FALL 2008

SightThe Wilmer EyeLine Institute at Johns Hopkins

We’re BeatGonna Trachoma Sheila West is on a mission and making significant research advances on the way. as see it contents

INSIGHT 4 Because Mentors Matter Thanks to Stephen J. Ryan and other donors, the assistant chief of service has more time to teach.

SPOTLIGHT The Shape of 6 Things to Come Wilmer’s new home for out- patient surgery and research promises to be an inspiring Dear Wilmer Family, destination.

This year we are witnessing the tangible emergence of ON THE COVER our newest building. Built We’re Gonna Beat entirely with philanthropic 10 Trachoma dollars, this beautiful struc- Sheila West and colleagues ture, Wilmer’s fourth building, will set a new standard for vision have set their sights on eradi- research and ophthalmic surgery. We are counting down the days cating a neglected cause of to our move-in next summer. pain and blindness. Recently, the press has been full of articles on “sustainable philanthropy.” In traditional philanthropy, a donor supports a good cause, such as giving eyeglasses to the poor; once the funds are de- EYE TO EYE pleted, the program ends. In sustainable philanthropy, donations act A Donation Funds as seed funds, establishing a self-supporting enterprise that benefits 14 Time to Learn others long after the initial funds are used. The Aliki Perroti Scholarship Created with $3 million from grateful patients and foundations, unites two women with a pas- the Wilmer Eye Institute is a perfect example of sustainable philan- sion to change the status quo. thropy. Last year, we provided more than $2.7 million in uncompen- sated care — plus eye surgery for the poor, funded by an endowment. We now annually provide care to the Baltimore region’s indigent worth about what it cost to create the Institute! We can absorb this EYE TO EYE loss because of the payments we receive from insurers and patients Twice Blessed With who do pay for our care, and because our doctors are willing to ac- 16 His Family’s Name cept lower salaries than they typically would receive out in practice. The son of a Wilmer surgeon Yet demand outstrips supply, and providing eye care to the indigent becomes the first to hold a and working poor in our community represents a major challenge for professorship established to Wilmer. We are not alone. The U.S. Census Bureau reported that, in honor his father. 2007, 45.7 million Americans had no health insurance. We who work at Wilmer are pleased to be able to help as many people as we do. We know how gratifying it is to care for those whose ANNUAL REVIEW only way of repaying us is the joy they experience when they see. Visionaries 18 The FY08 donors, faculty My best wishes. and residents who continue to make Wilmer one of the Peter J. McDonnell, M.D. world’s preeminent eye insti- William Holland Wilmer Professor and Director tutions.

2 SightLine FALL 2008 insight contents Sowing the Seeds WILMER IN THE NEWS of Discovery In every one of the 19 years that U.S. News & World Report has been ranking the nation’s Director’s Discovery Fund best hospitals and specialty recipient Noriko Esumi care, the Wilmer Eye Insti- is taking aim at genetic tute has been in mechanisms that may the top tier of underlie retinal disease. ophthalmology programs. As the magazine’s editors said in their 2008 and other important genes in the RPE “America’s Best might contribute to age-related macu- Hospitals” edi- lar degeneration. tion, “any good On recommendation from hospital should Wilmer’s senior faculty, Director Peter be able to handle everyday McDonnell recently awarded Esumi procedures and conditions,” seed money from the Institute’s Direc- but the patient who’s the tor’s Discovery Fund. target of the rankings is the McDonnell says the fund provides one “who truly needs out- him with monies to use as “venture standing care.” capital,” investing in young professors’ And that, of course, has futures. been Wilmer’s mission from “With increased competition for day one. We’re as proud as s a pediatric oncologist in external funding, often people with we have ever been of our Japan, Noriko Esumi became brilliant ideas lack the resources to impressive showing in this Afrustrated treating children explore them,” McDonnell says. “Dr. survey year after year, and with leukemia and other cancers Esumi is a particularly brilliant, young of the outstanding faculty, because of the gap between physicians’ assistant professor. The implications nurses and staff who consis- understanding about basic biological of her research are enormous, with the tently put us there. mechanisms and what was happen- potential to dramatically change how ing in her patients’ bodies. Now, as a we think of some retinal diseases.” molecular biologist at Wilmer, she’s Esumi says since some of her Na- determined to flesh out the genetic un- tional Eye Institute funding has been derpinnings of macular degeneration. cut due to federal budget pressures, Her research focuses on regulation the gift is essential to growing her own of gene expression within the retinal research group by hiring technicians pigment epithelium (RPE), a layer to help conduct some of the labora- of cells that nourishes and supports tory experiments. light-sensing mechanisms within the “This will dramatically accelerate retina. Esumi already has defined the pace of discovery in my labora- some regulatory mechanisms of a gene tory,” Esumi says. “As a young faculty Meet the Wilmer called VMD2, which, when mutated, member at Wilmer, I am incredibly development team: causes a disorder called Best disease grateful to those donors who have Danielle Grepps , Kim that threatens central vision. She plans helped create the Director’s Discovery Morton, Suzy Williams to build on that by further exploring Fund, and to my senior faculty who and Elizabeth Bower. how abnormal regulation of VMD2 have confidence in my abilities.” ■ Not pictured is Liz Griffin.

3 insight Because Mentors Matter

tephen J. Ryan credits his chief residency at Wilmer in 1969 as being the key and foundation to his successful career in ophthalmol- ogy. Now Ryan, president of the SDoheny Eye Institute in Los Angeles, is giving back through a named endowment fund to help support a new generation of chief residents, currently referred to as the assistant chiefs of service. “Dr. Ryan is one of Wilmer’s most famous alums,” says Wilmer Director Peter McDonnell. “He left Hopkins to become the first full-time chair of ophthalmology at the University of Southern California—as the only full-time faculty member—and built what was a low-profile department into one of the top programs in the country if not the world. Then he was prevailed upon to become dean of USC’s medical school. His whole career has been about medical educa- tion, mentoring, and inspiring others to rise to the next level.” The Wilmer assistant chief of service has long been a highly respected and demanding Stephen Ryan position. The ACS not only is a practicing always remembers clinician but also acts as an educator and role model 2003, he approached his his Wilmer roots. for medical students and residents. Historically, those former boss about head- who have held the position have become some of the ing a $1 million cam- nation’s leaders in the field. paign to create an endowment for the ACS. With Ryan wanted to ensure that the ACS could set Ryan’s personal and matched donations kick-starting aside time for mentoring the campaign, the goal was reached. the residents under his or Says Ryan, “Among the things that keep Wilmer her leadership. on top are its commitment to education and the About 10 years ago, strong support of the director. This endowment will Among the things Ryan approached former provide income to help the ACS carry out the mission Wilmer Director Morton of educating the great group of Wilmer residents.” that keep Wilmer Goldberg about helping A celebration and inaugural naming will occur on top are its support the position and May 1, 2009, with Ryan, a trustee of Johns Hopkins began making donations Medicine and member of the Johns Hopkins Society commitment to toward that end. Then, of Scholars, in attendance. when McDonnell (anoth- “We strive, year after year, to identify someone education and the er former assistant chief who, like Dr. Stephen Ryan, clearly embodies the strong support of of service and former qualities and skills that make for a strong leader USC faculty member) and an excellent clinician, teacher and role model,” the director. returned to Wilmer in McDonnell says. ■

