DOCSLIB.ORG

Biological Engineering

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Biological Engineering Biological Engineering Study and Engineer Biology to … •develop molecular therapeutics (antibodies, peptides, small molecules, antivirals) •improve drug delivery (antibodies, peptides) •develop cellular therapeutics (tissue engineering, microbiome engineering) •improve chemical production (commodity chemicals and specialty chemicals) •enhance bioenergy production (biofuels, photosynthesis and carbon fixation) Biological Engineering at Multiple Scales Molecules Reed Murphy Romero Palecek Shusta Pfleger Yin Cells/Viruses Palecek Shusta Pfleger Venturelli Reed Yin Cell Populations & Tissues Palecek Venturelli Shusta Yin Romero Lab: Data-driven protein engineering Molecular simulation Machine learning Protein design Collaborators AI-driven biological discovery • Jim Dumesic • Brian Pfleger • Jennie Reed Technology development • Ophelia Venturelli • Statistics, Biochemistry Understand structure-function relationships Murphy Lab: Amyloid protein misfolding & aggregation protein disease beta-amyloid Alzheimer disease alpha-synuclein Parkinson disease huntingtin Huntington disease transthyretin Senile systemic amyloidosis cystatin C Cerebral amyloid angiopathy www.sheffield.ac.uk/ mbb/staff/staniforth Collaborators Starting polypeptides are diverse in sequence, structure and • Eric Shusta function but their aggregates share common structural features and cause disease • Reid van Lehn • What are the kinetics and mechanisms of aggregation? • Pharmacy • How do amyloid proteins exert biological effects on cells? • Can we design compounds or systems that interfere with aggregation? Brain Uptake of Retinol in Alzheimers (a) AD# (b) (c) TTR-RBP v transfers re*nol# Aβ v retinol RBP# (Vitamin A) TTR# TTR$ RBP$ across cell re(nol$ membrane (d) (e) hRBP% aRBP% re(nol$ RDH$ CRBP$ Retinol regulates re(nal$ transcription of RALDH$ re(noic$acid$ RAR/RXR$ RARE$ other proteins CRABP$ LRAT% CRBP% How does Ab get metabolism$ from the brain into the blood? v v How does retinol cross the BBB? What roles do TTR and RBP play? v v Pfleger Lab: Synthetic Biology Collaborators • Jennie Reed What do we study? • Phil Romero • Gene discovery and characterization • Ophelia Venturelli • Gene expression, regulation • Jim Dumesic • Synthetic biology tool development • Metabolic engineering • George Huber • Functional genomics and systems biology • Thatcher Root • Bioreactor studies and bioprocess design • Christos Maravelias • Victor Zavala Applied • Microbiology, Genetics, Microbiology Biochemistry • PSU, UIUC (CABBI), UNL Vanderbilt Synthetic Systems Biology Biology Model-Guided Thioesterase Engineering Goal: Create mutants of ‘TesA with specificity for octanoic (C8) acid and dodecanoic (C10) acid • Iterative Protein Redesign & Optimization (IPRO) based on crystal structure information. • Minimize interaction energy for C8:0 and maximize interaction energy for undesired substrates (C14:0). Organism Escherichia coli of origin Native 53 % C14:0, 38 % selectivity C12:0 M. Grisewood C. Maranas J. Thoden H. Holden N. Hernández-Lozada B. Pfleger Crystal Available Computational Crystallography of Variant Construction structure (1U8U; 2FAE) enzyme design WT and top variant and Testing Usage Biodiesel – Steen et al., Nature Methyl-ketones – Goh et al., AEM top 10 octanoic acid producing mutants* Reed Lab: Systems Biology • Discover enzyme functions 40-60% of genes have unknown function • Engineer metabolic & regulatory Collaborators networks for chemical production • Brian Pfleger • Phil Romero • Understand microbe-microbe and microbe-host interactions • Christos Maravelias Image • Ophelia Venturelli courtesy of McFall-Ngai • Microbiology, ECE, ISYE, Lab Biochemistry, Vet School Optimize Expression Constructs to Maximize Valine Production What combinations of RBSs and genes are needed to maximize valine yields? Kumar, Adamczyk et al. To be submitted Venturelli Lab: Engineering Gut Microbiome Computational modeling Microbiome engineering Negative interaction Positive interaction BV CA BT CH BH DP BU BO PC Actinobacteria Bacteroidetes Firmicutes FP Proteobacteria ER EL Collaborators • Brian Pfleger • Jennie Reed • Phil Romero Microfluidic technologies • Victor Zavala • Microbiology Rapid inference of microbial interaction networks in microfluidic droplets Venturelli awarded the 