide 2-oxobutanoate urate a reduced dADP SGR_RS28630 phosphorylase: DHAP enzyme: GDP-4-dehydro- thioadenosine 5'-phosphate in 16S rRNA methylpropanoate ribosylnicotinate cytochrome orotidine 5'- diphosphate FAD-dependent thymidylate 3-phosphate 1-phosphate SGR_RS29590 SGR_RS32860 dihydrobiopterin pent-2-enedioate H O c-type SGR_RS12945 glgB 6-deoxy-β- phosphorylase: glycosidase: a short 1,4- 2 phosphate xanthosine synthase: SGR_RS08710 thymidine kinase: dCDP dTDP-α-D-glucose maltopentaose maltose N-acetylneuraminate an oligosaccharide cytochrome RS07630 nucleoside- kinase: ndk adenosine bifunctional UDP-N- L-galactose SGR_RS21310 SGR_RS27690 cytidine biotin 5'-deoxyadenosine an unsulfurated α-D-glucan CtaD an oxidized purine-nucleoside dTMP SGR_RS08210 Alcohol Degradation met orotidine-5'- diphosphate nucleoside- acetylglucosamine a GlgE-glycogen dTDP-glucose 4,6- GDP-L-fucose 5-MTR-1-P uracil [sulfur carrier] O c-type phosphorylase: 2 phosphate kinase: ndk dGTP dTMP kinase: thymidine diphosphate adenosine deaminase: class II fructose- diphosphorylase/ dehydratase: rfbB synthase: cytochrome SGR_RS12945 dUMP SGR_RS09030 glucosamine-1- dTDP-glucose 4,6- glycerol and glycerophosphodiester degradation decarboxylase: xanthine SGR_RS16335 kinase: ndk bisphosphate SGR_RS07540 glycerol degradation V pyrF dATP thymidine kinase: [+ 3 isozymes] aldolase: fbaA phosphate N- dehydratase: rfbB 3-methyl-2- 5,10-methylene- 6-[1-hydroxyethyl]-7- 4a-hydroxy-N 10 - (2R)-phospho- (S)-2- γ-glutamyl- dCTP RS28245 adenine and dTDP dCTP GDP-β-L-fucose D-glucopyranose a maltodextrin chloroacetaldehyde viomycin uroporphyrinogen-I oxaloacetate a cytosine in DNA chloramphenicol hydroquinone a chitodextrin pyrazinamide SGR_RS08210 acetyltransferase dTDP-4-dehydro-6- glycerol oxobutanoate tetrahydromethanopterin methyl-7,8-dihydropterin formyltetrahydrofolate 3-sulfolactate hydroxyglutarate isopropylamide dCTP UMP adenosine salvage I Detoxification glycerol 4a-hydroxytetrahydrobiopterin aldehyde dehydrogenase DNA cytosine CMP nucleoside- inosine GlmU: glmU PRPP biosynthesis deoxy-α-D-glucopyranose 2-amino-4-hydroxy-6- 2-phosphosulfolactate phosphoenolpyruvate CatB-related O- L-2- chitinase: ferredoxin: amidase: deaminase: diphosphate kinase: ndk N-acetyl-α-D- 4-alpha- hydroxymethyldihydropteridine dehydratase: SGR_RS05510 (NADP(+)): SGR_RS28055 viomycin uroporphyrinogen phosphatase: carboxykinase (GTP) methyltransferase: acetyltransferase: hydroxyglutarate tyrosinase: SGR_RS33595 SGR_RS25825 SGR_RS06590 UMP kinase: phosphorylation β-D-fructose 1,6- dTDP-4- 3-methyl-2-oxobutanoate SGR_RS17045 purine-nucleoside glucosamine D-ribose 5- reactive oxygen species degradation glucanotransferase: diphosphokinase: folK 4a-hydroxytetrahydrobiopterin aldehyde dehydrogenase phosphotransferase: vph decarboxylase: hemE SGR_RS03220 : SGR_RS12600 SGR_RS23260 SGR_RS24415 oxidase: lhgO SGR_RS02500 [+ 2 isozymes] SGR_RS09130 adenosine dTTP bisphosphate dehydrorhamnose arsenate a glycerophosphodiester hydroxymethyltransferase: [+ 2 isozymes] [+ 3 isozymes] dUTP CMP XMP dTMP 1-phosphate arsenate dihydroxyacetone [1-(2-amino-7-methyl-4-oxo- dehydratase: SGR_RS17540 (NADP(+)): SGR_RS07975 [+ 4 isozymes] N,N'- γ purine-nucleoside phosphorylase: phosphate 3,5-epimerase: panB malQ 10 phosphoenol chloramphenicol N-( -L-glutamyl) pyrazine-2- RS07780 UDP (d)CMP kinase: class II