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QUICK FACTS: Founded in 1965, the University of California, Irvine combines the strengths of a major research university with the bounty of an incomparable Southern California location. UCI’s unyielding commitment to rigorous academics, cutting-edge research, and leadership and character development makes the campus a driving force for innovation and discovery that serves our local, national and global communities in many ways. With nearly 28,000 students, 1,100 faculty members and 9,000 staff, UCI is among the most dynamic campuses in the University of California system. Increasingly a first-choice campus for students, UCI ranks among the top U.S. universities in the number of undergraduate applications and continues to admit freshmen with highly competitive academic profiles. Orange County’s largest employer, UCI generates an annual economic impact on the county of $4.2 billion.

Rankings & Distinctions Chancellor Michael Drake

EXCELLENCE IN ACADEMICS & RESEARCH: UCI fosters the passionate and enthusiastic expansion of knowledge through quality education. Graduates are equipped with the tools of analysis, expression and cultural understanding necessary for leadership in today’s world. Consistently ranked among the nation’s best universities – public and private – UCI excels in a broad range of fields, garnering national recognition for many schools, departments and programs. Three UCI researchers have won Nobel Prizes – two in chemistry and one in physics. The university is noted for its top-rated research and graduate programs, extensive commitment to undergraduate education, and growing number of professional schools and programs of academic and social significance.

Panoramic view of UCI campus

1 The Henry Samueli School of

About the School: Founded in 1965, The Henry Samueli School of Engineering at the University of California, Irvine is at the forefront of education and research in the engineering disciplines that will shape the future of the nation and the world. With rapidly expanding academic programs and a growing number of faculty and students, the Samueli School is becoming a powerhouse for innovative and the development of tomorrow’s advanced technologies. Through an integrative and cross- disciplinary educational experience that blends fundamentals, research and hands-on experience, we train future leaders in the engineering profession. Working in partnership with state and federal agencies and industry, the School promotes the transfer of research to applications that benefit society. The School’s faculty members are scholars and leaders in their disciplines and have achieved world wide honors and recognition for their pioneering research and dedicated teaching. More than a third of our faculty members are Fellows in professional societies and 10 have been Dean Gregory Washington elected as members of the National Academies.

Focused Research: The School is equipped with excellent experimental facilities and a state-of-the-art computational infrastructure, occupying nearly 295,000 assignable square feet. It offers numerous research centers, institutes and facilities, including the Center for Pervasive Communications and Computing, The Edwards Lifesciences Center for Advanced Cardiovascular Technology (Edwards), the Integrated Nanosystems Research Facility (INRF), the National Fuel Research Center (NFCRC), the UC Irvine Combustion Lab, the Center for Embedded Computer Systems, the Center for Hydrometeorology and Remote Sensing, the Laboratory for Fluorescence Dynamics, the Center for Advanced Monitoring and Damage Inspection, the Center for Engineering Science in Design, and the Micro/Nano Fluidics Fundamentals Focus Center. The School’s faculty is also active in the Institute of Transportation Studies, the Networked Systems Center, the Beckman Laser Institute & Medical Clinic, the Urban Water Research Center, and the Chao Family Comprehensive Cancer Center. In addition, the School is an integral part of the California Institute for Telecommunications and Information Technology (Calit2), one of four Institutes for Science and Innovation within the University of California.

By-the-Numbers (2010-11): Full-time faculty: 106 Undergraduate enrollment: 2,579 Graduate enrollment: 720

Ranked 39th in U.S. News & World Report’s 2012 listing of best engineering graduate schools and a top 25 public engineering program 2 The Department of and (ChEMS)

About the Department: Chemical engineering activities concentrate in two areas: and , which includes expression, metabolic engineering, engineering, , cell and engineering, biomaterials, colloids, and drug delivery; and, transport phenomena, which includes fluid, heat and mass transport in biological systems; laser-induced transport processes with applications in microfluidics, biology, and ; transport of biological particles (i.e., viruses, , protozoa) through environmental systems.

Materials science areas include: synthesis, mechanical behavior, and characterization of advanced nanostructured materials; ceramics and sol-gel processing; device packaging and manufacturing; electronic and optical materials; lightweight structures and multifunctional materials; microbiological corrosion of metals and alloys; biomaterials; polymers and related and nanocomposites; creep and superplasticity; fuel Albert Yee cell and related system materials; device physics; and, Professor and Chair coatings and multilayers.

Department Facts and Figures: • Undergraduate accredited degree programs: Chemical Engineering and Materials Science Engineering • Graduate Degrees: M.S. and Ph.D. programs in Chemical and and Materials Science and Engineering • 37 affiliated research active faculty . 17 with primary appointments in Chemical Engineering and Materials Science . 20 with primary appointments in other units on campus • Four faculty awarded the prestigious National Science Foundation Early Career Development Award, and one faculty member awarded the prestigious Presidential Award for Excellence in Mathematics, Science and Engineering Mentoring • Two senior faculty designated by ISI Knowledge as "Highly Cited Researchers," an honor bestowed on only 0.5% of authors worldwide

Department’s home: Engineering Tower Aerial view of the UCI campus 3 Graduate Programs in Chemical Engineering and Materials Science

Graduate Advisor for Chemical and Graduate Advisor for Materials Science Biochemical Engineering and Engineering (CBE) Professor Ali Mohraz (MSE) Professor Regina Ragan (949) 824-2028 (949) 824-6830 [email protected] [email protected]

CBE Graduate MSE Graduate Student Handbook Student Handbook

4 Core Faculty in Chemical Engineering and Materials Science

Primary Appointments

NANCY JIM ALON ALLON DA SILVA EARTHMAN GORODETSKY HOCHBAUM

YOUNG JIK FARGHALLI MARTHA ALI KWON MECARTNEY MOHAMED MOHRAZ

DANIEL HUNG MIKAEL REGINA ELIZABETH MUMM NGUYEN NILSSON RAGAN READ

FRANK VASAN SZU-WEN ALBERT SHI VENUGOPALAN WANG YEE 5 Research in Chemical Engineering and Materials Science

Endoglucanase Sciences and Biotechnology catalyzes the hydrolysis of Stem cells, , biomaterials, cellulose

biotechnology, pharmaceuticals, biomedical Da Silva diagnostics and devices

Artificial Cell Wang Membranes

Dodecahedral cages Nguyen for drug delivery Virus self-assembly Ragan

Gorodetsky Kwon Hochbaum

Electrochemistry of neuronal cells Magnetically directed transduction by Self-assembling bioothogonally engineered retroviruses bacterial communities Core Research Labs: Da Silva, Gorodetsky, Hochbaum, Kwon, Nguyen, Ragan, Read, Wang, Venugopalan, Yee