2017 ARO Young Investigator Provisional patent filed Hsu RH et al. In review Palecek Lab: Stem Cell Biomanufacturing Processes to generate clinical grade cells from human pluripotent stem cells Collaborators • Dave Lynn • Eric Shusta • Medical School (Cell & Regenerative Cardiac aggregates ‘omics discovery of critical Biology, Medicine), quality attributes Biochemistry, to treat heart disease Chemistry, BME • Georgia Tech, U. Puerto Rico Mayaguez, UCSF Human Pluripotent Stem Cells (hPSCs) Properties of hPSCs: 1. Pluripotent – ability to generate all cell types found in the adult 2. Potential for infinite self-renewal A system to study early developmental processes A source of cells and tissues for screening effects of drugs and other chemical compounds A clonal source of vast amounts of desired cells and tissues for therapeutic applications Lutolf et al. Nature, 2009 Shusta Lab: Antibody Engineering & BBB Antibody Discovery iPSC Differentiation Technology Protein Engineering PK/Biodistribution Blood-Brain Barrier Modeling “Blood-Brain Barrier” Nanoparticles/ Modeling the Diseased NVU controlled release Neurovascular Unit Collaborators • Regina Murphy • Sean Palecek Therapeutic Development • Dave Lynn • Medical School (Neurosurgery, Pathology), Biomedical Engineering • Cedars Sinai/UCSD Getting therapeutics across the blood-brain barrier Mouse injected with radiolabeled Histamine (111 Da) Pardridge, Brain Drug Targeting, 2001 BBB controls transport of substances into and out of the brain: -Provides the brain with nutrients -Transports metabolites out of the brain -Maintains brain homeostasis -Regulates immune function -Implicated in a number of diseases -Serves as a significant bottleneck for brain drug delivery -98% of small molecule pharmaceuticals do not cross BBB -Only lipophilic, small molecules diffuse through Using hPSC to a Build Blood Brain Barrier Model Collaboration between Prof. Palecek and Prof. Shusta Differentiation (Lippmann, Azarin et al., Nature Biotech, 2012) (Wilson et al., FBCNS, 2015) (Qian et al., Science Advances, 2017 • Human BBB endothelial cells Human pluripotent • Scalable stem cells (hPSC) • Substantial barrier (Lippmann et al., Scientific Reports, 2014) (Canfield et al., J Neurochem, 2017) (Stebbins et al., Science Advances, 2019) Differentiation Astrocytes & Neurons Neural stem cells Yin Lab: Systems Approaches to Biology Chemistry Virus input Q: How can reactions of simple chemicals (e.g., amino acids) begin to show behaviors* of living systems? * store information, self replicate, adapt host cell Drying- induced de novo Virus output peptide Q: How can material and energy flows synthesis during virus growth give insights into how diseases spread and persist? How bad is your cold? Identify biomarkers and potentially drug targets for human rhinovirus infections (common cold). Human rhinovirus Palmenberg, Biochemistry Pediatric immunology Gern, Sch. Med. Pub. Health Biostatistics/machine learning . Roy, Biostat. Med. Info. Student Experiences • Patent Applications • Internships • WARF Ambassadors Ø Cargill Ø Merck • UG Research Mentors Ø Genencor • DELTA Interns Ø Genentech • K-12 Outreach Ø Dupont Ø Dow Agrosciences (Corteva) • Training Programs Ø Intrexon • Campus Seminars Ø LS9 • Conferences Ø AbbVie Ø USDA • International Research Ø Kimberly-Clark • Funded Grants • Great Lakes Bioenergy Research Center (GLBRC) • Metabolomics and Proteomics • Fermentation Facilities • JGI Sequencing and DNA Synthesis • Bigger Picture of Overall Challenges • Communication with Broader Science Community Involvement in Campus Life Science Initiatives Cross-Disciplinary Training Programs • Biotechnology Training Program • Computation and Informatics in Biology and Medicine • Genomic Sciences Training Program • Clinical Neuroengineering Training Program • Chemistry-Biology Interface Training Program • Cellular and Molecular Pathology Training Program • Neuroscience Training Program • Virology Training Program Cross-Disciplinary Graduate Colleagues • Cellular and Molecular Biology Training Program • MicroBiology Doctoral Training Program • Biomedical Engineering • Material Science • Chemistry • Biophysics • Food Science Centers • UW Stem Cell and Regenerative Medicine Center • UW Comprehensive Cancer Center • Great Lakes Bioenergy Research Center • NSF ERC Cell Manufacturing Technologies (Georgia Tech, U Georgia, U Puerto Rico).