4 SightLine FALL 2008 Selfless Colleague

hen Ruben “Over three Adler, an On May 16, Paton, right, presented “The Virtue Wacknowl- decades, his wise of Eye-Magination: Creativity and the Medical Mind,” as edged world leader Wilmer’s second Susruta Lecture in History and Ethics in vision research, counsel was an of Ophthalmology. The Wilmer assistant chief of service learned that he might under Edward Maumenee, Paton is the founder of be terminally ill, one invaluable resource Project ORBIS, a nonprofit that provides ophthalmology of the first things he to three directors education and care in developing countries. It is the did was meet with generous support of V.K. Raju, left, and his wife, Rani, Wilmer Eye Insti- of the institute,” that has made the Susruta Lectureship a new tradition tute Director Peter at Wilmer. Raju is president of the Eye Foundation of McDonnell. Adler says McDonnell. America and a clinical professor of ophthalmology at wanted to make sure West University. that the work of the young postdoctoral students and fellows in his institute lab would not be disrupted by his death. “He was remarkably selfless,” says McDonnell. “He was a dream faculty member. If all Hopkins faculty were like him, you wouldn’t need department chairs. He had a great sense of the whole and was heavily invested in the success of his colleagues.” Adler, the first Arnall Patz Distinguished Professor of Ophthalmology, died on Dec. 31, 2007. He was 68. A native of Argentina, Adler received his medical degree from the University of Buenos Aires School of Medicine in 1963. He moved to the United States in 1977 and joined Wilmer in 1982. He became a professor of ophthalmology and neurosciences in 1991 and was named the first holder of the Patz professorship in 1993. Adler was deeply interested in preventing and treat- ing retinal diseases. Among his many contributions to eye research was his participation in the discovery of CNTF, a unique neurotrophic factor. He was the first to hypothesize that such growth factors could play a key role in the prevention and treatment of photoreceptor degenera- Ruben Adler tions. He and his colleagues at Wilmer’s Retinal Degeneration Center were pioneers in the development of tissue culture methods for retinal photore- ceptors. The center has used an extensive array of cellular and molecular techniques to probe the effects of genetic and micro-environmental fac- tors on these retinal cells. ■

FALL 2008 SightLine 5 The Shape of Things to Come “Noble life demands a noble architecture for noble uses of noble men.” – Frank Lloyd Wright John Safer, left, and Morton Goldberg discuss the Lucite maquette, or model, of Quest

he anticipation is, literally, building. Just one year after ground-breaking festivi- ties marked the turning Tpoint between vision and reality, the Wilmer Eye Institute’s emerging new home for outpatient surgery and research is making a strong statement. For those who will occupy the space, that statement, in every sense of the word, is light. Slated to open next summer, the 207,000-square-foot structure ris- ing on the corner of Broadway and Orleans Street was conceived not only as an ultra-modern center where more than 14,000 people annually can receive sight-sparing operations from Wilmer’s world-renowned surgeons. It’s also been designed to fast-track discoveries that are far more likely to happen when clinicians, geneticists, biochemists, molecular biologists, epi- demiologists and surgeons—all bent on curing blinding eye diseases—can bounce ideas off each other by simply strolling to the lab next door. Cure may be a bold goal indeed, but the scores of men and women whose gifts are providing 100 per- cent of the funding for construction understand exactly what’s at stake. Named for its lead donors, the Robert H. and Clarice Smith Building and the Maurice Bendann Surgical Pa- vilion of the Wilmer Eye Institute at Johns Hopkins testify to the quality

FALL 2008 SightLine 7 The will combine graceful lines that will blend with the surrounding architecture, with an of care Wilmer pa- Schein for cataract surgery as well. As a upward thrust that tients have always result of these operations, says Safer, he’s received. been able to continue his work. Thank- would symbolize the Morton Gold- ing Goldberg and McDonnell for recent unending struggle berg, Wilmer’s well-wishes they sent, the sculptor wrote, former director “the best birthday present is that I can for knowledge and who has dreamed read the card.” and labored over So when Goldberg suggested that a understanding that is the plans for this Safer sculpture would be just the thing to building for over adorn Wilmer’s new building, the octo- the essence of research. a decade, sees a genarian agreed to create what will be – John Safer unifying theme: an unforgettable tribute to all who carry Wilmer’s donors on the Institute’s mission of seeking new grasp only too well knowledge in the battle against vision loss. what it means to Named Quest, Safer’s design is a 35- face the prospect of life robbed of sight. foot flame of polished steel that will stand Robert Smith’s mother-in-law, for ex- near the building’s Broadway entrance in ample, was treated at Wilmer for macular the five-story, light-flooded T. Boone Pick- degeneration, the leading cause of blind- ens Atrium. Its undulating lines, which ness in U.S. adults over the age of 55. Goldberg likens to a strand of DNA, So too was a man whose contribution also set the stage for other architectural of artwork will be so breathtaking that, elements being incorporated throughout in Goldberg’s words, “this building will the building, such as echoing curvilin- be unique, not just at Johns Hopkins, ear shapes in the terrazzo that will run but in Baltimore. It will be a destina- the length of the atrium’s first floor. The tion.” John Safer, like so many of those six-ton sculpture will rise on a circular ter- who turn to Wilmer for hope, learned razzo plinth that Safer and chief building a decade ago that architect Adam Gross designed together. the culprit behind And that’s just the beginning. Works his then-failing by building namesake Clarice Smith, an vision was macular acclaimed painter of modern life who’s degeneration. The exhibited both nationally and interna- world-renowned tionally, will add grace and warmth to artist—who was the building’s main level. Meanwhile, described by art paintings by esteemed New York artist critic Frank Getlein Wolf Kahn, known for blending realism as “a monumental and Color Field in what’s been called a sculptor in the tra- fusion of color, spontaneity and repre- dition of Phidias, sentation, will enliven the clinic area. Michaelangelo and “Robert Smith wanted this to be Rodin”—was oper- a building that people would always ated on by Gold- remember,” says Wilmer Director Peter Quest begins berg for his AMD McDonnell, “and every inch has been to come alive and later needed thought through to the nth degree, from at a foundry in the skill of Wilmer the architectural competition at the start Lancaster, Pa. eye surgeon Oliver to the most recent gift from the Smiths IN RECOGNITION OF THEIR GENEROUS DONATIONS

$10,000,000 & Above $5,000,000 - 9,999,999 $1,000,000 - 4,999,999 $500,000 - 999,999 $100,000 - 49,999

Mr. & Mrs. Heather & Advanced Mr. & Mrs. Maurice Alcon Medical Optics William T. Bendann James P. Gills Jack Kay Young, Jr. Trust Henry & Ruth Beatrice T. Boone Pickens Shirley Blaustein Cummings Gouaux Rosenberg Foundation Foundation Mayer Sandy & Rick Guerrieri Drs. Peter Charles E. Smith Family Leonard Forsythe Cohen & Jan Family Foundation Foundation McDonnell

Samuel B. Lincy Arlene & & Margaret Robert H. Foundation Robert Kogod C. Mosher & Clarice Smith Foundation William R. & Jacqueline & James Ralph S. Norma Kline O’Connor Tiefel McDonagh

Joseph Albert & & Harvey Stephanie Therese Turner Meyerhoff & Marshall Family Charitable Fund Wishnack Fund

