Nanotechnology Nanobiotechnology, Optoelectronics, Nanocomposites, Nanostructures, Mechanical Properties, Corrosion, Materials Processing
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(MBR) Technology for Wastewater Treatment and Reclamation: Membrane Fouling
membranes Review Membrane Bioreactor (MBR) Technology for Wastewater Treatment and Reclamation: Membrane Fouling Oliver Terna Iorhemen *, Rania Ahmed Hamza and Joo Hwa Tay Department of Civil Engineering, University of Calgary, Calgary, AB T2N 1N4, Canada; [email protected] (R.A.H.); [email protected] (J.H.T.) * Correspondence: [email protected]; Tel.: +1-403-714-7451 Academic Editor: Marco Stoller Received: 14 April 2016; Accepted: 12 June 2016; Published: 15 June 2016 Abstract: The membrane bioreactor (MBR) has emerged as an efficient compact technology for municipal and industrial wastewater treatment. The major drawback impeding wider application of MBRs is membrane fouling, which significantly reduces membrane performance and lifespan, resulting in a significant increase in maintenance and operating costs. Finding sustainable membrane fouling mitigation strategies in MBRs has been one of the main concerns over the last two decades. This paper provides an overview of membrane fouling and studies conducted to identify mitigating strategies for fouling in MBRs. Classes of foulants, including biofoulants, organic foulants and inorganic foulants, as well as factors influencing membrane fouling are outlined. Recent research attempts on fouling control, including addition of coagulants and adsorbents, combination of aerobic granulation with MBRs, introduction of granular materials with air scouring in the MBR tank, and quorum quenching are presented. The addition of coagulants and adsorbents shows a significant membrane fouling reduction, but further research is needed to establish optimum dosages of the various coagulants/adsorbents. Similarly, the integration of aerobic granulation with MBRs, which targets biofoulants and organic foulants, shows outstanding filtration performance and a significant reduction in fouling rate, as well as excellent nutrients removal. -
Biopharma PAT Quality Attributes, Critical Process Parameters & Key
Biopharma PAT Quality Attributes, Critical Process Parameters & Key Performance Indicators at the Bioreactor May 2018 White Paper: Biopharma PAT Quality Attributes, Critical Process Parameters & Key Performance Indicators at the Bioreactor Table of Contents PAT Building Blocks .................................................................................................... 3 PAT for Biopharma ...................................................................................................... 5 Culture & Fermentation Process Types ....................................................................... 6 Monitoring Methods .................................................................................................... 8 Critical Process Parameters ...................................................................................... 10 Critical Quality Attributes & Key Performance Indicators ........................................... 14 Recent Applications of In-situ VCD & TCD ................................................................ 17 Conclusions .............................................................................................................. 19 References ................................................................................................................ 20 Focus Spots Intelligent Arc Sensors for pH and DO in-situ Measurement...................................... 10 Dissolved Oxygen User’s Experiences ...................................................................... 11 In-situ Cell Density -
Stachytarpheta Cayennensis Aqueous Extract, a New Bioreactor Towards Silver Nanoparticles for Biomedical Applications