Load more

Recommended publications
  • Biological Engineering (BIOE)
    2021-2022 Academic Catalog BIOE3100 METABOLIC ENGINEERING BIOLOGICAL ENGINEERING An engineering approach to microbiology and bio-based products. As bioengineering continues to grow as a discipline, biomanufacturing (BIOE) using "microbial cell factories" continues to pique the interests of the entrepreneur. Commodity compounds, from amino acids to BIOE2000 FUNDAMENTALS OF BIOLOGICAL ENGINEERING biopolymers, can be manufactured fermentatively. With a growing This course introduces students to the fundamental concepts of list of organismal genome sequences available for analysis and Biological Engineering. Knowledge of thermodynamics and fluid manipulation, organisms ( mainly microorganisms) will be utilized and mechanics is critical for students to solve biological engineering subsequently manipulated by the growing number of molecular biology problems. Students will learn about energy, entropy and enthalpy in their and synthetic biology techniques available. Students will utilize the various forms in a biological setting. Students will also learn basic fluid methods and concepts taught in this course for problem solving in statics and dynamics. These topics will be applied in assignments, exams biotechnology, biomanufacturing and the biopharmaceutical fields. and in the laboratory to solve biomedical and biochemical engineering This course discusses cellular and organismal metabolic networks and problems. Case studies are presented to allow student to put together the mathematical and experimental manipulation of those networks. their
    [Show full text]
  • Undergraduate Handbook
    Department of Chemical and Biological Engineering Undergraduate Handbook Academic Year 2021-2022 Revised: June 2021 Engineering Biology Certificate Bioengineering & Biotechnology Engineering & Sustainable Entrepreneurship Environmental Management Energy Certificate Studies Certificate Certificate Certificate Energy & Entrepreneurship Environmental & Management Technology The Chemical and Biological Engineering Materials Science Applied Math Certificate Major Certificate Materials & Optimization, Product Dynamics & Engineering Information Engineering Physics Technology Certificate Science & Engineering for New Technologies Table of Contents WHAT IS CHEMICAL AND BIOLOGICAL ENGINEERING? .................................... 2 THE EDUCATION OF A CHEMICAL AND BIOLOGICAL ENGINEER ........................ 3 CERTIFICATE PROGRAMS .............................................................................. 19 INDEPENDENT WORK ................................................................................... 20 GRADUATION REQUIREMENTS ..................................................................... 24 ACADEMIC HONORS ..................................................................................... 24 HONOR SOCIETIES, AWARDS, AND PRIZES .................................................... 25 ADVISING ..................................................................................................... 28 EXTRACURRICULAR ACTIVITIES ..................................................................... 29 POST GRADUATION PLANS ..........................................................................