Current biochemical engineering research is directed at molecular level processes, the cell, tissues, the , and large-scale manufacturing in biochemical processes. Our department has extensive expertise in cloned expression, gene amplification and integration, metabolic engineering, bioseparation processes (including membrane and chromatographic separation), protein , bioreaction and bioreactor engineering, modeling, optimization and control of , cell and tissue engineering, the biology and of the human lung as an integrated, whole organ, wound healing and tissue remodeling. Tissue engineering research at UC Irvine takes many forms, and involves active collaboration between chemical and materials scientists with biomedical engineers, surgeons, and cell/molecular . In the ChEMS department, fundamental research addressing the interactions between cells and novel biomaterials is being conducted , along with more applied research designed to vascular networks into tissue constructs for implantation in vivo. 6 Research in Chemical Engineering and Materials Science

Nanotechnology , Optoelectronics, nanocomposites, nanostructures, mechanical properties, corrosion, materials processing

Ragan Yee

Engineering Catalytic Activity

Mohraz Wang

Fractal Colloidal Nanoparticle absorption on two- Scaffolds: differentiation Clusters dimensional protein crystals

Gorodetsky Kwon Mohamed

500 nm

Designed modular Stimuli-responsive transformation of polymeric Orientation map for nano- nanoribbons nanoparticles for gene delivery crystalline Ni

Nguyen Mecartney Peptide assembly in monolayer as template Nanoparticle Characterization using AFM

Core Research Labs: Earthman, Gorodetsky, Hochbaum, Kwon, Mohraz, Mohamed, Mumm, Mecartney, Nguyen, Ragan, Shi, Wang, Yee

Nano-structured materials (or simply "nanomaterials") are of great practical and theoretical interest due to their high surface-to-volume ratios and quantum size effects. In the ChEMS Department, nanomaterial research is applied to regenerative medicine (human embryonic stem cell proliferation and differentiation); sustainable energy (enhancing device performance of solar cells and optimizing catalysts); information technology (converting electronic and optical signals to increase bandwidth and speed); and, high throughput methods for nano-scale device manufacturing. 7 Research in Chemical Engineering and Materials Science

Energy

Bio-renewable, nuclear fuel, fuel

cells, solar cells

Core Research Labs: Da Silva, Gorodetsky, Hochbaum, Nilsson, Mohraz, Mumm, Mecartney, Yee Dr. George Miller

Mohraz

50 μm Prof. Mikael Nilsson

Da Silva

Mohraz & Mumm: Composites for Fuel Cell Applications

Metabolic Gorodetsky Hochbaum Engineering of Yeast for Biofuels Yeast Production

Synthesis and transport Ethanol DNA-Templated Nanowires properties of nanowires for as organic photovoltaics solar energy

Energy research in ChEMS is focused on developing enabling technologies that improve the performance of alternative energy sources (biofuels, solar power, solid oxide fuel cells, advanced nuclear energy production), and improve the energy efficiency of critical systems (advanced gas turbines, LED-light sources). 8 Research in Chemical Engineering and Materials Science

Functional and Micro-Structured Materials Self-assembly, composites, colloids, microfluidics

Mohamed Mecartney Ragan

substrate

nanowires

island 10 nm 50 µm

Au/disilicide electronic structures Orientation map for large-grained Mullite 3Al2O3· 2SiO2 as nanoscale catalysts polycrystalline Ni observed by electron backscatter diffraction

50 μm

50 μm

Mohraz Wang Bicontinuous composites with well- Macroscopic domains of streptavidin defined and tunable microstructure grown at the air/water interface

Core Research Labs: Earthman, Mecartney, Mohamed, Mohraz, Mumm, Ragan, Wang, Yee

The mechanical, biological, electronic, and photonic properties of technologically-important materials are often strongly mediated by the details of their internal microstructures. Examples include the rheology of complex fluids, deformation of micro- and nano-grained structural materials and composites, electrochemical performance of fuel cell and battery components, and the regenerative function of synthetic tissue. Microstructured Materials research in ChEMS aims to better understand or develop such correlations and use them for the design and assembly of advanced microstructured materials.

9 Da Silva Lab Molecular Biotechnology [email protected] http://www.eng.uci.edu/users/nancy-da-silva

Research Summary: A major focus of our research is metabolic pathway engineering in yeast, focusing on both the development of improved methods and their application to diverse pathways. The research emphasizes molecular level design combined with subsequent application and analysis. Our work ranges from engineering Saccharomyces cerevisiae for the synthesis of polyketides (a very valuable class of pharmaceuticals) and collagen-based biopolymers, to engineering yeast for biorenewable and environmental applications. Current projects in my lab include: 1. Development of Tools for Metabolic Pathway Engineering Focus is on the stable introduction and expression of multiple Prof. Nancy A. Da Silva to optimize pathway engineering in yeast Full Professor

2. Microbial Metabolic Engineering for the Synthesis of Biorenewable Chemicals (Member of CBiRC, an NSF Engineering Research Center) • B.S. Chemical Engineering, U. 3. Metabolic Engineering of Yeast for Biofuels Production Massachusetts, Amherst Use of cellulosomes to control the display of enzymes on the cell (1982) surface for increased synergy and rapid uptake of the released • M.S. Chemical Engineering, 4. Optimizing S. cerevisiae for the Synthesis of Polyketides California Institute. of Primary focus are the fungal iterative polyketide synthases for 6-MSA Technology (1985) and lovastatin synthesis 5. Synthesis and Characterization of Cell-Responsive Biopolymers • Ph.D. Chemical Engineering, Expression and application of collagen-based biopolymers useful for tissue engineering, drug delivery, and stem cell research

Key Publications: • S. Srikrishnan, A. Randall, P. Baldi, N.A. Da Silva*. 2012. Rationally selected single-site mutants of the Thermoascus aurantiacus endoglucanase increase hydrolytic activity on cellulosic substrates. Biotechnol. Bioeng. In press. • N.A. Da Silva*, S. Srikrishnan. 2012. MiniReview: Introduction and expression of genes for metabolic engineering applications in Saccharomyces cerevisiae. FEMS Yeast Res. In press. • F. Fang, K. Salmon, M.W.Y. Shen, K.A. Aeling, E. Ito, B. Irwin, U. Tran, G.W. Hatfield, N.A. Da Silva*, S. Sandmeyer*. 2011. A vector set for systematic metabolic engineering in Saccharomyces cerevisiae. Yeast. 28:123-136. • D. Shah, M.W.Y. Shen, W. Chen, N.A. Da Silva*. 2010. Enhanced arsenic accumulation in Saccharomyces cerevisiae overexpressing transporters Fps1p or Hxt7p. J. Biotechnol. 150:101-107. • S.W.P. Chan, S.-P. Hung, S.K. Raman, G.W. Hatfield, R.H. Lathrop, N.A. Da Silva*, S.-W. Wang*. 2010. Recombinant human collagen and biomimetic variants using a de novo gene optimized for modular assembly. Biomacromolecules. 11:1460-1469. • S.M. Ma, J.W.-H. Li, J. W. Choi, H. Zhou, K.K.M. Lee, V.A. Moorthie, X. Xie, J.T. Kealey, N.A. Da Silva, J.C. Vederas*, and Y. Tang*. 2009. Complete reconstitution of a highly-reducing iterative polyketide synthase. Science. 326:589-592. 10 Earthman Lab Damage and Deformation Processes [email protected] http://www.eng.uci.edu/users/james-earthman

