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Issue 1, Vaccination Progress and Changes in COVID-19 Containment

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Issue 1, Vaccination Progress and Changes in COVID-19 Containment 1 COVID-19 Containment Measures Analysis, Issue 1 | Vaccinations COVID - CONTAINMENT MEA URE ANALY I , I UE Vaccination Progress and Changes in COVID-19 Containment Measures Evidence-Based Public ,ealth -.I/ 01 | Center for International ,ealth Protection -.I/1 Robert 3och Institute 2 COVID-19 Containment Measures Analysis, Issue 1 | Vaccinations Vaccination Progress and Changes in COVID-19 Containment Measures Robert Koch-Institute, 2021 4unding This report was developed under the project Analysis of international epidemiological data and response measures, a project funded by the German Federal Ministry of Health (BMG). Authors Thurid Bahr, ZIG 2 Johanna Hanefeld, ZIG Charbel El-Bcheraoui, ZIG2 Ac5nowledgements The authors gratefully acknowledge Luisa Denkel, Angela Fehr and the Public Health Intelligence team for their valuable input and feedback on this report. uggested Citation Bahr, T., Hanefeld, J. and El-Bcheraoui, C., 2021. Vaccination Progress and Changes in COVID-19 Containment Measures in Chile, France, Germany, Israel, Italy, the United Kingdom and the United Arab Emirates, December – April 2021. Report. COVID-19 Containment Measures Analysis, Issue 1, Robert Koch Institute, Berlin. Disclaimer The content of this report expresses the opinions of its authors and does not necessarily represent the views of the Robert Koch Institute. 3 COVID-19 Containment Measures Analysis, Issue 1 | Vaccinations ummary This issue analyzes progress of national COVID-19 vaccination campaigns and COVID-19 containment measures in Chile, France, Germany, Israel, Italy, the United Kingdom (UK) and the United Arab Emirates (UAE). Weekly COVID-19 incidence per 100,000 population has been increasing slightly in the UAE, increasing strongly in Chile, France, Germany and Italy, decreasing slightly in the UK and decreasing strongly in Israel since early March 2021. France and Italy are currently experiencing an increase in weekly COVID-19 hospital occupancy whereas Israel and the UK are experiencing decreasing trends in hospital occupancy. Weekly COVID-19 intensive care unit (ICU) occupancy is also increasing in France, Germany and Italy whereas it is decreasing in Israel and the UK. Variant of concern (VoC) B.1.17 continues to increase and now accounts for at least 71 % of circulating variants in France, Germany, Israel, Italy and the UK. Vaccination campaigns are ongoing in all of the seven countries. As of 2 April 2021, 36.31, 46.29 and 60.72% of the population had received at least one dose of a COVID-19 vaccine in Chile, the UK, and Israel respectively. By the same date, 11.98, 12.27 and 13.37% of the population in Germany, Italy and France had received at least one dose. As of 23 February 2021, 35.2% of the population in the UAE had received at least one dose. All countries included in this analysis began their vaccination campaigns among prioritized vulnerable groups at the highest risk of developing severe disease or dying. All of them have expanded their vaccination campaigns over time to include more population groups. Israel is currently the only country to universally offer a vaccine to anyone in the population 16 years and older. Vaccine acceptance mostly increased between November 2020 and early March 2021 in France, Germany, Italy and the UK. Vaccine acceptance in Israel strongly decreased between November 2020 and February 2021 and slightly increased between end of February and early March 2021. Between December 2020 and April 2021, the seven countries most frequently tightened measures related to international travel, workplaces and schools. Israel loosened workplace closures, cancellations of public events, stay-at-home requirements and restrictions on internal movement between February and March 2021. In early March, the UK also started relaxing COVID-19 containment measures, amongst others for schools. COVID-19 vaccinations are crucial to reduce severe disease and the burden on health systems. In Israel and the UK, lesser severity of COVID-19 can be observed, as measured by COVID-19 hospital occupancy and COVID-19 ICU occupancy. VoC B.1.1.7 does not significantly reduce the effectiveness of the distributed vaccines. The effectiveness of distributed vaccines against VoC B.1.351 and P.1 is subject to ongoing research and currently available evidence suggests reduced effectiveness for some administered vaccine types. Relatively lower vaccination coverage, such as currently seen in France, Germany and Italy, coupled with heavy circulation of the virus in populations increases the risk that virus variants less susceptible to currently distributed vaccines may emerge. Therefore, countries with low vaccination coverage should urgently speed up vaccination campaigns to increase vaccination coverage. Declining vaccine acceptance can also affect the progress of national vaccination campaigns in countries with high and low vaccination coverage. Both issues require effective risk communication and community engagement around COVID-19 vaccines. Countries with high and low vaccination coverage should also uphold effective COVID-19 containment measures to contain virus circulation within country and limit across-country transmission. 