    [Show full text]
  • Dr. Junghae Suh to Be Inducted Into Medical and Biological Engineering Elite
    For further information, contact Charlie Kim Director of Membership & Operations [email protected] February 15, 2021 Dr. Junghae Suh to be inducted into medical and biological engineering elite WASHINGTON, D.C.— The American Institute for Medical and Biological Engineering (AIMBE) has announced the election of Junghae Suh, Ph.D., Vice President; Professor, Gene Therapy Accelerator Unit, Biogen to its College of Fellows. Dr. Suh was nominated, reviewed, and elected by peers and members of the College of Fellows for significant contributions in synthetic virology and biomolecular engineering to design gene delivery technologies for controlled drug delivery. The College of Fellows is comprised of the top two percent of medical and biological engineers in the country. The most accomplished and distinguished engineering and medical school chairs, research directors, professors, innovators, and successful entrepreneurs comprise the College of Fellows. AIMBE Fellows are regularly recognized for their contributions in teaching, research, and innovation. AIMBE Fellows have been awarded the Nobel Prize, the Presidential Medal of Science and the Presidential Medal of Technology and Innovation and many also are members of the National Academy of Engineering, National Academy of Medicine, and the National Academy of Sciences. A formal induction ceremony will be held during AIMBE’s 2021 Annual Event on March 26. Dr. Suh will be inducted along with 174 colleagues who make up the AIMBE Fellow Class of 2021. For more information about the AIMBE Annual Event, please visit www.aimbe.org. AIMBE’s mission is to recognize excellence in, and advocate for, the fields of medical and biological engineering in order to advance society.
    [Show full text]
  • CALL for PAPERS IEEE Transactions on Nanobioscience Thematic Issue: “Nano/Molecular Medicine and Engineering”
    CALL FOR PAPERS IEEE Transactions on Nanobioscience Thematic Issue: “Nano/Molecular Medicine and Engineering” The IEEE Transactions on Nanobioscience will devote a themed issue “Nano/Molecular Medicine and Engineering” to a collection of papers highlighting research and technology development in the field of nano-biotechnology, molecular engineering, micro/nano-fluidics, micro/nano-system integration, nano-biology and nano-medicine. IEEE Nanotechnology Council is sponsoring the 9th IEEE International Conference on Nano/Molecular Medicine and Engineering (IEEE-NANOMED 2015) held on November 15–18, 2015, Honolulu, HI, USA to foster interaction between physicians, scientists, engineers in these emerging areas. Areas of interest include but are not limited to: • Nano and molecular technologies in medical theranostics • Nanotechnology in drug delivery • Biomedical imaging • Bio/nano sensing • Biochips and Bio-MEMS • Biomechatronics • Biological interface • Cells at the nanoscale • Nanomaterials for tissue engineering and biology • Frontiers in nanobiotechnology • Translational medicine Submissions are solicited from conference participants and other researchers in the field for a review paper or a research paper for this themed issue. Manuscripts will be subject to the normal peer review procedures of the IEEE Transactions on Nanobioscience. Follow the guideline (http://tnb.embs.org/forauthors.html), and submit your paper to Manuscript Central at http://mc.manuscriptcentral.com/tnbembs, indicating in the cover letter that you wish the paper to be considered for the Special Issue “Nano/Molecular Medicine and Engineering”. Submission deadline: July 15, 2016 Anticipated publication: November, 2016 Please address all other correspondence regarding this special issue to the Guest Editors: Jin-Woo Kim, Ph.D. Professor, Biological Engineering, Biomedical Engineering, Nanoscience & Engineering University of Arkansas, USA Email: [email protected] Deok-Ho Kim, Ph.D.
