Ethiopian Veterinary Journal 2016, 20 (1):55-66 Sero-prevalence of foot and mouth disease in cattle in Borena Zone, Oromia regional state, Ethiopia Asamenew Tesfaye1*, Mesfin Sehale1, Ashebir Abebe1, Ayelech Muluneh1and Daniel Gizaw1 1National Animal Health Diagnostic and Investigation Center (NAHDIC), P.O. Box 04, Sebeta, Ethiopia *Corresponding author: National Animal Health Diagnostic and Investigation Center, P.O. Box 04, Sebeta, Ethiopia, Email:
[email protected] http://dx.doi.org/10.4314/evj.v20i1.4 Abstract A cross-sectional study was carried out between April and November 2015 to in- vestigate the sero-prevalence of foot-and-mouth disease (FMD) in cattle in Borena zone using 3ABC-Enzyme Linked Immuno Sorbent Assay (ELISA) to detect anti- body against foot-and-mouth disease virus and semi structured questionnaire. A total of 363 sera samples were collected from nine peasant associations found in three different districts. An overall seroprevalence of 42.7% (95%: CI= 37.7-47.84) was found during the study. There was statistically significant difference among the districts (χ2 = 10.43, p=0.005) and the highest prevalence was found in Dire dis- trict which accounted for 52.8% (95%: CI, 44.0-61.4). The highest sero-prevalence was recorded in Soda peasant association of Dire district and Surupa peasant as- sociation of Yabello district which accounted for 65.5% (95%: CI, 49.4-78.5) and 65.0% (95%: CI= 40.4-78.5), respectively. Statistical significant difference in foot- and-mouth disease seroprevalence (χ2=31.1, p=0.000) was found among the peas- ant associations.