fructose- ribose-phosphate detoxification V detoxification glycerol an N -formyl- O-phosphoviomycin coproporphyrinogen I (2R)-3-sulfolactate a 5-methylcytosine 2-oxoglutarate 1,4-benzoquinone diacetylchitobiose phosphorylase: dTMP kinase: SGR_RS12945 bifunctional UDP-N- SGR_RS29575 7,8-dihydro-3H-pteridin- 2-chloroacetate pyruvate 3-acetate -L-alaninol carboxylate SGR_RS00880 bisphosphatase: diphosphokinase: superoxide II (glutaredoxin) dihydroxyacetone 7,8-dihydrofolate in DNA nucleoside- SGR_RS12945 SGR_RS16335 acetylglucosamine dTDP-4-dehydro- glycerophosphoryl 6-yl)]ethyl diphosphate (d)CMP kinase: glpX SGR_RS21775 arsenate kinase subunit a maltodextrin maltose diphosphate adenine dTDP hypoxanthine diphosphorylase/ PRPP β-L-rhamnose superoxide glyceraldehyde- arsenate diester glycerol kinase DhaK: dhaK 2-dehydropantoate THMPT kinase: ndk SGR_RS28630 glucosamine-1- dismutase: arsenate phosphodiesterase: GlpK: glpK gln CDP F6P dTDP-4- 3-phosphate RS01685 adenine nucleoside- phosphate N- SGR_RS24435 reductase ArsC: SGR_RS24450 glycerol kinase DHAP UTP hypoxanthine dehydrorhamnose dehydrogenase: nucleoside- phosphoribosyltransferase: diphosphate glucose-6- acetyltransferase SGR_RS08560 [+ 6 isozymes] GlpK: glpK reductase: rfbD superoxide SGR_RS04535 2,5-diamino-6-(5- trans,octacis-decaprenylphospho- a 2-O-(α-D-mannosyl)-1- 5-dehydro-2- 55 phosphoribosyltransferase: hpt 38-40 3-phenyl-2- α a uridine a double-stranded (indol-3-yl) β a supercoiled CTP diphosphate SGR_RS30075 kinase: ndk phosphate GlmU: glmU dismutase, Ni: sodN 1-arseno-3- arsenite phospho-D-ribitylamino) seleno-L- β a uridine in tRNA an -limit dextrin 4-guanidinobutyramide reduced riboflavin GDP- -L-fucose ferroheme o CTP synthase: β -D-arabinofuranose phosphatidyl-1D-myo-inositol oxopropanoate deoxy-D-gluconate in tRNA oligonucleotide acetamide duplex DNA kinase: ndk dTTP isomerase: pgi UDP-N-acetyl- dTDP- -L-rhamnose phosphoglycerate pyrimidin-4(3H)-one homocysteine decaprenylphospho-beta- RluA family pseudouridine phosphatidylinositol dCTP SGR_RS28540 sn-glycerol 3-phosphate bifunctional 5-dehydro-2- 4-alpha- tRNA amidase: FMN reductase: amidase: GDP-L-fucose DNA helicase: heme A AMP IMP D-glucopyranose α-D-glucosamine hydrogen peroxide 5-methyltetrahydropteroyltriglutamate- D-erythro-pentofuranosid- synthase: SGR_RS27090 mannoside 4-hydroxyphenylpyruvate oligoribonuclease: deaminase: RS08160 CTP diaminohydroxyphosphoribosylaminopyrimidine deoxygluconokinase: glucanotransferase: pseudouridine(55) SGR_RS06590 SGR_RS18845 SGR_RS06590 synthase: SGR_RS23225 synthase: 6-phosphate - homocysteine S- 2-ulose 2-reductase: acyltransferase: dioxygenase: hppD orn SGR_RS17045 CTP deaminase/5-amino-6-(5-phosphoribosylamino) tRNA pseudouridine(38- iolC malQ synthase TruB: truB [+ 3 isozymes] [+ 2 isozymes] [+ 3 isozymes] SGR_RS07540 [+ 5 isozymes] SGR_RS27885 methyltransferase: metE SGR_RS13325 SGR_RS30015 a α-limit dextrin GDP-4-dehydro- UTP catalase: 1-arseno-3- arsenite uracil reductase RibD: ribD trans,octacis-decaprenylphospho- 40) synthase TruA: truA a 2-O-(6-O-acyl-α-D-mannosyl)- (2-hydroxyphenyl) 5-dehydro-2-deoxy-D- a pseudouridine 55 a nucleoside 5'- a single 5-amino-6-(5-phospho- 38-40 with short branches 4-guanidinobutanoate riboflavin (indol-3-yl)acetate α-D-rhamnose ferroheme a SGR_RS06465 phosphoglycerate SeMet β-D-erythro-pentofuranosid-2-ulose a pseudouridine in tRNA 