    [Show full text]
  • Nanotechnology Nanobiotechnology, Optoelectronics, Nanocomposites, Nanostructures, Mechanical Properties, Corrosion, Materials Processing
    al ring c e ine g Chemi En Graduate Students Faculty M Scien a t erials c e UCI Students QUICK FACTS: Founded in 1965, the University of California, Irvine combines the strengths of a major research university with the bounty of an incomparable Southern California location. UCI’s unyielding commitment to rigorous academics, cutting-edge research, and leadership and character development makes the campus a driving force for innovation and discovery that serves our local, national and global communities in many ways. With nearly 28,000 students, 1,100 faculty members and 9,000 staff, UCI is among the most dynamic campuses in the University of California system. Increasingly a first-choice campus for students, UCI ranks among the top U.S. universities in the number of undergraduate applications and continues to admit freshmen with highly competitive academic profiles. Orange County’s largest employer, UCI generates an annual economic impact on the county of $4.2 billion. Rankings & Distinctions Chancellor Michael Drake EXCELLENCE IN ACADEMICS & RESEARCH: UCI fosters the passionate and enthusiastic expansion of knowledge through quality education. Graduates are equipped with the tools of analysis, expression and cultural understanding necessary for leadership in today’s world. Consistently ranked among the nation’s best universities – public and private – UCI excels in a broad range of fields, garnering national recognition for many schools, departments and programs. Three UCI researchers have won Nobel Prizes – two in chemistry and one in physics. The university is noted for its top-rated research and graduate programs, extensive commitment to undergraduate education, and growing number of professional schools and programs of academic and social significance.
    [Show full text]
  • Biological Engineering: a Newdiscipline for the Next Century
    Biological Engineering: A NewDiscipline for the Next Century Bernard Y. Tao* ABSTRACT BIOTECHNOLOGY:FRIEND OR FOE’,? Increasingawareness and concern about living systemsand The wordbiotechnology stirs a mixture of uncertain the useof biologicaltechnology has led to demandfor individu- emotionsin most people (Davis, 1991). Visions of medi- als withan understandingof the life sciencescombined with engineeringskills. Importantsocial/economic issues involving cal miracles coexist with unsettling fears about rampant environmentalquality, the use of recombinantgenetics in killer microbes, genetically altered foods, and bionic/ foods/pharmaceuticals,andthe qualityof life havecreated a cyborg"robocops." This dichotomyexists because of the thrivingjob marketfor individualswho understand the eco- fundamentalbelief that living systemsshould not be tech- nomics,science, and technology of dealingwith living systems nological products. Technologyis perceived as a means andtheir products.A new discipline, Biological Engineering, to alter or transform the environment to meet human has evolvedin responseto this growingneed for technological- needs. Engineers synthesize plastics, build magnetic ly trainedindividuals with backgrounds in the life sciences.This trains, and create digital televisions. Peoplecontrol tech- articlereviews the issues driving the need for biological engineer- nology. But whenit comesto transformingliving systems ing disciplineand summarizes current curricula at severaluniver- into controlled, engineeredcommodities, there is a funda-
    [Show full text]
  • Biological Engineering 2013-2014
    Biological Engineering 2013-2014 DEPARTMENT OF BIOLOGICAL AND ENVIRONMENTAL ENGINEERING Mission Statement Educate the next generation of professionals and discover new knowledge in biological engineering; Disseminate cutting edge research-based engineering information through scientific media and outreach programs; Conduct all programs in the context of a world-class university and deliver the highest value knowledge to our students, citizens, and global society. Our Commitment The educational objectives of the Biological Engineering program are consistent with those of the College of Engineering and Cornell University. We are committed to providing an excellent undergraduate engineering program in a nurturing environment where our graduates acquire knowledge and develop skills for professional success. Graduates of our program include a diverse group of leaders and problem solvers who contribute technically, professionally and personally to our society. The Educational Objectives of the Biological Engineering Program are to 1. Advance in careers and opportunities related to Biological Engineering and other related fields and professions based on a solid educational background in appropriate mathematics, physical and life sciences, liberal studies (including communication and ethics) and engineering. 2. Pursued advanced degrees in engineering and related professional fields. Undergraduate Program Department of Biological and Environmental Engineering 2013-2014 Cornell University is an equal opportunity, affirmative action educator. Handbook cover designed by Ed Evans and Brenda Marchewka. Pictures on cover from left to right: 1. New Brunswick Scientific 150L Fermentation reactor housed in the Biofuels Research Labs, 2. Scanning electron micrograph of synthetic intestinal villi, 3. Pore structure inside a parboiled rice grain, 4. Microfluidic device to mimic the cancer cell environment, 5.