Research Summary: Prof. Earthman's research activities

investigate a broad range of deformation and damage processes in both model and advanced materials including:

(1) fatigue (2) corrosion

(3) high temperature deformation and failure

His work also involves the development of computer-based techniques for:

(1) characterizing the dynamic mechanical behavior of materials and tissues

(2) determining mechanical biocompatibility

(3) probing the effect of living cells on corrosion Prof. James C. Earthman (4) assessment of green corrosion control technologies Full Professor (5) noninvasive characterization of surface defects in situ • B.S. Materials Science, Rice

University (1980) Consequently, he is currently an inventor on five issued US patents, • M.S. Materials Science & two international patents, and three pending US patents. Engineering, Stanford University (1982)

• Ph.D. Materials Science &

Key Publications: • “Biological Functionalization of a Sol-Gel Coating for the

Mitigation of Microbial-Induced Corrosion (MIC),” R. Akid, H. Wang, T. J. Smith, D. Greenfield, and J.C. Earthman, Advanced Functional Materials 2008, 18, 203-211. • “Laser-Scanning Structural Health Monitoring with Wireless Sensor Motes,” B. D. Buckner, V. Markov, L.-C. Lai, and J. C.

Earthman, 2008, 47, paper 054402. • “Influence of Electrical Discharged Machining and Surface

Defects on the Fatigue Strength of Electrodeposited Nanocrystalline Ni,” L.-C. Lai, W.-A. Chiou, and J. C. Earthman, International Journal of Fatigue 2010, 32, 584–591. AFM image of protective bacteria encapsulation in a sol gel coating. • “Composite Model of the Shark's Skeleton in Bending: A novel architecture for biomimetic design of functional compression

bias,” X. Liu, M. N. Dean, A. P. Summers, and J. C. Earthman, Materials Science and Engineering C 2010, 30, 1077-1084.

• “Thermal Stability of Cryomilled Nanocrystalline Aluminum Containing Diamantane Nanoparticles,” K. Maung, R. K. Mishra, I. Roy, L.-C. Lai, F. A. Mohamed, J. C. Earthman, Journal of TEM image of nanocrystalline Al Materials Science 2011, 46, 6932-6940. + Diamantane after thermal exposure at 500°C for 10 hours. 11 Gorodetsky Lab Biomolecular Electronics [email protected] http://gorodetskygroup.org

Research Summary: Our group works at the intersection of physics, chemistry, biology, and materials science. We use a multidisciplinary approach to explore questions of fundamental interest to human health and renewable energy. The ongoing projects in the group include:

1) The synthesis and purification of graphene nanoribbons with

rationally designed and programmable electronic properties.

2) The synthesis of DNA-templated organic electronic nanowires for applications in efficient organic photovoltaics and electrical . Prof. Alon A. Gorodetsky 3) The construction of biomimetic cyanobacterial hydrogen Assistant Professor production systems at nanostructured surfaces. • B.S. Materials Science & B.S. 4) The development of carbon nanotube-based biosensors for Cornell the early stage detection of pancreatic cancer. University (2003) 5) The fabrication and self-assembly of protein thin films for biologically-inspired cloaking devices • Ph.D. Chemistry, California

Key Publications: • H. Wang, N. Muren, D. Ordinario, A. A. Gorodetsky, J. K. Barton, C. Nuckolls. Transducing Methyltransferase Activity into Electrical Signals in a Carbon Nanotube-DNA Device. Chem. Sci. 2012, 3, 62. • M. Palma, J. Abramson, A. A. Gorodetsky, R. L. Gonzalez, C. Nuckolls, M. P. Sheetz, J. Hone, S. J. Wind. Selective Biomolecular Nanoarrays for Parallel Single Molecule Investigations. J. Am. Chem. Soc. 2011, 133, 7656. • M. Cox, A. A. Gorodetsky, B. Kim, K. S. Kim, Z. Jia, P. Kim, C. Nuckolls, I. Kymissis. Single-Layer Graphene Cathodes for Organic Photovoltaics. Appl. Phys. Lett. 2011, 98, 123303. • A. A. Gorodetsky, C.-Y. Chiu, T. Schiros, M. Palma, M. Cox, Z. Jia, W. Sattler, I. Kymissis, M. Steigerwald, C. Nuckolls. Reticulated Heterojunctions for Photovoltaic Devices. Angew. Chem. Int. Ed. 2010, 49, 7909. • A. A. Gorodetsky, L. E. P. Dietrich, P. E. Lee, B. Demple, D. K. Newman, J. K. Barton. DNA Binding Shifts the Redox Potential of the Transcription Factor SoxR. Proc. Natl. Acad. Sci. U.S.A. 2008, 105, 3684. • X. Guo, A. A. Gorodetsky, J. Hone, J. K. Barton, C. Nuckolls. Conductivity of a Single DNA Duplex Bridging a Carbon Nanotube Gap. Nat. Nanotechnol. 2008, 3, 163. 12 Hochbaum Lab

[email protected] http://hochbaumlab.eng.uci.edu

Research Summary: In the Hochbaum Lab we are interested in nanoscale interfaces. We study inorganic and biological- inorganic interfaces to understand and create devices which

address pressing issues in global energy demand and human health. We specialize in the synthesis of nanoscale, bioinspired and biomimetic materials, and study the chemical and physical interactions between microbes and minerals. We have ongoing

research projects in the following areas:

1. Earth-abundant nanomaterials for clean energy devices: earth-abundant minerals typically have more impurities and poorer properties than state-of-the-art semiconductors. Prof. Allon However, by rational design of the material structure Hochbaum through nanoscale syntheses, one may construct efficient, Assistant Professor inexpensive, and scalable devices.

2. Extracellular electron transfer in microbial biofilms: Many • S.B. Materials Science and Engineering, MIT(2003) mundane and extremophilic bacteria use extracellular electron transfer in their metabolic pathways. • Ph.D. Chemistry, University Electrochemical methods can offer insight into the of California, Berkeley mechanisms of charge transfer in these systems, and hybrid devices incorporating such electroactive bacteria with (2008) inorganic components are promising for power generation and biofuels synthesis.

