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Forum:Pheromone Reviews - Real Reviews Written by Real People Thread: Meo Est - Toxicity? Forum:Pheromone Reviews - Real Reviews written by Real People Thread: Meo Est - Toxicity? Gslinger - November 27, 2011, 1:42 am Hi guys, I've gone through most posts on these boards as well as that on the ptalk board. Does anyone know if Meo Est or specifically the Methoxyestratetraenone that's being more commonly used in the products as well as single molecules that's being sold by pheromone companies and labs is toxic? What is the general consensus or the leading and highest possibility? Is it cancerous? What does toxic mean? Can it be absorbed into our blood stream? Its one heck of a great molecule and I really loved it up till when I started seeing the various posts on its toxicity. I'd like to know for sure I'm not caught in a situation where the risks outweigh the rewards, can anyone shed any light on this? dbot - November 27, 2011, 1:53 am Tisha claims the stuff is found in humans only in cancerous breast tissue. She got this idea from Diane, of Paradise7, who generally has a good grasp of the literature, but I am not aware of the source of the info and a search of Pubmed for "methoxyestratetraenone" turns up no results. Even if it is only produced by cancerous breast tissue. there is no reason to suspect that it might somehow cause breast cancer. But it probably does have some estrogenic activity, so I'd avoid using it on a very regular basis, lest ye gain weight and develop sensitive nipples ;) One thing the pheromone community suffers from far too much of is people developing very strong opinions based on minimal information, and repeating those opinions in increasingly fervent and persuasive ways. 2000GT - November 27, 2011, 2:17 am (11-26-2011 8:53 PM)dbot Wrote:  Tisha claims the stuff is found in humans only in cancerous breast tissue. She got this idea from Diane, of Paradise7, who generally has a good grasp of the literature, but I am not aware of the source of the info and a search of Pubmed for "methoxyestratetraenone" turns up no results. Even if it is only produced by cancerous breast tissue. there is no reason to suspect that it might somehow cause breast cancer. But it probably does have some estrogenic activity, so I'd avoid using it on a very regular basis, lest ye gain weight and develop sensitive nipples ;) One thing the pheromone community suffers from far too much of is people developing very strong opinions based on minimal information, and repeating those opinions in increasingly fervent and persuasive ways. And folks banging on about medical advice when they...wait..*gasps* aren't doctors! Not a dig at you dbot, just towards folks that like to give the all knowing attitude without at least some research. That's one of the things I like about this place, so many people do their own research and we have the vendors posting here as well, lending their experience. As far as the OP goes, I'd go with what dbot says. I've only ever used Methoxyestratetraenone in true love and so far I haven't had any results with it (too cold for the oil version), so I'm holding off on it for the time being. NewAlpha - November 27, 2011, 2:49 am Assuming there MAY be some form of toxicity, I wonder if spraying it on clothes to avoid direct contact with the skin, would help... dbot - November 27, 2011, 3:04 am @NewAlpha - If there is, it will, but probably at the expense of diffusion. Maybe spraying it on top of an undershirt, where it would still be exposed to a good amount of body heat? Alpha Dream - November 27, 2011, 3:18 am Meo-estratetraenone may very well be estrogenic. From what I know of steroid metabolism, 3-methoxy is reduced to 3-hydroxy. 3-hydroxy-estratetraenone is equilin, a horse steroid which is used for human postmenapausal therapy in the pharmaceutical 'Premarin.' Equilin and the entire estratetraenone family is all bad in my opinion - Their pheromone effect is too weak and side effects too great to be used in a responsible formula, in my humble opinion. 