    [Show full text]
  • Engineering Life: Building a Fab for Biology
    BY THE BIO FAB GROUP * *David Baker, George Church, Jim Collins, Drew Endy, Joseph Jacobson, Jay Keasling, Paul Modrich, Christina Smolke and Ron Weiss Principles and practices learned from engineering successes can help transform biotechnology from a specialized craft into a mature industry lthough the term “genetic engineering” has been in use for at least three decades, and recombinant DNA methods are now mainstays of modern re- search, most biotechnologists’ work with living things has little in common with engineering. One Areason is that the tools available for building with biological “parts” have yet to reach a level of standardization and utility equal to that in other engineering fields. Another has to do with methods and mind-sets in biology, although these, too, can be powerfully influenced by technology. Electronic engineering, for example, was transformed be- ginning in 1957, when Jean Hoerni of Fairchild Semiconduc- tor, a small company in what would later be known as Silicon Valley, invented planar technology. It was a system for layer- ing and etching metals and chemicals within silicon wafers using templates called photomasks. This new approach al- lowed engineers to produce integrated circuits cleanly and BIOLOGICAL COMPONENTS consistently and to create a wide variety of circuit types just are the basis of an approach by changing the pattern on the photomask. Soon engineers to biotechnology modeled on could draw from libraries of simple circuits made by others electronics engineering. S L IM F IL M S 44 SCIENTIFIC AMERICAN JUNE 2006 COPYRIGHT 2006 SCIENTIFIC AMERICAN, INC. C REDI T www.sciam.com SCIENTIFIC AMERICAN 45 COPYRIGHT 2006 SCIENTIFIC AMERICAN, INC.
    [Show full text]
  • Bioengineering at MIT Introduction SB in Biological Engineering Biological
    BE.010 Spring 2005 Session #4 notes Bioengineering at MIT Outline of this session: - overview of the new Biological Engineering (BE) undergraduate major at MIT note: the following is a summary of the new SB Degree in Biological Engineering at MIT by the School of Engineering Biological Engineering Division Introduction Professor of Biological and Mechanical Engineering Linda G. Griffith is the director of the Biotechnology Process Engineering Center at MIT. She is interested in the applications of tissue engineering to replace damaged body parts, such as lost cartilage in the bone. SB in Biological Engineering The molecular and genomic revolutions in the past decades paved the path for a greater degree of overlap between two previously distinct fields. These revolutions made it possible for researchers to explore and develop new engineering applications to biology. The new undergraduate degree program in BE at MIT was developed in response to these changes. Proposed by the School of Engineering Biological Engineering Division and co-chaired by Linda G. Griffith and Roger D. Kamm, it is designed to be an extension to the PhD program in BE at MIT. Biological Engineering vs. Biomedical Engineering The BE major stands distinct from Biomedical Engineering (BME). While BE employs engineering to the life sciences, particularly to biology, BME makes use of a wide range of engineering techniques to advance clinical medicine specifically. The emphasis on biology in BME is not always stressed. Students majoring in BE have a much broader view of engineering applications in biology when compared with students in BME. The MIT schools of science and engineering are working to develop a wide range of options with which to explore biological engineering, such as BME, Mechanical Engineering (course 2a), Electrical Engineering (course 6) with a biology related concentration, among others.
    [Show full text]
  • Engineering in Medicine & Biology
    ® Engineering in Medicine & Biology Designing a Career in Biomedical Engineering Robot-assisted surgery. Photo courtesy The Acrobot Company, Ltd. (www.acrobot.co.uk) Copyright © 2003 IEEE. All Rights Reserved. Copyright and Reprint Permissions: Reprinting of this infor- mation is permitted with credit to the source. Libraries are permitted to photocopy beyond the limit of U.S. copyright law for private use of patrons those articles in this volume that carry a code at the bottom of the first page, provided the per-copy fee indicated in the code is paid through Copyright Clearance Center, 222 Rosewood Drive, Danvers, MA 01923. For other reprint or republications permission, write to IEEE Intellectual Property Rights Manager, IEEE Operations Center, 445 Hoes Lane, Piscataway, New Jersey USA 08854. Is biomedical engineering right for you? What kind of career do you imagine for yourself? Doctor? Lawyer? Scientist? Engineer? Teacher? CEO? Manager? Salesperson? A university degree in biomedical engineering will prepare you for all of these professions and more. Biomedical engineers use their expert- ise in biology, medicine, physics, mathematics, engineering science and communication to make the world a healthier place. The challenges cre- ated by the diversity and complexity of living systems require creative, knowledgeable, and imaginative people working in teams of physicians, scientists, engineers, and even business folk to monitor, restore and enhance normal body function. The biomedical engineer is ideally trained to work at the intersection of science, medicine and mathematics to solve biological and medical problems. What do biomedical engineers do? Perhaps a simpler question to answer is what don’t biomedical engineers do? Biomedical engi- neers work in industry, academic institutions, hospitals and govern- ment agencies.