3. Ordered and mixed-species biofilms: Most naturally- occurring microbial communities are composed of multiple – often syntrophic – species. The deterministic structuring of these communities may be used to systematically study the relationships between bioflm structure and function with relevance to medical infections and stimulated biofuels production.

Key Publications: 1. “Inhibitory effects of D-amino acids on Staphylococcus aureus biofilm development,”A.I. Hochbaum, I. Kolodkin- Gal, L. Foulston, R. Kolter, J. Aizenberg, R. Losick, J. Bacteriol., 193, 5616, 2011. 2. “Bacteria pattern spontaneously on periodic nanostructure arrays,” A.I. Hochbaum, J. Aizenberg, Nano Lett., 10, 3717, 2010. 3. “Enhanced thermoelectric efficiency of rough silicon nanowires,” A.I. Hochbaum, R. Chen, R.D. Delgado, W. Liang, E.C. Garnett, M. Najarian , A. Majumdar, P. Yang, , 451, 163, 2008.

13 Kwon Lab BioTherapeutics Engineering Laboratory (BioTEL) [email protected] https://sites.google.com/a/biotel.biz/home/biotel

Research Summary: Timely, complete, and convenient treatment of many diseases is not yet within reach, although many potent therapeutics have been identified and developed. Synthesis of novel nanomaterials, innovative fabrication of carriers, elucidation of extracellular and intracellular behaviors of drug/carriers, and development of new drug release mechanisms are the key scientific emphases in the BioTEL. The ultimate goal in

BioTEL is to develop universally applicable delivery platforms for combined diagnosis and therapy with pinpointed specificity and accuracy, and hence, maximum therapeutic effects in vitro and in vivo, by bridging biology and medicine using techniques from engineering, synthetic chemistry, and nanotechnology. Representative current research projects are: 1. Acid-degradable polymers for nonviral gene delivery Prof. Young Jik Kwon 2. Viral/nonviral chimeric core-shell nanoparticles for synergistic Associate Professor therapy • B.S. , 3. Bioorthogonally engineered enveloped viruses for gene Inha University, Korea (1998) therapy and vaccination • M.S. Chemical Engineering, 4. Stimuli-responsive nanomaterials for combined imaging and University of Southern therapy (nanotheragnostics) California (2000) 5. DNA-based cancer • Ph.D. Chemical Engineering, 6. Nanoantibiotics for treating drug-resistant infections

Key Publications:  Cho SK, Kwon YJ. Simultaneous gene transduction and silencing using stimuli-responsive viral/nonviral chimeric nanoparticles. Biomaterials (in press; published online).  Kwon YJ. Before and after endosomal escape: Roles of stimuli- converting siRNA/polymer interactions in determining gene silencing efficiency. Accounts of Chemical Research (in press; published online).  Huh AJ, Kwon YJ. "Nanoantibiotics': A new paradigm for treating infectious diseases using nanomaterials in the antibiotics resistant era. Journal of Controlled Release 156, 128-145 (2011).  Wong S, Kwon YJ. Synthetically functionalized retroviruses produced from the bioorthogonally engineered cell surface. Bioconjugate Chemistry 22, 151-155 (2011).  Shim MS, Kim CS, Ahn Y-C, Chen Z, Kwon YJ. Combined multi- modal optical imaging and targeted gene silencing using stimuli- transforming nanotheragnostics. Journal of the American Chemical Society 132, 8316-8324 (2010).  Shim MS, Kwon YJ. Acid-transforming polypeptide micelles as efficient, biocompatible, and versatile nonviral gene carriers. Biomaterials 31, 3404-3413 (2010). 14 Mecartney Lab Advanced Ceramic Materials [email protected] http://www.eng.uci.edu/users/martha-mecartney

Research Summary: Professor Mecartney has published over 100 articles, primarily research on developing high tech ceramics

for applications in electronics and energy. She has been recognized both as an outstanding instructor, receiving the Professor of the Year award at UC Irvine, and as an exemplary mentor, receiving the Presidential Award for Excellence in Science, Math, and Engineering

Mentoring presented by the White House. She also has been recognized for her research by the David and Lucille Packard Fellowship for Science and Engineering. Her current research

interests are in ceramics for energy applications where she studies how grain boundaries and interfaces control physical properties of Prof. M.L. Mecartney ceramics, projects in collaboration with industry and Los Alamos National Laboratory. Her group conducts studies on the synthesis Full Professor of materials, characterization of microstructures (using state-of- • B.S. MSE, Case Western the-art SEM, TEM, AFM, and XRD) , thermal and ionic behavior, and Reserve University, (1979) computational materials science approaches to virtual materials • M.S. Materials Science & design for these projects. Three projects are currently ongoing. Engineering, Stanford 1. Improved materials for solid oxide electrolytes for fuel cells University (1980) and sensors. This project area encompasses both • Ph.D. Materials Science & alternative materials development (Sr doped LaPO4 proton Engineering, Stanford conductors) and multiphase ceramic development (second phase University (1984) additives in yttria-stabilized zirconia).

2. Multiphase ceramics for nuclear energy applications including

inert matrix nuclear fuel and nuclear waste. This project has implications for enhanced efficiency and better thermal management for these systems.

3. The development of low thermal conductivity materials for environmental barrier coatings. This research involves the

understanding how new phases of oxide materials interact with the environment and impurities in the atmosphere at high Multiphase temperatures. Ceramics

Key Publications: Solid Oxide 1. M.C. Martin and M.L. Mecartney. “Grain Boundary Ionic Electrolytes Conductivity of Yttria Stabilized Zirconia as a Function of Silica Content and Grain Size,” Solid State Ionics, 161 [1-2] 67-79 (2003).

2. M.T. Schatzmann, M. L. Mecartney, and P.E.D. Morgan, “Synthesis of Monoclinic Monazite, LaPO4, by Direct Precipitation,”

J. of Mater. Chem. 19 [32] 5720-5722 (2009). 3. C. M. Hoo, D. Men, L. Taherabadi, M. L. Mecartney, “Grain Boundary Sliding in a Superplastic Three - Phase Alumina - Zirconia Computational - Mullite Ceramic Composite,” Journal of the American Ceramic Modeling of Society, 97 [7] 2171-2180 (2011). Virtual Materials 15 Mohamed (FAM) Lab Mechanical Behavior of Engineering Materials [email protected] http://fam.eng.uci.edu

Research Topics:

• Mechanical behavior of engineering materials (metals, alloys, composites, ceramics, nanocrystalline materials) • Correlation between behavior and microstructure

• Creep and superplasticity • The role of impurities during superplastic deformation and

cavitation • Dynamic recrystallization • Deformation mechanisms in nanocrystalline materials, and Prof. Farghalli A nanoscale softening Mohamed (FAM) • Modeling of deformation behavior Full Professor

• B.S. Cairo University Cairo, Significance: Egypt (1965) • M.S. University of California Investigation of mechanical behavior of materials is vital for two Berkeley (1970) primary reasons: • Ph.D. University of California Berkeley (1972) a) It contributes to the understanding of deformation mechanisms that are operative under certain conditions of Deformation map for micro, ultrafine, nano grained materials variables (stress, temperature, etc.) b) It leads to the development of reliable design criteria.