Journal of Biomaterials and Nanobiotechnology, 2019, 10, 102-119 http://www.scirp.org/journal/jbnb ISSN Online: 2158-7043 ISSN Print: 2158-7027 Stachytarpheta cayennensis Aqueous Extract, a New Bioreactor towards Silver Nanoparticles for Biomedical Applications Francois Eya’ane Meva1,2* , Joel Olivier Avom Mbeng1, Cecile Okalla Ebongue1,3, Carsten Schlüsener2, Ülkü Kökҫam-Demir2, Agnes Antoinette Ntoumba4, Phillipe Belle Ebanda Kedi4, Etienne Elanga1, Evrard-Rudy Njike Loudang1, Moise Henri Julien Nko’o1, Edmond Tchoumbi1, Vandi Deli1, Christian Chick Nanga1, Emmanuel Albert Mpondo Mpondo1, Christoph Janiak2 1Department of Pharmaceutical Sciences, Faculty of Medicine and Pharmaceutical Sciences, University of Douala, Douala, Cameroon 2Institute for Inorganic Chemistry and Structural Chemistry, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany 3Clinical Biology Laboratory, General Hospital of Douala, Douala, Cameroon 4Department of Animal Biology and Physiology, Faculty of Science, University of Douala, Douala, Cameroon How to cite this paper: Meva, F.E., Abstract Mbeng, J.O.A., Ebongue, C.O., Schlüsener, C., Kökҫam-Demir, Ü., Ntoumba, A.A., Kedi, This study reports the preparation and characterization of silver nanopar- P.B.E., Elanga, E., Loudang, E.-R.N., Nko’o, ticles synthesized by the mediation of the plant weed Stachytarpheta cayen- M.H.J., Tchoumbi, E., Deli, V., Nanga, C.C., nensis through solution method. Ultraviolet visible spectroscopy (UV-Vis) Mpondo, E.A.M. and Janiak, C. (2019) Sta- chytarpheta cayennensis Aqueous Extract, a determines the presence of nanoparticles in the solution. Infrared spectros- New Bioreactor towards Silver Nanopar- copy (IR) proves organic molecules at the particles interface. Powder X-ray ticles for Biomedical Applications. Journal diffraction (PXRD) provides phase composition and crystallinity. -
Bioreactor Studies of Heterologous Protein Production by Recombinant Yeast
BIOREACTOR STUDIES OF HETEROLOGOUS PROTEIN PRODUCTION BY RECOMBINANT YEAST by ZHIGEN ZWNG A thesis presented to the University of Waterloo in fulNlment of the thesis quinment for the degree of Doctor of Philosophy in Chernical Engineering Waterloo, Ontario, Canada, 1997 @ Zhigen Zhang 1997 National tibrary Bibliothi?que nationale l*l dm, du Canada Acquisitions and Acquisitions et Bibliographie Services seMces bubriographiques 395 wellaStreet 395, me wdtingtori OrtawaON KIAW ûtiawaOlJ K1AûN4 Canada Canada Va#& Voinciilline, avm Nom- The author has pteda non- L'auteur a accordé une licence non exclusive licence dowiug the exclwe permettant il Ia National Ijiiiof Canada to Bibliothèque nationale du Cadade reproduce, 10- disttibute or sell reprodnire, *, distn'buerou copies of bis/her thesis by any means vendre des copies de sa thése de and in any fonn or fomLaf making qyelqy manière et sous quelque this thesis avaiiable to interested forme que ce soit pour mettre des persofls- exemplaires de cette thèse à la disposition des persornes intéressées. The auîhor retains owndpof the L'auteur conserve la propriété du copyright m Merthesis. Neither droit d'auteur qui protège sa thèse. Ni the thesis nor substsmtial extracts la thèse ni &s extmits substantiels de fiom it may be printed or otherwiSe celleci ne doivent être imprimés ou reproduced with the author's autrement reproduits sans son permission. autorisalian, nie University of Waterloo requin% the signatures of ali pesons using or photocopying this thesis. Please sign below. and give address and dite. ABSTRACT Fundamend enginee~gstudies were carried out on heterologous protein production using a recombinant Saccharomyces cerevisiae sPain (C468fpGAC9) which expresses Aspergillus mamon glucoamylase gene and secretes glucoamylase into the extracellular medium, as a model system. -
Biological Engineering (BIOE)
2021-2022 Academic Catalog BIOE3100 METABOLIC ENGINEERING BIOLOGICAL ENGINEERING An engineering approach to microbiology and bio-based products. As bioengineering continues to grow as a discipline, biomanufacturing (BIOE) using "microbial cell factories" continues to pique the interests of the entrepreneur. Commodity compounds, from amino acids to BIOE2000 FUNDAMENTALS OF BIOLOGICAL ENGINEERING biopolymers, can be manufactured fermentatively. With a growing This course introduces students to the fundamental concepts of list of organismal genome sequences available for analysis and Biological Engineering. Knowledge of thermodynamics and fluid manipulation, organisms ( mainly microorganisms) will be utilized and mechanics is critical for students to solve biological engineering subsequently manipulated by the growing number of molecular biology problems. Students will learn about energy, entropy and enthalpy in their and synthetic biology techniques available. Students will utilize the various forms in a biological setting. Students will also learn basic fluid methods and concepts taught in this course for problem solving in statics and dynamics. These topics will be applied in assignments, exams biotechnology, biomanufacturing and the biopharmaceutical fields. and in the laboratory to solve biomedical and biochemical engineering This course discusses cellular and organismal metabolic networks and problems. Case studies are presented to allow student to put together the mathematical and experimental manipulation of those networks. their -