Those who’ve made the building of mature trees that will be planted creation of these commonsense clinical above the possible will be outside. It will be both an inspiring, neighborhoods defines the very es- floor will play honored in the beautiful environment and a space sence of the new research floors. off the gleam- William R. and built to increase efficiency and maxi- “There was a time,” explains Mc- ing planes Norma Kline mize interactions among our research- Donnell, “when brilliant people work- of the Safer Tiefel Lobby. ers and surgeons.” ing alone made the important discov- sculpture, the For patients, who will park just eries. Today, we need the intersection glass curtain outside and enter through welcoming of many disciplines: genetics, public walls of the labs and the glass rails of glass doors on the building’s south- health, biochemistry. The challenge the grand staircase, the atrium embod- west side, the surgical experience will we’ve had with our older buildings is ies the very idea of breakthrough. It no longer involve the time-wasting that we’d put a senior investigator in takes center stage between the offices moves between rooms and floors now one place because it was available but lining every level along the east wall required in Wilmer’s century-old origi- then we’d have to put junior investiga- and the research labs on the west, all nal building. Instead, patients will be tors working on related research in placed to promote walking around and guided in a logical flow from the spa- other places because we had no adja- what McDonnell calls the “unplanned cious entrance and registration area, to cent space. Some of our faculty could interactions” so likely to launch new nearby pre-op rooms, to 21st-century go for months, even years, without ideas and understanding of the myriad operating rooms designed with all even seeing each other.” causes of blindness. suspended equipment—including No more. Researchers working in For John Safer, there could be no operating microscopes and teaching the Smith Building will arrive through better place to display Quest. videography—to keep the floors free the northeast entrance, angled precisely “The sculpture,” he says, “will of obstacles. Recovery rooms, which toward the Wilmer dome and sheathed combine graceful lines that will blend can also double as pre-op rooms if in reflecting glass to mirror its emi- with the surrounding architecture, need be, are sited near a separate exit nence in the history of modern oph- with an upward thrust that would to the parking lot so patients won’t thalmology. They’ll cross the octagonal symbolize the unending struggle for have to retrace their path through the vestibule with its bluestone pavers knowledge and understanding that is building once they’re discharged. and pass through the William R. and the essence of research.” ■ “We’ll be able to do 50 percent Norma Kline Tiefel Lobby, where the more procedures per day,” says Mc- main leadership wall honors the donors Not To Be Missed Donnell, “because everyone—surgeons, whose generosity has made everything The two-day building dedication, set nurses, staff—will be right next to each possible. And then, turning left, they’ll to coincide with the 80th anniversary other. Each operation will take much enter the sun-drenched atrium. of Wilmer’s first dedication, will take less time and, as a result, the experience Spanning the building from the place October 15-16, 2009. Festivities will be far more patient friendly.” north end to the south, where light will include a formal dedication, day of That same thinking underlying the pouring in from skylights five stories science and community celebration.

FALL 2008 SightLine 9 We’re Gonna Beat Trachoma

Armed with $12.1 million courtesy of the Bill & Melinda Gates Foundation, Sheila West and a far-flung cohort of colleagues are doing battle with the world’s leading infectious cause of blindness—and they’re aiming to win. FALL 2008 SightLine 11 to fund her research. “Unlike the National Institutes of Health, which is largely in- terested in the impact of dis- eases in the United States, the Bill & Melinda Gates Foun- dation considers operational research for the global burden of disease,” she says. That includes what’s known as “neglected tropical diseases,” such as leprosy, lymphatic Sheila West and filariasis, schistosomiasis and her colleagues trachoma. “By themselves, were doing a these are not the killers that survey in Tanzania he blonde woman in the West will focus malaria and HIV are, and when a little boy photos wears a denim on improv- for that reason are neglected. wandered over jumper and a plain T-shirt. ing known But taken together, they’re and offered her She is surrounded by Afri- treatments for responsible for considerable some peanuts. can women and children, trachoma, which morbidity,” explains West. Tsmiling widely and swathed in brightly include surgery She hopes her research will colored clothing. The landscape appears and antibiotics. find enough overlap in con- parched and dusty, and in some shots Trachoma is trol of these diseases so that you can see children shouldering enor- the world’s leading infectious cause of medical treatments may rid communi- mous water jugs. Back in Sheila West’s blindness. The disease is now a prob- ties not just of trachoma, but possibly office at the Wilmer Eye Institute, lem mainly in Africa, the Middle East co-existing conditions as well. those scenes seem as remote as the sub- and parts of Asia—places where clean The Gates Foundation responded Saharan villages West visits regularly to water and access to medical care are to West’s approach, which focuses on treat people infected with trachoma, a seriously lacking. Because trachoma improving known effective treatments blinding eye disease that affects some is easily spread via flies, clothing and for trachoma. Although West shies 84 million people each year. bedding, children in particular are away from the word cure, she will say, In 2007, West was awarded a infected over and over again. These “We can eliminate blinding trachoma, five-year, $10 million grant from the prolonged episodes lead to scarring but we need some answers before we Bill & Melinda Gates Foundation to of the upper eyelid, which contracts can say that it’s going to be by 2020 uncover ways to eliminate trachoma. the lid and causes the eyelashes to [the goal set by the WHO]. That’s In October 2008, the Foundation rub across the cornea. “It’s not only where the grant came in.” gave her an additional $2.1 million, painful, but leads to corneal blind- Specifically, the Gates grant will allowing West to expand her research ness,” explains West. And it’s largely tackle two aspects of the four-pronged to include other neglected tropical irreversible. “These eyes that are blind treatment approach endorsed by the diseases. Working with a consortium from trachoma are not good candi- WHO, known as the SAFE strategy: of researchers from the Wilmer Eye dates for corneal transplants, even if the S stands for surgery to correct the Institute, where she is a professor of such a technology were available in in-turned eyelashes; A is for antibiot- ophthalmology; ’s School of these countries, and it’s largely not.” ics to treat the infectious community; Hygiene and Tropical Medicine; the Despite intense competition for F and E are for face-washing and University of San Francisco; and the grant money, West says it wasn’t diffi- environmental change, like the provi- World Health Organization (WHO), cult to convince the Gates Foundation sion of clean water, to try to interrupt

12 SightLine FALL 2008 the transmission of trachoma. generous dona- West’s team is concentrating on tion of the drug the S and A components. “Despite azithromycin, surgery that we know corrects lashes, or Zithromax, in a program setting we have a huge by Pfizer means problem of recurrence,” she explains. that communi- “We feel a lot of that is due to surgi- ties can now be cal technique.” With a shortage of treated with a ophthalmologists in rural Africa, the single-dose oral surgery is being performed by medi- pill or liquid—a cal assistants, ophthalmologic nurses huge advantage in and paramedical personnel, with less the fight against than ideal results. trachoma. In Tanzania, Part of the grant will fund a clini- West, who is Sheila West cal trial to determine whether a new fluent in French confers with device developed by Wilmer plastic and Swahili, has spent most of her in their commu- members of her surgeon Shannath Merbs will decrease 24-year Wilmer career “trooping nities. “I see a team and village the recurrence rate of trachoma. The around in these villages in Africa.” country of mo- residents. trial, slated to begin in 2009 in Tanza- Her work there has left some indelible tivated health nia, will follow 1,400 patients over two impressions that few other Americans professionals years. An enthusiastic West says, “It can imagine. “The kind of instabil- who work hard shows how you take a high-technology ity and horrific stories that the U.S. and bring pride to their job, whether area like plastic surgery, focus on a tends to see in Africa are so far from it’s sitting in an office doing data entry, problem in a third-world area, and my experiences,” says West. “I have whether it’s out in the field flipping come up with a new approach that people who have been with me since eyelids or trying to get Zithromax to nobody’s thought of.” 1986 in Africa. They are among the far corners of these villages.” West will also aim to answer the the hardest working people I have Part of what keeps West going are questions of how many people need ever encountered.” She knows many the impressive results of trachoma to be treated with antibiotics and how African ophthalmologists who have programs like hers. Follow-up surveys often in order to eliminate trachoma forgone international careers to devote to a Zithromax program in Ghana in highly affected communities. A themselves to improving the eye health revealed no evidence of trachoma— making it the first African country to essentially eliminate the disease. The Gambia will likely follow suit. “It’s PART OF THE JOB IS GETTING THERE happening,” says West. “We just need Seeing what can be medical care to these West estimates to speed up that process. done with even limited remote villages, and that $84,000 would “When I started out my career, resources gives Sheila West has raised funds buy another van plus trachoma was the second leading West hope for the rural for another van. How- insurance and extra cause of blindness worldwide; it was African communities ever, she could desper- parts that would deliver a huge problem in so many countries. where she works to ately use a third. “We antibiotics to an entire And I may actually be able to retire eliminate trachoma. The are just holding our district. when this is no longer a public health Gates Foundation has third vehicle together “Something as simple problem,” she says. “To know that provided her team with with baling wire and as that can make a huge I was part of an effort for the global one vehicle to bring duct tape,” she says. difference.” elimination of a blinding eye disease is truly exciting.” ■