Key Publications: • F.A. Mohamed, “A dislocation model for the minimum grain size

obtainable by milling,” Acta Materialia, 51,4107 (2003).

• Yuwei Xun and F.A. Mohamed, “Superplastic Behavior of Zn-22%

Al containing nano-scale dispersion particles,” Acta Materialia, τ/G

52, 4401(2004). • F. A. Mohamed, “Interpretation of nanoscale softening Ni in

terms of dislocation accommodation boundary sliding,” Grain boundary sliding Metallurgical and Materials Transactions A, 38A, 340 (2007).

• Y. Cheng, M. Chauhan, and F.A. Mohamed,” Uncovering the mystery of Harper-Dorn creep in metals,” Metallurgical and

Materials Transactions 40A, 80 (2009). • F. A. Mohamed and H. Yang, “ Deformation mechanisms in nanocrystalline materials,” Metallurgical and Materials

Transactions A , 41A, 823 (2010). • F. A. Mohamed,” Deformation mechanism maps for micro- grained, ultrafine-grained, and nano-grained materials,” 16 Materials Science Engineering A, 526, 1431 (2011). Using Atomic Force Microscopy in measuring Grain boundary sliding Mohraz Lab Colloid Science and Complex Fluids Engineering [email protected] http://csl.eng.uci.edu

Research Summary: The Colloid Science Laboratory at UC Irvine investigates a range of fundamental and applied problems related to the physics and engineering of soft materials, colloidal dispersions, and complex fluids. Using state-of-the-art experimental techniques, our goal is to gain a more thorough understanding of how the interparticle interactions, particle geometry, and the suspension physicochemical conditions can be exploited to engineer novel micro- and nanostructured materials from multiphase colloidal suspensions. The applications of our research are broad, ranging from nano-structured composites for fuel cells and batteries to pharmaceutical formulations, coatings, personal care products, foods, and oil industries. Current areas of focus are: • Microstructural determinants of nonlinear rheology in Prof. Ali Mohraz colloidal gels and glasses. Assistant Professor

• Self-assembly and dynamics of colloidal particles at • B.S. Chemical Engineering, fluid/fluid interfaces. Azad University (1996) • Rheology of structured fluids in confinement. • M.E. Chemical Engineering, • Interfacial routes to microstructured materials synthesis. The City University of New York (1999) • Ph.D. Chemical Engineering,

Key Publications:

• Lee, M.N.; Chan, H.K.; Mohraz, A; Characteristics of Pickering Emulsion Gels Formed by Droplet Bridging,

Langmuir, DOI: 10.1021/la203384f (2012) (Cover Article) • Rajaram, B; Mohraz, A, Dynamics of shear-induced yielding

and flow in dilute colloidal gels, Physical Review E 84, 1, Art. No. 011405 (2011) • Lee, M.N.; Mohraz, A, Hierarchically Porous Silver

Monoliths from Colloidal Bicontinuous Interfacially Jammed Emulsion Gels, J. American Chemical Society 133, 18, 6945-

6947 (2011) • Lee, M.N.; Mohraz, A, Bicontinuous Macroporous Materials

from Bijel Templates, Advanced Materials 22, 4836-4841 (2010) (Inside Cover Article)

• Rajaram, B; Mohraz, A, Microstructural Response of Dilute Colloidal Gels to Nonlinear Shear Deformation, Soft Matter 6, 2246-2259 (2010)

• Pickrahn, K; Rajaram, B; Mohraz, A, Relationship between Microstructure, Dynamics, and Rheology in Polymer-

Bridging Colloidal Gels, Langmuir 26, 4, 2392-2400 (2010) 17 Mumm Lab Advanced Materials and Structures Laboratory [email protected] http://www.eng.uci.edu/users/daniel-mumm

Research Summary: Prof. Mumm's expertise lies in the area of advanced materials and structures. His primary research interests

involve the development of materials for power generation systems, propulsion, integrated sensing, advanced vehicle concepts and platform protection. His research efforts integrate high- resolution chemical and micro-structural characterization, novel

imaging and techniques, numerical simulations, mechanical testing, and thermo-mechanical exposure in order to understand, and ultimately control, the factors that influence the

performance and durability of complex structures and material systems. Prof. Daniel Mumm Associate Professor Current research efforts focus on: materials for fuel cells; • Ph.D. Materials Science and mechanics and reliability of nano-scale structures; coatings and composite materials for turbine engine systems; topologically Engineering, Northwestern cellular materials for lightweight multi-functional components and University. impact/blast/ballistic protection systems; and biologically-inspired morphing systems for maneuverability and propulsion. A common theme in all of these research efforts is the desire to understand the micro/nano-scale structures of interfaces between disparate materials, the evolution of those regions during component fabrication and in service, and the corresponding effects on the overall performance, durability and reliability of the system.

Key Publications: • AT Duong and DR Mumm. “Microstructural Optimization by Tailoring Particle Sizes for LSM-YSZ Solid Oxide Fuel Cell Composite Cathodes.” JOURNAL OF THE ELECTROCHEMICAL SOCIETY, 159: B40-B53 (2012). • MY Song, YJ Kwak, HR Park, DR Mumm. “Improvement in the hydrogen-storage properties of Mg by the addition of metallic elements Ni, Fe, and Ti, and an oxide Fe(2)O(3).” MATERIALS RESEARCH BULLETIN, 46: 1887-1891 (2011). • MY Song, IH Kwon, HR Park, DR Mumm. “Electrochemical properties of LiCo(y)Mn(2-y)O(4) synthesized using a combustion method in a voltage range of 3.5-5.0 V.” CERAMICS INTERNATIONAL, 37: 2215-2220 (2011).

18 Nilsson Lab UCI Nuclear Laboratory: Nuclear Fuel Cycles, Nuclear Security and Nuclear Medicine [email protected] http://www.eng.uci.edu/users/mikael-nilsson

Research Summary: Current research in our group emphasizes chemical processes for used nuclear fuel. The motivation is to reduce the hazard associated with the used nuclear fuel, to reduce the storage time needed for the material, and to reuse and recycle some of the useful raw material still existing in the spent nuclear fuel thereby improving the utilization of existing natural resources.