4 COVID-19 Containment Measures Analysis, Issue 1 | Vaccinations .usammenfassung Die vorliegende Ausgabe behandelt den Fortschritt nationaler Impfkampagnen und von COVID-19 Eindämmungsmaßnahmen in Chile, Deutschland, Frankreich, Israel, Italien, den Vereinigten Arabischen Emiraten (VAE) und dem Vereinigten Königreich (VK). Seit Anfang März 2021 steigt die wöchentliche COVID- 19-Inzidenz pro 100.000 Einwohner in den VAE leicht an, in Chile, Frankreich, Deutschland und Italien stark an, hat im VK leicht abgenommen und in Israel stark abgenommen. Frankreich und Italien verzeichnen derzeit einen Anstieg der wöchentlichen COVID-19-Krankenhausbelegung, während Israel und Großbritannien einen rückläufigen Trend bei der Krankenhausbelegung verzeichnen. Die wöchentliche COVID-19 Intensivbelegung nimmt in Frankreich, Deutschland und Italien zu, während sie in Israel und im VK abnimmt. Die Virusvariante (VoC) B.1.17 macht inzwischen mindestens 71% der im Umlauf befindlichen Varianten in Frankreich, Deutschland, Israel, Italien und Großbritannien aus. Bis zum 2. April 2021 hatten 36,31, 46,29 und 60,72% der Bevölkerung in Chile, dem VK und Israel mindestens eine Dosis eines COVID-19-Impfstoffs erhalten. Zum gleichen Zeitpunkt hatten 11,98, 12,27 und 13,37% der Bevölkerung in Deutschland, Italien und Frankreich mindestens eine Dosis erhalten. Bis zum 23. Februar 2021 hatten 35,2% der Bevölkerung in den VAE mindestens eine Dosis erhalten. Alle untersuchten Länder begannen ihre Impfkampagnen unter priorisierten schutzbedürftigen Gruppen mit dem höchsten Risiko eines schweren Krankheitsverlaufes oder zu sterben. Alle Länder haben ihre Impfkampagnen im Laufe der Zeit auf mehr Bevölkerungsgruppen ausgeweitet. Israel ist derzeit das einzige Land, das allen Personen ab 16 Jahren ein Impfangebot macht. Insgesamt hat die Impfakzeptanz in Frankreich, Deutschland, Italien und Großbritannien zwischen November 2020 und Anfang März 2021 zugenommen, unterliegt aber Schwankungen. Die Impfakzeptanz in Israel nahm zwischen November 2020 und Februar 2021 stark ab und stieg zwischen Ende Februar und Anfang März 2021 leicht an. Zwischen Dezember 2020 und April 2021 haben die sieben Länder ihre Eindämmungsmaßnahmen bezüglich internationaler Reisen, Arbeitsplätzen und Schulen am häufigsten verschärft. Israel lockerte zwischen Februar und März 2021 Eindämmungsmaßnahmen an Arbeitsplätzen, für öffentliche Veranstaltungen und bezogen auf die Bewegungsfreiheit. Anfang März begann das VK ebenfalls, Maßnahmen zur Eindämmung von COVID-19 zu lockern, so zum Beispiel für Schulen. In Israel und dem VK, den beiden Ländern mit dem größten Impffortschritt (1. Dosis), ist der Schweregrad von COVID-19 Erkrankungen gemessen an der Krankenhaus- und Intensivbelegung geringer als in den anderen Ländern. Dies unterstreicht die Bedeutung von Impfungen als Maßnahme gegen schwere Krankheitsverläufe und die Überlastung von Gesundheitssystemen. VoC B.1.17 verringert die Wirksamkeit der in den sieben Ländern verimpften Impfstoffe nicht signifikant. Die Wirksamkeit verimpfter Impfstoffe gegen VoC B.1.351 und P.1 wird derzeit erforscht, und aktuell verfügbare Erkenntnisse deuten darauf hin, dass einige verabreichte Impfstofftypen weniger wirksam sind. Eine geringere Impfrate, wie sie derzeit in Frankreich, Deutschland und Italien zu beobachten ist, in Verbindung mit einer starken Zirkulation des Virus in der Bevölkerung erhöht das Risiko des Auftritts von Virusvarianten, gegen die derzeit verimpfte Impfstoffe weniger wirksam sind. Daher sollten Länder mit geringerer Impfrate ihre Impfkampagnen dringend beschleunigen. Eine sinkende Impfakzeptanz kann sich negativ auf den Impffortschritt in Ländern mit sowohl hoher als auch niedriger Impfrate auswirken. Beide Herausforderungen erfordern eine effektive Risikokommunikation und Bevölkerungsbeteiligung zu COVID-19-Impfstoffen. Länder mit hoher und Länder mit niedriger Impfrate sollten weiterhin effektive COVID-19-Eindämmungsmaßnahmen aufrechterhalten, um Viruszirkulation innerhalb des Landes einzudämmen und grenzüberschreitenden Viruseintrag zu begrenzen. 5 COVID-19 Containment Measures Analysis, Issue 1 | Vaccinations 1. Problem tatement Weekly COVID-19 incidence per 100,000 population has been increasing slightly in the UAE, increasing strongly in Chile, France, Germany and Italy, decreasing slightly in the UK and decreasing
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