FALL 2008 SightLine 13 eye to eye A Donation Funds Time to Learn

Improving health poulio Hospital in and boosting memory of her father knowledge have and her mother, Maria. long been the This modern, 285-bed philanthropic goals public hospital was built of Aliki Perroti. in an underserved Ath- ens neighborhood. With its highly skilled and dedicated medical and professional staff, the hospital provides needed health care across a broad spectrum of specialties to patients regardless of their financial means, and functions as a highly regarded and integral pillar of the health care system of —not unlike Johns Hopkins in its history and standing. Additionally, Perroti established and funded the Dimitris Perrotis College of Agricultural Studies at The American Farm School in Thes- soloniki, Greece, in memory of her husband, and the college’s state-of-the-art Aliki and Dimitrius Perrotis Library there which serves the Thessoloniki community as well as student and faculty needs. Long a friend of Johns Hopkins and a liki Perroti has long been recognized as a substan- grateful beneficiary of its services, Perroti has been par- tial private and public philanthropist in her native ticularly impressed with the Wilmer Eye Institute. Among Acountry. She is a daughter of Theodoros Koustanto- her most recent contributions to Johns Hopkins is fund- poulos, an internationally renowned civil engineer who was ing to establish the Aliki Perroti Scholarship at Wilmer. a major force in post-World War II Greece after his wartime She established the scholarship in gratitude for the care refusal to assist or cooperate with the Nazis during the and friendship of Walter Stark, director of the Cornea occupation resulted in the confiscation of his construction and Cataract Service. The Perroti Scholarship will support company and exposure to personal danger. bright young physician-scientists, like Kalliope Stasi, who Perroti established and solely funded the Konstanto- will train under Stark’s mentorship.

14 SightLine FALL 2008 Two women, united through their passion to push boundaries, help advance a way to reverse corneal damage.

lthough Kalliopi Stasi enjoyed Aliki Perroti caring for patients in her solo Scholarship Aophthalmology practice in recipient , Greece, she missed the labo- Kalliopi Stasi ratory research she’d enjoyed while is researching pursuing her doctorate. corneal “I yearned to advance patient regeneration. care by formulating and investigating new research questions based on my clinical cases,” she says. After spend- ing several years in the United States, training with some of the country’s leading eye centers, Stasi came to Wilmer in July for a clinical fellowship in cornea, cataract and refractive surgery under Walter Stark, director of the Cornea and Cataract Service. Now, as the recipient of the Aliki Perroti Schol- arship, Stasi’s salary will be supported for a year as she pursues a research project with Stark and Assistant Professor Roy Chuck, identifying and characterizing stem cells that have the potential to regenerate the surface of the cornea. Taken from the limbus (the eye’s white outer coating), “I look forward to introducing my dear friend, Mrs. these “mother cells” can develop the properties of cells that Perroti, to this year’s brilliant Perroti scholar, Dr. Stasi, line the outermost layer of the cornea. When that outer eye who has already shown so much promise in her work,” surface is destroyed, the corneal surface becomes cloudy or says Stark. “Mrs. Perroti has been a great champion for scarred and then cannot properly refract light, significantly excellence in medical education and research in her home affecting sight. The hope, says Stasi, is to isolate stem cells country as well from a patient’s healthy eye, grow them in culture, and as here at Johns transplant them to the damaged eye. Hopkins. We are The Perroti Scholarship also puts Stasi in a good position thrilled to have her Learn more about to apply for a National Institutes of Health K08 Mentored name forever linked supporting Wilmer Clinical Scientist Development Award, which helps student to the Wilmer In- at www.wilmer.org scientists become more successful with translational research. stitute name. ■ or please call 410-955-2020

FALL 2008 SightLine 15 eye to eye Twice Blessed With His Family’s Name

The son of a much-revered Wilmer surgeon becomes the first to hold a professorship established in his father’s honor.

ike many children, Nicholas Iliff wanted to pursue a career different from that of his father. Charles E. Iliff III, was considered one of the pioneers Lof oculoplastics, the surgical restora- tion of the function and appearance of the eye. While Nick’s older brother, W. Jackson Iliff, followed their father into ophthalmology, Nick decided to go into general surgery. Halfway through his internship in surgery at Johns Hopkins, though, he realized that pursuing a specialty just for the sake of being different from Dad wasn’t a good enough reason. His true love was indeed ophthalmology. Perhaps this is not so surprising for a boy who grew up watching home movies of his fa- ther’s eye surgeries and listening to him discuss his work at the dinner table. In May 2008, Nick became the inaugural recipient of the Charles E. Iliff III, M.D., Professorship in Surgi- cal Ophthalmology. The endowed professorship was made possible in part by Helen J. Iliff, a retired pediat- ric cardiologist who also goes by her professional name, Helen Ossofsky. Helen, an alumna of the Johns Hopkins Oculoplastics University School of pioneer Medicine, desired that Charles Iliff her stepson, Nick, be