1-phosphatidyl-1D-myo-inositol acetate gluconate 6-phosphate in tRNA monophosphate stranded DNA [+ 3 isozymes] DHAP D-ribitylamino)uracil H O hydroxyl radical RS29355 2 O 2 a branched- a branched- a reduced chain chain a reduced plastocyanin spermidine an amino an amino an amino an amino RS03530 (2-aminoethyl) amino acid amino acid plastocyanin a dicarboxylate asp asp a purine putrescine acid acid acid acid phosphonate an oxidized choline choline D-glucose 6- an aliphatic a carbohydrate a carbohydrate an inorganic an inorganic an inorganic a nicotinamide a nicotinamide an oxidized glycine betaine glycine betaine glycine betaine sn-glycerol a C4- D-fructose an a sugar 6- an amino an amino an amino an amino an amino ala ala (S)-lactate benzoate queuosine queuosine plastocyanin arsenite ammonium ammonium glycine betaine glycine betaine a tricarboxylate a tricarboxylate a tricarboxylate glutamate an amino pyrimidine phosphate sulfonate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate anion anion anion mononucleotide mononucleotide plastocyanin pro pro pro 3-phosphate dicarboxylate 1-phosphate oligopeptide phosphate acid acid acid acid acid predicted predicted pro pro acid ABC ABC predicted predicted predicted predicted predicted predicted ABC predicted ABC predicted ABC transporter transporter ABC ABC ABC ABC ABC transporter of cytochrome TatC RS07920 RS14810 RS02560 RS26190 RS25005 RS24115 RS34500 FtsE RS11905 RS21595 RS13070 RS11155 RS05435 RS20255 AspT AspT RS05320 RS10590 RS32785 RS10420 RS19280 RS09895 RS18780 RS09715 RS25325 RS03820 RS30670 RS10130 RS06835 RS03610 transporter of RS03890 RS02055 RS04045 transporter of RS11210 RS11945 RS34345 RS22825 RS06440 RS13665 RS00950 RS24260 RS06920 RS26320 RS07335 RS01330 RS15905 of a of a RS25800 RS08065 RS31030 RS32800 RS32910 RS30425 RS28585 CtaD ArsB transporter RS05255 RS04060 RS09295 RS20335 RS22925 ProP RS29390 RS28810 RS28815 RS28820 UgpC RS10350 RS33290 RS08500 RS32105 RS34280 RS22165 transporter transporter transporter transporter RS11005 RS34395 RS24870 RS01180 RS20905 RS20340 RS10940 RS11290 RS21460 RS21935 SecA RS34375 RS12450 RS24705 RS25720 RS26720 SecG RS28390 RS08095 MycP (2-aminoethyl) c oxidase a carbohydrate a carbohydrate branched- branched- of spermidine/ of an of an of an of an phosphonate chain chain putrescine amino acid amino acid amino acid amino acid choline choline D-glucose an aliphatic a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate amino acid amino acid an inorganic an inorganic an inorganic a nicotinamide a nicotinamide glycine betaine glycine betaine glycine betaine sn-glycerol a C4- D-fructose an a sugar an amino an amino an amino an amino pyrimidine (S)-lactate benzoate queuosine queuosine arsenite ammonium ammonium glycine betaine glycine betaine a tricarboxylate a tricarboxylate a tricarboxylate glutamate sulfonate a carbohydrate a carbohydrate anion anion anion mononucleotide mononucleotide O pro pro pro 3-phosphate dicarboxylate oligopeptide acid acid an amino acid acid an amino ala ala (2-aminoethyl) 2 O pro pro 2 spermidine acid acid phosphonate H O an amino an amino an amino an amino asp asp a branched- a branched- 2 H O putrescine a purine 2 acid acid acid acid chain chain a dicarboxylate amino acid amino acid This diagram was automatically generated by SRI International Pathway Tools version 25.0, authors S. Paley and P.D. Karp.