Our research involves:

1. Developing a fundamental understanding of the extraction processes to improve selectivity and efficiency. We are also working on extraction contactor studies to improve and Prof. Mikael Nilsson understand kinetics and fluid dynamics in typical equipment used for this work. Assistant Professor 2. Improvement in the remote monitoring of nuclear • M.S. Chemical Engineering, processes. Chalmers University of 3. The specific effect of radiolytic degradation of the chemicals Technology, Gothenburg, used in the process and how this effect can be addressed in Sweden. (2000) process calculations. • Ph.D. Nuclear Chemistry, 4. Preparation of radioisotopes for medical purposes. Chalmers University of Radioactive material can be used for a variety of purposes in medicine including cancer therapy, pain relievers and Technology, Gothenburg, imaging. Sweden. (2005)

Key Publications: • Pearson, J., Jan, O., Miller, G. E., Nilsson, M. “Studies of high linear energy transfer dosimetry by 10B(n,α)7Li reactions in aqueous and organic solvents”. Journal of Radioanalytical and Nuclear Chemistry, Online First, October 17 (2011). • Herbst, R. S., Baron, P., Nilsson, M. “Standard and advanced separation: PUREX processes for nuclear fuel reprocessing”. In K. L. Nash, G. J. Lumetta (Eds.), Advanced separation techniques for nuclear fuel reprocessing and radioactive waste treatment. 1st ed. Ch. 6. Woodhead Publishing Series in Energy: Number 2. (pp. 141-175). Cambridge, UK. Woodhead Publishing Limited, (2011). • Grimes, T. S., Nilsson, M., Nash, K. L. “Lactic Acid Partitioning in TALSPEAK Extraction Systems”. Separation Science and Technology, 45(12), 1725-1732, (2010). • Nilsson, M., Nash, K. L. “Trans-Lanthanide Extraction Studies in the TALSPEAK system: Investigating the Effect of Acidity and Temperature”. Solvent Extraction and Ion Exchange, 27(3), 354- 377, (2009). • Nilsson, M., Nash, K. L. “Review Article: A Review of the Development and Operational Characteristics of the TALSPEAK Process”. Solvent Extraction & Ion Exchange, 25(6), 665, (2007). 19 Nguyen Lab Computational Nanoscience of Biological Systems & Complex Fluids [email protected] http://compnano.eng.uci.edu

Research Summary: The overall goal of our research group is to elucidate the fundamental principles that govern the self-assembly and functionality of nanoscale biostructures using computer simulations. We apply the self-assembly principles gleaned from biological systems found in

Nature to the design and construction of novel self-assembling nanoscale biomaterials. Such nanoengineered biomaterials are expected to have a promising future in applications such as pharmaceuticals, drug delivery, tissue engineering, biomedical implants. We focus on five areas: 1. Exploitation of beneficial aspects of virus assembly for use in medicine and nanotechnology 2. Formulation of strategies to prevent protein aggregation Prof. Hung D. Nguyen especially the formation of ordered aggregates associated with Assistant Professor various neurodegenerative diseases and to promote protein • B.S. Chemical Engineering, aggregation for novel biomaterials University of Florida (1998) 3. Control of morphology of protein hydrogels for use in drug • M.S. Chemical Engineering,

delivery and tissue engineering North Carolina State U. 4. Design of functional DNA/RNA as novel biomaterials in (2000)

nanotechnology • Ph.D. Chemical Engineering, 5. Elucidation of the mechanism by which the genomic DNA North Carolina State U. content is packed via chromatin organization and regulated (2004) through histone biochemical modifications to modulate transcriptional gene expression in

Key Publications: • H.D. Nguyen, V.S. Reddy and C.L. Brooks III, “Invariant polymorphism in virus capsid assembly,” J. Am. Chem. Soc., 131(7): 2606-14 (2009) • H.D. Nguyen and C.L. Brooks III, “Generalized structural polymorphism of self-assembled viral capsids,” Nano Letters, 8(12): 4574-81 (2008) • H.D. Nguyen and C.K. Hall, “Molecular dynamics simulations of spontaneous fibril formation by random-coil peptides,” Proc. Natl. Acad. Sci. USA, 101(46): 16174-79 (2004)

Peptide aggregation in confinement

DNA hybridization Hydrogel nanofiber & self- assembly 20 Ragan Lab Self-Organization of Nanosystems [email protected] http://ragan-group.eng.uci.edu

Research Summary: In the Ragan laboratory, nanosystem fabrication and characterization is conducted to contribute to 1)

improving understanding of light-matter interactions for photovoltaics, plasmonics and metamaterial applications, 2) design of robust molecular sensors, and 3) improve design of selective and

active nanocatalysts for energy and industrial chemical conversion. Self-organization techniques are used to fabricate systems on

molecular length scales using methods that are easily translated into large-area production. Correlating physical properties with structure is conducted using scanning probe microscopy since Prof. Regina Ragan device performance is typically affected by surface defects and Associate Professor local composition. We have three main projects in the group: • B.S. Materials Science and 1. Metal nanostructures assembled in a periodic or cluster Engineering, University of architecture are fabricated to achieve near field enhancements for California, Los Angeles surface enhance Raman scattering (SERS) sensors and narrow band (1996) resonances for signal transmission and filtering. Correlations • M.S. Applied Physics, between optical properties and nanoarchitecture are investigated California Institute of to design and optimize structures. Technology (1998)

2. Tethered bilayer membranes (tLBM) that represent a • Ph.D. Applied Physics, simplified and versatile platform for cell membrane mimics are California Institute of Technology (2002) assembled on gold surfaces. This system is designed to measure protein-membrane interactions for biosensing and drug discovery applications. SERS Signal Enhancement 3. Fabrication and scanning probe microscopy atomic scale characterization of clusters of metal atoms on crystalline surfaces are combined with measurements of chemical activity in order to elucidate physical mechanisms that lead to higher activity and selectivity in nanoscale catalysts.

Key Publications: Optimized structure 1. “Design of a versatile chemical assembly method for patterning colloidal nanoparticles,” J. H. Choi, S. Adams, and R. Ragan Nanotechnology 20 (2009) 065301. 2. “A facile approach for assembling lipid bilayer membranes on gold electrodes” X. Wang. M. Shindel, S.-W. Wang, and R. Ragan Langmuir 26 (2010) 18239–18245 3. “Structural and Chemical Properties of Gold Rare Earth Disilicide Core-Shell Nanowires ” W. Ouyang, A. Shinde, Y. Zhang, J. Cao, R. Ragan, and R. Wu ACS Nano 5 (2011) 477.