16 SightLine FALL 2008 He’d go to the hardware store and everyone would call him Doc. He was a the first recipient of the professorship Charles’ friendly demeanor named for her late husband and estab- earned him the respect and affec- special person. lished to give back to the place that, tion of his patients and his com- she says, “shaped [her] life.” munity, says Nick. “He’d go to At the Wilmer Eye Institute, the the hardware store and everyone Iliff name is renowned. During his would call him Doc. He was a 50-year association with Wilmer, special person.” Charles Iliff became internationally It was these qualities that Helen not what he wanted to be known for” recognized for his groundbreaking wished to honor when she endowed or how his family remembers him, work in oculoplastics, cataract surgery the professorship in his father’s name, says Nick. and corneal transplantation. His career says Nick. “What Helen wanted and Per the donors’ wishes, the at Wilmer began in 1942, following the reason she wanted it was my father Charles E. Iliff III, M.D., Professor- his graduation from the Johns Hop- was this sort of interesting personality. ship in Surgical Ophthalmology is kins University School of Medicine He taught a lot about what it means specifically a clinical professorship, in 1939. Even after going into private to be a physician that transcended meant to support surgical work and practice, Charles maintained strong writing papers or doing research and teaching rather than lab research. The ties with Wilmer as an assistant, then some of the things that are so impor- permanent position will provide him associate, and finally full professor of tant and so much a part of Hopkins more time to teach residents and an ophthalmology in 1973. At the time and Wilmer.” While the late Dr. Iliff oculoplastics fellow, attend clinical of his death in 1997 at the age of 86, will certainly be remembered for meetings, and write, says Nick, as Charles was a professor emeritus of operations and instruments that he well as more flexibility and time with ophthalmology at Hopkins. pioneered—some of patients. “I’ve always spent the vast But the late Dr. Iliff was so much which his son still majority of my time on patient care, more than a list of impressive ac- uses today—“that’s so it wasn’t that I had to change what complishments, says his son Nick. I do,” he says. “He was extremely well-liked by Nick’s hope is that the everybody—colleagues, friends, professorship he now holds will family. And he cared tremen- provide continuity for future dously about his patients.” His members of the Wilmer com- father earned a reputation as munity. When he retires, the a surgeon who could handle position will go to the next seemingly hopeless cases. leader in eye surgery at Wilmer. “He was a very upbeat Growing up, he recalls hearing person, very much a his father talk about his col- can-do kind of person,” leagues and the early days of the says his son. Institute: “Not only the people “His patients who worked at Wilmer but the left feeling that Helen J. Iliff people who made Wilmer what it is their problems and Nicholas today. What they started really is in were solvable.” Iliff at the the fabric of what Wilmer is. And I Coupled with professorship think these professorships strengthen his superb dedication that fabric and make sure that that surgical skills, ceremony. continuity is there.” ■

FALL 2008 SightLine 17 annual review Our Work to Cure Blindness: Our Donors

Burlingame Foundation Dr. Daniel Finkelstein The scientists and staff of the Mr. Thomas D. Burns, Sr. The David & Barbara B. Hirschhorn Mr. and Mrs. Arthur Buslik Foundation Mrs. Charles A. Camalier, Jr. Mr. and Mrs. David T. FitzGerald Wilmer Eye Institute at Johns Mrs. Marie R. Cappiello Mr. George R. Floyd Mr. Edmund N. Carpenter II Mr. Dennis J. Flynn Hopkins gratefully acknowledge Mr. and Mrs. J. Thomas Carruthers, Jr. Flynn & Associates, Inc. Mrs. Patricia Castillo Fondazione AVF Rusconi our partners in philanthropy Mr. and Mrs. Frederick J. Cavanaugh Mr. William T. Forrester Cecilton Lions Charities, Inc. Forsythe Family Foundation Ms. Wilma L. Chaloupka The Francis & Miranda Childress listed below. The generosity of Mrs. Charlotte C. Chamberlain Foundation Mr. Clement Chen III Frederick J. Rosenau Foundation these friends supports a tradition Ms. Dorothy S. Chidester Mr. Ernest Freudman Mrs. Rose Cipriano Dr. David S. Friedman and Mrs. Clarence & Ida Klassen Foundation Elizabeth Lunt of collaboration and far-reaching Mr. and Mrs. Francis O. Clark The Funger Foundation, Inc. Clark Charitable Foundation Mr. Charles J. Gatchell investigation as, together, we Mr. Harold E. Clendenin Mr. and Mrs. William H. Gates III Mr. Carl C. Coe, Jr. Mr. William H. Gates and Ms. Helen pursue the complex challenges Mr. Leonard K. Cohen * E. Yuu Ms. Anita Cohen Mrs. Janet C. Gehrlein Mr. William K. Colbath Mr. and Dr. Nahum Gelber of eye diseases. While our space Mr. and Mrs. Richard Cole George & Theresa Laniado Fund Ms. Therese C. Collins Georgetown Lions Club District 22-D here is limited, our thankfulness is Mr. Michael Comenetz Drs. Philip V. and Marjorie W. Gerdine CoMentis, Inc. Ms. Lina Gerson Mrs. JoAnn Condry Mr. and Mrs. Carl S. Gewirz not. Although gifts of any amount Mr. Timothy Conley Dr. Howard D. Gilbert Dr. Mildred P. Cooper Mr. Irving Gilston are gratefully received, only gifts Ms. Donna L. Craig Mr. James H. Gipson Damascus Lions Foundation, Inc. Mrs. Catherine M. Gleeson * totaling more than $100 in the Mrs. Charlotte A. David Mr. and Mrs. Mrs. Jeffrey Goldberg Mrs. Betty Davidov Dr. Rufus C. Goodwin Mr. Bernard Davis Mr. and Mrs. Lloyd E. Goodwine fiscal year ending June 30, 2008, Mr. and Mrs. Richard Davison Gordon Foundation Mr. and Mrs. Theodore DeBois Ms. Shirley K. Gouaux * could be listed in this report. If Mr. John G. Dendrinos Mrs. Hill Graff Mr. and Mrs. John Detweiler Dr. and Mrs. Sandford D. Greenberg DeVito Family Trust Ms. Shirley M. Greene any donor was accidently missed, Ms. Cathy DiBernardo Mrs. Shirley K. Griffin Dietz, Gilmor & Associates APC Ms. Margaret V. Griffith please contact the development Mr. and Mrs. Steven Dola Mr. Willard Hackerman Ms. Dorothy V. Donaho Mr. and Mrs. Gary Hall office at 410-955-2020. Mr. William A. Donlon Mr. and Mrs. John L. Hammersmith Mr. William J. Dorman, Jr. Dr. Barbara Snyder Hawkins Ms. Clover E. Downs * Mr. George S. Hawn Mr. and Mrs. Edward DuCharme Hess Foundation, Inc. Anonymous (10) Mr. Thomas W. Barham Mr. and Mrs.* Thomas O. Duff, Jr. Ms. Dorothy A. Heyl Abraham Krasne Foundation Mrs. Priscillia F. Barrett Edward K. and Janet E. Dunn, Jr. Fund Hilb, Rogal and Hobbs Company Dr. Ingrid A. Adamsons Mr. Simon Barsky Mrs. Jean H. Durfee Mr. and Mrs. Gerald Hills Ms. Marilyn Adelson Mrs. Charlotte Bartizek Dr. Martin G. Edwards Mr. Randolph Hinz Al Saud Company, Ltd. Dr. Alycia J. Bartley-Heinsen El Sawy Family Foundation Mr. and Mrs. Michael D. Hobbs Alcon Research LTD Arnold and Mabel Elan Pharmaceuticals, Inc. Ms. Dorothy Holler * Alcon Research LTD Beckman Foundation Eliason Foundation Mr. and Mrs. David L. Holman Mrs. Nezhat Aliabadi Bentley Pharmaceuticals, Inc. Emanuel Gruss and Riane Gruss Mr. and Mrs. Peter M. Holt Alimera Sciences Mrs. Esther R. Birnbaum Charitable Foundation Dr. David P. Honey * Mr. Graham Allan Dr. William Robert Bitman Emmert Hobbs Foundation, Inc. Mr. and Mrs. Lawrence A. Horn Mr. and Mrs. Robert C. Anderson Mr. Geoffrey E. Bloom Eric Weinmann Charitable Trust Mr. Antoni Horodowicz Mr. and Mrs. Roland S. Arthur Mr. James D. Blum Ms. Maria Teresa Escalante Mr. James A. Hourihan Mr. Alan Astrove Anna Borun & Harry Borun EyeRx Research, Incorporated Howard & Martha Head Fund, Inc. Mrs. Virginia C. Atkinson Foundation Rear Adm. John N. Faigle Mr. Steve Hronec Dr. Lawrence Atkinson Ms. Nancy L. Boyce Faller Family, LLC The Hultquist Foundation Mr. and Mrs. William F. Baker, Jr. Mr. Robert E. Cook and Ms. Paula J. Ms. Patricia O. Farley Mrs. Mary S. Humelsine Mr. and Mrs. Richard P. Baks Brooks Mr. and Mrs. Robert B. Feduniak Mr. Craig B. Huston * Mr. H. Furlong Baldwin Mr. Bud Brylawski Mr. and Mrs. David Feldman Mr. Earl M. Hyde, Jr. Mrs. Harriet G. Bank Mr. William L. Buggie Mr. William Finglass Mr. Christopher Ihde