    [Show full text]
  • The Institute of Biological Engineering President's Message
    Inside... IBE Meeting Highlights The Institute of Executive Director’s Report Biological Engineering Biology in Engineering Biological Engineer at Work www.ibeweb.org IFAQ Poster and Essay Winners Summer 2008 Volume 12.2 President’s Message Christina D. Smolke [email protected] Editor, Art Johnson What Does it Take to Be a Good Biological Engineer? The 21st century presents global challenges in the environment, resources, energy, health, and sustainability. The mission of the IBE is to support the com- The story is recounted in the Phi munity of scientists and engineers who are addressing these problems through Kappa Phi Forum about a Har- biological systems. We do this through enhancing and promoting biological vard University conference entitled engineering in the broadest manner through research, education, and professional “Keeping Kids in the Achievement development. Game” (Malone, 2008). John Mer- The solutions to these societal challenges will require broad multi-pronged row, President of Learning Matters, approaches – spanning engineering, biology, chemistry, materials, computer sci- Inc., and a renowned education ence, and physics. The breadth of approaches required are well-refl ected in the reporter for PBS and NPR, gave a membership of IBE and in the exciting work that was presented at our 2008 an- compelling speech about the impor- nual meeting. From researchers who are taking inspiration from natural biological tance of quality teachers, holistic systems to develop approaches for building new organic-inorganic hybrid
    [Show full text]
  • BSBE Biological Engineering Fall 2017
    BSBE Biological Engineering Fall 2017 This document is an example of a BSBE program of study. Several factors can affect the course scheduling sequence. For a copy of the official curriculum, please go to the UGA Bulletin: http://bulletin.uga.edu/ Major Requirements Students must earn a grade of "C" (2.0) or better in the courses indicated in bold. High Demand Entrance Requirements To be considered as a candidate for BSBE, students must complete the courses indicated in italics. For more information on entrance requirements, please refer to the UGA Bulletin: http://bulletin.uga.edu/ and our website. YEAR ONE Fall Semester Hours Spring Semester Hours MATH 2250 Calculus I 4 MATH 2260 Calculus II 4 ENGR 1920 Intro to Engineering 1 CHEM 1212&L Freshman Chemistry II 4 ENGR 1120 Engineering Graphics 2 PHYS 1251 Physics for Engineers I 3 ENGR 1140 Computational Engr. Methods 2 BIOL 1107&L Principles of Biology I 4 CHEM 1211&L Freshman Chemistry I 4 FYOS First-Year Odyssey 1 ENGL 1101 English Composition I 3 Total Credit Hours 16 Total Credit Hours 16 YEAR TWO Fall Semester Hours Spring Semester Hours MATH 2500 Multivariable Calculus 3 MATH 2700 Differential Equations 3 ENGR 2120 Statics 3 ENGR 3160 Fluid Mechanics 3 PHYS 1252 Physics for Engineers II 3 ENGR 2110 Engineering Decision Making 3 BIOL 1108&L Principles of Biology II 4 ENGR 2170 Electrical Circuits 3 CHEM 2211&L Organic Chemistry I 4 AENG 2920 Design Methodology 2 ENGL 1102 English Composition II 3 Total Credit Hours 17 Total Credit Hours 17 YEAR THREE Fall Semester Hours Spring Semester
    [Show full text]