21 Read Lab Dynamics of Complex Biochemical Systems [email protected]

Research Summary: The immune system is a vast network of cells, , and chemical messengers that monitors signs of disease

and defends the host against perceived threats. The complexity of these processes—they are multi-scale, nonlinear, and subject to

randomness at the molecular level—means that computer models are vital for uncovering mechanistic principles based on varied

experimental data. In the Read lab, our goal will be to elucidate immune system dynamics and regulation through theory and simulation of the biochemical reaction networks underlying

immune functioning. A major focus will be predicting interventions Prof. Elizabeth Read that can alter immunological behavior in order to treat or prevent Assistant Professor disease. Specific areas include:

1. Regulation of T cell immunity. T cells (essential players in immune • B.A. Chemistry and responses) become ineffective after chronic stimulation. Elucidating Mathematics, University of how the immune system balances positive and negative signals will Colorado (2003) identify strategies for reversing T cell dysfunction in chronic • Ph.D. Chemistry, University infections and cancer. of California, Berkeley 2. Selection of targets by the immune system. An immune response (2008) is often mounted against a small subset of pathogenic molecular signatures, out of many potential targets. Determining what controls this selection process will have applications for vaccine design.

3. Escape from immunity. Many viruses and tumors readily mutate to escape immune responses. We are investigating how immune pressure shapes fitness landscapes and drives evolutionary dynamics and disease progression.

4. Transition paths in complex systems. Understanding how th e

immune system processes information and transitions betwee n states requires advanced computational tools to treat complex ,

stochastic dynamics. We will develop efficient path-sampling tools for applications in multi-scale biological systems.

Key Publications: 1. “Stochastic effects are important in intra-host HIV evolutio n even when viral loads are high,” E. L. Read, A. A. Tovo-Dwyer, A.K. Chakraborty (in revision, 2012). 2. “Effects of thymic selection of the T-cell repertoire on HL A class I-associated control of HIV infection ” A. Kosmrlj*, E . L. Read*, Y. Qi, T. M. Allen, M. Altfeld, S. G. Deeks, F. Pereyr a, M. Carrington, B. D. Walker, A. K. Chakraborty Nature 465 (2 010) 350–354. 22 Shi Lab Opto-Electronics Integration and Packaging [email protected] http://www.eng.uci.edu/users/frank-shi

Areas of Research Interest:

• Optoelectronic Packaging 1. High Power White LED Technologies for lighting and backlighting 2. Fiber-Optic Packaging

• Optoelectronic Device and Packaging Materials

1. Novel rare earth doped materials for high power lasers Prof. Frank Shi and phosphors for white LEDs Full Professor 2. Silicone encapsulant 3. Die attach conductive materials for high power LEDs 4. Conductive pastes for solar cells and other devices • Ph.D., California Institute of 5. Nano-composite conductive and dielectric materials Technology (1992) • Joined the University of • IC Packaging and Manufacturing California, Irvine, in 1992

Professor Shi was honored by IEEE-CPMT Full story Society in 2010 as the recipient of

Outstanding Sustained Technical Contribution Award, “...Dr. Shi is being recognized for his accomplishments in multiple IEEE CPMT fields including optoelectronic packaging technology development; device and packaging materials development; electronic packaging and manufacturing technology development; and his leadership in the technology transfer of these various The product of a partnership between engineer Frank Shi developments from a research environment (pictured) and urologist Ralph Clayman: silicone materials to an industrial commercialization and formulated for optoelectronic devices (foreground) now production environment. Dr Shi's work will be used for breakthrough medical device applications. spans more than 15 years and is well disseminated in greater than 130 refereed Key Publication: publications in key industry journals, • Mondal, SK; Mitra, A; Singh, N; Shi, F; Kapur, numerous presentations and conferences.” P. “Ultrafine Fiber Tip Etched in Hydrophobic Polymer Coated Tube for Near-Field Scanning Prof Shi was elected to be an IEEE Fellow in Plasmonic Probe.” IEEE TECHNOLOGY 2011. LETTERS, 23: 1382-1384 (2011).

23

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Wang Lab Nanostructured Biomaterials [email protected] http://wanglab.eng.uci.edu

Research Summary: The fabrication of novel structures and functional systems at the nanometer-scale is currently an area of

enormous potential, but many challenges exist in synthesizing systems at such small sizes. In contrast, biological systems in nature have been highly successful in this endeavor. My research focuses on designing

functional nanosystems using a biomimetic approach. Nature-inspired macromolecular structures, capable of self-assembling into higher

architectures of nanometer- and micron-sizes, are the basis upon which we engineer new types of materials and fabrication strategies. The detailed control that provides in defining the Prof. Szu-Wen polymeric architecture of proteins, which can be coupled with Wang synthetic strategies to further extend functionality, is advantageous for creating highly-defined and uniform systems. Associate Professor • B.S. Chemical My research aims to understand the relationship between Engineering, University of molecular organization and material characteristics of Illinois (1993) biomacromolecular systems, and to use this understanding to design • M.S. Chemical biomimetic materials with novel properties. Among the specific Engineering, Stanford research topics under investigation by my group are protein complexes University (1994) for molecular transport, drug delivery, and vaccine development; novel • Ph.D. Chemical collagen-based biopolymers for therapeutics and tissue engineering; Engineering, Stanford and molecular strategies for endotoxin removal. University (1999)

Key Publications: • D. Ren, F. Kratz, S.-W. Wang. “Protein Nanocapsules Containing

Doxorubicin as a pH-Responsive Delivery System.” Small. 7(8):1051- 1060 (2011). • M. Shindel, D. Mumm, S.-W. Wang. “Biotemplating of Metallic

Nanoparticle Arrays Through Site-Specific Electrostatic Adsorption on Streptavidin Crystal .” Langmuir. 26(11):11103-11112 (2010). • S.W .P. Chan, S.-P. Hung, S. Raman, G.W. Hatfield, R. L athrop, N. A. Streptavidin crystal Da Silva., S.-W. Wang. "Recombinant Human Collagen a nd monolayer Biom i metic Variants Using a De Novo Gene Optimized for Modular Asse mbly." Biomacromolecules. 11(6):1460-1469 (201 0).

Breast cancer cell s treated with Collagen- and without nan oparticles mimetic polymer

Polymer-functionalized protein nanoparticles 25 Yee Lab Nanotechnology using Polymers [email protected] http://afyg.eng.uci.edu/

Research Summary: The research on nanotechnology is motivated by the development of complex micro- and nano- electronic, photonic and biomedical devices, which require the integration of many layers and channels comprised of different materials. A major tool we use is a nanoimprinter that allows us to reproduce features as small as 30 nm using polymers. The group has developed the reversal imprinting technique which uniquely allows the imprinting of 3-dimensional nanostructures and for imprinting on substrates that are not flat. The substrate may be a silicon wafer, glass, or a polymer film. By using inking Prof. Albert Yee technique that we have also developed, metal films, electrodes, Chair and Professor nanospheres, etc., may also be patterned on an imprinted nanostructure. Other nano-sized functional elements such as • B.S. Chemistry, University of nanowires may also be grown from these patterns. California, Berkeley (1967) • Ph.D. Chemistry, University The research on physical and mechanical behavior of of California, Berkeley polymers currently focus on the relaxation and deformation of (1971) nanostructures that we have fabricated. Because the size of polymer molecules may actually be larger than these nanostructures, interesting and unexpected relaxation behavior have been observed. The deformation and fracture of polymeric nanostructures are also expected to be quite different from those of bulk materials. These studies will have significant impact on the design and application of polymeric nanostructures to devices. An emerging area of research is to use nanotexturing to control wettability of polymer surfaces and cell adhesion.