18 SightLine FALL 2008 Mrs. Helen J. Iliff Mr. Peter Luchsinger General and Mrs. John S. Patton Sony Pictures Entertainment Ms. Anne G. Imboden Mr. Robert G. Luedke Paul S. Bomberger Jr. Foundation Mr. and Mrs. Phillip Spector Mr. and Mrs. Roger Irvine Ms. Christina E. Luedke Mr. and Mrs. Herbert L. Peck Dr. and Mrs. Charles H. Spragg JJ Haines Foundation, Inc. Ms. Hazel M. Lyon Mr. Jay S. Pepose and Ms. Susan K. Mr. Frederick W. Stauffer Mrs. Joan C. Jackson Dr. and Mrs. Sidney Lyons Feigenbaum Ms. Lisa Steiner Jacob S. Shapiro Foundation Mr. and Mrs. John S. Magney Mr. Stephen T. Peterson Mr. and Mrs. Robert M. Stern Mr. and Mrs. David A. James Mr. Thomas J. Maholchic Mr. T. Boone Pickens Mr. and Mrs. William R. Stewart James Family Charitable Foundation Mr. Thomas Mammarella and Mrs. Mr. Rubin Plushner Mr. and Mrs. Howard F. Stirn James R. Phippard Foundation Barbara A. Marsh Dr. Irvin P. Pollack Mr. and Mrs. Bradley Stirn Dr. Robert S. Jampel Mr. and Mrs. Peter Marousek Mrs. Alice E. Pratt Mr. and Mrs. Robert M. Stroman Dr. William H. Jarrett II Mr. Andrew Marriott Primus Pharmaceuticals Strouse Family Fund Mr. Peter L. Jennings Ms. A. Kelsey Marshall Mr. Stephen B. Qually Ms. Marie E. Svensson Mr. and Mrs. Kenneth H. Johnson Marshall Family Fund Ms. Julie G. Quincey Dr. Janet B. Svirsky Mr. Thomas O. Jones * Mr. and Mrs. Stephen H. Maslen Mr. and Mrs. Stephen F. Raab The Swearingen Foundation Mrs. Catherine C. Jones Mr. W. Thomas Matthews Mr. and Mrs. Blair C. Ranneberger Ms. Edith J. Sweeney Mrs. Stacie L. Jones Mr. L. Stanley Mauger Ms. Joanne A. Rathman Dr. Harvey A. Sweetbaum Ms. Virginia M. Jordan Dr. William May Mr. and Mrs. Philip J. Rauch Mr. Robert Swendson Mrs. Gloria M. Joseph Mrs. Linda W. McCleary Raymond & Z. Valeere Sass Mr. and Mrs. John P. Swope Jr. Joseph E. and Marjorie B. Mr. and Mrs. Donald S. McClure Family Foundation Mr. Daniel Syed Jones Foundation Mr. Hugh P. McCormick, Jr. Mrs. Mary Jane B. Read Mr. Everett R. Terrell, Jr. Mr. Wayne S. Jostrand Capt. and Mrs. William M. McDonald, Dr. Charles W. Rector Theodore H. Barth Foundation Inc. Mr. and Mrs. Wolf Kahn USN, Ret. Mrs. Marilyn S. Reiner Dr. and Mrs. Richard J. Thomas Kalkin Family Foundation, Inc. Mr. Michael J. McGuigan Renah Blair Rietzke Family & Mr. W. Reid Thompson Kane Lodge Foundation, Inc. Dr. Edward N. McLean Community Foundation Mr. and Mrs. William R. Tiefel Mr. Marshall V. Kaplan Mr. John K. McNulty Jr. Dr. and Mrs. Charles B. Reuland Mrs. R. Carmichael Tilghman Mr. and Mrs. Allen Kayne Mr. and Mrs. John K. McNulty, Sr. Ms. Belle K. Ribicoff Mr. Trygve H. Tonnessen Mr. Roger M. Kelly * Mr. and Mrs. Patrick P. McNulty Richard J. Moriarty Charitable Fund Tracon Pharmaceuticals Inc. Ltc. Aus. and Mrs. Robert Mr. William M. McNulty, Jr. Mr. Norman C. Richter Transmolecular, Inc. D. Kennedy (Ret.) Medical Illness Counseling Center Mr. M. Delmar Ritchie, Jr. Mr. Glenn E. Tremper Kenney Family Foundation Mr. R. Donald Mellinger Robert & Gail Edelstein Foundation Tunmore-Conrad Fund Mr. John B. Kentch Dr. and Mrs. Joel David Meshulam Mr. and Mrs. Raymond C. Roberts Mr. and Mrs. Thomas E. Utz Dr. David L. Knox Mr. Ellsworth Messersmith Mr. and Mrs. Albert T. Robinson Mr. and Mrs. Steve Vagnerini Mrs. Marlene Koeppel Ms. Rebecca Meyers Dr. and Mrs. Dean J. Rodman Van Metre Family Foundation Inc. Mr. and Mrs. Robert Kogod Ms. Sylvia Michelson Ms. Barbara L. Rosenfeld Vascular Vision Pharmaceuticals Co. Kosberg Charitable Foundation Trust Dr. and Mrs. Albert T. Milauskas The Rothschild Charitable Foundation Mr. Gregg Viola Mr. and Mrs. Peter Kovner Dr. Redonda G. Miller Mr. Bill Rowley Vivian L. Smith Foundation Ms. Jean Kralka Ms. Anne W. Miller Mr. Alfred R. Rubin W. M. Keck Foundation Mr. and Mrs. Robert Kunisch, Sr. Mr. and Mrs. Rodney E. Milnes Mrs. Wanda S. Ruggiero Mr. Irmengard Wagstaff Mr. and Mrs. Raymond P. L. Kwok Mrs. Bettie R. Mintz Mr. and Mrs. Robert M. Runyan Mrs. Christine M. Wallace Mr. and Mrs. Samuel J. Lambert Milton Schamach Foundation, Inc. Ms. Hattie and Ms. Kathy Ruttenberg Mr. and Mrs. Stratford C. Wallace Mr. and Mrs. John P. Laurence Monica and Hermen Greenberg Dr. and Mrs. Stephen J. Ryan, Jr. Mr. Clarence Ward LaVale Lions Club Foundation Mr. and Mrs. Joachim Saal Mr. and Mrs. Peter A. Warner Mr. and Mrs. John Lavery Mrs. Rebecca P. Moon Dr. and Mrs. R. Bradley Sack Mr. Edward C. Watters III Dr. and Mrs. Richard G. Lazar Mr. and Mrs. Dennis M. Murphy Ms. Beverly S. Saffa-Stapleton Dr. and Mrs. Robert B. Welch Lazinsky-Comeq-Flamoltz Fund Dr. Kieran P. J. Murphy Salisbury Lions Club Ms. Addison Werner Ms. Lois Leach * Ms. Hattie Nalewaja Sangamo Biosciences Mr. and Mrs. John B. Wheeler Mr. and Mrs. L. Douglas Lee Mr. and Mrs. Daniel G. Nelson Mrs. Harold A. Schlenger William & Ella Owens Medical Mr. Alfred P. Leiserowitz Mr. Rick Nichita and Ms. Paula Mr. and Mrs. Jack W. Schnoor Research Foundation Mr. and Mrs. David M. Leive Wagner Mr. Arnold R. Schunick Mrs. Gertrude J. Williams Mr. and Mrs. Robert Levin Mrs. Agnes E. Nixon Mr. Alan Robert Schwartz and Mrs. Dr. Marjorie J. Williams John & Judith Brown Levy Fund Mr. Derek E. Nolan Debra D. Yogodzinski Mrs. Carol R. Wills Mr. Robert A. Lewis Notal Vision, Limited Ms. Nancy B. Schwartz Ms. Sarah Wilmer Dr. Robert Lewit Mr. and Mrs. Lawrence Nussdorf Ms. Evelyn P. Seidman Mr. and Mrs. Donald R. Wolfe Mr. and Mrs. John Linn Mr. Ralph S. O’Connor Mr. Robert G. Sharp Ms. Marcella E. Woll * Lions Club of Olney, Inc. Odd Fellows Grand Lodge of PA Mrs. Elisa F. Sharpe Mrs. Elizabeth B. Wood Lions of Georgia, Inc. District 18 Mr. and Mrs. Dale G. Odenwelder Ms. Harriet Sheridan Mr. and Mrs. James R. Wood Lockheed Martin Co. Dir. Char. Fund Ms. Carole A. Ortt Rose L. Shure Ms. Aleda C. Wright Ms. Dreama S. Lodge Mr. and Mrs. Ernest T. Oskin Sidney R. Rosenau Foundation Mr. A. Thomas Young Ms. Nicole M. Logan Othera Pharmaceuticals Inc. Dr. Beverly Judith Silver Dr. David S. Zee Mr. Francisco Lopes Filho Mrs. Selma L. Owrutsky Mrs. Lennie R. Slocumb Mr. and Mrs. Stuart Zimmerman Mr. and Mrs. George B. Lott, Jr. Dr. and Mrs. Lawrence C. Pakula Mr. and Mrs. Robert H. Smith Mr. and Mrs. Joseph C. Zuray Mrs. Katherine M. Loughlin Mr. David J. Paladino Ms. Melissa G. Smith Mr. and Mrs. Richard E. Lowder Mr. Michael B. Panitch Dr. Jean G. Smith * Deceased Mrs. Rita J. Lowenstein * Ms. Rose Parapiglia Mr. Harold Snyder Lubin and Meyer, P.C. Mr. Stephen B. Paras Dr. Ying Kin So and Ms. Mei Yang Ms. Lucille H. Lucas * Dr. David Paton Leung Ms. Deborah L. Lucas Mr. and Mrs. William J. Patterson, Jr. Mr. Sidney Sober