Guide to Biotechnology 2008
guide to biotechnology 2008 research & development health bioethics innovate industrial & environmental food & agriculture biodefense Biotechnology Industry Organization 1201 Maryland Avenue, SW imagine Suite 900 Washington, DC 20024 intellectual property 202.962.9200 (phone) 202.488.6301 (fax) bio.org inform bio.org The Guide to Biotechnology is compiled by the Biotechnology Industry Organization (BIO) Editors Roxanna Guilford-Blake Debbie Strickland Contributors BIO Staff table of Contents Biotechnology: A Collection of Technologies 1 Regenerative Medicine ................................................. 36 What Is Biotechnology? .................................................. 1 Vaccines ....................................................................... 37 Cells and Biological Molecules ........................................ 1 Plant-Made Pharmaceuticals ........................................ 37 Therapeutic Development Overview .............................. 38 Biotechnology Industry Facts 2 Market Capitalization, 1994–2006 .................................. 3 Agricultural Production Applications 41 U.S. Biotech Industry Statistics: 1995–2006 ................... 3 Crop Biotechnology ...................................................... 41 U.S. Public Companies by Region, 2006 ........................ 4 Forest Biotechnology .................................................... 44 Total Financing, 1998–2007 (in billions of U.S. dollars) .... 4 Animal Biotechnology ................................................... 45 Biotech -
Pharmaceutical Review
Pharmaceutical Review Pharm. Bioprocess. (2013) 1(2), 167–177 Single-use bioreactors for microbial cultivation Single-use bioreactors are commonly used in the biopharmaceutical industry today, Nico MG Oosterhuis*1, Peter however, they are mostly limited to mammalian cell culture processes. For microbial Neubauer2 & Stefan Junne2 processes, concepts including the CELL-tainer® technology provide comparable 1CELLution Biotech BV, Dr AF oxygen mass transfer such as in stirred tank reactors. Data obtained with 15 and Philipsweg 15A, 9403AC Assen, The Netherlands 120 l working volumes indicate excellent performance with Escherichia coli and 2Chair of Bioprocess Engineering, Corynebacterium glutamicum cultures. Therefore, this type of single-use bioreactor is Institute of Biotechnologie, Technische applicable in biopharmaceutical processes, and also in a seed train for bulk chemicals Universität Berlin, Germany production such as amino acid production. It is expected that single-use technologies *Author for correspondence: will be applied ever more frequently in microbial-fed batch cultivation processes in E-mail: nico.oosterhuis@ cellutionbiotech.com combination with improved monitoring and control. Single-use bioreactors (SUBs, also often re- for cultivation of plant cells [1] . A step towards ferred to as disposable bioreactors) are nowa- innovation was achieved by the release of the days widely applied in the biopharmaceutical first single-use wave-mixed bioreactor for the industry. The scale is not restricted to labo- cultivation of shear-sensitive cells by Singh in ratory use, as reactors with working volumes 1999 [2]. The wide spread of the technology up to the m³-scale exist and can also be used has led to numerous optimiz ations and dif- for good manufactur practice processes. -
Undergraduate Handbook