3-methoxy-estratetraenol should be relatively safe, from what I understand. The parent compound has been safetly used in perfumes for 20+ years with no adverse effects. I doubt either are any more cancerous than the estradiol in your body. Estradiol is actually a natural carcinogen (targeting breasts) which both men's but especially women's bodies naturally produce in abundance. Even our own bodies synthesize carcinogens.. dbot - November 27, 2011, 3:30 am Thanks for sharing your insights, Chris. I've been very curious about methoxy-estratetraenol. Can you say more about the parent compound being used in perfumes. Also, have you had a chance to experiment with this one for pheromonal properties? Alpha Dream - November 27, 2011, 4:15 am (11-26-2011 10:30 PM)dbot Wrote:  Can you say more about the parent compound being used in perfumes. the parent compound is estratetraenol (11-26-2011 10:30 PM)dbot Wrote:  Also, have you had a chance to experiment with this one for pheromonal properties? The only one who makes it is Molcan Corporation (also known as TP) .. Never had the pleasure of working with these guys... But from what I read, meo-estratetraenol is interesting stuff... Pagodeiro - November 27, 2011, 2:37 pm (11-26-2011 8:42 PM)Gslinger Wrote:  Hi guys, I've gone through most posts on these boards as well as that on the ptalk board. Does anyone know if Meo Estratetraenol or specifically the Methoxyestratetraenone that's being more commonly used in the products as well as single molecules that's being sold by pheromone companies and labs is toxic? What is the general consensus or the leading and highest possibility? Is it cancerous? What does toxic mean? Can it be absorbed into our blood stream? Its one heck of a great molecule and I really loved it up till when I started seeing the various posts on its toxicity. I'd like to know for sure I'm not caught in a situation where the risks outweigh the rewards, can anyone shed any light on this? Gslinger ..... have you been using Methoxy- estratetraenol from TP ? or are you referring to Methoxyestratetraenone ? when you say that it's on heck of a great molecule ? Pago mark-in-dallas - November 27, 2011, 3:10 pm dbot was right, in that Diane had a bad response to Methoxyestratetraenone and for that reason she decided to dig up any dirt she could find on it and preach it as gospel. And, Tisha latched on to that OPINION. Then there was that Methoxyestratetraenone was sold by Androtics in their experimone series, and Diane's venomous hatred for them didn't help its cause. Diane may be well studied in microbiology, but she does not have a degree in it, nor in any other medical or scientific field of study that I am aware of. I would take any unproven statements she's made with a grain of salt. Gslinger - November 29, 2011, 12:45 am Chris, Dbot, Mark, thanks guys, your information certainly helped. I guess on my side I'll use Methoxyestratetraenone with more caution from now on. Pago, TP uses Methoxyestratetraenone. Check out the technical information on their products dexter - November 29, 2011, 8:53 am I was reading this newer thread and think I should post a link to the old thread. https://pherotruth.com/Thread-Methoxyestratetraenone All this info was pulled from the thread above. Not my own work, i just edited. so 5 different molecules. They sound so similar. 1- Estratetraenone [Estra-1,3,5(10),8-tetraen-3-ol-17-one ]. TP sells Equilin (with one L) as Estratetraenone. 8,9-Dehydroestrone, or Δ8-estrone, aka estra-1,3,5(10),8-tetraen-3-ol-17-one CAS 474-87-3 [added 2017-01-03] 2- Equillin [1,3,5(10),7-Estratetraen-3-ol-17-one]. Equilin is Hydroxy-Estratetraenol. It is one of the components of Premarin (the main one, but not the only one). Equilin - Substance Summary (SID 24869978). https://www.medicinenet.com/estrogens_con...rticle.htm CAS 474-87-3 [added 2017-01-03] Quote: Conjugated estrogens are a mixture of several different estrogens (estrogen salts) that are derived from natural sources and blended to the approximate composition of estrogens in the urine of pregnant mares. The main components are sodium estrone sulphate and sodium equilin sulfate. tp://www.ncbi.nlm.nih.gov/pubmed/9344546 talks about equillin as it helps prevent alzheimers in women. 3- Methoxyestratetraenone aka Methoxyestratetraenone aka Estratetraenone Methyl Ether [1, 3, 5(10), 7-Estratetraen-3-ol-17-one methyl ether] is an Equilin analog derivative. CAS 6030-83-7 Estratetraenone Methyl Ether ; Methoxy Estratetraenone ; Methyl Estratetraenone ; 3-Methoxy-estra-1,3,5(10),8-tetraen-17-one [added 2017-01-03] 4- Methoxyestratetraenol aka Estratetraenol Methyl Ether[3-Methoxy-estra-1,3,5(10),16-tetraene] is sold at TP. is an Equilin analog derivative. CAS # 28336-31-4 ; [added 2017-01-03] 5- Estratetraenol [estra-1,3,5(10),16-tetraen-3-ol] CAS Number:1150-90-9. a derivative of estradiol. https://en.wikipedia.org/wiki/Estratetraenol Diane spoke of how Love-Scents' version of Equillin 1,3,5(10),7-Estratetraen-3-ol-17-one was in METHANOL, and the the methanol was highly toxic.
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