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University of Birmingham Uterotonic Agents for Preventing Postpartum University of Birmingham Uterotonic agents for preventing postpartum haemorrhage Gallos, Ioannis D; Williams, Helen M; Price, Malcolm J; Merriel, Abi; Gee, Harold; Lissauer, David; Moorthy, Vidhya; Tobias, Aurelio; Deeks, Jonathan J; Widmer, Mariana; Tunçalp, Özge; Gülmezoglu, Ahmet Metin; Hofmeyr, G Justus; Coomarasamy, Arri DOI: 10.1002/14651858.CD011689.pub2 License: None: All rights reserved Document Version Publisher's PDF, also known as Version of record Citation for published version (Harvard): Gallos, ID, Williams, HM, Price, MJ, Merriel, A, Gee, H, Lissauer, D, Moorthy, V, Tobias, A, Deeks, JJ, Widmer, M, Tunçalp, Ö, Gülmezoglu, AM, Hofmeyr, GJ & Coomarasamy, A 2018, 'Uterotonic agents for preventing postpartum haemorrhage: a network meta-analysis', Cochrane Database of Systematic Reviews, vol. 2018, no. 4, CD011689. https://doi.org/10.1002/14651858.CD011689.pub2 Link to publication on Research at Birmingham portal Publisher Rights Statement: Checked for eligibility:17/05/2018 Gallos ID, Williams HM, Price MJ, Merriel A, Gee H, Lissauer D, Moorthy V, Tobias A, Deeks JJ, Widmer M, Tunçalp Ö, Gülmezoglu AM, Hofmeyr GJ, Coomarasamy A. Uterotonic agents for preventing postpartum haemorrhage: a network meta-analysis. Cochrane Database of Systematic Reviews 2018, Issue 4. Art. No.: CD011689. DOI: 10.1002/14651858.CD011689.pub2. General rights Unless a licence is specified above, all rights (including copyright and moral rights) in this document are retained by the authors and/or the copyright holders. The express permission of the copyright holder must be obtained for any use of this material other than for purposes permitted by law. •Users may freely distribute the URL that is used to identify this publication. •Users may download and/or print one copy of the publication from the University of Birmingham research portal for the purpose of private study or non-commercial research. •User may use extracts from the document in line with the concept of ‘fair dealing’ under the Copyright, Designs and Patents Act 1988 (?) •Users may not further distribute the material nor use it for the purposes of commercial gain. Where a licence is displayed above, please note the terms and conditions of the licence govern your use of this document. When citing, please reference the published version. Take down policy While the University of Birmingham exercises care and attention in making items available there are rare occasions when an item has been uploaded in error or has been deemed to be commercially or otherwise sensitive. If you believe that this is the case for this document, please contact [email protected] providing details and we will remove access to the work immediately and investigate. Download date: 10. Oct. 2021 Cochrane Database of Systematic Reviews Uterotonic agents for preventing postpartum haemorrhage: a network meta-analysis (Review) Gallos ID, Williams HM, Price MJ, Merriel A, Gee H, Lissauer D, Moorthy V, Tobias A, Deeks JJ, Widmer M, Tunçalp Ö, Gülmezoglu AM, Hofmeyr GJ, Coomarasamy A Gallos ID, Williams HM, Price MJ, Merriel A, Gee H, Lissauer D, Moorthy V, Tobias A, Deeks JJ, Widmer M, Tunçalp Ö, Gülmezoglu AM, Hofmeyr GJ, Coomarasamy A. Uterotonic agents for preventing postpartum haemorrhage: a network meta-analysis. Cochrane Database of Systematic Reviews 2018, Issue 4. Art. No.: CD011689. DOI: 10.1002/14651858.CD011689.pub2. www.cochranelibrary.com Uterotonic agents for preventing postpartum haemorrhage: a network meta-analysis (Review) Copyright © 2018 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd. TABLE OF CONTENTS HEADER....................................... 1 ABSTRACT ...................................... 1 PLAINLANGUAGESUMMARY . 3 SUMMARY OF FINDINGS FOR THE MAIN COMPARISON . ..... 4 BACKGROUND .................................... 7 OBJECTIVES ..................................... 8 METHODS ...................................... 8 Figure1. ..................................... 11 RESULTS....................................... 16 Figure2. ..................................... 17 Figure3. ..................................... 18 Figure4. ..................................... 20 Figure5. ..................................... 21 Figure6. ..................................... 22 Figure7. ..................................... 23 Figure8. ..................................... 24 Figure9. ..................................... 25 Figure10. ..................................... 26 Figure11. ..................................... 27 Figure12. ..................................... 28 Figure13. ..................................... 29 Figure14. ..................................... 30 Figure15. ..................................... 