Department of Chemical and Biological Engineering Undergraduate Handbook Academic Year 2021-2022 Revised: June 2021 Engineering Biology Certificate Bioengineering & Biotechnology Engineering & Sustainable Entrepreneurship Environmental Management Energy Certificate Studies Certificate Certificate Certificate Energy & Entrepreneurship Environmental & Management Technology The Chemical and Biological Engineering Materials Science Applied Math Certificate Major Certificate Materials & Optimization, Product Dynamics & Engineering Information Engineering Physics Technology Certificate Science & Engineering for New Technologies Table of Contents WHAT IS CHEMICAL AND BIOLOGICAL ENGINEERING? .................................... 2 THE EDUCATION OF A CHEMICAL AND BIOLOGICAL ENGINEER ........................ 3 CERTIFICATE PROGRAMS .............................................................................. 19 INDEPENDENT WORK ................................................................................... 20 GRADUATION REQUIREMENTS ..................................................................... 24 ACADEMIC HONORS ..................................................................................... 24 HONOR SOCIETIES, AWARDS, AND PRIZES .................................................... 25 ADVISING ..................................................................................................... 28 EXTRACURRICULAR ACTIVITIES ..................................................................... 29 POST GRADUATION PLANS .......................................................................... -
Dr. Junghae Suh to Be Inducted Into Medical and Biological Engineering Elite
For further information, contact Charlie Kim Director of Membership & Operations [email protected] February 15, 2021 Dr. Junghae Suh to be inducted into medical and biological engineering elite WASHINGTON, D.C.— The American Institute for Medical and Biological Engineering (AIMBE) has announced the election of Junghae Suh, Ph.D., Vice President; Professor, Gene Therapy Accelerator Unit, Biogen to its College of Fellows. Dr. Suh was nominated, reviewed, and elected by peers and members of the College of Fellows for significant contributions in synthetic virology and biomolecular engineering to design gene delivery technologies for controlled drug delivery. The College of Fellows is comprised of the top two percent of medical and biological engineers in the country. The most accomplished and distinguished engineering and medical school chairs, research directors, professors, innovators, and successful entrepreneurs comprise the College of Fellows. AIMBE Fellows are regularly recognized for their contributions in teaching, research, and innovation. AIMBE Fellows have been awarded the Nobel Prize, the Presidential Medal of Science and the Presidential Medal of Technology and Innovation and many also are members of the National Academy of Engineering, National Academy of Medicine, and the National Academy of Sciences. A formal induction ceremony will be held during AIMBE’s 2021 Annual Event on March 26. Dr. Suh will be inducted along with 174 colleagues who make up the AIMBE Fellow Class of 2021. For more information about the AIMBE Annual Event, please visit www.aimbe.org. AIMBE’s mission is to recognize excellence in, and advocate for, the fields of medical and biological engineering in order to advance society. -
CALL for PAPERS IEEE Transactions on Nanobioscience Thematic Issue: “Nano/Molecular Medicine and Engineering”
CALL FOR PAPERS IEEE Transactions on Nanobioscience Thematic Issue: “Nano/Molecular Medicine and Engineering” The IEEE Transactions on Nanobioscience will devote a themed issue “Nano/Molecular Medicine and Engineering” to a collection of papers highlighting research and technology development in the field of nano-biotechnology, molecular engineering, micro/nano-fluidics, micro/nano-system integration, nano-biology and nano-medicine. IEEE Nanotechnology Council is sponsoring the 9th IEEE International Conference on Nano/Molecular Medicine and Engineering (IEEE-NANOMED 2015) held on November 15–18, 2015, Honolulu, HI, USA to foster interaction between physicians, scientists, engineers in these emerging areas. Areas of interest include but are not limited to: • Nano and molecular technologies in medical theranostics • Nanotechnology in drug delivery • Biomedical imaging • Bio/nano sensing • Biochips and Bio-MEMS • Biomechatronics • Biological interface • Cells at the nanoscale • Nanomaterials for tissue engineering and biology • Frontiers in nanobiotechnology • Translational medicine