FALL 2008 SightLine 19 annual review Faculty Feats A sampling of FY08 honors for Wilmer physicians.

William R. Bitman Roy Chuck, M.D., Ph.D. IT Director the Tom Clancy Professor of Ophthalmology

• Publication: Bitman, WR • President, Chinese American Ophthalmological and Sharif, NA: Conceptual Society Framework for Ranking R&D • Golden Key and Golden Apple Awards for Projects. IEEE Transactions • Elected to the Johns Hopkins Medical School Council on Engineering Management. • Visiting professor, University of California San 2008; 5:267–278. Francisco; Washington University St. Louis; Indiana University; Boston University; Albert Einstein College of Medicine of Yeshiva University; Eye Center Michael Boland, M.D. and University; Sun Yat Sen Eye Center Guangzhou University; Al Tawam Hospital Johns Hopkins Interna- • Received an unrestricted gift from the Microsoft Be tional, Abu Dhabi, UAE; University of Pennsylvania Well Fund to be used to support research into using • Elected to the editorial boards of the Journal of a personal health record to improve patient adher- Refractive Surgery, Lasers in Surgery and Medicine, ence to medications Current Opinion in Ophthalmology • Appointed to the American Academy of Ophthal- mology Committee on Refractive Management and Diana V. Do, M.D. Intervention

• American Academy of Ophthalmology Achievement Award Lori Grover, O.D. • The Jean Lacerte Lecturer, Les Journees Ophtal- mologiques de L’Universite Laval (JOUL), Quebec, • Named chair of the AOA Low Canada Vision Rehabilitation Section

Henry Jampel, M.D., M.H.S. the Independent Order of Odd Fellows Professor of Ophthalmology Rahul Khurana, M.D. • Senior Achievement Award, American Academy of Ophthalmology • Ten Outstanding Young Americans Award

David L. Guyton, M.D. the Zanvyl Krieger Professor of Pediatric Ophthalmology

• Presented the John E. Brown Memorial Lecture, Jeremy Nathans, M.D. Ohio State University, titled “Strabismus Compli- cations from Local Anesthetics” • The 2008 ($1.4 million) • Mildred Weisenfeld Award, Association for Re- António Champalimaud search in Vision and Ophthalmology Vision Award, referred to as • Presented the Jules Stein Lecture, Jules Stein Eye Institute, UCLA, the “Nobel Prize for Vision,” titled “Changes in Strabismus over Time …” the largest monetary prize • Presented the third Eugene R. Folk, M.D. Memorial Lecture, Illinois in the field of vision and Eye and Ear Infirmary, titled “Ocular Torsion Reveals the Mechanisms one of the largest scientific of Cyclovertical Strabismus” prizes in the world

20 SightLine FALL 2008 James Handa, M.D. Susan B. Bressler, M.D. the Robert Bond Welch Professor of Ophthalmology the Julia G. Levy, Ph.D. Professor of Ophthalmology • Named the Robert Bond Welch Professor of Ophthalmology • Gertrude D. Pyron Award, • Named an editorial board member of Investiga- American Society of Retina Spe- tive Ophthalmology and Vision Science cialists (ASRS) • Named to “Best Doctors in America,” 2007–2008 • Named the Goodwin M. Breinin, • Named to “America’s Top Doctors,” 7th Edition, 2007 M.D. Visiting Professor, New • Named to “America’s Top Doctors for Cancer,” 4th Edition, 2008 York University Medical Center • Presented the Jeffrey Berger Memorial Lecture, Scheie Eye Institute, • Senior Honor Award, American Philadelphia Society of Retina Specialists • Keynote Speaker, University of California-Davis Ophthalmology Symposium, Napa Valley Harry A. Quigley, M.D. the A. Edward Maumenee Michael Grant, M.D., Ph.D. Professor of Ophthalmology

• Presented the keynote address, “Evidence-Based • Invited to give the prestigious Management of Orbital Fractures” at the third Jackson Lecture at the Ameri- AO European Advanced Symposium on Orbital can Academy of Ophthalmology Reconstruction, April 2008 (2009) • Elected a director of the American Society of • Elected president for a four-year Ocular Trauma term of the Glaucoma Research Society, an inter- national body of specialists in that disease