Using nanoimprinting to create nano-structures for various Key Publications: applications including 1. Kong YP, Chen L, Yee AF, Probing near-surface nanoscale interactions with cells and mechanical properties of low modulus materials using a quartz tissues. crystal resonator atomic force microscope. Nanotechnology 22,

295709, 2011. 2. Peng, HG, Kong YP, Yee AF, Relaxation Kinetics of Peptide Nanostructures on Polymer Surface: Effect of Stress, Chain Nanopillars Mobility, and Spatial Confinement. Macromol 43, 409, 2010. 3. He CB, Liu, Liu TX, Tjiu WC , Sue HJ, Yee AF, Microdeformation and fracture mechanisms in polyamide-6/organoclay

nanocomposites. Macromol 41, 193, 2008.

26 Affiliated Faculty in Chemical Engineering & Materials Science: Joint Appointments

• James Brody, . Research: Single • John Lowengrub, Mathematics. Research: molecule dynamics, , functional , Microstructured materials, such as emulsions and surface plasmon resonance polymer blends, crystals, thin films and metallic alloys, • Zhongping Chen, Biomedical Engineering. Research: blood and biological tissues Biomedical photonics, microfabrication, biomaterials, and • Marc Madou, Mechanical and . biosensors. Fiber-optic based biomedical imaging systems Research: Miniaturization science (MEMS and NEMS) development with emphasis on chemical and biological applications • Ayman Mosallam, Civil and Environmental Engineering. • William Cooper, Civil and Environmental Engineering. Research: Structural and with a Research: Carbon cycling in natural waters, the treatment specialization in advanced composites and hybrid and, fate and transport, of pharmaceuticals in water, and, systems for infrastructure applications the development of ozone as a treatment process in • Reginald M. Penner, Chemistry. Research: Analytical ballast water of ships to prevent the spread of invasive chemistry; materials chemistry species • Peter Rentzepis, Chemistry. Research: Picosecond • Steven George, Biomedical Engineering. Research: time-resolved x-ray diffraction and EXFAS to determine Physiological modeling, computational methods, tissue the structures of ultrashortlived intermediates in engineering chemical and biological reactions in liquids; • Stanley Grant, Civil and Environmental Engineering. subpicosecond kinetics to probe non-linear phenomena Research: Environmental engineering, coastal water of molecules used for 3D optical storage and electronic quality, coagulation and of colloidal switching contaminants; environmental • Diego Rosso, Civil and Environmental Engineering. • Zhibin Guan, Chemistry. Research: Synthesis of new Research: Environmental , carbon generation of biomaterials for gene/drug delivery and footprint analysis, wastewater treatment, water and tissue regeneration. energy nexus, energy efficiency • G. Wesley Hatfield, Microbiology and Molecular . • Timothy Rupert, Mechanical and Aerospace Research: Computationally optimized DNA assembly Engineering. Research: Nanocrystalline metals and (CODA) and translational engineering technologies for the alloys, thin film materials, and the study of interfaces at self-assembly of synthetic genes for optimal protein the atomic level expression in non-native organism • Suzanne B. Sandmeyer, Biological Chemistry. Research: and of retro- • Jered Haun, Biomedical Engineering. Research: Targeted drug delivery, clinical cancer detection, nanotechnology, transposons and metabolic engineering in budding , computational simulations yeast • Kenneth Shea, Chemistry. Research: Developing new Michelle Khine, Biomedical Engineering. Research : Single • methods and strategies for synthesizing carbon-carbon Cell Electroporation, Shrinky-Dink Microfluidics, bonds Microsystems for Stem Cell Differentiation, Canary on a • Lizhi Sun, Civil and Environmental Engineering. Chip, Quantitative Single-Cell Analysis of Receptor Research: Micro/nano-mechanics of heterogeneous Dynamics and Chemotactic Response on a Chip composite materials, with applications for civil, • Matt Law, Chemistry. Research: nanoscale materials and mechanical, aerospace, electronic, and biomedical devices, solar energy conversion engineering • G.P. Li, and Computer Science. • Lorenzo Valdevit, Mechanical and Aerospace Research: High-speed semiconductor technology, micro- Engineering. Research: Mechanics of materials and electro-mechanical systems (MEMS) technology, opto- structures electronic devices, and the design, fabrication and testing • H. Kumar Wickramasinghe, Electrical Engineering and of integrated circuits Computer Science. Research: DNA sequencing • Wendy Liu, Biomedical Engineering. Research: Cell and techniques, nanotechnology

tissue engineering, biomaterials, microfabricated technologies, mechanotransduction Full list 27 Student Life at UCI

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28 Student Life at UCI

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29 Graduate Student Housing

Palo Verde is a graduate Organic community Barbeque grills and picnic community with 652 gardens are available for tables are available for apartments green thumbs residents

Student Housing Website

Map

Verano Place is a graduate and family apartment community, housing 1,220 students (many with families) in 862 apartments

Vista del Campo, privately Also provided: a resort style You can walk or owned community located swimming pool, jacuzzi, movie bike to school in on the campus, offers theater, game room, fitness perfect year- furnished apartments center, and computer lab round weather 30

5 miles away from the Pacific Ocean

Check the weather in Irvine!

31 Tour of UC Irvine Campus and Surrounding Communities

• UC Irvine Campus • City of Newport Beach • City of Irvine • City of Huntington Beach • City of Laguna Beach • Orange County

Laguna Beach

Newport Beach

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Huntington Beach

Many co o l things to do aro und O range Co unty…. 32 Applying to UC Irvine

Why choose Chemical Engineering & Materials Science at Admission Information UC Irvine?

• Innovative graduate program to study • Cutting edge multi-disciplinary research in Biotechnology, Energy, Microstructured Materials, Information for and Nanotechnology Prospective Graduate • Distinguished faculty and outstanding facilities Students • Competitive fellowship packages are available to outstanding applicants interested in Ph.D. degree programs Fellowships & Awards The recommended deadline for fall applications is January 15, especially for candidates who wish to be considered also for financial support. After this date, applications will be accepted on a rolling basis for a limited time. Apply Now!

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