Submissions are solicited from conference participants and other researchers in the field for a review paper or a research paper for this themed issue. Manuscripts will be subject to the normal peer review procedures of the IEEE Transactions on Nanobioscience. Follow the guideline (http://tnb.embs.org/forauthors.html), and submit your paper to Manuscript Central at http://mc.manuscriptcentral.com/tnbembs, indicating in the cover letter that you wish the paper to be considered for the Special Issue “Nano/Molecular Medicine and Engineering”. Submission deadline: July 15, 2016 Anticipated publication: November, 2016 Please address all other correspondence regarding this special issue to the Guest Editors: Jin-Woo Kim, Ph.D. Professor, Biological Engineering, Biomedical Engineering, Nanoscience & Engineering University of Arkansas, USA Email: [email protected] Deok-Ho Kim, Ph.D. -
Nanotechnology Applications for Food and Bioprocessing Industries
nd M y a ed g ic lo i o n i e B Trujillo et al., Biol Med (Aligarh) 2016, 8:3 DOI: 10.4172/0974-8369.1000289 ISSN: 0974-8369 Biology and Medicine Research Article Open Access Nanotechnology Applications for Food and Bioprocessing Industries Luis E Trujillo1*, Rodrigo Ávalos1, Silvana Granda1, Luis Santiago Guerra1 and José M País-Chanfrau2 1Industrial Biotechnology and Bioproducts Research Group, Universidad de las Fuerzas Armadas (ESPE), CENCINAT, Ecuador 2Universidad Técnica del Norte (UTN), Avenida 17 de julio, 5-21 y General José María Córdoba. CP 199, Ibarra, Imbabura, Ecuador *Corresponding author: Luis E. Trujillo, Industrial Biotechnology and Bioproducts Rearch Group, Universidad de las Fuerzas Armadas (ESPE), Ecuador, Tel: +81-3-5800-8653; Fax: +81-3-3811-6822; E-mail: [email protected] Received date: March 18, 2016; Accepted date: May 10, 2016; Published date: May 16, 2016 Copyright: © 2016 Trujillo LE, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited. Abstract Nanoscience is an emerging technology today with great application in different fields. Biocatalysts design, identification of different bacterial strains, monitoring the quality of food by different biosensors, food packaging with smart systems, active, intelligent and nano-encapsulation of bioactive food compounds are examples of some of these applications in the food industry. In this paper, some topics related to the potential of nanotechnology in the food industry are updated. In addition, some concerns about nanotechnology application in this popular industry are also discussed. -
Bioreactor Systems Are Essentially Required for Stem Cell Bioprocessing
Precision and Future Medicine 2019;3(1):19-23 REVIEW https://doi.org/10.23838/pfm.2018.00128 ARTICLE pISSN: 2508-7940 · eISSN: 2508-7959 Bioreactor systems are essentially required for stem cell bioprocessing 1 2 3 Jae Min Cha , Min-Young Lee , Jongin Hong 1 3D Stem Cell Bioprocessing Laboratory, Department of Mechatronics, Incheon National University, Incheon, Korea 2 Smart Healthcare & Device Research Center, Research Institute for Future Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea 3 Department of Chemistry, Chung-Ang University, Seoul, Korea Received: September 19, 2018 Revised: October 14, 2018 Accepted: October 16, 2018 ABSTRACT As stem cell technologies have rapidly advanced, the stem cell therapy market has been Corresponding author: Jae Min Cha forecast to reach hundreds of millions of USD in market value within the next 5 years. 3D Stem Cell Bioprocessing Regulatory frameworks throughout the stem cell market have been concurrently estab- Laboratory, Department of lished, which will encourage the advent of a variety of stem cell products in our society. Mechatronics, Incheon National Given the circumstances, stem cell bioprocessing has emerged as one of the most criti- University, 119 Academy-ro, cal fields of research to address a number of issues that currently exist in manufacturing Yeonsu-gu, Incheon 22012, clinical-grade stem cells at an industrial scale. Highly specialized bioreactor designs are Korea at the center of essentially required technologies in the field of stem cell bioprocessing, Tel: +82-32-835-8686 which ultimately aim for automated, standardized, traceable, cost-effective, safe, and E-mail: [email protected] regulatory-compliant manufacture of stem cell-based products.