Peter Campochiaro, M.D. the George S. and Dolores D. Eccles Professor of Ophthalmology Teaching Awards Chosen by the Medical Students • Special Scholar Award, Research to Prevent Blindness Esen Akpek, M.D. Vivian Rismondo, M.D. Faculty Teaching Award Allan D. Jensen Part-Time Faculty Teaching Award Houman Hemmati, M.D. Emily W. Gower, Ph.D. W. Richard Green House Henry Wiley, M.D. Staff Teaching Award Best Fellow Teacher • Ernest & Elizabeth Althouse Nicholas T. Iliff, M.D. Scholar Award, Research to Best Attending Faculty Teacher Prevent Blindness

Peter J. McDonnell, M.D. Albert Jun, M.D., Ph.D. Director and William Holland Wilmer Professor of Ophthalmology • Inaugural Wilmer Pro- fessors Research Grant • Prof. Moacyr Alvaro Gold Medal for Outstanding Recipient ($100,000) Service, XXXI Congress of Ophthalmology, San Paulo, Brazil, March 2008 • Doheny Society of Scholars Induction and Medal, Doheny Eye Insti- tute, University of Southern California, Los Angeles, March 2008 • Susruta Lectureship, West Virginia University, May 2008

FALL 2008 SightLine 21 annual review

Quan Dong Nguyen, Walter J. 2007 M.D., M.Sc. Stark, M.D. the Boone Pickens Best Doctors • Senior Honor Award, Professor of Baltimore American Society of Retina Ophthalmology Specialists Magazine • Presented the Jean Lacerte • G.B. Bietti Lecturer, Les Journees Medal, Italian Neil M. Bressler, M.D. Ophtalmologiques de Society of Susan B. Bressler, M.D. L’Universite Laval (JOUL), Quebec, Canada Ophthalmology Peter A. Campochiaro, M.D. • Guest of honor and invited speaker, Macula: Roy S. Chuck, M.D. Advances in Diagnosis and Therapy (MAT), James P. Dunn, M.D. Torino, Stan Daniel Finkelstein, M.D. • Guest of honor and invited speaker, Jornadas Vinores, Ph.D. David S. Friedman, M.D. Nacionales de Oftalmologia, Annual Meeting John D. Gottsch, M.D. of the Argentinian Academy of Ophthalmol- • Invited keynote David L. Guyton, M.D. ogy and the third International Symposium of speaker for the James T. Handa, M.D. the Argentinian Society of Retina and Vitre- Conference of Nicholas T. Iliff, M.D. ous, and Uveitis, Buenos Aires the Argentine Henry D. Jampel, M.D., M.H.S. • Guest of honor and invited speaker, the Chapter of the Peter J. McDonnell, M.D. 27th meeting of the Mexican Retina Society, Association for Research in Vision Neil Miller, M.D. Acapulco and Ophthalmology (Investigación Harry A. Quigley, M.D. • Guest of honor and invited speaker, 2008 en Visión y Oftalmologia), Cor- Oliver D. Schein, M.D., M.P.H. meeting of the Korean Retina Society, Yonsei doba, Argentina, 2008 Sharon Solomon, M.D. University School of Medicine, Seoul • Invited keynote grand rounds Walter J. Stark, M.D. • Program director, the 2008 Uveitis Subspe- speaker at Boston University Jennifer E. Thorne, M.D., Ph.D. cialty Day, Annual Meeting of the American School of Medicine Robert S. Weinberg, M.D. Academy of Ophthalmology, Atlanta, Ga.

Michael X. Repka, M.D. David Zee, M.D. • Presented the Marshall M. Parks Lecture at the annual • Invited speaker meeting of the American of the German Academy of Ophthalmology Ophthalmology Society; the Neuroophthal- Jennifer E. Thorne, M.D. mology Society of Australia; Singapore National Eye Hospital; oculomotor research symposiums in Nantes, France, and in Seeon, Germany; the Pan • Special Scholar Award, Re- American ENT Congress in Quito, Ecuador; and the Barany Society in Kyoto search to Prevent Blindness • Appointed deputy director of the Coordinating Center Oliver D. Schein, M.D., M.P.H. for the Studies of Ocular the Burton E. Grossman Professor of Ophthalmology Complications of AIDS (SOCA) • Keynote speaker (James Key Lecture) at the biannual • Appointed to the AUPO Board of research meeting of the Contact Lens Association Managers for Fellowship Compliance of Ophthalmologists • Named to Best Doctors in America, • Appointed vice-chair for quality and safety, 2007–2008 Wilmer Eye Institute

22 SightLine FALL 2008 Philanthropy Summary Commitments include cash received and pledges made, life income gifts, Pledges grants, planned gifts, and bequests made during FY08. Gifts Capital Planned Gifts Current Programs New Grants

Endowment By Transaction Type By Use $ (Millions) % of Total $ (Millions) % of total Total Commitments $ 44.9 100% Total Commitments $44.9 100% Planned Gifts $20.1 44.8% Current Programs $25.3 56.3% New Grants $16.8 37.4 Endowment $17.1 38.1% Gifts $5.2 11.6% Capital (Building) $2.5 5.6% Pledges $2.8 6.2% 81 Hagerstown Manchester 16 We’re in your Westminster neighborhood

70 HOSPITALS Wilmer Eye Institute Wilmer Eye Institute at Green Spring Station Wilmer Eye Institute 95 at Johns Hopkins 83 at White Marsh Frederick 795 Wilmer Eye Institute Frederick at Johns Hopkins 11 695 Towson Bayview Medical Center 70 Wilmer Eye Institute Baltimore OUTPATIENT CENTERS at Frederick Wilmer Eye Institute at Johns Hopkins Wilmer Eye Institute 70 at Columbia Damascus 270 Wilmer Eye Institute Wilmer Eye Institute at Wyman Park Medical Center at Frederick Wilmer Eye Institute Wilmer Eye Institute at Green Spring Station 95 at Johns Hopkins Bayview Columbia Medical Center Wilmer Eye Institute at Odenton Wilmer Eye Institute Gaithersburg 97 at Columbia Wilmer Eye Institute at White Marsh 14 Laurel Odenton Wilmer Eye Institute at Wyman Park Medical Center Wilmer Eye Institute at Odenton Information & Referrals 410-955-5080 495 Annapolis Reston Toll-Free Directions Washington 877-477-9519 www.wilmer.org JHM Vienna Cedar Lane Falls Capital Church Heights Upper 395 Marlboro 66 Fairfax 95 495 Non-profit Org. SightLine U.S. Postage Paid Easton Springfield Baltimore, MD SightLine is published twice a year by the WilmerFort Eye Institute at Johns Hopkins. Permit No. 2589 Washington Managing Editor: Elizabeth Bower Editor: Mary Ann Ayd Contributing Writers: Mary BrandywineAnn Ayd, Karen Blum, Abigail Green 95 Designer: Vladimir Rajevac © The Johns Hopkins University 2008 10 Huntingtown To add/remove your name from the mailing list, please send your nameWhite and Plains address to: The Wilmer Eye Institute Sightline Subscription Cambridge 600 N. Wolfe Street, Wilmer 112 Baltimore, MD 21287-9015 [email protected] 410-955-2020 410-955-0866 (fax)

The mission of the Wilmer Eye Institute is to use and develop the finest scientific evidence to promote improved ophthalmic care and the reduction of visual disability in a collaborative enviroment that combines compassionate patient care, innovative research, and the training of future leaders in ophthalmology and visual sciences.