31 Figure16. ..................................... 32 Figure17. ..................................... 33 Figure18. ..................................... 34 Figure19. ..................................... 35 Figure20. ..................................... 36 Figure21. ..................................... 37 Figure22. ..................................... 38 Figure23. ..................................... 39 Figure24. ..................................... 40 Figure25. ..................................... 41 Figure26. ..................................... 42 Figure27. ..................................... 43 Figure28. ..................................... 44 Figure29. ..................................... 45 Figure30. ..................................... 46 Figure31. ..................................... 47 Figure32. ..................................... 48 Figure33. ..................................... 49 Figure34. ..................................... 50 Figure35. ..................................... 51 Figure36. ..................................... 52 Figure37. ..................................... 53 Figure38. ..................................... 54 Figure39. ..................................... 55 Figure40. ..................................... 56 Figure41. ..................................... 57 Figure42. ..................................... 58 Figure43. ..................................... 59 Uterotonic agents for preventing postpartum haemorrhage: a network meta-analysis (Review) i Copyright © 2018 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd. Figure44. ..................................... 60 Figure45. ..................................... 61 Figure46. ..................................... 62 Figure47. ..................................... 63 Figure48. ..................................... 64 Figure49. ..................................... 65 Figure50. ..................................... 66 Figure51. ..................................... 67 Figure52. ..................................... 68 Figure53. ..................................... 69 Figure54. ..................................... 70 Figure55. ..................................... 71 Figure56. ..................................... 72 Figure57. ..................................... 73 Figure58. ..................................... 74 Figure59. ..................................... 75 Figure60. ..................................... 76 Figure61. ..................................... 77 Figure62. ..................................... 78 Figure63. ..................................... 79 Figure64. ..................................... 80 Figure65. ..................................... 81 Figure66. ..................................... 82 Figure67. ..................................... 83 Figure68. ..................................... 84 Figure69. ..................................... 85 Figure70. ..................................... 86 Figure71. ..................................... 87 Figure72. ..................................... 88 Figure73. ..................................... 89 Figure74. ..................................... 90 Figure75. ..................................... 91 Figure76. ..................................... 92 Figure77. ..................................... 93 DISCUSSION ..................................... 93 AUTHORS’CONCLUSIONS . 95 ACKNOWLEDGEMENTS . 95 REFERENCES ..................................... 96 CHARACTERISTICSOFSTUDIES . 125 APPENDICES ..................................... 353 CONTRIBUTIONSOFAUTHORS . 354 DECLARATIONSOFINTEREST . 354 SOURCESOFSUPPORT . 355 DIFFERENCES BETWEEN PROTOCOL AND REVIEW . .... 356 Uterotonic agents for preventing postpartum haemorrhage: a network meta-analysis (Review) ii Copyright © 2018 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd. [Intervention Review] Uterotonic agents for preventing postpartum haemorrhage: a network meta-analysis Ioannis D Gallos1, Helen M Williams1, Malcolm J Price2, Abi Merriel3, Harold Gee4, David Lissauer5, Vidhya Moorthy6, Aurelio Tobias1, Jonathan J Deeks7, Mariana Widmer8, Özge Tunçalp8, Ahmet Metin Gülmezoglu8, G Justus Hofmeyr9, Arri Coomarasamy1 1Tommy’s National Centre for Miscarriage Research, Institute of Metabolism and Systems Research, University of Birmingham, Birm- ingham, UK. 2School of Health and Population Sciences, University of Birmingham, Birmingham, UK. 3Bristol Medical School, Uni- versity of Bristol, Southmead Hospital, UK. 4Birmingham, UK. 5School of Clinical and Experimental Medicine, University of Birming- ham, Birmingham, UK. 6Department of Obstetrics and Gynaecology, Sandwell and West Birmingham NHS Trust, Birmingham, UK. 7Institute of Applied Health Research, University of Birmingham, Birmingham, UK. 8UNDP/UNFPA/UNICEF/WHO/World Bank
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